Trying to Get Pregnant

IF Testing and Treatment w/o 10.25

Wife and I got tested for infertility recently  Infertility humor  Infertility Infertility awareness

This is a place for those of us who have already started TTC, but have started infertility testing and/or treatments. You can express your thoughts, feelings, and frustrations on infertility. TTC can be a long journey naturally, then add in the difficulties associated with infertility, and it becomes a whole new ball game. The road to infertility can be lonely, frustrating, and complicated, so let's make this a place where we can vent, ask questions, and support one another. Feel free to resurrect this thread at any point in the week if you have something to say. Treat this as an ongoing conversation.

Diagnosis (if you've been):  

Status (WTO/TWW/TTA):  

What are you doing this cycle? (Testing? Treatment?):  

How are things going?:  

Any questions?:  

GTKY: What's your favorite topping for a caramel apple? If you're not a fan of caramel apples, then what is your favorite fall treat?
*TW* History:
Me: 34 DH: 36 | Together since 2007 | Married July 2016

TTC #1 since 7.2017
Dx: low morph (1%), ANA positive, low decidualization score, high TSH and testosterone, histone antibodies

IUI #1-3 all BFN
IVF #1 | 6.11.19 | 24R, 17M, 15F, 6B, PGT-A tested - 5 normal, 3 girls & 2 boys
FET #1 | 9.10.19 | BFN "I know you, but we've never met. I'm with you, but I don't know your name"
RPL, Receptiva, & ERA testing | all normal/negative, recommended going on gluten and dairy free diet for next FET
FET #2 | 3.31.20 | Opted to cancelled due to pandemic, continued diet and tried naturally over the summer
2nd Opinion with another RE | 8.20.20 | Not immune to measles (received 1 dose); SA results similar to 2 years ago; decided to move forward with FET #2 redo at start of next cycle
Surprise natural BFP! | 9.22.20 | MC 10.23.20 at 8 weeks
TTCAL naturally | starting 11.22.20

Initial consultation with Reproductive Immunologist | 9.14.21
Decidualization score biopsy | 10.1.21 | abnormal - low score of 1; endometrial scratch recommended and progesterone supplementation
Saline sono | 10.15.21 | normal
Bloodwork | 10.21.21 high TSH, high testosterone, positive for anti-nuclear antibodies and histone antibodies, high protein S, multiple genetic mutations
BFP! | 11.3.21 | EDD 7.14.22 B) | biopsy provided same effect as endometrial scratch; added supplemental progesterone and estrogen, prednisone, levothyroxine, and MTX Support to maintain pregnancy
DS born 7.19.22 after induction


TTC #2 begins 6.2023
Consultation with RI | 6.6.23
Saline sono, endometritis biopsy, skin & eye check | all normal
Labs | high TSH, Factor XIII mutation, high %CD56
Follow up | 8.8.23 | prescribed metformin, prednisone, plaquenil, and levothyroxine
Repeat labs after 3 weeks on meds
Follow up | 11.9.23 | Green light!, increase in prednisone, added lovenox
Repeat labs in 8 weeks
Follow up | 1.16.24 | Green light continues
TTC put on pause
«13

Re: IF Testing and Treatment w/o 10.25

  • @kiki75 from last week just wanted to say what amazing ER results you got! Hope you’re getting some much deserved rest! Fx!

    Diagnosis (if you've been):  Unexplained secondary IF, Unexplained RPL, PCOS 

    Status (WTO/TWW/TTA):  testing phase

    What are you doing this cycle? (Testing? Treatment?):  bloodwork and SHG

    How are things going?:  Pretty good. I’m at my clinic now giving away all my blood to check my levels. Lol. But seriously they took a million viles today. Should have results later today and SHG scheduled for Friday!

    Any questions?:  

    GTKY: What's your favorite topping for a caramel apple? If you're not a fan of caramel apples, then what is your favorite fall treat?

    I love apples and love caramel but do not like biting into the caramel apple. Favorite fall treat would be apple cider donuts straight from the farm. 

    TTC#1 - March 2013

    BFP 8/9/13 - EDD 4/14/14 - DS born 4/23/14

    TTC#2 November 2015

    Dx: Secondary IF June 2016

    Medicated IUI cycle#1- Clomid+IUI -1/15/17 -BFN

    Break Mid 2017 - Resumed TTC December 2018

    "She believed she could so she did..."

    Medicated IUI cycle#2- Femara 5mg+IUI 12/22/18 - BFP 1/4/19 - MMC 2/1/19

    Saline Sono 3/15/19 - All Clear!

    Medicated IUI cycle#3- Femara 7.5mg+IUI 3/28/19-BFN

    Medicated IUI cycle#4- Femara 5mg+Gonal F 50iu+IUI 4/27/19- BFP 5/11/19 - MMC 6/12/19 - D&C 6/14/19-

    Incomplete M/C Repeat D&C - 7/3/19 -Testing concluded baby was genetically normal  :'(

    Dx: Unexplained RPL July 2019 - Tested + as carrier for Usher Syndrome & Familial Mediterranean Fever 

    Saline Sono 8/7/19 - Mostly Clear! All systems go for IVF#1 

    But will need a repeat Saline Sono between ER and FET

    IVF #1 - Antagonist Protocol - 8/17/19

    ER#1 8/27/19 - 12R, 6F, 4 biopsied+frozen! (3d5blasts + 1d6blast)- 2 PGS normal embabies!

    Saline Sono 9/13/19 - All Clear! Onto FET Prep#1

    FET#1 - 4AA -10/4/19 - BFP 10/14/19 - EDD - 6/21/20 -Beta#1-10dp5dt- 379 Beta#2-12dp5dt- 1007 Beta#3-14dp5dt- 2844

    DD born 6/15/20  <3

  • Loading the player...
  • @hanshotfirst77 I hope all your bloodwork comes back quickly! Good luck with the SHG!

    @kiki047 I'm so glad the ER went well and you're feeling better!!!

    Diagnosis (if you've been):  Endometriosis

    Status (WTO/TWW/TTA):  TWW

    What are you doing this cycle? (Testing? Treatment?):  FET

    How are things going?:  Just impatiently waiting and trying to take it easy. My work schedule got switched this week so I ended up with five days in a row off after the transfer which is nice. I switch to nights this week though, which is not so nice, especially since I'm trying to avoid coffee just in case.

    Any questions?:  Nope

    GTKY: What's your favorite topping for a caramel apple? If you're not a fan of caramel apples, then what is your favorite fall treat? I'm not a big caramel apple person. My favorite would have to be pumpkin pie!
    TTC History
    Me: 35 DH: 34
    Married 07/2012
    DD born 07/2014
    DD2 born 10/2018
    DS born 10/2022

    IF history:
    TTC #2 since January 2016
    June-Aug 2017: 3 IUIs w/Clomid = BFN
    Sept 2017: Dx w/Endometriosis
    Oct 2017: IUI w/Letrozole = BFN
    Nov 2017: IUI w/Letrozole = BFN
    Dec 2017: pre-IVF testing
    Jan-Feb 2018: IVF--17 eggs retrieved, 13 fertilized, 9 frozen and 1 transferred on 2/10 = BFP on 2/19!!! EDD 10/29/2018
    FET Oct 2021: BFP on 10/31! MC at 5 weeks
    FET Feb 2022: BFP on 2/15! EDD 10/29/22


  • @kiki047 As a DOR/AMA-ish lady myself, I am *thrilled* for your results. My feeling is-- we are all here for (at least) one reason, and I am hoping that @optimistgardener, @acleverusername and I all fall into the crappy eggs/great uterus camp. Lord knows you have had trouble on the uterus side, so the least the universe could give you is a great crop of embryos!! My heart hurt thinking how much it might take for you to get your 10 normals, and how unfair it was that you were in the tiny percentage for whom euploid embryos were not always enough, and so you needed *extra* stocking up. So I am *SO GLAD* you might not be in perpetual ER-hell. 
    TTC History
    TTC #1 Sep 2017-Sep 2018 
    BFP 11/30/2017 | MMC 12/31/2017
    BFP 6/22/2018 | CP 6/27/2018
    BFP 10/5/2018 | EDD 6/14/2019
    Baby girl born 6/19/19

    TTC #2 May 2020-November 2021
    BFP 7/18/2020 | MonoDi Twins | MMC 9/10/2020
    BFP 11/7/2020 | CP 11/9/2020
    RE Consult January 2021 | Dx "borderline DOR"/RPL
    IVF with PGT:
    Standard Antagonist:
    ER #1 3/27/2021 7R | 5M | 3F | 2B | 1 PGT-A Normal, 1 low-level mosaic
    ER #2 4/22/2021 10R | 7M | 3F | 2B | 0 normal, 2 aneuploid
    ER #3 5/19/2021 2R | 1M | 0F
    Estrogen Priming Antagonist:
    ER #4 7/10/2021 5R | 4M | 3F | 1B | 1 PGT-A Normal
    Duostim  (Standard Antagonist):
    ER #5 9/22/2021 13R | 11M | 8F | 5B | 2 PGT-A Normal, 1 low-level mosaic, 2 aneuploid
    ER #6 10/9/2021  9R | 6M | 4 F | 1B | 1 aneuploid
    FET #1  11/5/2021 | EDD 7/24/2022
    Baby boy born 7/19/22

    TTC #3 since May 2023 (ntnp)
    IVF Started Fall 2023 (Standard Antagonist)
    ER #7 10/6/2023 | 9R | 6M | 5F | 3B | 2 aneuploid, 1 high-level mosaic
    ER #8 10/31/2023 | 5R | 4M | 3F | 1B | 1 PGT-A Normal
    FET #2 11/27/23 | CP (bHCG = 8)
    FET #3 planned Jan 2024



  • @kiki047 I'm sorry... WHAT?!?! I have never heard of this!!! Is every update going to have a plot twist? Oh my god.
    Oh My God David GIF - Oh My God David Dan Levy - Discover amp Share GIFs

    *TW* History:
    Me: 34 DH: 36 | Together since 2007 | Married July 2016

    TTC #1 since 7.2017
    Dx: low morph (1%), ANA positive, low decidualization score, high TSH and testosterone, histone antibodies

    IUI #1-3 all BFN
    IVF #1 | 6.11.19 | 24R, 17M, 15F, 6B, PGT-A tested - 5 normal, 3 girls & 2 boys
    FET #1 | 9.10.19 | BFN "I know you, but we've never met. I'm with you, but I don't know your name"
    RPL, Receptiva, & ERA testing | all normal/negative, recommended going on gluten and dairy free diet for next FET
    FET #2 | 3.31.20 | Opted to cancelled due to pandemic, continued diet and tried naturally over the summer
    2nd Opinion with another RE | 8.20.20 | Not immune to measles (received 1 dose); SA results similar to 2 years ago; decided to move forward with FET #2 redo at start of next cycle
    Surprise natural BFP! | 9.22.20 | MC 10.23.20 at 8 weeks
    TTCAL naturally | starting 11.22.20

    Initial consultation with Reproductive Immunologist | 9.14.21
    Decidualization score biopsy | 10.1.21 | abnormal - low score of 1; endometrial scratch recommended and progesterone supplementation
    Saline sono | 10.15.21 | normal
    Bloodwork | 10.21.21 high TSH, high testosterone, positive for anti-nuclear antibodies and histone antibodies, high protein S, multiple genetic mutations
    BFP! | 11.3.21 | EDD 7.14.22 B) | biopsy provided same effect as endometrial scratch; added supplemental progesterone and estrogen, prednisone, levothyroxine, and MTX Support to maintain pregnancy
    DS born 7.19.22 after induction


    TTC #2 begins 6.2023
    Consultation with RI | 6.6.23
    Saline sono, endometritis biopsy, skin & eye check | all normal
    Labs | high TSH, Factor XIII mutation, high %CD56
    Follow up | 8.8.23 | prescribed metformin, prednisone, plaquenil, and levothyroxine
    Repeat labs after 3 weeks on meds
    Follow up | 11.9.23 | Green light!, increase in prednisone, added lovenox
    Repeat labs in 8 weeks
    Follow up | 1.16.24 | Green light continues
    TTC put on pause
  • @kiki75 omg that is an awesome update! I understand how that is a tough call though cause you won’t know how many make it past PGT a but I think your plan to just move forward is a good one. It’s so hard when the numbers drop off but you have such positive results so far such good numbers to start with. I got everything crossed for you. 

    @bumblebee0210 so exciting you’re gearing up for FET! I’ll be thinking thick for you!

    @shortstack930 are you waiting til beta to test?

    @inthewoods23 lol it was a lot. Like I want to say about 15. I just looked at them and was like wow that’s a lot of blood. And she was like I promise we left you some lol 😂 

    TW I’m glad you got such good response to your loss anniversary that can be tough but sometimes it really does help to be able to talk about it. 

    AFM Also TW and will spoiler this part


    I felt really weird and kinda got some traumatic flashbacks when they did an ultrasound I wasn’t expecting today. It was just to check my ovaries which looked fine, very PCOS-y as usual. But idk I didn’t expect to feel so triggered. 


    TTC#1 - March 2013

    BFP 8/9/13 - EDD 4/14/14 - DS born 4/23/14

    TTC#2 November 2015

    Dx: Secondary IF June 2016

    Medicated IUI cycle#1- Clomid+IUI -1/15/17 -BFN

    Break Mid 2017 - Resumed TTC December 2018

    "She believed she could so she did..."

    Medicated IUI cycle#2- Femara 5mg+IUI 12/22/18 - BFP 1/4/19 - MMC 2/1/19

    Saline Sono 3/15/19 - All Clear!

    Medicated IUI cycle#3- Femara 7.5mg+IUI 3/28/19-BFN

    Medicated IUI cycle#4- Femara 5mg+Gonal F 50iu+IUI 4/27/19- BFP 5/11/19 - MMC 6/12/19 - D&C 6/14/19-

    Incomplete M/C Repeat D&C - 7/3/19 -Testing concluded baby was genetically normal  :'(

    Dx: Unexplained RPL July 2019 - Tested + as carrier for Usher Syndrome & Familial Mediterranean Fever 

    Saline Sono 8/7/19 - Mostly Clear! All systems go for IVF#1 

    But will need a repeat Saline Sono between ER and FET

    IVF #1 - Antagonist Protocol - 8/17/19

    ER#1 8/27/19 - 12R, 6F, 4 biopsied+frozen! (3d5blasts + 1d6blast)- 2 PGS normal embabies!

