Infertility

Low AMH Level

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Re: Low AMH Level

  • But I couldn’t take the picture because I OF COURSE forgot my phone at my desk when I dropped off my coat and hat/scarf so I had to wrap the test back in a plastic bag and dumped and closed the pee cup and took it all back to my desk where I literally crawled under my desk, unwrapped the test and took a picture from down there so my coworker couldn’t see. His desk is basically attached to mine and our cubicle walls are only 12 inches high. He must have been like, what is she doing? I pretended I was trying to plug something in. Anyway doctor responded back within minutes bring like, you are good!  Fire drill over.   And then I forgot about the pee cup and walked around with it in my backpack until today!!!!!! Yuck! Hahaha:)

    The things we go through!  I can’t wait till we can truly laugh at all these stories when we finally have our babes in our arms. 
    Me: Hashimoto Autoimune Disease
    Homozygous MTHFR Cr677
    DOR - AMH  .27 High FSH (don't even know how high)
    2 iui's to start - BFN 
    IVF 1 -3 made it do day 5!    2 5AA 1 6BB  PGS results =  all abnormal :(
    IVF 2 - stimmed for 19 days. insanity. Had 5 follicles that looked mature but only 2 contained mature eggs the others were empty.  Nothing made it to day 5
    IVF 3 - added in HGH - 4 mature follicles (had some empties again) 3 made it to day 5/6 for PGS (held for testing with next retrieval
    IVF 4 - Upped my dosage for the first time - Canceled 11 days into sims - looked like 1 follicle and we were afraid it was empty
    IVF 5 - Canceled -  looked like 1 follicle and we were afraid it was empty
    IVF 6 - 3 mature, 2 fertalized 1 made it to day 5 and sent for PGS

    Sent in IVF round 3 and 6 (4 embryos) for PGS testing and got 2 normal embryos!!!  1Boy and 1Girl. Took a little over a year to get those two embryos so demanded all sorts of test prior to attempting transfer. Did EFT, ERA and NK Cells testing.

    FET#1 - Intralipid drips, Prednisone, and did a depot lupron shot before starting the FET protocol
    Chemical pregnancy
    FET#2 - PGS normal boy - BFN
    Natural pregnancy - cycle following the FET2????   Miscarriage at 8 weeks.  viability scan had shown an enlarged yolk sac so I had been warned that it was likely not chromosonally normal :(

    DEIVF cycle - picked a donor who is willing to be open! Her cycle resulted in in 4 PGS Normal embryos
    1st transfer - chemical pregnancy
    2nd transfer - success, May 17 2020 due date!
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  • @hopefuljj ohhhhh I sooooo needed to hear that story! That is awesome! And if your co-worker didn’t think you were mad before he sure does now! 

    As a side note, the only times I’ve seen a positive HPT are the squinters after trigger too. I’ve even kept those ones to compare against the ones I take eg now so if I am in any doubt if I see a line then I have a reference. Sadly the reference wasn’t needed so far.

    @adc0417 thanks for tour support too! How are things going with you? Any results yet?
    Me 43 DH 45
    Married 12/2016
    TTC #1 since 04/2015
    AMA, DOR (AMH 0.65, AFC 2-4) and autoimmune issues (RA, APS), low TSH, adenomyosis
    7 retrievals, 3 transfers
    Jun19 FET BFP, due date 7th March 2020, DD born Feb20
    Sep17 IVF1 - 1ER, 1F, 1ET, BFN
    Nov17 IVF2 - 1ER, 0F
    Jan18 IVF3 - 3ER, 1F, 1ET, BFN
    Feb18 - second opinion and additional testing
    Apr18 IVF4 - cancelled (E2 too high)
    May/Jun18 IVF4 - 4ER, 0M, 1F, 1 frozen day 3 (not best quality)
    Jun/Jul18 IVF5 - 5 ER, 3M, 2F, 2 frozen day 3 (not best quality)
    Jul/Aug18 IVF6 - 4ER, 3M, 2F, 2 frozen day 3 (good quality)
    Aug/Sep18 IVF7 - cancelled (cyst)
    Sep/Oct18 IVF7 - 3ER, 3M, 2F, 2 frozen Day 3 (excellent quality)
    Oct18 IVF8 - Cancelled (cyst and too low TSH)
    Oct18-Jan19 bringing TSH under control
    Feb19 ERA and hysteroscopy
    Mar19 Investigation for fibroid and adenomyosis
    Apr19 adenomyosis confirmed, polyps removed
    Jun19 FET after 2 months Lupron, autoimmune protocol, transferred two day 3 frozen embryos
    Sep17 - Pergoveris 10-17 Sep, Orgalutran 15-18 Sep, Ovitrelle 18 Sep, ER 20 Sep for 2 follies, 1 mature egg, fertilized, ET 1x 2d 4-cell embryo 22/09, 05/10 BFN
    Nov17 IVF2 - Pergoveris 2-14 Nov, Orgalutran 5-14 Nov, Ovitrelle 15 Nov, ER 17 Nov for 3 follies, 1 mature egg, did not fertilize
    Jan18 IVF3 - Pergoveris 30 Dec - 8 Jan, Orgalutran 5-8 Jan, Ovitrelle 9 Jan, ER 11 Jan 3 eggs, 2 mature, 1 fertilized, ET 1x 4d 12-cell embryo 15/01, 24/01 BFN
    May/Jun18 IVF4 - Rekovelle 25-29 May, Menogon 30May - 2Jun, Zomacton 25 27 29 31 May and 2Jun, Cetrotide 30May - 3Jun, Gonasi 3Jun, ER 5Jun 4 eggs, none mature, two matured overnight, 1 fertilized with ICSI, Frozen day 3 but not good quality
    Jun/Jul18 IVF5 - Rekovelle 21-24 June, Menogon 25Jun-3Jul, Puregon 4-5Jul, Zomacton 21 23 25 27 29 Jun, Cetrotide 25Jun-5Jul, Gonasi 6Jul, ER 8Jul 5 eggs, 3 mature, 2 fertilized with ICSI, 2 frozen day 3 but not good quality
    Jul/Aug18 IVF6 - Rekovelle 26-29 Jul, Menogon 30Jul-7Aug, Buserelin 26Jul-7Aug, Zomacton 26 28 30 Jul 1 3 Aug, Gonasi 7Aug, ER 9Aug 4 eggs, 3 mature, 2 fertilized (normal IVF), 2 frozen day 3 good quality
    Sep/Oct18 IVF7 - Menogon 19-30Sep, Buserelin 19-30Sep, Zomacton 19 21 23 25 27 Sep, Ovitrelle 1 Oct, ER 3 eggs, 3 mature, 2 fertilized with ICSI, 2 frozen day 3 excellent quality 

    Fav Quote: The greatest thing you'll ever learn is just to love and be loved in return

  • @emmasemm I'm so sorry you're still getting stark white tests :( Hopefully it's just early! I do definitely understand wanting to do the research already, though. And yes, my appointment is tomorrow. I'll update after with all of the results.
    Me: 36 | DH: 35 | Married: 9.17.16
    Diminished ovarian reserve
    BFP: 4/14/2020 EDD: 12/20/2020
  • @dreamscapes_ good luck for tomorrow! You must be west coast if you’re still awake now!

    At the whole active and lurker gang - has anyone had inconsistent AMH results?
    My level was 0.65 in July when we first went to the RE.
    My PCP ran it in January whilst I was stimming (which should have no effect) and it was 0.52 (so down a bit in six months, but kind of within different lab tolerance limits I guess).
    But then yesterday when I got a copy (finally) of my BW from October with my RE (immediately following my first failed IVF cycle) it was 0.91!

    Has anyone heard that AMH can fluctuate and particularly that it might be higher in the cycle following stim cycle? I thought it was supposed to be stable or reducing.
    Is that the reason why there is speculation that you’re more fertile in the natural cycle immediately following a stim cycle? Or why back to back cycles might help us low AMHers? 
    (In the same BW my FSH day 3 was only 8.7 compared to around 14-16 from April to July)

    Me 43 DH 45
    Married 12/2016
    TTC #1 since 04/2015
    AMA, DOR (AMH 0.65, AFC 2-4) and autoimmune issues (RA, APS), low TSH, adenomyosis
    7 retrievals, 3 transfers
    Jun19 FET BFP, due date 7th March 2020, DD born Feb20
    Sep17 IVF1 - 1ER, 1F, 1ET, BFN
    Nov17 IVF2 - 1ER, 0F
    Jan18 IVF3 - 3ER, 1F, 1ET, BFN
    Feb18 - second opinion and additional testing
    Apr18 IVF4 - cancelled (E2 too high)
    May/Jun18 IVF4 - 4ER, 0M, 1F, 1 frozen day 3 (not best quality)
    Jun/Jul18 IVF5 - 5 ER, 3M, 2F, 2 frozen day 3 (not best quality)
    Jul/Aug18 IVF6 - 4ER, 3M, 2F, 2 frozen day 3 (good quality)
    Aug/Sep18 IVF7 - cancelled (cyst)
    Sep/Oct18 IVF7 - 3ER, 3M, 2F, 2 frozen Day 3 (excellent quality)
    Oct18 IVF8 - Cancelled (cyst and too low TSH)
    Oct18-Jan19 bringing TSH under control
    Feb19 ERA and hysteroscopy
    Mar19 Investigation for fibroid and adenomyosis
    Apr19 adenomyosis confirmed, polyps removed
    Jun19 FET after 2 months Lupron, autoimmune protocol, transferred two day 3 frozen embryos
    Sep17 - Pergoveris 10-17 Sep, Orgalutran 15-18 Sep, Ovitrelle 18 Sep, ER 20 Sep for 2 follies, 1 mature egg, fertilized, ET 1x 2d 4-cell embryo 22/09, 05/10 BFN
    Nov17 IVF2 - Pergoveris 2-14 Nov, Orgalutran 5-14 Nov, Ovitrelle 15 Nov, ER 17 Nov for 3 follies, 1 mature egg, did not fertilize
    Jan18 IVF3 - Pergoveris 30 Dec - 8 Jan, Orgalutran 5-8 Jan, Ovitrelle 9 Jan, ER 11 Jan 3 eggs, 2 mature, 1 fertilized, ET 1x 4d 12-cell embryo 15/01, 24/01 BFN
    May/Jun18 IVF4 - Rekovelle 25-29 May, Menogon 30May - 2Jun, Zomacton 25 27 29 31 May and 2Jun, Cetrotide 30May - 3Jun, Gonasi 3Jun, ER 5Jun 4 eggs, none mature, two matured overnight, 1 fertilized with ICSI, Frozen day 3 but not good quality
    Jun/Jul18 IVF5 - Rekovelle 21-24 June, Menogon 25Jun-3Jul, Puregon 4-5Jul, Zomacton 21 23 25 27 29 Jun, Cetrotide 25Jun-5Jul, Gonasi 6Jul, ER 8Jul 5 eggs, 3 mature, 2 fertilized with ICSI, 2 frozen day 3 but not good quality
    Jul/Aug18 IVF6 - Rekovelle 26-29 Jul, Menogon 30Jul-7Aug, Buserelin 26Jul-7Aug, Zomacton 26 28 30 Jul 1 3 Aug, Gonasi 7Aug, ER 9Aug 4 eggs, 3 mature, 2 fertilized (normal IVF), 2 frozen day 3 good quality
    Sep/Oct18 IVF7 - Menogon 19-30Sep, Buserelin 19-30Sep, Zomacton 19 21 23 25 27 Sep, Ovitrelle 1 Oct, ER 3 eggs, 3 mature, 2 fertilized with ICSI, 2 frozen day 3 excellent quality 

    Fav Quote: The greatest thing you'll ever learn is just to love and be loved in return

  • @emmasemm I'm actually east coast! I had just fallen asleep around 3:30pm and woke up around 10:30pm. I was up for a couple of hours and then fell back asleep :) Also, not a single clue about the inconsistent AMH results.
    Me: 36 | DH: 35 | Married: 9.17.16
    Diminished ovarian reserve
    BFP: 4/14/2020 EDD: 12/20/2020
  • @dreamscapes_ - hope you have a good meeting with your RE today and come up with a plan!!

