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August 2019 FET

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Re: August 2019 FET

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    I have my follow up consult today in 3 hours. So nervous to see what he is going to recommend for this last round. I don't think we will do another one if this one isn't successful. I'm going in there armed with information regarding protocols and ideas to improve my chance for quality embryo's vs. quantity. I'll let everyone know what comes of it. 

    I can't do IUI due to tied tubes, so, unfortunately, my only options are FET's or Fresh Transfers. I am going to ask about both this round and hope that maybe a Fresh will give me a secondary option for a transfer with one retrieval round (so long as I can get near the number eggs I did last time). I still had 15 growing at day 3 last time, so If I get that again and can use 2-3 for a fresh transfer, then maybe still end up with 5-6 blasts, that would be great!!
    Me: 45yo, DH: 47yo
    3 Daughters (singleton @27yo, ID  Di/Di Twins @34yo)
    Protein S Deficiency (Blood Clotting Disorder), MTHFR & VIT D issue 
    5 MC's:  Blighted Ovum-D&C @ 9wks;  Natural MC @ 7wks; Blighted Ovum-D&C @ 9wks; MC boy-D&C @ 9wks & Chem PG in 2019
    Tubes were tied after my Twins (and now I am old). Remarried and want to give my DH a baby!

    IVF#1 OE June 2019 - ER 6/15/19, 24R, 21M, 20F, 7 6DBlasts Frozen for PGS Testing,
    RESULTS of PGS 4 abnormal girls,  2 abnormal boys, 1 indeterminate girl
    FET#1 OE August 23, 2019 (transferring 1 indeterminate girl & 1 abnormal boy) - BFN
    IVF#2 November 15, 2019 - ER 9R, 9M, 6F, 2 5dBlasts (fresh transfer) and 1 6DBlast frozen for PGS Testing,
    FRESH Transfer: November 20, 2019, 2 5-day blasts transferred!! 
    BFP 8dp5dt on 11/27 - 12/2 on FRER, BETA #1 12/2 - 11.93. BETA #2 12/4: 4.41 ~CHEMICAL PG
    ******************Starting Donor Process
    June 2020: Egg Donor Cycle and Fresh Transfer of 1 embryo in Czech Republic - CANCELLED DUE TO COVID19
    October 2020.  Split Cycle at UFC with a friend (Andrea) I met on the Bump who was also supposed to go to Prague too  
    DE Retrieval 9/26/2020, 26R, 24M, 12 split Cycle, 9 Fertilized + 1 "questionable", PRAYING FOR AT LEAST 5 BLASTS
    10/1/2020: 4 5DBlasts (AA, BB, BC, BC), 10/2/2020: 3 6DBlasts (BB, BB, BC) FOR A TOTAL OF: 7 BLASTS!! THANK YOU GOD!!
    PGS RESULTS: 5 NORMALS! DAY 5: AA BOY, BB GIRL, BC BOY / DAY 6: BB GIRL, BC GIRL
    DE FET October 29, 2020 - CANCELED DUE TO FLUID IN LINING
    DE FET November 16th, 2020 (transferring an PGS normal Hatching AA Boy)
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    @ladyp0tter I hope the consult went well. What did they say?
    Me:38 DW:33 
    TTC History in Spoiler ***Trigger Warning*** Losses/Child Mentioned 
    Dx: My wife has no sperm  :D and apparently my embryos aren't as good as they look
    2016

     * April IUI#1 - BFN
     * June IUI#2 - BFN
     * July IUI#3 - CP  :'(
     * Sept IVF#1 - 4 Retrieved & Mature, 4 Blasts.  Fresh Transfer 1  - CP  :'(
     * November FET #1 - Transferred 1 Blast - CP  :'(
    2017 Switched REs - Recurrent loss testing for me - all normal, remaining 2 frosties sent for PGS - both abnormal
     * April/May IVF#2:  9 retrieved, 8 mature, 7 fertilized, 7 blasts!  Sent for testing - 2PGS Normals (0 remaining)
     * November IVF #3 12R, 8M, 6F, 4 blasts! - All 4 PGS normal!
     * November FET# 2 (Transfer a PGS normal from IVF#2) - BFP!!!
    2018 DD born 8/20/18
    2019 5PGS frosties ( 4 remaining)
      * September FET#3 (1PGS normal) - Beta#1: 139.7  Beta#2: 322.6

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    @ladyp0tter, have they mentioned anything to you about doing a mock transfer (ERA) to make sure they're putting the embryo in at the right time. I did a mock transfer in July and found out they were putting my embryos in 1 day early. I needed 6 days of progesterone instead of the normal 5. I would defintely ask about it if you're down to your last embryo. 

