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IF Testing & Treatment w/o 5.9

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Re: IF Testing & Treatment w/o 5.9

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    kiki047kiki047 member
    @mambo5-2 just make sure that if there are any meds that need to be refrigerated that you take ice packs, etc for the road. 

    TTC History:

    Me: 36  MH: 39, TTC since Dec 2017

    Aug '18: PCOS dx

    Nov '18: MH SA - 19mil

    Dec '18-Mar '19: Letrozole + TI - all BFN

    Apr '19: Letrozole + TI, - BFN.  Repeat SA (27mil) & DNA fragmentation test (17%)

    Aug '19: Letrozole + HCG trigger + IUI + prog supp - BFN (MH: 16mil)

    Sep '19: 2nd IUI, same protocol - BFN (MH: 16mil) 

    Dec '19: IVF #1 w/ICSI, PGT. 5 retrieved, 4 fertilized, 3 blasts, 3 PGT-A normal.

    Mar '20: FET #1, perfect 5AA blast transferred. BFN.

    Sept '20: FET #2, 5BB tsf. 9/18/20 BFP!! EDD: 5/27/21. MMC 11w                                                  

    Feb ‘21: FET #3, last 6BB blast transferred. BFP, EDD 11/2/21. MC 5w3d. 

    May '21: IVF #2 w/ICSI, PGT. 8R, 7M, 6F, 6 blasts - 3AB, 3AB, 3BB, 4BB, 5BB, 6BA. Fresh tsf 5/13/21 - BFN. 

    June '21: PGT-A results = 3 abnormal, 1 low level mosaic. Referred to new REI, had consult with 2nd RE in between. 


    Sept '21: RPL, immune testing normal

    Oct '21: IVF #3 w/IMSI, PGT. 33R, 26M, 23F, 9 blasts (7 day 6, 2 day 7). PGT-A = 5 normal, 1 mosaic

    Dec '21: Positive for endometritis, RX Flagyl & Keflex

    Jan '22: FET #5 - Kitchen sink immune/RIF protocol incl. PRP, intralipids, prednisone, medrol, nivestym, fragmin - CP

    Feb '22: FET #6 - Kitchen sink immune/RIF protocol w/higher doses of pred & fragmin - BFN

    Mar '22: Mock cycle for ERA - cancelled, repeat endometrial biopsy instead. Still positive for endometritis. RX ciprofloxacin & amoxicillin. 

    Apr '22: IVF #4 w/IMSI, PGT. 28R, 23M, 16F, 11 blasts. PGT-A = 6 normal. 

    June '22: FET #7 - Microdose lupron downreg w/kitchen sink immune/RIF protocol - double embryo transfer. BFN.

    July '22: FET #8 - Mini stim w/Puregon + trigger, kitchen sink immune/RIF protocol. BFN. 

    Sep '22: Taking a break

    Dec '22: Attempted abdominal myomectomy, fibroid too close to cervix and major blood vessels. Wasn't removed. 

    Feb '23: FET #9 - Modified natural w/baby asp, HCG trigger, PIO, PRP, Medrol, HCG wash, embryo glue - BFP!! EDD 11/11/23


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    @ kiki047 none of mine are refrigerated, I was super surprised that they weren't, but I get to do a lot of mixing medications. Yay... I will not complain because they were free.
    Spoiler for History 

    Me - 30 DH - 32

    April 2009 - 8+ week MC
    January 2012 - BFP - DS Born 10/21/2012
    May 2013 - BFP - Twins MMC @ 13 weeks D&C
    Oct 2013 -  BFP MC @ 6 weeks
    Dec 2013 -  BFP  DD Born 8/16/14 - Cholestasis at 36+5
    Nov 2016 - BFP MC @ 6 weeks
    Dec 2016 - BFP  DD Born 6/19/17 @ 28+4 Severe Pre-E, IUGR, Cholestasis 
    Nov 2017 - BFP MC @ 6 weeks
    Jan 2017 - BFP MC @ 6 weeks
    Jan 2019 - BFP MC @ 6 weeks
    DH Vasectomy Aug 2019
    Feb 2022 - TTC #4 with IVF - RPL testing
    Protein C and S Deficiency - Blood Thinners for Treatment - Maybe we don't know!
    June 2022 - IVF - 2 embryos - 1 transfered 6/22/22 - Transfer Failed
    July 2022 - FET


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    *lurking* 
    @mambo5-2. Oh I have taken either stims or progesterone shots everywhere-- in the bathroom at 2 different weddings, hotels, parents/friends houses secretly, etc. It's totally fine. Live your life! Also FYI-- the stims come refrigerated, but they just need to be kept under 87 degrees Fahrenheit, so as long as its not super hot they can be left out for a while.
    TTC History
    TTC #1 Sep 2017-Sep 2018 
    BFP 11/30/2017 | MMC 12/31/2017
    BFP 6/22/2018 | CP 6/27/2018
    BFP 10/5/2018 | EDD 6/14/2019
    Baby girl born 6/19/19

    TTC #2 May 2020-November 2021
    BFP 7/18/2020 | MonoDi Twins | MMC 9/10/2020
    BFP 11/7/2020 | CP 11/9/2020
    RE Consult January 2021 | Dx "borderline DOR"/RPL
    IVF with PGT:
    Standard Antagonist:
    ER #1 3/27/2021 7R | 5M | 3F | 2B | 1 PGT-A Normal, 1 low-level mosaic
    ER #2 4/22/2021 10R | 7M | 3F | 2B | 0 normal, 2 aneuploid
    ER #3 5/19/2021 2R | 1M | 0F
    Estrogen Priming Antagonist:
    ER #4 7/10/2021 5R | 4M | 3F | 1B | 1 PGT-A Normal
    Duostim  (Standard Antagonist):
    ER #5 9/22/2021 13R | 11M | 8F | 5B | 2 PGT-A Normal, 1 low-level mosaic, 2 aneuploid
    ER #6 10/9/2021  9R | 6M | 4 F | 1B | 1 aneuploid
    FET #1  11/5/2021 | EDD 7/24/2022
    Baby boy born 7/19/22