    @hopefuljj- omg your story is so funny! Our lives are seriously like a sitcom (or drama somedays I guess)! I am so glad you got it taken care of it, but I can only imagine taking a picture under my desk! I work in corporate open concept too. I am always taking doctor calls in the hallways and stair wells. Can't wait to hear your update  tomorrow!!

    @emmasemm- stark white is the WORST. I have never tested after trigger, so I have never seen two lines at all. I seriously have a breakdown when I POAS before beta. i don't want to do it, but I also can't take a day off work and wait for the REs call. Its just the most horrible thing... putting so much time and energy and money into this to be so devastated over and over. If I know you, you are already on top of figuring out your next clinic. Any forerunners? As far as AMH results, mine has stayed consistent over the two times I had it tested. I have heard that vitamin D levels can effect it. I don't think swings, up or down, are very meaningful, unless you have a correlated change in AFC. I think AFC is way more important than AMH. Even more important than AFC is quality, in my opinion. I had decent AMH (1.5 at 28/29), AFC of 9-14, and still I am on DE since I just can't get my embryos to blast or the few that make it there haven't stuck. So I am a firm believer in quality over quantity and while you only get a couple of eggs each time, I believe if you keep at it, you can find the golden egg!
    History in Spoiler

    Age: 32 (same with DH). Together since 2006, Married June 2013 and TTC since August 2015
    Diagnosis: Mild Endo, DOR (AMH of 1.5), Poor Quality Eggs/embryos, Displaced Window of Implantation (ERA Post Receptive)
    March-May 2016: 1 TI and 2 IUIs- BFN 
    June 2016- Laproscopy- found/removed mild endo and confirmed only 1 normal healthy ovary.
    August 2016- IVF #1 with Antagonist Protocol- Cancelled (2 lead follies), converted to IUI- BFN
    Oct-Nov 2016- IVF #2 with Estrogen Priming Micro Lupron Protocol, 2 eggs retrieved, day 3 transfer of 1- BFN
    January 2017- New RE, IVF#3 with Estrogen Priming Antagonist Protocol, 12 eggs, 8 mature, 6 fertilized, 2 day 5 early blasts transferred (none to freeze :(), BFN
    May 2017- Sept 2017- Starting Donor Egg process! Waiting for donor to be available... and then she is pregnant at baseline :(
    Oct 2017- Donor #2: 25R, 22M,18F, 12 blasts frozen! Fresh transfer cancelled due to thin lining with fluid :(
    Nov 2017- Hysterscopy to remove polyp
    Dec 2017- DE FET #1 on 12/8 on 2 perfect blasts- BFN and devastated
    Jan-Mar 2018- ERA #1- Post receptive by 24 hours, ERA #2 RECEPTIVE with 4 days of Progesterone
    Apr 2018- DE FET cancelled for lining issues :(
    Jun 2018- DE FET #2 of two 1AA blasts- first BFP ever! Beta 10dp5dt- 378, Beta 14dp5dt- 2840, Beta 16dp5dt- 4035, beta 18dp5dt- 10916. Due on 2/20 with one baby after a vanishing twin
    Baby Born born early @ 33.5 weeks due to Pre-e
    Back for # 2!
  • @emmasemm I actually have not had my AMH checked since Oct 2016.  I just figured if I'm not responding well to the IVF meds, then it doesn't really make much of a difference as to what my AMH is.  I too have heard that Vit D can increase your AMH.
    AFM, I finished my mock estrogen and now waiting for AF.  I hope I can enter the next IVF cycle...lets see what destiny has in store for me.
  • @hopefuljj dear lord!! Glad you made it to the bathroom in time...my bladder is just not strong enough to drink at home before going anywhere my hat off to you!!  And I felt your pain with this dang app from the phone!  I will say when I write something lengthy I try to remember to copy all before posting as I have lost so much and its the most frustrating!!!  But thanks for taking the time to share!  This is probably why my clinic just makes you come in for blood work to make sure the trigger was done correctly....which I say is great now BUT I know when it was time I just rather take the test...no pleasing me  :D

    @emmasemm ugh wish that squinter would just show up already!  I love that DH is staying positive I get the disappointment BUT why not try and be a lil happpy the few days a month you can get during this process.  In answer to your AMH question I"m not sure about the stemming and all that and what it can do etc.  I've done back to back cycles and not sure the previous stemming has helped or not.  I will say I do believe that the supplements that we're taking are suppose to help and i think if your AMH does go up it could be from that.  I do think .9 is a great jump and so close to normal soooo that should make you happy.  Mine started out as .30 and after a year i would say it was .40 and I was quite happy with my lil point higher ;)  Once your pregnant you stop taking the supplements and then the AMH has gone down for some....so to me that made it clear that the supplements do help...hope that help shed some light ;)
    History of TTC in spoiler box
    TTC since 2014
    Unexplained Infertility - but I am 40...Low AMH .30
    7 - IUI (50mg-150mg Clomid) Feb - August 2016 all BFN 
    IVF#1 August 2016 (Antagonist protocol 4/5 eggs) Cancelled cycle :( RE thought I would get at least 10.
    IVF#2 Sept 2016 (microdose luporn pro - disappearing follies, ONLY ONE, convert to IUI) BFN
    IVF#3 November 2016 (4 ER, 3 F,  3DT)-BFP  with TWINS // MC both at almost 10wks  :'( 
    IVF#4 March 2017 //EPP  (10 ER (1 wonky so 9 ER) 7F, 3B (5AB, (2)5BB) PGS tested- ALL abnormal  :'( 
    IVF#5 April 2017 // EPP (7 ER, 7F yes! 6B) 2/5 day 4/6 day - 2 PGS normal! yes!! :)
    IVF#6 May 2017 // Antagonist didn't have time for Estrogen Priming...(4 ER, 3 F, 3B) (5AB, (2) 5BB) 2 PGS normal, yes!! :)
    IVF#7 June 2017 // EPP praying this is it and then on to an FET!

  • So my test results. 

    - My AMH has doubled, but is still low at 0.67. The cyst is gone, so we think that may be a factor. 
    - DH’s SA was okay. His volume and motility are good, while his morphology and concentration are slightly low. 
    - My estrogen is slightly low, and my FSH was good. 
    - He said with these results, our options if we continue to have trouble are IVF or a medicated IUI. HOWEVER. 
    - His office will not perform any further procedures on me until I get my BMI below 43. It is currently 50. They want me to drop a minimum of 75 pounds in order to work with them. Why they didn’t tell us this at the initial appointment, we do not know. 
    - Given my back, hip, and foot issues, it’s incredibly difficult for me to work out and lose weight. I’ve been trying to lose weight for 25 years and have tried everything under the sun except for bariatric surgery. It’s next to impossible for me to do so. 

    We don’t know what we’re going to do at this point beyond continue trying.
    Me: 36 | DH: 35 | Married: 9.17.16
    Diminished ovarian reserve
    BFP: 4/14/2020 EDD: 12/20/2020
  • @dreamscapes_ good news on the AMH! But that’s really crappy that they never mentioned BMI limits for treatment to you earlier!!! Do you have other clinics close to you to try for a second opinion?
    I’m so sorry they did this to you. 

    If you’re looking for alternatives which allow you some intervention maybe to see if it helps with getting the sperm close to the right place at the right time, have you looked into something like Mosey Baby? 
    Me 43 DH 45
    Married 12/2016
    TTC #1 since 04/2015
    AMA, DOR (AMH 0.65, AFC 2-4) and autoimmune issues (RA, APS), low TSH, adenomyosis
    7 retrievals, 3 transfers
    Jun19 FET BFP, due date 7th March 2020, DD born Feb20
    Sep17 IVF1 - 1ER, 1F, 1ET, BFN
    Nov17 IVF2 - 1ER, 0F
    Jan18 IVF3 - 3ER, 1F, 1ET, BFN
    Feb18 - second opinion and additional testing
    Apr18 IVF4 - cancelled (E2 too high)
    May/Jun18 IVF4 - 4ER, 0M, 1F, 1 frozen day 3 (not best quality)
    Jun/Jul18 IVF5 - 5 ER, 3M, 2F, 2 frozen day 3 (not best quality)
    Jul/Aug18 IVF6 - 4ER, 3M, 2F, 2 frozen day 3 (good quality)
    Aug/Sep18 IVF7 - cancelled (cyst)
    Sep/Oct18 IVF7 - 3ER, 3M, 2F, 2 frozen Day 3 (excellent quality)
    Oct18 IVF8 - Cancelled (cyst and too low TSH)
    Oct18-Jan19 bringing TSH under control
    Feb19 ERA and hysteroscopy
    Mar19 Investigation for fibroid and adenomyosis
    Apr19 adenomyosis confirmed, polyps removed
    Jun19 FET after 2 months Lupron, autoimmune protocol, transferred two day 3 frozen embryos
    Sep17 - Pergoveris 10-17 Sep, Orgalutran 15-18 Sep, Ovitrelle 18 Sep, ER 20 Sep for 2 follies, 1 mature egg, fertilized, ET 1x 2d 4-cell embryo 22/09, 05/10 BFN
    Nov17 IVF2 - Pergoveris 2-14 Nov, Orgalutran 5-14 Nov, Ovitrelle 15 Nov, ER 17 Nov for 3 follies, 1 mature egg, did not fertilize
    Jan18 IVF3 - Pergoveris 30 Dec - 8 Jan, Orgalutran 5-8 Jan, Ovitrelle 9 Jan, ER 11 Jan 3 eggs, 2 mature, 1 fertilized, ET 1x 4d 12-cell embryo 15/01, 24/01 BFN
    May/Jun18 IVF4 - Rekovelle 25-29 May, Menogon 30May - 2Jun, Zomacton 25 27 29 31 May and 2Jun, Cetrotide 30May - 3Jun, Gonasi 3Jun, ER 5Jun 4 eggs, none mature, two matured overnight, 1 fertilized with ICSI, Frozen day 3 but not good quality
    Jun/Jul18 IVF5 - Rekovelle 21-24 June, Menogon 25Jun-3Jul, Puregon 4-5Jul, Zomacton 21 23 25 27 29 Jun, Cetrotide 25Jun-5Jul, Gonasi 6Jul, ER 8Jul 5 eggs, 3 mature, 2 fertilized with ICSI, 2 frozen day 3 but not good quality
    Jul/Aug18 IVF6 - Rekovelle 26-29 Jul, Menogon 30Jul-7Aug, Buserelin 26Jul-7Aug, Zomacton 26 28 30 Jul 1 3 Aug, Gonasi 7Aug, ER 9Aug 4 eggs, 3 mature, 2 fertilized (normal IVF), 2 frozen day 3 good quality
    Sep/Oct18 IVF7 - Menogon 19-30Sep, Buserelin 19-30Sep, Zomacton 19 21 23 25 27 Sep, Ovitrelle 1 Oct, ER 3 eggs, 3 mature, 2 fertilized with ICSI, 2 frozen day 3 excellent quality 