    Saline Sono 9/13/19 - All Clear! Onto FET Prep#1

    FET#1 - 4AA -10/4/19 - BFP 10/14/19 - EDD - 6/21/20 -Beta#1-10dp5dt- 379 Beta#2-12dp5dt- 1007 Beta#3-14dp5dt- 2844

    DD born 6/15/20  <3

  • @kiki047 that is an amazing update!!!! I'm so happy for you!! We did never PGT tested our embryos so I would think you'd be fine to go right into a transfer next cycle without the results yet, depending on your history (which I can't see because the signatures have all disappeared randomly!) Typically at work on nights it's slightly less busy so I'm hoping that will be a plus for me.

    @inthewoods23 I picked up some half caff coffee to see if that helps but I might switch to decaf eventually. Yikes about the blood draw! I've had that happen to me before and it's awful.

    @hanshotfirst77 I'm debating on if I want to test the day before (Halloween) since DH and I will both be home to see the results together. I'm sorry you got triggered by the u/s. When I first went back to the RE this time I had a wave of flashbacks right away that immediately gave me anxiety, which I totally did not expect. I hope you're able to do something for yourself today to take your mind off of things.
    TTC History
    Me: 35 DH: 34
    Married 07/2012
    DD born 07/2014
    DD2 born 10/2018
    DS born 10/2022

    IF history:
    TTC #2 since January 2016
    June-Aug 2017: 3 IUIs w/Clomid = BFN
    Sept 2017: Dx w/Endometriosis
    Oct 2017: IUI w/Letrozole = BFN
    Nov 2017: IUI w/Letrozole = BFN
    Dec 2017: pre-IVF testing
    Jan-Feb 2018: IVF--17 eggs retrieved, 13 fertilized, 9 frozen and 1 transferred on 2/10 = BFP on 2/19!!! EDD 10/29/2018
    FET Oct 2021: BFP on 10/31! MC at 5 weeks
    FET Feb 2022: BFP on 2/15! EDD 10/29/22


  • @kiki047 what an amazing plot twist! 
    @hanshotfirst77 I hope they left you some blood! Sometimes getting 2 vials from me is a struggle, not looking forward to next months tests 
    @bumblebee0210 thinking thick for you! 
    @shortstack930 Glad you got some time off after your transfer! Maybe a switch up in schedule will help the time pass. 
    @inthewoods23 I hate when they dig the needle around. My clinic has bruised me at every.single.draw. it's the worst.

    Diagnosis (if you've been):  AMA, DOR, low morph

    Status (WTO/TWW/TTA):  TWW

    What are you doing this cycle? (Testing? Treatment?):  waiting for this cycle to end, then start BCP for ER prep!

    How are things going?:  I did not feel well last week, kind of ghosted TB (and life in general) but glad to be back active this week even if nothing interesting is happening with me.

    Any questions?:  *I will also ask my RE when I see him* but what are your thoughts on going to a theme park within the week after ER? Long story short its a birthday vacation for DHs family and it is a VERY big deal if we decline but it happens to land at the end of the week my clinic does ER. I obviously have no idea which day my ER will land during that week so it could be anywhere from 1-6 days after. 

    GTKY: What's your favorite topping for a caramel apple? If you're not a fan of caramel apples, then what is your favorite fall treat? There is a festival here that slices the apples before dipping in caramel and I love that so much more than a whole messy apple. Especially if there is some sort of chocolate added! 
  • Sorry I’ve been so absent here lately! Coming back with an actual update today! But first, tags.

    @hanshotfirst77 FX for good and speedy results! And totally agreed about cider donuts! Yummm!

    @kiki047 that’s so amazing about your ER!! And those numbers are awesome! I’m so excited for you!

    @bumblebee0210 sending you all the good vibes for your transfer next week!! Hopefully you’re able to relax and de-stress and take the pressure off yourself (which I know is way easier said than done). 

    @shortstack930 that’s awesome that your schedule works out so nicely after your transfer! 

    @inthewoods23 I’m glad you were able to open about your loss and got good responses. I’m definitely someone that finds it freeing to talk openly about my IF and losses. 

    @walkawaynee no advice about the amusement park. That sounds really fun though! Hopefully you’re able to go. 

  • @bumblebee0210 thank you for the reassurance. You're right, we're all faced with our own set of challenges, and *making* embryos has never been our problem. Thankfully they do the testing in-house so no need to ship those samples anywhere this time. I am hopeful that this RE will be able to figure out our RIF/RPL issues, and we finally have a real shot at moving on from TTC/IF hell. And even more hopeful that you're one of the lucky ones that will have great success with euploid embryos too. FX!
    @inthewoods23 I'm still totally shocked too. I kind of hope that our Day 5 update is perfectly drama-free and will be channeling all of my "good vibes only" juju from here on out. 
    @hanshotfirst77 that's where I'm at too, like talk about putting all your eggs in one basket lol. There's no way. I'm expecting my next cycle to start anywhere from 7-10 days post-ER so sometime this weekend or next week. At least by that time I'll know how many we have to test. 
    @shortstack930 thank you!! We're planning on doing back to back embryo banking with the hopes of having around 12 euploid embryos before we start transferring any.  Since all of our siggies are missing, *TW* we've now done 3 transfers of euploid embryos resulting in 1 implantation failure and 2 miscarriages at 11w and 5w2d, and 1 failed fresh transfer of a non-tested embryo. The rest of our embryos from that second ER were either abnormal or mosaic, which is why we're banking more now before we even think about any more FETs. We only got 3 blasts from the first round (all euploid), and 6 from the second (2 untested, 3 abnormal, 1 low level mosaic). 
    @walkawaynee ooh that's a tough one about theme parks. I know for me, I had my ER on Friday and was completely out of commission for the next 24hours, and still pretty sore and uncomfortable on the Sunday. I'm only just starting to feel less tender and bloated today, but I noticed my spotting is back so I'm still actively bleeding which says to me that I'm still not healed internally from them digging around in there for eggs. If it was closer to the end of the week, like 5-7 days later I don't think it would be a problem but then of course there's any risk of OHSS which you won't know how that'll affect you until it happens. Then again, some people feel perfectly fine after.

    TTC History:

    Me: 36  MH: 39, TTC since Dec 2017

    Aug '18: PCOS dx

    Nov '18: MH SA - 19mil

    Dec '18-Mar '19: Letrozole + TI - all BFN

    Apr '19: Letrozole + TI, - BFN.  Repeat SA (27mil) & DNA fragmentation test (17%)

    Aug '19: Letrozole + HCG trigger + IUI + prog supp - BFN (MH: 16mil)

    Sep '19: 2nd IUI, same protocol - BFN (MH: 16mil) 

    Dec '19: IVF #1 w/ICSI, PGT. 5 retrieved, 4 fertilized, 3 blasts, 3 PGT-A normal.

    Mar '20: FET #1, perfect 5AA blast transferred. BFN.

    Sept '20: FET #2, 5BB tsf. 9/18/20 BFP!! EDD: 5/27/21. MMC 11w                                                  

    Feb ‘21: FET #3, last 6BB blast transferred. BFP, EDD 11/2/21. MC 5w3d. 

    May '21: IVF #2 w/ICSI, PGT. 8R, 7M, 6F, 6 blasts - 3AB, 3AB, 3BB, 4BB, 5BB, 6BA. Fresh tsf 5/13/21 - BFN. 

    June '21: PGT-A results = 3 abnormal, 1 low level mosaic. Referred to new REI, had consult with 2nd RE in between. 


    Sept '21: RPL, immune testing normal

    Oct '21: IVF #3 w/IMSI, PGT. 33R, 26M, 23F, 9 blasts (7 day 6, 2 day 7). PGT-A = 5 normal, 1 mosaic

    Dec '21: Positive for endometritis, RX Flagyl & Keflex

    Jan '22: FET #5 - Kitchen sink immune/RIF protocol incl. PRP, intralipids, prednisone, medrol, nivestym, fragmin - CP

    Feb '22: FET #6 - Kitchen sink immune/RIF protocol w/higher doses of pred & fragmin - BFN

    Mar '22: Mock cycle for ERA - cancelled, repeat endometrial biopsy instead. Still positive for endometritis. RX ciprofloxacin & amoxicillin. 

    Apr '22: IVF #4 w/IMSI, PGT. 28R, 23M, 16F, 11 blasts. PGT-A = 6 normal. 

    June '22: FET #7 - Microdose lupron downreg w/kitchen sink immune/RIF protocol - double embryo transfer. BFN.

    July '22: FET #8 - Mini stim w/Puregon + trigger, kitchen sink immune/RIF protocol. BFN. 

    Sep '22: Taking a break

    Dec '22: Attempted abdominal myomectomy, fibroid too close to cervix and major blood vessels. Wasn't removed. 

    Feb '23: FET #9 - Modified natural w/baby asp, HCG trigger, PIO, PRP, Medrol, HCG wash, embryo glue - BFP!! EDD 11/11/23


  • Diagnosis (if you've been):  PCOS

    Status (WTO/TWW/TTA):  WTO 

    What are you doing this cycle? (Testing? Treatment?):  testing 

    How are things going? Things are great. My consult with my RE was today with I felt like it went really well. I am so grateful for this group and all the knowledge I have gained from being here because I felt like I really understood everything we discussed in my consult and she was impressed with a lot of the questions I was asking. The plan is to do 3-4 more medicated cycles with Letrozole but my RE is adding metformin and Myo-inositol for me and we’ll do lining and follicle monitoring. The nurse called shortly after the appointment and I’m thrilled that they’re letting me do my blood work and baseline US locally. I have that scheduled for next week and then I’ll start Letrozole, despite it being CD 40 right now. Looks like the next step from today is to start metformin.

    The plan if the medicated cycles aren’t successful is to look at IUI.

    Any questions?: natm 

    GTKY: What's your favorite topping for a caramel apple? If you're not a fan of caramel apples, then what is your favorite fall treat? 

    I like caramel and apples dipped in it, but I don’t like the caramel apples on a stick. Cider donuts are definitely a weakness for me.  

  • @hanshotfirst77 thanks for leaving some haha

    @walkawaynee IMO, as long as you're feeling well and not in pain you're probably good to go on the trip. Maybe don't ride the really intense rides if you're not 100%. From my experience - I recovered super fast after my ER. Like my dad had no idea when we had greasy burgers at Red Robin for dinner that night that I had just had major surgery 6 hours prior.
    *TW* History:
    Me: 34 DH: 36 | Together since 2007 | Married July 2016

    TTC #1 since 7.2017
    Dx: low morph (1%), ANA positive, low decidualization score, high TSH and testosterone, histone antibodies

    IUI #1-3 all BFN
    IVF #1 | 6.11.19 | 24R, 17M, 15F, 6B, PGT-A tested - 5 normal, 3 girls & 2 boys
    FET #1 | 9.10.19 | BFN "I know you, but we've never met. I'm with you, but I don't know your name"
    RPL, Receptiva, & ERA testing | all normal/negative, recommended going on gluten and dairy free diet for next FET
    FET #2 | 3.31.20 | Opted to cancelled due to pandemic, continued diet and tried naturally over the summer
    2nd Opinion with another RE | 8.20.20 | Not immune to measles (received 1 dose); SA results similar to 2 years ago; decided to move forward with FET #2 redo at start of next cycle
    Surprise natural BFP! | 9.22.20 | MC 10.23.20 at 8 weeks
    TTCAL naturally | starting 11.22.20

    Initial consultation with Reproductive Immunologist | 9.14.21
    Decidualization score biopsy | 10.1.21 | abnormal - low score of 1; endometrial scratch recommended and progesterone supplementation
    Saline sono | 10.15.21 | normal
    Bloodwork | 10.21.21 high TSH, high testosterone, positive for anti-nuclear antibodies and histone antibodies, high protein S, multiple genetic mutations
    BFP! | 11.3.21 | EDD 7.14.22 B) | biopsy provided same effect as endometrial scratch; added supplemental progesterone and estrogen, prednisone, levothyroxine, and MTX Support to maintain pregnancy
    DS born 7.19.22 after induction


    TTC #2 begins 6.2023
    Consultation with RI | 6.6.23
    Saline sono, endometritis biopsy, skin & eye check | all normal
    Labs | high TSH, Factor XIII mutation, high %CD56
    Follow up | 8.8.23 | prescribed metformin, prednisone, plaquenil, and levothyroxine
    Repeat labs after 3 weeks on meds
    Follow up | 11.9.23 | Green light!, increase in prednisone, added lovenox
    Repeat labs in 8 weeks
    Follow up | 1.16.24 | Green light continues
    TTC put on pause
  • @hanshotfirst77 its crazy how much blood they have to take sometimes! haha. hope the results look good. sorry about the triggering US, thats not fun at all. i hate when things like the sneak up on you.

    @kiki75 yay for a success last week!!! i hope the bloating is getting better! that baymax gif is perfect haha. glad to hear you still have 23 great ones!!!!! also, i am not seeing siggys as well.

    @bumblebee0210 exciting for a tentative transfer soon! the anxiety totally makes sense. hang in there!

    @shortstack930 thats nice that you have five days off after the transfer!! relax and rest up! but nights....yucky. hopefully you can get by with little caffeine needed!

    @inthewoods23 ugh i hate when they dig in your arm and miss the vein!! im super pale too, so i get the biggest bruises. glad to hear you got support from your fb post though, that is great. and sorry your chart is being garbage!

    @walkawaynee im not sure about the amusement park, but i do love me a trip to a theme park! haha. what i would give to be at disneyland right now....