    TTC #3 since May 2023 (ntnp)
    IVF Started Fall 2023 (Standard Antagonist)
    ER #7 10/6/2023 | 9R | 6M | 5F | 3B | 2 aneuploid, 1 high-level mosaic
    ER #8 10/31/2023 | 5R | 4M | 3F | 1B | 1 PGT-A Normal
    FET #2 11/27/23 | CP (bHCG = 8)
    FET #3 planned Jan 2024



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    @anniemarie887 argggg I'm glad they found problem and have a plan to put this out of it's misery once and for all,  but why not order an ultrasound/second opinion sooner? This seems like it has dragged out waaay tooo loong. I'm so sorry that you're still dealing with this.
    TTC History:
    Me: 36 H: 40 Married 2015. Together since 2010.
    TTC: Sept 2016-Oct 2017
    BFP Oct 2017. DD born July 2018.
    TTC: March 2020. BFP March 2020
    Due date was Nov 2020
    DS born Sept 2020. DS passed away Nov 2020 due to prematurity and birth trauma.
    TTC: March 2021
    IUI #1 Nov 2021, BFN
    IUI #2 Dec 2021 BFP.  MC Jan 2022
    IUI #3 Aug 2022 BFN
    IUI #4 Sept 2022 BFN
    AMH test came back at .081. Was going to move on to IVF with DE, but have decided not to. Will be leaving it up to the universe now.



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    anniemarie887anniemarie887 member
    edited May 2022
    @bearmomma1 so another d&c was brought up a month ago, and then I had a pretty hefty drop. And a week of bleeding and I think we just hoped this was the “end”. I respect my OB, and I did talk to one of the others in the practice too, and didn’t push about doing anything else. Generally speaking I am a very low interventions person (jokes on me now with all this TTGP and needing apparently all the interventions). I don’t love the idea of getting another one considering January wasn’t that long ago, but we talked through benefits and risks, and she said I should not worry about the short time span between them. 

    Edited spelling. 
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    @anniemarie887 oh man, i feel you so much on that low-interventions jokes-o-me thing. i have also always been reflexively low intervention, which i think mostly makes me want to cry when i look back at my TTGP saga and at basically every single moment at which I had to make a decision and opted conservatively.
    History
    I am doing this on my own. Left ovary and fallopian tube removed due to cyst/necrosis just after birth. Right ovary and tube still purport to function.
    Began TTC in Aug '18 @ age 35
    5 or 6 (or 7?!) cycles using frozen donor sperm, ICI. All BFN
    Mar-Jun '19 IUIs, all BFN
    Began process of referral for RE in spring of '19, blood tests confirm low AMH (.54) but all else is good.
    May '19 HSG shows open tube, but ultrasound suggests fibroids
    MRI in June '19 confirms two large fibroids, one growing through wall of uterus
    In June '19 I move from California to Oregon, disrupting my insurance, referrals, etc. 5 months spent piecing it all back together.
    Nov. '19 attempted myomectomy (vaginal approach) failed. 2nd surgery using laparoscopic method in Jan '20 is successful.
    April '20 --> June '20, natural IUIs, all BFN.
    July? saline ultrasound and bubble test demonstrate open tube
    July '20 clomid cycle cancelled for thin lining
    Aug-Oct, 3 femara cycles, all BFN
    RE referral. While waiting to set up an appointment Nov-Jan,I continue with natural cycles and ICI, using a known donor, BFN...
    Jan '21 more bloodwork, AMH is worse (.30), FSH high albeit not catastrophic at 13.2. hysteroscopy all good. "looks cozy!" says the RE.
    Feb '21, injectables (menopur, novarel), iui, BFN (doc said the frozen donor sperm sample had the "best numbers she'd ever seen!")
    Mar '21, injectables, iui cancelled due to lack of follicles, converted to at home-insem. BFN
    May '21, first IVF round cancelled due to cyst.
    July '21 IVF: standard antagonist. 225menupur/225gonal-f/cetrotide/5000u trigger, AFC 7; 6 days of stims. 8 eggs retrieved, 7 mature, 5 fertilize, 4 made it to blast. 3 are 4AB, 1 is 4BB. PGT-A results all abnormal.
    Oct '21 somewhat improved AMH (.51) and significantly improved FSH (8.9). Maybe it's all the pills I swallow.
    Dec -21, standard antagonist. 225menupur/225gonal-f/cetrotide/5000u trigger, AFC 5; 11 days of stims. retrieval yields 5, 4M, 2 reach day-6 blast (4AB & 4BB). 1 low-level mosaic (chr. 3 deletion), 1 complex abnormal.
    Feb '22 FET (low-level mosaic): CP.
    May '22 egg retrieval, lupron flare protocol. HGH priming for 1 month before stims; md lupron 20/20u daily; menopur 225, follistim 225, 10k trigger after 8 days of stims; AFC 10; 13 retrieved; 10 mature; 8 fertilized. All frozen at 2PN for later thaw, grow, and biopsy.
    July '22 egg retrieval same protocol: 9 days of stims; AFC 8; 10 retrieved, 8 mature, 4 fertilized and frozen.
    Sept '22 ER same protocol: AFC 10; 12 retrieved, 11 mature, 11 fertilized.
    From the 3 retrievals, 7 survived to day 5-6 blastocyst, from which I have 2 normal embryos!
    Jan 20, Fully medicated FET, baby aspirin, dexamethasone, acupuncture, and as much woo as I can stand (which isn't very much). BFN.
    July 23, Natural FET + baby aspirin. BFN.
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    @anniemarie887 yea I understand that completely. I wasn't trying to question your dr or your choices. Just wanting this nightmare to be over for you. I wonder if your week of bleeding was your body trying again to rid the retained tissue, and maybe it got some of it out, but that tiny bit left is being darned stubborn! I hope the d&c gets scheduled asap. 
    @acleverusername ooooooh that’s an interesting idea. I always blamed my 10 years of being on BC for messing up my cycles. 
    TTC History:
    Me: 36 H: 40 Married 2015. Together since 2010.
    TTC: Sept 2016-Oct 2017
    BFP Oct 2017. DD born July 2018.
    TTC: March 2020. BFP March 2020
    Due date was Nov 2020
    DS born Sept 2020. DS passed away Nov 2020 due to prematurity and birth trauma.
    TTC: March 2021
    IUI #1 Nov 2021, BFN
    IUI #2 Dec 2021 BFP.  MC Jan 2022
    IUI #3 Aug 2022 BFN
    IUI #4 Sept 2022 BFN
    AMH test came back at .081. Was going to move on to IVF with DE, but have decided not to. Will be leaving it up to the universe now.



