This is a place for those of us who have already started TTC, but have started infertility testing and/or treatments. You can express your thoughts, feelings, and frustrations on infertility. TTC can be a long journey naturally, then add in the difficulties associated with infertility, and it becomes a whole new ballgame. The road to infertility can be lonely, frustrating, and complicated, so let's make this a place where we can vent, ask questions, and support one another. Feel free to resurrect this thread at any point in the week if you have something to say. Treat this as an ongoing conversation.
Diagnosis (if you've been):
Status (TI/ICI/IUI/IVF/FET/benched):
What are you doing this cycle? (Testing? Treatment?):
How are things going?:
Any questions?:
GTKY: Do you play the lotto? What would you do if you won this record breaking Power Ball?
Re: IF Testing & Treatment w/o 11/7
Diagnosis (if you've been): PCOS
Status (TI/ICI/IUI/IVF/FET/benched): TI
What are you doing this cycle? (Testing? Treatment?): Gonal-F, ovidrel, Endometrin
How are things going?: So far so good. Triggered last night and will be starting Endometrin on Thursday. I’m a little anxious because DH got an ear infection over the weekend and is on antibiotics now. Dr Google indicated it could negatively impact sperm count and motility. Guess we’ll have to see.
Any questions?: Any tips/info you wish you’d known before starting Endometrin?
GTKY: Do you play the lotto? What would you do if you won this record breaking Power Ball? I don’t typically play the lotto. If I won, I’d pay off all my debt and with the remaining $20, go out to lunch 😂. In all seriousness though, pay off debt for myself and all of my siblings, take a long vacation, fix up/renovate my house, and invest/save for retirement.
Diagnosis (if you've been): retired ovaries, LPD
Status (TI/ICI/IUI/IVF/FET/benched): TI while waiting for IVF
What are you doing this cycle? (Testing? Treatment?): Just HIO all weekend. My H and I had a really fun weekend..wink wink..
. But this morning my H said "no more! I can't again today" haha which is fine since O was yesterday.
How are things going?: I'm happy that last week is over. It was really rough and I'm just trying to focus on the happy things in my life.
Any questions?: Last night while H and I were DTD, I started cramping really badly. I'm not sure if it was ovulation cramping or if my body was just waving it's white flag...my ovaries are still a little sore today, so maybe O pain? Has that happened to anyone before?
GTKY: Do you play the lotto? What would you do if you won this record breaking Power Ball? oh my goodness. I don't normally play, but I bought a ticket yesterday. First thing would be is go on a loooooong vacation somewhere. Then buy some real estate in really cool places. I would pay off the houses of our families, and then would pay for the best Egg donor plan there is.TTC: Sept 2016-Oct 2017
BFP Oct 2017. DD born July 2018.
TTC: March 2020. BFP March 2020
Due date was Nov 2020
DS born Sept 2020. DS passed away Nov 2020 due to prematurity and birth trauma.
TTC: March 2021
IUI #1 Nov 2021, BFN
IUI #2 Dec 2021 BFP. MC Jan 2022
IUI #3 Aug 2022 BFN
IUI #4 Sept 2022 BFN
AMH test came back at .081. Was going to move on to IVF with DE, but have decided not to. Will be leaving it up to the universe now.
@gingermama29 yeah.... You're going to want more than a basic pantiliner. I think these are the ones I bought because it's a lot when it leaks out. They're about as thick as a pad but it's a small price to pay to not feel grossly wet down there.