    @gingermama29 im glad your meeting with your RE went well and you like the plan you have! it sounds similar to ours - medicated timed intercourse for now. is this your first time taking metformin? if so, just be prepared for some stomach problems, haha.....maybe tmi, but it majorly affects my digestive tract. i have to slowly increase my doses or i just run to the bathroom all day lol



    Diagnosis (if you've been):  PCOS

    Status (WTO/TWW/TTA):  WTO

    What are you doing this cycle? (Testing? Treatment?):  timed intercourse with meds

    How are things going?:  pretty good! i had a follicle monitoring US on Friday and it was just at 12mm, so they checked again this morning and its at 19mm. so we trigger tomorrow night, BD Wednesday and Thursday, and then wait for a blood test on 11/9! and i can finally stop the dexamethasone this cycle....that stuff is just brutal. hopefully ill sleep better now and not be constantly sweating haha. 

    Any questions?:  none right now

    GTKY: What's your favorite topping for a caramel apple? If you're not a fan of caramel apples, then what is your favorite fall treat? i like caramel apples with like chocolate & toffee bits or snickers pieces! but like everyone else has said, apple cider donuts are sooooo good. there is a farm here that we have a season pass to and they have the best fresh cider donuts every day. they close for the season this saturday, so we will probably have to go stock up on a few dozen haha

    married to DH on March 15, 2018 <3 TTC since May 2018
    dx: PCOS, hypothroidism <3 tx: timed intercourse with meds (dexa, clomid, letrozole, metformin, trigger shots)
    First TTGP: 5/9/19 BFN, 6/21/19 BFN, 7/29/19 BFN, 8/1/19 started a break from tx, 11/16/19 surprised with a BFP! LO born 7/7/20
    Second TTGP: started meds for first cycle of tx on 10/13/21


  • @gingermama29 yay I'm so glad your consult went well, and that you impressed your RE ;)  As a fellow PCOS "Cyster", I hope the combo of metformin and myo-inositol helps. I noticed a huge difference when I started taking them 3 years ago, and I'm still on both to this day. Like @knockupthestock the Metformin also gives me major gastro issues, always has, so ease into it slowly. I'm told that if you're low carb it affects you less but that was not the case for me during keto so I think that's a load of BS lol. My RE makes some kind of metformin cream that I use topically that is supposed to be a more bioavailable form but I think that's a proprietary product because it doesn't even have a DIN, so if you find it gives you stomach upset I think there's also a timed release 1500mg pill that you can take at night that is supposed to be more gentle. Good luck! 
    @knockupthestock I've had many Baymax moments but this was one of the worst, lol. *TMI* add on the fact that I didn't poop for over 48hrs and I was all sorts of uncomfortable. Yay for triggering soon! 

    @bumblebee0210@acleverusername@optimistgardener I am paging our resident experts here with this question. I've already emailed the nurse but maybe you can make some more sense of my thought process... so I had some spotting post-ER on Friday and Saturday, which had basically tapered off by Saturday night and was completely gone by Sunday. Have had some mild to moderate cramping, which is manageable with Tylenol as instructed in my discharge papers. But today I have had some discharge, bright red bleeding and cramping that is more in line with what I would expect with a full period. Except that I'm only 3 days post-ER. I was not expecting AF until 7-9 days after. However, I am also on 2.5mg of letrozole which studies have shown to be good to ward off OHSS because of its ability to lower serum E2 levels. So is it reasonable to assume that this is basically a withdrawal bleed from a crash in my hormone levels? *Important to note that I've had spotting through two of my FET prep cycles where my estradiol supplementation wasn't enough to sustain my lining and I've had to double my doses plus add a patch, so it's not unreasonable to think that a sudden crash in E2 levels could make my body think it needs to shed my lining, right? 
    My main reason of concern isn't because I think I'm bleeding out, but because we had discussed doing back to back banking cycles, so by that definition, would today have been considered my CD1? And if so, isn't it too soon? This question is more for the nurse, who I hope responds to me ASAP. 


    TTC History:

    Me: 36  MH: 39, TTC since Dec 2017

    Aug '18: PCOS dx

    Nov '18: MH SA - 19mil

    Dec '18-Mar '19: Letrozole + TI - all BFN

    Apr '19: Letrozole + TI, - BFN.  Repeat SA (27mil) & DNA fragmentation test (17%)

    Aug '19: Letrozole + HCG trigger + IUI + prog supp - BFN (MH: 16mil)

    Sep '19: 2nd IUI, same protocol - BFN (MH: 16mil) 

    Dec '19: IVF #1 w/ICSI, PGT. 5 retrieved, 4 fertilized, 3 blasts, 3 PGT-A normal.

    Mar '20: FET #1, perfect 5AA blast transferred. BFN.

    Sept '20: FET #2, 5BB tsf. 9/18/20 BFP!! EDD: 5/27/21. MMC 11w                                                  

    Feb ‘21: FET #3, last 6BB blast transferred. BFP, EDD 11/2/21. MC 5w3d. 

    May '21: IVF #2 w/ICSI, PGT. 8R, 7M, 6F, 6 blasts - 3AB, 3AB, 3BB, 4BB, 5BB, 6BA. Fresh tsf 5/13/21 - BFN. 

    June '21: PGT-A results = 3 abnormal, 1 low level mosaic. Referred to new REI, had consult with 2nd RE in between. 


    Sept '21: RPL, immune testing normal

    Oct '21: IVF #3 w/IMSI, PGT. 33R, 26M, 23F, 9 blasts (7 day 6, 2 day 7). PGT-A = 5 normal, 1 mosaic

    Dec '21: Positive for endometritis, RX Flagyl & Keflex

    Jan '22: FET #5 - Kitchen sink immune/RIF protocol incl. PRP, intralipids, prednisone, medrol, nivestym, fragmin - CP

    Feb '22: FET #6 - Kitchen sink immune/RIF protocol w/higher doses of pred & fragmin - BFN

    Mar '22: Mock cycle for ERA - cancelled, repeat endometrial biopsy instead. Still positive for endometritis. RX ciprofloxacin & amoxicillin. 

    Apr '22: IVF #4 w/IMSI, PGT. 28R, 23M, 16F, 11 blasts. PGT-A = 6 normal. 

    June '22: FET #7 - Microdose lupron downreg w/kitchen sink immune/RIF protocol - double embryo transfer. BFN.

    July '22: FET #8 - Mini stim w/Puregon + trigger, kitchen sink immune/RIF protocol. BFN. 

    Sep '22: Taking a break

    Dec '22: Attempted abdominal myomectomy, fibroid too close to cervix and major blood vessels. Wasn't removed. 

    Feb '23: FET #9 - Modified natural w/baby asp, HCG trigger, PIO, PRP, Medrol, HCG wash, embryo glue - BFP!! EDD 11/11/23


  • seriously, you guys. how's a person supposed to keep up when a board is this hoppin'? 
    As for everyone's comments about the missing signatures, I grouched about this over on the randoms thread. Some experimenting has led me to find that my signature miraculously reappears (at least for me!) when I put an extra line above the spoilered text in the signature box. The extra line has to include unspoilered text (hence my signature now is titled "History"). And voila, the signature thing works again. But seriously, what the heck TB website coding people, fix this please.
    @kiki047 so interesting that you've had problems with anesthetic in the past. seems like a really useful thing to know about yourself, so you can warn your future anesthesiologists! Also re: your update: dude. Just. Amazing, you are an egg-making rockstar.
    @bumblebee0210 my fingers are crossed so hard for a successful transfer for you. i can only imagine that anxiety after all the hard work you've put into getting those embryos.
    skip spoiler in case you're in good vibes only mode:
    i remember last week we were talking different FET protocols. have you had a discussion with the clinic about (heaven forbid) how they might adjust your prep if this transfer doesn't take? also, sorry, my brain is mush and i have the memory of a goldfish. sorry if you've discussed that recently.

    @shortstack930 you do you, but i'm on team "go ahead and drink a cup of coffee" in case you need permission for small doses of caffeine to get you through the night shift change. that sounds super rough! but i'm glad you got some time off after the transfer.
    @inthewoods23 big cheers on your public honesty about this process. I've not been SM honest, but I've definitely been like "oh, you asked me how i've been doing? well here's how I've been doing" honest with friends and family who have made the mistake of asking me how i've been doing, haha. it can be really freeing to put it out there.
    @walkawaynee others have already answered the theme park question but my sense is that the difference between 1 day after vs 6 days after is significant. My recovery was pretty minimal because an 8-egg retrieval is not, like, a 33-egg retrieval. more follicles will mean more just, physical damage done in the act of retrieval, plus your body will have to deal with first making space for all them eggs and then retreating back to normal dimensions again... but still, I would not have been very interested in doing any theme park rides for at least 3 or 4 days afterwards. I did not have spotting afterwards, and I was (at least kind of) able to get on a bicycle two days later and ride a couple of miles downtown (but i regretted it a little afterwards). I also managed to get in a car and drive four hours down the freeway a couple of days later. but if I felt basically competent for normal life stuff, I wasn't really up for crazy jostling or tumbly belly stuff. I had some nausea that crept up on me late the day of retrieval when the anti-nausea meds had worn off, and kind of lurked on me for a day or so.
    @gingermama29 yay!!! for things are great. so nice when people get to say that and feel that on this board. :)
    @knockupthestock congrats on getting to be done with the dex! do they do a dose reduction thing or do they cut you off all at once?

    Diagnosis (if you've been):  decrepit ovary, some endo, generally iffy abdominal scarring situation but the uterus looks good via hysteroscope, so there's that.

    Status (WTO/TWW/TTA): TWW, but just for giggles

    What are you doing this cycle? (Testing? Treatment?):  mostly I'm just waiting for my ER in late november/early december. I can't believe it's already creeping up on me.

    How are things going?:  I'm so glad to be distracted with a million things right now. I've got my drugs all delivered and my cycle is partially paid (just gotta call and pay the rest soonish), but things seem basically lined up. I'm torn between feeling cautiously optimistic and feeling just kinda fatalistic. As @bumblebee0210 keeps telling us, disparity in cycle outcomes is a thing, and i'm rolling the dice fresh this time, and also my relevant (potentially related to egg quality) bloodwork is all better than it was previously (my AMH, my FSH, and also for once in my life I am within what amounts to a rounding error for normal D levels). So those are all good things. But at the same time, part of my brain is just like, "dude, you have crappy eggs and you know it. you were lucky last time to get so many retrieved and then to blast stage. what if you can't even do that this time?"
    Any questions?: This is one of those "just ask the clinic" questions, but what the heck: The nurse coordinator sent me a list of the total quantities for all the drugs i'll be taking this cycle way back in September. She basically said I should do the math and then revise the prescription order she sends to the pharmacies based on what I already have in my possession and how much I need to "top up" to the required amount. In the interim since that email, it seems like the clinic increased the amount of Gonal-F that they want me to buy for this cycle, and the new list has an extra 450-unit Gonal-F pen in it. Anyway, I did the math, and the amounts that the first nurse asked me to order would readily cover my stimming at the high doses I did last time for 8 straight days. Last time around and also in the last two medicated IUI cycles I did, I only stimmed for 5.5 days before they had me trigger. So if they now want me to have an extra 450 units of Gonal-F, that would mean I would be good to go in case i had to stim for 10 days total, which honestly does not seem plausible, considering my track record. So I went ahead and ordered drugs based on the earlier list, but now I am wondering if I'm playing things too risky. Discuss?
    Another question, perhaps less esoteric: My clinic only has me trigger on 5000 units of Novarel, but I've heard chatter on this board (i believe from @acleverusername) that 10k units might be better. any reason i should ask to upgrade? as you know, my maturation rates last time around were decent.
    GTKY: What's your favorite topping for a caramel apple? If you're not a fan of caramel apples, then what is your favorite fall treat?
    I feel like @inthewoods23 was just hungry for caramel apples when she wrote this question. Honestly, I love the idea of a caramel apple, but the "in theory" aspect of the thing runs up against the reality that I hate and despise mushy apples, and it seems like caramel apples are always mushy. if it were a perfectly crisp apple, i'd love to do just a simple caramel-only dip (actually dipped slices sounds even better, because the apple to caramel ratio would be better, and the whole thing less messy). But if the apple is not perfectly crisp, well then I guess I'd probably be on team "apple cider donut" with the rest of y'all.