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    My BCP are making me so nauseous. Bleh. I had no issues with BCP when I was a teenager at least not that I remember but I started BCP with a never ending period that made me want to cry at 13, actually I did cry, in the OB's office, during a transvaginal ultrasound to try to figure out what was wrong.  So maybe I was just already feeling awful when I started them then. 
    Spoiler for History 

    Me - 30 DH - 32

    April 2009 - 8+ week MC
    January 2012 - BFP - DS Born 10/21/2012
    May 2013 - BFP - Twins MMC @ 13 weeks D&C
    Oct 2013 -  BFP MC @ 6 weeks
    Dec 2013 -  BFP  DD Born 8/16/14 - Cholestasis at 36+5
    Nov 2016 - BFP MC @ 6 weeks
    Dec 2016 - BFP  DD Born 6/19/17 @ 28+4 Severe Pre-E, IUGR, Cholestasis 
    Nov 2017 - BFP MC @ 6 weeks
    Jan 2017 - BFP MC @ 6 weeks
    Jan 2019 - BFP MC @ 6 weeks
    DH Vasectomy Aug 2019
    Feb 2022 - TTC #4 with IVF - RPL testing
    Protein C and S Deficiency - Blood Thinners for Treatment - Maybe we don't know!
    June 2022 - IVF - 2 embryos - 1 transfered 6/22/22 - Transfer Failed
    July 2022 - FET


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    @mambo5-2 i'm sorry. bcp are the worst. it's prob too late for this switch but in the hopefully unlikely event that you ever have to repeat this process, you might want to ask your RE about using another delivery method? I switched from pills to the nuvaring after i wound up with a cyst last year. nuvaring delivers the hormones via a more direct method. when you swallow a pill, the results, as i understand it, are more systemic. i for one get all kinds of side effects when i take pills, but my only notable side effect on the ring is loss of sex drive.
    History
    I am doing this on my own. Left ovary and fallopian tube removed due to cyst/necrosis just after birth. Right ovary and tube still purport to function.
    Began TTC in Aug '18 @ age 35
    5 or 6 (or 7?!) cycles using frozen donor sperm, ICI. All BFN
    Mar-Jun '19 IUIs, all BFN
    Began process of referral for RE in spring of '19, blood tests confirm low AMH (.54) but all else is good.
    May '19 HSG shows open tube, but ultrasound suggests fibroids
    MRI in June '19 confirms two large fibroids, one growing through wall of uterus
    In June '19 I move from California to Oregon, disrupting my insurance, referrals, etc. 5 months spent piecing it all back together.
    Nov. '19 attempted myomectomy (vaginal approach) failed. 2nd surgery using laparoscopic method in Jan '20 is successful.
    April '20 --> June '20, natural IUIs, all BFN.
    July? saline ultrasound and bubble test demonstrate open tube
    July '20 clomid cycle cancelled for thin lining
    Aug-Oct, 3 femara cycles, all BFN
    RE referral. While waiting to set up an appointment Nov-Jan,I continue with natural cycles and ICI, using a known donor, BFN...
    Jan '21 more bloodwork, AMH is worse (.30), FSH high albeit not catastrophic at 13.2. hysteroscopy all good. "looks cozy!" says the RE.
    Feb '21, injectables (menopur, novarel), iui, BFN (doc said the frozen donor sperm sample had the "best numbers she'd ever seen!")
    Mar '21, injectables, iui cancelled due to lack of follicles, converted to at home-insem. BFN
    May '21, first IVF round cancelled due to cyst.
    July '21 IVF: standard antagonist. 225menupur/225gonal-f/cetrotide/5000u trigger, AFC 7; 6 days of stims. 8 eggs retrieved, 7 mature, 5 fertilize, 4 made it to blast. 3 are 4AB, 1 is 4BB. PGT-A results all abnormal.
    Oct '21 somewhat improved AMH (.51) and significantly improved FSH (8.9). Maybe it's all the pills I swallow.
    Dec -21, standard antagonist. 225menupur/225gonal-f/cetrotide/5000u trigger, AFC 5; 11 days of stims. retrieval yields 5, 4M, 2 reach day-6 blast (4AB & 4BB). 1 low-level mosaic (chr. 3 deletion), 1 complex abnormal.
    Feb '22 FET (low-level mosaic): CP.
    May '22 egg retrieval, lupron flare protocol. HGH priming for 1 month before stims; md lupron 20/20u daily; menopur 225, follistim 225, 10k trigger after 8 days of stims; AFC 10; 13 retrieved; 10 mature; 8 fertilized. All frozen at 2PN for later thaw, grow, and biopsy.
    July '22 egg retrieval same protocol: 9 days of stims; AFC 8; 10 retrieved, 8 mature, 4 fertilized and frozen.
    Sept '22 ER same protocol: AFC 10; 12 retrieved, 11 mature, 11 fertilized.
    From the 3 retrievals, 7 survived to day 5-6 blastocyst, from which I have 2 normal embryos!
    Jan 20, Fully medicated FET, baby aspirin, dexamethasone, acupuncture, and as much woo as I can stand (which isn't very much). BFN.
    July 23, Natural FET + baby aspirin. BFN.
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    anniemarie887anniemarie887 member
    edited May 2022
    welp, d&c is monday. of course that means i will no longer be able to do the RE appt... waiting on a call back to see how long it will take to get back on her calendar. ugh.

    eta: called back, august... let's just say i burst into incoherent tears and was just like i don't even know what to do and hung up on the woman. 
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    kiki047kiki047 member
    Oh @anniemarie887 that is so beyond unfair. I'm so sorry. About all of it. That's beyond ridiculous and they really ought to do better for you. It's not like you planned this FFS.

