JamieH2000 - Noooo! Do you know if you had any degree of this when you carried your son (can't remember if you did a biopsy before transferring for #1)? Like I'm wondering what if this is something you've had all along? Honestly depending on what your RE says today if I were you I might just give it a shot and transfer at this point, but keep in mind this is coming from someone with no experience in this department so I don't know the risks. Things I'd want to know (which I know you already intend to ask) are how severe the infection appears to be (however they measure that) and if there are any risks to a fetus or if it simply interferes with implantation but once that is achieved it's not an issue. Also if you get pregnant would the infection likely just remain as is or do these things tend to escalate and then what do you do (can you take antibiotics while pregnant?) Not sure how big your OB's practice is but I wonder if you could loop him/her in and get you OB's take on it re: risk of complications in pregnancy or to the baby if the transfer does work. Ugh, I'm sorry.
Thanks @c-town18 and @lmajin99! I did not have this with my first. I honestly think its more common with a second since alot of bacteria can get in the uterus during birth. almost everyone I have found to be dealing with this seems to be trying for a second or more.
I had a good convo with my RE. WE talked about so much. I wish I could remember it all. Basically, we have tried all 5 classes of antibiotics, so i really shouldn't have an infection anymore. We have cleaned out the inflammation tissue, and then biopsy she sent was a polyp, so of course it came as as endometritis. She is hopeful the uterus is ready to go. She wonders if the inflammation is maybe an immune thing and not an infection? Her plan would be to transfer and add in doxycycline and a steroid during the cycle to help with anymore possible infection or inflammation. She is also doing some more research since there was some allergic reaction found in my biopsy too? SHe put my case up for review this week with the 10 other physicians in the practice. Honestly, I think we are doing everything we can. I'm very nervous to transfer though. I read too much on the internet how unresolved endometritis can hurt implantation and increase miscarriage. but I also know the longer we wait, the more likely polyps or scar tissue would come back and we would need another hysterscopy. So if none of the other doctors have any big insights, i think we will probably try to transfer in Nov. If it doesn't work, I guess its back to biopsies and more meds. Ugh. She made me feel more hopeful in that she has a handful of patients dealing with this at any given time, and she said most go on to be successful. She was confident i would have success in the end. So I'm just gonna try to trust her plan once we finalize that.
History in Spoiler
Age: 32 (same with DH). Together since 2006, Married June 2013 and TTC since August 2015 Diagnosis: Mild Endo, DOR (AMH of 1.5), Poor Quality Eggs/embryos, Displaced Window of Implantation (ERA Post Receptive) March-May 2016: 1 TI and 2 IUIs- BFN June 2016- Laproscopy- found/removed mild endo and confirmed only 1 normal healthy ovary. August 2016- IVF #1 with Antagonist Protocol- Cancelled (2 lead follies), converted to IUI- BFN Oct-Nov 2016- IVF #2 with Estrogen Priming Micro Lupron Protocol, 2 eggs retrieved, day 3 transfer of 1- BFN January 2017- New RE, IVF#3 with Estrogen Priming Antagonist Protocol, 12 eggs, 8 mature, 6 fertilized, 2 day 5 early blasts transferred (none to freeze ), BFN May 2017- Sept 2017- Starting Donor Egg process! Waiting for donor to be available... and then she is pregnant at baseline Oct 2017- Donor #2: 25R, 22M,18F, 12 blasts frozen! Fresh transfer cancelled due to thin lining with fluid Nov 2017- Hysterscopy to remove polyp Dec 2017- DE FET #1 on 12/8 on 2 perfect blasts- BFN and devastated Jan-Mar 2018- ERA #1- Post receptive by 24 hours, ERA #2 RECEPTIVE with 4 days of Progesterone Apr 2018- DE FET cancelled for lining issues Jun 2018- DE FET #2 of two 1AA blasts- first BFP ever! Beta 10dp5dt- 378, Beta 14dp5dt- 2840, Beta 16dp5dt- 4035, beta 18dp5dt- 10916. Due on 2/20 with one baby after a vanishing twin Baby Born born early @ 33.5 weeks due to Pre-e Back for # 2!
@JamieH2000 WTF. I don't even know what else to say. I saw your post on FB and was so sad for you - @lucyb1954 so fun to see your face - Hopefully your RE will have some answers for you but seriously, WTF.
Thanks for the well wishes everyone. I'm feeling cautiously hopeful. I don't remember if I've shared this particular crazy thought but I have an embryo (4AB) that I assumed they were going to transfer last time but instead they transferred the 4BA. It doesn't really matter which one they put in but for some reason it confused me and it just felt 'wrong'. So, know I'm convinced that the 4AB is the one that is meant to be and won't that be a cool story if this is successful and if it's not successful whatever - it can't suck more than the other 3 failures. Right?
Will I test? That's a great question. We leave early next Wednesday which is 6dp5dt and when I would normally start testing. I would love to say I'm going to wait but I have literally never, not once in 4 transfers, been able to wait. I think with my first transfer I was able to hold out to 7dp5dt (fresh transfer). Maybe I'll try and wait until the morning after we get there (7days) and if it's negative I'll let myself have a glass of wine. Maybe I'll be too distracted and be able to hold out but I doubt it.
History and blog link in spoiler
2016 - dx with super low ovarian reserve; failed cycle with clomid, failed IUI, 2017 - egg retrieval #1 - 3 eggs, 0 embryos appropriate for transfer; ER #2 2 eggs, 0 embryos on day 3; ER #3 1 egg 0 embryos moved to donor egg in summer 2017; 35 eggs retrieved; 19 fertilized; 9 total embryos Fresh transfer Dec 2017= BFP! baby boy born 8/22/18
May 2019 - surprise natural pregnancy ended in MC Nov 2019 FET; MC at 9 weeks May 2020 FET; BFN July 2020 FET; CP treated with methotrexate Oct 2020 BFP!
laurad75 - I bet that 4AB IS the one! I'm totally on board with that story, makes sense to me.
JamieH2000 - If none of the other docs in your clinic have any further suggestions, and if your RE thinks it's a reasonable decision, I would totally transfer asap if I were you. You're battling a few different issues here between this and the polyps and the scar tissue and there may not ever be a time when everything is just right ya know? If you at least know the polyps and scar tissue are clear for the time being, I say jump on it. Ugh, I'm sorry you just can't catch a break here friend.
@laurad75 I'm excited for you tomorrow! All things crossed, and I'm happy you get to go on vacation afterwards. It would be so hard not to test. I don't really know how people do it! I'm super hopeful for you and it sounds good that you've got the right embryo this time around!
@JamieH2000 Ugh, so frustrating for you! It sounds good that your RE has experience with this and sees folks go on to have successful transfers. It is so hard to know what to do in this situation but it does sound like if she sent the polyp for testing, of course it's going to come back as inflamed. I know it sucks, but would testing any of the regular endometrial tissue give you a potentially different answer? I know that some REs have steroids as part of their transfer protocols, particularly for folks with autoimmune issues, so perhaps that could be very useful for you. It's so crazy that you could have this kind of thing and it's so hard to get rid of and you wouldn't even really know you had it except for a failed transfer. I'm interested to hear what the panel says about transfer...does your clinic keep any in house stats on that kind of thing? Anyway, I'm really rooting for you Keep us posted!
@laurad75- I love your good feeling on the transfer. and your attitude. I need to try to remember that a failure is not the end of the road. and try to not get my hopes up so much again (tho I tried to think that way last time and failed). Its so hard when you know that baby is inside and they just need to stick! Aww, testing or not is SUCH a hard decision. I guess i would personally try to not.. but then again, its its negative, some wine in the smokies would be a nice thing given the dissapointment. Will be thinking of you SOO Much!!
@c-town18- my thoughts exactly. I'm interested in what the other REs will say. it will throw me for a bit of a loop if enough say not to transfer and my RE changes her mind. So kinda just waiting to hear until i get totally set on a transfer... though i am already kinda thinking in transfer mode (time to cut out diet soda, extra sugar, alcohol, etc- whatever i can do to lower inflammation, though i don't really beleive all of that makes much difference, but it can't hurt).
@lucyb1954- thanks friend!! i really wish she had tested a normal tissue to see if the inflammation cells were there. THough if they were, I'm not sure what we would do since we have done all the antibiotics. My transfer protocol has always had a steroid and antibiotic (its "old school" she said last time, but it worked, so we were keeping with it). So now we will do two antibiotics. I just hope if somehow the embryo sticks, we aren't at higher risk of loss. Reading the studies and science on it really freaked me out. They all showed much better results with the endometritis resolved. and we don't know if its resolved. But the studies also showed that the meds (usually just one or two antibiotics) cleared this for like everyone. So it does make me wonder if the inflammation is from some odd immune response. SHe is also starting me on a new vaginal probiotic today, in case the other one had some ingredient in that i was allergic to since they found Eosonofils, which are white blood cells evidence of allergies apparently? My seasonal fall allergies have been the worst in years this year, but not sure how my uterus would be showing that?!
History in Spoiler
Age: 32 (same with DH). Together since 2006, Married June 2013 and TTC since August 2015 Diagnosis: Mild Endo, DOR (AMH of 1.5), Poor Quality Eggs/embryos, Displaced Window of Implantation (ERA Post Receptive) March-May 2016: 1 TI and 2 IUIs- BFN June 2016- Laproscopy- found/removed mild endo and confirmed only 1 normal healthy ovary. August 2016- IVF #1 with Antagonist Protocol- Cancelled (2 lead follies), converted to IUI- BFN Oct-Nov 2016- IVF #2 with Estrogen Priming Micro Lupron Protocol, 2 eggs retrieved, day 3 transfer of 1- BFN January 2017- New RE, IVF#3 with Estrogen Priming Antagonist Protocol, 12 eggs, 8 mature, 6 fertilized, 2 day 5 early blasts transferred (none to freeze ), BFN May 2017- Sept 2017- Starting Donor Egg process! Waiting for donor to be available... and then she is pregnant at baseline Oct 2017- Donor #2: 25R, 22M,18F, 12 blasts frozen! Fresh transfer cancelled due to thin lining with fluid Nov 2017- Hysterscopy to remove polyp Dec 2017- DE FET #1 on 12/8 on 2 perfect blasts- BFN and devastated Jan-Mar 2018- ERA #1- Post receptive by 24 hours, ERA #2 RECEPTIVE with 4 days of Progesterone Apr 2018- DE FET cancelled for lining issues Jun 2018- DE FET #2 of two 1AA blasts- first BFP ever! Beta 10dp5dt- 378, Beta 14dp5dt- 2840, Beta 16dp5dt- 4035, beta 18dp5dt- 10916. Due on 2/20 with one baby after a vanishing twin Baby Born born early @ 33.5 weeks due to Pre-e Back for # 2!
Me: 45yo, DH: 47yo 3 Daughters (singleton @27yo, ID Di/Di Twins @34yo) Protein S Deficiency (Blood Clotting Disorder), MTHFR & VIT D issue 5 MC's: Blighted Ovum-D&C @ 9wks; Natural MC @ 7wks; Blighted Ovum-D&C @ 9wks; MC boy-D&C @ 9wks & Chem PG in 2019 Tubes were tied after my Twins (and now I am old). Remarried and want to give my DH a baby!
IVF#1 OE June 2019 - ER 6/15/19, 24R, 21M, 20F, 7 6DBlasts Frozen for PGS Testing, RESULTS of PGS 4 abnormal girls, 2 abnormal boys, 1 indeterminate girl FET#1 OE August 23, 2019 (transferring 1 indeterminate girl & 1 abnormal boy) - BFN IVF#2 November 15, 2019 - ER 9R, 9M, 6F, 2 5dBlasts (fresh transfer) and 1 6DBlast frozen for PGS Testing, FRESH Transfer: November 20, 2019, 2 5-day blasts transferred!! BFP 8dp5dt on 11/27 - 12/2 on FRER, BETA #1 12/2 - 11.93. BETA #2 12/4: 4.41 ~CHEMICAL PG ******************Starting Donor Process June 2020: Egg Donor Cycle and Fresh Transfer of 1 embryo in Czech Republic - CANCELLED DUE TO COVID19 October 2020. Split Cycle at UFC with a friend (Andrea) I met on the Bump who was also supposed to go to Prague too DE Retrieval9/26/2020, 26R, 24M, 12 split Cycle, 9 Fertilized + 1 "questionable", PRAYING FOR AT LEAST 5 BLASTS 10/1/2020: 4 5DBlasts (AA, BB, BC, BC), 10/2/2020: 3 6DBlasts (BB, BB, BC) FOR A TOTAL OF: 7 BLASTS!! THANK YOU GOD!! PGS RESULTS: 5 NORMALS! DAY 5: AA BOY, BB GIRL, BC BOY / DAY 6: BB GIRL, BC GIRL DE FETOctober 29, 2020 - CANCELED DUE TO FLUID IN LINING DE FET November 16th, 2020 (transferring an PGS normal Hatching AA Boy)
@Laurad75- let us know how it goes!! No issues with your lining this cycle?! Hopefully they figured out how much estrogen you need after the last few this one has to be it!!
History in Spoiler
Age: 32 (same with DH). Together since 2006, Married June 2013 and TTC since August 2015 Diagnosis: Mild Endo, DOR (AMH of 1.5), Poor Quality Eggs/embryos, Displaced Window of Implantation (ERA Post Receptive) March-May 2016: 1 TI and 2 IUIs- BFN June 2016- Laproscopy- found/removed mild endo and confirmed only 1 normal healthy ovary. August 2016- IVF #1 with Antagonist Protocol- Cancelled (2 lead follies), converted to IUI- BFN Oct-Nov 2016- IVF #2 with Estrogen Priming Micro Lupron Protocol, 2 eggs retrieved, day 3 transfer of 1- BFN January 2017- New RE, IVF#3 with Estrogen Priming Antagonist Protocol, 12 eggs, 8 mature, 6 fertilized, 2 day 5 early blasts transferred (none to freeze ), BFN May 2017- Sept 2017- Starting Donor Egg process! Waiting for donor to be available... and then she is pregnant at baseline Oct 2017- Donor #2: 25R, 22M,18F, 12 blasts frozen! Fresh transfer cancelled due to thin lining with fluid Nov 2017- Hysterscopy to remove polyp Dec 2017- DE FET #1 on 12/8 on 2 perfect blasts- BFN and devastated Jan-Mar 2018- ERA #1- Post receptive by 24 hours, ERA #2 RECEPTIVE with 4 days of Progesterone Apr 2018- DE FET cancelled for lining issues Jun 2018- DE FET #2 of two 1AA blasts- first BFP ever! Beta 10dp5dt- 378, Beta 14dp5dt- 2840, Beta 16dp5dt- 4035, beta 18dp5dt- 10916. Due on 2/20 with one baby after a vanishing twin Baby Born born early @ 33.5 weeks due to Pre-e Back for # 2!