    History
    I am doing this on my own. Left ovary and fallopian tube removed due to cyst/necrosis just after birth. Right ovary and tube still purport to function.
    Began TTC in Aug '18 @ age 35
    5 or 6 (or 7?!) cycles using frozen donor sperm, ICI. All BFN
    Mar-Jun '19 IUIs, all BFN
    Began process of referral for RE in spring of '19, blood tests confirm low AMH (.54) but all else is good.
    May '19 HSG shows open tube, but ultrasound suggests fibroids
    MRI in June '19 confirms two large fibroids, one growing through wall of uterus
    In June '19 I move from California to Oregon, disrupting my insurance, referrals, etc. 5 months spent piecing it all back together.
    Nov. '19 attempted myomectomy (vaginal approach) failed. 2nd surgery using laparoscopic method in Jan '20 is successful.
    April '20 --> June '20, natural IUIs, all BFN.
    July? saline ultrasound and bubble test demonstrate open tube
    July '20 clomid cycle cancelled for thin lining
    Aug-Oct, 3 femara cycles, all BFN
    RE referral. While waiting to set up an appointment Nov-Jan,I continue with natural cycles and ICI, using a known donor, BFN...
    Jan '21 more bloodwork, AMH is worse (.30), FSH high albeit not catastrophic at 13.2. hysteroscopy all good. "looks cozy!" says the RE.
    Feb '21, injectables (menopur, novarel), iui, BFN (doc said the frozen donor sperm sample had the "best numbers she'd ever seen!")
    Mar '21, injectables, iui cancelled due to lack of follicles, converted to at home-insem. BFN
    May '21, first IVF round cancelled due to cyst.
    July '21 IVF: standard antagonist. 225menupur/225gonal-f/cetrotide/5000u trigger, AFC 7; 6 days of stims. 8 eggs retrieved, 7 mature, 5 fertilize, 4 made it to blast. 3 are 4AB, 1 is 4BB. PGT-A results all abnormal.
    Oct '21 somewhat improved AMH (.51) and significantly improved FSH (8.9). Maybe it's all the pills I swallow.
    Dec -21, standard antagonist. 225menupur/225gonal-f/cetrotide/5000u trigger, AFC 5; 11 days of stims. retrieval yields 5, 4M, 2 reach day-6 blast (4AB & 4BB). 1 low-level mosaic (chr. 3 deletion), 1 complex abnormal.
    Feb '22 FET (low-level mosaic): CP.
    May '22 egg retrieval, lupron flare protocol. HGH priming for 1 month before stims; md lupron 20/20u daily; menopur 225, follistim 225, 10k trigger after 8 days of stims; AFC 10; 13 retrieved; 10 mature; 8 fertilized. All frozen at 2PN for later thaw, grow, and biopsy.
    July '22 egg retrieval same protocol: 9 days of stims; AFC 8; 10 retrieved, 8 mature, 4 fertilized and frozen.
    Sept '22 ER same protocol: AFC 10; 12 retrieved, 11 mature, 11 fertilized.
    From the 3 retrievals, 7 survived to day 5-6 blastocyst, from which I have 2 normal embryos!
    Jan 20, Fully medicated FET, baby aspirin, dexamethasone, acupuncture, and as much woo as I can stand (which isn't very much). BFN.
    July 23, Natural FET + baby aspirin. BFN.
  • @kiki047 oh shoot! So sorry to hear you're maybe already at CD1 again. I honestly have no useful thoughts on this, but considering it's so soon after your retrieval and also because you are supposed to be doing BTB retrievals, you definitely need to get the clinic to reply to you on this ASAP. In the meantime, you know this but make sure you're using external methods only for dealing with the flow. And even if you haven't totally soaked through a pad, I'd say change your pads more regularly than you otherwise might, just to be really confident that things are squeaky clean because I am sure that your body is still in the process of healing and you don't want to introduce any unwanted bacteria.
    History
    I am doing this on my own. Left ovary and fallopian tube removed due to cyst/necrosis just after birth. Right ovary and tube still purport to function.
    Began TTC in Aug '18 @ age 35
    5 or 6 (or 7?!) cycles using frozen donor sperm, ICI. All BFN
    Mar-Jun '19 IUIs, all BFN
    Began process of referral for RE in spring of '19, blood tests confirm low AMH (.54) but all else is good.
    May '19 HSG shows open tube, but ultrasound suggests fibroids
    MRI in June '19 confirms two large fibroids, one growing through wall of uterus
    In June '19 I move from California to Oregon, disrupting my insurance, referrals, etc. 5 months spent piecing it all back together.
    Nov. '19 attempted myomectomy (vaginal approach) failed. 2nd surgery using laparoscopic method in Jan '20 is successful.
    April '20 --> June '20, natural IUIs, all BFN.
    July? saline ultrasound and bubble test demonstrate open tube
    July '20 clomid cycle cancelled for thin lining
    Aug-Oct, 3 femara cycles, all BFN
    RE referral. While waiting to set up an appointment Nov-Jan,I continue with natural cycles and ICI, using a known donor, BFN...
    Jan '21 more bloodwork, AMH is worse (.30), FSH high albeit not catastrophic at 13.2. hysteroscopy all good. "looks cozy!" says the RE.
    Feb '21, injectables (menopur, novarel), iui, BFN (doc said the frozen donor sperm sample had the "best numbers she'd ever seen!")
    Mar '21, injectables, iui cancelled due to lack of follicles, converted to at home-insem. BFN
    May '21, first IVF round cancelled due to cyst.
    July '21 IVF: standard antagonist. 225menupur/225gonal-f/cetrotide/5000u trigger, AFC 7; 6 days of stims. 8 eggs retrieved, 7 mature, 5 fertilize, 4 made it to blast. 3 are 4AB, 1 is 4BB. PGT-A results all abnormal.
    Oct '21 somewhat improved AMH (.51) and significantly improved FSH (8.9). Maybe it's all the pills I swallow.
    Dec -21, standard antagonist. 225menupur/225gonal-f/cetrotide/5000u trigger, AFC 5; 11 days of stims. retrieval yields 5, 4M, 2 reach day-6 blast (4AB & 4BB). 1 low-level mosaic (chr. 3 deletion), 1 complex abnormal.
    Feb '22 FET (low-level mosaic): CP.
    May '22 egg retrieval, lupron flare protocol. HGH priming for 1 month before stims; md lupron 20/20u daily; menopur 225, follistim 225, 10k trigger after 8 days of stims; AFC 10; 13 retrieved; 10 mature; 8 fertilized. All frozen at 2PN for later thaw, grow, and biopsy.
    July '22 egg retrieval same protocol: 9 days of stims; AFC 8; 10 retrieved, 8 mature, 4 fertilized and frozen.
    Sept '22 ER same protocol: AFC 10; 12 retrieved, 11 mature, 11 fertilized.
    From the 3 retrievals, 7 survived to day 5-6 blastocyst, from which I have 2 normal embryos!
    Jan 20, Fully medicated FET, baby aspirin, dexamethasone, acupuncture, and as much woo as I can stand (which isn't very much). BFN.
    July 23, Natural FET + baby aspirin. BFN.
  • @gingermama29 so freeing, it's great! So glad you had a great consult!

    @kiki047 I did see one other person around in the Infertility board who did get her period only 4 days after ER so it is possible.

    @optimistgardener I made sure not to be really detailed like just said I did a biopsy instead of specifying uterine biopsy. Spared people some of the grosser details lol. Not sure what I would do about the meds. Those gonal-f pens are freaking expensive! I've mentioned this before - my ER we used only 5000 units to keep risk of OHSS down. The original plan had been 10,000. DH and I busted out laughing at your response to the GTKY 🤣. Because that was kind of the case! Not so much a caramel apple (although my mom brought me a 3 pack that I devoured last week) but a regular apple cut up and dipped in peanut butter and honey was what I was hungry for 🤣
    *TW* History:
    Me: 34 DH: 36 | Together since 2007 | Married July 2016

    TTC #1 since 7.2017
    Dx: low morph (1%), ANA positive, low decidualization score, high TSH and testosterone, histone antibodies

    IUI #1-3 all BFN
    IVF #1 | 6.11.19 | 24R, 17M, 15F, 6B, PGT-A tested - 5 normal, 3 girls & 2 boys
    FET #1 | 9.10.19 | BFN "I know you, but we've never met. I'm with you, but I don't know your name"
    RPL, Receptiva, & ERA testing | all normal/negative, recommended going on gluten and dairy free diet for next FET
    FET #2 | 3.31.20 | Opted to cancelled due to pandemic, continued diet and tried naturally over the summer
    2nd Opinion with another RE | 8.20.20 | Not immune to measles (received 1 dose); SA results similar to 2 years ago; decided to move forward with FET #2 redo at start of next cycle
    Surprise natural BFP! | 9.22.20 | MC 10.23.20 at 8 weeks
    TTCAL naturally | starting 11.22.20

    Initial consultation with Reproductive Immunologist | 9.14.21
    Decidualization score biopsy | 10.1.21 | abnormal - low score of 1; endometrial scratch recommended and progesterone supplementation
    Saline sono | 10.15.21 | normal
    Bloodwork | 10.21.21 high TSH, high testosterone, positive for anti-nuclear antibodies and histone antibodies, high protein S, multiple genetic mutations
    BFP! | 11.3.21 | EDD 7.14.22 B) | biopsy provided same effect as endometrial scratch; added supplemental progesterone and estrogen, prednisone, levothyroxine, and MTX Support to maintain pregnancy
    DS born 7.19.22 after induction


    TTC #2 begins 6.2023
    Consultation with RI | 6.6.23
    Saline sono, endometritis biopsy, skin & eye check | all normal
    Labs | high TSH, Factor XIII mutation, high %CD56
    Follow up | 8.8.23 | prescribed metformin, prednisone, plaquenil, and levothyroxine
    Repeat labs after 3 weeks on meds
    Follow up | 11.9.23 | Green light!, increase in prednisone, added lovenox
    Repeat labs in 8 weeks
    Follow up | 1.16.24 | Green light continues
    TTC put on pause
  • @inthewoods23 hahahaa i knew it!
    History
    I am doing this on my own. Left ovary and fallopian tube removed due to cyst/necrosis just after birth. Right ovary and tube still purport to function.
    Began TTC in Aug '18 @ age 35
    5 or 6 (or 7?!) cycles using frozen donor sperm, ICI. All BFN
    Mar-Jun '19 IUIs, all BFN
    Began process of referral for RE in spring of '19, blood tests confirm low AMH (.54) but all else is good.
    May '19 HSG shows open tube, but ultrasound suggests fibroids
    MRI in June '19 confirms two large fibroids, one growing through wall of uterus
    In June '19 I move from California to Oregon, disrupting my insurance, referrals, etc. 5 months spent piecing it all back together.
    Nov. '19 attempted myomectomy (vaginal approach) failed. 2nd surgery using laparoscopic method in Jan '20 is successful.
    April '20 --> June '20, natural IUIs, all BFN.
    July? saline ultrasound and bubble test demonstrate open tube
    July '20 clomid cycle cancelled for thin lining
    Aug-Oct, 3 femara cycles, all BFN
    RE referral. While waiting to set up an appointment Nov-Jan,I continue with natural cycles and ICI, using a known donor, BFN...
    Jan '21 more bloodwork, AMH is worse (.30), FSH high albeit not catastrophic at 13.2. hysteroscopy all good. "looks cozy!" says the RE.
    Feb '21, injectables (menopur, novarel), iui, BFN (doc said the frozen donor sperm sample had the "best numbers she'd ever seen!")
    Mar '21, injectables, iui cancelled due to lack of follicles, converted to at home-insem. BFN
    May '21, first IVF round cancelled due to cyst.
    July '21 IVF: standard antagonist. 225menupur/225gonal-f/cetrotide/5000u trigger, AFC 7; 6 days of stims. 8 eggs retrieved, 7 mature, 5 fertilize, 4 made it to blast. 3 are 4AB, 1 is 4BB. PGT-A results all abnormal.
    Oct '21 somewhat improved AMH (.51) and significantly improved FSH (8.9). Maybe it's all the pills I swallow.
    Dec -21, standard antagonist. 225menupur/225gonal-f/cetrotide/5000u trigger, AFC 5; 11 days of stims. retrieval yields 5, 4M, 2 reach day-6 blast (4AB & 4BB). 1 low-level mosaic (chr. 3 deletion), 1 complex abnormal.
    Feb '22 FET (low-level mosaic): CP.
    May '22 egg retrieval, lupron flare protocol. HGH priming for 1 month before stims; md lupron 20/20u daily; menopur 225, follistim 225, 10k trigger after 8 days of stims; AFC 10; 13 retrieved; 10 mature; 8 fertilized. All frozen at 2PN for later thaw, grow, and biopsy.
    July '22 egg retrieval same protocol: 9 days of stims; AFC 8; 10 retrieved, 8 mature, 4 fertilized and frozen.
    Sept '22 ER same protocol: AFC 10; 12 retrieved, 11 mature, 11 fertilized.
    From the 3 retrievals, 7 survived to day 5-6 blastocyst, from which I have 2 normal embryos!
    Jan 20, Fully medicated FET, baby aspirin, dexamethasone, acupuncture, and as much woo as I can stand (which isn't very much). BFN.
    July 23, Natural FET + baby aspirin. BFN.
  • Wow - this thread today! 


    *flexes* Okay, here goes: 

    @hanshotfirst77 it's wonderful that you managed to get your testing done! And the SHG lined up! Hopefully it won't be long until you can start treatment. 

    @kiki047 holy smokes! I hope YH doesn't feel so bad now since it turns out your MII > fert conversation is actually so much better. Here's to hoping that many of them make it to Day 5/6. Crossing everything for you. Btw, I do definitely appreciate your sensitivity about us DOR or DOR-like ladies. I'm really hoping @bumblebee0210 is right that what we lack in egg quality/quantity, we'll make up in uterus awesomeness. As for your Q about have you started your period, you likely did. As I recall, you did a Lupron only trigger? When I cancelled my ER back in June, they had me do a Lupron trigger to "pop" all the follicles, and I got my period 4 days early. The nurse told me that while it's not usual, it's not unexpected when it's a Lupron only trigger. 

    @bumblebee0210 dude! I CANNOT believe that just like that you're prepping for your transfer and that it's NEXT WEEK! Like WOAH?! Where did the time go? Remember when you were all #BitterHag and saying things like "you'll be back here for your #2 and I'll still doing ER #200." Well, THAT didn't happen! Youppie! Also, once again, can I just pray that your ute is good? Thinking thick for you. 

    @shortstack930 That's awesome that you ended up with 5 days off after transfer! I feel like that's another sign of planets aligning. Good luck with surviving the night shifts though. Maybe they'll help make the time go by quicker! I'm in favor of you testing on Sunday, but like, I understand if you decide not to. :P My opinion is not important. 

    @inthewoods23 first of all, the meme for this week's thread is 💯. BRAVO! Also, LOL @optimistgardener finding you out about your GTKY. Hehe. I hope you satisfied your craving. Also, I'm so happy your insurance saga is finally over. What does "I should be on an immune protocol" mean? Are you expecting results back in time for next cycle (if you even need it?) Are you going continue TTC "unassisted" for a while? Also, I'm SO happy that you're feeling some relief about opening up on FB. I'm not brave enough to do that on FB because I have a bunch of FB friends who are from my former Church on it, and Christian Orthodox, like Catholics, do not approve of IVF (more on that later). **TW** I did, however, post something about my CP in a friend Slack group. Mostly because I was raving about the fact that I got the booster shot on Friday, having qualified because of my recent loss. **End TW**

    @walkawaynee Others have already weighed in, but my thoughts are the same. Since you're DOR, it's likely that you won't feel like you've been hit by an 18-wheeler after your ER. But it would be nice if the theme park outing is 2+ days after the ER. Also, I hope all the stuff that kept you away last week has sorted itself out. 