    TTC History:

    Me: 36  MH: 39, TTC since Dec 2017

    Aug '18: PCOS dx

    Nov '18: MH SA - 19mil

    Dec '18-Mar '19: Letrozole + TI - all BFN

    Apr '19: Letrozole + TI, - BFN.  Repeat SA (27mil) & DNA fragmentation test (17%)

    Aug '19: Letrozole + HCG trigger + IUI + prog supp - BFN (MH: 16mil)

    Sep '19: 2nd IUI, same protocol - BFN (MH: 16mil) 

    Dec '19: IVF #1 w/ICSI, PGT. 5 retrieved, 4 fertilized, 3 blasts, 3 PGT-A normal.

    Mar '20: FET #1, perfect 5AA blast transferred. BFN.

    Sept '20: FET #2, 5BB tsf. 9/18/20 BFP!! EDD: 5/27/21. MMC 11w                                                  

    Feb ‘21: FET #3, last 6BB blast transferred. BFP, EDD 11/2/21. MC 5w3d. 

    May '21: IVF #2 w/ICSI, PGT. 8R, 7M, 6F, 6 blasts - 3AB, 3AB, 3BB, 4BB, 5BB, 6BA. Fresh tsf 5/13/21 - BFN. 

    June '21: PGT-A results = 3 abnormal, 1 low level mosaic. Referred to new REI, had consult with 2nd RE in between. 


    Sept '21: RPL, immune testing normal

    Oct '21: IVF #3 w/IMSI, PGT. 33R, 26M, 23F, 9 blasts (7 day 6, 2 day 7). PGT-A = 5 normal, 1 mosaic

    Dec '21: Positive for endometritis, RX Flagyl & Keflex

    Jan '22: FET #5 - Kitchen sink immune/RIF protocol incl. PRP, intralipids, prednisone, medrol, nivestym, fragmin - CP

    Feb '22: FET #6 - Kitchen sink immune/RIF protocol w/higher doses of pred & fragmin - BFN

    Mar '22: Mock cycle for ERA - cancelled, repeat endometrial biopsy instead. Still positive for endometritis. RX ciprofloxacin & amoxicillin. 

    Apr '22: IVF #4 w/IMSI, PGT. 28R, 23M, 16F, 11 blasts. PGT-A = 6 normal. 

    June '22: FET #7 - Microdose lupron downreg w/kitchen sink immune/RIF protocol - double embryo transfer. BFN.

    July '22: FET #8 - Mini stim w/Puregon + trigger, kitchen sink immune/RIF protocol. BFN. 

    Sep '22: Taking a break

    Dec '22: Attempted abdominal myomectomy, fibroid too close to cervix and major blood vessels. Wasn't removed. 

    Feb '23: FET #9 - Modified natural w/baby asp, HCG trigger, PIO, PRP, Medrol, HCG wash, embryo glue - BFP!! EDD 11/11/23


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    @anniemarie887 sending so many hugs 💕
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    anniemarie887anniemarie887 member
    edited May 2022
    I sent my OB an email asking for a favor since she is close with this RE. I told her yesterday I felt high maintenance, and she laughed and was like absolutely not. So now I am actually being high maintenance, and basically asking her to please fix this. 

    I know everyone is on the brink of burn out, but I also know she has space in her calendar sooner than august. So much of fertility stuff can’t be scheduled out months in advance. Put me in the spot that’s normally for some other appointment, just this one time. 
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    @anniemarie887 I really hope they can fit you in earlier, especially since your OB and the RE are close. Hugs friend.
    TTC History:
    Me: 36 H: 40 Married 2015. Together since 2010.
    TTC: Sept 2016-Oct 2017
    BFP Oct 2017. DD born July 2018.
    TTC: March 2020. BFP March 2020
    Due date was Nov 2020
    DS born Sept 2020. DS passed away Nov 2020 due to prematurity and birth trauma.
    TTC: March 2021
    IUI #1 Nov 2021, BFN
    IUI #2 Dec 2021 BFP.  MC Jan 2022
    IUI #3 Aug 2022 BFN
    IUI #4 Sept 2022 BFN
    AMH test came back at .081. Was going to move on to IVF with DE, but have decided not to. Will be leaving it up to the universe now.



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    @anniemarie887 oh no! I'm so sorry love! They absolutely should have somewhere to slide you in before August, move someone's Thursday appointment to your Monday and give you their Thursday come on something
    Spoiler for History 

    Me - 30 DH - 32

    April 2009 - 8+ week MC
    January 2012 - BFP - DS Born 10/21/2012
    May 2013 - BFP - Twins MMC @ 13 weeks D&C
    Oct 2013 -  BFP MC @ 6 weeks
    Dec 2013 -  BFP  DD Born 8/16/14 - Cholestasis at 36+5
    Nov 2016 - BFP MC @ 6 weeks
    Dec 2016 - BFP  DD Born 6/19/17 @ 28+4 Severe Pre-E, IUGR, Cholestasis 
    Nov 2017 - BFP MC @ 6 weeks
    Jan 2017 - BFP MC @ 6 weeks
    Jan 2019 - BFP MC @ 6 weeks
    DH Vasectomy Aug 2019
    Feb 2022 - TTC #4 with IVF - RPL testing
    Protein C and S Deficiency - Blood Thinners for Treatment - Maybe we don't know!
    June 2022 - IVF - 2 embryos - 1 transfered 6/22/22 - Transfer Failed
    July 2022 - FET


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    @anniemarie887 I heart aches for you. I really hope your OB and pull some strings. In the meanwhile, if you're interested, I can connect you with a friend in MD who started treatment and SD and then switched to CCRM. CCRM is a highly regarded clinic throughout the US, so ... while it might not be the RPL expert that your OB had recommended... it might be worthwhile to consult with them? 