Thanks Ladies! I’m home chilling out after a smooth transfer. They put in the 4AB and I almost cried when I saw the photo. As always, I thought I was going to die from a bladder explosion. I must have the world’s smallest bladder. It fills in no time and then I want to cry until I can pee again.
History and blog link in spoiler
2016 - dx with super low ovarian reserve; failed cycle with clomid, failed IUI, 2017 - egg retrieval #1 - 3 eggs, 0 embryos appropriate for transfer; ER #2 2 eggs, 0 embryos on day 3; ER #3 1 egg 0 embryos moved to donor egg in summer 2017; 35 eggs retrieved; 19 fertilized; 9 total embryos Fresh transfer Dec 2017= BFP! baby boy born 8/22/18
May 2019 - surprise natural pregnancy ended in MC Nov 2019 FET; MC at 9 weeks May 2020 FET; BFN July 2020 FET; CP treated with methotrexate Oct 2020 BFP!
@laurad75- glad it was smooth- except the bladder part! I have learned to hardly drink water before. I have often had to let out some pee and it’s hard to only let out a little! Hope you are home relaxing now and taking it easy!!
AFM- finally some good news I guess? Sounds like the other docs agree we should move forward with the transfer. I got my calendar and so much on it!’ I take 3 types of estrogen and then lupron and then the antiobtiocs and steroid and of course PIo.. and aspirin too. Now I’m just hoping everything goes smoothly with my lining and transfer day is 4.5 weeks away!
History in Spoiler
Age: 32 (same with DH). Together since 2006, Married June 2013 and TTC since August 2015 Diagnosis: Mild Endo, DOR (AMH of 1.5), Poor Quality Eggs/embryos, Displaced Window of Implantation (ERA Post Receptive) March-May 2016: 1 TI and 2 IUIs- BFN June 2016- Laproscopy- found/removed mild endo and confirmed only 1 normal healthy ovary. August 2016- IVF #1 with Antagonist Protocol- Cancelled (2 lead follies), converted to IUI- BFN Oct-Nov 2016- IVF #2 with Estrogen Priming Micro Lupron Protocol, 2 eggs retrieved, day 3 transfer of 1- BFN January 2017- New RE, IVF#3 with Estrogen Priming Antagonist Protocol, 12 eggs, 8 mature, 6 fertilized, 2 day 5 early blasts transferred (none to freeze ), BFN May 2017- Sept 2017- Starting Donor Egg process! Waiting for donor to be available... and then she is pregnant at baseline Oct 2017- Donor #2: 25R, 22M,18F, 12 blasts frozen! Fresh transfer cancelled due to thin lining with fluid Nov 2017- Hysterscopy to remove polyp Dec 2017- DE FET #1 on 12/8 on 2 perfect blasts- BFN and devastated Jan-Mar 2018- ERA #1- Post receptive by 24 hours, ERA #2 RECEPTIVE with 4 days of Progesterone Apr 2018- DE FET cancelled for lining issues Jun 2018- DE FET #2 of two 1AA blasts- first BFP ever! Beta 10dp5dt- 378, Beta 14dp5dt- 2840, Beta 16dp5dt- 4035, beta 18dp5dt- 10916. Due on 2/20 with one baby after a vanishing twin Baby Born born early @ 33.5 weeks due to Pre-e Back for # 2!
@laurad75 lady!!!!! Crossing everything for you! So glad it was a smooth transfer! Hope the 2ww is uneventful and goes by quick:) stick little embaby!
@JamieH2000 good grief on the endometritis!!! FFS!!! Ugh I wish they had tested other tissue to check for inflammation too. You could do an anti inflammation diet if you wanted to, but as someone who tried it a few times, I know it’s very hard, and limiting. and it takes like 30 days so probably not something you are wanting to embark on. I’m glad your Doctor seems to be very hopeful still, and that the other doctors will also weigh in. I know you must be so frustrated. This is shit. Remind me, you still have some embryos that are untested? Or have you tested all already. I just remember you had an impressive amount but can’t remember when you did go back and test them if you tested them all.
@lucyb1954 hey lady! Am planning to respond to your DM ASAP!
Me: Hashimoto Autoimune Disease Homozygous MTHFR Cr677 DOR - AMH .27 High FSH (don't even know how high) 2 iui's to start - BFN IVF 1 -3 made it do day 5! 2 5AA 1 6BB PGS results = all abnormal IVF 2 - stimmed for 19 days. insanity. Had 5 follicles that looked mature but only 2 contained mature eggs the others were empty. Nothing made it to day 5 IVF 3 - added in HGH - 4 mature follicles (had some empties again) 3 made it to day 5/6 for PGS (held for testing with next retrieval IVF 4 - Upped my dosage for the first time - Canceled 11 days into sims - looked like 1 follicle and we were afraid it was empty IVF 5 - Canceled - looked like 1 follicle and we were afraid it was empty IVF 6 - 3 mature, 2 fertalized 1 made it to day 5 and sent for PGS
Sent in IVF round 3 and 6 (4 embryos) for PGS testing and got 2 normal embryos!!! 1Boy and 1Girl. Took a little over a year to get those two embryos so demanded all sorts of test prior to attempting transfer. Did EFT, ERA and NK Cells testing.
FET#1 - Intralipid drips, Prednisone, and did a depot lupron shot before starting the FET protocol Chemical pregnancy FET#2 - PGS normal boy - BFN Natural pregnancy - cycle following the FET2???? Miscarriage at 8 weeks. viability scan had shown an enlarged yolk sac so I had been warned that it was likely not chromosonally normal
DEIVF cycle - picked a donor who is willing to be open! Her cycle resulted in in 4 PGS Normal embryos 1st transfer - chemical pregnancy 2nd transfer - success, May 17 2020 due date!
@hopefuljj- we currently have 3 pgs normals left and 4 more untested. So that’s a huge huge blessing. If this doesn’t stick tho, I’m gonna be pretty concerned about my uterus since all these docs think it should be fixed now....
History in Spoiler
Age: 32 (same with DH). Together since 2006, Married June 2013 and TTC since August 2015 Diagnosis: Mild Endo, DOR (AMH of 1.5), Poor Quality Eggs/embryos, Displaced Window of Implantation (ERA Post Receptive) March-May 2016: 1 TI and 2 IUIs- BFN June 2016- Laproscopy- found/removed mild endo and confirmed only 1 normal healthy ovary. August 2016- IVF #1 with Antagonist Protocol- Cancelled (2 lead follies), converted to IUI- BFN Oct-Nov 2016- IVF #2 with Estrogen Priming Micro Lupron Protocol, 2 eggs retrieved, day 3 transfer of 1- BFN January 2017- New RE, IVF#3 with Estrogen Priming Antagonist Protocol, 12 eggs, 8 mature, 6 fertilized, 2 day 5 early blasts transferred (none to freeze ), BFN May 2017- Sept 2017- Starting Donor Egg process! Waiting for donor to be available... and then she is pregnant at baseline Oct 2017- Donor #2: 25R, 22M,18F, 12 blasts frozen! Fresh transfer cancelled due to thin lining with fluid Nov 2017- Hysterscopy to remove polyp Dec 2017- DE FET #1 on 12/8 on 2 perfect blasts- BFN and devastated Jan-Mar 2018- ERA #1- Post receptive by 24 hours, ERA #2 RECEPTIVE with 4 days of Progesterone Apr 2018- DE FET cancelled for lining issues Jun 2018- DE FET #2 of two 1AA blasts- first BFP ever! Beta 10dp5dt- 378, Beta 14dp5dt- 2840, Beta 16dp5dt- 4035, beta 18dp5dt- 10916. Due on 2/20 with one baby after a vanishing twin Baby Born born early @ 33.5 weeks due to Pre-e Back for # 2!
@JamieH2000 oh that’s amazing. And yes I totally hear you about the uterus concerns. I’ve had 3 PGS great graded embryos fail after an ERA, so it’s like which rabbit hole to go down, the uterus? Or immuno hole? It’s all so scary and I’m already in a hot hot panic that I only have 2 left and what if neither work?!!! So yeah, I get it 100%. Did the say anything more about the ashermans? I have a friend who got pregnant with it but had lining issues during all her FET’s but it all worked out! She’s trying for baby #2 now. There are so many conditions also where it just means it might take a couple transfers but will eventually work, cuz it depends where the embryo decides to settle. But it’s glad they got it all cleared out for now, let’s hope that embryo chooses a perfect part of your uterus to snuggle into when you get to transfer. You’ve got this lady! Channel the power of positive thinking if possible 😬🙃
Me: Hashimoto Autoimune Disease Homozygous MTHFR Cr677 DOR - AMH .27 High FSH (don't even know how high) 2 iui's to start - BFN IVF 1 -3 made it do day 5! 2 5AA 1 6BB PGS results = all abnormal IVF 2 - stimmed for 19 days. insanity. Had 5 follicles that looked mature but only 2 contained mature eggs the others were empty. Nothing made it to day 5 IVF 3 - added in HGH - 4 mature follicles (had some empties again) 3 made it to day 5/6 for PGS (held for testing with next retrieval IVF 4 - Upped my dosage for the first time - Canceled 11 days into sims - looked like 1 follicle and we were afraid it was empty IVF 5 - Canceled - looked like 1 follicle and we were afraid it was empty IVF 6 - 3 mature, 2 fertalized 1 made it to day 5 and sent for PGS
Sent in IVF round 3 and 6 (4 embryos) for PGS testing and got 2 normal embryos!!! 1Boy and 1Girl. Took a little over a year to get those two embryos so demanded all sorts of test prior to attempting transfer. Did EFT, ERA and NK Cells testing.
FET#1 - Intralipid drips, Prednisone, and did a depot lupron shot before starting the FET protocol Chemical pregnancy FET#2 - PGS normal boy - BFN Natural pregnancy - cycle following the FET2???? Miscarriage at 8 weeks. viability scan had shown an enlarged yolk sac so I had been warned that it was likely not chromosonally normal
DEIVF cycle - picked a donor who is willing to be open! Her cycle resulted in in 4 PGS Normal embryos 1st transfer - chemical pregnancy 2nd transfer - success, May 17 2020 due date!
@hopefuljj- she said technically any scar tissue is mild ashermans but she really wasn’t concerned with the small amount I had. So I’m more just worried that on a cellular level the inflammation can mess up the biology of implantation. When are you thinking of another transfer?! I can’t remember if the two embryos are pgs tested?
History in Spoiler
Age: 32 (same with DH). Together since 2006, Married June 2013 and TTC since August 2015 Diagnosis: Mild Endo, DOR (AMH of 1.5), Poor Quality Eggs/embryos, Displaced Window of Implantation (ERA Post Receptive) March-May 2016: 1 TI and 2 IUIs- BFN June 2016- Laproscopy- found/removed mild endo and confirmed only 1 normal healthy ovary. August 2016- IVF #1 with Antagonist Protocol- Cancelled (2 lead follies), converted to IUI- BFN Oct-Nov 2016- IVF #2 with Estrogen Priming Micro Lupron Protocol, 2 eggs retrieved, day 3 transfer of 1- BFN January 2017- New RE, IVF#3 with Estrogen Priming Antagonist Protocol, 12 eggs, 8 mature, 6 fertilized, 2 day 5 early blasts transferred (none to freeze ), BFN May 2017- Sept 2017- Starting Donor Egg process! Waiting for donor to be available... and then she is pregnant at baseline Oct 2017- Donor #2: 25R, 22M,18F, 12 blasts frozen! Fresh transfer cancelled due to thin lining with fluid Nov 2017- Hysterscopy to remove polyp Dec 2017- DE FET #1 on 12/8 on 2 perfect blasts- BFN and devastated Jan-Mar 2018- ERA #1- Post receptive by 24 hours, ERA #2 RECEPTIVE with 4 days of Progesterone Apr 2018- DE FET cancelled for lining issues Jun 2018- DE FET #2 of two 1AA blasts- first BFP ever! Beta 10dp5dt- 378, Beta 14dp5dt- 2840, Beta 16dp5dt- 4035, beta 18dp5dt- 10916. Due on 2/20 with one baby after a vanishing twin Baby Born born early @ 33.5 weeks due to Pre-e Back for # 2!
@JamieH2000 I’ll transfer whenever my doctor says I’m clear to! I’ve read 12 months postpartum and also 18, so I dunno! They are both PGS tested. I’m obviously very nervous with my track record that neither will work but I’m definitely going to do a natural cycle transfer again if I can and ignore my ERA results since that’s what finally worked for me!
Me: Hashimoto Autoimune Disease Homozygous MTHFR Cr677 DOR - AMH .27 High FSH (don't even know how high) 2 iui's to start - BFN IVF 1 -3 made it do day 5! 2 5AA 1 6BB PGS results = all abnormal IVF 2 - stimmed for 19 days. insanity. Had 5 follicles that looked mature but only 2 contained mature eggs the others were empty. Nothing made it to day 5 IVF 3 - added in HGH - 4 mature follicles (had some empties again) 3 made it to day 5/6 for PGS (held for testing with next retrieval IVF 4 - Upped my dosage for the first time - Canceled 11 days into sims - looked like 1 follicle and we were afraid it was empty IVF 5 - Canceled - looked like 1 follicle and we were afraid it was empty IVF 6 - 3 mature, 2 fertalized 1 made it to day 5 and sent for PGS
Sent in IVF round 3 and 6 (4 embryos) for PGS testing and got 2 normal embryos!!! 1Boy and 1Girl. Took a little over a year to get those two embryos so demanded all sorts of test prior to attempting transfer. Did EFT, ERA and NK Cells testing.