    @gingermama29 HIIIIII! Welcome back. So happy that you had what sounds like an amazing first meeting with your RE! Woot! Your plan going forward sounds excellent. Good luck with that Metformin. By the sounds of it, it's NAS-TAY stuff. Remind me, is IVF an option of your down the road? 

    @knockupthestock First of all, welcome back to TB's TTGP. I read your post last week about the horrible side-effects of dexamethasone and I cried deep inside. Gah! I hope those side effects go away quickly once you're off of it. I'm also kind of happy to have read about it, since at one point, I was asking my RE to put me on a retrieval protocol that included dexamethasone. It didn't happen in the end, and now I feel like I dodged a bullet. Good luck with all the baby dancing! 

    @optimistgardener FWIW, if you run out of Gonal-F, I can expedite some I will likely have left over (if you're into that). I know that you're ordering from overseas, so with the shipping delays, this might be an option to consider. I don't actually have experience with lower hCG trigger. Last cycle I had both an hCG trigger + double Lupron trigger (12 hours apart). And I think my hCG amount was only 2500IU. Also, re: your better than normal blood work results, re: FSH at least, I think that it's still the highest one you've gotten that "rules the lot." As you get older, it tends to jump around from month to month. I got all excited when last December 2020, my FSH came back at 6.7 or something like that, after being 9.23 in March 2020. And then in March 2021, it was up to 13. But never mind me, I'm just here, POOPING ON YOUR PARTY! 

    Phew...I done it! Taking the dog out for a walk now, and then will post my update. 
    MY CHART
    TTC History
    TTC#2
    Me: 40.5; MH: 39 | Met 02/2009 | Started Dating 08/2017 | Married 02/02/2020
    TTC #2 ... preparing as of March 2024


    TTC #1
    Me: 36, MH: 34 | Met 02/2009 | Started Dating 08/2017 | Married 02/02/2020
    TTC #1 02/2020 - 07/2022
    2009 | Dx PCOS; likely a misdiagnosis
    07/14/20 | Dx Hashimoto's Thyroditis
    07/21/20 | 1st RE appointment
    07/2120 - 08/20/20 | so much testing; no signs of PCOS
    08/20/20 | Dx Unexplained; AMA
    09/08/20 | IUI #1 Clomid + Trigger + Prometrium | BFN
    09/30/20 | Urology consult; more testing required
    10/2020 | Clomid + OPK + TI + Prometrium | BFN
    10/26/2020 | Starting 2nd IUI cycle, with Letrazole and with a new RE / different clinic
    11/03/2020 | New Dx "poor egg quality"; IUI cancelled in favor of Trigger + TI + Prometrium | BFN
    11/26/2020 | Combo IUI (Clomid + Menopur) + Trigger + Prometrium | BFN
    12/20/2020 | Combo IUI (Clomid + Gonal-F) + Trigger | IUI Cancelled due to thin lining; TI only | BFN
    01/14/2021 | Combo IUI (Letrazole + Menopur) + Trigger | BFN
    02/06/2021 | Switched to a new RE (TEW) ; trying naturally until we complete additional testing 
    03/14/2021 | Hybrid Double IUI, with Zymot (Letrazole, Gonal-F) + Trigger + Endometrin | Ovulated 4 mature eggs but still a BFN ☹️
    04/07/2021 | Natural cycle while we regroup | BFN
    04/09/2021 | Employer announces fertility benefits starting 05/01/2021! | Search for a new doctor who accepts insurance
    05/10/2021 | New RE consult & plan for IVF
    05/13/2021 | Mid-luteal IVF cycle #1 interrupted; had to get cancer genetic screening done to make sure I didn't have the same SDHA gene mutation as MH. 
    06/10/2021 | Aygestin priming IVF cycle #1; opted to Cx after 9 days of stims since only 5-6/12 follicles responded
    07/26/2021 | Attempt #2 at IVF cycle #1 (mid-luteal start): 8 retrieved, 8 MII, 6 fert (1 PN3), 3 Day 5 & 6 blasts: 3AA, 3AA, 6AB; 3 euploid
    08/09/2021 | Rest cycle / unmedicated TTC | Shockingly, a BFP! EDD: 5/25/202 | CP at 4w4d
    09/23/2021 | IVF cycle #2 (mid-luteal start): 14 retrieved, 13 MII, 11 fert, 5 Day 5 & 6 blasts: 2 x 3AA, 2 x 3AB, 3BB; 2 euploid
    11/12/2021 | IVF cycle #3 (mid-luteal start): cancelled due to ovaries being on vacation
    12/20/2021 | Rest cycle / unmedicated TTC + Pregmune Immunology Testing; BFN
    01/22/2022 | Rest cycle / unmedicated TTC + understanding uncovered immunological issues; BFN
    02/18/2022 | Mock transfer cycle! ERA, ReceptivaDx, EMMA/ALICE; start Prednisone to address NK activity
    03/16/2022 | Final, "Hail Mary" super-ovulation + TI cycle before FET; BFP! EDD: 12/21/2022 | MMC 05/08/2022
    05/20/2022 | D&C; recovering... 
    06/21/2022 | Trying naturally until October 2022
    07/21/2022 | BFP! EDD 04/02/2023; 👦🏼 born on 4/5/2023


  • edited October 2021
    First off, last week was such a write off. In addition to work being crazy as I ready myself to manage 2 people PLUS hiring 2 more ppl (for which I am doing the sourcing), I decided to take a couple of prof dev courses that fell roughly after hours. That, plus starting my stims, plus starting treatment for whiplash from the stupid-a$$ rear-end collision the week before, left me exactly negative 50 points in energy and thus with no capacity to do anything more than lurk here. 

    I feel like I'm being a bad-forum-friend to @keikilove. I felt so many feels reading your post last week. Yet here I am, not being able to do anything more than just send you virtual support. 

    Diagnosis (if you've been):  Official: "unexplained"; Unofficial: Hashimoto's, AMA, wandering sperm

    Status (WTO/TWW/TTA): technically TWW

    What are you doing this cycle? (Testing? Treatment?): SHOTS SHOTS SHOTS SSSSSSHOTS! (a.k.a. stims for ER #2). 

    How are things going?:  You ready for this? I'm gonna spoiler A LOT so brace yourselves. 

    First of all, I'm sure you'll wondering, but yes, we survived the "atmospheric river" and "bomb cyclone" that hit SF in the last 48 hours. More about the weather in spoiler.
    Lucky for us (us being MH and I), we live on the tallest peak in SF, and last I checked, water still runs downhill. But even our storm drains were overflowing by the time rain ceased this AM. Also, I was out and about most of yesterday, and saw the situation get worse as the day went on. I am lucky that I have a large-a$$ SUV which made me feel very safe, but there were still breathless moments as cars threw buckets of water into the windshield that left me momentarily blind because the wipers couldn't keep up. 

    Weather aside, IT'S HERE. My 2nd ER cycle. Looks like a bit of Letrazole did the trick. I went in for my "baseline" on Thursday (in quotes because my coordinator was convinced that my positive OPK from prior Sunday had been a "false positive" since Letrazole tends to do that. And in my mind, yeah OK... I KNOW what a positive OPK looks like and I'm telling you I ovulated. And of course, I had. So, at baseline, I had...
    14 follicles, 7 on each side. This is 2 more than I've had since March 2021. Since then, it had been consistently 12 follies. 
    The best point in that u/s was that all follicles looked to be about the same size. And, if some of you can recall, I had previously complained that even at baseline, 2-3 follicles always look bigger. This is something even my RE had remarked upon. 

    So, today I had my first f/u ultrasound (Day 5) and I remain cautiously optimistic. 
    13 of my follicles were in the 6-10mm range. And a few more below that. Doc said that I can expect the smallies to remain too small to catch up, and it's likely that we'll need to let 2-3 of the biggies go, in favor of the 10 or so middles ones. 
    Overall, it seems like the cancelled cycle in June + the first cycle in July gave my ovaries a much-needed kick in the "eggs". Of course, now I'm freaking out since I've been quite liberal with my wine consumption between the 2 egg retrievals, including last week (into the early days of the stim cycle) because... honestly... last week sucked balls and I just wanted to drink some good wine, which I did. I hope that I won't regret that decision. Being good now. MH also hasn't been super on the ball with his vitamins. So, we're both guilty of straying. 

    I have also managed to eff up my HGH, due to "false confidence" in my ability to execute my shots like I've done it a million times. More on that in spoiler too. 
    The first night I mixed my Omnitrope and PROCEEDED TO LEAVE THE MIXTURE OUT. The next night, I realized what I'd done, and frantically tried calling the pharmacy. This was at 8:45pm, so no one answered. So, then, I also realized that I had thrown out the remaining Omnitrope from my July cycle, into the same baggie, and I was also left wondering if I had also injected myself not only with Omnitrope that had been outside the fridge for 24 hrs, but also one that had been mixed 60+ days ago. Argh. Anyways, I ended up giving myself another dose of Omnitrope, from a different vile. The next day I got hold of the pharmacist and they told me that manufacturer doesn't have any guidance for leaving mixed meds out overnight. So I called the clinic, and they consulted with the doc on call, and told me to discard the vial that had been left over overnight, and mix another. So, I basically threw about about $175 of meds (I have to pay for this one OOP), just because I got too cocky. 

    Anyways, I'm back into the clinic on Thursday for another ultrasound/bloodwork, and then again sometime on the weekend, with an ER likely happening Monday-Wednesday next week. 

    Also, as I mentioned above, I managed to get a Covid booster on Friday. I actually had the least amount of reaction to it, then to the first 2 shots. I'm happy I got that out of the way. 

    I've also been catching up on my TEW shows, and have some information for you: 

    @laura-kay, I'm not sure if you're still lurking, but you might want to check this one out: 

    @optimistgardener@bumblebee0210: for my fellow PGT-curious ladies, I listened to this great mini-show of hers yesterday and 
    also started following https://www.instagram.com/meaghandoylegc/ on instagram thereafter. @kiki047 the show's guest hails from your neck of the woods! 🇨🇦Girls you gotta check out some of her IG posts. They're BOMB. I haven't listened to any yet, but I will. Just gonna drop this one here for those our you who are like TL;DR lady... get to the effing point!



    Finally, last night I read an interesting WaPo article on religious take on IVF. I've been keeping quiet about our IVF journey on FB primarily because I have a lot of ppl from my former parish there, and it's against Orthodoxy to do IVF. It's also against Catholicism. However, this article looked at how ppl of faith are managing, and most are just doing that "in secret". The article also polled people of faith, asking if they considered IVF moral/immoral/not a moral issue and about 80% of Catholics say that it's not a moral issue. As an Orthodox, that's what I think too, but I'm not ready to reconcile my own beliefs with those of my chosen faith just yet. Oh, and also, did you know that Islam permits IVF! I was frankly shocked, but happily so. 

    Any questions?: How do we feel about nearly-expired/just expired medication? I realized that I have some Ganirelix that expires Oct 26, 2021. This is antagonist (similar to Cetrotide) that I purchased back in Feb when I was still OOP and was "stocking up" on meds. I start my antag on Wed, so the lot I have will have been expired 1 day then, and then +1 each day after. I kind of want to use it, but at the same time, the antagonist isn't something I want to eff with. Thoughts? 

    GTKY: What's your favorite topping for a caramel apple? If you're not a fan of caramel apples, then what is your favorite fall treat? 
    I don't think I've ever had a caramel apple and I don't think I would want to. I'm not a particularly sweet person, but like @shortstack930 I'll take a homemade pumpkin pie with a gluten free crust. I'm going to try to make a dairy-free pumpkin pie this year. Last year I found a great gluten free crust recipe; this year, I discovered a great coconut yogurt I'll attempt to use in lieu of evaporated milk for the stuffing. 
    MY CHART
    TTC History
    TTC#2
    Me: 40.5; MH: 39 | Met 02/2009 | Started Dating 08/2017 | Married 02/02/2020
    TTC #2 ... preparing as of March 2024


    TTC #1
    Me: 36, MH: 34 | Met 02/2009 | Started Dating 08/2017 | Married 02/02/2020
    TTC #1 02/2020 - 07/2022
    2009 | Dx PCOS; likely a misdiagnosis
    07/14/20 | Dx Hashimoto's Thyroditis
    07/21/20 | 1st RE appointment
    07/2120 - 08/20/20 | so much testing; no signs of PCOS
    08/20/20 | Dx Unexplained; AMA
    09/08/20 | IUI #1 Clomid + Trigger + Prometrium | BFN
    09/30/20 | Urology consult; more testing required
    10/2020 | Clomid + OPK + TI + Prometrium | BFN
    10/26/2020 | Starting 2nd IUI cycle, with Letrazole and with a new RE / different clinic
    11/03/2020 | New Dx "poor egg quality"; IUI cancelled in favor of Trigger + TI + Prometrium | BFN
    11/26/2020 | Combo IUI (Clomid + Menopur) + Trigger + Prometrium | BFN
    12/20/2020 | Combo IUI (Clomid + Gonal-F) + Trigger | IUI Cancelled due to thin lining; TI only | BFN
    01/14/2021 | Combo IUI (Letrazole + Menopur) + Trigger | BFN
    02/06/2021 | Switched to a new RE (TEW) ; trying naturally until we complete additional testing 
    03/14/2021 | Hybrid Double IUI, with Zymot (Letrazole, Gonal-F) + Trigger + Endometrin | Ovulated 4 mature eggs but still a BFN ☹️
    04/07/2021 | Natural cycle while we regroup | BFN
    04/09/2021 | Employer announces fertility benefits starting 05/01/2021! | Search for a new doctor who accepts insurance
    05/10/2021 | New RE consult & plan for IVF
    05/13/2021 | Mid-luteal IVF cycle #1 interrupted; had to get cancer genetic screening done to make sure I didn't have the same SDHA gene mutation as MH. 
    06/10/2021 | Aygestin priming IVF cycle #1; opted to Cx after 9 days of stims since only 5-6/12 follicles responded
    07/26/2021 | Attempt #2 at IVF cycle #1 (mid-luteal start): 8 retrieved, 8 MII, 6 fert (1 PN3), 3 Day 5 & 6 blasts: 3AA, 3AA, 6AB; 3 euploid
    08/09/2021 | Rest cycle / unmedicated TTC | Shockingly, a BFP! EDD: 5/25/202 | CP at 4w4d
    09/23/2021 | IVF cycle #2 (mid-luteal start): 14 retrieved, 13 MII, 11 fert, 5 Day 5 & 6 blasts: 2 x 3AA, 2 x 3AB, 3BB; 2 euploid
    11/12/2021 | IVF cycle #3 (mid-luteal start): cancelled due to ovaries being on vacation
    12/20/2021 | Rest cycle / unmedicated TTC + Pregmune Immunology Testing; BFN
    01/22/2022 | Rest cycle / unmedicated TTC + understanding uncovered immunological issues; BFN
    02/18/2022 | Mock transfer cycle! ERA, ReceptivaDx, EMMA/ALICE; start Prednisone to address NK activity
    03/16/2022 | Final, "Hail Mary" super-ovulation + TI cycle before FET; BFP! EDD: 12/21/2022 | MMC 05/08/2022
    05/20/2022 | D&C; recovering... 
    06/21/2022 | Trying naturally until October 2022
    07/21/2022 | BFP! EDD 04/02/2023; 👦🏼 born on 4/5/2023


  • gingermama29gingermama29 member
    edited October 2021

    @knockupthestock yes this is my first time taking metformin. My RE did warn me about the GI side effects and is easing me into the dosage. I’m starting with 1 pill a day for 2 weeks and then increasing to 2 and then eventually the 3. Yay for follicle growth and triggering! FX for you!