    Fav Quote: The greatest thing you'll ever learn is just to love and be loved in return

  • @dreamscapes_ - That is soo frustrating they didn't mention the BMI at the first appointment. Are there other REs in the area you can try? I know both of the clinics I have done IVF at have a BMI requirement too. However, my first RE who was a small 1 RE clinic was not as strict on a lot of things, so maybe try to find a boutique like clinic? The rest of the numbers don't sound too bad, so as long as you are ovulating monthly, I think there is a chance it could just happen naturally, especially since you are younger. There is also research that losing even 10% of your body weight can improve fertility, so perhaps that could help you naturally as you work toward the lower BMI goal for treatment. 
    History in Spoiler

    Age: 32 (same with DH). Together since 2006, Married June 2013 and TTC since August 2015
    Diagnosis: Mild Endo, DOR (AMH of 1.5), Poor Quality Eggs/embryos, Displaced Window of Implantation (ERA Post Receptive)
    March-May 2016: 1 TI and 2 IUIs- BFN 
    June 2016- Laproscopy- found/removed mild endo and confirmed only 1 normal healthy ovary.
    August 2016- IVF #1 with Antagonist Protocol- Cancelled (2 lead follies), converted to IUI- BFN
    Oct-Nov 2016- IVF #2 with Estrogen Priming Micro Lupron Protocol, 2 eggs retrieved, day 3 transfer of 1- BFN
    January 2017- New RE, IVF#3 with Estrogen Priming Antagonist Protocol, 12 eggs, 8 mature, 6 fertilized, 2 day 5 early blasts transferred (none to freeze :(), BFN
    May 2017- Sept 2017- Starting Donor Egg process! Waiting for donor to be available... and then she is pregnant at baseline :(
    Oct 2017- Donor #2: 25R, 22M,18F, 12 blasts frozen! Fresh transfer cancelled due to thin lining with fluid :(
    Nov 2017- Hysterscopy to remove polyp
    Dec 2017- DE FET #1 on 12/8 on 2 perfect blasts- BFN and devastated
    Jan-Mar 2018- ERA #1- Post receptive by 24 hours, ERA #2 RECEPTIVE with 4 days of Progesterone
    Apr 2018- DE FET cancelled for lining issues :(
    Jun 2018- DE FET #2 of two 1AA blasts- first BFP ever! Beta 10dp5dt- 378, Beta 14dp5dt- 2840, Beta 16dp5dt- 4035, beta 18dp5dt- 10916. Due on 2/20 with one baby after a vanishing twin
    Baby Born born early @ 33.5 weeks due to Pre-e
    Back for # 2!
  • @emmasemm Yeah, DH and I are not at all happy that they didn't bother telling us that until we went through all of the initial testing. We have another clinic that takes our insurance, but we'd have to get another referral and then probably go through all the testing all over again. So... We'll see what happens. I'll have to look into that Mosey Baby thing. Right now, we're just kind of putting all of this out of our heads.

    @JamieH2000 We're gonna talk about the possibility of a second opinion, but not tonight. As far as the weight loss thing, it's been a lifelong thing. I'm actually quite comfortable with my body and everything, but some doctors point toward my weight as causing everything.

    Me: 36 | DH: 35 | Married: 9.17.16
    Diminished ovarian reserve
    BFP: 4/14/2020 EDD: 12/20/2020
  • @dreamscapes_ good news on ur numbers thats promising!!  I echo the others thoughts annoying about the BMI for sure!!!  Of course it shouldve been mentioned BUT how many people that are obese still have kids naturally!  Yes it could help but that can't be the only reason as to why you can't get pregnant.  You should know I asked my RE at our first meeting together about weight and she didn't think that was my issue...granted I think my BMI at the time was under 30 but still overweight nonetheless. Now lets fast forward through all my medicated iuis and IVF cycles i was probably 25lbs heavier at the time of transfer with this lil babe of mine so I wouldn't count u out just yet :)  Find another Dr and even ask that question prior to meeting with them.  A new clinic will want to run tests however since you did just have them done i'm sure if you get a copy over to them that might be good enough.  This is just one of the many bumps in the road of Infertility - hang in there!
    History of TTC in spoiler box
    TTC since 2014
    Unexplained Infertility - but I am 40...Low AMH .30
    7 - IUI (50mg-150mg Clomid) Feb - August 2016 all BFN 
    IVF#1 August 2016 (Antagonist protocol 4/5 eggs) Cancelled cycle :( RE thought I would get at least 10.
    IVF#2 Sept 2016 (microdose luporn pro - disappearing follies, ONLY ONE, convert to IUI) BFN
    IVF#3 November 2016 (4 ER, 3 F,  3DT)-BFP  with TWINS // MC both at almost 10wks  :'( 
    IVF#4 March 2017 //EPP  (10 ER (1 wonky so 9 ER) 7F, 3B (5AB, (2)5BB) PGS tested- ALL abnormal  :'( 
    IVF#5 April 2017 // EPP (7 ER, 7F yes! 6B) 2/5 day 4/6 day - 2 PGS normal! yes!! :)
    IVF#6 May 2017 // Antagonist didn't have time for Estrogen Priming...(4 ER, 3 F, 3B) (5AB, (2) 5BB) 2 PGS normal, yes!! :)
    IVF#7 June 2017 // EPP praying this is it and then on to an FET!

  • @Hopeful_mom Yeah, we are not at all happy about that. Fat women get pregnant all the time ("fat" for me isn't a four letter word). We're going to talk about the possibility of a second opinion and everything, but I don't know when. It's just frustrating. We're still going to try on our own (annoyingly, AF is about to show her face >.<), and I need to get another pack of ovulation tests. But yeah, my ovaries are stupid.
    Me: 36 | DH: 35 | Married: 9.17.16
    Diminished ovarian reserve
    BFP: 4/14/2020 EDD: 12/20/2020
  • hopefuljjhopefuljj member
    edited January 2018
    @dreamscapes_ I’m so sorry they were not transparent with this info from the beginning!!! I can imagine you must be very frustrated:( I’m so sorry:(


     AFM 1 made it to blast and was biopsied and frozen. So over the course of 9 months and many cycles I ended up with 7 embryos to biopsy. I had one more slot in my DOR package which expires in 2 weeks but it would cost almost $1000 to thaw and re-biopsy one of my abnormal embryos from cycle 1 so I don’t think it’s worth it. So this is it. Now I wait for PGS results for the 4 embryos (3 from cycle 2 and 1 from this cycle). If nothing is normal like when I sent in the first 3 then maybe I’ll try a fresh transfer before moving on to adoption. Don’t know just yet:). Has anyone watched the one more shot documentary on Netflix? I’m thinking of watching it....my sister screened it for me and said she thinks I should.
    Me: Hashimoto Autoimune Disease
    Homozygous MTHFR Cr677
    DOR - AMH  .27 High FSH (don't even know how high)
    2 iui's to start - BFN 
    IVF 1 -3 made it do day 5!    2 5AA 1 6BB  PGS results =  all abnormal :(
    IVF 2 - stimmed for 19 days. insanity. Had 5 follicles that looked mature but only 2 contained mature eggs the others were empty.  Nothing made it to day 5
    IVF 3 - added in HGH - 4 mature follicles (had some empties again) 3 made it to day 5/6 for PGS (held for testing with next retrieval
    IVF 4 - Upped my dosage for the first time - Canceled 11 days into sims - looked like 1 follicle and we were afraid it was empty
    IVF 5 - Canceled -  looked like 1 follicle and we were afraid it was empty
    IVF 6 - 3 mature, 2 fertalized 1 made it to day 5 and sent for PGS

    Sent in IVF round 3 and 6 (4 embryos) for PGS testing and got 2 normal embryos!!!  1Boy and 1Girl. Took a little over a year to get those two embryos so demanded all sorts of test prior to attempting transfer. Did EFT, ERA and NK Cells testing.

    FET#1 - Intralipid drips, Prednisone, and did a depot lupron shot before starting the FET protocol
    Chemical pregnancy
    FET#2 - PGS normal boy - BFN
    Natural pregnancy - cycle following the FET2????   Miscarriage at 8 weeks.  viability scan had shown an enlarged yolk sac so I had been warned that it was likely not chromosonally normal :(

    DEIVF cycle - picked a donor who is willing to be open! Her cycle resulted in in 4 PGS Normal embryos
    1st transfer - chemical pregnancy
    2nd transfer - success, May 17 2020 due date!
  • Quick update...DH was out after work today so When I got home I just cried my way through the documentary.  Touches on all the ways to complete your family.  Beautiful. But also like really hard to watch without sobbing.  The main character has DOR.  
    Me: Hashimoto Autoimune Disease
    Homozygous MTHFR Cr677
    DOR - AMH  .27 High FSH (don't even know how high)
    2 iui's to start - BFN 
    IVF 1 -3 made it do day 5!    2 5AA 1 6BB  PGS results =  all abnormal :(
    IVF 2 - stimmed for 19 days. insanity. Had 5 follicles that looked mature but only 2 contained mature eggs the others were empty.  Nothing made it to day 5
    IVF 3 - added in HGH - 4 mature follicles (had some empties again) 3 made it to day 5/6 for PGS (held for testing with next retrieval
    IVF 4 - Upped my dosage for the first time - Canceled 11 days into sims - looked like 1 follicle and we were afraid it was empty
    IVF 5 - Canceled -  looked like 1 follicle and we were afraid it was empty
    IVF 6 - 3 mature, 2 fertalized 1 made it to day 5 and sent for PGS

    Sent in IVF round 3 and 6 (4 embryos) for PGS testing and got 2 normal embryos!!!  1Boy and 1Girl. Took a little over a year to get those two embryos so demanded all sorts of test prior to attempting transfer. Did EFT, ERA and NK Cells testing.

    FET#1 - Intralipid drips, Prednisone, and did a depot lupron shot before starting the FET protocol
    Chemical pregnancy
    FET#2 - PGS normal boy - BFN
    Natural pregnancy - cycle following the FET2????   Miscarriage at 8 weeks.  viability scan had shown an enlarged yolk sac so I had been warned that it was likely not chromosonally normal :(

    DEIVF cycle - picked a donor who is willing to be open! Her cycle resulted in in 4 PGS Normal embryos
    1st transfer - chemical pregnancy
    2nd transfer - success, May 17 2020 due date!
  • @emmasemm my amh went up about a month after my second ivf cycle, which was cancelled due to the embryos arresting.   A few months later it went down some.  I don’t know if it went up due to the supplements I started after the failed cycle or something else.  I’m not entirely convinced that amh levels tell us much.  It can be artificially suppressed if your vitamin d level is low.  That is an interesting idea, though.  I agree with @JamieH2000 , quality is really the important factor.  I don’t know if dhea, acupuncture, the vitamin d, or the epp made fourth cycle successful, but if I were to do ivf again, I’d do all of those things.