FET#1 - Intralipid drips, Prednisone, and did a depot lupron shot before starting the FET protocol Chemical pregnancy FET#2 - PGS normal boy - BFN Natural pregnancy - cycle following the FET2???? Miscarriage at 8 weeks. viability scan had shown an enlarged yolk sac so I had been warned that it was likely not chromosonally normal
DEIVF cycle - picked a donor who is willing to be open! Her cycle resulted in in 4 PGS Normal embryos 1st transfer - chemical pregnancy 2nd transfer - success, May 17 2020 due date!
@lmajin99- no it’s not much different as I did an antiobtioc and steroid in June since that’s the protocol that worked for me last time. So, another reason I’m not feeling totally confident. I really ww resolved the underlying endometritis problem or I don’t think it will work again..
@hopefuljj- I forget- did you have a c section? My clinic is 6 months for vaginal but I think 12 for c section. Maybe 18. But hopefully not!! I would def do what worked last time. But really consider a hysterscopy and biopsy before. I have lost faith in saline’s really. And it seems endometritis is so much more common after birth. So def worth checking before trying for number two
History in Spoiler
Age: 32 (same with DH). Together since 2006, Married June 2013 and TTC since August 2015 Diagnosis: Mild Endo, DOR (AMH of 1.5), Poor Quality Eggs/embryos, Displaced Window of Implantation (ERA Post Receptive) March-May 2016: 1 TI and 2 IUIs- BFN June 2016- Laproscopy- found/removed mild endo and confirmed only 1 normal healthy ovary. August 2016- IVF #1 with Antagonist Protocol- Cancelled (2 lead follies), converted to IUI- BFN Oct-Nov 2016- IVF #2 with Estrogen Priming Micro Lupron Protocol, 2 eggs retrieved, day 3 transfer of 1- BFN January 2017- New RE, IVF#3 with Estrogen Priming Antagonist Protocol, 12 eggs, 8 mature, 6 fertilized, 2 day 5 early blasts transferred (none to freeze ), BFN May 2017- Sept 2017- Starting Donor Egg process! Waiting for donor to be available... and then she is pregnant at baseline Oct 2017- Donor #2: 25R, 22M,18F, 12 blasts frozen! Fresh transfer cancelled due to thin lining with fluid Nov 2017- Hysterscopy to remove polyp Dec 2017- DE FET #1 on 12/8 on 2 perfect blasts- BFN and devastated Jan-Mar 2018- ERA #1- Post receptive by 24 hours, ERA #2 RECEPTIVE with 4 days of Progesterone Apr 2018- DE FET cancelled for lining issues Jun 2018- DE FET #2 of two 1AA blasts- first BFP ever! Beta 10dp5dt- 378, Beta 14dp5dt- 2840, Beta 16dp5dt- 4035, beta 18dp5dt- 10916. Due on 2/20 with one baby after a vanishing twin Baby Born born early @ 33.5 weeks due to Pre-e Back for # 2!
@JamieH2000 that is good news and reassuring that the other docs agree.
@Imajin99 we leave on Wednesday and we are flying. I just booked a facial at the spa. I'm pretty jazzed about the whole trip.
History and blog link in spoiler
2016 - dx with super low ovarian reserve; failed cycle with clomid, failed IUI, 2017 - egg retrieval #1 - 3 eggs, 0 embryos appropriate for transfer; ER #2 2 eggs, 0 embryos on day 3; ER #3 1 egg 0 embryos moved to donor egg in summer 2017; 35 eggs retrieved; 19 fertilized; 9 total embryos Fresh transfer Dec 2017= BFP! baby boy born 8/22/18
May 2019 - surprise natural pregnancy ended in MC Nov 2019 FET; MC at 9 weeks May 2020 FET; BFN July 2020 FET; CP treated with methotrexate Oct 2020 BFP!
@JamieH2000 @hopefuljj My clinic is similar, 6 mos pp for vaginal, or 12 mos pp for c-section, plus fully weaned. But then my old Ob was very conservative when it came to hopefully VBACing, so she didn't want me to transfer until the deliveries would be at least 24 mos apart, so that's more like 15 mos pp.
Luckily, I got a second Obs opinion, bc that was playing it perhaps overly cautious? And in my case, would have significant financial ramifications, were we to keep waiting those few extra months.
<div class=" Spoiler">We were cleared and started to transfer at 12 mos, which failed, but we still had time for a few more attempts before my insurance turned over for the year, which is what I was hoping for.</div> And I safely vbaced as 23 mos PP, FWIW. If you are going for a repeat section, it may not matter quite so much. GL!
@JamieH2000 yup failed induction and loads of complications led to a c-section. ans I’m likely going to push for a hysterscopy and biopsy prior to transfer I think cuz I’m crazy paranoid.
@BusinessWife thank you!!!! Yes I believe after my first failed induction and all the trauma that came along with it I would likely go for another section, which is insane to even write because I was so desperately not wanting one originally! I’m very impressed that you were able to do a vbac:)
@laurad75 your trip sounds like it is going to be amazing!
Me: Hashimoto Autoimune Disease Homozygous MTHFR Cr677 DOR - AMH .27 High FSH (don't even know how high) 2 iui's to start - BFN IVF 1 -3 made it do day 5! 2 5AA 1 6BB PGS results = all abnormal IVF 2 - stimmed for 19 days. insanity. Had 5 follicles that looked mature but only 2 contained mature eggs the others were empty. Nothing made it to day 5 IVF 3 - added in HGH - 4 mature follicles (had some empties again) 3 made it to day 5/6 for PGS (held for testing with next retrieval IVF 4 - Upped my dosage for the first time - Canceled 11 days into sims - looked like 1 follicle and we were afraid it was empty IVF 5 - Canceled - looked like 1 follicle and we were afraid it was empty IVF 6 - 3 mature, 2 fertalized 1 made it to day 5 and sent for PGS
Sent in IVF round 3 and 6 (4 embryos) for PGS testing and got 2 normal embryos!!! 1Boy and 1Girl. Took a little over a year to get those two embryos so demanded all sorts of test prior to attempting transfer. Did EFT, ERA and NK Cells testing.
FET#1 - Intralipid drips, Prednisone, and did a depot lupron shot before starting the FET protocol Chemical pregnancy FET#2 - PGS normal boy - BFN Natural pregnancy - cycle following the FET2???? Miscarriage at 8 weeks. viability scan had shown an enlarged yolk sac so I had been warned that it was likely not chromosonally normal
DEIVF cycle - picked a donor who is willing to be open! Her cycle resulted in in 4 PGS Normal embryos 1st transfer - chemical pregnancy 2nd transfer - success, May 17 2020 due date!
@laurad75 - How are you doing with the wait girl? This is the Blackberry Farms trip you're going on soon right? OMG so jealous. ladyp0tterandreamm31 - Did you ladies have your baselines/start estrogen or do you have to get PGS results first?
@c-town18 - We did our baseline's last Tuesday and we started estrogen the next day. We JUST got our PGS results today!! I will let Andrea share hers, but I got 5 normal embabies!! 2 boys and 3 girls. My hatching AA blast is a boy too so I am SUPER excited!! Praying hard he makes it for transfer and sticks!!
Me: 45yo, DH: 47yo 3 Daughters (singleton @27yo, ID Di/Di Twins @34yo) Protein S Deficiency (Blood Clotting Disorder), MTHFR & VIT D issue 5 MC's: Blighted Ovum-D&C @ 9wks; Natural MC @ 7wks; Blighted Ovum-D&C @ 9wks; MC boy-D&C @ 9wks & Chem PG in 2019 Tubes were tied after my Twins (and now I am old). Remarried and want to give my DH a baby!
IVF#1 OE June 2019 - ER 6/15/19, 24R, 21M, 20F, 7 6DBlasts Frozen for PGS Testing, RESULTS of PGS 4 abnormal girls, 2 abnormal boys, 1 indeterminate girl FET#1 OE August 23, 2019 (transferring 1 indeterminate girl & 1 abnormal boy) - BFN IVF#2 November 15, 2019 - ER 9R, 9M, 6F, 2 5dBlasts (fresh transfer) and 1 6DBlast frozen for PGS Testing, FRESH Transfer: November 20, 2019, 2 5-day blasts transferred!! BFP 8dp5dt on 11/27 - 12/2 on FRER, BETA #1 12/2 - 11.93. BETA #2 12/4: 4.41 ~CHEMICAL PG ******************Starting Donor Process June 2020: Egg Donor Cycle and Fresh Transfer of 1 embryo in Czech Republic - CANCELLED DUE TO COVID19 October 2020. Split Cycle at UFC with a friend (Andrea) I met on the Bump who was also supposed to go to Prague too DE Retrieval9/26/2020, 26R, 24M, 12 split Cycle, 9 Fertilized + 1 "questionable", PRAYING FOR AT LEAST 5 BLASTS 10/1/2020: 4 5DBlasts (AA, BB, BC, BC), 10/2/2020: 3 6DBlasts (BB, BB, BC) FOR A TOTAL OF: 7 BLASTS!! THANK YOU GOD!! PGS RESULTS: 5 NORMALS! DAY 5: AA BOY, BB GIRL, BC BOY / DAY 6: BB GIRL, BC GIRL DE FETOctober 29, 2020 - CANCELED DUE TO FLUID IN LINING DE FET November 16th, 2020 (transferring an PGS normal Hatching AA Boy)
@ladypotter- omg yay!! Been waiting to hear the good news from you guys!! Transfer will be here before you know it!!!
History in Spoiler
Age: 32 (same with DH). Together since 2006, Married June 2013 and TTC since August 2015 Diagnosis: Mild Endo, DOR (AMH of 1.5), Poor Quality Eggs/embryos, Displaced Window of Implantation (ERA Post Receptive) March-May 2016: 1 TI and 2 IUIs- BFN June 2016- Laproscopy- found/removed mild endo and confirmed only 1 normal healthy ovary. August 2016- IVF #1 with Antagonist Protocol- Cancelled (2 lead follies), converted to IUI- BFN Oct-Nov 2016- IVF #2 with Estrogen Priming Micro Lupron Protocol, 2 eggs retrieved, day 3 transfer of 1- BFN January 2017- New RE, IVF#3 with Estrogen Priming Antagonist Protocol, 12 eggs, 8 mature, 6 fertilized, 2 day 5 early blasts transferred (none to freeze ), BFN May 2017- Sept 2017- Starting Donor Egg process! Waiting for donor to be available... and then she is pregnant at baseline Oct 2017- Donor #2: 25R, 22M,18F, 12 blasts frozen! Fresh transfer cancelled due to thin lining with fluid Nov 2017- Hysterscopy to remove polyp Dec 2017- DE FET #1 on 12/8 on 2 perfect blasts- BFN and devastated Jan-Mar 2018- ERA #1- Post receptive by 24 hours, ERA #2 RECEPTIVE with 4 days of Progesterone Apr 2018- DE FET cancelled for lining issues Jun 2018- DE FET #2 of two 1AA blasts- first BFP ever! Beta 10dp5dt- 378, Beta 14dp5dt- 2840, Beta 16dp5dt- 4035, beta 18dp5dt- 10916. Due on 2/20 with one baby after a vanishing twin Baby Born born early @ 33.5 weeks due to Pre-e Back for # 2!
Me: Hashimoto Autoimune Disease Homozygous MTHFR Cr677 DOR - AMH .27 High FSH (don't even know how high) 2 iui's to start - BFN IVF 1 -3 made it do day 5! 2 5AA 1 6BB PGS results = all abnormal IVF 2 - stimmed for 19 days. insanity. Had 5 follicles that looked mature but only 2 contained mature eggs the others were empty. Nothing made it to day 5 IVF 3 - added in HGH - 4 mature follicles (had some empties again) 3 made it to day 5/6 for PGS (held for testing with next retrieval IVF 4 - Upped my dosage for the first time - Canceled 11 days into sims - looked like 1 follicle and we were afraid it was empty IVF 5 - Canceled - looked like 1 follicle and we were afraid it was empty IVF 6 - 3 mature, 2 fertalized 1 made it to day 5 and sent for PGS
Sent in IVF round 3 and 6 (4 embryos) for PGS testing and got 2 normal embryos!!! 1Boy and 1Girl. Took a little over a year to get those two embryos so demanded all sorts of test prior to attempting transfer. Did EFT, ERA and NK Cells testing.
FET#1 - Intralipid drips, Prednisone, and did a depot lupron shot before starting the FET protocol Chemical pregnancy FET#2 - PGS normal boy - BFN Natural pregnancy - cycle following the FET2???? Miscarriage at 8 weeks. viability scan had shown an enlarged yolk sac so I had been warned that it was likely not chromosonally normal
DEIVF cycle - picked a donor who is willing to be open! Her cycle resulted in in 4 PGS Normal embryos 1st transfer - chemical pregnancy 2nd transfer - success, May 17 2020 due date!
@laurad75 OMG! Sending you soooo much baby dust. Cant wait to hear about your first test!!! You got this girlie! Hoping you have the most amazing trip!
@JamieH2000. Dang girl....I read back and you have so much going on! Im sorry you have so much uncertainty. I think the steroids are really going to be helpful. It sounds like you have a lot of histamine in your system with your allergies like that and the tissue. I wonder if an antihistamine would also be helpful for you. Like Claritin or Allegra ....which ever one is ok during pregnancy (I think they both are). There are histamine containing foods you should stay away from too....I would google it, but I know Kombucha is high in histamine. This will help decrease inflammation too. I think you gotta just go with it. you did all the antibiotics, and it sounds like your RE has a good plan. I would do it too! 4.5 weeks will be here so soon!