    @kiki047 oooh good to know about the timed release option. I’m glad that combo has made a difference for you! Here’s hoping for the same here.

    @optimistgardener oh man your ER is going to be here so soon! That annoying little voice is the worst! 

    @acleverusername yes IVF is definitely an option down the road. I’m incredibly fortunate to have insurance that covers 3 rounds in full. But my RE and I agreed that we’d rather save that option to use if the other treatments don’t work. She’s optimistic about medicated cycles since I’ve gotten KU twice on them. Hopefully monitoring and the added medication will be the difference maker for a THB. Glad everything you’ve gone through in the last few months gave your ovaries the kick in the eggs they needed (love that expression 😂). FX for good growth in your follies for your next appointment! So excited your ER is coming up! 

  • @acleverusername I totally value your opinion! I may test Sunday just so that I have time to sleep on it if it's not good news. That weather sounds crazy! I'm glad you guys are safe. I am still super optimistic for your ER. I'm sorry you've been dealing with the religious aspect of things. We switched from Catholic to Methodist years ago and it still upsets me that IVF is so frowned upon in the Catholic faith. I did know that about Islam though! One of my good friends is Muslim and both her sister and sister-in-law have done IVF.
    TTC History
    Me: 35 DH: 34
    Married 07/2012
    DD born 07/2014
    DD2 born 10/2018
    DS born 10/2022

    IF history:
    TTC #2 since January 2016
    June-Aug 2017: 3 IUIs w/Clomid = BFN
    Sept 2017: Dx w/Endometriosis
    Oct 2017: IUI w/Letrozole = BFN
    Nov 2017: IUI w/Letrozole = BFN
    Dec 2017: pre-IVF testing
    Jan-Feb 2018: IVF--17 eggs retrieved, 13 fertilized, 9 frozen and 1 transferred on 2/10 = BFP on 2/19!!! EDD 10/29/2018
    FET Oct 2021: BFP on 10/31! MC at 5 weeks
    FET Feb 2022: BFP on 2/15! EDD 10/29/22


  • So much here. Just wanted to pop in and say @kiki047 I have always had a short-ish luteal phase, and when I did a lupron trigger, I got my period 5 days past ER (For HCG it was always 10-11). So I don't think 3 days is super weird. Just make sure the clinic is ready to start you up again! You are basically doing duostim because it's ~5 days past ER start anyway.  
    TTC History
    TTC #1 Sep 2017-Sep 2018 
    BFP 11/30/2017 | MMC 12/31/2017
    BFP 6/22/2018 | CP 6/27/2018
    BFP 10/5/2018 | EDD 6/14/2019
    Baby girl born 6/19/19

    TTC #2 May 2020-November 2021
    BFP 7/18/2020 | MonoDi Twins | MMC 9/10/2020
    BFP 11/7/2020 | CP 11/9/2020
    RE Consult January 2021 | Dx "borderline DOR"/RPL
    IVF with PGT:
    Standard Antagonist:
    ER #1 3/27/2021 7R | 5M | 3F | 2B | 1 PGT-A Normal, 1 low-level mosaic
    ER #2 4/22/2021 10R | 7M | 3F | 2B | 0 normal, 2 aneuploid
    ER #3 5/19/2021 2R | 1M | 0F
    Estrogen Priming Antagonist:
    ER #4 7/10/2021 5R | 4M | 3F | 1B | 1 PGT-A Normal
    Duostim  (Standard Antagonist):
    ER #5 9/22/2021 13R | 11M | 8F | 5B | 2 PGT-A Normal, 1 low-level mosaic, 2 aneuploid
    ER #6 10/9/2021  9R | 6M | 4 F | 1B | 1 aneuploid
    FET #1  11/5/2021 | EDD 7/24/2022
    Baby boy born 7/19/22

    TTC #3 since May 2023 (ntnp)
    IVF Started Fall 2023 (Standard Antagonist)
    ER #7 10/6/2023 | 9R | 6M | 5F | 3B | 2 aneuploid, 1 high-level mosaic
    ER #8 10/31/2023 | 5R | 4M | 3F | 1B | 1 PGT-A Normal
    FET #2 11/27/23 | CP (bHCG = 8)
    FET #3 planned Jan 2024



  • edited October 2021
    @acleverusername thank you so muchg for your generosity. and also for your reality check on FSH. yeah, I've heard the same thing about FSH. I just... want a little good news to tide me through, and in combo with my other slightly more decent numbers it's a tempting picture to cling to. :) let's stay in touch on the gonal-f. i'll pm you if it seems like i might need to take you up on your offer! re: expired meds, my own inclination and also the opinion of my RE is that the drugs are probably still just fine unless they're like, really expired. being a few days past the date is not a big deal. those expiration dates have serious padding built into them. Re: religious justifications for or condemnations of IVF, I have always had a kind of curiosity from afar as to how traditions address these things. Speaking as someone for whom it is tangentially I guess relevant to my professional field, I am not surprised that Islam permits IVF. I just did a little bit of digging on the topic and it appears to be roughly the consensus (because there is not, as there is in Christianity, an overriding authority on any given topic, just a consensus that emerges amongst scholars) that IVF is fine, but people frown on egg adoption and sperm donation. OTOH, in Shi‘a Islam, which allows for temporary or "muta‘a" marriage, there is a convenient workaround for egg adoption that involves the husband temporarily marrying the donor. If people are for any reason interested in this particular rabbit hole, there's a freely available paper on (dated 2005) on the princeton U website.
    History
    I am doing this on my own. Left ovary and fallopian tube removed due to cyst/necrosis just after birth. Right ovary and tube still purport to function.
    Began TTC in Aug '18 @ age 35
    5 or 6 (or 7?!) cycles using frozen donor sperm, ICI. All BFN
    Mar-Jun '19 IUIs, all BFN
    Began process of referral for RE in spring of '19, blood tests confirm low AMH (.54) but all else is good.
    May '19 HSG shows open tube, but ultrasound suggests fibroids
    MRI in June '19 confirms two large fibroids, one growing through wall of uterus
    In June '19 I move from California to Oregon, disrupting my insurance, referrals, etc. 5 months spent piecing it all back together.
    Nov. '19 attempted myomectomy (vaginal approach) failed. 2nd surgery using laparoscopic method in Jan '20 is successful.
    April '20 --> June '20, natural IUIs, all BFN.
    July? saline ultrasound and bubble test demonstrate open tube
    July '20 clomid cycle cancelled for thin lining
    Aug-Oct, 3 femara cycles, all BFN
    RE referral. While waiting to set up an appointment Nov-Jan,I continue with natural cycles and ICI, using a known donor, BFN...
    Jan '21 more bloodwork, AMH is worse (.30), FSH high albeit not catastrophic at 13.2. hysteroscopy all good. "looks cozy!" says the RE.
    Feb '21, injectables (menopur, novarel), iui, BFN (doc said the frozen donor sperm sample had the "best numbers she'd ever seen!")
    Mar '21, injectables, iui cancelled due to lack of follicles, converted to at home-insem. BFN
    May '21, first IVF round cancelled due to cyst.
    July '21 IVF: standard antagonist. 225menupur/225gonal-f/cetrotide/5000u trigger, AFC 7; 6 days of stims. 8 eggs retrieved, 7 mature, 5 fertilize, 4 made it to blast. 3 are 4AB, 1 is 4BB. PGT-A results all abnormal.
    Oct '21 somewhat improved AMH (.51) and significantly improved FSH (8.9). Maybe it's all the pills I swallow.
    Dec -21, standard antagonist. 225menupur/225gonal-f/cetrotide/5000u trigger, AFC 5; 11 days of stims. retrieval yields 5, 4M, 2 reach day-6 blast (4AB & 4BB). 1 low-level mosaic (chr. 3 deletion), 1 complex abnormal.
    Feb '22 FET (low-level mosaic): CP.
    May '22 egg retrieval, lupron flare protocol. HGH priming for 1 month before stims; md lupron 20/20u daily; menopur 225, follistim 225, 10k trigger after 8 days of stims; AFC 10; 13 retrieved; 10 mature; 8 fertilized. All frozen at 2PN for later thaw, grow, and biopsy.
    July '22 egg retrieval same protocol: 9 days of stims; AFC 8; 10 retrieved, 8 mature, 4 fertilized and frozen.
    Sept '22 ER same protocol: AFC 10; 12 retrieved, 11 mature, 11 fertilized.
    From the 3 retrievals, 7 survived to day 5-6 blastocyst, from which I have 2 normal embryos!
    Jan 20, Fully medicated FET, baby aspirin, dexamethasone, acupuncture, and as much woo as I can stand (which isn't very much). BFN.
    July 23, Natural FET + baby aspirin. BFN.
  • @kiki047, holy plot twist! That is amazing!  Also yeah, siggies evaporated for me too. I noticed that mine was missing last week, but could still see some other people's. Now all of them are gone. I just assumed they'll eventually come back.

    @bumblebee0210, FX all goes smoothly Thurs and you can pin down a transfer date, and that you get good news on your blast!

    @walkawaynee, others have chimed in, but I'll agree and say it depends on how soon after the ER.  Mine was 2 days before Thanksgiving and I was so bloated and sore, just moving around my in-laws house and eating was enough for me that day, but by the weekend I was feeling fine.  Of course everyone responds differently and you may be totally fine a day later or sooner, but I would plan to be a little sore for at least a couple of days. 

    Glad the consult went well @gingermama29 and you were able.to develop a plan!

    @acleverusername, glad your cycle is going well and I'll be sending you all of the good egg vibes!!  Also, after that week, I think some good wine was more than called for!


    Diagnosis (if you've been): primarily MFI + ovulatory dysfunction 

    Status (WTO/TWW/TTA):  FET

    What are you doing this cycle? (Testing? Treatment?):  transfer is scheduled for Weds PM. 

    How are things going?:  things are good. H last night said he can't believe the transfer is already up this week because "I feel like you haven't been doing the shots that long, it's only been like a month." Idk about him, but a month is plenty of prep time in my book, lol.

    Other than the quickly approaching FET, nothing interesting. I can't remember who it was now, but a few weeks ago someone mentioned their RE's office not being able to find the uterus/ovaries.  Funny enough, the med student sitting in on my lining check couldn't track down my ovaries last week either and even my RE had a hard time finding them.  We know the L one is adhered to the back of my uterus, so that one always causes trouble, but I never really thought about my R one before.  Given the issues it caused during my ER and its habit of camping out in hard to reach places, I'm starting to wonder if it's not stuck to some ish too.  

    Any questions?:  not at the moment.

    GTKY: What's your favorite topping for a caramel apple? If you're not a fan of caramel apples, then what is your favorite fall treat?
    I'm a standard rainbow (or fun shaped) sprinkles person. 

  • @optimistgardener am I really that easy to read :joy:

    @acleverusername I never did satisfy that craving yesterday lmao. I will have to today! When I say immune protocol, I mean I'll be put on immunosuppressants based on what my lab work says. As an example - if my immune system is overactive and attacking embryos preventing from them implanting, the immunosuppressants should calm my system down so that it doesn't attack embryos. I'm technically supposed to be TTA but when not even a hint of pregnancy has happened all but 1 time, I think we're very unlikely to end up with a surprise. I think we'll have all our results sometime in next month's cycle but we might not get clearance to start trying in December. I believe the RI usually likes to see how lab work changes after being on the new meds for a few weeks. But yes, we're going to be full steam ahead on trying naturally on this protocol. And if it works, we'll have to start thinking about what to do with our 3 embryos still sitting on ice. Which actually.... some of my family is quite Catholic and very pro-life and I wonder what their opinions would be towards what we do with these embryos. I wonder if they've been secretly judging me for going through IVF. I think we can donate the embryos for science. I'm having a hard time at the idea of putting them up for embryo adoption. Like how freaked out am I going to be with a full biological child out there should I come across them some day. I think you can do these types of adoptions as open, but it might depend on the clinic. We'll cross that bridge when we get to it. And girl you have been through a lot in the past week!