    @JamieH2000 hoping for a great update tomorrow!
    Me:32 DH:36
    Me: DOR, poor egg quality, MTHFR
    DH: MFI
    TTC since 3/2014
    2015: 3 IUI's-BFN
    12/2015: 1st IVF cycle-(9 follicles retrieved, 5 mature, 3 fertilized w/ICSI, transferred 1 excellent and 1 good embryo on day 3)-chemical pregnancy
    3/2016: 2nd IVF cycle- canceled (3 follicles retrieved, 3 mature, all fertilized w/ICSI, 1 fragmented, 2 arrested) 
    3/2016: RE suggested donor eggs- taking an ivf break and to supplement 
    9/2016: 3rd ivf cycle-cancelled due to early ovulation
    Oct./Nov 2016: 4th ivf cycle- EPP-AFC:5, retrieved 10, 10 mature, 8 fertilized with ICSI, 6 blastocysts biopsied and frozen. 3 CCS normal embryos
    1/9/17: transferred 1 embryo-BFP 1/16
    1/18/17: beta #1-104
    1/20/17: beta #2-174
    2/2/17: first u/s, heartbeat of 107 at 6w1d
    7/20/17: baby boy born at 30+3 via emergency c-section 


  • @hopefuljj yay for having another blast! Fx for your testing now!
    Also with your “abnormalste” did they say what the abnormalities were? Because some abnormalities can be less serious. And some would normally mean the embie won’t make it to blast or won’t implant - so as they have made it blast, if you put them back you’d “only” risk a BFN (or CP) but nothing else. And if they do go on they’re likely to have been mosaics and turn out ok.
    It also seems to very much depend which PGS testing technique they’ve used as some are really much more accurate than others.
    Just something to discuss with your clinic... 

    @kp214 yeah it’s also made me wonder more about the AMH thing, which of course is billed as much better than just using FSH. But the other thing is that my PCP this week at my new patient health check found my VitD levels are basically undetectable. She says even ladies in their 20s don’t get KU with those levels, so I have an appointment next week to go through those and some other crazy levels with her and try to decide what we do to at least have my body functioning normally in general. I do live in Northern Europe and we don’t see much sun in the winter, but undetectable... 
    My AFC has never been super high, but has varied from 2 to 5. And if I could guarantee 5 each time by having vitamin levels right then I would take that no question! 
    I’m doing acupuncture since September so that could also be a part... but didn’t do any before the last BW as it was Xmas holidays for 3 weeks which corresponds with worse numbers again...
    I just took Estrogen during my TWW after the last transfer, so very interested to see how this cycle plays out naturally after that. DH is ready to do his part every day during FW!
    Thanks a lot for taking the time to answer!

    @jamieh2000 fx!

    Me 43 DH 45
    Married 12/2016
    TTC #1 since 04/2015
    AMA, DOR (AMH 0.65, AFC 2-4) and autoimmune issues (RA, APS), low TSH, adenomyosis
    7 retrievals, 3 transfers
    Jun19 FET BFP, due date 7th March 2020, DD born Feb20
    Sep17 IVF1 - 1ER, 1F, 1ET, BFN
    Nov17 IVF2 - 1ER, 0F
    Jan18 IVF3 - 3ER, 1F, 1ET, BFN
    Feb18 - second opinion and additional testing
    Apr18 IVF4 - cancelled (E2 too high)
    May/Jun18 IVF4 - 4ER, 0M, 1F, 1 frozen day 3 (not best quality)
    Jun/Jul18 IVF5 - 5 ER, 3M, 2F, 2 frozen day 3 (not best quality)
    Jul/Aug18 IVF6 - 4ER, 3M, 2F, 2 frozen day 3 (good quality)
    Aug/Sep18 IVF7 - cancelled (cyst)
    Sep/Oct18 IVF7 - 3ER, 3M, 2F, 2 frozen Day 3 (excellent quality)
    Oct18 IVF8 - Cancelled (cyst and too low TSH)
    Oct18-Jan19 bringing TSH under control
    Feb19 ERA and hysteroscopy
    Mar19 Investigation for fibroid and adenomyosis
    Apr19 adenomyosis confirmed, polyps removed
    Jun19 FET after 2 months Lupron, autoimmune protocol, transferred two day 3 frozen embryos
    Sep17 - Pergoveris 10-17 Sep, Orgalutran 15-18 Sep, Ovitrelle 18 Sep, ER 20 Sep for 2 follies, 1 mature egg, fertilized, ET 1x 2d 4-cell embryo 22/09, 05/10 BFN
    Nov17 IVF2 - Pergoveris 2-14 Nov, Orgalutran 5-14 Nov, Ovitrelle 15 Nov, ER 17 Nov for 3 follies, 1 mature egg, did not fertilize
    Jan18 IVF3 - Pergoveris 30 Dec - 8 Jan, Orgalutran 5-8 Jan, Ovitrelle 9 Jan, ER 11 Jan 3 eggs, 2 mature, 1 fertilized, ET 1x 4d 12-cell embryo 15/01, 24/01 BFN
    May/Jun18 IVF4 - Rekovelle 25-29 May, Menogon 30May - 2Jun, Zomacton 25 27 29 31 May and 2Jun, Cetrotide 30May - 3Jun, Gonasi 3Jun, ER 5Jun 4 eggs, none mature, two matured overnight, 1 fertilized with ICSI, Frozen day 3 but not good quality
    Jun/Jul18 IVF5 - Rekovelle 21-24 June, Menogon 25Jun-3Jul, Puregon 4-5Jul, Zomacton 21 23 25 27 29 Jun, Cetrotide 25Jun-5Jul, Gonasi 6Jul, ER 8Jul 5 eggs, 3 mature, 2 fertilized with ICSI, 2 frozen day 3 but not good quality
    Jul/Aug18 IVF6 - Rekovelle 26-29 Jul, Menogon 30Jul-7Aug, Buserelin 26Jul-7Aug, Zomacton 26 28 30 Jul 1 3 Aug, Gonasi 7Aug, ER 9Aug 4 eggs, 3 mature, 2 fertilized (normal IVF), 2 frozen day 3 good quality
    Sep/Oct18 IVF7 - Menogon 19-30Sep, Buserelin 19-30Sep, Zomacton 19 21 23 25 27 Sep, Ovitrelle 1 Oct, ER 3 eggs, 3 mature, 2 fertilized with ICSI, 2 frozen day 3 excellent quality 

    Fav Quote: The greatest thing you'll ever learn is just to love and be loved in return

  • @hopefuljj- Yay on another blast!! SO many prayers that there are some normals in your 4! You deserve this so much and I am rooting for you! Any idea when you will have results? I think you should start prepping for an FET assuming you will have at least one to transfer! I think I am going to watch the One More Shot movie tonight. I am glad the stories are out there, but sometimes they are hard to watch since we are living it. I do like to send them to my mom and MIL and select others to help them understand how hard this journey is.

    @emmasemm- when is your beta? I know you are already moving on to next steps, but still thinking of you on beta day since its never easy...

    AFM- lining only grew from 8.8 to 9.3 with 8 more days of estrogen, but its plenty thick for an ERA I believe. Thought it would have grown a little more since i got to 10.6mm last cycle, but i will definitely take it!! Still waiting on the official call, but I am assuming I will get the greenlight to start PIO at 7pm tonight. Then ERA would be on Wednesday. 

    History in Spoiler

    Age: 32 (same with DH). Together since 2006, Married June 2013 and TTC since August 2015
    Diagnosis: Mild Endo, DOR (AMH of 1.5), Poor Quality Eggs/embryos, Displaced Window of Implantation (ERA Post Receptive)
    March-May 2016: 1 TI and 2 IUIs- BFN 
    June 2016- Laproscopy- found/removed mild endo and confirmed only 1 normal healthy ovary.
    August 2016- IVF #1 with Antagonist Protocol- Cancelled (2 lead follies), converted to IUI- BFN
    Oct-Nov 2016- IVF #2 with Estrogen Priming Micro Lupron Protocol, 2 eggs retrieved, day 3 transfer of 1- BFN
    January 2017- New RE, IVF#3 with Estrogen Priming Antagonist Protocol, 12 eggs, 8 mature, 6 fertilized, 2 day 5 early blasts transferred (none to freeze :(), BFN
    May 2017- Sept 2017- Starting Donor Egg process! Waiting for donor to be available... and then she is pregnant at baseline :(
    Oct 2017- Donor #2: 25R, 22M,18F, 12 blasts frozen! Fresh transfer cancelled due to thin lining with fluid :(
    Nov 2017- Hysterscopy to remove polyp
    Dec 2017- DE FET #1 on 12/8 on 2 perfect blasts- BFN and devastated
    Jan-Mar 2018- ERA #1- Post receptive by 24 hours, ERA #2 RECEPTIVE with 4 days of Progesterone
    Apr 2018- DE FET cancelled for lining issues :(
    Jun 2018- DE FET #2 of two 1AA blasts- first BFP ever! Beta 10dp5dt- 378, Beta 14dp5dt- 2840, Beta 16dp5dt- 4035, beta 18dp5dt- 10916. Due on 2/20 with one baby after a vanishing twin
    Baby Born born early @ 33.5 weeks due to Pre-e
    Back for # 2!
  • @jamieh2000 that’s definitely thick enough! Fx they say you can kick off the progesterone tonight. Did they always have you start it in the evening? They make me take my first dose *exactly* 24 hours after my ER time. Which is exactly 34 hours after my trigger.

    And beta is Monday. Which will be CD5. And I’ll probably be down to only spotting. Which is like the biggest joke ever. Beta immediately after AF has stopped... got to be a new way to do it!