@hopefuljj That is so exciting you are starting to think about #2!
AFM: We got 6 PGS normal embryos, 3 boys and 3 girls from 10 Embryos! We had one that was untested because there wasn't enough DNA, but its also my day 6 BC, so I will probably not use that one unless I was desperate. Going to transfer an AB GIRL! Really excited and so happy with these results. I just know my babies now EXIST on this earth. Its so crazy and miraculous. I feel so much positive energy and calmness around all of this which is usually my sign that things are just going to work out and bring me my babies! Im obviously so thrilled that Gina got so many too. Man, we are so freaking blessed with the donor they suggested for us. Transfer is in 2.5 weeks!
39 years old DH 41. Sperm looks great. We live in San Diego Me: ****TW loss mentioned*** MTHFR Homozygous 677TT (dx 2016) hypothyroid 8/2018 Off birth control 11/29/2018 CP 2/10/2019. CP 3/8/2019 Saw fertility doctor, AFC 5, labs drawn 3/14/2019 Pregnant 4/18/2019 9 week ultrasound MM , stopped growing at 6 weeks, no HB. D&C 5/2/2019 Return to fertility doctor, labs show AMH 0.27. Diminished Ovarian Reserve 1st of 3 Egg retrievals planned tentatively for July 6/29/2019 started Antagonist Protocol 7/12/2019 First egg retrieval, only retrieved one egg and fell apart immediately, poor quality. 8/7/2019. Second cycle (follicular antagonist) canceled on day 5 of stims when a very large lead follicle grew out of nowhere. 11/8/2019. Second Egg retrieval with Lupron Flare Protocol. 2 eggs retrieved, fertilized with ICSI but no reaction occurred at all. Told I will never have my own babies with my eggs. 12/20/2019 ERA - pre-receptive. Needed 24 hours more of progesterone 2/2020 CP 3/2/2020 Egg donor cycle in Prague at Unica Clinic, 2 AA embryos, 1 transfer, 1 on ice. BFN. Due to pandemic, we could not return to Prague and will abandon our remaining embryo. 4/20/2020. BFP trying on our own! 06/04/2020 After HBs at 7 and 9 weeks, MM at 10 weeks 3 days. D&C, Hemorrhaged out 1 liter of blood from uterine artery rupture during procedure. Spent 1 night in the hospital with a balloon tamponade in my uterus. Baby was mosaic Trisomy 21. 8/2020. Moving forward with Donor Egg cycle at Utah Fertility Center and sharing a cycle with ladypOtter (Gina) I met on the Bump who was also supposed to go to Prague but couldn't. 9/26/2020 Donor retrieval of 26 eggs, 24 mature. Split cycle so I have 12 eggs with all 12 fertilizing. 6 PGS normal 3 boys, 3 girls 10/29/2020 Transfer day of girl donor egg embryo. BFP! First HCG 92.9. Then inappropriate rise, plateau and falling. Possibly ectopic pregnancy. ER visit with diagnosis of "pregnancy location unknown". CP 1/19/2021 Embryos shipped from Utah to my local clinic, starting prednisone for anti-histamine protocol. 2/26/2021 FET girl embryo BFP. Betas 62, 139, 386! HB at 6 weeks, then baby stopped growing at 8 week check up with weak HB measuring 6 weeks 4 days. MM at 9 weeks. D&C 4/15/21 7/13/2021 FET boy and girl embryos. First beta 10dp5dt 177, 14dp5dt 1631, 16dp5dt 6809. Pregnant with Identical triplets. At 9 weeks, Baby C no longer had a heart beat. Identical Twin Girls. Pregnancy complicated by TRAP Sequence with baby C an Acardiac fetus still receiving blood flow being pumped to it by other girls. Referred to UCSF at 18 weeks for consultation. No intervention needed at this time 2/18/22 After a failed NST, at 34 weeks 1 day, Charlotte born 4lb 4oz and Lily born 4lbs 10 oz. Our hearts are complete. Baby girls in NICU to grow and learn to eat.
@laurad75 The trip sounds amazing and the perfect way to keep your mind occupied! Although if you do test and get a BFP, it will sorta suck that you can't drink any wine! I actually got my first natural BFP three days before our annual trip to France and so I couldn't eat anything unpasteurized (cheese, yogurts, etc) or any wine (which is so hard in France!). I miss traveling soooo much; it is always filled with so many surprises and exciting times (plus relaxing too!). DH is pretty strict on covid measures so we haven't gone anywhere in awhile. We're already planning our next trip (to Disney, it's near to us and kid friendly) which we will hopefully be able to do this upcoming spring (fx for having some kind of vaccine out by then). Of course, the idea of Disney while heavily pregnant doesn't sound much fun to me (if we transfer beforehand and are fortunate, of course).
@JamieH2000 My RE actually has a steroid course and antibiotic course prior to transfer just to be on the safe side -- did yours do that before? There are some old wives' tales that anti-histamines can also help with conception (some ladies claim taking antihistamines during their cycle was the reason for their success). If you don't mind the side effects, benadryl is considered safe in pregnancy (and often used for sleep issues), so maybe a tab before bed might be some extra security if you want it?
@andreamm31 Awesome numbers! That your babies exist on this planet now is such a good feeling. I was really down during my IVF cycle so I didn't have many moments of excitement like that, but I hope that you, like me, will look back next year while you're holding your baby on this same day and think of this time. It's super surreal how those little embies turn into our little girls and boys.
@ladyp0tter Great results and a hatching blast is the best!! Mine were hatching after they thawed and my embryologist was thrilled, saying that's the best possible sign. Fx for a little boy for you!
AFM we're hopefully going to get a closing date on our refinance in the next week or so since our docs are now in underwriting -- we're refinancing the mortgage and rolling our HELOC into it, and getting a cash out for our roof replacement and fertility stuff - so we're possibly looking at a November start unless I decide to wait until January after the holidays. I pulled a few journal studies on BCP and low AMH for my RE so we can discuss that; his major sticking point is that I've been super irregular and my AFC and FSH are still OK. With an AMH of 0.62 last time and doing a mini-stim, we got 10 eggs (9 mature) so he doesn't feel there's any reason to be overly concerned about suppression. He wants me to focus on quality rather than quantity so I've already started taking some supplements (vitamin d, coq10, DHEA, etc) and taking out some of the processed garbage out of my diet. I also have to get off one of the meds I take for anxiety (started it postpartum) so I've been working with my therapist a bunch on methods to cope if I do have a rebound after going off it. Last time I tried to drop it, I got a nasty rebound of anxiety/depression.
~~ Our Story in Spoiler! TW loss/child~~
Fall 2012 -- started TTC Summer 2015 - no BFP yet, labs normal, referred to RE Fall 2015 - Summer 2016 - Further testing all normal. 3 IUI's -- BFN. Recommended move to IVF. Planned cycle for fall 2016. September 2016 - Surprise natural BFP. MMC @ 8 weeks. RE expressed confidence that we just needed the 'right' embryo. Fall 2016 - Spring 2017 -- Break from TTC June 2017 - Started IVF; egg retrieval for freeze all cycle. 9 mature eggs retrieved, 5 fertilized. 2 4BB embies on ice. August 2017 - FET transfer both embies. BFP. Twin pregnancy confirmed by ultrasound. EDD 4/28/18 September 2017 - Twin B stopped developing; Twin A doing perfectly! Graduated from RE @ 10 weeks March 2018 - Baby Girl born via C/S due to pre-eclampsia -- strong and healthy!
TTC #2 January/Feb 2021 - Freeze-all IVF cycle March 2021 - FET of 1 PGS normal female embryo. BFP! Beta #1 156, #2 472, #3 1241, #4 5268 EDD 12/5/21 - Christmas baby!
@andreamm31- omg 6 is so good too! Gosh so happy for you both. And so hoping the transfers work for both of you ladies!! Soo soon!! Donor eggs is no easy journey but it’s soo worth it!! Those are your babies!! thanks for the advice on the antihistamine! I have been on allergy daily since spring (I am every summer) but maybe it’s not working as good anymore.. tho a lot of people in my area are complaining about the worst fall allergy season ever. I sure hope this is it for us. Not sure how I can keep going thru this (tho I know I will bc the end result is worth all the pain)...
@mbradfo2- yup my procotol has always had the steroid and antiobtioc so hopefully the reason for the last chemical was the polyp and scar tissue... I think it’s good to discuss the studies with your RE. If you are flexible with timing, it may be ok to wait for your natural cycle... has it been irregular since the birth? It would suggest something is off hormonally since I don’t think you are heading into menopause or anything with your numbers... I guess you could always do BC and if the baseline showed reduced AFC or they didn’t respond , then you could just cancel. But it is such a disappointing thing to go thru
History in Spoiler
Age: 32 (same with DH). Together since 2006, Married June 2013 and TTC since August 2015 Diagnosis: Mild Endo, DOR (AMH of 1.5), Poor Quality Eggs/embryos, Displaced Window of Implantation (ERA Post Receptive) March-May 2016: 1 TI and 2 IUIs- BFN June 2016- Laproscopy- found/removed mild endo and confirmed only 1 normal healthy ovary. August 2016- IVF #1 with Antagonist Protocol- Cancelled (2 lead follies), converted to IUI- BFN Oct-Nov 2016- IVF #2 with Estrogen Priming Micro Lupron Protocol, 2 eggs retrieved, day 3 transfer of 1- BFN January 2017- New RE, IVF#3 with Estrogen Priming Antagonist Protocol, 12 eggs, 8 mature, 6 fertilized, 2 day 5 early blasts transferred (none to freeze ), BFN May 2017- Sept 2017- Starting Donor Egg process! Waiting for donor to be available... and then she is pregnant at baseline Oct 2017- Donor #2: 25R, 22M,18F, 12 blasts frozen! Fresh transfer cancelled due to thin lining with fluid Nov 2017- Hysterscopy to remove polyp Dec 2017- DE FET #1 on 12/8 on 2 perfect blasts- BFN and devastated Jan-Mar 2018- ERA #1- Post receptive by 24 hours, ERA #2 RECEPTIVE with 4 days of Progesterone Apr 2018- DE FET cancelled for lining issues Jun 2018- DE FET #2 of two 1AA blasts- first BFP ever! Beta 10dp5dt- 378, Beta 14dp5dt- 2840, Beta 16dp5dt- 4035, beta 18dp5dt- 10916. Due on 2/20 with one baby after a vanishing twin Baby Born born early @ 33.5 weeks due to Pre-e Back for # 2!
Thanks gang. Ugh the wait sucks and I'm trying so hard to stay positive and think positive but then my mind gets the best of me and I start to spiral. We leave first thing in the morning and I can't wait.
History and blog link in spoiler
2016 - dx with super low ovarian reserve; failed cycle with clomid, failed IUI, 2017 - egg retrieval #1 - 3 eggs, 0 embryos appropriate for transfer; ER #2 2 eggs, 0 embryos on day 3; ER #3 1 egg 0 embryos moved to donor egg in summer 2017; 35 eggs retrieved; 19 fertilized; 9 total embryos Fresh transfer Dec 2017= BFP! baby boy born 8/22/18
May 2019 - surprise natural pregnancy ended in MC Nov 2019 FET; MC at 9 weeks May 2020 FET; BFN July 2020 FET; CP treated with methotrexate Oct 2020 BFP!
Has anyone ever had issues traveling with medication - specifically syringes? I was planning to put my meds in a zip lock back and putting them through security separately.
History and blog link in spoiler
2016 - dx with super low ovarian reserve; failed cycle with clomid, failed IUI, 2017 - egg retrieval #1 - 3 eggs, 0 embryos appropriate for transfer; ER #2 2 eggs, 0 embryos on day 3; ER #3 1 egg 0 embryos moved to donor egg in summer 2017; 35 eggs retrieved; 19 fertilized; 9 total embryos Fresh transfer Dec 2017= BFP! baby boy born 8/22/18
May 2019 - surprise natural pregnancy ended in MC Nov 2019 FET; MC at 9 weeks May 2020 FET; BFN July 2020 FET; CP treated with methotrexate Oct 2020 BFP!
I haven't, @laurad75 but I'm sure it happens more often than you might think for various reasons, diabetics etc. I think if you have the meds and syringes set aside, and declare them, it should be no trouble. Hopefully you just get an agent with half a brain 🙄 lol Flying these days is not my favorite...
@laurad75 Just make sure the meds all are labelled with the doctor's prescription and I would ask for a note from your RE's office listing what medications were prescribed and that they are administered by injection, just to be on the safe side. Depending on the TSA agent, it will either be smooth or a pain. Unused needles and syringes for prescribed medication are allowed through security as long as they are accompanied by the medicine.
~~ Our Story in Spoiler! TW loss/child~~
Fall 2012 -- started TTC Summer 2015 - no BFP yet, labs normal, referred to RE Fall 2015 - Summer 2016 - Further testing all normal. 3 IUI's -- BFN. Recommended move to IVF. Planned cycle for fall 2016. September 2016 - Surprise natural BFP. MMC @ 8 weeks. RE expressed confidence that we just needed the 'right' embryo. Fall 2016 - Spring 2017 -- Break from TTC June 2017 - Started IVF; egg retrieval for freeze all cycle. 9 mature eggs retrieved, 5 fertilized. 2 4BB embies on ice. August 2017 - FET transfer both embies. BFP. Twin pregnancy confirmed by ultrasound. EDD 4/28/18 September 2017 - Twin B stopped developing; Twin A doing perfectly! Graduated from RE @ 10 weeks March 2018 - Baby Girl born via C/S due to pre-eclampsia -- strong and healthy!
TTC #2 January/Feb 2021 - Freeze-all IVF cycle March 2021 - FET of 1 PGS normal female embryo. BFP! Beta #1 156, #2 472, #3 1241, #4 5268 EDD 12/5/21 - Christmas baby!
laurad75 - I have flown a lot with meds (plus syringes) and never had a problem. I just always keep the syringes with the meds and make sure the Rx label is visible.
