Infertility

Low AMH Level

18081838586167

Re: Low AMH Level

  • JamieH2000JamieH2000 member
    edited February 2018
    @hopeful_mom- Thanks chica :) Sorry things are stressful right now :( Just try to remember how hard you fought to get to this point and you are pregnant!! Nothing can be worse than the last few years right?

    @adc0417- responded to you on the DE thread, but also wanted to wish you luck on this natural cycle and hope your body ovulates and gets back into a normal cycle. My saddest months were when I had a cyst and my cycle was all messed up. Limbo is the worst!

    @emmasemm- Can't wait to hear about your consult!!!
    History in Spoiler

    Age: 32 (same with DH). Together since 2006, Married June 2013 and TTC since August 2015
    Diagnosis: Mild Endo, DOR (AMH of 1.5), Poor Quality Eggs/embryos, Displaced Window of Implantation (ERA Post Receptive)
    March-May 2016: 1 TI and 2 IUIs- BFN 
    June 2016- Laproscopy- found/removed mild endo and confirmed only 1 normal healthy ovary.
    August 2016- IVF #1 with Antagonist Protocol- Cancelled (2 lead follies), converted to IUI- BFN
    Oct-Nov 2016- IVF #2 with Estrogen Priming Micro Lupron Protocol, 2 eggs retrieved, day 3 transfer of 1- BFN
    January 2017- New RE, IVF#3 with Estrogen Priming Antagonist Protocol, 12 eggs, 8 mature, 6 fertilized, 2 day 5 early blasts transferred (none to freeze :(), BFN
    May 2017- Sept 2017- Starting Donor Egg process! Waiting for donor to be available... and then she is pregnant at baseline :(
    Oct 2017- Donor #2: 25R, 22M,18F, 12 blasts frozen! Fresh transfer cancelled due to thin lining with fluid :(
    Nov 2017- Hysterscopy to remove polyp
    Dec 2017- DE FET #1 on 12/8 on 2 perfect blasts- BFN and devastated
    Jan-Mar 2018- ERA #1- Post receptive by 24 hours, ERA #2 RECEPTIVE with 4 days of Progesterone
    Apr 2018- DE FET cancelled for lining issues :(
    Jun 2018- DE FET #2 of two 1AA blasts- first BFP ever! Beta 10dp5dt- 378, Beta 14dp5dt- 2840, Beta 16dp5dt- 4035, beta 18dp5dt- 10916. Due on 2/20 with one baby after a vanishing twin
    Baby Born born early @ 33.5 weeks due to Pre-e
    Back for # 2!
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  • @adc0417 thats amazing and i'm thrilled for you!  I remember someone said you have to commit one way or the other and i think that crap - so happy for you, theres a win so let it continue!!
    History of TTC in spoiler box
    TTC since 2014
    Unexplained Infertility - but I am 40...Low AMH .30
    7 - IUI (50mg-150mg Clomid) Feb - August 2016 all BFN 
    IVF#1 August 2016 (Antagonist protocol 4/5 eggs) Cancelled cycle :( RE thought I would get at least 10.
    IVF#2 Sept 2016 (microdose luporn pro - disappearing follies, ONLY ONE, convert to IUI) BFN
    IVF#3 November 2016 (4 ER, 3 F,  3DT)-BFP  with TWINS // MC both at almost 10wks  :'( 
    IVF#4 March 2017 //EPP  (10 ER (1 wonky so 9 ER) 7F, 3B (5AB, (2)5BB) PGS tested- ALL abnormal  :'( 
    IVF#5 April 2017 // EPP (7 ER, 7F yes! 6B) 2/5 day 4/6 day - 2 PGS normal! yes!! :)
    IVF#6 May 2017 // Antagonist didn't have time for Estrogen Priming...(4 ER, 3 F, 3B) (5AB, (2) 5BB) 2 PGS normal, yes!! :)
    IVF#7 June 2017 // EPP praying this is it and then on to an FET!

  • @Hopeful_mom Aww thanks so much for your support.  I’m so glad to have you all around 
  • moose1100moose1100 member
    edited February 2018
    Bump. I'm only 30! My estrogen and progesterone 8dpo were low (though still in the range to confirm o) and my AMH was 1. How can this be?? How scared should I be, and what can I do?
    my Vitamin d level is low at 26 (30 is low end of normal) and I know this can falsely lower AMH but... that much??
  • @hopeful_mom sorry you’re having stress. I really wish you would get a chance to relax and just sa our being PG for at least a part of your time.

    @adc0417 I’m pleased you can check out both options in parallel. I’m sure it gives you something to work on this cycle rather than just waiting, which for me always helps. 

    @hopefuljj how are you doing? Any idea on when PGS results will be through?

    @jamieh2000 how long do the ERA results take?

    @moose1100 welcome. Please make an intro thread as I didn’t see one from you so far. This means we all can understand your situation a bit better. Eg how long you’ve been trying, any other PGs etc. Please make sure to ***TW*** anything related to PG, kids or losses.
    Not sure what you mean by “Bump”?
    Firstly I hope you have an appointment with an RE to discuss all your results. They are best placed to answer your questions considering your full history and they are trained - we are not doctors, so please be careful following the advice of internet strangers. 
    I would suggest you talk to your doctor about them prescribing some vitamin d supplements and get the AMH retested in a few months. Also they should have done day 3 FSH levels. And done a trans vaginal ultrasound on day 3 to give you an antral follicle count (AFC). These three pieces of the puzzle are very important to view together. But even then they only give you an idea, not a perfect picture.
    An AMH of 1 which is stable is not alone a major issue.
    Please also ensure your DH has an SA. Checking ladies alone is crazy when approx 50% of cases involves male factor (or it is joint male/female).
    Finally please read through the history on this thread, get to know us and then give support in order to also receive it. We are a community who support each other through brilliant and truly awful times. We are not everyone’s personal google.

    AFM we had the phone consult last night. It took two hours. Yep. DH did almost fall asleep at one point lol. The RE had what I feel was a balanced approach - suggested some of the things I was hoping for, also clearly explained why som others would not be right for me. I felt he was willing to push, but not just trying to print money from us. He had a few ideas I hadn’t heard before.
    More details below:

    Like doing a double ER in one cycle - I always have 1-2 follies about 7-10mm bigger than the next group of 1-3 follies, so he said no problem they trigger and ER the first batch, then do it again for the second batch. Anyone heard of this before???

    Also we talked a lot about immune protocols. He said he will think about if it makes sense for me to do a modified transfer protocol already before the first stim cycle to reduce the inflammation, as that can also affect eggs. I’d also not heard this idea before!
    He definitely said he would want to work with my Rheumatologist to get an optimal cycle to do a transfer, and no way would he do fresh transfers as after all the meds, and the ER procedure of course my body is going to be in hyperactive immune mode. 

    Also as I had a positive result for Lupus Antikoagulant he said I need to see a haematologist and have further testing. Depending on some other test results it could mean a difference in the treatment we need for that - and that my risk of major implementation issues would either be 20% or 80%, So we need to know what we’re dealing with and treat it. 

    We are sleeping on it and discussing over the weekend.

    Biggest issue right now is finding somewhere that can do daily TVUS and same day result blood work for local monitoring. The clinic we were at before is not interested. And the OBs here don’t have short notice 8am appointments just waiting to see if I need them or not... plus the OBs skills with TVUS are definitely “limited” in comparison to an RE (doctors do all TVUS themselves here, no nurses doing them...).

    I have a feeling if we can conquer all this then running a small country would be a piece of cake in comparison  :D