    Also....
    Lmfao Shots GIF - Lmfao Lil Jon Shots - Discover amp Share GIFs

    This talk of IVF and religion is all very interesting. Is there anything specific about it, or does it all fall under the bucket of "you're playing god by doing IVF"? Is this where someone makes the argument that if they think IVF is wrong, then they shouldn't get cancer treatment because it's also medical science? :#

    @zwink1 I expect I will have similar "oh we're already here?" feelings should we get around to doing a round 2 with the RI. IF stuff goes so much faster when you've had success already :D of course it feels short!
    *TW* History:
    Me: 34 DH: 36 | Together since 2007 | Married July 2016

    TTC #1 since 7.2017
    Dx: low morph (1%), ANA positive, low decidualization score, high TSH and testosterone, histone antibodies

    IUI #1-3 all BFN
    IVF #1 | 6.11.19 | 24R, 17M, 15F, 6B, PGT-A tested - 5 normal, 3 girls & 2 boys
    FET #1 | 9.10.19 | BFN "I know you, but we've never met. I'm with you, but I don't know your name"
    RPL, Receptiva, & ERA testing | all normal/negative, recommended going on gluten and dairy free diet for next FET
    FET #2 | 3.31.20 | Opted to cancelled due to pandemic, continued diet and tried naturally over the summer
    2nd Opinion with another RE | 8.20.20 | Not immune to measles (received 1 dose); SA results similar to 2 years ago; decided to move forward with FET #2 redo at start of next cycle
    Surprise natural BFP! | 9.22.20 | MC 10.23.20 at 8 weeks
    TTCAL naturally | starting 11.22.20

    Initial consultation with Reproductive Immunologist | 9.14.21
    Decidualization score biopsy | 10.1.21 | abnormal - low score of 1; endometrial scratch recommended and progesterone supplementation
    Saline sono | 10.15.21 | normal
    Bloodwork | 10.21.21 high TSH, high testosterone, positive for anti-nuclear antibodies and histone antibodies, high protein S, multiple genetic mutations
    BFP! | 11.3.21 | EDD 7.14.22 B) | biopsy provided same effect as endometrial scratch; added supplemental progesterone and estrogen, prednisone, levothyroxine, and MTX Support to maintain pregnancy
    DS born 7.19.22 after induction


    TTC #2 begins 6.2023
    Consultation with RI | 6.6.23
    Saline sono, endometritis biopsy, skin & eye check | all normal
    Labs | high TSH, Factor XIII mutation, high %CD56
    Follow up | 8.8.23 | prescribed metformin, prednisone, plaquenil, and levothyroxine
    Repeat labs after 3 weeks on meds
    Follow up | 11.9.23 | Green light!, increase in prednisone, added lovenox
    Repeat labs in 8 weeks
    Follow up | 1.16.24 | Green light continues
    TTC put on pause
  • edited October 2021
    @inthewoods23 spoilering because I'm wandering pretty far afield here and also some refs to the existence of abortion which... I suppose could be a TW sort of thing, i dunno.
    I'm going to stick to Islam here because my knowledge about Christian traditions is sketch, but within Islamic traditions, here's my understanding (I speak here as a non-Muslim scholar of the Muslim world): the fetus is considered to be endowed with a soul at 120 days of gestation. Prior to that point, the majority of Islamic scholars seem to feel that abortion is broadly permissible. Past that point, if the mother's health is at risk, abortion often remains an option, but it depends on the school of thought and the individual who is making the legal opinion. To be clear, the Quran and Hadith do not specifically discuss intentional abortion; this is a reading that is interperetively derived from other contexts. The reason abortion is relevant here is that, as I understand it, one of the religious objections one could make to IVF would be the formation of "excess" embryos that would be destroyed in the process (I guess, in some views, akin to abortion). So we can tick that concern off the list with Islam, since embryos are a long ways away from the 120-day point of becoming endowed with a soul. Muslim scholars also seem to be ok with things like cryo-preservation. The primary concern within an Islamic framework is the preservation of the marriage contract, which (with some exceptions not relevant to us here) restrict sexual contact outside of the marriage and, along with it, reproduction outside the marriage. Hence, it seems that embryos created during a marriage that subsequently breaks up, or if either partner in the marriage dies, cannot "legally" be used later and must be destroyed.
    Islamic belief when it comes to medical interventions are typically quite open-minded, seeing science as part and parcel of the scholarship that humans are enjoined to pursue. There are, of course, exceptions, but it does not follow the same kinds of rules that, say, particularly orthodox or also unusual readings of Christian doctrine might do (Jehovah's Witnesses, etc.).
    And FWIW everything I just said here is only relevant for the "mainstream" of Muslim opinion. There will be radicals in every tradition who believe all kinds of 😬🙄🙃 stuff.
    History
    I am doing this on my own. Left ovary and fallopian tube removed due to cyst/necrosis just after birth. Right ovary and tube still purport to function.
    Began TTC in Aug '18 @ age 35
    5 or 6 (or 7?!) cycles using frozen donor sperm, ICI. All BFN
    Mar-Jun '19 IUIs, all BFN
    Began process of referral for RE in spring of '19, blood tests confirm low AMH (.54) but all else is good.
    May '19 HSG shows open tube, but ultrasound suggests fibroids
    MRI in June '19 confirms two large fibroids, one growing through wall of uterus
    In June '19 I move from California to Oregon, disrupting my insurance, referrals, etc. 5 months spent piecing it all back together.
    Nov. '19 attempted myomectomy (vaginal approach) failed. 2nd surgery using laparoscopic method in Jan '20 is successful.
    April '20 --> June '20, natural IUIs, all BFN.
    July? saline ultrasound and bubble test demonstrate open tube
    July '20 clomid cycle cancelled for thin lining
    Aug-Oct, 3 femara cycles, all BFN
    RE referral. While waiting to set up an appointment Nov-Jan,I continue with natural cycles and ICI, using a known donor, BFN...
    Jan '21 more bloodwork, AMH is worse (.30), FSH high albeit not catastrophic at 13.2. hysteroscopy all good. "looks cozy!" says the RE.
    Feb '21, injectables (menopur, novarel), iui, BFN (doc said the frozen donor sperm sample had the "best numbers she'd ever seen!")
    Mar '21, injectables, iui cancelled due to lack of follicles, converted to at home-insem. BFN
    May '21, first IVF round cancelled due to cyst.
    July '21 IVF: standard antagonist. 225menupur/225gonal-f/cetrotide/5000u trigger, AFC 7; 6 days of stims. 8 eggs retrieved, 7 mature, 5 fertilize, 4 made it to blast. 3 are 4AB, 1 is 4BB. PGT-A results all abnormal.
    Oct '21 somewhat improved AMH (.51) and significantly improved FSH (8.9). Maybe it's all the pills I swallow.
    Dec -21, standard antagonist. 225menupur/225gonal-f/cetrotide/5000u trigger, AFC 5; 11 days of stims. retrieval yields 5, 4M, 2 reach day-6 blast (4AB & 4BB). 1 low-level mosaic (chr. 3 deletion), 1 complex abnormal.
    Feb '22 FET (low-level mosaic): CP.
    May '22 egg retrieval, lupron flare protocol. HGH priming for 1 month before stims; md lupron 20/20u daily; menopur 225, follistim 225, 10k trigger after 8 days of stims; AFC 10; 13 retrieved; 10 mature; 8 fertilized. All frozen at 2PN for later thaw, grow, and biopsy.
    July '22 egg retrieval same protocol: 9 days of stims; AFC 8; 10 retrieved, 8 mature, 4 fertilized and frozen.
    Sept '22 ER same protocol: AFC 10; 12 retrieved, 11 mature, 11 fertilized.
    From the 3 retrievals, 7 survived to day 5-6 blastocyst, from which I have 2 normal embryos!
    Jan 20, Fully medicated FET, baby aspirin, dexamethasone, acupuncture, and as much woo as I can stand (which isn't very much). BFN.
    July 23, Natural FET + baby aspirin. BFN.
  • @inthewoods23 I’m a “recovering Catholic” as they say. I was raised catholic but am not religious at all any more. The catholic objection to IVF is that they believe life begins at the moment of fertilization. So potentially disposing of fertilized embryos would be considered an abortion. 
  • @optimistgardener it amazes me how different these viewpoints are between religions. 120 days is a far cry from the life begins at conception belief.

    @gingermama29 yep that sounds familiar
    *TW* History:
    Me: 34 DH: 36 | Together since 2007 | Married July 2016

    TTC #1 since 7.2017
    Dx: low morph (1%), ANA positive, low decidualization score, high TSH and testosterone, histone antibodies

    IUI #1-3 all BFN
    IVF #1 | 6.11.19 | 24R, 17M, 15F, 6B, PGT-A tested - 5 normal, 3 girls & 2 boys
    FET #1 | 9.10.19 | BFN "I know you, but we've never met. I'm with you, but I don't know your name"
    RPL, Receptiva, & ERA testing | all normal/negative, recommended going on gluten and dairy free diet for next FET
    FET #2 | 3.31.20 | Opted to cancelled due to pandemic, continued diet and tried naturally over the summer
    2nd Opinion with another RE | 8.20.20 | Not immune to measles (received 1 dose); SA results similar to 2 years ago; decided to move forward with FET #2 redo at start of next cycle
    Surprise natural BFP! | 9.22.20 | MC 10.23.20 at 8 weeks
    TTCAL naturally | starting 11.22.20

    Initial consultation with Reproductive Immunologist | 9.14.21
    Decidualization score biopsy | 10.1.21 | abnormal - low score of 1; endometrial scratch recommended and progesterone supplementation
    Saline sono | 10.15.21 | normal
    Bloodwork | 10.21.21 high TSH, high testosterone, positive for anti-nuclear antibodies and histone antibodies, high protein S, multiple genetic mutations
    BFP! | 11.3.21 | EDD 7.14.22 B) | biopsy provided same effect as endometrial scratch; added supplemental progesterone and estrogen, prednisone, levothyroxine, and MTX Support to maintain pregnancy
    DS born 7.19.22 after induction


    TTC #2 begins 6.2023
    Consultation with RI | 6.6.23
    Saline sono, endometritis biopsy, skin & eye check | all normal
    Labs | high TSH, Factor XIII mutation, high %CD56
    Follow up | 8.8.23 | prescribed metformin, prednisone, plaquenil, and levothyroxine
    Repeat labs after 3 weeks on meds
    Follow up | 11.9.23 | Green light!, increase in prednisone, added lovenox
    Repeat labs in 8 weeks
    Follow up | 1.16.24 | Green light continues
    TTC put on pause
  • FWIW, in Judaism, a fetus is not a separate person until it takes its first breath. 
    TTC History
    TTC #1 Sep 2017-Sep 2018 
    BFP 11/30/2017 | MMC 12/31/2017
    BFP 6/22/2018 | CP 6/27/2018
    BFP 10/5/2018 | EDD 6/14/2019
    Baby girl born 6/19/19

    TTC #2 May 2020-November 2021
    BFP 7/18/2020 | MonoDi Twins | MMC 9/10/2020
    BFP 11/7/2020 | CP 11/9/2020
    RE Consult January 2021 | Dx "borderline DOR"/RPL
    IVF with PGT:
    Standard Antagonist:
    ER #1 3/27/2021 7R | 5M | 3F | 2B | 1 PGT-A Normal, 1 low-level mosaic
    ER #2 4/22/2021 10R | 7M | 3F | 2B | 0 normal, 2 aneuploid
    ER #3 5/19/2021 2R | 1M | 0F
    Estrogen Priming Antagonist:
    ER #4 7/10/2021 5R | 4M | 3F | 1B | 1 PGT-A Normal
    Duostim  (Standard Antagonist):
    ER #5 9/22/2021 13R | 11M | 8F | 5B | 2 PGT-A Normal, 1 low-level mosaic, 2 aneuploid
    ER #6 10/9/2021  9R | 6M | 4 F | 1B | 1 aneuploid
    FET #1  11/5/2021 | EDD 7/24/2022
    Baby boy born 7/19/22

    TTC #3 since May 2023 (ntnp)
    IVF Started Fall 2023 (Standard Antagonist)
    ER #7 10/6/2023 | 9R | 6M | 5F | 3B | 2 aneuploid, 1 high-level mosaic
    ER #8 10/31/2023 | 5R | 4M | 3F | 1B | 1 PGT-A Normal
    FET #2 11/27/23 | CP (bHCG = 8)
    FET #3 planned Jan 2024



  • FWIW, here's that article I read: https://www.washingtonpost.com/graphics/2018/national/how-religion-is-coming-to-terms-with-modern-fertility-methods/

    Also, I'm pretty sure I got Godsmacked: I lost my cross this morning, after posting this last night. Now, I kind of set myself up for that loss... I took off my cross for my massage on Sunday and put it into an unsecured pocket in my handbag.... and I sometimes don't zip up my handbag. So yeah... I was asking for it, but the timing is quite ironic. 
    MY CHART
    TTC History
    TTC#2
    Me: 40.5; MH: 39 | Met 02/2009 | Started Dating 08/2017 | Married 02/02/2020
    TTC #2 ... preparing as of March 2024