@ladyp0tter@andreamm31 - congrats, ladies!!!! Those are amazing results!!! If you think of it - those are 11 normal embies total from just one cycle!!! Crazy!!! Very excited for you both, and sending lots of sticky vibes for the transfers
----------------------------------------------------------------------------------------------------- My story in signature spoiler. Children mentioned.
Me: 37 DH: 45 I don't produce FSH, so no natural menstrual cycle. DH has reduced morphology. Summer 2014 IUI (with first husband): cancelled after almost a month of stims due to too many follicles Time off to divorce, get back on my feet, find a new hubby and get married again 💑 March 2017 IVF#1: ~70 follicles, 13R, 10M, 7F, 3B = 2 PGS Normal (both XY) - no transfer due to ohss Sept 2017 FET#1: BFP, Beta#1 (10dpt) - 253, Beta#2 (12dpt) - 528, DS born 05/31/2018 👨👩👦 Dec 2019 FET#2: BFN Changed clinic, planning March 2020 IVF#2 - postponed due to the pandemic April 2020 IVF #2: ~30 follicles, 24R, 12M, 8F, 4B = 2XY & 2XX, all normal Sept 2020 FET#3: one XX embryo, BFP, Beta#1 (9dpt) - 161, Beta#2 (11dpt) - 519, Beta#3 (19dpt) - 7174, Due date 05/30/2021 DD born 05/23/2021 👨👩👧👦 - My family is now complete
@andreamm31 woohoo!!!! Yay girl! Amazing!!! So happy for you!!!
@JamieH2000 the antihistamine protocol that’s was maybe what andreamm31 was referencing requires you take Benadryl but also Pepcid on a specific schedule. So I don’t think a regular antihistamine is as effective, just an FYI!!
@laurad75 ugh the wait is the worst!! Hang in there lady!!!!
Me: Hashimoto Autoimune Disease Homozygous MTHFR Cr677 DOR - AMH .27 High FSH (don't even know how high) 2 iui's to start - BFN IVF 1 -3 made it do day 5! 2 5AA 1 6BB PGS results = all abnormal IVF 2 - stimmed for 19 days. insanity. Had 5 follicles that looked mature but only 2 contained mature eggs the others were empty. Nothing made it to day 5 IVF 3 - added in HGH - 4 mature follicles (had some empties again) 3 made it to day 5/6 for PGS (held for testing with next retrieval IVF 4 - Upped my dosage for the first time - Canceled 11 days into sims - looked like 1 follicle and we were afraid it was empty IVF 5 - Canceled - looked like 1 follicle and we were afraid it was empty IVF 6 - 3 mature, 2 fertalized 1 made it to day 5 and sent for PGS
Sent in IVF round 3 and 6 (4 embryos) for PGS testing and got 2 normal embryos!!! 1Boy and 1Girl. Took a little over a year to get those two embryos so demanded all sorts of test prior to attempting transfer. Did EFT, ERA and NK Cells testing.
FET#1 - Intralipid drips, Prednisone, and did a depot lupron shot before starting the FET protocol Chemical pregnancy FET#2 - PGS normal boy - BFN Natural pregnancy - cycle following the FET2???? Miscarriage at 8 weeks. viability scan had shown an enlarged yolk sac so I had been warned that it was likely not chromosonally normal
DEIVF cycle - picked a donor who is willing to be open! Her cycle resulted in in 4 PGS Normal embryos 1st transfer - chemical pregnancy 2nd transfer - success, May 17 2020 due date!
Greetings from the smoky mountains! I hate posting on the app but I’m making an exception today. BTW, it was no prob going through the security at the airport. They didn’t even want me to take the meds out of my bag.
My update in spoiler:
I tested this morning. At 7dp5dt it’s the longest I’ve held out so I’m rather proud of myself. It was a strong BFP. I have ZERO symptoms. Nothing. So I was worried but there was no mistaking that line. Yay! H and I are going hiking today so I’m going to tell him then. I have been down this road before so I’m still cautious but as I have said I just had a feeling about this embryo.
History and blog link in spoiler
2016 - dx with super low ovarian reserve; failed cycle with clomid, failed IUI, 2017 - egg retrieval #1 - 3 eggs, 0 embryos appropriate for transfer; ER #2 2 eggs, 0 embryos on day 3; ER #3 1 egg 0 embryos moved to donor egg in summer 2017; 35 eggs retrieved; 19 fertilized; 9 total embryos Fresh transfer Dec 2017= BFP! baby boy born 8/22/18
May 2019 - surprise natural pregnancy ended in MC Nov 2019 FET; MC at 9 weeks May 2020 FET; BFN July 2020 FET; CP treated with methotrexate Oct 2020 BFP!
Re: Low AMH Level
I had a good convo with my RE. WE talked about so much. I wish I could remember it all. Basically, we have tried all 5 classes of antibiotics, so i really shouldn't have an infection anymore. We have cleaned out the inflammation tissue, and then biopsy she sent was a polyp, so of course it came as as endometritis. She is hopeful the uterus is ready to go. She wonders if the inflammation is maybe an immune thing and not an infection? Her plan would be to transfer and add in doxycycline and a steroid during the cycle to help with anymore possible infection or inflammation. She is also doing some more research since there was some allergic reaction found in my biopsy too? SHe put my case up for review this week with the 10 other physicians in the practice. Honestly, I think we are doing everything we can. I'm very nervous to transfer though. I read too much on the internet how unresolved endometritis can hurt implantation and increase miscarriage. but I also know the longer we wait, the more likely polyps or scar tissue would come back and we would need another hysterscopy. So if none of the other doctors have any big insights, i think we will probably try to transfer in Nov. If it doesn't work, I guess its back to biopsies and more meds. Ugh. She made me feel more hopeful in that she has a handful of patients dealing with this at any given time, and she said most go on to be successful. She was confident i would have success in the end. So I'm just gonna try to trust her plan once we finalize that.
Diagnosis: Mild Endo, DOR (AMH of 1.5), Poor Quality Eggs/embryos, Displaced Window of Implantation (ERA Post Receptive)
March-May 2016: 1 TI and 2 IUIs- BFN
June 2016- Laproscopy- found/removed mild endo and confirmed only 1 normal healthy ovary.
August 2016- IVF #1 with Antagonist Protocol- Cancelled (2 lead follies), converted to IUI- BFN
Oct-Nov 2016- IVF #2 with Estrogen Priming Micro Lupron Protocol, 2 eggs retrieved, day 3 transfer of 1- BFN
January 2017- New RE, IVF#3 with Estrogen Priming Antagonist Protocol, 12 eggs, 8 mature, 6 fertilized, 2 day 5 early blasts transferred (none to freeze
May 2017- Sept 2017- Starting Donor Egg process! Waiting for donor to be available... and then she is pregnant at baseline
Oct 2017- Donor #2: 25R, 22M,18F, 12 blasts frozen! Fresh transfer cancelled due to thin lining with fluid
Nov 2017- Hysterscopy to remove polyp
Dec 2017- DE FET #1 on 12/8 on 2 perfect blasts- BFN and devastated
Jan-Mar 2018- ERA #1- Post receptive by 24 hours, ERA #2 RECEPTIVE with 4 days of Progesterone
Apr 2018- DE FET cancelled for lining issues
Jun 2018- DE FET #2 of two 1AA blasts- first BFP ever! Beta 10dp5dt- 378, Beta 14dp5dt- 2840, Beta 16dp5dt- 4035, beta 18dp5dt- 10916. Due on 2/20 with one baby after a vanishing twin
Baby Born born early @ 33.5 weeks due to Pre-e
Back for # 2!
Thanks for the well wishes everyone. I'm feeling cautiously hopeful. I don't remember if I've shared this particular crazy thought but I have an embryo (4AB) that I assumed they were going to transfer last time but instead they transferred the 4BA. It doesn't really matter which one they put in but for some reason it confused me and it just felt 'wrong'. So, know I'm convinced that the 4AB is the one that is meant to be and won't that be a cool story if this is successful and if it's not successful whatever - it can't suck more than the other 3 failures. Right?
Will I test? That's a great question. We leave early next Wednesday which is 6dp5dt and when I would normally start testing. I would love to say I'm going to wait but I have literally never, not once in 4 transfers, been able to wait. I think with my first transfer I was able to hold out to 7dp5dt (fresh transfer). Maybe I'll try and wait until the morning after we get there (7days) and if it's negative I'll let myself have a glass of wine. Maybe I'll be too distracted and be able to hold out but I doubt it.
2017 - egg retrieval #1 - 3 eggs, 0 embryos appropriate for transfer; ER #2 2 eggs, 0 embryos on day 3; ER #3 1 egg 0 embryos
moved to donor egg in summer 2017; 35 eggs retrieved; 19 fertilized; 9 total embryos
Fresh transfer Dec 2017= BFP! baby boy born 8/22/18
May 2019 - surprise natural pregnancy ended in MC
Nov 2019 FET; MC at 9 weeks
May 2020 FET; BFN
July 2020 FET; CP treated with methotrexate
Oct 2020 BFP!
Take a look at my blog
JamieH2000 - If none of the other docs in your clinic have any further suggestions, and if your RE thinks it's a reasonable decision, I would totally transfer asap if I were you. You're battling a few different issues here between this and the polyps and the scar tissue and there may not ever be a time when everything is just right ya know? If you at least know the polyps and scar tissue are clear for the time being, I say jump on it. Ugh, I'm sorry you just can't catch a break here friend.
@JamieH2000 Ugh, so frustrating for you! It sounds good that your RE has experience with this and sees folks go on to have successful transfers. It is so hard to know what to do in this situation but it does sound like if she sent the polyp for testing, of course it's going to come back as inflamed. I know it sucks, but would testing any of the regular endometrial tissue give you a potentially different answer? I know that some REs have steroids as part of their transfer protocols, particularly for folks with autoimmune issues, so perhaps that could be very useful for you. It's so crazy that you could have this kind of thing and it's so hard to get rid of and you wouldn't even really know you had it except for a failed transfer. I'm interested to hear what the panel says about transfer...does your clinic keep any in house stats on that kind of thing? Anyway, I'm really rooting for you
@c-town18- my thoughts exactly. I'm interested in what the other REs will say. it will throw me for a bit of a loop if enough say not to transfer and my RE changes her mind. So kinda just waiting to hear until i get totally set on a transfer... though i am already kinda thinking in transfer mode (time to cut out diet soda, extra sugar, alcohol, etc- whatever i can do to lower inflammation, though i don't really beleive all of that makes much difference, but it can't hurt).
@lucyb1954- thanks friend!! i really wish she had tested a normal tissue to see if the inflammation cells were there. THough if they were, I'm not sure what we would do since we have done all the antibiotics. My transfer protocol has always had a steroid and antibiotic (its "old school" she said last time, but it worked, so we were keeping with it). So now we will do two antibiotics. I just hope if somehow the embryo sticks, we aren't at higher risk of loss. Reading the studies and science on it really freaked me out. They all showed much better results with the endometritis resolved. and we don't know if its resolved. But the studies also showed that the meds (usually just one or two antibiotics) cleared this for like everyone. So it does make me wonder if the inflammation is from some odd immune response. SHe is also starting me on a new vaginal probiotic today, in case the other one had some ingredient in that i was allergic to since they found Eosonofils, which are white blood cells evidence of allergies apparently? My seasonal fall allergies have been the worst in years this year, but not sure how my uterus would be showing that?!
Diagnosis: Mild Endo, DOR (AMH of 1.5), Poor Quality Eggs/embryos, Displaced Window of Implantation (ERA Post Receptive)
March-May 2016: 1 TI and 2 IUIs- BFN
June 2016- Laproscopy- found/removed mild endo and confirmed only 1 normal healthy ovary.
August 2016- IVF #1 with Antagonist Protocol- Cancelled (2 lead follies), converted to IUI- BFN
Oct-Nov 2016- IVF #2 with Estrogen Priming Micro Lupron Protocol, 2 eggs retrieved, day 3 transfer of 1- BFN
January 2017- New RE, IVF#3 with Estrogen Priming Antagonist Protocol, 12 eggs, 8 mature, 6 fertilized, 2 day 5 early blasts transferred (none to freeze
May 2017- Sept 2017- Starting Donor Egg process! Waiting for donor to be available... and then she is pregnant at baseline
Oct 2017- Donor #2: 25R, 22M,18F, 12 blasts frozen! Fresh transfer cancelled due to thin lining with fluid
Nov 2017- Hysterscopy to remove polyp
Dec 2017- DE FET #1 on 12/8 on 2 perfect blasts- BFN and devastated
Jan-Mar 2018- ERA #1- Post receptive by 24 hours, ERA #2 RECEPTIVE with 4 days of Progesterone
Apr 2018- DE FET cancelled for lining issues
Jun 2018- DE FET #2 of two 1AA blasts- first BFP ever! Beta 10dp5dt- 378, Beta 14dp5dt- 2840, Beta 16dp5dt- 4035, beta 18dp5dt- 10916. Due on 2/20 with one baby after a vanishing twin
Baby Born born early @ 33.5 weeks due to Pre-e
Back for # 2!
3 Daughters (singleton @27yo, ID Di/Di Twins @34yo)
Protein S Deficiency (Blood Clotting Disorder), MTHFR & VIT D issue
5 MC's: Blighted Ovum-D&C @ 9wks; Natural MC @ 7wks; Blighted Ovum-D&C @ 9wks; MC boy-D&C @ 9wks & Chem PG in 2019
Tubes were tied after my Twins (and now I am old). Remarried and want to give my DH a baby!
IVF#1 OE June 2019 - ER 6/15/19, 24R, 21M, 20F, 7 6DBlasts Frozen for PGS Testing,
RESULTS of PGS 4 abnormal girls, 2 abnormal boys, 1 indeterminate girl
FET#1 OE August 23, 2019 (transferring 1 indeterminate girl & 1 abnormal boy) - BFN
IVF#2 November 15, 2019 - ER 9R, 9M, 6F, 2 5dBlasts (fresh transfer) and 1 6DBlast frozen for PGS Testing,
FRESH Transfer: November 20, 2019, 2 5-day blasts transferred!!