    Me 43 DH 45
    Married 12/2016
    TTC #1 since 04/2015
    AMA, DOR (AMH 0.65, AFC 2-4) and autoimmune issues (RA, APS), low TSH, adenomyosis
    7 retrievals, 3 transfers
    Jun19 FET BFP, due date 7th March 2020, DD born Feb20
    Sep17 IVF1 - 1ER, 1F, 1ET, BFN
    Nov17 IVF2 - 1ER, 0F
    Jan18 IVF3 - 3ER, 1F, 1ET, BFN
    Feb18 - second opinion and additional testing
    Apr18 IVF4 - cancelled (E2 too high)
    May/Jun18 IVF4 - 4ER, 0M, 1F, 1 frozen day 3 (not best quality)
    Jun/Jul18 IVF5 - 5 ER, 3M, 2F, 2 frozen day 3 (not best quality)
    Jul/Aug18 IVF6 - 4ER, 3M, 2F, 2 frozen day 3 (good quality)
    Aug/Sep18 IVF7 - cancelled (cyst)
    Sep/Oct18 IVF7 - 3ER, 3M, 2F, 2 frozen Day 3 (excellent quality)
    Oct18 IVF8 - Cancelled (cyst and too low TSH)
    Oct18-Jan19 bringing TSH under control
    Feb19 ERA and hysteroscopy
    Mar19 Investigation for fibroid and adenomyosis
    Apr19 adenomyosis confirmed, polyps removed
    Jun19 FET after 2 months Lupron, autoimmune protocol, transferred two day 3 frozen embryos
    Sep17 - Pergoveris 10-17 Sep, Orgalutran 15-18 Sep, Ovitrelle 18 Sep, ER 20 Sep for 2 follies, 1 mature egg, fertilized, ET 1x 2d 4-cell embryo 22/09, 05/10 BFN
    Nov17 IVF2 - Pergoveris 2-14 Nov, Orgalutran 5-14 Nov, Ovitrelle 15 Nov, ER 17 Nov for 3 follies, 1 mature egg, did not fertilize
    Jan18 IVF3 - Pergoveris 30 Dec - 8 Jan, Orgalutran 5-8 Jan, Ovitrelle 9 Jan, ER 11 Jan 3 eggs, 2 mature, 1 fertilized, ET 1x 4d 12-cell embryo 15/01, 24/01 BFN
    May/Jun18 IVF4 - Rekovelle 25-29 May, Menogon 30May - 2Jun, Zomacton 25 27 29 31 May and 2Jun, Cetrotide 30May - 3Jun, Gonasi 3Jun, ER 5Jun 4 eggs, none mature, two matured overnight, 1 fertilized with ICSI, Frozen day 3 but not good quality
    Jun/Jul18 IVF5 - Rekovelle 21-24 June, Menogon 25Jun-3Jul, Puregon 4-5Jul, Zomacton 21 23 25 27 29 Jun, Cetrotide 25Jun-5Jul, Gonasi 6Jul, ER 8Jul 5 eggs, 3 mature, 2 fertilized with ICSI, 2 frozen day 3 but not good quality
    Jul/Aug18 IVF6 - Rekovelle 26-29 Jul, Menogon 30Jul-7Aug, Buserelin 26Jul-7Aug, Zomacton 26 28 30 Jul 1 3 Aug, Gonasi 7Aug, ER 9Aug 4 eggs, 3 mature, 2 fertilized (normal IVF), 2 frozen day 3 good quality
    Sep/Oct18 IVF7 - Menogon 19-30Sep, Buserelin 19-30Sep, Zomacton 19 21 23 25 27 Sep, Ovitrelle 1 Oct, ER 3 eggs, 3 mature, 2 fertilized with ICSI, 2 frozen day 3 excellent quality 

    Fav Quote: The greatest thing you'll ever learn is just to love and be loved in return

  • @moose1100- I agree with all of @emmasemm said. A recent study showed that low AMH (0.7 in this study) alone doesn't correlate with lower chance of getting pregnant. It came out last fall if you want to google it. I would focus on TTC for the next 6 months with OPKs. Your age should be on your side. Lots of ladies have lower AMH and just never know because they get pregnant easily.

    @emmasemm- wow a 2 hour consult! Glad they are willing to spend so much time and really listen to you! I thought about cycling or doing DE overseas, but the biggest concern for me was local monitoring too. I have honestly not heard of a double ER before. I don't quite understand how that would work, based on what I think I know about hormones and the ovulation process. My understanding is once you trigger, the other follicles wouldn't keep growing because the mature ones start producing progesterone. Has he successfully done 2 ERs with other patients? The immunology questions are interesting too. I think its good to get all the info you can on that. I wonder if there are any Germany or EU specific forums/groups that would have experience or advice about local monitoring. Is it possible to work remotely from your job for 2 weeks? Good idea to sleep on it for a weekend and digest!!
    History in Spoiler

    Age: 32 (same with DH). Together since 2006, Married June 2013 and TTC since August 2015
    Diagnosis: Mild Endo, DOR (AMH of 1.5), Poor Quality Eggs/embryos, Displaced Window of Implantation (ERA Post Receptive)
    March-May 2016: 1 TI and 2 IUIs- BFN 
    June 2016- Laproscopy- found/removed mild endo and confirmed only 1 normal healthy ovary.
    August 2016- IVF #1 with Antagonist Protocol- Cancelled (2 lead follies), converted to IUI- BFN
    Oct-Nov 2016- IVF #2 with Estrogen Priming Micro Lupron Protocol, 2 eggs retrieved, day 3 transfer of 1- BFN
    January 2017- New RE, IVF#3 with Estrogen Priming Antagonist Protocol, 12 eggs, 8 mature, 6 fertilized, 2 day 5 early blasts transferred (none to freeze :(), BFN
    May 2017- Sept 2017- Starting Donor Egg process! Waiting for donor to be available... and then she is pregnant at baseline :(
    Oct 2017- Donor #2: 25R, 22M,18F, 12 blasts frozen! Fresh transfer cancelled due to thin lining with fluid :(
    Nov 2017- Hysterscopy to remove polyp
    Dec 2017- DE FET #1 on 12/8 on 2 perfect blasts- BFN and devastated
    Jan-Mar 2018- ERA #1- Post receptive by 24 hours, ERA #2 RECEPTIVE with 4 days of Progesterone
    Apr 2018- DE FET cancelled for lining issues :(
    Jun 2018- DE FET #2 of two 1AA blasts- first BFP ever! Beta 10dp5dt- 378, Beta 14dp5dt- 2840, Beta 16dp5dt- 4035, beta 18dp5dt- 10916. Due on 2/20 with one baby after a vanishing twin
    Baby Born born early @ 33.5 weeks due to Pre-e
    Back for # 2!
  • @jamieH2000 I’m glad the ERA is done! And they better not have to redo it:-/  I know that 3/19 must feel so far away:(  your patience has been amazing.   

    @hopeful_mom I hope your stress level goes down!  And I hope you are able to enjoy your pregnancy some:).   AF  is on the way out.  I have no idea where to begin in regard to FET prep but I’m still waiting on PGS results so don’t know if I will have anything to transfer yet so should know in a few days!  I am terrified cuz if I do get a normie it took me so long to get to transfer so I feel like I should do allllll the things before transferring but I know my RE’s just gonna be like, let’s go for it.    Meanwhile I’m like, what about prednisone? Should I do baby Asprin and or lovenox cuz of the MTHFR!! Should I test for killer cells cuz of my Hashi?? Do a scratch? An ERA??   I guess I need to just wait for results before I worry about it.  Getting ahead of myself.  


    @emmasemm I hope your appointment went well!!  I hope the legal issue gets sorted out quickly. 

    @adc0417 I don’t have any DE advice but wanted to wish you luck none the less.  I like that you are maximizing by using 2 clinics!  Smart! 


    Me: Hashimoto Autoimune Disease
    Homozygous MTHFR Cr677
    DOR - AMH  .27 High FSH (don't even know how high)
    2 iui's to start - BFN 
    IVF 1 -3 made it do day 5!    2 5AA 1 6BB  PGS results =  all abnormal :(
    IVF 2 - stimmed for 19 days. insanity. Had 5 follicles that looked mature but only 2 contained mature eggs the others were empty.  Nothing made it to day 5
    IVF 3 - added in HGH - 4 mature follicles (had some empties again) 3 made it to day 5/6 for PGS (held for testing with next retrieval
    IVF 4 - Upped my dosage for the first time - Canceled 11 days into sims - looked like 1 follicle and we were afraid it was empty
    IVF 5 - Canceled -  looked like 1 follicle and we were afraid it was empty
    IVF 6 - 3 mature, 2 fertalized 1 made it to day 5 and sent for PGS

    Sent in IVF round 3 and 6 (4 embryos) for PGS testing and got 2 normal embryos!!!  1Boy and 1Girl. Took a little over a year to get those two embryos so demanded all sorts of test prior to attempting transfer. Did EFT, ERA and NK Cells testing.

    FET#1 - Intralipid drips, Prednisone, and did a depot lupron shot before starting the FET protocol
    Chemical pregnancy
    FET#2 - PGS normal boy - BFN
    Natural pregnancy - cycle following the FET2????   Miscarriage at 8 weeks.  viability scan had shown an enlarged yolk sac so I had been warned that it was likely not chromosonally normal :(

    DEIVF cycle - picked a donor who is willing to be open! Her cycle resulted in in 4 PGS Normal embryos
    1st transfer - chemical pregnancy
    2nd transfer - success, May 17 2020 due date!
  • Hi everyone,

    I took a few months off the boards to relax and not think about infertility. But, now I am back and sad to see some of you still here. I hoped you all got your happy endings...

    AFM, I started the 4th IVF yesterday. I only had 8 follicles but FSH was 8.8 and estrogen 30, so they started me. Two weeks ago I did AMH test on my own, and it came up 0.56. The last time I did AMH was 3 years ago before we started the TTC and it was 3.5. What a drastic change! Also, in the last few months I've been taking Ubiquinol so I hope it helped somehow. I finally ready the book "it starts with the egg" and I'm leaning towards taking DHEA, but a little unsure about the possible side effects plus my doctor didnt suggest one way or another. It is kind of late to take it since I already started the treatment, but it would help for future cycles if this fails too.. 
  • Hi @llky. I bought the DHEA and never took it but I still regret it after many cycles.  My RE tested my DHEA and said it was fine so I shouldn’t take it:-/. But I’ve seen so many ladies have a good outcome with it.

