Me: 34 DH: 36 | Together since 2007 | Married July 2016
TTC #1 since 7.2017
Dx: low morph (1%), ANA positive, low decidualization score, high TSH and testosterone, histone antibodies
IUI #1-3 | all BFN
IVF #1 | 6.11.19 | 24R, 17M, 15F, 6B, PGT-A tested - 5 normal, 3 girls & 2 boys
FET #1 | 9.10.19 | BFN "I know you, but we've never met. I'm with you, but I don't know your name"
RPL, Receptiva, & ERA testing | all normal/negative, recommended going on gluten and dairy free diet for next FET
FET #2 | 3.31.20 | Opted to cancelled due to pandemic, continued diet and tried naturally over the summer
2nd Opinion with another RE | 8.20.20 | Not immune to measles (received 1 dose); SA results similar to 2 years ago; decided to move forward with FET #2 redo at start of next cycle
Surprise natural BFP! | 9.22.20 | MC 10.23.20 at 8 weeks
TTCAL naturally | starting 11.22.20
Initial consultation with Reproductive Immunologist | 9.14.21
Decidualization score biopsy | 10.1.21 | abnormal - low score of 1; endometrial scratch recommended and progesterone supplementation
Saline sono | 10.15.21 | normal
Bloodwork | 10.21.21 | high TSH, high testosterone, positive for anti-nuclear antibodies and histone antibodies, high protein S, multiple genetic mutations
BFP! | 11.3.21 | EDD 7.14.22 | biopsy provided same effect as endometrial scratch; added supplemental progesterone and estrogen, prednisone, levothyroxine, and MTX Support to maintain pregnancy
DS born 7.19.22 after induction
TTC #2 begins 6.2023
Consultation with RI | 6.6.23
Saline sono, endometritis biopsy, skin & eye check | all normal
Labs | high TSH, Factor XIII mutation, high %CD56
Follow up | 8.8.23 | prescribed metformin, prednisone, plaquenil, and levothyroxine
Repeat labs after 3 weeks on meds
Follow up | 11.9.23 | Green light!, increase in prednisone, added lovenox
Repeat labs in 8 weeks
Follow up | 1.16.24 | Green light continues
TTC put on pause
TTC #1 since 7.2017
Dx: low morph (1%), ANA positive, low decidualization score, high TSH and testosterone, histone antibodies
IUI #1-3 | all BFN
IVF #1 | 6.11.19 | 24R, 17M, 15F, 6B, PGT-A tested - 5 normal, 3 girls & 2 boys
FET #1 | 9.10.19 | BFN "I know you, but we've never met. I'm with you, but I don't know your name"
RPL, Receptiva, & ERA testing | all normal/negative, recommended going on gluten and dairy free diet for next FET
FET #2 | 3.31.20 | Opted to cancelled due to pandemic, continued diet and tried naturally over the summer
2nd Opinion with another RE | 8.20.20 | Not immune to measles (received 1 dose); SA results similar to 2 years ago; decided to move forward with FET #2 redo at start of next cycle
Surprise natural BFP! | 9.22.20 | MC 10.23.20 at 8 weeks
TTCAL naturally | starting 11.22.20
Initial consultation with Reproductive Immunologist | 9.14.21
Decidualization score biopsy | 10.1.21 | abnormal - low score of 1; endometrial scratch recommended and progesterone supplementation
Saline sono | 10.15.21 | normal
Bloodwork | 10.21.21 | high TSH, high testosterone, positive for anti-nuclear antibodies and histone antibodies, high protein S, multiple genetic mutations
BFP! | 11.3.21 | EDD 7.14.22 | biopsy provided same effect as endometrial scratch; added supplemental progesterone and estrogen, prednisone, levothyroxine, and MTX Support to maintain pregnancy
DS born 7.19.22 after induction
TTC #2 begins 6.2023
Consultation with RI | 6.6.23
Saline sono, endometritis biopsy, skin & eye check | all normal
Labs | high TSH, Factor XIII mutation, high %CD56
Follow up | 8.8.23 | prescribed metformin, prednisone, plaquenil, and levothyroxine
Repeat labs after 3 weeks on meds
Follow up | 11.9.23 | Green light!, increase in prednisone, added lovenox
Repeat labs in 8 weeks
Follow up | 1.16.24 | Green light continues
TTC put on pause
Re: IF Testing and Treatment w/o 10.25
I love apples and love caramel but do not like biting into the caramel apple. Favorite fall treat would be apple cider donuts straight from the farm.
TTC#1 - March 2013
BFP 8/9/13 - EDD 4/14/14 - DS born 4/23/14
TTC#2 November 2015
Dx: Secondary IF June 2016
Medicated IUI cycle#1- Clomid+IUI -1/15/17 -BFN
Break Mid 2017 - Resumed TTC December 2018
"She believed she could so she did..."
Medicated IUI cycle#2- Femara 5mg+IUI 12/22/18 - BFP 1/4/19 - MMC 2/1/19
Saline Sono 3/15/19 - All Clear!
Medicated IUI cycle#3- Femara 7.5mg+IUI 3/28/19-BFN
Medicated IUI cycle#4- Femara 5mg+Gonal F 50iu+IUI 4/27/19- BFP 5/11/19 - MMC 6/12/19 - D&C 6/14/19-
Incomplete M/C Repeat D&C - 7/3/19 -Testing concluded baby was genetically normal
Dx: Unexplained RPL July 2019 - Tested + as carrier for Usher Syndrome & Familial Mediterranean Fever
Saline Sono 8/7/19 - Mostly Clear! All systems go for IVF#1
But will need a repeat Saline Sono between ER and FET
IVF #1 - Antagonist Protocol - 8/17/19
ER#1 8/27/19 - 12R, 6F, 4 biopsied+frozen! (3d5blasts + 1d6blast)- 2 PGS normal embabies!
Saline Sono 9/13/19 - All Clear! Onto FET Prep#1
FET#1 - 4AA -10/4/19 - BFP 10/14/19 - EDD - 6/21/20 -Beta#1-10dp5dt- 379 Beta#2-12dp5dt- 1007 Beta#3-14dp5dt- 2844
DD born 6/15/20
@shortstack930 So glad your transfer went well. Hope you're able to navigate your work stuff during your TWW. Your embryo is beeaautiful!
@acleverusername On the one hand, I'm thankful I had the work thing to keep my mind off of just sitting around wondering what was going on, but it did kick my ass a little. Love the GIF, it perfectly aligns my love for gardening/plants and my life right now!
@optimistgardener I will for sure mention it to him when I talk to him. I know for my first ER they also had to give me some extra because I was squirming and waving my arms around. MH was allowed to actually be there for that one and it slightly traumatized him. I also woke up in the middle of another surgery when I was a kid, so definitely something to keep in mind. No wonder I always feel like sh*t after.
@hanshotfirst77 Thank you! I had lots of downtime yesterday and will be sitting for most of the day today at my desk and in (zoom) meetings. I'm regretting wearing pants though, lol. Glad you were able to get your testing scheduled this week! Yay! That's one step closer to your FET.
TTC History:
Me: 36 MH: 39, TTC since Dec 2017
Aug '18: PCOS dx
Nov '18: MH SA - 19mil
Dec '18-Mar '19: Letrozole + TI - all BFN
Apr '19: Letrozole + TI, - BFN. Repeat SA (27mil) & DNA fragmentation test (17%)
Aug '19: Letrozole + HCG trigger + IUI + prog supp - BFN (MH: 16mil)
Sep '19: 2nd IUI, same protocol - BFN (MH: 16mil)
Dec '19: IVF #1 w/ICSI, PGT. 5 retrieved, 4 fertilized, 3 blasts, 3 PGT-A normal.
Mar '20: FET #1, perfect 5AA blast transferred. BFN.
Sept '20: FET #2, 5BB tsf. 9/18/20 BFP!! EDD: 5/27/21. MMC 11w
Feb ‘21: FET #3, last 6BB blast transferred. BFP, EDD 11/2/21. MC 5w3d.
May '21: IVF #2 w/ICSI, PGT. 8R, 7M, 6F, 6 blasts - 3AB, 3AB, 3BB, 4BB, 5BB, 6BA. Fresh tsf 5/13/21 - BFN.
June '21: PGT-A results = 3 abnormal, 1 low level mosaic. Referred to new REI, had consult with 2nd RE in between.
Sept '21: RPL, immune testing normal
Oct '21: IVF #3 w/IMSI, PGT. 33R, 26M, 23F, 9 blasts (7 day 6, 2 day 7). PGT-A = 5 normal, 1 mosaic
Dec '21: Positive for endometritis, RX Flagyl & Keflex
Jan '22: FET #5 - Kitchen sink immune/RIF protocol incl. PRP, intralipids, prednisone, medrol, nivestym, fragmin - CP
Feb '22: FET #6 - Kitchen sink immune/RIF protocol w/higher doses of pred & fragmin - BFN
Mar '22: Mock cycle for ERA - cancelled, repeat endometrial biopsy instead. Still positive for endometritis. RX ciprofloxacin & amoxicillin.
Apr '22: IVF #4 w/IMSI, PGT. 28R, 23M, 16F, 11 blasts. PGT-A = 6 normal.
June '22: FET #7 - Microdose lupron downreg w/kitchen sink immune/RIF protocol - double embryo transfer. BFN.
July '22: FET #8 - Mini stim w/Puregon + trigger, kitchen sink immune/RIF protocol. BFN.
Sep '22: Taking a break
Dec '22: Attempted abdominal myomectomy, fibroid too close to cervix and major blood vessels. Wasn't removed.
Feb '23: FET #9 - Modified natural w/baby asp, HCG trigger, PIO, PRP, Medrol, HCG wash, embryo glue - BFP!! EDD 11/11/23
Any questions?: NATM. Just over here like:
BFP 11/30/2017 | MMC 12/31/2017
BFP 6/22/2018 | CP 6/27/2018
BFP 10/5/2018 | EDD 6/14/2019
Baby girl born 6/19/19
TTC #2 May 2020-November 2021
BFP 7/18/2020 | MonoDi Twins | MMC 9/10/2020
BFP 11/7/2020 | CP 11/9/2020
RE Consult January 2021 | Dx "borderline DOR"/RPL
IVF with PGT:
Standard Antagonist:
ER #1 3/27/2021 7R | 5M | 3F | 2B | 1 PGT-A Normal, 1 low-level mosaic
ER #2 4/22/2021 10R | 7M | 3F | 2B | 0 normal, 2 aneuploid
ER #3 5/19/2021 2R | 1M | 0F
Estrogen Priming Antagonist:
ER #4 7/10/2021 5R | 4M | 3F | 1B | 1 PGT-A Normal
Duostim (Standard Antagonist):
ER #5 9/22/2021 13R | 11M | 8F | 5B | 2 PGT-A Normal, 1 low-level mosaic, 2 aneuploid
ER #6 10/9/2021 9R | 6M | 4 F | 1B | 1 aneuploid
FET #1 11/5/2021 | EDD 7/24/2022
Baby boy born 7/19/22
TTC #3 since May 2023 (ntnp)
IVF Started Fall 2023 (Standard Antagonist)
ER #7 10/6/2023 | 9R | 6M | 5F | 3B | 2 aneuploid, 1 high-level mosaic
ER #8 10/31/2023 | 5R | 4M | 3F | 1B | 1 PGT-A Normal
FET #2 11/27/23 | CP (bHCG = 8)
FET #3 planned Jan 2024
@kiki047 I'm so glad the ER went well and you're feeling better!!!
