@acleverusername thanks for the info! My RE's opinion on both supplements was that they could potentially help, and that neither was particularly risky. This was before my day 3 labs last month, and I don't appear to have DOR so maybe they're less important. But on the other hand, I am "unexplained" so I'm willing to try any little factor that might help with egg quality! Especially taking clomid to get more of them! I also read that especially CoQ10 can take 6-8 weeks and sometimes even several months to make any impact on outcomes, so thought it might not be a bad idea to start it early.
@keikilove Thank you for this also. I don't think he checked my testosterone level with my most recent labs, so will ask about it the next time I call the clinic.
Admittedly, although I discussed this with my RE last cycle, I haven't been great about actually remembering to take them, which I blame on my wacky work schedules. I finally got a little pillbox for my purse (old lady status!) so that I could do a better job this month. So I'm thinking about them a little bit more now.
@photographerwife I'm not much help on the insurance side of things but krash had some good advice there. Glad you were able to take some time to destress this week; self-care is such an essential part of our overall well-being and it's one that's so overlooked. I feel like there's an expectation that since we're WFH that we shouldn't have that much to stress about if we're just sitting around in our PJs all day but I don't know about you, I'm more stressed than ever. I did laugh at your comment "I love all the food" - me too girl, me too. @lisa3379 glad you're feeling ok post-ER. The waiting is one of the hardest parts, but it sounds like you got a great first update so I’ll be keeping my fingers crossed for you for Tuesday’s report!!!
@keikilove there you are!! I’m sorry your IVIG treatments make you so sick. Let’s hope it is all worth it and you get that THB so soon!!
AFM, my champion of an RE came through for me again and without even having to harass him he decided he's going to see me again on Monday (tomorrow) for another US which makes me feel sooo much more at ease that we won't have any surprises on the 14th. By this time next week we’ll be PUPO!!
TTC History:
Me: 36 MH: 39, TTC since Dec 2017
Aug '18: PCOS dx
Nov '18: MH SA - 19mil
Dec '18-Mar '19: Letrozole + TI - all BFN
Apr '19: Letrozole + TI, - BFN. Repeat SA (27mil) & DNA fragmentation test (17%)
@quiltandknit Oh yes, the old lady pill box is a must once taking all these supps!😉 The frugal lil old lady in me found a hack: I put my daily pills for the day into a mini Altoids tin. This way I have it in my purse always and forget to take them less often.
Me: 41; MH: 40 | Met 02/2009 | Started Dating 08/2017 | Married 02/02/2020 Mar 2024 | consult to get established with a new reproductive immunologist (Alan Beer Center) Apr/May 2024 | required testing & waiting for a protocol May 2024 | protocol given / decided to go back to my old reproductive immunologist, Dr. Jubiz Jun / Jul 2024 | more testing, incl. SIS, ultrasound, and endometrial biopsy Jul 2024 | Dx chronic endometritis; 14 days of 100mg of doxy given Sep 2024 | Repeat endometrial biopsy; still + for chronic endometritis. 2 more antibiotics + an antiviral Oct 2024 | Hysteroscopy turned polypectomy; endometriosis consult w/ specialist who confirmed high likelihood of endo based on symptoms and ultrasound; lots of blood tests ordered Mar 2025 | Endo excision surgery. Stage 3 endo found! Recoveing Apr 2025 | Planning transfer w/ RE & green light protocol w/ RI; target transfer July or August 2025 May 2025 | Surprise BFP! EDD 1/11/2026
TTC #1
Me: 36, MH: 34 | Met 02/2009 | Started Dating 08/2017 | Married 02/02/2020 TTC #1 02/2020 - 07/2022 2009 | Dx PCOS; likely a misdiagnosis 07/14/20 | Dx Hashimoto's Thyroditis 07/21/20 | 1st RE appointment 07/2120 - 08/20/20 | so much testing; no signs of PCOS 08/20/20 | Dx Unexplained; AMA 09/08/20 | IUI #1 Clomid + Trigger + Prometrium | BFN 09/30/20 | Urology consult; more testing required 10/2020 | Clomid + OPK + TI + Prometrium | BFN 10/26/2020 | Starting 2nd IUI cycle, with Letrazole and with a new RE / different clinic 11/03/2020 | New Dx "poor egg quality"; IUI cancelled in favor of Trigger + TI + Prometrium | BFN 11/26/2020 | Combo IUI (Clomid + Menopur) + Trigger + Prometrium | BFN 12/20/2020 | Combo IUI (Clomid + Gonal-F) + Trigger | IUI Cancelled due to thin lining; TI only | BFN 01/14/2021 | Combo IUI (Letrazole + Menopur) + Trigger | BFN 02/06/2021 | Switched to a new RE (TEW) ; trying naturally until we complete additional testing 03/14/2021 | Hybrid Double IUI, with Zymot (Letrazole, Gonal-F) + Trigger + Endometrin | Ovulated 4 mature eggs but still a BFN ☹️ 04/07/2021 | Natural cycle while we regroup | BFN 04/09/2021 | Employer announces fertility benefits starting 05/01/2021! | Search for a new doctor who accepts insurance 05/10/2021 | New RE consult & plan for IVF 05/13/2021 | Mid-luteal IVF cycle #1 interrupted; had to get cancer genetic screening done to make sure I didn't have the same SDHA gene mutation as MH. 06/10/2021 | Aygestin priming IVF cycle #1; opted to Cx after 9 days of stims since only 5-6/12 follicles responded 07/26/2021 | Attempt #2 at IVF cycle #1 (mid-luteal start): 8 retrieved, 8 MII, 6 fert (1 PN3), 3 Day 5 & 6 blasts: 3AA, 3AA, 6AB; 3 euploid 08/09/2021 | Rest cycle / unmedicated TTC | Shockingly, a BFP! EDD: 5/25/202 | CP at 4w4d 09/23/2021 | IVF cycle #2 (mid-luteal start): 14 retrieved, 13 MII, 11 fert, 5 Day 5 & 6 blasts: 2 x 3AA, 2 x 3AB, 3BB; 2 euploid 11/12/2021 | IVF cycle #3 (mid-luteal start): cancelled due to ovaries being on vacation 12/20/2021 | Rest cycle / unmedicated TTC + Pregmune Immunology Testing; BFN 01/22/2022 | Rest cycle / unmedicated TTC + understanding uncovered immunological issues; BFN 02/18/2022 | Mock transfer cycle! ERA, ReceptivaDx, EMMA/ALICE; start Prednisone to address NK activity 03/16/2022 | Final, "Hail Mary" super-ovulation + TI cycle before FET; BFP! EDD: 12/21/2022 | MMC 05/08/2022 05/20/2022 | D&C; recovering... 06/21/2022 | Trying naturally until October 2022 07/21/2022 | BFP! EDD 04/02/2023; 👦🏼 born on 4/5/2023
Re: IF testing/treatment w/o 2/1
@keikilove Thank you for this also. I don't think he checked my testosterone level with my most recent labs, so will ask about it the next time I call the clinic.