    AFM results are finally in.  2 normies.  One from the 9/17 cycle and one from this 1/17 cycle.   I’m so relieved because I was certain there would be 0 normies and I would have nothing to show after all this time and these cycles.  Now I’m going to fall down the rabbit hole (who am I kidding I spent the last 3 nights falling down it) about high thyroid antibodies and FET’s:(.   I just keep googling homozygous MTHFR, or Hashimoto with really high antibodies.  Taking in all the info but I mean I’m also not ready to beg my RE  for Lovenox and Prednisone and low dose naltrexone....the more I read the more I panic.  Going to try to take today to just enjoy having finally made it to FET!!!!!!!! 
    Me: Hashimoto Autoimune Disease
    Homozygous MTHFR Cr677
    DOR - AMH  .27 High FSH (don't even know how high)
    2 iui's to start - BFN 
    IVF 1 -3 made it do day 5!    2 5AA 1 6BB  PGS results =  all abnormal :(
    IVF 2 - stimmed for 19 days. insanity. Had 5 follicles that looked mature but only 2 contained mature eggs the others were empty.  Nothing made it to day 5
    IVF 3 - added in HGH - 4 mature follicles (had some empties again) 3 made it to day 5/6 for PGS (held for testing with next retrieval
    IVF 4 - Upped my dosage for the first time - Canceled 11 days into sims - looked like 1 follicle and we were afraid it was empty
    IVF 5 - Canceled -  looked like 1 follicle and we were afraid it was empty
    IVF 6 - 3 mature, 2 fertalized 1 made it to day 5 and sent for PGS

    Sent in IVF round 3 and 6 (4 embryos) for PGS testing and got 2 normal embryos!!!  1Boy and 1Girl. Took a little over a year to get those two embryos so demanded all sorts of test prior to attempting transfer. Did EFT, ERA and NK Cells testing.

    FET#1 - Intralipid drips, Prednisone, and did a depot lupron shot before starting the FET protocol
    Chemical pregnancy
    FET#2 - PGS normal boy - BFN
    Natural pregnancy - cycle following the FET2????   Miscarriage at 8 weeks.  viability scan had shown an enlarged yolk sac so I had been warned that it was likely not chromosonally normal :(

    DEIVF cycle - picked a donor who is willing to be open! Her cycle resulted in in 4 PGS Normal embryos
    1st transfer - chemical pregnancy
    2nd transfer - success, May 17 2020 due date!
  • @hopefuljj I'm thrilled to hear you have 2 normies!
    ****Siggy TW****
    natural pregnancy: 2008 
    Me: 28 (Hypothyroid), DH: 35
    Together since: 2010
    Married: 2013
    TTC: 2013
    Infertility: severe MFI, low AMH (0.5)
    Met RE: January 2016
    ER: 3/14 (4 follies, 6 eggs retrieved, 2 fertilized)
    fresh 3dt of 2 embryos= BFP (1 implanted)
    EDD w/ baby boy= 12/6/16
  • @hopefuljj omg! That’s soooooo awesome! Definitely bask in the news for a few days!


    On the other side the clinic we had the consult with last week was absolutely adamant about having all immune issues under control before transfer - especially as he put it “you don’t have embryos to spare”. He also suggested an ERA (or equivalent) before the first transfer - he said yes it’s “normally” only recommended after 2 PGS normal failures, but if you don’t have more embies than that and can afford it, then he suggests doing it first.

    On one hand I’m skeptical of undergoing treatments that are necessary (and paying for them), on the other hand for us to make more normies is a much bigger effort and expense - and no guarantee we can...

    @ilky sorry you’re here. Firstly check what your vitamin d levels are like as that can artificially lower AMH. Also, don’t take it alone - make sure you look at it in combination with day 3 FSH and AFC. 8 follicles and FSH 8 looks a bit to me like the AMH reading is too low... (but I’m not a doctor, just someone who has put more hour sleep into studying this than anything else in her life the last years...) 
    Were your previous IVF cycles several years ago? Of course how you respond to this cycle will tell you a lot. Feel free to share your protocol. Some REs will make you stop DHEA during stimming if you’re planning on a fresh transfer - so check with your RE before starting. 
    And like we wrote for another poster above, low AMH alone does not mean you can’t get pregnant, it’s just you have less eggs left and a worse response to meds to increase the eggs each month (for IUI or IVF).

    @jamieh2000 how goes it? Are you on your trip now?
    Me 43 DH 45
    Married 12/2016
    TTC #1 since 04/2015
    AMA, DOR (AMH 0.65, AFC 2-4) and autoimmune issues (RA, APS), low TSH, adenomyosis
    7 retrievals, 3 transfers
    Jun19 FET BFP, due date 7th March 2020, DD born Feb20
    Sep17 IVF1 - 1ER, 1F, 1ET, BFN
    Nov17 IVF2 - 1ER, 0F
    Jan18 IVF3 - 3ER, 1F, 1ET, BFN
    Feb18 - second opinion and additional testing
    Apr18 IVF4 - cancelled (E2 too high)
    May/Jun18 IVF4 - 4ER, 0M, 1F, 1 frozen day 3 (not best quality)
    Jun/Jul18 IVF5 - 5 ER, 3M, 2F, 2 frozen day 3 (not best quality)
    Jul/Aug18 IVF6 - 4ER, 3M, 2F, 2 frozen day 3 (good quality)
    Aug/Sep18 IVF7 - cancelled (cyst)
    Sep/Oct18 IVF7 - 3ER, 3M, 2F, 2 frozen Day 3 (excellent quality)
    Oct18 IVF8 - Cancelled (cyst and too low TSH)
    Oct18-Jan19 bringing TSH under control
    Feb19 ERA and hysteroscopy
    Mar19 Investigation for fibroid and adenomyosis
    Apr19 adenomyosis confirmed, polyps removed
    Jun19 FET after 2 months Lupron, autoimmune protocol, transferred two day 3 frozen embryos
    Sep17 - Pergoveris 10-17 Sep, Orgalutran 15-18 Sep, Ovitrelle 18 Sep, ER 20 Sep for 2 follies, 1 mature egg, fertilized, ET 1x 2d 4-cell embryo 22/09, 05/10 BFN
    Nov17 IVF2 - Pergoveris 2-14 Nov, Orgalutran 5-14 Nov, Ovitrelle 15 Nov, ER 17 Nov for 3 follies, 1 mature egg, did not fertilize
    Jan18 IVF3 - Pergoveris 30 Dec - 8 Jan, Orgalutran 5-8 Jan, Ovitrelle 9 Jan, ER 11 Jan 3 eggs, 2 mature, 1 fertilized, ET 1x 4d 12-cell embryo 15/01, 24/01 BFN
    May/Jun18 IVF4 - Rekovelle 25-29 May, Menogon 30May - 2Jun, Zomacton 25 27 29 31 May and 2Jun, Cetrotide 30May - 3Jun, Gonasi 3Jun, ER 5Jun 4 eggs, none mature, two matured overnight, 1 fertilized with ICSI, Frozen day 3 but not good quality
    Jun/Jul18 IVF5 - Rekovelle 21-24 June, Menogon 25Jun-3Jul, Puregon 4-5Jul, Zomacton 21 23 25 27 29 Jun, Cetrotide 25Jun-5Jul, Gonasi 6Jul, ER 8Jul 5 eggs, 3 mature, 2 fertilized with ICSI, 2 frozen day 3 but not good quality
    Jul/Aug18 IVF6 - Rekovelle 26-29 Jul, Menogon 30Jul-7Aug, Buserelin 26Jul-7Aug, Zomacton 26 28 30 Jul 1 3 Aug, Gonasi 7Aug, ER 9Aug 4 eggs, 3 mature, 2 fertilized (normal IVF), 2 frozen day 3 good quality
    Sep/Oct18 IVF7 - Menogon 19-30Sep, Buserelin 19-30Sep, Zomacton 19 21 23 25 27 Sep, Ovitrelle 1 Oct, ER 3 eggs, 3 mature, 2 fertilized with ICSI, 2 frozen day 3 excellent quality 

    Fav Quote: The greatest thing you'll ever learn is just to love and be loved in return

  • @hopefuljj- congrats girl!! 2 normies is an awesome result! Obviously we can never have too many embryos, but I really hope there is at least one, if not two, babies in there for you! I agree, moving onto FETs is scary! In the beat infertility podcasts, it seems like dr rodgers is pretty adamant that mtfhr doesn’t affect anything, except needing folate. As someone who “should be pregnant right now” after transferring two perfect embryos, I would reco doing an ERA first. It will cost you a month, but I think it’s worth the $1-2k to make sure you are transferring at the right time since you don’t have room for error here. As far as I have read, high thyroid antibodies only mess with your ovaries and shouldn’t affect implantation. However, my friend was recently diagnosed with super high TAB and was able to lower them thru diet (the whole 30). Something you could consider if you want to do everything possible. Honestly tho, I’m so glad excited for you and deserve this so much!!

    @ilky- good to hear from you! Unfortunately some of us are still here but hopefully for not too much longer! I would caution the use of DHEa. My second RE had me start it without tearing my natural levels. I really think it messed up my cycles. If you aren’t naturally low of it, it can just make things worse. When are you getting started again and what protocol are you doing?