Dx: low morph (1%), ANA positive, low decidualization score, high TSH and testosterone, histone antibodies
IUI #1-3 | all BFN
IVF #1 | 6.11.19 | 24R, 17M, 15F, 6B, PGT-A tested - 5 normal, 3 girls & 2 boys
FET #1 | 9.10.19 | BFN "I know you, but we've never met. I'm with you, but I don't know your name"
RPL, Receptiva, & ERA testing | all normal/negative, recommended going on gluten and dairy free diet for next FET
FET #2 | 3.31.20 | Opted to cancelled due to pandemic, continued diet and tried naturally over the summer
2nd Opinion with another RE | 8.20.20 | Not immune to measles (received 1 dose); SA results similar to 2 years ago; decided to move forward with FET #2 redo at start of next cycle
Surprise natural BFP! | 9.22.20 | MC 10.23.20 at 8 weeks
TTCAL naturally | starting 11.22.20
Initial consultation with Reproductive Immunologist | 9.14.21
Decidualization score biopsy | 10.1.21 | abnormal - low score of 1; endometrial scratch recommended and progesterone supplementation
Saline sono | 10.15.21 | normal
Bloodwork | 10.21.21 | high TSH, high testosterone, positive for anti-nuclear antibodies and histone antibodies, high protein S, multiple genetic mutations
BFP! | 11.3.21 | EDD 7.14.22
DS born 7.19.22 after induction
TTC #2 begins 6.2023
Consultation with RI | 6.6.23
Saline sono, endometritis biopsy, skin & eye check | all normal
Labs | high TSH, Factor XIII mutation, high %CD56
Follow up | 8.8.23 | prescribed metformin, prednisone, plaquenil, and levothyroxine
Repeat labs after 3 weeks on meds
Follow up | 11.9.23 | Green light!, increase in prednisone, added lovenox
Repeat labs in 8 weeks
Follow up | 1.16.24 | Green light continues
TTC ended due to filing divorce
**New relationship starting May 2024**
Surprise BFP!! | 9.7.25 | EDD 5.11.26
@bearmomma1 yess girl, I love that you had a fun weekend HIO. That kind of intimacy that isn't on some schedule and is actually enjoyable can feel so foreign when you're TTC so I'm all for a little sugar and spice when the mood strikes. // Not sure about the cramping Q, could've been just a very strong ovulation, or like you say, maybe just a little too much excitement for Queen V.
@anniemarie887 from last week, so very sorry your CE is so persistent. I haven't done the Alice or ERA, here in Ontario we can get the endometrial biopsy covered by our public health insurance plan but it only tests for the presence of the CD138 inflammatory markers, not the specific strains. I think the Alice is the same idea but they test for the most common strains. The ERA is the receptivity test, so that one does need to be done at a specific time in your cycle because the thought is that it'll mimic the exact time of implantation for IVF purposes, but the test is falling out of favor these days because the research was heavily biased at the time and hasn't been proven to be as effective as they claim. Now the EMMA is the other test offered by Igenomix as part of their EndomeTRIO testing, that one tests the microbiome. I haven't done that one either because my RE doesn't believe in it but I did take some vaginal probiotics for a little while just to hedge my bets. I'll start it back up post-op once I've been cleared.
@optimistgardener to answer your Q from last week, it's an abdominal myomectomy so not laparascopic. He said the incision should hopefully be only 2-3", which still sounds painful. Ugh. I'm guessing I should expect to be off work for at least a week, then maybe I'll WFH for a few days the following week too.
Diagnosis (if you've been): PCOS, RPL/RIF, MFI, and soon to be sans-Fibroid
Status (TI/ICI/IUI/IVF/FET/benched): Technically benched?
What are you doing this cycle? (Testing? Treatment?): Less than 4 weeks away from my myomectomy. Nerves have started to set in.
How are things going?: On the one hand I've been enjoying this time off from active treatment, eating what I want, not feeling guilty about the occasional drink, not having to worry about timing or being at the clinic, not being on so many meds (!!!)... but it weighs heavily on my heart to know that we're still so far away from our dream. Not being able to transfer until April means definitely no baby in 2023, meanwhile it feels like everyone around me is neck deep in all things babies and children. Now I have a new fear that DH's baby cousin will also get KU before us since they're getting married next summer. (she's not really a baby anymore, but she's the youngest in the family and was the reason DH wanted kids because he was in high school by the time she was born).
Any questions?: NATM
GTKY: Do you play the lotto? What would you do if you won this record breaking Power Ball? No I don't, and being Canadian the Power Ball phenomenon is just mind-blowing to me, but that doesn't mean we don't still dream of winning the lotto. Love all the answers so far. Mine would be pay off debt, donate to my favourite charities, buy a vacation property in Hawaii, encourage DH to quit his job... all amazing things, but it's not lost on me that no amount of money could buy me a baby.