Married 07/2012
DD born 07/2014
DD2 born 10/2018
DS born 10/2022
IF history:
TTC #2 since January 2016
June-Aug 2017: 3 IUIs w/Clomid = BFN
Sept 2017: Dx w/Endometriosis
Oct 2017: IUI w/Letrozole = BFN
Nov 2017: IUI w/Letrozole = BFN
Dec 2017: pre-IVF testing
Jan-Feb 2018: IVF--17 eggs retrieved, 13 fertilized, 9 frozen and 1 transferred on 2/10 = BFP on 2/19!!! EDD 10/29/2018
FET Oct 2021: BFP on 10/31! MC at 5 weeks
FET Feb 2022: BFP on 2/15! EDD 10/29/22
@shortstack930 ooh nice to have those 5 days off, but oof about nights. That's brutal. Are your duties on nights any different from days, in that it might be a little less physically demanding?
Diagnosis (if you've been): PCOS, RPL/RIF, MFI
How are things going?: Great! I waited to do my update until I got the call with our Day 3 results, and they just called. Spoilering for an interesting (good) plot twist:
Well, by some miracle today we now have 23 (!!) that are in contention. I asked how that could possibly happen, did some of them split?! I guess of the 26 that were fertilized, only 18 were dividing by the time they called us in the morning on Saturday but 5 of the 8 that hadn't really done anything at that point have now caught up. I asked if they had any insights on whether those slow ones were any less viable than the others and she couldn't really say, just that the big question is how many will make it to blastocyst. I'm floored. Like completely flabbergasted. I was not expecting to have more than we started with, and am counting my lucky stars right now because I know this is not the norm. We're still bracing ourselves for a drop-off between now and our Day 5 update but this is about as good as it gets and for that I am so very grateful. Please kindly stop me before I go dive down a rabbit hole of googling what this means...
I'm also feeling rather sheepish because I know we have a large percentage of DOR/AMA ladies here right now so I want to be mindful of that.
Any questions?: Lots, but none that we have answers to right now I don't think. My main question is whether or not I should be pushing ahead with another ER right away without knowing the PGT results from this one... I don't want to assume that we can still end up with 12 euploid embyros from a single cycle so my gut is telling me to just do another one anyway. Next update isn't until Thursday, unless something happens between now and then.
Also, can anyone else can see our siggies? They've disappeared for me.
TTC History:
Me: 36 MH: 39, TTC since Dec 2017
Aug '18: PCOS dx
Nov '18: MH SA - 19mil
Dec '18-Mar '19: Letrozole + TI - all BFN
Apr '19: Letrozole + TI, - BFN. Repeat SA (27mil) & DNA fragmentation test (17%)
Aug '19: Letrozole + HCG trigger + IUI + prog supp - BFN (MH: 16mil)
Sep '19: 2nd IUI, same protocol - BFN (MH: 16mil)
Dec '19: IVF #1 w/ICSI, PGT. 5 retrieved, 4 fertilized, 3 blasts, 3 PGT-A normal.
Mar '20: FET #1, perfect 5AA blast transferred. BFN.
Sept '20: FET #2, 5BB tsf. 9/18/20 BFP!! EDD: 5/27/21. MMC 11w
Feb ‘21: FET #3, last 6BB blast transferred. BFP, EDD 11/2/21. MC 5w3d.
May '21: IVF #2 w/ICSI, PGT. 8R, 7M, 6F, 6 blasts - 3AB, 3AB, 3BB, 4BB, 5BB, 6BA. Fresh tsf 5/13/21 - BFN.
June '21: PGT-A results = 3 abnormal, 1 low level mosaic. Referred to new REI, had consult with 2nd RE in between.
Sept '21: RPL, immune testing normal
Oct '21: IVF #3 w/IMSI, PGT. 33R, 26M, 23F, 9 blasts (7 day 6, 2 day 7). PGT-A = 5 normal, 1 mosaic
Dec '21: Positive for endometritis, RX Flagyl & Keflex
Jan '22: FET #5 - Kitchen sink immune/RIF protocol incl. PRP, intralipids, prednisone, medrol, nivestym, fragmin - CP
Feb '22: FET #6 - Kitchen sink immune/RIF protocol w/higher doses of pred & fragmin - BFN
Mar '22: Mock cycle for ERA - cancelled, repeat endometrial biopsy instead. Still positive for endometritis. RX ciprofloxacin & amoxicillin.
Apr '22: IVF #4 w/IMSI, PGT. 28R, 23M, 16F, 11 blasts. PGT-A = 6 normal.
June '22: FET #7 - Microdose lupron downreg w/kitchen sink immune/RIF protocol - double embryo transfer. BFN.
July '22: FET #8 - Mini stim w/Puregon + trigger, kitchen sink immune/RIF protocol. BFN.
Sep '22: Taking a break
Dec '22: Attempted abdominal myomectomy, fibroid too close to cervix and major blood vessels. Wasn't removed.
Feb '23: FET #9 - Modified natural w/baby asp, HCG trigger, PIO, PRP, Medrol, HCG wash, embryo glue - BFP!! EDD 11/11/23
@kiki047 I'm sad I haven't seen Big Hero 6 when I heard that was such a good movie. Such an accurate gif though haha. Hoping you get a good day 3 update today!
@bumblebee0210 lol your gif! I can't believe the time is finally here for you to transfer one of your embryos! So hard not to be anxious. I remember being very emotional to finally reach the day of our transfer. We had done so much to get to that point. Oh the feelings
@shortstack930 would decaf trick your brain into thinking it's getting a caffeine boost? Stay strong this week working nights!
Diagnosis (if you've been): unexplained, low morph, exploring possible immune related diagnosis
TTC #1 since 7.2017
Dx: low morph (1%), ANA positive, low decidualization score, high TSH and testosterone, histone antibodies
IUI #1-3 | all BFN
IVF #1 | 6.11.19 | 24R, 17M, 15F, 6B, PGT-A tested - 5 normal, 3 girls & 2 boys
FET #1 | 9.10.19 | BFN "I know you, but we've never met. I'm with you, but I don't know your name"
RPL, Receptiva, & ERA testing | all normal/negative, recommended going on gluten and dairy free diet for next FET
FET #2 | 3.31.20 | Opted to cancelled due to pandemic, continued diet and tried naturally over the summer
2nd Opinion with another RE | 8.20.20 | Not immune to measles (received 1 dose); SA results similar to 2 years ago; decided to move forward with FET #2 redo at start of next cycle
Surprise natural BFP! | 9.22.20 | MC 10.23.20 at 8 weeks
TTCAL naturally | starting 11.22.20
Initial consultation with Reproductive Immunologist | 9.14.21
Decidualization score biopsy | 10.1.21 | abnormal - low score of 1; endometrial scratch recommended and progesterone supplementation
Saline sono | 10.15.21 | normal
Bloodwork | 10.21.21 | high TSH, high testosterone, positive for anti-nuclear antibodies and histone antibodies, high protein S, multiple genetic mutations
BFP! | 11.3.21 | EDD 7.14.22 | biopsy provided same effect as endometrial scratch; added supplemental progesterone and estrogen, prednisone, levothyroxine, and MTX Support to maintain pregnancy
DS born 7.19.22 after induction
TTC #2 begins 6.2023
Consultation with RI | 6.6.23
Saline sono, endometritis biopsy, skin & eye check | all normal
Labs | high TSH, Factor XIII mutation, high %CD56
Follow up | 8.8.23 | prescribed metformin, prednisone, plaquenil, and levothyroxine
Repeat labs after 3 weeks on meds
Follow up | 11.9.23 | Green light!, increase in prednisone, added lovenox
Repeat labs in 8 weeks
Follow up | 1.16.24 | Green light continues
TTC put on pause
BFP 11/30/2017 | MMC 12/31/2017
BFP 6/22/2018 | CP 6/27/2018
BFP 10/5/2018 | EDD 6/14/2019
Baby girl born 6/19/19
TTC #2 May 2020-November 2021
BFP 7/18/2020 | MonoDi Twins | MMC 9/10/2020
BFP 11/7/2020 | CP 11/9/2020
RE Consult January 2021 | Dx "borderline DOR"/RPL
IVF with PGT:
Standard Antagonist:
ER #1 3/27/2021 7R | 5M | 3F | 2B | 1 PGT-A Normal, 1 low-level mosaic
ER #2 4/22/2021 10R | 7M | 3F | 2B | 0 normal, 2 aneuploid
ER #3 5/19/2021 2R | 1M | 0F
Estrogen Priming Antagonist:
ER #4 7/10/2021 5R | 4M | 3F | 1B | 1 PGT-A Normal
Duostim (Standard Antagonist):
ER #5 9/22/2021 13R | 11M | 8F | 5B | 2 PGT-A Normal, 1 low-level mosaic, 2 aneuploid
ER #6 10/9/2021 9R | 6M | 4 F | 1B | 1 aneuploid
FET #1 11/5/2021 | EDD 7/24/2022
Baby boy born 7/19/22
TTC #3 since May 2023 (ntnp)
IVF Started Fall 2023 (Standard Antagonist)
ER #7 10/6/2023 | 9R | 6M | 5F | 3B | 2 aneuploid, 1 high-level mosaic
ER #8 10/31/2023 | 5R | 4M | 3F | 1B | 1 PGT-A Normal
FET #2 11/27/23 | CP (bHCG = 8)
FET #3 planned Jan 2024
TTC #1 since 7.2017
Dx: low morph (1%), ANA positive, low decidualization score, high TSH and testosterone, histone antibodies
IUI #1-3 | all BFN
IVF #1 | 6.11.19 | 24R, 17M, 15F, 6B, PGT-A tested - 5 normal, 3 girls & 2 boys
FET #1 | 9.10.19 | BFN "I know you, but we've never met. I'm with you, but I don't know your name"
RPL, Receptiva, & ERA testing | all normal/negative, recommended going on gluten and dairy free diet for next FET
FET #2 | 3.31.20 | Opted to cancelled due to pandemic, continued diet and tried naturally over the summer
2nd Opinion with another RE | 8.20.20 | Not immune to measles (received 1 dose); SA results similar to 2 years ago; decided to move forward with FET #2 redo at start of next cycle
Surprise natural BFP! | 9.22.20 | MC 10.23.20 at 8 weeks
TTCAL naturally | starting 11.22.20
Initial consultation with Reproductive Immunologist | 9.14.21
Decidualization score biopsy | 10.1.21 | abnormal - low score of 1; endometrial scratch recommended and progesterone supplementation
Saline sono | 10.15.21 | normal
Bloodwork | 10.21.21 | high TSH, high testosterone, positive for anti-nuclear antibodies and histone antibodies, high protein S, multiple genetic mutations
BFP! | 11.3.21 | EDD 7.14.22 | biopsy provided same effect as endometrial scratch; added supplemental progesterone and estrogen, prednisone, levothyroxine, and MTX Support to maintain pregnancy
DS born 7.19.22 after induction
TTC #2 begins 6.2023
Consultation with RI | 6.6.23
Saline sono, endometritis biopsy, skin & eye check | all normal
Labs | high TSH, Factor XIII mutation, high %CD56
Follow up | 8.8.23 | prescribed metformin, prednisone, plaquenil, and levothyroxine
Repeat labs after 3 weeks on meds
Follow up | 11.9.23 | Green light!, increase in prednisone, added lovenox
Repeat labs in 8 weeks
Follow up | 1.16.24 | Green light continues
TTC put on pause
BFP 11/30/2017 | MMC 12/31/2017
BFP 6/22/2018 | CP 6/27/2018
BFP 10/5/2018 | EDD 6/14/2019
Baby girl born 6/19/19
TTC #2 May 2020-November 2021
BFP 7/18/2020 | MonoDi Twins | MMC 9/10/2020
BFP 11/7/2020 | CP 11/9/2020
RE Consult January 2021 | Dx "borderline DOR"/RPL
IVF with PGT:
Standard Antagonist:
ER #1 3/27/2021 7R | 5M | 3F | 2B | 1 PGT-A Normal, 1 low-level mosaic
ER #2 4/22/2021 10R | 7M | 3F | 2B | 0 normal, 2 aneuploid
ER #3 5/19/2021 2R | 1M | 0F
Estrogen Priming Antagonist:
ER #4 7/10/2021 5R | 4M | 3F | 1B | 1 PGT-A Normal
Duostim (Standard Antagonist):
ER #5 9/22/2021 13R | 11M | 8F | 5B | 2 PGT-A Normal, 1 low-level mosaic, 2 aneuploid
ER #6 10/9/2021 9R | 6M | 4 F | 1B | 1 aneuploid
FET #1 11/5/2021 | EDD 7/24/2022
Baby boy born 7/19/22
TTC #3 since May 2023 (ntnp)
IVF Started Fall 2023 (Standard Antagonist)
ER #7 10/6/2023 | 9R | 6M | 5F | 3B | 2 aneuploid, 1 high-level mosaic
ER #8 10/31/2023 | 5R | 4M | 3F | 1B | 1 PGT-A Normal
FET #2 11/27/23 | CP (bHCG = 8)
FET #3 planned Jan 2024
@shortstack930 are you waiting til beta to test?