    @emmasemm- doing good here, just waiting for ERA results! I am in Hawaii this week so that is helping me pass the time for sure :) did you and DH come to any decisions about your next steps?
    History in Spoiler

    Age: 32 (same with DH). Together since 2006, Married June 2013 and TTC since August 2015
    Diagnosis: Mild Endo, DOR (AMH of 1.5), Poor Quality Eggs/embryos, Displaced Window of Implantation (ERA Post Receptive)
    March-May 2016: 1 TI and 2 IUIs- BFN 
    June 2016- Laproscopy- found/removed mild endo and confirmed only 1 normal healthy ovary.
    August 2016- IVF #1 with Antagonist Protocol- Cancelled (2 lead follies), converted to IUI- BFN
    Oct-Nov 2016- IVF #2 with Estrogen Priming Micro Lupron Protocol, 2 eggs retrieved, day 3 transfer of 1- BFN
    January 2017- New RE, IVF#3 with Estrogen Priming Antagonist Protocol, 12 eggs, 8 mature, 6 fertilized, 2 day 5 early blasts transferred (none to freeze :(), BFN
    May 2017- Sept 2017- Starting Donor Egg process! Waiting for donor to be available... and then she is pregnant at baseline :(
    Oct 2017- Donor #2: 25R, 22M,18F, 12 blasts frozen! Fresh transfer cancelled due to thin lining with fluid :(
    Nov 2017- Hysterscopy to remove polyp
    Dec 2017- DE FET #1 on 12/8 on 2 perfect blasts- BFN and devastated
    Jan-Mar 2018- ERA #1- Post receptive by 24 hours, ERA #2 RECEPTIVE with 4 days of Progesterone
    Apr 2018- DE FET cancelled for lining issues :(
    Jun 2018- DE FET #2 of two 1AA blasts- first BFP ever! Beta 10dp5dt- 378, Beta 14dp5dt- 2840, Beta 16dp5dt- 4035, beta 18dp5dt- 10916. Due on 2/20 with one baby after a vanishing twin
    Baby Born born early @ 33.5 weeks due to Pre-e
    Back for # 2!
  • @hopefuljj I have MTHFR. I don’t remember if it is homozygous or heterozygous. I was told to take Metanx, special folate. I also took it upon myself to add baby aspirin, just something I’d read on another forum that a few women with MTHFR did.  I think my re put me on prednisone for the FET, but I don’t know if that’s just her normal protocol. Congratulations on 2 normies!  That’s fantastic!  
    Me:32 DH:36
    Me: DOR, poor egg quality, MTHFR
    DH: MFI
    TTC since 3/2014
    2015: 3 IUI's-BFN
    12/2015: 1st IVF cycle-(9 follicles retrieved, 5 mature, 3 fertilized w/ICSI, transferred 1 excellent and 1 good embryo on day 3)-chemical pregnancy
    3/2016: 2nd IVF cycle- canceled (3 follicles retrieved, 3 mature, all fertilized w/ICSI, 1 fragmented, 2 arrested) 
    3/2016: RE suggested donor eggs- taking an ivf break and to supplement 
    9/2016: 3rd ivf cycle-cancelled due to early ovulation
    Oct./Nov 2016: 4th ivf cycle- EPP-AFC:5, retrieved 10, 10 mature, 8 fertilized with ICSI, 6 blastocysts biopsied and frozen. 3 CCS normal embryos
    1/9/17: transferred 1 embryo-BFP 1/16
    1/18/17: beta #1-104
    1/20/17: beta #2-174
    2/2/17: first u/s, heartbeat of 107 at 6w1d
    7/20/17: baby boy born at 30+3 via emergency c-section 


  • Ladies thank you soooo much for your kind words!! I’ve completely lost my mind and am back to my obsessive research ways.  @capps42613 thank you so much!!!! I am very excited:)! And terrified! Ha:). 

    @emmasemm  I am absolutely feeling so torn between wanting to do All the tests and take all the drugs and also not wanting to dig up more money and spend more time on this stuff:(. It is so hard but these 2 embabies are soooo precious and it could take me another year to get a normie or maybe I would never get another one.  Where is my crystal ball?  The question I always come back to:)

    @jamieH2000 I def want to ask about ERA.  I know some RE’s don’t believe in it or think it switches from month to month but I feel like I totally agree with you!! I also kinda want a scratch:-/ the issue with Hashi is that they say 50% of women with thyroid antibodies also have problems with NK cells in the uterus so they recommend intralipid therapy plus prednisone or IVIG.   I have done all sorts of strict diets, I don’t know if you remember but I am 100 % gluten free because of the Hashi and gave up sugar and all dairy for maaaany months.  My antibodies never came down so I reintroduced dairy a month ago and decided to live a little:) maybe I should just do whole 30???     @kp214 I take a methyl folate in my prenatal that I selected because of the MTHFR:) I’m going to look up the metanx cuz I keep seeing that come up to make sure I’m basically taking the same thing. If you are Only hetero for it they tend to say baby aspirin might be enough but the more I read the more it seems like if you are homozygous you need that plus lovenox???  Or if your homocysteine levels are elevated with any MTHFR mutation you might need lovenox too.  Brain is on overdrive and I need to go to bed!!!  Thank you again ladies!!!!



    Me: Hashimoto Autoimune Disease
    Homozygous MTHFR Cr677
    DOR - AMH  .27 High FSH (don't even know how high)
    2 iui's to start - BFN 
    IVF 1 -3 made it do day 5!    2 5AA 1 6BB  PGS results =  all abnormal :(
    IVF 2 - stimmed for 19 days. insanity. Had 5 follicles that looked mature but only 2 contained mature eggs the others were empty.  Nothing made it to day 5
    IVF 3 - added in HGH - 4 mature follicles (had some empties again) 3 made it to day 5/6 for PGS (held for testing with next retrieval
    IVF 4 - Upped my dosage for the first time - Canceled 11 days into sims - looked like 1 follicle and we were afraid it was empty
    IVF 5 - Canceled -  looked like 1 follicle and we were afraid it was empty
    IVF 6 - 3 mature, 2 fertalized 1 made it to day 5 and sent for PGS

    Sent in IVF round 3 and 6 (4 embryos) for PGS testing and got 2 normal embryos!!!  1Boy and 1Girl. Took a little over a year to get those two embryos so demanded all sorts of test prior to attempting transfer. Did EFT, ERA and NK Cells testing.

    FET#1 - Intralipid drips, Prednisone, and did a depot lupron shot before starting the FET protocol
    Chemical pregnancy
    FET#2 - PGS normal boy - BFN
    Natural pregnancy - cycle following the FET2????   Miscarriage at 8 weeks.  viability scan had shown an enlarged yolk sac so I had been warned that it was likely not chromosonally normal :(

    DEIVF cycle - picked a donor who is willing to be open! Her cycle resulted in in 4 PGS Normal embryos
    1st transfer - chemical pregnancy
    2nd transfer - success, May 17 2020 due date!
  • Thank you ladies! @emmasemm my failed cycles were just last September-November. My RE never measures AMH. Just the Antral count and FSH. But, I got an order from my gyno because I wanted to see what it was. I tested it last month on day 3 but I wasn’t doing the treatment so I don’t know the count and fsh at that time. I know Amh doesn’t really prevent people getting pregnant but as you can see from my siggy that I’ve been trying about 3 years, done 4 iuis, tried 3 IVF s. So not sure what else can cause all this?.... I’m on the same protocol as the last one. Started with 425iu follistim, he will add menopur at some point and then garinelex. 
    @JamieH2000 hi there! my RE didn’t suggest any supplement. I read the “it starts with the egg” and asked the head nurse who said it’s ok to take if I wanted. So no tests are done. I am kind of hesitant to take it, but I heard good stories including one of my coworker. I ordered it. Uggh so hard to decide what’s best for me. I mean my doctor didn’t even suggest coq10, I have to do the all the research. Btw, enjoy Hawaii and hope you can relax a bit.
    @hopefuljj i had hashimotos but through diet and healthy lifestyle it’s gone completely (or almost) I never used medication. No gluten, no dairy, no sugar no grains diet helped me a lot and now I’m adding some grains (sprouted), little goat dairy and little agave. As for mtfhr, I have a mild/moderate case of it. All I’m told to take is metafolate about 3 grams a day. But you have to take it along with b12 for it to be used by your body. Good luck!
  • Hopeful_momHopeful_mom member
    edited February 2018
    @hopefuljj Yes!!!! YES!!!!

    Baby just kicked for you since her mama is sooooo excited!!! You earned this!! That's 1/2 lady! So freaking happy!! See how every cycle can have that golden egg!! So you know the gender?
    i hope u parties and enjoyed the good news!!! Now to get this body ready!!!  It's so hard as we kno!! I'm on metanex and baby aspirin. I have mthfr and dr was against lovenox every time I brought it up.  Nk cell is always the thing I was concerned about too, didn't know haishimos could play a role in that.  So happy to see ur update!! It's  always so hard to know what to do next when it stops all we've dreamed about to get to especially!! 
    Is ivig a drug? All the other drugs u mentioned seem to be taken by people that do have immunology issues! Have u spoken with dr brakeman here in NY? Did I ask u that already?

    @JamieH2000 enjoy Hawaii one step closer!!

    @llky hope ur time away did you some good!! My dr didn't think it was necessary to take extra supplements but then after a year and so many ppl here were on them I decided I should be helping the cause as much as possible which at least help keep my Amh at bay.  Dhea, vitamin D and coq10 was what I added. Amh was at .30 and a year later .40.