    @bearmomma1 totally get how it's natural to blame BCP (or other reproductive control methods) for wonky cycles. Here's something to consider... when we first having cycles, we definitely aren't taught to figure out what's normal and what's not. We're either told that "it's normal... your body is still adjusting" or "it's teenager hormones" etc. And then we get on birth control and don't come off it until we're ready to start having children. 

    I generally think that Verywell articles are well written and they quote their sources, so check this out: https://www.verywellfamily.com/can-birth-control-harm-fertility-or-cause-infertility-1959939

    @tryingktogku especially relevant to you: 
    Even if a person has a health condition that causes anovulation, the birth control cycle can still make it look like they are having regular menstrual cycles.
    Anyways, if this journey has taught me anything, is that I will be teaching my daughter to learn about their body before going on any contraception so that they're aware of challenges she may face when trying to conceive. But, hey, they a ways away. 
    MY CHART
    TTC History
    TTC#2
    Me: 40.5; MH: 39 | Met 02/2009 | Started Dating 08/2017 | Married 02/02/2020
    TTC #2 ... preparing as of March 2024


    TTC #1
    Me: 36, MH: 34 | Met 02/2009 | Started Dating 08/2017 | Married 02/02/2020
    TTC #1 02/2020 - 07/2022
    2009 | Dx PCOS; likely a misdiagnosis
    07/14/20 | Dx Hashimoto's Thyroditis
    07/21/20 | 1st RE appointment
    07/2120 - 08/20/20 | so much testing; no signs of PCOS
    08/20/20 | Dx Unexplained; AMA
    09/08/20 | IUI #1 Clomid + Trigger + Prometrium | BFN
    09/30/20 | Urology consult; more testing required
    10/2020 | Clomid + OPK + TI + Prometrium | BFN
    10/26/2020 | Starting 2nd IUI cycle, with Letrazole and with a new RE / different clinic
    11/03/2020 | New Dx "poor egg quality"; IUI cancelled in favor of Trigger + TI + Prometrium | BFN
    11/26/2020 | Combo IUI (Clomid + Menopur) + Trigger + Prometrium | BFN
    12/20/2020 | Combo IUI (Clomid + Gonal-F) + Trigger | IUI Cancelled due to thin lining; TI only | BFN
    01/14/2021 | Combo IUI (Letrazole + Menopur) + Trigger | BFN
    02/06/2021 | Switched to a new RE (TEW) ; trying naturally until we complete additional testing 
    03/14/2021 | Hybrid Double IUI, with Zymot (Letrazole, Gonal-F) + Trigger + Endometrin | Ovulated 4 mature eggs but still a BFN ☹️
    04/07/2021 | Natural cycle while we regroup | BFN
    04/09/2021 | Employer announces fertility benefits starting 05/01/2021! | Search for a new doctor who accepts insurance
    05/10/2021 | New RE consult & plan for IVF
    05/13/2021 | Mid-luteal IVF cycle #1 interrupted; had to get cancer genetic screening done to make sure I didn't have the same SDHA gene mutation as MH. 
    06/10/2021 | Aygestin priming IVF cycle #1; opted to Cx after 9 days of stims since only 5-6/12 follicles responded
    07/26/2021 | Attempt #2 at IVF cycle #1 (mid-luteal start): 8 retrieved, 8 MII, 6 fert (1 PN3), 3 Day 5 & 6 blasts: 3AA, 3AA, 6AB; 3 euploid
    08/09/2021 | Rest cycle / unmedicated TTC | Shockingly, a BFP! EDD: 5/25/202 | CP at 4w4d
    09/23/2021 | IVF cycle #2 (mid-luteal start): 14 retrieved, 13 MII, 11 fert, 5 Day 5 & 6 blasts: 2 x 3AA, 2 x 3AB, 3BB; 2 euploid
    11/12/2021 | IVF cycle #3 (mid-luteal start): cancelled due to ovaries being on vacation
    12/20/2021 | Rest cycle / unmedicated TTC + Pregmune Immunology Testing; BFN
    01/22/2022 | Rest cycle / unmedicated TTC + understanding uncovered immunological issues; BFN
    02/18/2022 | Mock transfer cycle! ERA, ReceptivaDx, EMMA/ALICE; start Prednisone to address NK activity
    03/16/2022 | Final, "Hail Mary" super-ovulation + TI cycle before FET; BFP! EDD: 12/21/2022 | MMC 05/08/2022
    05/20/2022 | D&C; recovering... 
    06/21/2022 | Trying naturally until October 2022
    07/21/2022 | BFP! EDD 04/02/2023; 👦🏼 born on 4/5/2023


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    @acleverusername that is a very interesting perspective! My RE diagnosed me with Post-Pill PCOS and said it was due to being on the pill I was on. So when I got my first period when I was like 11 it was super heavy and my mom took me to the doctor and they put me in Diane-35 (it’s a higher dose combo pill NOT recommended for long term use) and I was on it with no withdrawal bleeds (because I was instructed to take it that way) for ten years. And so my RE said I fit the diagnostic criteria for post-pill PCOS but that there is not enough data whether or not the body sorts itself out over time or if it causes the condition for life…. 

    If I am ever blessed to have a daughter one day I would be very hesitant to let her go on BCP knowing you can do FAM and that the PCOS does have a hereditary component! 
  • Options
    @anniemarie887 my heart goes out to you! FX Monday is the last time you’ll have to go through that procedure ever again and you’ll be slotted in for a treatment time before august for sure 

    @mambo5-2  I’m sorry the BCP is making you nauseated! It does that to me too so I usually take it with dinner or before bed and I find that helps! It was doing it on an empty stomach in the am that I think was the issue for me!