@inthewoods23 lol it was a lot. Like I want to say about 15. I just looked at them and was like wow that’s a lot of blood. And she was like I promise we left you some lol 😂
TW I’m glad you got such good response to your loss anniversary that can be tough but sometimes it really does help to be able to talk about it.
I felt really weird and kinda got some traumatic flashbacks when they did an ultrasound I wasn’t expecting today. It was just to check my ovaries which looked fine, very PCOS-y as usual. But idk I didn’t expect to feel so triggered.
TTC#1 - March 2013
BFP 8/9/13 - EDD 4/14/14 - DS born 4/23/14
TTC#2 November 2015
Dx: Secondary IF June 2016
Medicated IUI cycle#1- Clomid+IUI -1/15/17 -BFN
Break Mid 2017 - Resumed TTC December 2018
"She believed she could so she did..."
Medicated IUI cycle#2- Femara 5mg+IUI 12/22/18 - BFP 1/4/19 - MMC 2/1/19
Saline Sono 3/15/19 - All Clear!
Medicated IUI cycle#3- Femara 7.5mg+IUI 3/28/19-BFN
Medicated IUI cycle#4- Femara 5mg+Gonal F 50iu+IUI 4/27/19- BFP 5/11/19 - MMC 6/12/19 - D&C 6/14/19-
Incomplete M/C Repeat D&C - 7/3/19 -Testing concluded baby was genetically normal
Dx: Unexplained RPL July 2019 - Tested + as carrier for Usher Syndrome & Familial Mediterranean Fever
Saline Sono 8/7/19 - Mostly Clear! All systems go for IVF#1
But will need a repeat Saline Sono between ER and FET
IVF #1 - Antagonist Protocol - 8/17/19
ER#1 8/27/19 - 12R, 6F, 4 biopsied+frozen! (3d5blasts + 1d6blast)- 2 PGS normal embabies!
Saline Sono 9/13/19 - All Clear! Onto FET Prep#1
FET#1 - 4AA -10/4/19 - BFP 10/14/19 - EDD - 6/21/20 -Beta#1-10dp5dt- 379 Beta#2-12dp5dt- 1007 Beta#3-14dp5dt- 2844
DD born 6/15/20
@inthewoods23 I picked up some half caff coffee to see if that helps but I might switch to decaf eventually. Yikes about the blood draw! I've had that happen to me before and it's awful.
@hanshotfirst77 I'm debating on if I want to test the day before (Halloween) since DH and I will both be home to see the results together. I'm sorry you got triggered by the u/s. When I first went back to the RE this time I had a wave of flashbacks right away that immediately gave me anxiety, which I totally did not expect. I hope you're able to do something for yourself today to take your mind off of things.
Married 07/2012
DD born 07/2014
DD2 born 10/2018
DS born 10/2022
IF history:
TTC #2 since January 2016
June-Aug 2017: 3 IUIs w/Clomid = BFN
Sept 2017: Dx w/Endometriosis
Oct 2017: IUI w/Letrozole = BFN
Nov 2017: IUI w/Letrozole = BFN
Dec 2017: pre-IVF testing
Jan-Feb 2018: IVF--17 eggs retrieved, 13 fertilized, 9 frozen and 1 transferred on 2/10 = BFP on 2/19!!! EDD 10/29/2018
FET Oct 2021: BFP on 10/31! MC at 5 weeks
FET Feb 2022: BFP on 2/15! EDD 10/29/22
@hanshotfirst77 I hope they left you some blood! Sometimes getting 2 vials from me is a struggle, not looking forward to next months tests
@bumblebee0210 thinking thick for you!
@shortstack930 Glad you got some time off after your transfer! Maybe a switch up in schedule will help the time pass.
@inthewoods23 I hate when they dig the needle around. My clinic has bruised me at every.single.draw. it's the worst.
Diagnosis (if you've been): AMA, DOR, low morph
Sorry I’ve been so absent here lately! Coming back with an actual update today! But first, tags.
@hanshotfirst77 FX for good and speedy results! And totally agreed about cider donuts! Yummm!
@kiki047 that’s so amazing about your ER!! And those numbers are awesome! I’m so excited for you!
@bumblebee0210 sending you all the good vibes for your transfer next week!! Hopefully you’re able to relax and de-stress and take the pressure off yourself (which I know is way easier said than done).
@shortstack930 that’s awesome that your schedule works out so nicely after your transfer!
@inthewoods23 I’m glad you were able to open about your loss and got good responses. I’m definitely someone that finds it freeing to talk openly about my IF and losses.
@walkawaynee no advice about the amusement park. That sounds really fun though! Hopefully you’re able to go.
@inthewoods23 I'm still totally shocked too. I kind of hope that our Day 5 update is perfectly drama-free and will be channeling all of my "good vibes only" juju from here on out.
@hanshotfirst77 that's where I'm at too, like talk about putting all your eggs in one basket lol. There's no way. I'm expecting my next cycle to start anywhere from 7-10 days post-ER so sometime this weekend or next week. At least by that time I'll know how many we have to test.
@shortstack930 thank you!! We're planning on doing back to back embryo banking with the hopes of having around 12 euploid embryos before we start transferring any. Since all of our siggies are missing, *TW* we've now done 3 transfers of euploid embryos resulting in 1 implantation failure and 2 miscarriages at 11w and 5w2d, and 1 failed fresh transfer of a non-tested embryo. The rest of our embryos from that second ER were either abnormal or mosaic, which is why we're banking more now before we even think about any more FETs. We only got 3 blasts from the first round (all euploid), and 6 from the second (2 untested, 3 abnormal, 1 low level mosaic).
@walkawaynee ooh that's a tough one about theme parks. I know for me, I had my ER on Friday and was completely out of commission for the next 24hours, and still pretty sore and uncomfortable on the Sunday. I'm only just starting to feel less tender and bloated today, but I noticed my spotting is back so I'm still actively bleeding which says to me that I'm still not healed internally from them digging around in there for eggs. If it was closer to the end of the week, like 5-7 days later I don't think it would be a problem but then of course there's any risk of OHSS which you won't know how that'll affect you until it happens. Then again, some people feel perfectly fine after.
TTC History:
Me: 36 MH: 39, TTC since Dec 2017
Aug '18: PCOS dx
Nov '18: MH SA - 19mil
Dec '18-Mar '19: Letrozole + TI - all BFN
Apr '19: Letrozole + TI, - BFN. Repeat SA (27mil) & DNA fragmentation test (17%)
Aug '19: Letrozole + HCG trigger + IUI + prog supp - BFN (MH: 16mil)
Sep '19: 2nd IUI, same protocol - BFN (MH: 16mil)
Dec '19: IVF #1 w/ICSI, PGT. 5 retrieved, 4 fertilized, 3 blasts, 3 PGT-A normal.
Mar '20: FET #1, perfect 5AA blast transferred. BFN.
Sept '20: FET #2, 5BB tsf. 9/18/20 BFP!! EDD: 5/27/21. MMC 11w
Feb ‘21: FET #3, last 6BB blast transferred. BFP, EDD 11/2/21. MC 5w3d.
May '21: IVF #2 w/ICSI, PGT. 8R, 7M, 6F, 6 blasts - 3AB, 3AB, 3BB, 4BB, 5BB, 6BA. Fresh tsf 5/13/21 - BFN.
June '21: PGT-A results = 3 abnormal, 1 low level mosaic. Referred to new REI, had consult with 2nd RE in between.
Sept '21: RPL, immune testing normal
Oct '21: IVF #3 w/IMSI, PGT. 33R, 26M, 23F, 9 blasts (7 day 6, 2 day 7). PGT-A = 5 normal, 1 mosaic
Dec '21: Positive for endometritis, RX Flagyl & Keflex
Jan '22: FET #5 - Kitchen sink immune/RIF protocol incl. PRP, intralipids, prednisone, medrol, nivestym, fragmin - CP
Feb '22: FET #6 - Kitchen sink immune/RIF protocol w/higher doses of pred & fragmin - BFN
Mar '22: Mock cycle for ERA - cancelled, repeat endometrial biopsy instead. Still positive for endometritis. RX ciprofloxacin & amoxicillin.
Apr '22: IVF #4 w/IMSI, PGT. 28R, 23M, 16F, 11 blasts. PGT-A = 6 normal.
June '22: FET #7 - Microdose lupron downreg w/kitchen sink immune/RIF protocol - double embryo transfer. BFN.
July '22: FET #8 - Mini stim w/Puregon + trigger, kitchen sink immune/RIF protocol. BFN.
Sep '22: Taking a break
Dec '22: Attempted abdominal myomectomy, fibroid too close to cervix and major blood vessels. Wasn't removed.
Feb '23: FET #9 - Modified natural w/baby asp, HCG trigger, PIO, PRP, Medrol, HCG wash, embryo glue - BFP!! EDD 11/11/23
Diagnosis (if you've been): PCOS
Status (WTO/TWW/TTA): WTO
What are you doing this cycle? (Testing? Treatment?): testing
How are things going? Things are great. My consult with my RE was today with I felt like it went really well. I am so grateful for this group and all the knowledge I have gained from being here because I felt like I really understood everything we discussed in my consult and she was impressed with a lot of the questions I was asking. The plan is to do 3-4 more medicated cycles with Letrozole but my RE is adding metformin and Myo-inositol for me and we’ll do lining and follicle monitoring. The nurse called shortly after the appointment and I’m thrilled that they’re letting me do my blood work and baseline US locally. I have that scheduled for next week and then I’ll start Letrozole, despite it being CD 40 right now. Looks like the next step from today is to start metformin.
The plan if the medicated cycles aren’t successful is to look at IUI.
Any questions?: natm
GTKY: What's your favorite topping for a caramel apple? If you're not a fan of caramel apples, then what is your favorite fall treat?
I like caramel and apples dipped in it, but I don’t like the caramel apples on a stick. Cider donuts are definitely a weakness for me.
@walkawaynee IMO, as long as you're feeling well and not in pain you're probably good to go on the trip. Maybe don't ride the really intense rides if you're not 100%. From my experience - I recovered super fast after my ER. Like my dad had no idea when we had greasy burgers at Red Robin for dinner that night that I had just had major surgery 6 hours prior.