TTC History:
Me: 36 MH: 39, TTC since Dec 2017
Aug '18: PCOS dx
Nov '18: MH SA - 19mil
Dec '18-Mar '19: Letrozole + TI - all BFN
Apr '19: Letrozole + TI, - BFN. Repeat SA (27mil) & DNA fragmentation test (17%)
Aug '19: Letrozole + HCG trigger + IUI + prog supp - BFN (MH: 16mil)
Sep '19: 2nd IUI, same protocol - BFN (MH: 16mil)
Dec '19: IVF #1 w/ICSI, PGT. 5 retrieved, 4 fertilized, 3 blasts, 3 PGT-A normal.
Mar '20: FET #1, perfect 5AA blast transferred. BFN.
Sept '20: FET #2, 5BB tsf. 9/18/20 BFP!! EDD: 5/27/21. MMC 11w
Feb ‘21: FET #3, last 6BB blast transferred. BFP, EDD 11/2/21. MC 5w3d.
May '21: IVF #2 w/ICSI, PGT. 8R, 7M, 6F, 6 blasts - 3AB, 3AB, 3BB, 4BB, 5BB, 6BA. Fresh tsf 5/13/21 - BFN.
June '21: PGT-A results = 3 abnormal, 1 low level mosaic. Referred to new REI, had consult with 2nd RE in between.
Sept '21: RPL, immune testing normal
Oct '21: IVF #3 w/IMSI, PGT. 33R, 26M, 23F, 9 blasts (7 day 6, 2 day 7). PGT-A = 5 normal, 1 mosaic
Dec '21: Positive for endometritis, RX Flagyl & Keflex
Jan '22: FET #5 - Kitchen sink immune/RIF protocol incl. PRP, intralipids, prednisone, medrol, nivestym, fragmin - CP
Feb '22: FET #6 - Kitchen sink immune/RIF protocol w/higher doses of pred & fragmin - BFN
Mar '22: Mock cycle for ERA - cancelled, repeat endometrial biopsy instead. Still positive for endometritis. RX ciprofloxacin & amoxicillin.
Apr '22: IVF #4 w/IMSI, PGT. 28R, 23M, 16F, 11 blasts. PGT-A = 6 normal.
June '22: FET #7 - Microdose lupron downreg w/kitchen sink immune/RIF protocol - double embryo transfer. BFN.
July '22: FET #8 - Mini stim w/Puregon + trigger, kitchen sink immune/RIF protocol. BFN.
Sep '22: Taking a break
Dec '22: Attempted abdominal myomectomy, fibroid too close to cervix and major blood vessels. Wasn't removed.
Feb '23: FET #9 - Modified natural w/baby asp, HCG trigger, PIO, PRP, Medrol, HCG wash, embryo glue - BFP!! EDD 11/11/23
Diagnosis (if you've been): uncooperative uterus/RPL, chronic endometritis that won't quit
Status (TI/ICI/IUI/IVF/FET/benched): benched
What are you doing this cycle? (Testing? Treatment?): Alice test - 2-3 weeks for results
How are things going?: meh, grumpy. i have a super hectic next 48 hours, then i'm off to disney world with a friend until sunday. but of course now a hurricane is looming.
Any questions?: natm
GTKY: Do you play the lotto? What would you do if you won this record breaking Power Ball? well, firstly mortage and car payments would be gone! then some hefty charitable donations, hire more employees so i could totally check out of my office and have someone else run it, and take an amazing vacation.
@bearmomma1 get it girrrrrrrrl, glad you had a good weekend. you deserve it!
@gingermama29 adding more - are you doing it 1x or 2x day? if you can do it at night before bed it is less messy... when i am able to ttgp again my RE wants me doing morning and night though.
@kiki047 yea, so when actually seeing the RE today it was Alice. i think her receptionist just went off the broad spectrum of what they offer. and yes, my biopsies so far are the CD138 stain, so just a generic testing. she indicated that this could just be showing inflammation and maybe not truly an infection, that the inflammation could be in part due to the incessant prodding my poor uterus has been subjected to? at least i think that's how i understood what she said. it was 75 here today, her office was sweltering, and i always get anticipatory anxiety going into these so i was just like uh huh, sure, get it over with and get me out of here. just giving you a big hug, i truly know how hard it is grappling with the passage of time.
Just sending all the love to you ladies!