    But I’m all ready for the clinic review with DH tomorrow. I had one great call last night and two today - one clinic even put me through to their head embryologist who I talked to for 45 minutes!  He said if I choose their clinic I am welcome to go meet him and have a tour of we lab. And I literally grilled him so many things and at the end he even joked that with what I know he’d be happy to offer me a job hehehehe. After a crappy week I’m chalking that up as a big win!
    Me 43 DH 45
    Married 12/2016
    TTC #1 since 04/2015
    AMA, DOR (AMH 0.65, AFC 2-4) and autoimmune issues (RA, APS), low TSH, adenomyosis
    7 retrievals, 3 transfers
    Jun19 FET BFP, due date 7th March 2020, DD born Feb20
    Sep17 IVF1 - 1ER, 1F, 1ET, BFN
    Nov17 IVF2 - 1ER, 0F
    Jan18 IVF3 - 3ER, 1F, 1ET, BFN
    Feb18 - second opinion and additional testing
    Apr18 IVF4 - cancelled (E2 too high)
    May/Jun18 IVF4 - 4ER, 0M, 1F, 1 frozen day 3 (not best quality)
    Jun/Jul18 IVF5 - 5 ER, 3M, 2F, 2 frozen day 3 (not best quality)
    Jul/Aug18 IVF6 - 4ER, 3M, 2F, 2 frozen day 3 (good quality)
    Aug/Sep18 IVF7 - cancelled (cyst)
    Sep/Oct18 IVF7 - 3ER, 3M, 2F, 2 frozen Day 3 (excellent quality)
    Oct18 IVF8 - Cancelled (cyst and too low TSH)
    Oct18-Jan19 bringing TSH under control
    Feb19 ERA and hysteroscopy
    Mar19 Investigation for fibroid and adenomyosis
    Apr19 adenomyosis confirmed, polyps removed
    Jun19 FET after 2 months Lupron, autoimmune protocol, transferred two day 3 frozen embryos
    Sep17 - Pergoveris 10-17 Sep, Orgalutran 15-18 Sep, Ovitrelle 18 Sep, ER 20 Sep for 2 follies, 1 mature egg, fertilized, ET 1x 2d 4-cell embryo 22/09, 05/10 BFN
    Nov17 IVF2 - Pergoveris 2-14 Nov, Orgalutran 5-14 Nov, Ovitrelle 15 Nov, ER 17 Nov for 3 follies, 1 mature egg, did not fertilize
    Jan18 IVF3 - Pergoveris 30 Dec - 8 Jan, Orgalutran 5-8 Jan, Ovitrelle 9 Jan, ER 11 Jan 3 eggs, 2 mature, 1 fertilized, ET 1x 4d 12-cell embryo 15/01, 24/01 BFN
    May/Jun18 IVF4 - Rekovelle 25-29 May, Menogon 30May - 2Jun, Zomacton 25 27 29 31 May and 2Jun, Cetrotide 30May - 3Jun, Gonasi 3Jun, ER 5Jun 4 eggs, none mature, two matured overnight, 1 fertilized with ICSI, Frozen day 3 but not good quality
    Jun/Jul18 IVF5 - Rekovelle 21-24 June, Menogon 25Jun-3Jul, Puregon 4-5Jul, Zomacton 21 23 25 27 29 Jun, Cetrotide 25Jun-5Jul, Gonasi 6Jul, ER 8Jul 5 eggs, 3 mature, 2 fertilized with ICSI, 2 frozen day 3 but not good quality
    Jul/Aug18 IVF6 - Rekovelle 26-29 Jul, Menogon 30Jul-7Aug, Buserelin 26Jul-7Aug, Zomacton 26 28 30 Jul 1 3 Aug, Gonasi 7Aug, ER 9Aug 4 eggs, 3 mature, 2 fertilized (normal IVF), 2 frozen day 3 good quality
    Sep/Oct18 IVF7 - Menogon 19-30Sep, Buserelin 19-30Sep, Zomacton 19 21 23 25 27 Sep, Ovitrelle 1 Oct, ER 3 eggs, 3 mature, 2 fertilized with ICSI, 2 frozen day 3 excellent quality 

    Fav Quote: The greatest thing you'll ever learn is just to love and be loved in return

  • @emmasemm- Yes, they always do the evening I believe. I think its different for FETs than fresh maybe. With a fresh, the left over follicles give off progesterone right after ER. If my ERA said I need 12 more hours of progesterone, then they will know I should start at 7am 5 days before instead of 7pm 5 days before. So they just want to make sure they know exactly what I start. I don't understand why they have your beta so late! Especially if you are spotting, they should let you come in. But I also feel like the supplemental progesterone should have been enough to keep your period away? Sounds like you are finding some great clinics! Are they all in EU? Once you pick one, I can't wait to hear about it. Will you still have a follow up with your current RE?
    History in Spoiler

    Age: 32 (same with DH). Together since 2006, Married June 2013 and TTC since August 2015
    Diagnosis: Mild Endo, DOR (AMH of 1.5), Poor Quality Eggs/embryos, Displaced Window of Implantation (ERA Post Receptive)
    March-May 2016: 1 TI and 2 IUIs- BFN 
    June 2016- Laproscopy- found/removed mild endo and confirmed only 1 normal healthy ovary.
    August 2016- IVF #1 with Antagonist Protocol- Cancelled (2 lead follies), converted to IUI- BFN
    Oct-Nov 2016- IVF #2 with Estrogen Priming Micro Lupron Protocol, 2 eggs retrieved, day 3 transfer of 1- BFN
    January 2017- New RE, IVF#3 with Estrogen Priming Antagonist Protocol, 12 eggs, 8 mature, 6 fertilized, 2 day 5 early blasts transferred (none to freeze :(), BFN
    May 2017- Sept 2017- Starting Donor Egg process! Waiting for donor to be available... and then she is pregnant at baseline :(
    Oct 2017- Donor #2: 25R, 22M,18F, 12 blasts frozen! Fresh transfer cancelled due to thin lining with fluid :(
    Nov 2017- Hysterscopy to remove polyp
    Dec 2017- DE FET #1 on 12/8 on 2 perfect blasts- BFN and devastated
    Jan-Mar 2018- ERA #1- Post receptive by 24 hours, ERA #2 RECEPTIVE with 4 days of Progesterone
    Apr 2018- DE FET cancelled for lining issues :(
    Jun 2018- DE FET #2 of two 1AA blasts- first BFP ever! Beta 10dp5dt- 378, Beta 14dp5dt- 2840, Beta 16dp5dt- 4035, beta 18dp5dt- 10916. Due on 2/20 with one baby after a vanishing twin
    Baby Born born early @ 33.5 weeks due to Pre-e
    Back for # 2!
  • @emmasemm I’m so happy to hear you are having some great calls:)    I did get the abnormalities for those embryos.

    I had two D5 embryos with perfect grades (AA) and the 3rd was a D6 embryo (BB).
    The BB was missing a copy of chromosome 6.
    And one AA had a duplication of chromosome 11 and the other Loss of chromosome 21


    @JamieH2000  did you watch it?? I kinda want to make DH watch it too... but then I would have to watch it again.  

    Me: Hashimoto Autoimune Disease
    Homozygous MTHFR Cr677
    DOR - AMH  .27 High FSH (don't even know how high)
    2 iui's to start - BFN 
    IVF 1 -3 made it do day 5!    2 5AA 1 6BB  PGS results =  all abnormal :(
    IVF 2 - stimmed for 19 days. insanity. Had 5 follicles that looked mature but only 2 contained mature eggs the others were empty.  Nothing made it to day 5
    IVF 3 - added in HGH - 4 mature follicles (had some empties again) 3 made it to day 5/6 for PGS (held for testing with next retrieval
    IVF 4 - Upped my dosage for the first time - Canceled 11 days into sims - looked like 1 follicle and we were afraid it was empty
    IVF 5 - Canceled -  looked like 1 follicle and we were afraid it was empty
    IVF 6 - 3 mature, 2 fertalized 1 made it to day 5 and sent for PGS

    Sent in IVF round 3 and 6 (4 embryos) for PGS testing and got 2 normal embryos!!!  1Boy and 1Girl. Took a little over a year to get those two embryos so demanded all sorts of test prior to attempting transfer. Did EFT, ERA and NK Cells testing.

    FET#1 - Intralipid drips, Prednisone, and did a depot lupron shot before starting the FET protocol
    Chemical pregnancy
    FET#2 - PGS normal boy - BFN
    Natural pregnancy - cycle following the FET2????   Miscarriage at 8 weeks.  viability scan had shown an enlarged yolk sac so I had been warned that it was likely not chromosonally normal :(

    DEIVF cycle - picked a donor who is willing to be open! Her cycle resulted in in 4 PGS Normal embryos
    1st transfer - chemical pregnancy
    2nd transfer - success, May 17 2020 due date!
  • @jamieh2000 I don’t understand why my beta is so late either. Except I am wondering if they try to avoid giving hope with the very low beta numbers, which would mostly be below the threshold for positive if you leave it longer... and that’s some ladies maybe don’t go for betas if they have AF already...

    I had asked my RE about how could I get AF whilst still on progesterone back after the September failure. He said it didn’t work like that. We had an “animated discussion” about it (in German). His opinion was that there is more than the progesterone level alone which stops AF from starting (ie the lining to start to break down). Which I guess is true, that it’s not progesterone alone - but my argument to him was that it was one of the dominating driving factors.
    But this time I was on Estrogen as well after ET. So I was really surprised AF came whilst I was still on the meds.
    Also as provera which is used to make AF come in people who have had an an-O cycle or where they had no AF for a long time supposedly works by giving you a really high boost in progesterone level for a few days, which when it drops suddenly triggers your lining to break down and AF to start, then I don’t understand how that could work if my RE is right... 
    Some days I am really really thinking about going back and studying endocrinology at university as there is just so much mis-information out there it’s like wading through treacle.

    @hopefuljj sorry they have those issues. FX for the ones you’ve just sent for testing!
    But on the other hand the deletions are really interesting to me. Did they confirm they were complete or partial deletions? Did they have you go through them with a genetic counselor? An extra part of 11 and deletions on 21 seem to be not life compatible, so if they’re not sure if all cells are affected or not they might agree to you transferring them (if you wanted) as if they’re not ok they will just not develop further. But partial deletions on 6 has a very wide spectrum of possibilities depending on where the exact deletions are. Seems some people don’t know they have partial deletions on 6 until they have a child with more complex deletions... and also quite a difference between deletions on the p or q copy. So if it’s only a partial deletion you might want to know more about which parts before deciding (if you come to that point, which hopefully you won’t).
    I actual did a first year of genetics back 20 years ago (so what I learnt is very very out of date) - so if I don’t take endocrinology as a second career, maybe I could go back to genetics!

    Oh and I watched the movie too. I thought it was very well done. I’ve suggested to DH he watch it, but I think he would need to watch it on his own, in his own time.
    Me 43 DH 45
    Married 12/2016
    TTC #1 since 04/2015
    AMA, DOR (AMH 0.65, AFC 2-4) and autoimmune issues (RA, APS), low TSH, adenomyosis
    7 retrievals, 3 transfers
    Jun19 FET BFP, due date 7th March 2020, DD born Feb20
    Sep17 IVF1 - 1ER, 1F, 1ET, BFN
    Nov17 IVF2 - 1ER, 0F
    Jan18 IVF3 - 3ER, 1F, 1ET, BFN
    Feb18 - second opinion and additional testing
    Apr18 IVF4 - cancelled (E2 too high)
    May/Jun18 IVF4 - 4ER, 0M, 1F, 1 frozen day 3 (not best quality)
    Jun/Jul18 IVF5 - 5 ER, 3M, 2F, 2 frozen day 3 (not best quality)
    Jul/Aug18 IVF6 - 4ER, 3M, 2F, 2 frozen day 3 (good quality)
    Aug/Sep18 IVF7 - cancelled (cyst)
    Sep/Oct18 IVF7 - 3ER, 3M, 2F, 2 frozen Day 3 (excellent quality)
    Oct18 IVF8 - Cancelled (cyst and too low TSH)
    Oct18-Jan19 bringing TSH under control
    Feb19 ERA and hysteroscopy
    Mar19 Investigation for fibroid and adenomyosis
    Apr19 adenomyosis confirmed, polyps removed
    Jun19 FET after 2 months Lupron, autoimmune protocol, transferred two day 3 frozen embryos
    Sep17 - Pergoveris 10-17 Sep, Orgalutran 15-18 Sep, Ovitrelle 18 Sep, ER 20 Sep for 2 follies, 1 mature egg, fertilized, ET 1x 2d 4-cell embryo 22/09, 05/10 BFN
    Nov17 IVF2 - Pergoveris 2-14 Nov, Orgalutran 5-14 Nov, Ovitrelle 15 Nov, ER 17 Nov for 3 follies, 1 mature egg, did not fertilize
    Jan18 IVF3 - Pergoveris 30 Dec - 8 Jan, Orgalutran 5-8 Jan, Ovitrelle 9 Jan, ER 11 Jan 3 eggs, 2 mature, 1 fertilized, ET 1x 4d 12-cell embryo 15/01, 24/01 BFN
    May/Jun18 IVF4 - Rekovelle 25-29 May, Menogon 30May - 2Jun, Zomacton 25 27 29 31 May and 2Jun, Cetrotide 30May - 3Jun, Gonasi 3Jun, ER 5Jun 4 eggs, none mature, two matured overnight, 1 fertilized with ICSI, Frozen day 3 but not good quality
    Jun/Jul18 IVF5 - Rekovelle 21-24 June, Menogon 25Jun-3Jul, Puregon 4-5Jul, Zomacton 21 23 25 27 29 Jun, Cetrotide 25Jun-5Jul, Gonasi 6Jul, ER 8Jul 5 eggs, 3 mature, 2 fertilized with ICSI, 2 frozen day 3 but not good quality
    Jul/Aug18 IVF6 - Rekovelle 26-29 Jul, Menogon 30Jul-7Aug, Buserelin 26Jul-7Aug, Zomacton 26 28 30 Jul 1 3 Aug, Gonasi 7Aug, ER 9Aug 4 eggs, 3 mature, 2 fertilized (normal IVF), 2 frozen day 3 good quality
    Sep/Oct18 IVF7 - Menogon 19-30Sep, Buserelin 19-30Sep, Zomacton 19 21 23 25 27 Sep, Ovitrelle 1 Oct, ER 3 eggs, 3 mature, 2 fertilized with ICSI, 2 frozen day 3 excellent quality 