TTC #1 since 7.2017
Dx: low morph (1%), ANA positive, low decidualization score, high TSH and testosterone, histone antibodies
IUI #1-3 | all BFN
IVF #1 | 6.11.19 | 24R, 17M, 15F, 6B, PGT-A tested - 5 normal, 3 girls & 2 boys
FET #1 | 9.10.19 | BFN "I know you, but we've never met. I'm with you, but I don't know your name"
RPL, Receptiva, & ERA testing | all normal/negative, recommended going on gluten and dairy free diet for next FET
FET #2 | 3.31.20 | Opted to cancelled due to pandemic, continued diet and tried naturally over the summer
2nd Opinion with another RE | 8.20.20 | Not immune to measles (received 1 dose); SA results similar to 2 years ago; decided to move forward with FET #2 redo at start of next cycle
Surprise natural BFP! | 9.22.20 | MC 10.23.20 at 8 weeks
TTCAL naturally | starting 11.22.20
Initial consultation with Reproductive Immunologist | 9.14.21
Decidualization score biopsy | 10.1.21 | abnormal - low score of 1; endometrial scratch recommended and progesterone supplementation
Saline sono | 10.15.21 | normal
Bloodwork | 10.21.21 | high TSH, high testosterone, positive for anti-nuclear antibodies and histone antibodies, high protein S, multiple genetic mutations
BFP! | 11.3.21 | EDD 7.14.22 | biopsy provided same effect as endometrial scratch; added supplemental progesterone and estrogen, prednisone, levothyroxine, and MTX Support to maintain pregnancy
DS born 7.19.22 after induction
TTC #2 begins 6.2023
Consultation with RI | 6.6.23
Saline sono, endometritis biopsy, skin & eye check | all normal
Labs | high TSH, Factor XIII mutation, high %CD56
Follow up | 8.8.23 | prescribed metformin, prednisone, plaquenil, and levothyroxine
Repeat labs after 3 weeks on meds
Follow up | 11.9.23 | Green light!, increase in prednisone, added lovenox
Repeat labs in 8 weeks
Follow up | 1.16.24 | Green light continues
TTC put on pause
@kiki75 yay for a success last week!!! i hope the bloating is getting better! that baymax gif is perfect haha. glad to hear you still have 23 great ones!!!!! also, i am not seeing siggys as well.
@bumblebee0210 exciting for a tentative transfer soon! the anxiety totally makes sense. hang in there!
@shortstack930 thats nice that you have five days off after the transfer!! relax and rest up! but nights....yucky. hopefully you can get by with little caffeine needed!
@inthewoods23 ugh i hate when they dig in your arm and miss the vein!! im super pale too, so i get the biggest bruises. glad to hear you got support from your fb post though, that is great. and sorry your chart is being garbage!
@walkawaynee im not sure about the amusement park, but i do love me a trip to a theme park! haha. what i would give to be at disneyland right now....
@gingermama29 im glad your meeting with your RE went well and you like the plan you have! it sounds similar to ours - medicated timed intercourse for now. is this your first time taking metformin? if so, just be prepared for some stomach problems, haha.....maybe tmi, but it majorly affects my digestive tract. i have to slowly increase my doses or i just run to the bathroom all day lol
dx: PCOS, hypothroidism tx: timed intercourse with meds (dexa, clomid, letrozole, metformin, trigger shots)
Second TTGP: started meds for first cycle of tx on 10/13/21
@knockupthestock I've had many Baymax moments but this was one of the worst, lol. *TMI* add on the fact that I didn't poop for over 48hrs and I was all sorts of uncomfortable. Yay for triggering soon!
@bumblebee0210@acleverusername@optimistgardener I am paging our resident experts here with this question. I've already emailed the nurse but maybe you can make some more sense of my thought process... so I had some spotting post-ER on Friday and Saturday, which had basically tapered off by Saturday night and was completely gone by Sunday. Have had some mild to moderate cramping, which is manageable with Tylenol as instructed in my discharge papers. But today I have had some discharge, bright red bleeding and cramping that is more in line with what I would expect with a full period. Except that I'm only 3 days post-ER. I was not expecting AF until 7-9 days after. However, I am also on 2.5mg of letrozole which studies have shown to be good to ward off OHSS because of its ability to lower serum E2 levels. So is it reasonable to assume that this is basically a withdrawal bleed from a crash in my hormone levels? *Important to note that I've had spotting through two of my FET prep cycles where my estradiol supplementation wasn't enough to sustain my lining and I've had to double my doses plus add a patch, so it's not unreasonable to think that a sudden crash in E2 levels could make my body think it needs to shed my lining, right?
My main reason of concern isn't because I think I'm bleeding out, but because we had discussed doing back to back banking cycles, so by that definition, would today have been considered my CD1? And if so, isn't it too soon? This question is more for the nurse, who I hope responds to me ASAP.
TTC History:
Me: 36 MH: 39, TTC since Dec 2017
Aug '18: PCOS dx
Nov '18: MH SA - 19mil
Dec '18-Mar '19: Letrozole + TI - all BFN
Apr '19: Letrozole + TI, - BFN. Repeat SA (27mil) & DNA fragmentation test (17%)
Aug '19: Letrozole + HCG trigger + IUI + prog supp - BFN (MH: 16mil)
Sep '19: 2nd IUI, same protocol - BFN (MH: 16mil)
Dec '19: IVF #1 w/ICSI, PGT. 5 retrieved, 4 fertilized, 3 blasts, 3 PGT-A normal.
Mar '20: FET #1, perfect 5AA blast transferred. BFN.
Sept '20: FET #2, 5BB tsf. 9/18/20 BFP!! EDD: 5/27/21. MMC 11w
Feb ‘21: FET #3, last 6BB blast transferred. BFP, EDD 11/2/21. MC 5w3d.
May '21: IVF #2 w/ICSI, PGT. 8R, 7M, 6F, 6 blasts - 3AB, 3AB, 3BB, 4BB, 5BB, 6BA. Fresh tsf 5/13/21 - BFN.
June '21: PGT-A results = 3 abnormal, 1 low level mosaic. Referred to new REI, had consult with 2nd RE in between.
Sept '21: RPL, immune testing normal
Oct '21: IVF #3 w/IMSI, PGT. 33R, 26M, 23F, 9 blasts (7 day 6, 2 day 7). PGT-A = 5 normal, 1 mosaic
Dec '21: Positive for endometritis, RX Flagyl & Keflex
Jan '22: FET #5 - Kitchen sink immune/RIF protocol incl. PRP, intralipids, prednisone, medrol, nivestym, fragmin - CP
Feb '22: FET #6 - Kitchen sink immune/RIF protocol w/higher doses of pred & fragmin - BFN
Mar '22: Mock cycle for ERA - cancelled, repeat endometrial biopsy instead. Still positive for endometritis. RX ciprofloxacin & amoxicillin.
Apr '22: IVF #4 w/IMSI, PGT. 28R, 23M, 16F, 11 blasts. PGT-A = 6 normal.
June '22: FET #7 - Microdose lupron downreg w/kitchen sink immune/RIF protocol - double embryo transfer. BFN.
July '22: FET #8 - Mini stim w/Puregon + trigger, kitchen sink immune/RIF protocol. BFN.
Sep '22: Taking a break
Dec '22: Attempted abdominal myomectomy, fibroid too close to cervix and major blood vessels. Wasn't removed.
Feb '23: FET #9 - Modified natural w/baby asp, HCG trigger, PIO, PRP, Medrol, HCG wash, embryo glue - BFP!! EDD 11/11/23
@shortstack930 you do you, but i'm on team "go ahead and drink a cup of coffee" in case you need permission for small doses of caffeine to get you through the night shift change. that sounds super rough! but i'm glad you got some time off after the transfer.
@inthewoods23 big cheers on your public honesty about this process. I've not been SM honest, but I've definitely been like "oh, you asked me how i've been doing? well here's how I've been doing" honest with friends and family who have made the mistake of asking me how i've been doing, haha. it can be really freeing to put it out there.
@walkawaynee others have already answered the theme park question but my sense is that the difference between 1 day after vs 6 days after is significant. My recovery was pretty minimal because an 8-egg retrieval is not, like, a 33-egg retrieval. more follicles will mean more just, physical damage done in the act of retrieval, plus your body will have to deal with first making space for all them eggs and then retreating back to normal dimensions again... but still, I would not have been very interested in doing any theme park rides for at least 3 or 4 days afterwards. I did not have spotting afterwards, and I was (at least kind of) able to get on a bicycle two days later and ride a couple of miles downtown (but i regretted it a little afterwards). I also managed to get in a car and drive four hours down the freeway a couple of days later. but if I felt basically competent for normal life stuff, I wasn't really up for crazy jostling or tumbly belly stuff. I had some nausea that crept up on me late the day of retrieval when the anti-nausea meds had worn off, and kind of lurked on me for a day or so.
@gingermama29 yay!!! for things are great. so nice when people get to say that and feel that on this board.
@knockupthestock congrats on getting to be done with the dex! do they do a dose reduction thing or do they cut you off all at once?
I feel like @inthewoods23 was just hungry for caramel apples when she wrote this question. Honestly, I love the idea of a caramel apple, but the "in theory" aspect of the thing runs up against the reality that I hate and despise mushy apples, and it seems like caramel apples are always mushy. if it were a perfectly crisp apple, i'd love to do just a simple caramel-only dip (actually dipped slices sounds even better, because the apple to caramel ratio would be better, and the whole thing less messy). But if the apple is not perfectly crisp, well then I guess I'd probably be on team "apple cider donut" with the rest of y'all.
Oct '21 somewhat improved AMH (.51) and significantly improved FSH (8.9). Maybe it's all the pills I swallow.
Dec -21, standard antagonist. 225menupur/225gonal-f/cetrotide/5000u trigger, AFC 5; 11 days of stims. retrieval yields 5, 4M, 2 reach day-6 blast (4AB & 4BB). 1 low-level mosaic (chr. 3 deletion), 1 complex abnormal.
Feb '22 FET (low-level mosaic): CP.
May '22 egg retrieval, lupron flare protocol. HGH priming for 1 month before stims; md lupron 20/20u daily; menopur 225, follistim 225, 10k trigger after 8 days of stims; AFC 10; 13 retrieved; 10 mature; 8 fertilized. All frozen at 2PN for later thaw, grow, and biopsy.
July '22 egg retrieval same protocol: 9 days of stims; AFC 8; 10 retrieved, 8 mature, 4 fertilized and frozen.
Sept '22 ER same protocol: AFC 10; 12 retrieved, 11 mature, 11 fertilized.
From the 3 retrievals, 7 survived to day 5-6 blastocyst, from which I have 2 normal embryos!
Jan 20, Fully medicated FET, baby aspirin, dexamethasone, acupuncture, and as much woo as I can stand (which isn't very much). BFN.
July 23, Natural FET + baby aspirin. BFN.
Oct '21 somewhat improved AMH (.51) and significantly improved FSH (8.9). Maybe it's all the pills I swallow.
Dec -21, standard antagonist. 225menupur/225gonal-f/cetrotide/5000u trigger, AFC 5; 11 days of stims. retrieval yields 5, 4M, 2 reach day-6 blast (4AB & 4BB). 1 low-level mosaic (chr. 3 deletion), 1 complex abnormal.
Feb '22 FET (low-level mosaic): CP.
May '22 egg retrieval, lupron flare protocol. HGH priming for 1 month before stims; md lupron 20/20u daily; menopur 225, follistim 225, 10k trigger after 8 days of stims; AFC 10; 13 retrieved; 10 mature; 8 fertilized. All frozen at 2PN for later thaw, grow, and biopsy.