@anniemarie887 I hope you're test results come back good, or at least with some answers!
@kiki047 I hope your surgery goes well!
@ everyone- just sending all the positive vibes!
@inthewoods23 thank you friend
@kiki047 I’m glad you’ve been making the most of this time off of treatment but I definitely empathize with how you’re feeling.
TTC: Sept 2016-Oct 2017
BFP Oct 2017. DD born July 2018.
TTC: March 2020. BFP March 2020
Due date was Nov 2020
DS born Sept 2020. DS passed away Nov 2020 due to prematurity and birth trauma.
TTC: March 2021
IUI #1 Nov 2021, BFN
IUI #2 Dec 2021 BFP. MC Jan 2022
IUI #3 Aug 2022 BFN
IUI #4 Sept 2022 BFN
AMH test came back at .081. Was going to move on to IVF with DE, but have decided not to. Will be leaving it up to the universe now.
TTC: Sept 2016-Oct 2017
BFP Oct 2017. DD born July 2018.
TTC: March 2020. BFP March 2020
Due date was Nov 2020
DS born Sept 2020. DS passed away Nov 2020 due to prematurity and birth trauma.
TTC: March 2021
IUI #1 Nov 2021, BFN
IUI #2 Dec 2021 BFP. MC Jan 2022
IUI #3 Aug 2022 BFN
IUI #4 Sept 2022 BFN
AMH test came back at .081. Was going to move on to IVF with DE, but have decided not to. Will be leaving it up to the universe now.
Diagnosis (if you've been): elderly ovary on crutches
Status (TI/ICI/IUI/IVF/FET/benched): waiting for FET
What are you doing this cycle? (Testing? Treatment?): just waiting
How are things going?: i'm sorry i've been MIA lately. i'm just waiting around for things to start getting more interesting with my IVF stuff. My next RE appointment isn't until early December, when I'll throw a full kitchen sink worth of questions at him and such. Meanwhile, I find myself in the weird situation of maybe? kind of? thinking about dating? a good friend? It's early days so who knows and he knows all about my IVF journey because i've been talking about it all the way through but it's a bit of a mindf**** to be like, aiming to get myself knocked up w/ all the science i can muster, but also trying to figure out what's happening on the friend/romance front. it's very welcome, because i have been more or less single for a while. just weird. anyway.
Any questions?: not really.
GTKY: Do you play the lotto? What would you do if you won this record breaking Power Ball? golly. well i'm lucky enough not to be in debt myself, so i'd probably get all my friends and family out of debt, put down payments on houses for a couple of them, and then i'd consider putting together an endowment for the floundering university i work at. and buy a bunch of fancy blazers and shoes while i figure out how to squander whatever is left.Oct '21 somewhat improved AMH (.51) and significantly improved FSH (8.9). Maybe it's all the pills I swallow.
Dec -21, standard antagonist. 225menupur/225gonal-f/cetrotide/5000u trigger, AFC 5; 11 days of stims. retrieval yields 5, 4M, 2 reach day-6 blast (4AB & 4BB). 1 low-level mosaic (chr. 3 deletion), 1 complex abnormal.
Feb '22 FET (low-level mosaic): CP.
May '22 egg retrieval, lupron flare protocol. HGH priming for 1 month before stims; md lupron 20/20u daily; menopur 225, follistim 225, 10k trigger after 8 days of stims; AFC 10; 13 retrieved; 10 mature; 8 fertilized. All frozen at 2PN for later thaw, grow, and biopsy.
July '22 egg retrieval same protocol: 9 days of stims; AFC 8; 10 retrieved, 8 mature, 4 fertilized and frozen.
Sept '22 ER same protocol: AFC 10; 12 retrieved, 11 mature, 11 fertilized.
From the 3 retrievals, 7 survived to day 5-6 blastocyst, from which I have 2 normal embryos!
Jan 20, Fully medicated FET, baby aspirin, dexamethasone, acupuncture, and as much woo as I can stand (which isn't very much). BFN.
July 23, Natural FET + baby aspirin. BFN.
@optimistgardener That sounds exciting to be considering a romantic interest! You fertility journey seems like it has been very tough (as they all are) and a little romance can be fun! Good luck moving forward with that! And good luck with your upcoming appointment and FET!