    Fav Quote: The greatest thing you'll ever learn is just to love and be loved in return

  • Thanks for the info @emmasemm!! I tried to set up a consult with a geneticist at the lab who did the testing and ended up not being able to work out a time that worked due to a crazy work schedule and just dropped it.  I was originally freaking out that my clinic won’t transfer them but paid to keep them on ice where they still remain because they were ok to not discard them even though that’s what you agree to before you begin:-/ it took me maaaaany months to even get anything else on ice so the cost seemed a little crazy but I couldn’t let them discard.  Depending on what happens this time I’ll decide how to proceed.  
    You would make an amazing endocrinologist or geneticist:).   And I agree, the movie was SO well done.  Really beautiful.  Very hard to watch and to not think about now that it’s over but great.  DH doesn’t want to watch it unless I watch it with him.  I knew I would not be able to watch it with him the first time which is why I watched/sobbed in private.  I’m a bit of an odd ball with showing my vulnerabilities even to DH:-/ but I think I could watch it again now that I know the outcome. 
    Me: Hashimoto Autoimune Disease
    Homozygous MTHFR Cr677
    DOR - AMH  .27 High FSH (don't even know how high)
    2 iui's to start - BFN 
    IVF 1 -3 made it do day 5!    2 5AA 1 6BB  PGS results =  all abnormal :(
    IVF 2 - stimmed for 19 days. insanity. Had 5 follicles that looked mature but only 2 contained mature eggs the others were empty.  Nothing made it to day 5
    IVF 3 - added in HGH - 4 mature follicles (had some empties again) 3 made it to day 5/6 for PGS (held for testing with next retrieval
    IVF 4 - Upped my dosage for the first time - Canceled 11 days into sims - looked like 1 follicle and we were afraid it was empty
    IVF 5 - Canceled -  looked like 1 follicle and we were afraid it was empty
    IVF 6 - 3 mature, 2 fertalized 1 made it to day 5 and sent for PGS

    Sent in IVF round 3 and 6 (4 embryos) for PGS testing and got 2 normal embryos!!!  1Boy and 1Girl. Took a little over a year to get those two embryos so demanded all sorts of test prior to attempting transfer. Did EFT, ERA and NK Cells testing.

    FET#1 - Intralipid drips, Prednisone, and did a depot lupron shot before starting the FET protocol
    Chemical pregnancy
    FET#2 - PGS normal boy - BFN
    Natural pregnancy - cycle following the FET2????   Miscarriage at 8 weeks.  viability scan had shown an enlarged yolk sac so I had been warned that it was likely not chromosonally normal :(

    DEIVF cycle - picked a donor who is willing to be open! Her cycle resulted in in 4 PGS Normal embryos
    1st transfer - chemical pregnancy
    2nd transfer - success, May 17 2020 due date!
  • @emmasemm- If you were on both estrogen and progesterone after your transfer, I am struggling to understand how AF came. What type of progesterone are you on? Maybe you aren't absorbing it somehow? For your next trasnfer, I would maybe request your levels checked during the tww? I also think you could be an RE! I do think it would be a very rewarding career!

    @hopefuljj- me and DH did watch the movie and it was very well done. It does really hit close to home for anyone with DOR and/or pursuing donor options. I recommended it to my mom. I wish I could share it on facebook and be like THIS is what we are going through. We have been videoing our journey too, and plan to make a shorter annoucement video if that day comes. 
    History in Spoiler

    Age: 32 (same with DH). Together since 2006, Married June 2013 and TTC since August 2015
    Diagnosis: Mild Endo, DOR (AMH of 1.5), Poor Quality Eggs/embryos, Displaced Window of Implantation (ERA Post Receptive)
    March-May 2016: 1 TI and 2 IUIs- BFN 
    June 2016- Laproscopy- found/removed mild endo and confirmed only 1 normal healthy ovary.
    August 2016- IVF #1 with Antagonist Protocol- Cancelled (2 lead follies), converted to IUI- BFN
    Oct-Nov 2016- IVF #2 with Estrogen Priming Micro Lupron Protocol, 2 eggs retrieved, day 3 transfer of 1- BFN
    January 2017- New RE, IVF#3 with Estrogen Priming Antagonist Protocol, 12 eggs, 8 mature, 6 fertilized, 2 day 5 early blasts transferred (none to freeze :(), BFN
    May 2017- Sept 2017- Starting Donor Egg process! Waiting for donor to be available... and then she is pregnant at baseline :(
    Oct 2017- Donor #2: 25R, 22M,18F, 12 blasts frozen! Fresh transfer cancelled due to thin lining with fluid :(
    Nov 2017- Hysterscopy to remove polyp
    Dec 2017- DE FET #1 on 12/8 on 2 perfect blasts- BFN and devastated
    Jan-Mar 2018- ERA #1- Post receptive by 24 hours, ERA #2 RECEPTIVE with 4 days of Progesterone
    Apr 2018- DE FET cancelled for lining issues :(
    Jun 2018- DE FET #2 of two 1AA blasts- first BFP ever! Beta 10dp5dt- 378, Beta 14dp5dt- 2840, Beta 16dp5dt- 4035, beta 18dp5dt- 10916. Due on 2/20 with one baby after a vanishing twin
    Baby Born born early @ 33.5 weeks due to Pre-e
    Back for # 2!
  • @jamieh2000 I know right??? I was on crinone and estrafim tablets. And the dosages I’m on are the standard on all their printed fresh transfer info sheets, and he confirmed last time I asked about the dosages and that they don’t do PIO. I guess it could be that I wasn’t absorbing the crinone. But as crinone is not getting to my endometrium via the blood, blood tests to check progesterone levels would have been pretty useless. And I definitely had all the progesterone side effects!!!
    We decided today if they call us in for a WTF appointment then I will go on my own (as DH is on a different insurance he has to self pay for the consultation if he attends, and since we won’t use them again we said no point coming this time). First I will do the “most pointless beta in the world ever” Monday morning, wait for them to call with the result in the afternoon and see if they say we have to go to the WTF appointment. If not I need them to send me the records from this cycle.
    As this morning we picked our next steps - and for that I need all my latest records!
    I do have to say DH is really my rock through all of this. When we got married a year ago we definitely didn’t bargain on going overseas for medical treatment... 

    How’s your PIO going?

    @hopefuljj when do you expect your PGS results back?
    Me 43 DH 45
    Married 12/2016
    TTC #1 since 04/2015
    AMA, DOR (AMH 0.65, AFC 2-4) and autoimmune issues (RA, APS), low TSH, adenomyosis
    7 retrievals, 3 transfers
    Jun19 FET BFP, due date 7th March 2020, DD born Feb20
    Sep17 IVF1 - 1ER, 1F, 1ET, BFN
    Nov17 IVF2 - 1ER, 0F
    Jan18 IVF3 - 3ER, 1F, 1ET, BFN
    Feb18 - second opinion and additional testing
    Apr18 IVF4 - cancelled (E2 too high)
    May/Jun18 IVF4 - 4ER, 0M, 1F, 1 frozen day 3 (not best quality)
    Jun/Jul18 IVF5 - 5 ER, 3M, 2F, 2 frozen day 3 (not best quality)
    Jul/Aug18 IVF6 - 4ER, 3M, 2F, 2 frozen day 3 (good quality)
    Aug/Sep18 IVF7 - cancelled (cyst)
    Sep/Oct18 IVF7 - 3ER, 3M, 2F, 2 frozen Day 3 (excellent quality)
    Oct18 IVF8 - Cancelled (cyst and too low TSH)
    Oct18-Jan19 bringing TSH under control
    Feb19 ERA and hysteroscopy
    Mar19 Investigation for fibroid and adenomyosis
    Apr19 adenomyosis confirmed, polyps removed
    Jun19 FET after 2 months Lupron, autoimmune protocol, transferred two day 3 frozen embryos
    Sep17 - Pergoveris 10-17 Sep, Orgalutran 15-18 Sep, Ovitrelle 18 Sep, ER 20 Sep for 2 follies, 1 mature egg, fertilized, ET 1x 2d 4-cell embryo 22/09, 05/10 BFN
    Nov17 IVF2 - Pergoveris 2-14 Nov, Orgalutran 5-14 Nov, Ovitrelle 15 Nov, ER 17 Nov for 3 follies, 1 mature egg, did not fertilize
    Jan18 IVF3 - Pergoveris 30 Dec - 8 Jan, Orgalutran 5-8 Jan, Ovitrelle 9 Jan, ER 11 Jan 3 eggs, 2 mature, 1 fertilized, ET 1x 4d 12-cell embryo 15/01, 24/01 BFN
    May/Jun18 IVF4 - Rekovelle 25-29 May, Menogon 30May - 2Jun, Zomacton 25 27 29 31 May and 2Jun, Cetrotide 30May - 3Jun, Gonasi 3Jun, ER 5Jun 4 eggs, none mature, two matured overnight, 1 fertilized with ICSI, Frozen day 3 but not good quality
    Jun/Jul18 IVF5 - Rekovelle 21-24 June, Menogon 25Jun-3Jul, Puregon 4-5Jul, Zomacton 21 23 25 27 29 Jun, Cetrotide 25Jun-5Jul, Gonasi 6Jul, ER 8Jul 5 eggs, 3 mature, 2 fertilized with ICSI, 2 frozen day 3 but not good quality
    Jul/Aug18 IVF6 - Rekovelle 26-29 Jul, Menogon 30Jul-7Aug, Buserelin 26Jul-7Aug, Zomacton 26 28 30 Jul 1 3 Aug, Gonasi 7Aug, ER 9Aug 4 eggs, 3 mature, 2 fertilized (normal IVF), 2 frozen day 3 good quality
    Sep/Oct18 IVF7 - Menogon 19-30Sep, Buserelin 19-30Sep, Zomacton 19 21 23 25 27 Sep, Ovitrelle 1 Oct, ER 3 eggs, 3 mature, 2 fertilized with ICSI, 2 frozen day 3 excellent quality 

    Fav Quote: The greatest thing you'll ever learn is just to love and be loved in return

  • So, I went in for my baseline today.  Had a great AFC of 4, nice FSH but estrogen is high at 150.  They can’t go on with this cycle.  Ughh so frustrated, sad and broken.  It’s always something or the other  :s
  • adc0417  ugh so sorry this process is so frustrating!  Can they just wait for your estrogen to go down and then start?  Do they see a left over follicle thats making the estrogen?