July '22 egg retrieval same protocol: 9 days of stims; AFC 8; 10 retrieved, 8 mature, 4 fertilized and frozen.
Sept '22 ER same protocol: AFC 10; 12 retrieved, 11 mature, 11 fertilized.
From the 3 retrievals, 7 survived to day 5-6 blastocyst, from which I have 2 normal embryos!
Jan 20, Fully medicated FET, baby aspirin, dexamethasone, acupuncture, and as much woo as I can stand (which isn't very much). BFN.
July 23, Natural FET + baby aspirin. BFN.
@kiki047 I did see one other person around in the Infertility board who did get her period only 4 days after ER so it is possible.
@optimistgardener I made sure not to be really detailed like just said I did a biopsy instead of specifying uterine biopsy. Spared people some of the grosser details lol. Not sure what I would do about the meds. Those gonal-f pens are freaking expensive! I've mentioned this before - my ER we used only 5000 units to keep risk of OHSS down. The original plan had been 10,000. DH and I busted out laughing at your response to the GTKY 🤣. Because that was kind of the case! Not so much a caramel apple (although my mom brought me a 3 pack that I devoured last week) but a regular apple cut up and dipped in peanut butter and honey was what I was hungry for 🤣
TTC #1 since 7.2017
Dx: low morph (1%), ANA positive, low decidualization score, high TSH and testosterone, histone antibodies
IUI #1-3 | all BFN
IVF #1 | 6.11.19 | 24R, 17M, 15F, 6B, PGT-A tested - 5 normal, 3 girls & 2 boys
FET #1 | 9.10.19 | BFN "I know you, but we've never met. I'm with you, but I don't know your name"
RPL, Receptiva, & ERA testing | all normal/negative, recommended going on gluten and dairy free diet for next FET
FET #2 | 3.31.20 | Opted to cancelled due to pandemic, continued diet and tried naturally over the summer
2nd Opinion with another RE | 8.20.20 | Not immune to measles (received 1 dose); SA results similar to 2 years ago; decided to move forward with FET #2 redo at start of next cycle
Surprise natural BFP! | 9.22.20 | MC 10.23.20 at 8 weeks
TTCAL naturally | starting 11.22.20
Initial consultation with Reproductive Immunologist | 9.14.21
Decidualization score biopsy | 10.1.21 | abnormal - low score of 1; endometrial scratch recommended and progesterone supplementation
Saline sono | 10.15.21 | normal
Bloodwork | 10.21.21 | high TSH, high testosterone, positive for anti-nuclear antibodies and histone antibodies, high protein S, multiple genetic mutations
BFP! | 11.3.21 | EDD 7.14.22 | biopsy provided same effect as endometrial scratch; added supplemental progesterone and estrogen, prednisone, levothyroxine, and MTX Support to maintain pregnancy
DS born 7.19.22 after induction
TTC #2 begins 6.2023
Consultation with RI | 6.6.23
Saline sono, endometritis biopsy, skin & eye check | all normal
Labs | high TSH, Factor XIII mutation, high %CD56
Follow up | 8.8.23 | prescribed metformin, prednisone, plaquenil, and levothyroxine
Repeat labs after 3 weeks on meds
Follow up | 11.9.23 | Green light!, increase in prednisone, added lovenox
Repeat labs in 8 weeks
Follow up | 1.16.24 | Green light continues
TTC put on pause
Oct '21 somewhat improved AMH (.51) and significantly improved FSH (8.9). Maybe it's all the pills I swallow.
Dec -21, standard antagonist. 225menupur/225gonal-f/cetrotide/5000u trigger, AFC 5; 11 days of stims. retrieval yields 5, 4M, 2 reach day-6 blast (4AB & 4BB). 1 low-level mosaic (chr. 3 deletion), 1 complex abnormal.
Feb '22 FET (low-level mosaic): CP.
May '22 egg retrieval, lupron flare protocol. HGH priming for 1 month before stims; md lupron 20/20u daily; menopur 225, follistim 225, 10k trigger after 8 days of stims; AFC 10; 13 retrieved; 10 mature; 8 fertilized. All frozen at 2PN for later thaw, grow, and biopsy.
July '22 egg retrieval same protocol: 9 days of stims; AFC 8; 10 retrieved, 8 mature, 4 fertilized and frozen.
Sept '22 ER same protocol: AFC 10; 12 retrieved, 11 mature, 11 fertilized.
From the 3 retrievals, 7 survived to day 5-6 blastocyst, from which I have 2 normal embryos!
Jan 20, Fully medicated FET, baby aspirin, dexamethasone, acupuncture, and as much woo as I can stand (which isn't very much). BFN.
July 23, Natural FET + baby aspirin. BFN.
*flexes* Okay, here goes:
@hanshotfirst77 it's wonderful that you managed to get your testing done! And the SHG lined up! Hopefully it won't be long until you can start treatment.
@kiki047 holy smokes! I hope YH doesn't feel so bad now since it turns out your MII > fert conversation is actually so much better. Here's to hoping that many of them make it to Day 5/6. Crossing everything for you. Btw, I do definitely appreciate your sensitivity about us DOR or DOR-like ladies. I'm really hoping @bumblebee0210 is right that what we lack in egg quality/quantity, we'll make up in uterus awesomeness. As for your Q about have you started your period, you likely did. As I recall, you did a Lupron only trigger? When I cancelled my ER back in June, they had me do a Lupron trigger to "pop" all the follicles, and I got my period 4 days early. The nurse told me that while it's not usual, it's not unexpected when it's a Lupron only trigger.
@bumblebee0210 dude! I CANNOT believe that just like that you're prepping for your transfer and that it's NEXT WEEK! Like WOAH?! Where did the time go? Remember when you were all #BitterHag and saying things like "you'll be back here for your #2 and I'll still doing ER #200." Well, THAT didn't happen! Youppie! Also, once again, can I just pray that your ute is good? Thinking thick for you.
@shortstack930 That's awesome that you ended up with 5 days off after transfer! I feel like that's another sign of planets aligning. Good luck with surviving the night shifts though. Maybe they'll help make the time go by quicker! I'm in favor of you testing on Sunday, but like, I understand if you decide not to. :P My opinion is not important.
@inthewoods23 first of all, the meme for this week's thread is 💯. BRAVO! Also, LOL @optimistgardener finding you out about your GTKY. Hehe. I hope you satisfied your craving. Also, I'm so happy your insurance saga is finally over. What does "I should be on an immune protocol" mean? Are you expecting results back in time for next cycle (if you even need it?) Are you going continue TTC "unassisted" for a while? Also, I'm SO happy that you're feeling some relief about opening up on FB. I'm not brave enough to do that on FB because I have a bunch of FB friends who are from my former Church on it, and Christian Orthodox, like Catholics, do not approve of IVF (more on that later). **TW** I did, however, post something about my CP in a friend Slack group. Mostly because I was raving about the fact that I got the booster shot on Friday, having qualified because of my recent loss. **End TW**
@walkawaynee Others have already weighed in, but my thoughts are the same. Since you're DOR, it's likely that you won't feel like you've been hit by an 18-wheeler after your ER. But it would be nice if the theme park outing is 2+ days after the ER. Also, I hope all the stuff that kept you away last week has sorted itself out.
@gingermama29 HIIIIII! Welcome back. So happy that you had what sounds like an amazing first meeting with your RE! Woot! Your plan going forward sounds excellent. Good luck with that Metformin. By the sounds of it, it's NAS-TAY stuff. Remind me, is IVF an option of your down the road?
@knockupthestock First of all, welcome back to TB's TTGP. I read your post last week about the horrible side-effects of dexamethasone and I cried deep inside. Gah! I hope those side effects go away quickly once you're off of it. I'm also kind of happy to have read about it, since at one point, I was asking my RE to put me on a retrieval protocol that included dexamethasone. It didn't happen in the end, and now I feel like I dodged a bullet. Good luck with all the baby dancing!
@optimistgardener FWIW, if you run out of Gonal-F, I can expedite some I will likely have left over (if you're into that). I know that you're ordering from overseas, so with the shipping delays, this might be an option to consider. I don't actually have experience with lower hCG trigger. Last cycle I had both an hCG trigger + double Lupron trigger (12 hours apart). And I think my hCG amount was only 2500IU. Also, re: your better than normal blood work results, re: FSH at least, I think that it's still the highest one you've gotten that "rules the lot." As you get older, it tends to jump around from month to month. I got all excited when last December 2020, my FSH came back at 6.7 or something like that, after being 9.23 in March 2020. And then in March 2021, it was up to 13. But never mind me, I'm just here, POOPING ON YOUR PARTY!
Phew...I done it! Taking the dog out for a walk now, and then will post my update.
TTC#2
TTC #2 ... preparing as of March 2024
TTC #1
TTC #1 02/2020 - 07/2022
2009 | Dx PCOS; likely a misdiagnosis
07/14/20 | Dx Hashimoto's Thyroditis
07/21/20 | 1st RE appointment
07/2120 - 08/20/20 | so much testing; no signs of PCOS
08/20/20 | Dx Unexplained; AMA
09/08/20 | IUI #1 Clomid + Trigger + Prometrium | BFN
09/30/20 | Urology consult; more testing required
10/2020 | Clomid + OPK + TI + Prometrium | BFN
10/26/2020 | Starting 2nd IUI cycle, with Letrazole and with a new RE / different clinic
11/03/2020 | New Dx "poor egg quality"; IUI cancelled in favor of Trigger + TI + Prometrium | BFN
11/26/2020 | Combo IUI (Clomid + Menopur) + Trigger + Prometrium | BFN
12/20/2020 | Combo IUI (Clomid + Gonal-F) + Trigger | IUI Cancelled due to thin lining; TI only | BFN
01/14/2021 | Combo IUI (Letrazole + Menopur) + Trigger | BFN
02/06/2021 | Switched to a new RE (TEW) ; trying naturally until we complete additional testing
03/14/2021 | Hybrid Double IUI, with Zymot (Letrazole, Gonal-F) + Trigger + Endometrin | Ovulated 4 mature eggs but still a BFN ☹️
04/07/2021 | Natural cycle while we regroup | BFN
04/09/2021 | Employer announces fertility benefits starting 05/01/2021! | Search for a new doctor who accepts insurance
05/10/2021 | New RE consult & plan for IVF
05/13/2021 | Mid-luteal IVF cycle #1 interrupted; had to get cancer genetic screening done to make sure I didn't have the same SDHA gene mutation as MH.
06/10/2021 | Aygestin priming IVF cycle #1; opted to Cx after 9 days of stims since only 5-6/12 follicles responded
07/26/2021 | Attempt #2 at IVF cycle #1 (mid-luteal start): 8 retrieved, 8 MII, 6 fert (1 PN3), 3 Day 5 & 6 blasts: 3AA, 3AA, 6AB; 3 euploid
08/09/2021 | Rest cycle / unmedicated TTC | Shockingly, a BFP! EDD: 5/25/202 | CP at 4w4d
09/23/2021 | IVF cycle #2 (mid-luteal start): 14 retrieved, 13 MII, 11 fert, 5 Day 5 & 6 blasts: 2 x 3AA, 2 x 3AB, 3BB; 2 euploid
11/12/2021 | IVF cycle #3 (mid-luteal start): cancelled due to ovaries being on vacation
12/20/2021 | Rest cycle / unmedicated TTC + Pregmune Immunology Testing; BFN
01/22/2022 | Rest cycle / unmedicated TTC + understanding uncovered immunological issues; BFN
02/18/2022 | Mock transfer cycle! ERA, ReceptivaDx, EMMA/ALICE; start Prednisone to address NK activity
03/16/2022 | Final, "Hail Mary" super-ovulation + TI cycle before FET; BFP! EDD: 12/21/2022 | MMC 05/08/2022
05/20/2022 | D&C; recovering...