    @emmasemm I love reading all ur posts and knowledge u share with all!  So have u decided the next step? Many options. 
    History of TTC in spoiler box
    TTC since 2014
    Unexplained Infertility - but I am 40...Low AMH .30
    7 - IUI (50mg-150mg Clomid) Feb - August 2016 all BFN 
    IVF#1 August 2016 (Antagonist protocol 4/5 eggs) Cancelled cycle :( RE thought I would get at least 10.
    IVF#2 Sept 2016 (microdose luporn pro - disappearing follies, ONLY ONE, convert to IUI) BFN
    IVF#3 November 2016 (4 ER, 3 F,  3DT)-BFP  with TWINS // MC both at almost 10wks  :'( 
    IVF#4 March 2017 //EPP  (10 ER (1 wonky so 9 ER) 7F, 3B (5AB, (2)5BB) PGS tested- ALL abnormal  :'( 
    IVF#5 April 2017 // EPP (7 ER, 7F yes! 6B) 2/5 day 4/6 day - 2 PGS normal! yes!! :)
    IVF#6 May 2017 // Antagonist didn't have time for Estrogen Priming...(4 ER, 3 F, 3B) (5AB, (2) 5BB) 2 PGS normal, yes!! :)
    IVF#7 June 2017 // EPP praying this is it and then on to an FET!

  • @hopefuljj- the good thing about the ERA is that it is also a scratch! I can attest to the lovely feeling of them “roughing” up the uterus with the biopsy! I did forget you were on such a strict diet already. I think the whole 30 is pretty much similar to what you are doing... maybe a little less carbs and more veggies/protein. The whole reproductive immunology stuff is still confusing to me... I know some who have seen kwak Kim in Chicago and have had great success. But I also trust dr rodgers a ton and she doesn’t really buy into RI as far as I can tell...it’s so hard to know what to do!

    @ilky- sorry if you have a siggy, but I’m on mobile right now. How did your first 3 IVfs go? I hear you on wondering what is wrong... I also did 3 IUIs and 3 ivfs before moving on to DE. Despite all my cycles being when I was 28/29, I have never had a positive and I just didn’t get good embryos in day 5, even once we found the right protocol. I guess I just have an egg quality problem... I will always wonder how though. Never smoked a cig or done any sort of drug in my life, BMI always between 22-25... I guess this is the cards I was dealt. Obviously I hope this isn’t your problem too... but unfortunately when someone is “unexplained”, especially with lower AMh at a young age, I think it’s usually egg quality :( DHEA may help you, but I would really ask your office To test your natural levels first. I really hope number 4 is the lucky cycle for you!!
    History in Spoiler

    Age: 32 (same with DH). Together since 2006, Married June 2013 and TTC since August 2015
    Diagnosis: Mild Endo, DOR (AMH of 1.5), Poor Quality Eggs/embryos, Displaced Window of Implantation (ERA Post Receptive)
    March-May 2016: 1 TI and 2 IUIs- BFN 
    June 2016- Laproscopy- found/removed mild endo and confirmed only 1 normal healthy ovary.
    August 2016- IVF #1 with Antagonist Protocol- Cancelled (2 lead follies), converted to IUI- BFN
    Oct-Nov 2016- IVF #2 with Estrogen Priming Micro Lupron Protocol, 2 eggs retrieved, day 3 transfer of 1- BFN
    January 2017- New RE, IVF#3 with Estrogen Priming Antagonist Protocol, 12 eggs, 8 mature, 6 fertilized, 2 day 5 early blasts transferred (none to freeze :(), BFN
    May 2017- Sept 2017- Starting Donor Egg process! Waiting for donor to be available... and then she is pregnant at baseline :(
    Oct 2017- Donor #2: 25R, 22M,18F, 12 blasts frozen! Fresh transfer cancelled due to thin lining with fluid :(
    Nov 2017- Hysterscopy to remove polyp
    Dec 2017- DE FET #1 on 12/8 on 2 perfect blasts- BFN and devastated
    Jan-Mar 2018- ERA #1- Post receptive by 24 hours, ERA #2 RECEPTIVE with 4 days of Progesterone
    Apr 2018- DE FET cancelled for lining issues :(
    Jun 2018- DE FET #2 of two 1AA blasts- first BFP ever! Beta 10dp5dt- 378, Beta 14dp5dt- 2840, Beta 16dp5dt- 4035, beta 18dp5dt- 10916. Due on 2/20 with one baby after a vanishing twin
    Baby Born born early @ 33.5 weeks due to Pre-e
    Back for # 2!
  • @JamieH2000 what is ERA? I'm not familiar with that procedure... Mf first IVF was in Sept 2017, I had 7 follies and FSH 11 so my RE cancelled the cycle. 2nd IVF was better, I started with 11 follies and FSH was 9. I didnt respond to meds, and after 11 days of stims only 3 follies grew. We had to cancel the cycle due to low chances, and the fact that we could not afford two full IVFs. Last try, was same as the first one, FSH was 18. So, I'm hopeful this time, but cautious...
  • @hopefuljj so excited for your 2 embabies!!!

    @JamieH2000 hoping you’re enjoying and relaxing your mind and body in Hawaii 

    @llky hoping this is the cycle where you find success.  I feel that they should’ve done the ER your 2nd cycle even with 3 follies.  There are so many cases where they find your golden egg within those 3-4 follies.  I’m sorry if I missed it, but what was your AFC and FSH this time?
  • I agree with @adc0417. I had 4 follies & got my golden egg. On the other hand I do understand that $ is always the issue!
    ****Siggy TW****
    natural pregnancy: 2008 
    Me: 28 (Hypothyroid), DH: 35
    Together since: 2010
    Married: 2013
    TTC: 2013
    Infertility: severe MFI, low AMH (0.5)
    Met RE: January 2016
    ER: 3/14 (4 follies, 6 eggs retrieved, 2 fertilized)
    fresh 3dt of 2 embryos= BFP (1 implanted)
    EDD w/ baby boy= 12/6/16
  • @adc0417 @capps42613 we could’ve done the ER on the second IVF but we couldn’t afford to do two IVFs if that one resulted in no good eggs/embryos so we cancelled it. We did iui instead since I took stims for 11 days and had 3 good looking follicles but it didn’t work. This time I started with 8 follies that they can count, and fsh was 8.8. I’m praying all will respond to stims and grow to mature at the same time and each will have one or more beautiful healthy eggs :)
  • @llky I was going to give the same advice as the ladies above...my very first cycle my dr thought I wouldve responded better and we didn't go for it.  Changed my protocol on round 2 and I did even worse and switched to an IUI.  Then on round 3 I wanted to see if I could just make it to ER and see what I was working with...its very hard each cycle.
    The cycle that gave me the most eggs didn't give me any normal embryos when I look back...each cycle is different.  Once cycle I had 3 and got 2 normies that round.  AND I had 6 another time and got 2 back that round too.  Its a gamble every time for sure.  you do have age on your side so I totally get wanting more and hopefully you do have your golden batch in this cycle!
    History of TTC in spoiler box
    TTC since 2014
    Unexplained Infertility - but I am 40...Low AMH .30
    7 - IUI (50mg-150mg Clomid) Feb - August 2016 all BFN 
    IVF#1 August 2016 (Antagonist protocol 4/5 eggs) Cancelled cycle :( RE thought I would get at least 10.
    IVF#2 Sept 2016 (microdose luporn pro - disappearing follies, ONLY ONE, convert to IUI) BFN
    IVF#3 November 2016 (4 ER, 3 F,  3DT)-BFP  with TWINS // MC both at almost 10wks  :'( 
    IVF#4 March 2017 //EPP  (10 ER (1 wonky so 9 ER) 7F, 3B (5AB, (2)5BB) PGS tested- ALL abnormal  :'( 
    IVF#5 April 2017 // EPP (7 ER, 7F yes! 6B) 2/5 day 4/6 day - 2 PGS normal! yes!! :)
    IVF#6 May 2017 // Antagonist didn't have time for Estrogen Priming...(4 ER, 3 F, 3B) (5AB, (2) 5BB) 2 PGS normal, yes!! :)
    IVF#7 June 2017 // EPP praying this is it and then on to an FET!

  • @Ilky yeah! I'll be praying for success!! you got it!
  • @ilky- ERA is endometrial receptivity array. It’s usually done for repeated failed transfers. It’s a mock transfer cycle with a biopsy instead of a transfer. It’s supposed to show if your uterus is receptive on the normal day 5 transfer timing. I really hope this ivf cycle is the one for you! Did you do Birth control or any estrogen priming before your cycles? Birth control isn’t usually recommended for DOR, but estrogen priming can be used to lower FSH below starting stims I believe. 
    History in Spoiler

    Age: 32 (same with DH). Together since 2006, Married June 2013 and TTC since August 2015
    Diagnosis: Mild Endo, DOR (AMH of 1.5), Poor Quality Eggs/embryos, Displaced Window of Implantation (ERA Post Receptive)
    March-May 2016: 1 TI and 2 IUIs- BFN 
    June 2016- Laproscopy- found/removed mild endo and confirmed only 1 normal healthy ovary.
    August 2016- IVF #1 with Antagonist Protocol- Cancelled (2 lead follies), converted to IUI- BFN
    Oct-Nov 2016- IVF #2 with Estrogen Priming Micro Lupron Protocol, 2 eggs retrieved, day 3 transfer of 1- BFN
    January 2017- New RE, IVF#3 with Estrogen Priming Antagonist Protocol, 12 eggs, 8 mature, 6 fertilized, 2 day 5 early blasts transferred (none to freeze :(), BFN
    May 2017- Sept 2017- Starting Donor Egg process! Waiting for donor to be available... and then she is pregnant at baseline :(
    Oct 2017- Donor #2: 25R, 22M,18F, 12 blasts frozen! Fresh transfer cancelled due to thin lining with fluid :(
    Nov 2017- Hysterscopy to remove polyp
    Dec 2017- DE FET #1 on 12/8 on 2 perfect blasts- BFN and devastated
    Jan-Mar 2018- ERA #1- Post receptive by 24 hours, ERA #2 RECEPTIVE with 4 days of Progesterone
    Apr 2018- DE FET cancelled for lining issues :(
    Jun 2018- DE FET #2 of two 1AA blasts- first BFP ever! Beta 10dp5dt- 378, Beta 14dp5dt- 2840, Beta 16dp5dt- 4035, beta 18dp5dt- 10916. Due on 2/20 with one baby after a vanishing twin
    Baby Born born early @ 33.5 weeks due to Pre-e
    Back for # 2!
  • @ilky I’m +1 for not waiting for 10 follies before doing an ER. Otherwise I would probably never do an ER.