BFP 8dp5dt on 11/27 - 12/2 on FRER, BETA #1 12/2 - 11.93. BETA #2 12/4: 4.41 ~CHEMICAL PG
******************Starting Donor Process
June 2020: Egg Donor Cycle and Fresh Transfer of 1 embryo in Czech Republic - CANCELLED DUE TO COVID19
October 2020. Split Cycle at UFC with a friend (Andrea) I met on the Bump who was also supposed to go to Prague too
DE Retrieval 9/26/2020, 26R, 24M, 12 split Cycle, 9 Fertilized + 1 "questionable", PRAYING FOR AT LEAST 5 BLASTS
10/1/2020: 4 5DBlasts (AA, BB, BC, BC), 10/2/2020: 3 6DBlasts (BB, BB, BC) FOR A TOTAL OF: 7 BLASTS!! THANK YOU GOD!!
PGS RESULTS: 5 NORMALS! DAY 5: AA BOY, BB GIRL, BC BOY / DAY 6: BB GIRL, BC GIRL
DE FET October 29, 2020 - CANCELED DUE TO FLUID IN LINING
DE FET November 16th, 2020 (transferring an PGS normal Hatching AA Boy)
Diagnosis: Mild Endo, DOR (AMH of 1.5), Poor Quality Eggs/embryos, Displaced Window of Implantation (ERA Post Receptive)
March-May 2016: 1 TI and 2 IUIs- BFN
June 2016- Laproscopy- found/removed mild endo and confirmed only 1 normal healthy ovary.
August 2016- IVF #1 with Antagonist Protocol- Cancelled (2 lead follies), converted to IUI- BFN
Oct-Nov 2016- IVF #2 with Estrogen Priming Micro Lupron Protocol, 2 eggs retrieved, day 3 transfer of 1- BFN
January 2017- New RE, IVF#3 with Estrogen Priming Antagonist Protocol, 12 eggs, 8 mature, 6 fertilized, 2 day 5 early blasts transferred (none to freeze
May 2017- Sept 2017- Starting Donor Egg process! Waiting for donor to be available... and then she is pregnant at baseline
Oct 2017- Donor #2: 25R, 22M,18F, 12 blasts frozen! Fresh transfer cancelled due to thin lining with fluid
Nov 2017- Hysterscopy to remove polyp
Dec 2017- DE FET #1 on 12/8 on 2 perfect blasts- BFN and devastated
Jan-Mar 2018- ERA #1- Post receptive by 24 hours, ERA #2 RECEPTIVE with 4 days of Progesterone
Apr 2018- DE FET cancelled for lining issues
Jun 2018- DE FET #2 of two 1AA blasts- first BFP ever! Beta 10dp5dt- 378, Beta 14dp5dt- 2840, Beta 16dp5dt- 4035, beta 18dp5dt- 10916. Due on 2/20 with one baby after a vanishing twin
Baby Born born early @ 33.5 weeks due to Pre-e
Back for # 2!
2017 - egg retrieval #1 - 3 eggs, 0 embryos appropriate for transfer; ER #2 2 eggs, 0 embryos on day 3; ER #3 1 egg 0 embryos
moved to donor egg in summer 2017; 35 eggs retrieved; 19 fertilized; 9 total embryos
Fresh transfer Dec 2017= BFP! baby boy born 8/22/18
May 2019 - surprise natural pregnancy ended in MC
Nov 2019 FET; MC at 9 weeks
May 2020 FET; BFN
July 2020 FET; CP treated with methotrexate
Oct 2020 BFP!
Take a look at my blog
AFM- finally some good news I guess? Sounds like the other docs agree we should move forward with the transfer. I got my calendar and so much on it!’ I take 3 types of estrogen and then lupron and then the antiobtiocs and steroid and of course PIo.. and aspirin too. Now I’m just hoping everything goes smoothly with my lining and transfer day is 4.5 weeks away!
Diagnosis: Mild Endo, DOR (AMH of 1.5), Poor Quality Eggs/embryos, Displaced Window of Implantation (ERA Post Receptive)
March-May 2016: 1 TI and 2 IUIs- BFN
June 2016- Laproscopy- found/removed mild endo and confirmed only 1 normal healthy ovary.
August 2016- IVF #1 with Antagonist Protocol- Cancelled (2 lead follies), converted to IUI- BFN
Oct-Nov 2016- IVF #2 with Estrogen Priming Micro Lupron Protocol, 2 eggs retrieved, day 3 transfer of 1- BFN
January 2017- New RE, IVF#3 with Estrogen Priming Antagonist Protocol, 12 eggs, 8 mature, 6 fertilized, 2 day 5 early blasts transferred (none to freeze
May 2017- Sept 2017- Starting Donor Egg process! Waiting for donor to be available... and then she is pregnant at baseline
Oct 2017- Donor #2: 25R, 22M,18F, 12 blasts frozen! Fresh transfer cancelled due to thin lining with fluid
Nov 2017- Hysterscopy to remove polyp
Dec 2017- DE FET #1 on 12/8 on 2 perfect blasts- BFN and devastated
Jan-Mar 2018- ERA #1- Post receptive by 24 hours, ERA #2 RECEPTIVE with 4 days of Progesterone
Apr 2018- DE FET cancelled for lining issues
Jun 2018- DE FET #2 of two 1AA blasts- first BFP ever! Beta 10dp5dt- 378, Beta 14dp5dt- 2840, Beta 16dp5dt- 4035, beta 18dp5dt- 10916. Due on 2/20 with one baby after a vanishing twin
Baby Born born early @ 33.5 weeks due to Pre-e
Back for # 2!
@JamieH2000 good grief on the endometritis!!! FFS!!! Ugh I wish they had tested other tissue to check for inflammation too. You could do an anti inflammation diet if you wanted to, but as someone who tried it a few times, I know it’s very hard, and limiting. and it takes like 30 days so probably not something you are wanting to embark on. I’m glad your Doctor seems to be very hopeful still, and that the other doctors will also weigh in. I know you must be so frustrated. This is shit. Remind me, you still have some embryos that are untested? Or have you tested all already. I just remember you had an impressive amount but can’t remember when you did go back and test them if you tested them all.
@lucyb1954 hey lady! Am planning to respond to your DM ASAP!
Homozygous MTHFR Cr677
DOR - AMH .27 High FSH (don't even know how high)
2 iui's to start - BFN
IVF 1 -3 made it do day 5! 2 5AA 1 6BB PGS results = all abnormal
IVF 2 - stimmed for 19 days. insanity. Had 5 follicles that looked mature but only 2 contained mature eggs the others were empty. Nothing made it to day 5
IVF 3 - added in HGH - 4 mature follicles (had some empties again) 3 made it to day 5/6 for PGS (held for testing with next retrieval
IVF 4 - Upped my dosage for the first time - Canceled 11 days into sims - looked like 1 follicle and we were afraid it was empty
IVF 5 - Canceled - looked like 1 follicle and we were afraid it was empty
IVF 6 - 3 mature, 2 fertalized 1 made it to day 5 and sent for PGS
Sent in IVF round 3 and 6 (4 embryos) for PGS testing and got 2 normal embryos!!! 1Boy and 1Girl. Took a little over a year to get those two embryos so demanded all sorts of test prior to attempting transfer. Did EFT, ERA and NK Cells testing.
FET#1 - Intralipid drips, Prednisone, and did a depot lupron shot before starting the FET protocol
Chemical pregnancy
FET#2 - PGS normal boy - BFN
Natural pregnancy - cycle following the FET2???? Miscarriage at 8 weeks. viability scan had shown an enlarged yolk sac so I had been warned that it was likely not chromosonally normal
DEIVF cycle - picked a donor who is willing to be open! Her cycle resulted in in 4 PGS Normal embryos
1st transfer - chemical pregnancy
2nd transfer - success, May 17 2020 due date!
Diagnosis: Mild Endo, DOR (AMH of 1.5), Poor Quality Eggs/embryos, Displaced Window of Implantation (ERA Post Receptive)
March-May 2016: 1 TI and 2 IUIs- BFN
June 2016- Laproscopy- found/removed mild endo and confirmed only 1 normal healthy ovary.
August 2016- IVF #1 with Antagonist Protocol- Cancelled (2 lead follies), converted to IUI- BFN
Oct-Nov 2016- IVF #2 with Estrogen Priming Micro Lupron Protocol, 2 eggs retrieved, day 3 transfer of 1- BFN
January 2017- New RE, IVF#3 with Estrogen Priming Antagonist Protocol, 12 eggs, 8 mature, 6 fertilized, 2 day 5 early blasts transferred (none to freeze
May 2017- Sept 2017- Starting Donor Egg process! Waiting for donor to be available... and then she is pregnant at baseline
Oct 2017- Donor #2: 25R, 22M,18F, 12 blasts frozen! Fresh transfer cancelled due to thin lining with fluid
Nov 2017- Hysterscopy to remove polyp
Dec 2017- DE FET #1 on 12/8 on 2 perfect blasts- BFN and devastated
Jan-Mar 2018- ERA #1- Post receptive by 24 hours, ERA #2 RECEPTIVE with 4 days of Progesterone
Apr 2018- DE FET cancelled for lining issues
Jun 2018- DE FET #2 of two 1AA blasts- first BFP ever! Beta 10dp5dt- 378, Beta 14dp5dt- 2840, Beta 16dp5dt- 4035, beta 18dp5dt- 10916. Due on 2/20 with one baby after a vanishing twin
Baby Born born early @ 33.5 weeks due to Pre-e
Back for # 2!
Homozygous MTHFR Cr677
DOR - AMH .27 High FSH (don't even know how high)
2 iui's to start - BFN
IVF 1 -3 made it do day 5! 2 5AA 1 6BB PGS results = all abnormal
IVF 2 - stimmed for 19 days. insanity. Had 5 follicles that looked mature but only 2 contained mature eggs the others were empty. Nothing made it to day 5
IVF 3 - added in HGH - 4 mature follicles (had some empties again) 3 made it to day 5/6 for PGS (held for testing with next retrieval
IVF 4 - Upped my dosage for the first time - Canceled 11 days into sims - looked like 1 follicle and we were afraid it was empty
IVF 5 - Canceled - looked like 1 follicle and we were afraid it was empty
IVF 6 - 3 mature, 2 fertalized 1 made it to day 5 and sent for PGS
Sent in IVF round 3 and 6 (4 embryos) for PGS testing and got 2 normal embryos!!! 1Boy and 1Girl. Took a little over a year to get those two embryos so demanded all sorts of test prior to attempting transfer. Did EFT, ERA and NK Cells testing.
FET#1 - Intralipid drips, Prednisone, and did a depot lupron shot before starting the FET protocol
Chemical pregnancy
FET#2 - PGS normal boy - BFN
Natural pregnancy - cycle following the FET2???? Miscarriage at 8 weeks. viability scan had shown an enlarged yolk sac so I had been warned that it was likely not chromosonally normal
DEIVF cycle - picked a donor who is willing to be open! Her cycle resulted in in 4 PGS Normal embryos
1st transfer - chemical pregnancy
2nd transfer - success, May 17 2020 due date!
Diagnosis: Mild Endo, DOR (AMH of 1.5), Poor Quality Eggs/embryos, Displaced Window of Implantation (ERA Post Receptive)
March-May 2016: 1 TI and 2 IUIs- BFN
June 2016- Laproscopy- found/removed mild endo and confirmed only 1 normal healthy ovary.
August 2016- IVF #1 with Antagonist Protocol- Cancelled (2 lead follies), converted to IUI- BFN
Oct-Nov 2016- IVF #2 with Estrogen Priming Micro Lupron Protocol, 2 eggs retrieved, day 3 transfer of 1- BFN
January 2017- New RE, IVF#3 with Estrogen Priming Antagonist Protocol, 12 eggs, 8 mature, 6 fertilized, 2 day 5 early blasts transferred (none to freeze
May 2017- Sept 2017- Starting Donor Egg process! Waiting for donor to be available... and then she is pregnant at baseline
Oct 2017- Donor #2: 25R, 22M,18F, 12 blasts frozen! Fresh transfer cancelled due to thin lining with fluid
Nov 2017- Hysterscopy to remove polyp
Dec 2017- DE FET #1 on 12/8 on 2 perfect blasts- BFN and devastated
Jan-Mar 2018- ERA #1- Post receptive by 24 hours, ERA #2 RECEPTIVE with 4 days of Progesterone
Apr 2018- DE FET cancelled for lining issues
Jun 2018- DE FET #2 of two 1AA blasts- first BFP ever! Beta 10dp5dt- 378, Beta 14dp5dt- 2840, Beta 16dp5dt- 4035, beta 18dp5dt- 10916. Due on 2/20 with one baby after a vanishing twin
Baby Born born early @ 33.5 weeks due to Pre-e
Back for # 2!
@JamieH2000 Great news! Is the protocol for the medication quite different from the last transfer?
Homozygous MTHFR Cr677
DOR - AMH .27 High FSH (don't even know how high)
2 iui's to start - BFN
IVF 1 -3 made it do day 5! 2 5AA 1 6BB PGS results = all abnormal
IVF 2 - stimmed for 19 days. insanity. Had 5 follicles that looked mature but only 2 contained mature eggs the others were empty. Nothing made it to day 5
IVF 3 - added in HGH - 4 mature follicles (had some empties again) 3 made it to day 5/6 for PGS (held for testing with next retrieval
IVF 4 - Upped my dosage for the first time - Canceled 11 days into sims - looked like 1 follicle and we were afraid it was empty
IVF 5 - Canceled - looked like 1 follicle and we were afraid it was empty
IVF 6 - 3 mature, 2 fertalized 1 made it to day 5 and sent for PGS
Sent in IVF round 3 and 6 (4 embryos) for PGS testing and got 2 normal embryos!!! 1Boy and 1Girl. Took a little over a year to get those two embryos so demanded all sorts of test prior to attempting transfer. Did EFT, ERA and NK Cells testing.