  • Options
    @tryingktogku I hope your doctor provided you with some research to back up her claim of “pill induced PCOS.” I can tell you that I’ve looked into PCOS thoroughly because I was diagnosed with PCOS when I was 25. I don’t have to expound how familiar I am with PubMed, as I’m sure my frequent source-citing and quotes from research articles speak for themselves, but I have never once come across anything resembling mention of PCOS caused by prolonged use of PCOS.

    I’m not a doctor, obvi take my statement with a grain of salt. But I’ve also been “mistreated/misdiagnosed” by doctors enough that I don’t take anything they say at face value without asking for evidence-based research to back up what they are diagnosing me with and why. 

    MY CHART
    TTC History
    TTC#2
    Me: 40.5; MH: 39 | Met 02/2009 | Started Dating 08/2017 | Married 02/02/2020
    TTC #2 ... preparing as of March 2024


    TTC #1
    Me: 36, MH: 34 | Met 02/2009 | Started Dating 08/2017 | Married 02/02/2020
    TTC #1 02/2020 - 07/2022
    2009 | Dx PCOS; likely a misdiagnosis
    07/14/20 | Dx Hashimoto's Thyroditis
    07/21/20 | 1st RE appointment
    07/2120 - 08/20/20 | so much testing; no signs of PCOS
    08/20/20 | Dx Unexplained; AMA
    09/08/20 | IUI #1 Clomid + Trigger + Prometrium | BFN
    09/30/20 | Urology consult; more testing required
    10/2020 | Clomid + OPK + TI + Prometrium | BFN
    10/26/2020 | Starting 2nd IUI cycle, with Letrazole and with a new RE / different clinic
    11/03/2020 | New Dx "poor egg quality"; IUI cancelled in favor of Trigger + TI + Prometrium | BFN
    11/26/2020 | Combo IUI (Clomid + Menopur) + Trigger + Prometrium | BFN
    12/20/2020 | Combo IUI (Clomid + Gonal-F) + Trigger | IUI Cancelled due to thin lining; TI only | BFN
    01/14/2021 | Combo IUI (Letrazole + Menopur) + Trigger | BFN
    02/06/2021 | Switched to a new RE (TEW) ; trying naturally until we complete additional testing 
    03/14/2021 | Hybrid Double IUI, with Zymot (Letrazole, Gonal-F) + Trigger + Endometrin | Ovulated 4 mature eggs but still a BFN ☹️
    04/07/2021 | Natural cycle while we regroup | BFN
    04/09/2021 | Employer announces fertility benefits starting 05/01/2021! | Search for a new doctor who accepts insurance
    05/10/2021 | New RE consult & plan for IVF
    05/13/2021 | Mid-luteal IVF cycle #1 interrupted; had to get cancer genetic screening done to make sure I didn't have the same SDHA gene mutation as MH. 
    06/10/2021 | Aygestin priming IVF cycle #1; opted to Cx after 9 days of stims since only 5-6/12 follicles responded
    07/26/2021 | Attempt #2 at IVF cycle #1 (mid-luteal start): 8 retrieved, 8 MII, 6 fert (1 PN3), 3 Day 5 & 6 blasts: 3AA, 3AA, 6AB; 3 euploid
    08/09/2021 | Rest cycle / unmedicated TTC | Shockingly, a BFP! EDD: 5/25/202 | CP at 4w4d
    09/23/2021 | IVF cycle #2 (mid-luteal start): 14 retrieved, 13 MII, 11 fert, 5 Day 5 & 6 blasts: 2 x 3AA, 2 x 3AB, 3BB; 2 euploid
    11/12/2021 | IVF cycle #3 (mid-luteal start): cancelled due to ovaries being on vacation
    12/20/2021 | Rest cycle / unmedicated TTC + Pregmune Immunology Testing; BFN
    01/22/2022 | Rest cycle / unmedicated TTC + understanding uncovered immunological issues; BFN
    02/18/2022 | Mock transfer cycle! ERA, ReceptivaDx, EMMA/ALICE; start Prednisone to address NK activity
    03/16/2022 | Final, "Hail Mary" super-ovulation + TI cycle before FET; BFP! EDD: 12/21/2022 | MMC 05/08/2022
    05/20/2022 | D&C; recovering... 
    06/21/2022 | Trying naturally until October 2022
    07/21/2022 | BFP! EDD 04/02/2023; 👦🏼 born on 4/5/2023


  • Options
    @acleverusername I 100% believe that this was not cause by the pill but rather masked as our healthcare has a bandaid solution for most things (ie oh wow an 11 years old period is lasting far longer and is far heavier than normal let’s give her BCP instead of investigating why this is happening) and instead of getting to the root cause but alas that is my “official diagnosis” and to be frank I take what my clinic says with a grain of salt since they were INSISTENT that I do my progesterone test on CD21 even though according to my OPKS I though I ovulated on CD 20 lol 

    I am grateful for this community for the emotional support but also particularly for individuals like your self who are a wealth of information too! 
  • Options
    @anniemarie887 Oh friend, I would have hysterical cried too. If any one ever deserved to jump the line at the RE, it's you. Finger crossed your OB can work some magic! 
  • Options
    @mambo5-2 lol. You laugh, but I have seriously pissed off a doctor or 2 at my insistence or knowing how things work and how they apply to me. 

    I generally draw the line at table flipping….Mostly because it will be me thrown out of the doctors office.

    @tryingktogku yeah, that’s exactly it… a bandaid explanation just to put something on the books. It makes me SO MAD. I would rather be told “the cause of PCOS is yet unknown” than “BCP caused your PCOS.” 