    @jamieh2000 +1 for trusting Dr Rogers!

    @hopefuljj I’m also looking at a full immune protocol right now, including Intralipids and/or IVIG before my first retrieval cycle with the new RE. I think I posted about his ideas a week ago? If you want more details just PM me any time.

    @hopeful_mom I cannot believe how far along you are! It’s totally crazy! I don’t think i asked for a few weeks so... how’s the “fire vag”???  :D

    AFM still battling with getting everything set up with the new clinic - well the battle is more local monitoring, language barrier and additional tests they want which aren’t also possible locally... but probably means we won’t make it to start with my Feb cycle, but instead March. However as I’m yet to O on CD16 who knows!

    Also in case @offtoneverland needs/wants to come and join us here, please give her a warm welcome and the benefit of your experience. She is a friend from TTGP who just had a first low AMH result and I think you all know anything we can do to help her navigate this maze of low AMH helps just a little.
    Me 43 DH 45
    Married 12/2016
    TTC #1 since 04/2015
    AMA, DOR (AMH 0.65, AFC 2-4) and autoimmune issues (RA, APS), low TSH, adenomyosis
    7 retrievals, 3 transfers
    Jun19 FET BFP, due date 7th March 2020, DD born Feb20
    Sep17 IVF1 - 1ER, 1F, 1ET, BFN
    Nov17 IVF2 - 1ER, 0F
    Jan18 IVF3 - 3ER, 1F, 1ET, BFN
    Feb18 - second opinion and additional testing
    Apr18 IVF4 - cancelled (E2 too high)
    May/Jun18 IVF4 - 4ER, 0M, 1F, 1 frozen day 3 (not best quality)
    Jun/Jul18 IVF5 - 5 ER, 3M, 2F, 2 frozen day 3 (not best quality)
    Jul/Aug18 IVF6 - 4ER, 3M, 2F, 2 frozen day 3 (good quality)
    Aug/Sep18 IVF7 - cancelled (cyst)
    Sep/Oct18 IVF7 - 3ER, 3M, 2F, 2 frozen Day 3 (excellent quality)
    Oct18 IVF8 - Cancelled (cyst and too low TSH)
    Oct18-Jan19 bringing TSH under control
    Feb19 ERA and hysteroscopy
    Mar19 Investigation for fibroid and adenomyosis
    Apr19 adenomyosis confirmed, polyps removed
    Jun19 FET after 2 months Lupron, autoimmune protocol, transferred two day 3 frozen embryos
    Sep17 - Pergoveris 10-17 Sep, Orgalutran 15-18 Sep, Ovitrelle 18 Sep, ER 20 Sep for 2 follies, 1 mature egg, fertilized, ET 1x 2d 4-cell embryo 22/09, 05/10 BFN
    Nov17 IVF2 - Pergoveris 2-14 Nov, Orgalutran 5-14 Nov, Ovitrelle 15 Nov, ER 17 Nov for 3 follies, 1 mature egg, did not fertilize
    Jan18 IVF3 - Pergoveris 30 Dec - 8 Jan, Orgalutran 5-8 Jan, Ovitrelle 9 Jan, ER 11 Jan 3 eggs, 2 mature, 1 fertilized, ET 1x 4d 12-cell embryo 15/01, 24/01 BFN
    May/Jun18 IVF4 - Rekovelle 25-29 May, Menogon 30May - 2Jun, Zomacton 25 27 29 31 May and 2Jun, Cetrotide 30May - 3Jun, Gonasi 3Jun, ER 5Jun 4 eggs, none mature, two matured overnight, 1 fertilized with ICSI, Frozen day 3 but not good quality
    Jun/Jul18 IVF5 - Rekovelle 21-24 June, Menogon 25Jun-3Jul, Puregon 4-5Jul, Zomacton 21 23 25 27 29 Jun, Cetrotide 25Jun-5Jul, Gonasi 6Jul, ER 8Jul 5 eggs, 3 mature, 2 fertilized with ICSI, 2 frozen day 3 but not good quality
    Jul/Aug18 IVF6 - Rekovelle 26-29 Jul, Menogon 30Jul-7Aug, Buserelin 26Jul-7Aug, Zomacton 26 28 30 Jul 1 3 Aug, Gonasi 7Aug, ER 9Aug 4 eggs, 3 mature, 2 fertilized (normal IVF), 2 frozen day 3 good quality
    Sep/Oct18 IVF7 - Menogon 19-30Sep, Buserelin 19-30Sep, Zomacton 19 21 23 25 27 Sep, Ovitrelle 1 Oct, ER 3 eggs, 3 mature, 2 fertilized with ICSI, 2 frozen day 3 excellent quality 

    Fav Quote: The greatest thing you'll ever learn is just to love and be loved in return

  • @emmasemm Thank you for directing me to this thread!

    Hi everyone, it's so great to know this thread exists because I have no idea what to think right now and I'm in a bit of a shock. **TW--my intro will mention loss** I started TTC#2 in June 2017, and since then have had 3 early losses in August, October, and December. I started testing with an RE a couple of weeks ago and just found out today that my AMH is .12, and I'm only 30 years old. I had my other baseline testing on cd4--my AFC was around 6-8, my FSH was 9.2, and everything else (estrogen, TSH, etc) was normal. I have an appointment with my RE first thing on Monday to talk through the results and see what's next. The nurse mentioned they want to test me Fragile X as well. 
    I look forward to getting to know all of you and learning from your experience. 
    *TW*
    Me: 31 | DH: 33
    DD1: 8/2014  <3
    TTC #2: 6/2017
    BFP 8/3/2017 | CP 8/4
    BFP 10/16/2017 | CP 10/21
    BFP 12/18/2017 | CP 12/28
    BFP 2/15/2018 | EDD: November 2nd | It's a girl!
    DD2: 10/2018  <3
  • IlkyIlky member
    edited February 2018
    Thank you ladies! I had my appointment today (had 5 days of stims) and the doctor was optimistic. I have 7 growing follicles and a few smaller ones. So, definitely better than the last cycle when only 3 follicles out of 11 grew. I am trying to be cautiously optimistic, because I know it doesn't end there. But, at least it gave me some hopes :)

    @JamieH2000 I didn't use BCP or estrogen, when I asked about the estrogen my dr. didnt think it was good for me. Have you already done the ERA or you are going to? Sorry, I missed that part. If you have, did you get the results? 
  • @Ilky Totally excited for you and your DH I'm glad this cycle is going much more smooth than the last one!! 
  • @emmasemm- if anyone can figure out everything quickly to do a cycle abroad, it is you!! It’s amazing how hard all this stuff is sometimes! Even doing everything locally has been annoying. Since I am nearly starting year 3 with an RE, I am now trying to get physical results from my GYN to start my next cycle. They have always insisted on a breast exam, which isn’t always routinely done here, especially under 30! I really hope you can get started with your next cycle. Waiting is just the worst. 

    @ilky- this cycle sounds very promising! I hope it continues and I will be thinking of you! Going back again in two days?! I had the ERa last wed so just waiting for results. Hopefully early next week!