06/21/2022 | Trying naturally until October 2022
07/21/2022 | BFP! EDD 04/02/2023; 👦🏼 born on 4/5/2023
I feel like I'm being a bad-forum-friend to @keikilove. I felt so many feels reading your post last week. Yet here I am, not being able to do anything more than just send you virtual support.
Status (WTO/TWW/TTA): technically TWW
What are you doing this cycle? (Testing? Treatment?): SHOTS SHOTS SHOTS SSSSSSHOTS! (a.k.a. stims for ER #2).
How are things going?: You ready for this? I'm gonna spoiler A LOT so brace yourselves.
First of all, I'm sure you'll wondering, but yes, we survived the "atmospheric river" and "bomb cyclone" that hit SF in the last 48 hours. More about the weather in spoiler.
Weather aside, IT'S HERE. My 2nd ER cycle. Looks like a bit of Letrazole did the trick. I went in for my "baseline" on Thursday (in quotes because my coordinator was convinced that my positive OPK from prior Sunday had been a "false positive" since Letrazole tends to do that. And in my mind, yeah OK... I KNOW what a positive OPK looks like and I'm telling you I ovulated. And of course, I had. So, at baseline, I had...
So, today I had my first f/u ultrasound (Day 5) and I remain cautiously optimistic.
I have also managed to eff up my HGH, due to "false confidence" in my ability to execute my shots like I've done it a million times. More on that in spoiler too.
Anyways, I'm back into the clinic on Thursday for another ultrasound/bloodwork, and then again sometime on the weekend, with an ER likely happening Monday-Wednesday next week.
Also, as I mentioned above, I managed to get a Covid booster on Friday. I actually had the least amount of reaction to it, then to the first 2 shots. I'm happy I got that out of the way.
I've also been catching up on my TEW shows, and have some information for you:
@laura-kay, I'm not sure if you're still lurking, but you might want to check this one out:
Finally, last night I read an interesting WaPo article on religious take on IVF. I've been keeping quiet about our IVF journey on FB primarily because I have a lot of ppl from my former parish there, and it's against Orthodoxy to do IVF. It's also against Catholicism. However, this article looked at how ppl of faith are managing, and most are just doing that "in secret". The article also polled people of faith, asking if they considered IVF moral/immoral/not a moral issue and about 80% of Catholics say that it's not a moral issue. As an Orthodox, that's what I think too, but I'm not ready to reconcile my own beliefs with those of my chosen faith just yet. Oh, and also, did you know that Islam permits IVF! I was frankly shocked, but happily so.
Any questions?: How do we feel about nearly-expired/just expired medication? I realized that I have some Ganirelix that expires Oct 26, 2021. This is antagonist (similar to Cetrotide) that I purchased back in Feb when I was still OOP and was "stocking up" on meds. I start my antag on Wed, so the lot I have will have been expired 1 day then, and then +1 each day after. I kind of want to use it, but at the same time, the antagonist isn't something I want to eff with. Thoughts?
GTKY: What's your favorite topping for a caramel apple? If you're not a fan of caramel apples, then what is your favorite fall treat? I don't think I've ever had a caramel apple and I don't think I would want to. I'm not a particularly sweet person, but like @shortstack930 I'll take a homemade pumpkin pie with a gluten free crust. I'm going to try to make a dairy-free pumpkin pie this year. Last year I found a great gluten free crust recipe; this year, I discovered a great coconut yogurt I'll attempt to use in lieu of evaporated milk for the stuffing.
TTC#2
TTC #2 ... preparing as of March 2024
TTC #1
TTC #1 02/2020 - 07/2022
2009 | Dx PCOS; likely a misdiagnosis
07/14/20 | Dx Hashimoto's Thyroditis
07/21/20 | 1st RE appointment
07/2120 - 08/20/20 | so much testing; no signs of PCOS
08/20/20 | Dx Unexplained; AMA
09/08/20 | IUI #1 Clomid + Trigger + Prometrium | BFN
09/30/20 | Urology consult; more testing required
10/2020 | Clomid + OPK + TI + Prometrium | BFN
10/26/2020 | Starting 2nd IUI cycle, with Letrazole and with a new RE / different clinic
11/03/2020 | New Dx "poor egg quality"; IUI cancelled in favor of Trigger + TI + Prometrium | BFN
11/26/2020 | Combo IUI (Clomid + Menopur) + Trigger + Prometrium | BFN
12/20/2020 | Combo IUI (Clomid + Gonal-F) + Trigger | IUI Cancelled due to thin lining; TI only | BFN
01/14/2021 | Combo IUI (Letrazole + Menopur) + Trigger | BFN
02/06/2021 | Switched to a new RE (TEW) ; trying naturally until we complete additional testing
03/14/2021 | Hybrid Double IUI, with Zymot (Letrazole, Gonal-F) + Trigger + Endometrin | Ovulated 4 mature eggs but still a BFN ☹️
04/07/2021 | Natural cycle while we regroup | BFN
04/09/2021 | Employer announces fertility benefits starting 05/01/2021! | Search for a new doctor who accepts insurance
05/10/2021 | New RE consult & plan for IVF
05/13/2021 | Mid-luteal IVF cycle #1 interrupted; had to get cancer genetic screening done to make sure I didn't have the same SDHA gene mutation as MH.
06/10/2021 | Aygestin priming IVF cycle #1; opted to Cx after 9 days of stims since only 5-6/12 follicles responded
07/26/2021 | Attempt #2 at IVF cycle #1 (mid-luteal start): 8 retrieved, 8 MII, 6 fert (1 PN3), 3 Day 5 & 6 blasts: 3AA, 3AA, 6AB; 3 euploid
08/09/2021 | Rest cycle / unmedicated TTC | Shockingly, a BFP! EDD: 5/25/202 | CP at 4w4d
09/23/2021 | IVF cycle #2 (mid-luteal start): 14 retrieved, 13 MII, 11 fert, 5 Day 5 & 6 blasts: 2 x 3AA, 2 x 3AB, 3BB; 2 euploid
11/12/2021 | IVF cycle #3 (mid-luteal start): cancelled due to ovaries being on vacation
12/20/2021 | Rest cycle / unmedicated TTC + Pregmune Immunology Testing; BFN
01/22/2022 | Rest cycle / unmedicated TTC + understanding uncovered immunological issues; BFN
02/18/2022 | Mock transfer cycle! ERA, ReceptivaDx, EMMA/ALICE; start Prednisone to address NK activity
03/16/2022 | Final, "Hail Mary" super-ovulation + TI cycle before FET; BFP! EDD: 12/21/2022 | MMC 05/08/2022
05/20/2022 | D&C; recovering...
06/21/2022 | Trying naturally until October 2022
07/21/2022 | BFP! EDD 04/02/2023; 👦🏼 born on 4/5/2023
@knockupthestock yes this is my first time taking metformin. My RE did warn me about the GI side effects and is easing me into the dosage. I’m starting with 1 pill a day for 2 weeks and then increasing to 2 and then eventually the 3. Yay for follicle growth and triggering! FX for you!
@kiki047 oooh good to know about the timed release option. I’m glad that combo has made a difference for you! Here’s hoping for the same here.
@optimistgardener oh man your ER is going to be here so soon! That annoying little voice is the worst!
@acleverusername yes IVF is definitely an option down the road. I’m incredibly fortunate to have insurance that covers 3 rounds in full. But my RE and I agreed that we’d rather save that option to use if the other treatments don’t work. She’s optimistic about medicated cycles since I’ve gotten KU twice on them. Hopefully monitoring and the added medication will be the difference maker for a THB. Glad everything you’ve gone through in the last few months gave your ovaries the kick in the eggs they needed (love that expression 😂). FX for good growth in your follies for your next appointment! So excited your ER is coming up!
Married 07/2012
DD born 07/2014
DD2 born 10/2018
DS born 10/2022
IF history:
TTC #2 since January 2016
June-Aug 2017: 3 IUIs w/Clomid = BFN
Sept 2017: Dx w/Endometriosis
Oct 2017: IUI w/Letrozole = BFN
Nov 2017: IUI w/Letrozole = BFN
Dec 2017: pre-IVF testing
Jan-Feb 2018: IVF--17 eggs retrieved, 13 fertilized, 9 frozen and 1 transferred on 2/10 = BFP on 2/19!!! EDD 10/29/2018
FET Oct 2021: BFP on 10/31! MC at 5 weeks
FET Feb 2022: BFP on 2/15! EDD 10/29/22
BFP 11/30/2017 | MMC 12/31/2017
BFP 6/22/2018 | CP 6/27/2018
BFP 10/5/2018 | EDD 6/14/2019
Baby girl born 6/19/19
TTC #2 May 2020-November 2021
BFP 7/18/2020 | MonoDi Twins | MMC 9/10/2020
BFP 11/7/2020 | CP 11/9/2020
RE Consult January 2021 | Dx "borderline DOR"/RPL
IVF with PGT:
Standard Antagonist:
ER #1 3/27/2021 7R | 5M | 3F | 2B | 1 PGT-A Normal, 1 low-level mosaic
ER #2 4/22/2021 10R | 7M | 3F | 2B | 0 normal, 2 aneuploid
ER #3 5/19/2021 2R | 1M | 0F
Estrogen Priming Antagonist:
ER #4 7/10/2021 5R | 4M | 3F | 1B | 1 PGT-A Normal
Duostim (Standard Antagonist):
ER #5 9/22/2021 13R | 11M | 8F | 5B | 2 PGT-A Normal, 1 low-level mosaic, 2 aneuploid
ER #6 10/9/2021 9R | 6M | 4 F | 1B | 1 aneuploid
FET #1 11/5/2021 | EDD 7/24/2022
Baby boy born 7/19/22
TTC #3 since May 2023 (ntnp)
IVF Started Fall 2023 (Standard Antagonist)
ER #7 10/6/2023 | 9R | 6M | 5F | 3B | 2 aneuploid, 1 high-level mosaic
ER #8 10/31/2023 | 5R | 4M | 3F | 1B | 1 PGT-A Normal
FET #2 11/27/23 | CP (bHCG = 8)
FET #3 planned Jan 2024
Oct '21 somewhat improved AMH (.51) and significantly improved FSH (8.9). Maybe it's all the pills I swallow.
Dec -21, standard antagonist. 225menupur/225gonal-f/cetrotide/5000u trigger, AFC 5; 11 days of stims. retrieval yields 5, 4M, 2 reach day-6 blast (4AB & 4BB). 1 low-level mosaic (chr. 3 deletion), 1 complex abnormal.
Feb '22 FET (low-level mosaic): CP.
May '22 egg retrieval, lupron flare protocol. HGH priming for 1 month before stims; md lupron 20/20u daily; menopur 225, follistim 225, 10k trigger after 8 days of stims; AFC 10; 13 retrieved; 10 mature; 8 fertilized. All frozen at 2PN for later thaw, grow, and biopsy.
July '22 egg retrieval same protocol: 9 days of stims; AFC 8; 10 retrieved, 8 mature, 4 fertilized and frozen.
Sept '22 ER same protocol: AFC 10; 12 retrieved, 11 mature, 11 fertilized.
From the 3 retrievals, 7 survived to day 5-6 blastocyst, from which I have 2 normal embryos!
Jan 20, Fully medicated FET, baby aspirin, dexamethasone, acupuncture, and as much woo as I can stand (which isn't very much). BFN.