    Me: 34  DH: 36

    Married: 6 years

    TTC: 6 years

    Diagnosis: Male Factor

    4 Failed I.U.I's with Clomid in 2017 

    Retreival #1: 12/17= 9 eggs, 6 fertilized, 2 frozen 5dp

    Fresh Transfer #1: 12/17- BFN

    FET #1: 3/18- CP   Beta #1= 30 & Beta #2= 26

    Retreival #2: 6/18= 16 eggs, 10 fertilized, 5 frozen 6dp

    FET #2: 7/18 - M/C at 9 weeks    Beta #1= 229 & Beta #2= 444

    FET #3: scheduled for 12/7/18  M/C at 7 weeks  :'(  Beta #1 = 50, Beta # 2 = 115, Beta #3 = 301

    FET #4:  scheduled for 8/16/19

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    My consult went great. RE was very receptive to all my concerns. We talked through all my research!! He was tired by the end! LOL...

    We will be doing less stim meds (gonal F and menopur) to focus on quality this time and in hopes to avoid a lupron trigger (try to use ovidrel) so that we can attempt both a fresh transfer and then a freeze of any remaining eggs for PGS testing. We talked about IF needed and the fresh doesn't work, that we would do an ERA before using any of the hopefully remaining embryo's that made it to freeze and PGS tested normal. I'm praying for at least 1-2 this time rather than NONE!! 

    I will be doing HGH along with the stims for a week leading up to ER in hopes to improve the quality of the eggs. I think he said 150 Gonal-F and like 75 of menopur. Last time I was 225 for both. 

    We looked at my progesterone at the time of my last ER and it was 1.6 which he said they usually like to see 1.5 or less for a fresh, so if we don't get as many eggs this time (which is our hope so not to worry about OHSS and using Lupron), then it should be less than 1.5 this time and allow for the fresh transfer. We would just pick 2 of the best-looking embryos and hope for the best (although last time, my best-looking embryo ended up with the worst chromosomal issues!!! figures). 

    Thanks for the well wishes ladies!!
    Me: 45yo, DH: 47yo
    3 Daughters (singleton @27yo, ID  Di/Di Twins @34yo)
    Protein S Deficiency (Blood Clotting Disorder), MTHFR & VIT D issue 
    5 MC's:  Blighted Ovum-D&C @ 9wks;  Natural MC @ 7wks; Blighted Ovum-D&C @ 9wks; MC boy-D&C @ 9wks & Chem PG in 2019
    Tubes were tied after my Twins (and now I am old). Remarried and want to give my DH a baby!

    IVF#1 OE June 2019 - ER 6/15/19, 24R, 21M, 20F, 7 6DBlasts Frozen for PGS Testing,
    RESULTS of PGS 4 abnormal girls,  2 abnormal boys, 1 indeterminate girl
    FET#1 OE August 23, 2019 (transferring 1 indeterminate girl & 1 abnormal boy) - BFN
    IVF#2 November 15, 2019 - ER 9R, 9M, 6F, 2 5dBlasts (fresh transfer) and 1 6DBlast frozen for PGS Testing,
    FRESH Transfer: November 20, 2019, 2 5-day blasts transferred!! 
    BFP 8dp5dt on 11/27 - 12/2 on FRER, BETA #1 12/2 - 11.93. BETA #2 12/4: 4.41 ~CHEMICAL PG
    ******************Starting Donor Process
    June 2020: Egg Donor Cycle and Fresh Transfer of 1 embryo in Czech Republic - CANCELLED DUE TO COVID19
    October 2020.  Split Cycle at UFC with a friend (Andrea) I met on the Bump who was also supposed to go to Prague too  
    DE Retrieval 9/26/2020, 26R, 24M, 12 split Cycle, 9 Fertilized + 1 "questionable", PRAYING FOR AT LEAST 5 BLASTS
    10/1/2020: 4 5DBlasts (AA, BB, BC, BC), 10/2/2020: 3 6DBlasts (BB, BB, BC) FOR A TOTAL OF: 7 BLASTS!! THANK YOU GOD!!
    PGS RESULTS: 5 NORMALS! DAY 5: AA BOY, BB GIRL, BC BOY / DAY 6: BB GIRL, BC GIRL
    DE FET October 29, 2020 - CANCELED DUE TO FLUID IN LINING
    DE FET November 16th, 2020 (transferring an PGS normal Hatching AA Boy)
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    @ladyp0tter that's great news. 
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