FET#1 - Intralipid drips, Prednisone, and did a depot lupron shot before starting the FET protocol
Chemical pregnancy
FET#2 - PGS normal boy - BFN
Natural pregnancy - cycle following the FET2???? Miscarriage at 8 weeks. viability scan had shown an enlarged yolk sac so I had been warned that it was likely not chromosonally normal
DEIVF cycle - picked a donor who is willing to be open! Her cycle resulted in in 4 PGS Normal embryos
1st transfer - chemical pregnancy
2nd transfer - success, May 17 2020 due date!
@hopefuljj- I forget- did you have a c section? My clinic is 6 months for vaginal but I think 12 for c section. Maybe 18. But hopefully not!! I would def do what worked last time. But really consider a hysterscopy and biopsy before. I have lost faith in saline’s really. And it seems endometritis is so much more common after birth. So def worth checking before trying for number two
Diagnosis: Mild Endo, DOR (AMH of 1.5), Poor Quality Eggs/embryos, Displaced Window of Implantation (ERA Post Receptive)
March-May 2016: 1 TI and 2 IUIs- BFN
June 2016- Laproscopy- found/removed mild endo and confirmed only 1 normal healthy ovary.
August 2016- IVF #1 with Antagonist Protocol- Cancelled (2 lead follies), converted to IUI- BFN
Oct-Nov 2016- IVF #2 with Estrogen Priming Micro Lupron Protocol, 2 eggs retrieved, day 3 transfer of 1- BFN
January 2017- New RE, IVF#3 with Estrogen Priming Antagonist Protocol, 12 eggs, 8 mature, 6 fertilized, 2 day 5 early blasts transferred (none to freeze
May 2017- Sept 2017- Starting Donor Egg process! Waiting for donor to be available... and then she is pregnant at baseline
Oct 2017- Donor #2: 25R, 22M,18F, 12 blasts frozen! Fresh transfer cancelled due to thin lining with fluid
Nov 2017- Hysterscopy to remove polyp
Dec 2017- DE FET #1 on 12/8 on 2 perfect blasts- BFN and devastated
Jan-Mar 2018- ERA #1- Post receptive by 24 hours, ERA #2 RECEPTIVE with 4 days of Progesterone
Apr 2018- DE FET cancelled for lining issues
Jun 2018- DE FET #2 of two 1AA blasts- first BFP ever! Beta 10dp5dt- 378, Beta 14dp5dt- 2840, Beta 16dp5dt- 4035, beta 18dp5dt- 10916. Due on 2/20 with one baby after a vanishing twin
Baby Born born early @ 33.5 weeks due to Pre-e
Back for # 2!
@JamieH2000 that is good news and reassuring that the other docs agree.
@Imajin99 we leave on Wednesday and we are flying. I just booked a facial at the spa. I'm pretty jazzed about the whole trip.
2017 - egg retrieval #1 - 3 eggs, 0 embryos appropriate for transfer; ER #2 2 eggs, 0 embryos on day 3; ER #3 1 egg 0 embryos
moved to donor egg in summer 2017; 35 eggs retrieved; 19 fertilized; 9 total embryos
Fresh transfer Dec 2017= BFP! baby boy born 8/22/18
May 2019 - surprise natural pregnancy ended in MC
Nov 2019 FET; MC at 9 weeks
May 2020 FET; BFN
July 2020 FET; CP treated with methotrexate
Oct 2020 BFP!
Take a look at my blog
Luckily, I got a second Obs opinion, bc that was playing it perhaps overly cautious? And in my case, would have significant financial ramifications, were we to keep waiting those few extra months.
<div class=" Spoiler">We were cleared and started to transfer at 12 mos, which failed, but we still had time for a few more attempts before my insurance turned over for the year, which is what I was hoping for.</div>
And I safely vbaced as 23 mos PP, FWIW. If you are going for a repeat section, it may not matter quite so much. GL!
ans I’m likely going to push for a hysterscopy and biopsy prior to transfer I think cuz I’m crazy paranoid.
@laurad75 your trip sounds like it is going to be amazing!
Homozygous MTHFR Cr677
DOR - AMH .27 High FSH (don't even know how high)
2 iui's to start - BFN
IVF 1 -3 made it do day 5! 2 5AA 1 6BB PGS results = all abnormal
IVF 2 - stimmed for 19 days. insanity. Had 5 follicles that looked mature but only 2 contained mature eggs the others were empty. Nothing made it to day 5
IVF 3 - added in HGH - 4 mature follicles (had some empties again) 3 made it to day 5/6 for PGS (held for testing with next retrieval
IVF 4 - Upped my dosage for the first time - Canceled 11 days into sims - looked like 1 follicle and we were afraid it was empty
IVF 5 - Canceled - looked like 1 follicle and we were afraid it was empty
IVF 6 - 3 mature, 2 fertalized 1 made it to day 5 and sent for PGS
Sent in IVF round 3 and 6 (4 embryos) for PGS testing and got 2 normal embryos!!! 1Boy and 1Girl. Took a little over a year to get those two embryos so demanded all sorts of test prior to attempting transfer. Did EFT, ERA and NK Cells testing.
FET#1 - Intralipid drips, Prednisone, and did a depot lupron shot before starting the FET protocol
Chemical pregnancy
FET#2 - PGS normal boy - BFN
Natural pregnancy - cycle following the FET2???? Miscarriage at 8 weeks. viability scan had shown an enlarged yolk sac so I had been warned that it was likely not chromosonally normal
DEIVF cycle - picked a donor who is willing to be open! Her cycle resulted in in 4 PGS Normal embryos
1st transfer - chemical pregnancy
2nd transfer - success, May 17 2020 due date!
ladyp0tter andreamm31 - Did you ladies have your baselines/start estrogen or do you have to get PGS results first?
3 Daughters (singleton @27yo, ID Di/Di Twins @34yo)
Protein S Deficiency (Blood Clotting Disorder), MTHFR & VIT D issue
5 MC's: Blighted Ovum-D&C @ 9wks; Natural MC @ 7wks; Blighted Ovum-D&C @ 9wks; MC boy-D&C @ 9wks & Chem PG in 2019
Tubes were tied after my Twins (and now I am old). Remarried and want to give my DH a baby!
IVF#1 OE June 2019 - ER 6/15/19, 24R, 21M, 20F, 7 6DBlasts Frozen for PGS Testing,
RESULTS of PGS 4 abnormal girls, 2 abnormal boys, 1 indeterminate girl
FET#1 OE August 23, 2019 (transferring 1 indeterminate girl & 1 abnormal boy) - BFN
IVF#2 November 15, 2019 - ER 9R, 9M, 6F, 2 5dBlasts (fresh transfer) and 1 6DBlast frozen for PGS Testing,
FRESH Transfer: November 20, 2019, 2 5-day blasts transferred!!
BFP 8dp5dt on 11/27 - 12/2 on FRER, BETA #1 12/2 - 11.93. BETA #2 12/4: 4.41 ~CHEMICAL PG
******************Starting Donor Process
June 2020: Egg Donor Cycle and Fresh Transfer of 1 embryo in Czech Republic - CANCELLED DUE TO COVID19
October 2020. Split Cycle at UFC with a friend (Andrea) I met on the Bump who was also supposed to go to Prague too
DE Retrieval 9/26/2020, 26R, 24M, 12 split Cycle, 9 Fertilized + 1 "questionable", PRAYING FOR AT LEAST 5 BLASTS
10/1/2020: 4 5DBlasts (AA, BB, BC, BC), 10/2/2020: 3 6DBlasts (BB, BB, BC) FOR A TOTAL OF: 7 BLASTS!! THANK YOU GOD!!
PGS RESULTS: 5 NORMALS! DAY 5: AA BOY, BB GIRL, BC BOY / DAY 6: BB GIRL, BC GIRL
DE FET October 29, 2020 - CANCELED DUE TO FLUID IN LINING
DE FET November 16th, 2020 (transferring an PGS normal Hatching AA Boy)
Diagnosis: Mild Endo, DOR (AMH of 1.5), Poor Quality Eggs/embryos, Displaced Window of Implantation (ERA Post Receptive)
March-May 2016: 1 TI and 2 IUIs- BFN
June 2016- Laproscopy- found/removed mild endo and confirmed only 1 normal healthy ovary.
August 2016- IVF #1 with Antagonist Protocol- Cancelled (2 lead follies), converted to IUI- BFN
Oct-Nov 2016- IVF #2 with Estrogen Priming Micro Lupron Protocol, 2 eggs retrieved, day 3 transfer of 1- BFN
January 2017- New RE, IVF#3 with Estrogen Priming Antagonist Protocol, 12 eggs, 8 mature, 6 fertilized, 2 day 5 early blasts transferred (none to freeze
May 2017- Sept 2017- Starting Donor Egg process! Waiting for donor to be available... and then she is pregnant at baseline
Oct 2017- Donor #2: 25R, 22M,18F, 12 blasts frozen! Fresh transfer cancelled due to thin lining with fluid
Nov 2017- Hysterscopy to remove polyp
Dec 2017- DE FET #1 on 12/8 on 2 perfect blasts- BFN and devastated
Jan-Mar 2018- ERA #1- Post receptive by 24 hours, ERA #2 RECEPTIVE with 4 days of Progesterone
Apr 2018- DE FET cancelled for lining issues
Jun 2018- DE FET #2 of two 1AA blasts- first BFP ever! Beta 10dp5dt- 378, Beta 14dp5dt- 2840, Beta 16dp5dt- 4035, beta 18dp5dt- 10916. Due on 2/20 with one baby after a vanishing twin
Baby Born born early @ 33.5 weeks due to Pre-e
Back for # 2!
Homozygous MTHFR Cr677
DOR - AMH .27 High FSH (don't even know how high)
2 iui's to start - BFN
IVF 1 -3 made it do day 5! 2 5AA 1 6BB PGS results = all abnormal
IVF 2 - stimmed for 19 days. insanity. Had 5 follicles that looked mature but only 2 contained mature eggs the others were empty. Nothing made it to day 5
IVF 3 - added in HGH - 4 mature follicles (had some empties again) 3 made it to day 5/6 for PGS (held for testing with next retrieval
IVF 4 - Upped my dosage for the first time - Canceled 11 days into sims - looked like 1 follicle and we were afraid it was empty
IVF 5 - Canceled - looked like 1 follicle and we were afraid it was empty
IVF 6 - 3 mature, 2 fertalized 1 made it to day 5 and sent for PGS
Sent in IVF round 3 and 6 (4 embryos) for PGS testing and got 2 normal embryos!!! 1Boy and 1Girl. Took a little over a year to get those two embryos so demanded all sorts of test prior to attempting transfer. Did EFT, ERA and NK Cells testing.
FET#1 - Intralipid drips, Prednisone, and did a depot lupron shot before starting the FET protocol
Chemical pregnancy
FET#2 - PGS normal boy - BFN
Natural pregnancy - cycle following the FET2???? Miscarriage at 8 weeks. viability scan had shown an enlarged yolk sac so I had been warned that it was likely not chromosonally normal
DEIVF cycle - picked a donor who is willing to be open! Her cycle resulted in in 4 PGS Normal embryos
1st transfer - chemical pregnancy
2nd transfer - success, May 17 2020 due date!
@JamieH2000. Dang girl....I read back and you have so much going on! Im sorry you have so much uncertainty. I think the steroids are really going to be helpful. It sounds like you have a lot of histamine in your system with your allergies like that and the tissue. I wonder if an antihistamine would also be helpful for you. Like Claritin or Allegra ....which ever one is ok during pregnancy (I think they both are). There are histamine containing foods you should stay away from too....I would google it, but I know Kombucha is high in histamine. This will help decrease inflammation too. I think you gotta just go with it. you did all the antibiotics, and it sounds like your RE has a good plan. I would do it too! 4.5 weeks will be here so soon!
@hopefuljj That is so exciting you are starting to think about #2!
AFM:
We got 6 PGS normal embryos, 3 boys and 3 girls from 10 Embryos! We had one that was untested because there wasn't enough DNA, but its also my day 6 BC, so I will probably not use that one unless I was desperate. Going to transfer an AB GIRL! Really excited and so happy with these results. I just know my babies now EXIST on this earth. Its so crazy and miraculous. I feel so much positive energy and calmness around all of this which is usually my sign that things are just going to work out and bring me my babies! Im obviously so thrilled that Gina got so many too. Man, we are so freaking blessed with the donor they suggested for us. Transfer is in 2.5 weeks!
39 years old DH 41. Sperm looks great. We live in San Diego
Me: ****TW loss mentioned***
MTHFR Homozygous 677TT (dx 2016)
hypothyroid
8/2018 Off birth control
11/29/2018 CP
2/10/2019. CP
3/8/2019 Saw fertility doctor, AFC 5, labs drawn
3/14/2019 Pregnant
4/18/2019 9 week ultrasound MM , stopped growing at 6 weeks, no HB. D&C
5/2/2019 Return to fertility doctor, labs show AMH 0.27. Diminished Ovarian Reserve
1st of 3 Egg retrievals planned tentatively for July
6/29/2019 started Antagonist Protocol
7/12/2019 First egg retrieval, only retrieved one egg and fell apart immediately, poor quality.
8/7/2019. Second cycle (follicular antagonist) canceled on day 5 of stims when a very large lead follicle grew out of nowhere.
11/8/2019. Second Egg retrieval with Lupron Flare Protocol. 2 eggs retrieved, fertilized with ICSI but no reaction occurred at all. Told I will never have my own babies with my eggs.
12/20/2019 ERA - pre-receptive. Needed 24 hours more of progesterone
2/2020 CP
3/2/2020 Egg donor cycle in Prague at Unica Clinic, 2 AA embryos, 1 transfer, 1 on ice. BFN. Due to pandemic, we could not return to Prague and will abandon our remaining embryo.
4/20/2020. BFP trying on our own!