July 23, Natural FET + baby aspirin. BFN.
@bumblebee0210, FX all goes smoothly Thurs and you can pin down a transfer date, and that you get good news on your blast!
@walkawaynee, others have chimed in, but I'll agree and say it depends on how soon after the ER. Mine was 2 days before Thanksgiving and I was so bloated and sore, just moving around my in-laws house and eating was enough for me that day, but by the weekend I was feeling fine. Of course everyone responds differently and you may be totally fine a day later or sooner, but I would plan to be a little sore for at least a couple of days.
Glad the consult went well @gingermama29 and you were able.to develop a plan!
@acleverusername, glad your cycle is going well and I'll be sending you all of the good egg vibes!! Also, after that week, I think some good wine was more than called for!
Diagnosis (if you've been): primarily MFI + ovulatory dysfunction
Other than the quickly approaching FET, nothing interesting. I can't remember who it was now, but a few weeks ago someone mentioned their RE's office not being able to find the uterus/ovaries. Funny enough, the med student sitting in on my lining check couldn't track down my ovaries last week either and even my RE had a hard time finding them. We know the L one is adhered to the back of my uterus, so that one always causes trouble, but I never really thought about my R one before. Given the issues it caused during my ER and its habit of camping out in hard to reach places, I'm starting to wonder if it's not stuck to some ish too.
@acleverusername I never did satisfy that craving yesterday lmao. I will have to today! When I say immune protocol, I mean I'll be put on immunosuppressants based on what my lab work says. As an example - if my immune system is overactive and attacking embryos preventing from them implanting, the immunosuppressants should calm my system down so that it doesn't attack embryos. I'm technically supposed to be TTA but when not even a hint of pregnancy has happened all but 1 time, I think we're very unlikely to end up with a surprise. I think we'll have all our results sometime in next month's cycle but we might not get clearance to start trying in December. I believe the RI usually likes to see how lab work changes after being on the new meds for a few weeks. But yes, we're going to be full steam ahead on trying naturally on this protocol. And if it works, we'll have to start thinking about what to do with our 3 embryos still sitting on ice. Which actually.... some of my family is quite Catholic and very pro-life and I wonder what their opinions would be towards what we do with these embryos. I wonder if they've been secretly judging me for going through IVF. I think we can donate the embryos for science. I'm having a hard time at the idea of putting them up for embryo adoption. Like how freaked out am I going to be with a full biological child out there should I come across them some day. I think you can do these types of adoptions as open, but it might depend on the clinic. We'll cross that bridge when we get to it. And girl you have been through a lot in the past week!
Also....
This talk of IVF and religion is all very interesting. Is there anything specific about it, or does it all fall under the bucket of "you're playing god by doing IVF"? Is this where someone makes the argument that if they think IVF is wrong, then they shouldn't get cancer treatment because it's also medical science?
@zwink1 I expect I will have similar "oh we're already here?" feelings should we get around to doing a round 2 with the RI. IF stuff goes so much faster when you've had success already of course it feels short!
TTC #1 since 7.2017
Dx: low morph (1%), ANA positive, low decidualization score, high TSH and testosterone, histone antibodies
IUI #1-3 | all BFN
IVF #1 | 6.11.19 | 24R, 17M, 15F, 6B, PGT-A tested - 5 normal, 3 girls & 2 boys
FET #1 | 9.10.19 | BFN "I know you, but we've never met. I'm with you, but I don't know your name"
RPL, Receptiva, & ERA testing | all normal/negative, recommended going on gluten and dairy free diet for next FET
FET #2 | 3.31.20 | Opted to cancelled due to pandemic, continued diet and tried naturally over the summer
2nd Opinion with another RE | 8.20.20 | Not immune to measles (received 1 dose); SA results similar to 2 years ago; decided to move forward with FET #2 redo at start of next cycle
Surprise natural BFP! | 9.22.20 | MC 10.23.20 at 8 weeks
TTCAL naturally | starting 11.22.20
Initial consultation with Reproductive Immunologist | 9.14.21
Decidualization score biopsy | 10.1.21 | abnormal - low score of 1; endometrial scratch recommended and progesterone supplementation
Saline sono | 10.15.21 | normal
Bloodwork | 10.21.21 | high TSH, high testosterone, positive for anti-nuclear antibodies and histone antibodies, high protein S, multiple genetic mutations
BFP! | 11.3.21 | EDD 7.14.22 | biopsy provided same effect as endometrial scratch; added supplemental progesterone and estrogen, prednisone, levothyroxine, and MTX Support to maintain pregnancy
DS born 7.19.22 after induction
TTC #2 begins 6.2023
Consultation with RI | 6.6.23
Saline sono, endometritis biopsy, skin & eye check | all normal
Labs | high TSH, Factor XIII mutation, high %CD56
Follow up | 8.8.23 | prescribed metformin, prednisone, plaquenil, and levothyroxine
Repeat labs after 3 weeks on meds
Follow up | 11.9.23 | Green light!, increase in prednisone, added lovenox
Repeat labs in 8 weeks
Follow up | 1.16.24 | Green light continues
TTC put on pause
Islamic belief when it comes to medical interventions are typically quite open-minded, seeing science as part and parcel of the scholarship that humans are enjoined to pursue. There are, of course, exceptions, but it does not follow the same kinds of rules that, say, particularly orthodox or also unusual readings of Christian doctrine might do (Jehovah's Witnesses, etc.).
And FWIW everything I just said here is only relevant for the "mainstream" of Muslim opinion. There will be radicals in every tradition who believe all kinds of 😬🙄🙃 stuff.
Oct '21 somewhat improved AMH (.51) and significantly improved FSH (8.9). Maybe it's all the pills I swallow.
Dec -21, standard antagonist. 225menupur/225gonal-f/cetrotide/5000u trigger, AFC 5; 11 days of stims. retrieval yields 5, 4M, 2 reach day-6 blast (4AB & 4BB). 1 low-level mosaic (chr. 3 deletion), 1 complex abnormal.
Feb '22 FET (low-level mosaic): CP.
May '22 egg retrieval, lupron flare protocol. HGH priming for 1 month before stims; md lupron 20/20u daily; menopur 225, follistim 225, 10k trigger after 8 days of stims; AFC 10; 13 retrieved; 10 mature; 8 fertilized. All frozen at 2PN for later thaw, grow, and biopsy.
July '22 egg retrieval same protocol: 9 days of stims; AFC 8; 10 retrieved, 8 mature, 4 fertilized and frozen.
Sept '22 ER same protocol: AFC 10; 12 retrieved, 11 mature, 11 fertilized.
From the 3 retrievals, 7 survived to day 5-6 blastocyst, from which I have 2 normal embryos!
Jan 20, Fully medicated FET, baby aspirin, dexamethasone, acupuncture, and as much woo as I can stand (which isn't very much). BFN.
July 23, Natural FET + baby aspirin. BFN.
@gingermama29 yep that sounds familiar
TTC #1 since 7.2017
Dx: low morph (1%), ANA positive, low decidualization score, high TSH and testosterone, histone antibodies
IUI #1-3 | all BFN
IVF #1 | 6.11.19 | 24R, 17M, 15F, 6B, PGT-A tested - 5 normal, 3 girls & 2 boys
FET #1 | 9.10.19 | BFN "I know you, but we've never met. I'm with you, but I don't know your name"
RPL, Receptiva, & ERA testing | all normal/negative, recommended going on gluten and dairy free diet for next FET
FET #2 | 3.31.20 | Opted to cancelled due to pandemic, continued diet and tried naturally over the summer
2nd Opinion with another RE | 8.20.20 | Not immune to measles (received 1 dose); SA results similar to 2 years ago; decided to move forward with FET #2 redo at start of next cycle
Surprise natural BFP! | 9.22.20 | MC 10.23.20 at 8 weeks
TTCAL naturally | starting 11.22.20
Initial consultation with Reproductive Immunologist | 9.14.21
Decidualization score biopsy | 10.1.21 | abnormal - low score of 1; endometrial scratch recommended and progesterone supplementation
Saline sono | 10.15.21 | normal
Bloodwork | 10.21.21 | high TSH, high testosterone, positive for anti-nuclear antibodies and histone antibodies, high protein S, multiple genetic mutations
BFP! | 11.3.21 | EDD 7.14.22 | biopsy provided same effect as endometrial scratch; added supplemental progesterone and estrogen, prednisone, levothyroxine, and MTX Support to maintain pregnancy
DS born 7.19.22 after induction
TTC #2 begins 6.2023
Consultation with RI | 6.6.23
Saline sono, endometritis biopsy, skin & eye check | all normal
Labs | high TSH, Factor XIII mutation, high %CD56
Follow up | 8.8.23 | prescribed metformin, prednisone, plaquenil, and levothyroxine
Repeat labs after 3 weeks on meds
Follow up | 11.9.23 | Green light!, increase in prednisone, added lovenox
Repeat labs in 8 weeks
Follow up | 1.16.24 | Green light continues
TTC put on pause
@walkawaynee as others have said, right after my ER I was not feeling great. So I’d probably plan on wanting to rest for a few days after.
@zwink1 Good luck with your upcoming FET! So many of us are so close or getting there. Super exciting!
@acleverusername Good luck with your next ER! Hope those follies keep growing!
I also find this IVF and religion stuff kind of fascinating. I am not a very religious person. Raised Jewish and Catholic but mostly just as in celebrate the holidays. It never really factored in to my decision making when it came to my IF and RPL but I can understand how it could be for others. But I did have the feeling of wanting to give all my embryos a chance.
anyways my nurse called and my levels look good. Onward to SHG on Friday.
TTC#1 - March 2013
BFP 8/9/13 - EDD 4/14/14 - DS born 4/23/14
TTC#2 November 2015
Dx: Secondary IF June 2016
Medicated IUI cycle#1- Clomid+IUI -1/15/17 -BFN
Break Mid 2017 - Resumed TTC December 2018
"She believed she could so she did..."
Medicated IUI cycle#2- Femara 5mg+IUI 12/22/18 - BFP 1/4/19 - MMC 2/1/19
Saline Sono 3/15/19 - All Clear!
Medicated IUI cycle#3- Femara 7.5mg+IUI 3/28/19-BFN
Medicated IUI cycle#4- Femara 5mg+Gonal F 50iu+IUI 4/27/19- BFP 5/11/19 - MMC 6/12/19 - D&C 6/14/19-
Incomplete M/C Repeat D&C - 7/3/19 -Testing concluded baby was genetically normal
Dx: Unexplained RPL July 2019 - Tested + as carrier for Usher Syndrome & Familial Mediterranean Fever
Saline Sono 8/7/19 - Mostly Clear! All systems go for IVF#1
But will need a repeat Saline Sono between ER and FET
IVF #1 - Antagonist Protocol - 8/17/19
ER#1 8/27/19 - 12R, 6F, 4 biopsied+frozen! (3d5blasts + 1d6blast)- 2 PGS normal embabies!