    @offtoneverland- sorry you are here with us but it’s a great group of ladies! Low AMh is a scary diagnosis, but recent research came out that just having low AMH doesn’t correlate with IF. Your AMH was likely low when you had your first and most ladies just don’t know. I am guessing there is something else going on too. HAve you had any of your losses tested? Unfortunately the best way to make sure you had good embryos would be ivf with PGS, but low AMH and low AFC doe make it harder to get a lot of embryos. I hope your RE has som good ideas. I would also ask them to test you for thyroid antibodies. They can attach your ovaries and cause the low AMh/ DOR.
    History in Spoiler

    Age: 32 (same with DH). Together since 2006, Married June 2013 and TTC since August 2015
    Diagnosis: Mild Endo, DOR (AMH of 1.5), Poor Quality Eggs/embryos, Displaced Window of Implantation (ERA Post Receptive)
    March-May 2016: 1 TI and 2 IUIs- BFN 
    June 2016- Laproscopy- found/removed mild endo and confirmed only 1 normal healthy ovary.
    August 2016- IVF #1 with Antagonist Protocol- Cancelled (2 lead follies), converted to IUI- BFN
    Oct-Nov 2016- IVF #2 with Estrogen Priming Micro Lupron Protocol, 2 eggs retrieved, day 3 transfer of 1- BFN
    January 2017- New RE, IVF#3 with Estrogen Priming Antagonist Protocol, 12 eggs, 8 mature, 6 fertilized, 2 day 5 early blasts transferred (none to freeze :(), BFN
    May 2017- Sept 2017- Starting Donor Egg process! Waiting for donor to be available... and then she is pregnant at baseline :(
    Oct 2017- Donor #2: 25R, 22M,18F, 12 blasts frozen! Fresh transfer cancelled due to thin lining with fluid :(
    Nov 2017- Hysterscopy to remove polyp
    Dec 2017- DE FET #1 on 12/8 on 2 perfect blasts- BFN and devastated
    Jan-Mar 2018- ERA #1- Post receptive by 24 hours, ERA #2 RECEPTIVE with 4 days of Progesterone
    Apr 2018- DE FET cancelled for lining issues :(
    Jun 2018- DE FET #2 of two 1AA blasts- first BFP ever! Beta 10dp5dt- 378, Beta 14dp5dt- 2840, Beta 16dp5dt- 4035, beta 18dp5dt- 10916. Due on 2/20 with one baby after a vanishing twin
    Baby Born born early @ 33.5 weeks due to Pre-e
    Back for # 2!
  • @JamieH2000 Thank you! I have not had any of my losses tested as they happened naturally and very early on. They were technically CPs. Thank you for the tip about the thyroid antibodies. I'll be sure to ask about that. 
    *TW*
    Me: 31 | DH: 33
    DD1: 8/2014  <3
    TTC #2: 6/2017
    BFP 8/3/2017 | CP 8/4
    BFP 10/16/2017 | CP 10/21
    BFP 12/18/2017 | CP 12/28
    BFP 2/15/2018 | EDD: November 2nd | It's a girl!
    DD2: 10/2018  <3
  • @offtoneverland welcome, sorry you have to find us here. But we're a great support group! I've already went through IVF with a low AMH of 0.5 @ 28 years old. I basically stick around to lend support and hope. Sorry to hear of your losses. Best of luck!
    ****Siggy TW****
    natural pregnancy: 2008 
    Me: 28 (Hypothyroid), DH: 35
    Together since: 2010
    Married: 2013
    TTC: 2013
    Infertility: severe MFI, low AMH (0.5)
    Met RE: January 2016
    ER: 3/14 (4 follies, 6 eggs retrieved, 2 fertilized)
    fresh 3dt of 2 embryos= BFP (1 implanted)
    EDD w/ baby boy= 12/6/16
  • Hopeful_momHopeful_mom member
    edited February 2018
    @hopefuljj I hope you're celebrating as I still am :)

    @emmasemm if anyone can make this work you can! I really feel like we all need to get together and right a self help book on ivf! Have u found a place u can do the local monitoring?

    @offtoneverland this is one of the best place she you can find support and know you're not alone!! So sorry for your previous losses!!! Good thing is you can conceive!  Many ladies have already given the same advice I would.  You are still on the younger side so hopefully u still have a bunch of golden eggs waiting!! For me the low Amh means for us that we do have that time clock going that can't be ignored!  Sorry if I missed it were u on progesterone through the previous pregnancies?

    Update on baby and I below....
    AFM: I'm 23 weeks  yay!!  Its been a week full of testing for me and baby!  OB had me go to a cardiologist since i was complaining of my breathing.  Wore a heart monitor for 24hrs and had an echo for myself...waiting to hear the results.  Assuming all is ok.  My Dr hears my hyperventilating in my breathing and believes its all from anxiety and stress.  He knows with everything I've been through why...but still says I need to try to relax...so lets hope I can work on that.
    Had baby's echo today and at first the baby wasn't in the right position BUT then baby did a flip and all went smoothly!  Since this was done in the hospital and english was not the womans first language she really didn't walk me through what she was doing BUT she knew I was nervous and said I should be able to sleep easy tonight SO I'm just going to stay positive and hope all is ok!

    History of TTC in spoiler box
    TTC since 2014
    Unexplained Infertility - but I am 40...Low AMH .30
    7 - IUI (50mg-150mg Clomid) Feb - August 2016 all BFN 
    IVF#1 August 2016 (Antagonist protocol 4/5 eggs) Cancelled cycle :( RE thought I would get at least 10.
    IVF#2 Sept 2016 (microdose luporn pro - disappearing follies, ONLY ONE, convert to IUI) BFN
    IVF#3 November 2016 (4 ER, 3 F,  3DT)-BFP  with TWINS // MC both at almost 10wks  :'( 
    IVF#4 March 2017 //EPP  (10 ER (1 wonky so 9 ER) 7F, 3B (5AB, (2)5BB) PGS tested- ALL abnormal  :'( 
    IVF#5 April 2017 // EPP (7 ER, 7F yes! 6B) 2/5 day 4/6 day - 2 PGS normal! yes!! :)
    IVF#6 May 2017 // Antagonist didn't have time for Estrogen Priming...(4 ER, 3 F, 3B) (5AB, (2) 5BB) 2 PGS normal, yes!! :)
    IVF#7 June 2017 // EPP praying this is it and then on to an FET!

  • @capps42613 It's great to hear of your success and it's awesome of you to stick around here to offer support. :)
    @Hopeful_mom No, I wasn't on progesterone before. As far as I know, my RE hasn't tested my progesterone yet, unless they tested it but didn't tell me the number. Thanks for the reassurance. Learning about this stuff is all really confusing and I wasn't sure if since my AMH was so low, that meant that my clock was ticking too. 
    *TW*
    Me: 31 | DH: 33
    DD1: 8/2014  <3
    TTC #2: 6/2017
    BFP 8/3/2017 | CP 8/4
    BFP 10/16/2017 | CP 10/21
    BFP 12/18/2017 | CP 12/28
    BFP 2/15/2018 | EDD: November 2nd | It's a girl!
    DD2: 10/2018  <3
  • @jenrn1216 You might find this thread very helpful. Hugs
    People think we become mothers when we give birth but the truth is we become mothers the moment we start calling our babies to us in our thoughts, dreams and prayers. Some paths are short and some are so long that you can easily forget where you were headed.

    How I feel all of the time.
    My 7 Year Journey ***Tw in spoiler***
    IVF
    IVF #1 - September 2018; Follistim, Menopur, Cetrotide & Lupron/HCG combo trigger; PGS; ICSI
    Back on Levothyroxine
    FET #1 - October 2018; cancelled, all PGS aneuploid
    FET #1 - November 30th, transferred anyway
    Wondfo BFP 5dp5dt, CB Digi 6dpt, 
    1st Beta on 7dpt 93
    2nd Beta on 10dpt 510!

    TTC #1 since 2011. Tried for 5 years before we knew there was a one year rule.
    Diag w/MS 2016; w/PCOS & IF 2017
    New RE 2018; PCOS diagnosis taken away, IF due to ovary adhesions, but prev. RE insists PCOS IF

    IUI
    IUI #1 July 2017 w/100mg Clo+trigger; BFN; benched w/big cysts
    IUI #2 October 2017 w/50mg Clo+trigger; BFN; benched w/big cysts
    IUI #3 February 2018 w/5mg Femara+trigger; low P
    BFP February; mc March; Subclinical hypothyroid started Levothyroxine 
    IUI #4 March 2018 w/7.5mg Femara+trigger; BFN
    Medicated cycle & TI April 2018 w/7.5mg Femara+trigger; BFN
    Tried several cycles on our own; all BFN
     
  • @hopful_mom- YAY! So glad you are almost at viability! What an exciting time girl :) You got this!!

    @hopefuljj- when do you talk to your RE about your FET plan?

    @ilky- how is the stimming going?


    AFM- I had a bit of a rough Friday (even though I was on the beach!). My nurse emailed me to schedule a follow up call about my ERA results, so I knew it wasn't good. The not knowing what was going on gave me sooo much anxiety. I gave in and emailed my RE who actually emailed me back on a friday evening. Apparently my results was post-receptive, which is attypical according to her. I have never seen anyone on these boards get that result. Most ladies need 12-24 hours MORE of progesterone, not less. So hopefully I can schedule a call this afternoon to go over the results with my RE on the phone. I'm guesssing we are going to have to repeat to make sure I am receptive earlier than normal, since its just such a rare result. Here I was thinking my transfer would be 5 weeks from today... but probably not until April :( can't believe I started the DE last April and I am still not pregnant... This was supposed to give us fast success, but has led to the most heartbreak yet :(
    History in Spoiler