    TTC #1
    Me: 36, MH: 34 | Met 02/2009 | Started Dating 08/2017 | Married 02/02/2020
    TTC #1 02/2020 - 07/2022
    2009 | Dx PCOS; likely a misdiagnosis
    07/14/20 | Dx Hashimoto's Thyroditis
    07/21/20 | 1st RE appointment
    07/2120 - 08/20/20 | so much testing; no signs of PCOS
    08/20/20 | Dx Unexplained; AMA
    09/08/20 | IUI #1 Clomid + Trigger + Prometrium | BFN
    09/30/20 | Urology consult; more testing required
    10/2020 | Clomid + OPK + TI + Prometrium | BFN
    10/26/2020 | Starting 2nd IUI cycle, with Letrazole and with a new RE / different clinic
    11/03/2020 | New Dx "poor egg quality"; IUI cancelled in favor of Trigger + TI + Prometrium | BFN
    11/26/2020 | Combo IUI (Clomid + Menopur) + Trigger + Prometrium | BFN
    12/20/2020 | Combo IUI (Clomid + Gonal-F) + Trigger | IUI Cancelled due to thin lining; TI only | BFN
    01/14/2021 | Combo IUI (Letrazole + Menopur) + Trigger | BFN
    02/06/2021 | Switched to a new RE (TEW) ; trying naturally until we complete additional testing 
    03/14/2021 | Hybrid Double IUI, with Zymot (Letrazole, Gonal-F) + Trigger + Endometrin | Ovulated 4 mature eggs but still a BFN ☹️
    04/07/2021 | Natural cycle while we regroup | BFN
    04/09/2021 | Employer announces fertility benefits starting 05/01/2021! | Search for a new doctor who accepts insurance
    05/10/2021 | New RE consult & plan for IVF
    05/13/2021 | Mid-luteal IVF cycle #1 interrupted; had to get cancer genetic screening done to make sure I didn't have the same SDHA gene mutation as MH. 
    06/10/2021 | Aygestin priming IVF cycle #1; opted to Cx after 9 days of stims since only 5-6/12 follicles responded
    07/26/2021 | Attempt #2 at IVF cycle #1 (mid-luteal start): 8 retrieved, 8 MII, 6 fert (1 PN3), 3 Day 5 & 6 blasts: 3AA, 3AA, 6AB; 3 euploid
    08/09/2021 | Rest cycle / unmedicated TTC | Shockingly, a BFP! EDD: 5/25/202 | CP at 4w4d
    09/23/2021 | IVF cycle #2 (mid-luteal start): 14 retrieved, 13 MII, 11 fert, 5 Day 5 & 6 blasts: 2 x 3AA, 2 x 3AB, 3BB; 2 euploid
    11/12/2021 | IVF cycle #3 (mid-luteal start): cancelled due to ovaries being on vacation
    12/20/2021 | Rest cycle / unmedicated TTC + Pregmune Immunology Testing; BFN
    01/22/2022 | Rest cycle / unmedicated TTC + understanding uncovered immunological issues; BFN
    02/18/2022 | Mock transfer cycle! ERA, ReceptivaDx, EMMA/ALICE; start Prednisone to address NK activity
    03/16/2022 | Final, "Hail Mary" super-ovulation + TI cycle before FET; BFP! EDD: 12/21/2022 | MMC 05/08/2022
    05/20/2022 | D&C; recovering... 
    06/21/2022 | Trying naturally until October 2022
    07/21/2022 | BFP! EDD 04/02/2023; 👦🏼 born on 4/5/2023


  • @acleverusername i realize i haven't commented on your great update on the stim situation so far! i think i'm just having a hard time believing you're already doing another round so soon. crazy! I really hope they're able to "catch" all those middle-of-the-pack follicles. Thanks also for sharing the TEW interview. I listened to it this morning. I hope you're making sure to take care of yourself and take some breaks. It sounds like there's a lot going on in your life right now. I see the telltale signs of little stuff going haywire: the missing cross, the Ganirelix being left out overnight... that are all things that start happening to me when I'm not giving myself enough time off. Especially now that you're growing a big crop of follicles: make sure you rest!!
    History
    I am doing this on my own. Left ovary and fallopian tube removed due to cyst/necrosis just after birth. Right ovary and tube still purport to function.
    Began TTC in Aug '18 @ age 35
    5 or 6 (or 7?!) cycles using frozen donor sperm, ICI. All BFN
    Mar-Jun '19 IUIs, all BFN
    Began process of referral for RE in spring of '19, blood tests confirm low AMH (.54) but all else is good.
    May '19 HSG shows open tube, but ultrasound suggests fibroids
    MRI in June '19 confirms two large fibroids, one growing through wall of uterus
    In June '19 I move from California to Oregon, disrupting my insurance, referrals, etc. 5 months spent piecing it all back together.
    Nov. '19 attempted myomectomy (vaginal approach) failed. 2nd surgery using laparoscopic method in Jan '20 is successful.
    April '20 --> June '20, natural IUIs, all BFN.
    July? saline ultrasound and bubble test demonstrate open tube
    July '20 clomid cycle cancelled for thin lining
    Aug-Oct, 3 femara cycles, all BFN
    RE referral. While waiting to set up an appointment Nov-Jan,I continue with natural cycles and ICI, using a known donor, BFN...
    Jan '21 more bloodwork, AMH is worse (.30), FSH high albeit not catastrophic at 13.2. hysteroscopy all good. "looks cozy!" says the RE.
    Feb '21, injectables (menopur, novarel), iui, BFN (doc said the frozen donor sperm sample had the "best numbers she'd ever seen!")
    Mar '21, injectables, iui cancelled due to lack of follicles, converted to at home-insem. BFN
    May '21, first IVF round cancelled due to cyst.
    July '21 IVF: standard antagonist. 225menupur/225gonal-f/cetrotide/5000u trigger, AFC 7; 6 days of stims. 8 eggs retrieved, 7 mature, 5 fertilize, 4 made it to blast. 3 are 4AB, 1 is 4BB. PGT-A results all abnormal.
    Oct '21 somewhat improved AMH (.51) and significantly improved FSH (8.9). Maybe it's all the pills I swallow.
    Dec -21, standard antagonist. 225menupur/225gonal-f/cetrotide/5000u trigger, AFC 5; 11 days of stims. retrieval yields 5, 4M, 2 reach day-6 blast (4AB & 4BB). 1 low-level mosaic (chr. 3 deletion), 1 complex abnormal.
    Feb '22 FET (low-level mosaic): CP.
    May '22 egg retrieval, lupron flare protocol. HGH priming for 1 month before stims; md lupron 20/20u daily; menopur 225, follistim 225, 10k trigger after 8 days of stims; AFC 10; 13 retrieved; 10 mature; 8 fertilized. All frozen at 2PN for later thaw, grow, and biopsy.
    July '22 egg retrieval same protocol: 9 days of stims; AFC 8; 10 retrieved, 8 mature, 4 fertilized and frozen.
    Sept '22 ER same protocol: AFC 10; 12 retrieved, 11 mature, 11 fertilized.
    From the 3 retrievals, 7 survived to day 5-6 blastocyst, from which I have 2 normal embryos!
    Jan 20, Fully medicated FET, baby aspirin, dexamethasone, acupuncture, and as much woo as I can stand (which isn't very much). BFN.
    July 23, Natural FET + baby aspirin. BFN.
  • @zwink1 good luck with your transfer tomorrow!!! I can’t believe the day is finally here! All the clinic switching and document transfer and PIO shots and *blink* you’re here!
    MY CHART
    TTC History
    TTC#2
    Me: 40.5; MH: 39 | Met 02/2009 | Started Dating 08/2017 | Married 02/02/2020
    TTC #2 ... preparing as of March 2024


    TTC #1
    Me: 36, MH: 34 | Met 02/2009 | Started Dating 08/2017 | Married 02/02/2020
    TTC #1 02/2020 - 07/2022
    2009 | Dx PCOS; likely a misdiagnosis
    07/14/20 | Dx Hashimoto's Thyroditis
    07/21/20 | 1st RE appointment
    07/2120 - 08/20/20 | so much testing; no signs of PCOS
    08/20/20 | Dx Unexplained; AMA
    09/08/20 | IUI #1 Clomid + Trigger + Prometrium | BFN
    09/30/20 | Urology consult; more testing required
    10/2020 | Clomid + OPK + TI + Prometrium | BFN
    10/26/2020 | Starting 2nd IUI cycle, with Letrazole and with a new RE / different clinic
    11/03/2020 | New Dx "poor egg quality"; IUI cancelled in favor of Trigger + TI + Prometrium | BFN
    11/26/2020 | Combo IUI (Clomid + Menopur) + Trigger + Prometrium | BFN
    12/20/2020 | Combo IUI (Clomid + Gonal-F) + Trigger | IUI Cancelled due to thin lining; TI only | BFN
    01/14/2021 | Combo IUI (Letrazole + Menopur) + Trigger | BFN
    02/06/2021 | Switched to a new RE (TEW) ; trying naturally until we complete additional testing 
    03/14/2021 | Hybrid Double IUI, with Zymot (Letrazole, Gonal-F) + Trigger + Endometrin | Ovulated 4 mature eggs but still a BFN ☹️
    04/07/2021 | Natural cycle while we regroup | BFN
    04/09/2021 | Employer announces fertility benefits starting 05/01/2021! | Search for a new doctor who accepts insurance
    05/10/2021 | New RE consult & plan for IVF
    05/13/2021 | Mid-luteal IVF cycle #1 interrupted; had to get cancer genetic screening done to make sure I didn't have the same SDHA gene mutation as MH. 
    06/10/2021 | Aygestin priming IVF cycle #1; opted to Cx after 9 days of stims since only 5-6/12 follicles responded
    07/26/2021 | Attempt #2 at IVF cycle #1 (mid-luteal start): 8 retrieved, 8 MII, 6 fert (1 PN3), 3 Day 5 & 6 blasts: 3AA, 3AA, 6AB; 3 euploid
    08/09/2021 | Rest cycle / unmedicated TTC | Shockingly, a BFP! EDD: 5/25/202 | CP at 4w4d
    09/23/2021 | IVF cycle #2 (mid-luteal start): 14 retrieved, 13 MII, 11 fert, 5 Day 5 & 6 blasts: 2 x 3AA, 2 x 3AB, 3BB; 2 euploid
    11/12/2021 | IVF cycle #3 (mid-luteal start): cancelled due to ovaries being on vacation
    12/20/2021 | Rest cycle / unmedicated TTC + Pregmune Immunology Testing; BFN
    01/22/2022 | Rest cycle / unmedicated TTC + understanding uncovered immunological issues; BFN
    02/18/2022 | Mock transfer cycle! ERA, ReceptivaDx, EMMA/ALICE; start Prednisone to address NK activity
    03/16/2022 | Final, "Hail Mary" super-ovulation + TI cycle before FET; BFP! EDD: 12/21/2022 | MMC 05/08/2022
    05/20/2022 | D&C; recovering... 
    06/21/2022 | Trying naturally until October 2022
    07/21/2022 | BFP! EDD 04/02/2023; 👦🏼 born on 4/5/2023


  • @zwink1 good luck today!!!!
    TTC History
    Me: 35 DH: 34
    Married 07/2012
    DD born 07/2014
    DD2 born 10/2018
    DS born 10/2022

    IF history:
    TTC #2 since January 2016
    June-Aug 2017: 3 IUIs w/Clomid = BFN
    Sept 2017: Dx w/Endometriosis
    Oct 2017: IUI w/Letrozole = BFN
    Nov 2017: IUI w/Letrozole = BFN
    Dec 2017: pre-IVF testing
    Jan-Feb 2018: IVF--17 eggs retrieved, 13 fertilized, 9 frozen and 1 transferred on 2/10 = BFP on 2/19!!! EDD 10/29/2018
    FET Oct 2021: BFP on 10/31! MC at 5 weeks
    FET Feb 2022: BFP on 2/15! EDD 10/29/22


  • good luck @zwink1!
    History
    I am doing this on my own. Left ovary and fallopian tube removed due to cyst/necrosis just after birth. Right ovary and tube still purport to function.
    Began TTC in Aug '18 @ age 35
    5 or 6 (or 7?!) cycles using frozen donor sperm, ICI. All BFN
    Mar-Jun '19 IUIs, all BFN
    Began process of referral for RE in spring of '19, blood tests confirm low AMH (.54) but all else is good.
    May '19 HSG shows open tube, but ultrasound suggests fibroids
    MRI in June '19 confirms two large fibroids, one growing through wall of uterus
    In June '19 I move from California to Oregon, disrupting my insurance, referrals, etc. 5 months spent piecing it all back together.
    Nov. '19 attempted myomectomy (vaginal approach) failed. 2nd surgery using laparoscopic method in Jan '20 is successful.
    April '20 --> June '20, natural IUIs, all BFN.
    July? saline ultrasound and bubble test demonstrate open tube
    July '20 clomid cycle cancelled for thin lining
    Aug-Oct, 3 femara cycles, all BFN
    RE referral. While waiting to set up an appointment Nov-Jan,I continue with natural cycles and ICI, using a known donor, BFN...
    Jan '21 more bloodwork, AMH is worse (.30), FSH high albeit not catastrophic at 13.2. hysteroscopy all good. "looks cozy!" says the RE.
    Feb '21, injectables (menopur, novarel), iui, BFN (doc said the frozen donor sperm sample had the "best numbers she'd ever seen!")
    Mar '21, injectables, iui cancelled due to lack of follicles, converted to at home-insem. BFN
    May '21, first IVF round cancelled due to cyst.
    July '21 IVF: standard antagonist. 225menupur/225gonal-f/cetrotide/5000u trigger, AFC 7; 6 days of stims. 8 eggs retrieved, 7 mature, 5 fertilize, 4 made it to blast. 3 are 4AB, 1 is 4BB. PGT-A results all abnormal.
    Oct '21 somewhat improved AMH (.51) and significantly improved FSH (8.9). Maybe it's all the pills I swallow.
    Dec -21, standard antagonist. 225menupur/225gonal-f/cetrotide/5000u trigger, AFC 5; 11 days of stims. retrieval yields 5, 4M, 2 reach day-6 blast (4AB & 4BB). 1 low-level mosaic (chr. 3 deletion), 1 complex abnormal.
    Feb '22 FET (low-level mosaic): CP.
    May '22 egg retrieval, lupron flare protocol. HGH priming for 1 month before stims; md lupron 20/20u daily; menopur 225, follistim 225, 10k trigger after 8 days of stims; AFC 10; 13 retrieved; 10 mature; 8 fertilized. All frozen at 2PN for later thaw, grow, and biopsy.
    July '22 egg retrieval same protocol: 9 days of stims; AFC 8; 10 retrieved, 8 mature, 4 fertilized and frozen.
    Sept '22 ER same protocol: AFC 10; 12 retrieved, 11 mature, 11 fertilized.
    From the 3 retrievals, 7 survived to day 5-6 blastocyst, from which I have 2 normal embryos!
    Jan 20, Fully medicated FET, baby aspirin, dexamethasone, acupuncture, and as much woo as I can stand (which isn't very much). BFN.
    July 23, Natural FET + baby aspirin. BFN.
Sign In or Register to comment.
Choose Another Board
Search Boards
"
"