06/04/2020 After HBs at 7 and 9 weeks, MM at 10 weeks 3 days. D&C, Hemorrhaged out 1 liter of blood from uterine artery rupture during procedure. Spent 1 night in the hospital with a balloon tamponade in my uterus. Baby was mosaic Trisomy 21.
8/2020. Moving forward with Donor Egg cycle at Utah Fertility Center and sharing a cycle with ladypOtter (Gina) I met on the Bump who was also supposed to go to Prague but couldn't.
9/26/2020 Donor retrieval of 26 eggs, 24 mature. Split cycle so I have 12 eggs with all 12 fertilizing. 6 PGS normal 3 boys, 3 girls
10/29/2020 Transfer day of girl donor egg embryo. BFP! First HCG 92.9. Then inappropriate rise, plateau and falling. Possibly ectopic pregnancy. ER visit with diagnosis of "pregnancy location unknown". CP
1/19/2021 Embryos shipped from Utah to my local clinic, starting prednisone for anti-histamine protocol.
2/26/2021 FET girl embryo BFP. Betas 62, 139, 386! HB at 6 weeks, then baby stopped growing at 8 week check up with weak HB measuring 6 weeks 4 days. MM at 9 weeks. D&C 4/15/21
7/13/2021 FET boy and girl embryos. First beta 10dp5dt 177, 14dp5dt 1631, 16dp5dt 6809. Pregnant with Identical triplets. At 9 weeks, Baby C no longer had a heart beat. Identical Twin Girls. Pregnancy complicated by TRAP Sequence with baby C an Acardiac fetus still receiving blood flow being pumped to it by other girls. Referred to UCSF at 18 weeks for consultation. No intervention needed at this time
2/18/22 After a failed NST, at 34 weeks 1 day, Charlotte born 4lb 4oz and Lily born 4lbs 10 oz. Our hearts are complete. Baby girls in NICU to grow and learn to eat.
The trip sounds amazing and the perfect way to keep your mind occupied! Although if you do test and get a BFP, it will sorta suck that you can't drink any wine! I actually got my first natural BFP three days before our annual trip to France and so I couldn't eat anything unpasteurized (cheese, yogurts, etc) or any wine (which is so hard in France!). I miss traveling soooo much; it is always filled with so many surprises and exciting times (plus relaxing too!). DH is pretty strict on covid measures so we haven't gone anywhere in awhile. We're already planning our next trip (to Disney, it's near to us and kid friendly) which we will hopefully be able to do this upcoming spring (fx for having some kind of vaccine out by then). Of course, the idea of Disney while heavily pregnant doesn't sound much fun to me (if we transfer beforehand and are fortunate, of course).
@JamieH2000
My RE actually has a steroid course and antibiotic course prior to transfer just to be on the safe side -- did yours do that before? There are some old wives' tales that anti-histamines can also help with conception (some ladies claim taking antihistamines during their cycle was the reason for their success). If you don't mind the side effects, benadryl is considered safe in pregnancy (and often used for sleep issues), so maybe a tab before bed might be some extra security if you want it?
@andreamm31
Awesome numbers! That your babies exist on this planet now is such a good feeling. I was really down during my IVF cycle so I didn't have many moments of excitement like that, but I hope that you, like me, will look back next year while you're holding your baby on this same day and think of this time. It's super surreal how those little embies turn into our little girls and boys.
@ladyp0tter
Great results and a hatching blast is the best!! Mine were hatching after they thawed and my embryologist was thrilled, saying that's the best possible sign. Fx for a little boy for you!
AFM we're hopefully going to get a closing date on our refinance in the next week or so since our docs are now in underwriting -- we're refinancing the mortgage and rolling our HELOC into it, and getting a cash out for our roof replacement and fertility stuff - so we're possibly looking at a November start unless I decide to wait until January after the holidays. I pulled a few journal studies on BCP and low AMH for my RE so we can discuss that; his major sticking point is that I've been super irregular and my AFC and FSH are still OK. With an AMH of 0.62 last time and doing a mini-stim, we got 10 eggs (9 mature) so he doesn't feel there's any reason to be overly concerned about suppression. He wants me to focus on quality rather than quantity so I've already started taking some supplements (vitamin d, coq10, DHEA, etc) and taking out some of the processed garbage out of my diet. I also have to get off one of the meds I take for anxiety (started it postpartum) so I've been working with my therapist a bunch on methods to cope if I do have a rebound after going off it. Last time I tried to drop it, I got a nasty rebound of anxiety/depression.
Summer 2015 - no BFP yet, labs normal, referred to RE
Fall 2015 - Summer 2016 - Further testing all normal. 3 IUI's -- BFN. Recommended move to IVF. Planned cycle for fall 2016.
September 2016 - Surprise natural BFP. MMC @ 8 weeks. RE expressed confidence that we just needed the 'right' embryo.
Fall 2016 - Spring 2017 -- Break from TTC
June 2017 - Started IVF; egg retrieval for freeze all cycle. 9 mature eggs retrieved, 5 fertilized. 2 4BB embies on ice.
August 2017 - FET transfer both embies. BFP. Twin pregnancy confirmed by ultrasound. EDD 4/28/18
September 2017 - Twin B stopped developing; Twin A doing perfectly! Graduated from RE @ 10 weeks
March 2018 - Baby Girl born via C/S due to pre-eclampsia -- strong and healthy!
TTC #2
January/Feb 2021 - Freeze-all IVF cycle
March 2021 - FET of 1 PGS normal female embryo. BFP! Beta #1 156, #2 472, #3 1241, #4 5268 EDD 12/5/21 - Christmas baby!
"When all is lost then all is found."
@mbradfo2- yup my procotol has always had the steroid and antiobtioc so hopefully the reason for the last chemical was the polyp and scar tissue... I think it’s good to discuss the studies with your RE. If you are flexible with timing, it may be ok to wait for your natural cycle... has it been irregular since the birth? It would suggest something is off hormonally since I don’t think you are heading into menopause or anything with your numbers... I guess you could always do BC and if the baseline showed reduced AFC or they didn’t respond , then you could just cancel. But it is such a disappointing thing to go thru
Diagnosis: Mild Endo, DOR (AMH of 1.5), Poor Quality Eggs/embryos, Displaced Window of Implantation (ERA Post Receptive)
March-May 2016: 1 TI and 2 IUIs- BFN
June 2016- Laproscopy- found/removed mild endo and confirmed only 1 normal healthy ovary.
August 2016- IVF #1 with Antagonist Protocol- Cancelled (2 lead follies), converted to IUI- BFN
Oct-Nov 2016- IVF #2 with Estrogen Priming Micro Lupron Protocol, 2 eggs retrieved, day 3 transfer of 1- BFN
January 2017- New RE, IVF#3 with Estrogen Priming Antagonist Protocol, 12 eggs, 8 mature, 6 fertilized, 2 day 5 early blasts transferred (none to freeze
May 2017- Sept 2017- Starting Donor Egg process! Waiting for donor to be available... and then she is pregnant at baseline
Oct 2017- Donor #2: 25R, 22M,18F, 12 blasts frozen! Fresh transfer cancelled due to thin lining with fluid
Nov 2017- Hysterscopy to remove polyp
Dec 2017- DE FET #1 on 12/8 on 2 perfect blasts- BFN and devastated
Jan-Mar 2018- ERA #1- Post receptive by 24 hours, ERA #2 RECEPTIVE with 4 days of Progesterone
Apr 2018- DE FET cancelled for lining issues
Jun 2018- DE FET #2 of two 1AA blasts- first BFP ever! Beta 10dp5dt- 378, Beta 14dp5dt- 2840, Beta 16dp5dt- 4035, beta 18dp5dt- 10916. Due on 2/20 with one baby after a vanishing twin
Baby Born born early @ 33.5 weeks due to Pre-e
Back for # 2!
Thanks gang. Ugh the wait sucks and I'm trying so hard to stay positive and think positive but then my mind gets the best of me and I start to spiral. We leave first thing in the morning and I can't wait.
2017 - egg retrieval #1 - 3 eggs, 0 embryos appropriate for transfer; ER #2 2 eggs, 0 embryos on day 3; ER #3 1 egg 0 embryos
moved to donor egg in summer 2017; 35 eggs retrieved; 19 fertilized; 9 total embryos
Fresh transfer Dec 2017= BFP! baby boy born 8/22/18
May 2019 - surprise natural pregnancy ended in MC
Nov 2019 FET; MC at 9 weeks
May 2020 FET; BFN
July 2020 FET; CP treated with methotrexate
Oct 2020 BFP!
Take a look at my blog
2017 - egg retrieval #1 - 3 eggs, 0 embryos appropriate for transfer; ER #2 2 eggs, 0 embryos on day 3; ER #3 1 egg 0 embryos
moved to donor egg in summer 2017; 35 eggs retrieved; 19 fertilized; 9 total embryos
Fresh transfer Dec 2017= BFP! baby boy born 8/22/18
May 2019 - surprise natural pregnancy ended in MC
Nov 2019 FET; MC at 9 weeks
May 2020 FET; BFN
July 2020 FET; CP treated with methotrexate
Oct 2020 BFP!
Take a look at my blog
Just make sure the meds all are labelled with the doctor's prescription and I would ask for a note from your RE's office listing what medications were prescribed and that they are administered by injection, just to be on the safe side. Depending on the TSA agent, it will either be smooth or a pain. Unused needles and syringes for prescribed medication are allowed through security as long as they are accompanied by the medicine.
Summer 2015 - no BFP yet, labs normal, referred to RE
Fall 2015 - Summer 2016 - Further testing all normal. 3 IUI's -- BFN. Recommended move to IVF. Planned cycle for fall 2016.
September 2016 - Surprise natural BFP. MMC @ 8 weeks. RE expressed confidence that we just needed the 'right' embryo.
Fall 2016 - Spring 2017 -- Break from TTC
June 2017 - Started IVF; egg retrieval for freeze all cycle. 9 mature eggs retrieved, 5 fertilized. 2 4BB embies on ice.
August 2017 - FET transfer both embies. BFP. Twin pregnancy confirmed by ultrasound. EDD 4/28/18
September 2017 - Twin B stopped developing; Twin A doing perfectly! Graduated from RE @ 10 weeks
March 2018 - Baby Girl born via C/S due to pre-eclampsia -- strong and healthy!
TTC #2
January/Feb 2021 - Freeze-all IVF cycle
March 2021 - FET of 1 PGS normal female embryo. BFP! Beta #1 156, #2 472, #3 1241, #4 5268 EDD 12/5/21 - Christmas baby!
"When all is lost then all is found."
My story in signature spoiler. Children mentioned.
I don't produce FSH, so no natural menstrual cycle. DH has reduced morphology.
Summer 2014 IUI (with first husband): cancelled after almost a month of stims due to too many follicles
Time off to divorce, get back on my feet, find a new hubby and get married again 💑
March 2017 IVF#1: ~70 follicles, 13R, 10M, 7F, 3B = 2 PGS Normal (both XY) - no transfer due to ohss
Sept 2017 FET#1: BFP, Beta#1 (10dpt) - 253, Beta#2 (12dpt) - 528, DS born 05/31/2018 👨👩👦
Dec 2019 FET#2: BFN
Changed clinic, planning March 2020 IVF#2 - postponed due to the pandemic
April 2020 IVF #2: ~30 follicles, 24R, 12M, 8F, 4B = 2XY & 2XX, all normal
Sept 2020 FET#3: one XX embryo, BFP, Beta#1 (9dpt) - 161, Beta#2 (11dpt) - 519, Beta#3 (19dpt) - 7174, Due date 05/30/2021
DD born 05/23/2021 👨👩👧👦 - My family is now complete
@JamieH2000 the antihistamine protocol that’s was maybe what andreamm31 was referencing requires you take Benadryl but also Pepcid on a specific schedule. So I don’t think a regular antihistamine is as effective, just an FYI!!
Homozygous MTHFR Cr677
DOR - AMH .27 High FSH (don't even know how high)
2 iui's to start - BFN
IVF 1 -3 made it do day 5! 2 5AA 1 6BB PGS results = all abnormal
IVF 2 - stimmed for 19 days. insanity. Had 5 follicles that looked mature but only 2 contained mature eggs the others were empty. Nothing made it to day 5
IVF 3 - added in HGH - 4 mature follicles (had some empties again) 3 made it to day 5/6 for PGS (held for testing with next retrieval
IVF 4 - Upped my dosage for the first time - Canceled 11 days into sims - looked like 1 follicle and we were afraid it was empty
IVF 5 - Canceled - looked like 1 follicle and we were afraid it was empty
IVF 6 - 3 mature, 2 fertalized 1 made it to day 5 and sent for PGS
Sent in IVF round 3 and 6 (4 embryos) for PGS testing and got 2 normal embryos!!! 1Boy and 1Girl. Took a little over a year to get those two embryos so demanded all sorts of test prior to attempting transfer. Did EFT, ERA and NK Cells testing.
FET#1 - Intralipid drips, Prednisone, and did a depot lupron shot before starting the FET protocol
Chemical pregnancy
FET#2 - PGS normal boy - BFN
Natural pregnancy - cycle following the FET2???? Miscarriage at 8 weeks. viability scan had shown an enlarged yolk sac so I had been warned that it was likely not chromosonally normal
DEIVF cycle - picked a donor who is willing to be open! Her cycle resulted in in 4 PGS Normal embryos
1st transfer - chemical pregnancy
2nd transfer - success, May 17 2020 due date!
2017 - egg retrieval #1 - 3 eggs, 0 embryos appropriate for transfer; ER #2 2 eggs, 0 embryos on day 3; ER #3 1 egg 0 embryos
moved to donor egg in summer 2017; 35 eggs retrieved; 19 fertilized; 9 total embryos
Fresh transfer Dec 2017= BFP! baby boy born 8/22/18
May 2019 - surprise natural pregnancy ended in MC
Nov 2019 FET; MC at 9 weeks
May 2020 FET; BFN
July 2020 FET; CP treated with methotrexate
Oct 2020 BFP!
Take a look at my blog