    @emmasemm I thought I missed a post that said AF showed...and i'm so confused how.  Usually crinone absorbs well into the body..I'd like to have thought it was implantation spotting.  I can't believe you're charged twice for who attends a dr appt.  Thats a new one for me!  I'm glad you're ready for next steps and hope someone new will bring better results for you.  I'm glad your DH is so supportive its important!!
    I love how knowledgeable you are!  You make me want to go and see what my abnormal embabies came back with.  All of them were missing a gene or had an extra of one none said mosaic.  And I thought they use the term mosiac for results that aren't necessarily accurately. 

    @hopefuljj I kept checking in for your update and then missed it... yay for another embaby!!  I'm excited and a basket case all at the same time for you!  I really would love for you to have done a fresh transfer too!  With all the different testing its hard to have faith in the process!  Praying you get normies back and we can move on to an FET!!!

    @jamieh2000 good luck with the ERA lining sounds good!  Mine didn't grow that much after over a week of meds so try not to stress.  PLease make sure they numb you correctly for the procedure.  I hear some horrow stories that they dont use much meds so just make sure they do!!


    History of TTC in spoiler box
    TTC since 2014
    Unexplained Infertility - but I am 40...Low AMH .30
    7 - IUI (50mg-150mg Clomid) Feb - August 2016 all BFN 
    IVF#1 August 2016 (Antagonist protocol 4/5 eggs) Cancelled cycle :( RE thought I would get at least 10.
    IVF#2 Sept 2016 (microdose luporn pro - disappearing follies, ONLY ONE, convert to IUI) BFN
    IVF#3 November 2016 (4 ER, 3 F,  3DT)-BFP  with TWINS // MC both at almost 10wks  :'( 
    IVF#4 March 2017 //EPP  (10 ER (1 wonky so 9 ER) 7F, 3B (5AB, (2)5BB) PGS tested- ALL abnormal  :'( 
    IVF#5 April 2017 // EPP (7 ER, 7F yes! 6B) 2/5 day 4/6 day - 2 PGS normal! yes!! :)
    IVF#6 May 2017 // Antagonist didn't have time for Estrogen Priming...(4 ER, 3 F, 3B) (5AB, (2) 5BB) 2 PGS normal, yes!! :)
    IVF#7 June 2017 // EPP praying this is it and then on to an FET!

  • @hopeful_mom- Unfortunately there is no numbing for ERAs at my place. My RE said its not too bad, we will see. I just remind myself the phsycial pain is very temporary and its nothing compared to a BFN.

    @adc0417- I'm so sorry girl. Did they find a cyst that is producing estrogen? I have one for 2 cycles and it was the most frustrating thing. FX it resolves itself soon!
    History in Spoiler

    Age: 32 (same with DH). Together since 2006, Married June 2013 and TTC since August 2015
    Diagnosis: Mild Endo, DOR (AMH of 1.5), Poor Quality Eggs/embryos, Displaced Window of Implantation (ERA Post Receptive)
    March-May 2016: 1 TI and 2 IUIs- BFN 
    June 2016- Laproscopy- found/removed mild endo and confirmed only 1 normal healthy ovary.
    August 2016- IVF #1 with Antagonist Protocol- Cancelled (2 lead follies), converted to IUI- BFN
    Oct-Nov 2016- IVF #2 with Estrogen Priming Micro Lupron Protocol, 2 eggs retrieved, day 3 transfer of 1- BFN
    January 2017- New RE, IVF#3 with Estrogen Priming Antagonist Protocol, 12 eggs, 8 mature, 6 fertilized, 2 day 5 early blasts transferred (none to freeze :(), BFN
    May 2017- Sept 2017- Starting Donor Egg process! Waiting for donor to be available... and then she is pregnant at baseline :(
    Oct 2017- Donor #2: 25R, 22M,18F, 12 blasts frozen! Fresh transfer cancelled due to thin lining with fluid :(
    Nov 2017- Hysterscopy to remove polyp
    Dec 2017- DE FET #1 on 12/8 on 2 perfect blasts- BFN and devastated
    Jan-Mar 2018- ERA #1- Post receptive by 24 hours, ERA #2 RECEPTIVE with 4 days of Progesterone
    Apr 2018- DE FET cancelled for lining issues :(
    Jun 2018- DE FET #2 of two 1AA blasts- first BFP ever! Beta 10dp5dt- 378, Beta 14dp5dt- 2840, Beta 16dp5dt- 4035, beta 18dp5dt- 10916. Due on 2/20 with one baby after a vanishing twin
    Baby Born born early @ 33.5 weeks due to Pre-e
    Back for # 2!
  • @JamieH2000 @Hopeful_mom No they can’t find a reason why my estrogen is high.  There are no cysts and no left over follicles.  They’re just calling it a dysfunctional cycle.  I even questioned the doc if there was a possibility of the mock estrogen cycle causing this lingering estrogen in my system and he doesn’t think so.  
    DH and I watched “One More Shot” last night and just broke down crying after.  It’s truly a painful journey of DOR/infertility.  I could relate to all emotions including the obsessiveness.  
  • @JamieH2000 i'm cringing reading your update - you can't be serious!  Best of luck!  Really hope its pain free for you!!

    @adc0417 ugh so frustrating to not have answers...hoping this is just a fluke.  My first IUI way back when I had to delay due to the same thing and because I was so distraught they kept checking my levels and then let me continue on once it resolved...I can tell you that it wasn't a successful cycle and I should've just waited for the next cycle.
    History of TTC in spoiler box
    TTC since 2014
    Unexplained Infertility - but I am 40...Low AMH .30
    7 - IUI (50mg-150mg Clomid) Feb - August 2016 all BFN 
    IVF#1 August 2016 (Antagonist protocol 4/5 eggs) Cancelled cycle :( RE thought I would get at least 10.
    IVF#2 Sept 2016 (microdose luporn pro - disappearing follies, ONLY ONE, convert to IUI) BFN
    IVF#3 November 2016 (4 ER, 3 F,  3DT)-BFP  with TWINS // MC both at almost 10wks  :'( 
    IVF#4 March 2017 //EPP  (10 ER (1 wonky so 9 ER) 7F, 3B (5AB, (2)5BB) PGS tested- ALL abnormal  :'( 
    IVF#5 April 2017 // EPP (7 ER, 7F yes! 6B) 2/5 day 4/6 day - 2 PGS normal! yes!! :)
    IVF#6 May 2017 // Antagonist didn't have time for Estrogen Priming...(4 ER, 3 F, 3B) (5AB, (2) 5BB) 2 PGS normal, yes!! :)
    IVF#7 June 2017 // EPP praying this is it and then on to an FET!

  • I just watched the documentary "One More Shot" that you've all been speaking of. Wow. It brought back a ton of (relatable) raw emotions. I love the message it relayed about how you can achieve a family, someway, somehow, it just depends on how you choose to look at it and don't let it define you. Sending you all big hugs tonight.  <3
    ****Siggy TW****
    natural pregnancy: 2008 
    Me: 28 (Hypothyroid), DH: 35
    Together since: 2010
    Married: 2013
    TTC: 2013
    Infertility: severe MFI, low AMH (0.5)
    Met RE: January 2016
    ER: 3/14 (4 follies, 6 eggs retrieved, 2 fertilized)
    fresh 3dt of 2 embryos= BFP (1 implanted)
    EDD w/ baby boy= 12/6/16
  • @adc0417- that is so frustrating! Anything you can do? like BC for 2 weeks or something? or do they just want your body to naturally cycle through it? Delays are the worst :(

    @capps42613- I agree with you! I am glad they were brave enough to share their story and such raw emotions. Its such an accurate representation. I wish it would be more mainstream and more people would watch it!

    AFM- ERA is today and I'm trying not to stress about the pain! I can do anything for 30 seconds right?!
    History in Spoiler

    Age: 32 (same with DH). Together since 2006, Married June 2013 and TTC since August 2015
    Diagnosis: Mild Endo, DOR (AMH of 1.5), Poor Quality Eggs/embryos, Displaced Window of Implantation (ERA Post Receptive)
    March-May 2016: 1 TI and 2 IUIs- BFN 
    June 2016- Laproscopy- found/removed mild endo and confirmed only 1 normal healthy ovary.
    August 2016- IVF #1 with Antagonist Protocol- Cancelled (2 lead follies), converted to IUI- BFN
    Oct-Nov 2016- IVF #2 with Estrogen Priming Micro Lupron Protocol, 2 eggs retrieved, day 3 transfer of 1- BFN
    January 2017- New RE, IVF#3 with Estrogen Priming Antagonist Protocol, 12 eggs, 8 mature, 6 fertilized, 2 day 5 early blasts transferred (none to freeze :(), BFN
    May 2017- Sept 2017- Starting Donor Egg process! Waiting for donor to be available... and then she is pregnant at baseline :(
    Oct 2017- Donor #2: 25R, 22M,18F, 12 blasts frozen! Fresh transfer cancelled due to thin lining with fluid :(
    Nov 2017- Hysterscopy to remove polyp
    Dec 2017- DE FET #1 on 12/8 on 2 perfect blasts- BFN and devastated
    Jan-Mar 2018- ERA #1- Post receptive by 24 hours, ERA #2 RECEPTIVE with 4 days of Progesterone
    Apr 2018- DE FET cancelled for lining issues :(
    Jun 2018- DE FET #2 of two 1AA blasts- first BFP ever! Beta 10dp5dt- 378, Beta 14dp5dt- 2840, Beta 16dp5dt- 4035, beta 18dp5dt- 10916. Due on 2/20 with one baby after a vanishing twin
    Baby Born born early @ 33.5 weeks due to Pre-e
    Back for # 2!
  • @JamieH2000 hoping its over and you're home resting!!
    History of TTC in spoiler box
    TTC since 2014
    Unexplained Infertility - but I am 40...Low AMH .30
    7 - IUI (50mg-150mg Clomid) Feb - August 2016 all BFN 
    IVF#1 August 2016 (Antagonist protocol 4/5 eggs) Cancelled cycle :( RE thought I would get at least 10.
    IVF#2 Sept 2016 (microdose luporn pro - disappearing follies, ONLY ONE, convert to IUI) BFN
    IVF#3 November 2016 (4 ER, 3 F,  3DT)-BFP  with TWINS // MC both at almost 10wks  :'( 
    IVF#4 March 2017 //EPP  (10 ER (1 wonky so 9 ER) 7F, 3B (5AB, (2)5BB) PGS tested- ALL abnormal  :'( 
    IVF#5 April 2017 // EPP (7 ER, 7F yes! 6B) 2/5 day 4/6 day - 2 PGS normal! yes!! :)
    IVF#6 May 2017 // Antagonist didn't have time for Estrogen Priming...(4 ER, 3 F, 3B) (5AB, (2) 5BB) 2 PGS normal, yes!! :)
    IVF#7 June 2017 // EPP praying this is it and then on to an FET!