    @optimistgardener good luck with your stim cycle!!! 
    MY CHART
    TTC History
    TTC#2
    Me: 40.5; MH: 39 | Met 02/2009 | Started Dating 08/2017 | Married 02/02/2020
    TTC #2 ... preparing as of March 2024


    TTC #1
    Me: 36, MH: 34 | Met 02/2009 | Started Dating 08/2017 | Married 02/02/2020
    TTC #1 02/2020 - 07/2022
    2009 | Dx PCOS; likely a misdiagnosis
    07/14/20 | Dx Hashimoto's Thyroditis
    07/21/20 | 1st RE appointment
    07/2120 - 08/20/20 | so much testing; no signs of PCOS
    08/20/20 | Dx Unexplained; AMA
    09/08/20 | IUI #1 Clomid + Trigger + Prometrium | BFN
    09/30/20 | Urology consult; more testing required
    10/2020 | Clomid + OPK + TI + Prometrium | BFN
    10/26/2020 | Starting 2nd IUI cycle, with Letrazole and with a new RE / different clinic
    11/03/2020 | New Dx "poor egg quality"; IUI cancelled in favor of Trigger + TI + Prometrium | BFN
    11/26/2020 | Combo IUI (Clomid + Menopur) + Trigger + Prometrium | BFN
    12/20/2020 | Combo IUI (Clomid + Gonal-F) + Trigger | IUI Cancelled due to thin lining; TI only | BFN
    01/14/2021 | Combo IUI (Letrazole + Menopur) + Trigger | BFN
    02/06/2021 | Switched to a new RE (TEW) ; trying naturally until we complete additional testing 
    03/14/2021 | Hybrid Double IUI, with Zymot (Letrazole, Gonal-F) + Trigger + Endometrin | Ovulated 4 mature eggs but still a BFN ☹️
    04/07/2021 | Natural cycle while we regroup | BFN
    04/09/2021 | Employer announces fertility benefits starting 05/01/2021! | Search for a new doctor who accepts insurance
    05/10/2021 | New RE consult & plan for IVF
    05/13/2021 | Mid-luteal IVF cycle #1 interrupted; had to get cancer genetic screening done to make sure I didn't have the same SDHA gene mutation as MH. 
    06/10/2021 | Aygestin priming IVF cycle #1; opted to Cx after 9 days of stims since only 5-6/12 follicles responded
    07/26/2021 | Attempt #2 at IVF cycle #1 (mid-luteal start): 8 retrieved, 8 MII, 6 fert (1 PN3), 3 Day 5 & 6 blasts: 3AA, 3AA, 6AB; 3 euploid
    08/09/2021 | Rest cycle / unmedicated TTC | Shockingly, a BFP! EDD: 5/25/202 | CP at 4w4d
    09/23/2021 | IVF cycle #2 (mid-luteal start): 14 retrieved, 13 MII, 11 fert, 5 Day 5 & 6 blasts: 2 x 3AA, 2 x 3AB, 3BB; 2 euploid
    11/12/2021 | IVF cycle #3 (mid-luteal start): cancelled due to ovaries being on vacation
    12/20/2021 | Rest cycle / unmedicated TTC + Pregmune Immunology Testing; BFN
    01/22/2022 | Rest cycle / unmedicated TTC + understanding uncovered immunological issues; BFN
    02/18/2022 | Mock transfer cycle! ERA, ReceptivaDx, EMMA/ALICE; start Prednisone to address NK activity
    03/16/2022 | Final, "Hail Mary" super-ovulation + TI cycle before FET; BFP! EDD: 12/21/2022 | MMC 05/08/2022
    05/20/2022 | D&C; recovering... 
    06/21/2022 | Trying naturally until October 2022
    07/21/2022 | BFP! EDD 04/02/2023; 👦🏼 born on 4/5/2023


  • Options
    @acleverusername I have also made many doctors mad, I have told doctors to at least test me for something.  That I tested positive for. 
    Spoiler for History 

    Me - 30 DH - 32

    April 2009 - 8+ week MC
    January 2012 - BFP - DS Born 10/21/2012
    May 2013 - BFP - Twins MMC @ 13 weeks D&C
    Oct 2013 -  BFP MC @ 6 weeks
    Dec 2013 -  BFP  DD Born 8/16/14 - Cholestasis at 36+5
    Nov 2016 - BFP MC @ 6 weeks
    Dec 2016 - BFP  DD Born 6/19/17 @ 28+4 Severe Pre-E, IUGR, Cholestasis 
    Nov 2017 - BFP MC @ 6 weeks
    Jan 2017 - BFP MC @ 6 weeks
    Jan 2019 - BFP MC @ 6 weeks
    DH Vasectomy Aug 2019
    Feb 2022 - TTC #4 with IVF - RPL testing
    Protein C and S Deficiency - Blood Thinners for Treatment - Maybe we don't know!
    June 2022 - IVF - 2 embryos - 1 transfered 6/22/22 - Transfer Failed
    July 2022 - FET


  • Options
    In case someone needs a laugh, came across this while browsing R e d d i t 's IF sub: 

    MY CHART
    TTC History
    TTC#2
    Me: 40.5; MH: 39 | Met 02/2009 | Started Dating 08/2017 | Married 02/02/2020
    TTC #2 ... preparing as of March 2024