Saline Sono 9/13/19 - All Clear! Onto FET Prep#1
FET#1 - 4AA -10/4/19 - BFP 10/14/19 - EDD - 6/21/20 -Beta#1-10dp5dt- 379 Beta#2-12dp5dt- 1007 Beta#3-14dp5dt- 2844
DD born 6/15/20
BFP 11/30/2017 | MMC 12/31/2017
BFP 6/22/2018 | CP 6/27/2018
BFP 10/5/2018 | EDD 6/14/2019
Baby girl born 6/19/19
TTC #2 May 2020-November 2021
BFP 7/18/2020 | MonoDi Twins | MMC 9/10/2020
BFP 11/7/2020 | CP 11/9/2020
RE Consult January 2021 | Dx "borderline DOR"/RPL
IVF with PGT:
Standard Antagonist:
ER #1 3/27/2021 7R | 5M | 3F | 2B | 1 PGT-A Normal, 1 low-level mosaic
ER #2 4/22/2021 10R | 7M | 3F | 2B | 0 normal, 2 aneuploid
ER #3 5/19/2021 2R | 1M | 0F
Estrogen Priming Antagonist:
ER #4 7/10/2021 5R | 4M | 3F | 1B | 1 PGT-A Normal
Duostim (Standard Antagonist):
ER #5 9/22/2021 13R | 11M | 8F | 5B | 2 PGT-A Normal, 1 low-level mosaic, 2 aneuploid
ER #6 10/9/2021 9R | 6M | 4 F | 1B | 1 aneuploid
FET #1 11/5/2021 | EDD 7/24/2022
Baby boy born 7/19/22
TTC #3 since May 2023 (ntnp)
IVF Started Fall 2023 (Standard Antagonist)
ER #7 10/6/2023 | 9R | 6M | 5F | 3B | 2 aneuploid, 1 high-level mosaic
ER #8 10/31/2023 | 5R | 4M | 3F | 1B | 1 PGT-A Normal
FET #2 11/27/23 | CP (bHCG = 8)
FET #3 planned Jan 2024
Also, I'm pretty sure I got Godsmacked: I lost my cross this morning, after posting this last night. Now, I kind of set myself up for that loss... I took off my cross for my massage on Sunday and put it into an unsecured pocket in my handbag.... and I sometimes don't zip up my handbag. So yeah... I was asking for it, but the timing is quite ironic.
TTC#2
TTC #2 ... preparing as of March 2024
TTC #1
TTC #1 02/2020 - 07/2022
2009 | Dx PCOS; likely a misdiagnosis
07/14/20 | Dx Hashimoto's Thyroditis
07/21/20 | 1st RE appointment
07/2120 - 08/20/20 | so much testing; no signs of PCOS
08/20/20 | Dx Unexplained; AMA
09/08/20 | IUI #1 Clomid + Trigger + Prometrium | BFN
09/30/20 | Urology consult; more testing required
10/2020 | Clomid + OPK + TI + Prometrium | BFN
10/26/2020 | Starting 2nd IUI cycle, with Letrazole and with a new RE / different clinic
11/03/2020 | New Dx "poor egg quality"; IUI cancelled in favor of Trigger + TI + Prometrium | BFN
11/26/2020 | Combo IUI (Clomid + Menopur) + Trigger + Prometrium | BFN
12/20/2020 | Combo IUI (Clomid + Gonal-F) + Trigger | IUI Cancelled due to thin lining; TI only | BFN
01/14/2021 | Combo IUI (Letrazole + Menopur) + Trigger | BFN
02/06/2021 | Switched to a new RE (TEW) ; trying naturally until we complete additional testing
03/14/2021 | Hybrid Double IUI, with Zymot (Letrazole, Gonal-F) + Trigger + Endometrin | Ovulated 4 mature eggs but still a BFN ☹️
04/07/2021 | Natural cycle while we regroup | BFN
04/09/2021 | Employer announces fertility benefits starting 05/01/2021! | Search for a new doctor who accepts insurance
05/10/2021 | New RE consult & plan for IVF
05/13/2021 | Mid-luteal IVF cycle #1 interrupted; had to get cancer genetic screening done to make sure I didn't have the same SDHA gene mutation as MH.
06/10/2021 | Aygestin priming IVF cycle #1; opted to Cx after 9 days of stims since only 5-6/12 follicles responded
07/26/2021 | Attempt #2 at IVF cycle #1 (mid-luteal start): 8 retrieved, 8 MII, 6 fert (1 PN3), 3 Day 5 & 6 blasts: 3AA, 3AA, 6AB; 3 euploid
08/09/2021 | Rest cycle / unmedicated TTC | Shockingly, a BFP! EDD: 5/25/202 | CP at 4w4d
09/23/2021 | IVF cycle #2 (mid-luteal start): 14 retrieved, 13 MII, 11 fert, 5 Day 5 & 6 blasts: 2 x 3AA, 2 x 3AB, 3BB; 2 euploid
11/12/2021 | IVF cycle #3 (mid-luteal start): cancelled due to ovaries being on vacation
12/20/2021 | Rest cycle / unmedicated TTC + Pregmune Immunology Testing; BFN
01/22/2022 | Rest cycle / unmedicated TTC + understanding uncovered immunological issues; BFN
02/18/2022 | Mock transfer cycle! ERA, ReceptivaDx, EMMA/ALICE; start Prednisone to address NK activity
03/16/2022 | Final, "Hail Mary" super-ovulation + TI cycle before FET; BFP! EDD: 12/21/2022 | MMC 05/08/2022
05/20/2022 | D&C; recovering...
06/21/2022 | Trying naturally until October 2022
07/21/2022 | BFP! EDD 04/02/2023; 👦🏼 born on 4/5/2023
Oct '21 somewhat improved AMH (.51) and significantly improved FSH (8.9). Maybe it's all the pills I swallow.
Dec -21, standard antagonist. 225menupur/225gonal-f/cetrotide/5000u trigger, AFC 5; 11 days of stims. retrieval yields 5, 4M, 2 reach day-6 blast (4AB & 4BB). 1 low-level mosaic (chr. 3 deletion), 1 complex abnormal.
Feb '22 FET (low-level mosaic): CP.
May '22 egg retrieval, lupron flare protocol. HGH priming for 1 month before stims; md lupron 20/20u daily; menopur 225, follistim 225, 10k trigger after 8 days of stims; AFC 10; 13 retrieved; 10 mature; 8 fertilized. All frozen at 2PN for later thaw, grow, and biopsy.
July '22 egg retrieval same protocol: 9 days of stims; AFC 8; 10 retrieved, 8 mature, 4 fertilized and frozen.
Sept '22 ER same protocol: AFC 10; 12 retrieved, 11 mature, 11 fertilized.
From the 3 retrievals, 7 survived to day 5-6 blastocyst, from which I have 2 normal embryos!
Jan 20, Fully medicated FET, baby aspirin, dexamethasone, acupuncture, and as much woo as I can stand (which isn't very much). BFN.
July 23, Natural FET + baby aspirin. BFN.
TTC#2
TTC #2 ... preparing as of March 2024
TTC #1
TTC #1 02/2020 - 07/2022
2009 | Dx PCOS; likely a misdiagnosis
07/14/20 | Dx Hashimoto's Thyroditis
07/21/20 | 1st RE appointment
07/2120 - 08/20/20 | so much testing; no signs of PCOS
08/20/20 | Dx Unexplained; AMA
09/08/20 | IUI #1 Clomid + Trigger + Prometrium | BFN
09/30/20 | Urology consult; more testing required
10/2020 | Clomid + OPK + TI + Prometrium | BFN
10/26/2020 | Starting 2nd IUI cycle, with Letrazole and with a new RE / different clinic
11/03/2020 | New Dx "poor egg quality"; IUI cancelled in favor of Trigger + TI + Prometrium | BFN
11/26/2020 | Combo IUI (Clomid + Menopur) + Trigger + Prometrium | BFN
12/20/2020 | Combo IUI (Clomid + Gonal-F) + Trigger | IUI Cancelled due to thin lining; TI only | BFN
01/14/2021 | Combo IUI (Letrazole + Menopur) + Trigger | BFN
02/06/2021 | Switched to a new RE (TEW) ; trying naturally until we complete additional testing
03/14/2021 | Hybrid Double IUI, with Zymot (Letrazole, Gonal-F) + Trigger + Endometrin | Ovulated 4 mature eggs but still a BFN ☹️
04/07/2021 | Natural cycle while we regroup | BFN
04/09/2021 | Employer announces fertility benefits starting 05/01/2021! | Search for a new doctor who accepts insurance
05/10/2021 | New RE consult & plan for IVF
05/13/2021 | Mid-luteal IVF cycle #1 interrupted; had to get cancer genetic screening done to make sure I didn't have the same SDHA gene mutation as MH.
06/10/2021 | Aygestin priming IVF cycle #1; opted to Cx after 9 days of stims since only 5-6/12 follicles responded
07/26/2021 | Attempt #2 at IVF cycle #1 (mid-luteal start): 8 retrieved, 8 MII, 6 fert (1 PN3), 3 Day 5 & 6 blasts: 3AA, 3AA, 6AB; 3 euploid
08/09/2021 | Rest cycle / unmedicated TTC | Shockingly, a BFP! EDD: 5/25/202 | CP at 4w4d
09/23/2021 | IVF cycle #2 (mid-luteal start): 14 retrieved, 13 MII, 11 fert, 5 Day 5 & 6 blasts: 2 x 3AA, 2 x 3AB, 3BB; 2 euploid
11/12/2021 | IVF cycle #3 (mid-luteal start): cancelled due to ovaries being on vacation
12/20/2021 | Rest cycle / unmedicated TTC + Pregmune Immunology Testing; BFN
01/22/2022 | Rest cycle / unmedicated TTC + understanding uncovered immunological issues; BFN
02/18/2022 | Mock transfer cycle! ERA, ReceptivaDx, EMMA/ALICE; start Prednisone to address NK activity
03/16/2022 | Final, "Hail Mary" super-ovulation + TI cycle before FET; BFP! EDD: 12/21/2022 | MMC 05/08/2022
05/20/2022 | D&C; recovering...
06/21/2022 | Trying naturally until October 2022
07/21/2022 | BFP! EDD 04/02/2023; 👦🏼 born on 4/5/2023
Married 07/2012
DD born 07/2014
DD2 born 10/2018
DS born 10/2022
IF history:
TTC #2 since January 2016
June-Aug 2017: 3 IUIs w/Clomid = BFN
Sept 2017: Dx w/Endometriosis
Oct 2017: IUI w/Letrozole = BFN
Nov 2017: IUI w/Letrozole = BFN
Dec 2017: pre-IVF testing
Jan-Feb 2018: IVF--17 eggs retrieved, 13 fertilized, 9 frozen and 1 transferred on 2/10 = BFP on 2/19!!! EDD 10/29/2018
FET Oct 2021: BFP on 10/31! MC at 5 weeks
FET Feb 2022: BFP on 2/15! EDD 10/29/22
Oct '21 somewhat improved AMH (.51) and significantly improved FSH (8.9). Maybe it's all the pills I swallow.
Dec -21, standard antagonist. 225menupur/225gonal-f/cetrotide/5000u trigger, AFC 5; 11 days of stims. retrieval yields 5, 4M, 2 reach day-6 blast (4AB & 4BB). 1 low-level mosaic (chr. 3 deletion), 1 complex abnormal.
Feb '22 FET (low-level mosaic): CP.
May '22 egg retrieval, lupron flare protocol. HGH priming for 1 month before stims; md lupron 20/20u daily; menopur 225, follistim 225, 10k trigger after 8 days of stims; AFC 10; 13 retrieved; 10 mature; 8 fertilized. All frozen at 2PN for later thaw, grow, and biopsy.
July '22 egg retrieval same protocol: 9 days of stims; AFC 8; 10 retrieved, 8 mature, 4 fertilized and frozen.
Sept '22 ER same protocol: AFC 10; 12 retrieved, 11 mature, 11 fertilized.
From the 3 retrievals, 7 survived to day 5-6 blastocyst, from which I have 2 normal embryos!
Jan 20, Fully medicated FET, baby aspirin, dexamethasone, acupuncture, and as much woo as I can stand (which isn't very much). BFN.
July 23, Natural FET + baby aspirin. BFN.