  • @jamieh2000 hoping it went smoothly!
    Me 43 DH 45
    Married 12/2016
    TTC #1 since 04/2015
    AMA, DOR (AMH 0.65, AFC 2-4) and autoimmune issues (RA, APS), low TSH, adenomyosis
    7 retrievals, 3 transfers
    Jun19 FET BFP, due date 7th March 2020, DD born Feb20
    Sep17 IVF1 - 1ER, 1F, 1ET, BFN
    Nov17 IVF2 - 1ER, 0F
    Jan18 IVF3 - 3ER, 1F, 1ET, BFN
    Feb18 - second opinion and additional testing
    Apr18 IVF4 - cancelled (E2 too high)
    May/Jun18 IVF4 - 4ER, 0M, 1F, 1 frozen day 3 (not best quality)
    Jun/Jul18 IVF5 - 5 ER, 3M, 2F, 2 frozen day 3 (not best quality)
    Jul/Aug18 IVF6 - 4ER, 3M, 2F, 2 frozen day 3 (good quality)
    Aug/Sep18 IVF7 - cancelled (cyst)
    Sep/Oct18 IVF7 - 3ER, 3M, 2F, 2 frozen Day 3 (excellent quality)
    Oct18 IVF8 - Cancelled (cyst and too low TSH)
    Oct18-Jan19 bringing TSH under control
    Feb19 ERA and hysteroscopy
    Mar19 Investigation for fibroid and adenomyosis
    Apr19 adenomyosis confirmed, polyps removed
    Jun19 FET after 2 months Lupron, autoimmune protocol, transferred two day 3 frozen embryos
    Sep17 - Pergoveris 10-17 Sep, Orgalutran 15-18 Sep, Ovitrelle 18 Sep, ER 20 Sep for 2 follies, 1 mature egg, fertilized, ET 1x 2d 4-cell embryo 22/09, 05/10 BFN
    Nov17 IVF2 - Pergoveris 2-14 Nov, Orgalutran 5-14 Nov, Ovitrelle 15 Nov, ER 17 Nov for 3 follies, 1 mature egg, did not fertilize
    Jan18 IVF3 - Pergoveris 30 Dec - 8 Jan, Orgalutran 5-8 Jan, Ovitrelle 9 Jan, ER 11 Jan 3 eggs, 2 mature, 1 fertilized, ET 1x 4d 12-cell embryo 15/01, 24/01 BFN
    May/Jun18 IVF4 - Rekovelle 25-29 May, Menogon 30May - 2Jun, Zomacton 25 27 29 31 May and 2Jun, Cetrotide 30May - 3Jun, Gonasi 3Jun, ER 5Jun 4 eggs, none mature, two matured overnight, 1 fertilized with ICSI, Frozen day 3 but not good quality
    Jun/Jul18 IVF5 - Rekovelle 21-24 June, Menogon 25Jun-3Jul, Puregon 4-5Jul, Zomacton 21 23 25 27 29 Jun, Cetrotide 25Jun-5Jul, Gonasi 6Jul, ER 8Jul 5 eggs, 3 mature, 2 fertilized with ICSI, 2 frozen day 3 but not good quality
    Jul/Aug18 IVF6 - Rekovelle 26-29 Jul, Menogon 30Jul-7Aug, Buserelin 26Jul-7Aug, Zomacton 26 28 30 Jul 1 3 Aug, Gonasi 7Aug, ER 9Aug 4 eggs, 3 mature, 2 fertilized (normal IVF), 2 frozen day 3 good quality
    Sep/Oct18 IVF7 - Menogon 19-30Sep, Buserelin 19-30Sep, Zomacton 19 21 23 25 27 Sep, Ovitrelle 1 Oct, ER 3 eggs, 3 mature, 2 fertilized with ICSI, 2 frozen day 3 excellent quality 

    Fav Quote: The greatest thing you'll ever learn is just to love and be loved in return

  • @jamieh2000 so pleased you have that done! Fx for good results and transfer in March!

    AFM first second consult tomorrow evening. Was super excited, but now we have a legal issue to deal with which is taking quite a lot of time and energy. It never rains but it pours...
    Will let you now how it goes tomorrow though!
    Me 43 DH 45
    Married 12/2016
    TTC #1 since 04/2015
    AMA, DOR (AMH 0.65, AFC 2-4) and autoimmune issues (RA, APS), low TSH, adenomyosis
    7 retrievals, 3 transfers
    Jun19 FET BFP, due date 7th March 2020, DD born Feb20
    Sep17 IVF1 - 1ER, 1F, 1ET, BFN
    Nov17 IVF2 - 1ER, 0F
    Jan18 IVF3 - 3ER, 1F, 1ET, BFN
    Feb18 - second opinion and additional testing
    Apr18 IVF4 - cancelled (E2 too high)
    May/Jun18 IVF4 - 4ER, 0M, 1F, 1 frozen day 3 (not best quality)
    Jun/Jul18 IVF5 - 5 ER, 3M, 2F, 2 frozen day 3 (not best quality)
    Jul/Aug18 IVF6 - 4ER, 3M, 2F, 2 frozen day 3 (good quality)
    Aug/Sep18 IVF7 - cancelled (cyst)
    Sep/Oct18 IVF7 - 3ER, 3M, 2F, 2 frozen Day 3 (excellent quality)
    Oct18 IVF8 - Cancelled (cyst and too low TSH)
    Oct18-Jan19 bringing TSH under control
    Feb19 ERA and hysteroscopy
    Mar19 Investigation for fibroid and adenomyosis
    Apr19 adenomyosis confirmed, polyps removed
    Jun19 FET after 2 months Lupron, autoimmune protocol, transferred two day 3 frozen embryos
    Sep17 - Pergoveris 10-17 Sep, Orgalutran 15-18 Sep, Ovitrelle 18 Sep, ER 20 Sep for 2 follies, 1 mature egg, fertilized, ET 1x 2d 4-cell embryo 22/09, 05/10 BFN
    Nov17 IVF2 - Pergoveris 2-14 Nov, Orgalutran 5-14 Nov, Ovitrelle 15 Nov, ER 17 Nov for 3 follies, 1 mature egg, did not fertilize
    Jan18 IVF3 - Pergoveris 30 Dec - 8 Jan, Orgalutran 5-8 Jan, Ovitrelle 9 Jan, ER 11 Jan 3 eggs, 2 mature, 1 fertilized, ET 1x 4d 12-cell embryo 15/01, 24/01 BFN
    May/Jun18 IVF4 - Rekovelle 25-29 May, Menogon 30May - 2Jun, Zomacton 25 27 29 31 May and 2Jun, Cetrotide 30May - 3Jun, Gonasi 3Jun, ER 5Jun 4 eggs, none mature, two matured overnight, 1 fertilized with ICSI, Frozen day 3 but not good quality
    Jun/Jul18 IVF5 - Rekovelle 21-24 June, Menogon 25Jun-3Jul, Puregon 4-5Jul, Zomacton 21 23 25 27 29 Jun, Cetrotide 25Jun-5Jul, Gonasi 6Jul, ER 8Jul 5 eggs, 3 mature, 2 fertilized with ICSI, 2 frozen day 3 but not good quality
    Jul/Aug18 IVF6 - Rekovelle 26-29 Jul, Menogon 30Jul-7Aug, Buserelin 26Jul-7Aug, Zomacton 26 28 30 Jul 1 3 Aug, Gonasi 7Aug, ER 9Aug 4 eggs, 3 mature, 2 fertilized (normal IVF), 2 frozen day 3 good quality
    Sep/Oct18 IVF7 - Menogon 19-30Sep, Buserelin 19-30Sep, Zomacton 19 21 23 25 27 Sep, Ovitrelle 1 Oct, ER 3 eggs, 3 mature, 2 fertilized with ICSI, 2 frozen day 3 excellent quality 

    Fav Quote: The greatest thing you'll ever learn is just to love and be loved in return

  • @JamieH2000 glad your ERA went well and wasn’t too painful.  Praying for great results.  And March will be here before you know it.
    AFM, my RE wants me to naturally cycle but will also monitor my blood work every week to keep an eye on it for possible early ovulation.  In parallel to that, we are also planning to reserve a donor thru an agency.  So, let’s see what happens.

    @emmasemm Good luck with your second consult tmrw, and so sorry about the legal issue you have on your plate.  Hang in there!
  • @emmasemm when it rains it pours...I have some stressful things going on myself and I've been complaining about breathing feeling like i'm in my 9th month and I can now realize its all this extra stress that is making it harder to take a deep breathe...so with that being said hoping you're situation will resolve itself quickly!  Its so very hard to have other issues when you need to have a clear head!

    @JamieH2000 so glad to see ur update!  Hoping the results are what you want to see!  I know any extra time sux ass!  Just want everything to be perfect for you!

    @adc0417 glad your RE will keep watch on you!  Are you able to look at donor and still try a cycle of IVF...or did you decide to just move forward with donor?

    @hopefuljj thinking of you waiting to here some good news.  Praying you're waiting on AF to come and then what?  prep for FET?
    History of TTC in spoiler box
    TTC since 2014
    Unexplained Infertility - but I am 40...Low AMH .30
    7 - IUI (50mg-150mg Clomid) Feb - August 2016 all BFN 
    IVF#1 August 2016 (Antagonist protocol 4/5 eggs) Cancelled cycle :( RE thought I would get at least 10.
    IVF#2 Sept 2016 (microdose luporn pro - disappearing follies, ONLY ONE, convert to IUI) BFN
    IVF#3 November 2016 (4 ER, 3 F,  3DT)-BFP  with TWINS // MC both at almost 10wks  :'( 
    IVF#4 March 2017 //EPP  (10 ER (1 wonky so 9 ER) 7F, 3B (5AB, (2)5BB) PGS tested- ALL abnormal  :'( 
    IVF#5 April 2017 // EPP (7 ER, 7F yes! 6B) 2/5 day 4/6 day - 2 PGS normal! yes!! :)
    IVF#6 May 2017 // Antagonist didn't have time for Estrogen Priming...(4 ER, 3 F, 3B) (5AB, (2) 5BB) 2 PGS normal, yes!! :)
    IVF#7 June 2017 // EPP praying this is it and then on to an FET!

  • @Hopeful_mom No both DE and my IVF cycles will be at different clinics.  I know, I know we are kinda two timing, but just want to efficient and not waste time.  

    So, I wanted to ask those who have gone through DE, at what point would I need to be on BCP? Would it be after she has gone thru her screening? How quickly does it move from the time you pick a donor?  Also, can you just freeze those eggs/embryos for later?  Pls advice...
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