    TTC #1
    Me: 36, MH: 34 | Met 02/2009 | Started Dating 08/2017 | Married 02/02/2020
    TTC #1 02/2020 - 07/2022
    2009 | Dx PCOS; likely a misdiagnosis
    07/14/20 | Dx Hashimoto's Thyroditis
    07/21/20 | 1st RE appointment
    07/2120 - 08/20/20 | so much testing; no signs of PCOS
    08/20/20 | Dx Unexplained; AMA
    09/08/20 | IUI #1 Clomid + Trigger + Prometrium | BFN
    09/30/20 | Urology consult; more testing required
    10/2020 | Clomid + OPK + TI + Prometrium | BFN
    10/26/2020 | Starting 2nd IUI cycle, with Letrazole and with a new RE / different clinic
    11/03/2020 | New Dx "poor egg quality"; IUI cancelled in favor of Trigger + TI + Prometrium | BFN
    11/26/2020 | Combo IUI (Clomid + Menopur) + Trigger + Prometrium | BFN
    12/20/2020 | Combo IUI (Clomid + Gonal-F) + Trigger | IUI Cancelled due to thin lining; TI only | BFN
    01/14/2021 | Combo IUI (Letrazole + Menopur) + Trigger | BFN
    02/06/2021 | Switched to a new RE (TEW) ; trying naturally until we complete additional testing 
    03/14/2021 | Hybrid Double IUI, with Zymot (Letrazole, Gonal-F) + Trigger + Endometrin | Ovulated 4 mature eggs but still a BFN ☹️
    04/07/2021 | Natural cycle while we regroup | BFN
    04/09/2021 | Employer announces fertility benefits starting 05/01/2021! | Search for a new doctor who accepts insurance
    05/10/2021 | New RE consult & plan for IVF
    05/13/2021 | Mid-luteal IVF cycle #1 interrupted; had to get cancer genetic screening done to make sure I didn't have the same SDHA gene mutation as MH. 
    06/10/2021 | Aygestin priming IVF cycle #1; opted to Cx after 9 days of stims since only 5-6/12 follicles responded
    07/26/2021 | Attempt #2 at IVF cycle #1 (mid-luteal start): 8 retrieved, 8 MII, 6 fert (1 PN3), 3 Day 5 & 6 blasts: 3AA, 3AA, 6AB; 3 euploid
    08/09/2021 | Rest cycle / unmedicated TTC | Shockingly, a BFP! EDD: 5/25/202 | CP at 4w4d
    09/23/2021 | IVF cycle #2 (mid-luteal start): 14 retrieved, 13 MII, 11 fert, 5 Day 5 & 6 blasts: 2 x 3AA, 2 x 3AB, 3BB; 2 euploid
    11/12/2021 | IVF cycle #3 (mid-luteal start): cancelled due to ovaries being on vacation
    12/20/2021 | Rest cycle / unmedicated TTC + Pregmune Immunology Testing; BFN
    01/22/2022 | Rest cycle / unmedicated TTC + understanding uncovered immunological issues; BFN
    02/18/2022 | Mock transfer cycle! ERA, ReceptivaDx, EMMA/ALICE; start Prednisone to address NK activity
    03/16/2022 | Final, "Hail Mary" super-ovulation + TI cycle before FET; BFP! EDD: 12/21/2022 | MMC 05/08/2022
    05/20/2022 | D&C; recovering... 
    06/21/2022 | Trying naturally until October 2022
    07/21/2022 | BFP! EDD 04/02/2023; 👦🏼 born on 4/5/2023


  • Options
    @acleverusername omg Dr Big Balls. and the perineum oil! how are all the best ones insane recommendations about the manparts portion of this effort?
    History
    I am doing this on my own. Left ovary and fallopian tube removed due to cyst/necrosis just after birth. Right ovary and tube still purport to function.
    Began TTC in Aug '18 @ age 35
    5 or 6 (or 7?!) cycles using frozen donor sperm, ICI. All BFN
    Mar-Jun '19 IUIs, all BFN
    Began process of referral for RE in spring of '19, blood tests confirm low AMH (.54) but all else is good.
    May '19 HSG shows open tube, but ultrasound suggests fibroids
    MRI in June '19 confirms two large fibroids, one growing through wall of uterus
    In June '19 I move from California to Oregon, disrupting my insurance, referrals, etc. 5 months spent piecing it all back together.
    Nov. '19 attempted myomectomy (vaginal approach) failed. 2nd surgery using laparoscopic method in Jan '20 is successful.
    April '20 --> June '20, natural IUIs, all BFN.
    July? saline ultrasound and bubble test demonstrate open tube
    July '20 clomid cycle cancelled for thin lining
    Aug-Oct, 3 femara cycles, all BFN
    RE referral. While waiting to set up an appointment Nov-Jan,I continue with natural cycles and ICI, using a known donor, BFN...
    Jan '21 more bloodwork, AMH is worse (.30), FSH high albeit not catastrophic at 13.2. hysteroscopy all good. "looks cozy!" says the RE.
    Feb '21, injectables (menopur, novarel), iui, BFN (doc said the frozen donor sperm sample had the "best numbers she'd ever seen!")
    Mar '21, injectables, iui cancelled due to lack of follicles, converted to at home-insem. BFN
    May '21, first IVF round cancelled due to cyst.
    July '21 IVF: standard antagonist. 225menupur/225gonal-f/cetrotide/5000u trigger, AFC 7; 6 days of stims. 8 eggs retrieved, 7 mature, 5 fertilize, 4 made it to blast. 3 are 4AB, 1 is 4BB. PGT-A results all abnormal.
    Oct '21 somewhat improved AMH (.51) and significantly improved FSH (8.9). Maybe it's all the pills I swallow.
    Dec -21, standard antagonist. 225menupur/225gonal-f/cetrotide/5000u trigger, AFC 5; 11 days of stims. retrieval yields 5, 4M, 2 reach day-6 blast (4AB & 4BB). 1 low-level mosaic (chr. 3 deletion), 1 complex abnormal.
    Feb '22 FET (low-level mosaic): CP.
    May '22 egg retrieval, lupron flare protocol. HGH priming for 1 month before stims; md lupron 20/20u daily; menopur 225, follistim 225, 10k trigger after 8 days of stims; AFC 10; 13 retrieved; 10 mature; 8 fertilized. All frozen at 2PN for later thaw, grow, and biopsy.
    July '22 egg retrieval same protocol: 9 days of stims; AFC 8; 10 retrieved, 8 mature, 4 fertilized and frozen.
    Sept '22 ER same protocol: AFC 10; 12 retrieved, 11 mature, 11 fertilized.
    From the 3 retrievals, 7 survived to day 5-6 blastocyst, from which I have 2 normal embryos!
    Jan 20, Fully medicated FET, baby aspirin, dexamethasone, acupuncture, and as much woo as I can stand (which isn't very much). BFN.
    July 23, Natural FET + baby aspirin. BFN.
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