    Age: 32 (same with DH). Together since 2006, Married June 2013 and TTC since August 2015
    Diagnosis: Mild Endo, DOR (AMH of 1.5), Poor Quality Eggs/embryos, Displaced Window of Implantation (ERA Post Receptive)
    March-May 2016: 1 TI and 2 IUIs- BFN 
    June 2016- Laproscopy- found/removed mild endo and confirmed only 1 normal healthy ovary.
    August 2016- IVF #1 with Antagonist Protocol- Cancelled (2 lead follies), converted to IUI- BFN
    Oct-Nov 2016- IVF #2 with Estrogen Priming Micro Lupron Protocol, 2 eggs retrieved, day 3 transfer of 1- BFN
    January 2017- New RE, IVF#3 with Estrogen Priming Antagonist Protocol, 12 eggs, 8 mature, 6 fertilized, 2 day 5 early blasts transferred (none to freeze :(), BFN
    May 2017- Sept 2017- Starting Donor Egg process! Waiting for donor to be available... and then she is pregnant at baseline :(
    Oct 2017- Donor #2: 25R, 22M,18F, 12 blasts frozen! Fresh transfer cancelled due to thin lining with fluid :(
    Nov 2017- Hysterscopy to remove polyp
    Dec 2017- DE FET #1 on 12/8 on 2 perfect blasts- BFN and devastated
    Jan-Mar 2018- ERA #1- Post receptive by 24 hours, ERA #2 RECEPTIVE with 4 days of Progesterone
    Apr 2018- DE FET cancelled for lining issues :(
    Jun 2018- DE FET #2 of two 1AA blasts- first BFP ever! Beta 10dp5dt- 378, Beta 14dp5dt- 2840, Beta 16dp5dt- 4035, beta 18dp5dt- 10916. Due on 2/20 with one baby after a vanishing twin
    Baby Born born early @ 33.5 weeks due to Pre-e
    Back for # 2!
  • Oh no @JamieH2000 I’m so sorry.  It’s just not fair!  Hoping you can get some answers from your RE today and hopefully won’t have to repeat the ERA
  • @JamieH2000 All the creepy internet hugs for you today *hug* I'm so sorry. Hopefully they'll be able to figure out some next steps so that you get success!
    Me: 36 | DH: 35 | Married: 9.17.16
    Diminished ovarian reserve
    BFP: 4/14/2020 EDD: 12/20/2020
  • @jamieh2000 oh gosh! Not news you want to get, let alone whilst away.
    I’m so sorry there’s yet something else. You had so so so many setbacks it’s unbelievable. 
    I did see a few other ladies on other boards who also needed a shorter time, so you’re not alone - just rare and very special  <3

    But! On the other hand what a good job you have done the ERA now to find this out. 
    I’ve just emailed my new Clinic to say I want it on my treatment plan after all ERs but before first FET.
    Me 43 DH 45
    Married 12/2016
    TTC #1 since 04/2015
    AMA, DOR (AMH 0.65, AFC 2-4) and autoimmune issues (RA, APS), low TSH, adenomyosis
    7 retrievals, 3 transfers
    Jun19 FET BFP, due date 7th March 2020, DD born Feb20
    Sep17 IVF1 - 1ER, 1F, 1ET, BFN
    Nov17 IVF2 - 1ER, 0F
    Jan18 IVF3 - 3ER, 1F, 1ET, BFN
    Feb18 - second opinion and additional testing
    Apr18 IVF4 - cancelled (E2 too high)
    May/Jun18 IVF4 - 4ER, 0M, 1F, 1 frozen day 3 (not best quality)
    Jun/Jul18 IVF5 - 5 ER, 3M, 2F, 2 frozen day 3 (not best quality)
    Jul/Aug18 IVF6 - 4ER, 3M, 2F, 2 frozen day 3 (good quality)
    Aug/Sep18 IVF7 - cancelled (cyst)
    Sep/Oct18 IVF7 - 3ER, 3M, 2F, 2 frozen Day 3 (excellent quality)
    Oct18 IVF8 - Cancelled (cyst and too low TSH)
    Oct18-Jan19 bringing TSH under control
    Feb19 ERA and hysteroscopy
    Mar19 Investigation for fibroid and adenomyosis
    Apr19 adenomyosis confirmed, polyps removed
    Jun19 FET after 2 months Lupron, autoimmune protocol, transferred two day 3 frozen embryos
    Sep17 - Pergoveris 10-17 Sep, Orgalutran 15-18 Sep, Ovitrelle 18 Sep, ER 20 Sep for 2 follies, 1 mature egg, fertilized, ET 1x 2d 4-cell embryo 22/09, 05/10 BFN
    Nov17 IVF2 - Pergoveris 2-14 Nov, Orgalutran 5-14 Nov, Ovitrelle 15 Nov, ER 17 Nov for 3 follies, 1 mature egg, did not fertilize
    Jan18 IVF3 - Pergoveris 30 Dec - 8 Jan, Orgalutran 5-8 Jan, Ovitrelle 9 Jan, ER 11 Jan 3 eggs, 2 mature, 1 fertilized, ET 1x 4d 12-cell embryo 15/01, 24/01 BFN
    May/Jun18 IVF4 - Rekovelle 25-29 May, Menogon 30May - 2Jun, Zomacton 25 27 29 31 May and 2Jun, Cetrotide 30May - 3Jun, Gonasi 3Jun, ER 5Jun 4 eggs, none mature, two matured overnight, 1 fertilized with ICSI, Frozen day 3 but not good quality
    Jun/Jul18 IVF5 - Rekovelle 21-24 June, Menogon 25Jun-3Jul, Puregon 4-5Jul, Zomacton 21 23 25 27 29 Jun, Cetrotide 25Jun-5Jul, Gonasi 6Jul, ER 8Jul 5 eggs, 3 mature, 2 fertilized with ICSI, 2 frozen day 3 but not good quality
    Jul/Aug18 IVF6 - Rekovelle 26-29 Jul, Menogon 30Jul-7Aug, Buserelin 26Jul-7Aug, Zomacton 26 28 30 Jul 1 3 Aug, Gonasi 7Aug, ER 9Aug 4 eggs, 3 mature, 2 fertilized (normal IVF), 2 frozen day 3 good quality
    Sep/Oct18 IVF7 - Menogon 19-30Sep, Buserelin 19-30Sep, Zomacton 19 21 23 25 27 Sep, Ovitrelle 1 Oct, ER 3 eggs, 3 mature, 2 fertilized with ICSI, 2 frozen day 3 excellent quality 

    Fav Quote: The greatest thing you'll ever learn is just to love and be loved in return

  • @emmasemm- I mean I feel dramatic sometimes on here.. but it really seems there is always just something for me.. apparently not one step of this is going to go smoothly for me. Do you remember if those other girls repeated the ERA or just transferred 1 day earlier? Obviously I don't want to wait a month and pay another $850, but I also reallyyyy don't want another negative. I can't talk to my RE until Wed, so just trying to be patient until I can talk to her. Part of me wonders if this is the same in my natural cycles and this is why I have never gotten any sort of positive in 2.5 years of trying and treatment. After all of this, I definitely think an ERA is worth it, especially for those of us with less embryos. its a small cost and time delay to check this.

    @dreamscapes and @adc0417- thank you ladies! I know we are all too familiar with delays and its not the end of the world, but I swear, as soon as i get a date, something happens to delay it! I just have to keep hoping the right time is coming soon for this to work...
    History in Spoiler

    Age: 32 (same with DH). Together since 2006, Married June 2013 and TTC since August 2015
    Diagnosis: Mild Endo, DOR (AMH of 1.5), Poor Quality Eggs/embryos, Displaced Window of Implantation (ERA Post Receptive)
    March-May 2016: 1 TI and 2 IUIs- BFN 
    June 2016- Laproscopy- found/removed mild endo and confirmed only 1 normal healthy ovary.
    August 2016- IVF #1 with Antagonist Protocol- Cancelled (2 lead follies), converted to IUI- BFN
    Oct-Nov 2016- IVF #2 with Estrogen Priming Micro Lupron Protocol, 2 eggs retrieved, day 3 transfer of 1- BFN
    January 2017- New RE, IVF#3 with Estrogen Priming Antagonist Protocol, 12 eggs, 8 mature, 6 fertilized, 2 day 5 early blasts transferred (none to freeze :(), BFN
    May 2017- Sept 2017- Starting Donor Egg process! Waiting for donor to be available... and then she is pregnant at baseline :(
    Oct 2017- Donor #2: 25R, 22M,18F, 12 blasts frozen! Fresh transfer cancelled due to thin lining with fluid :(
    Nov 2017- Hysterscopy to remove polyp
    Dec 2017- DE FET #1 on 12/8 on 2 perfect blasts- BFN and devastated
    Jan-Mar 2018- ERA #1- Post receptive by 24 hours, ERA #2 RECEPTIVE with 4 days of Progesterone
    Apr 2018- DE FET cancelled for lining issues :(
    Jun 2018- DE FET #2 of two 1AA blasts- first BFP ever! Beta 10dp5dt- 378, Beta 14dp5dt- 2840, Beta 16dp5dt- 4035, beta 18dp5dt- 10916. Due on 2/20 with one baby after a vanishing twin
    Baby Born born early @ 33.5 weeks due to Pre-e
    Back for # 2!
  • @JamieH2000 So sorry, it's been one setback after another for you. It is very unfair most times. I hope they can give you clear answers and identify the best way to handle this. When I pray I include all of you guys in my prayers.  :)<3

    AFM, I on day 9 on stims. I increased menopur to two vials last night and started garinelex yesterday. Currently, there are 7 follies growing (yay! more than last time, but still too few :( ). I was just checking my E2 level from yesterday and it was 550. Is it too low for what i assume 7 eggs? I have a lot of discomfort and headache. It seems worse than the previous cycle. I'm going back tomorrow for blood test and ultrasound, but was told ER might be on Friday or Saturday. 
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