Admittedly, although I discussed this with my RE last cycle, I haven't been great about actually remembering to take them, which I blame on my wacky work schedules. I finally got a little pillbox for my purse (old lady status!) so that I could do a better job this month. So I'm thinking about them a little bit more now.
@lisa3379 glad you're feeling ok post-ER. The waiting is one of the hardest parts, but it sounds like you got a great first update so I’ll be keeping my fingers crossed for you for Tuesday’s report!!!
AFM, my champion of an RE came through for me again and without even having to harass him he decided he's going to see me again on Monday (tomorrow) for another US which makes me feel sooo much more at ease that we won't have any surprises on the 14th. By this time next week we’ll be PUPO!!
TTC History:
Me: 36 MH: 39, TTC since Dec 2017
Aug '18: PCOS dx
Nov '18: MH SA - 19mil
Dec '18-Mar '19: Letrozole + TI - all BFN
Apr '19: Letrozole + TI, - BFN. Repeat SA (27mil) & DNA fragmentation test (17%)
Aug '19: Letrozole + HCG trigger + IUI + prog supp - BFN (MH: 16mil)
Sep '19: 2nd IUI, same protocol - BFN (MH: 16mil)
Dec '19: IVF #1 w/ICSI, PGT. 5 retrieved, 4 fertilized, 3 blasts, 3 PGT-A normal.
Mar '20: FET #1, perfect 5AA blast transferred. BFN.
Sept '20: FET #2, 5BB tsf. 9/18/20 BFP!! EDD: 5/27/21. MMC 11w
Feb ‘21: FET #3, last 6BB blast transferred. BFP, EDD 11/2/21. MC 5w3d.
May '21: IVF #2 w/ICSI, PGT. 8R, 7M, 6F, 6 blasts - 3AB, 3AB, 3BB, 4BB, 5BB, 6BA. Fresh tsf 5/13/21 - BFN.
June '21: PGT-A results = 3 abnormal, 1 low level mosaic. Referred to new REI, had consult with 2nd RE in between.
Sept '21: RPL, immune testing normal
Oct '21: IVF #3 w/IMSI, PGT. 33R, 26M, 23F, 9 blasts (7 day 6, 2 day 7). PGT-A = 5 normal, 1 mosaic
Dec '21: Positive for endometritis, RX Flagyl & Keflex
Jan '22: FET #5 - Kitchen sink immune/RIF protocol incl. PRP, intralipids, prednisone, medrol, nivestym, fragmin - CP
Feb '22: FET #6 - Kitchen sink immune/RIF protocol w/higher doses of pred & fragmin - BFN
Mar '22: Mock cycle for ERA - cancelled, repeat endometrial biopsy instead. Still positive for endometritis. RX ciprofloxacin & amoxicillin.
Apr '22: IVF #4 w/IMSI, PGT. 28R, 23M, 16F, 11 blasts. PGT-A = 6 normal.
June '22: FET #7 - Microdose lupron downreg w/kitchen sink immune/RIF protocol - double embryo transfer. BFN.
July '22: FET #8 - Mini stim w/Puregon + trigger, kitchen sink immune/RIF protocol. BFN.
Sep '22: Taking a break
Dec '22: Attempted abdominal myomectomy, fibroid too close to cervix and major blood vessels. Wasn't removed.
Feb '23: FET #9 - Modified natural w/baby asp, HCG trigger, PIO, PRP, Medrol, HCG wash, embryo glue - BFP!! EDD 11/11/23
@quiltandknit gurrrll, old lady status here all the way, à la @keikilove!!!
TTC History
TTC#2
Mar 2024 | consult to get established with a new reproductive immunologist (Alan Beer Center)
Apr/May 2024 | required testing & waiting for a protocol
May 2024 | protocol given / decided to go back to my old reproductive immunologist, Dr. Jubiz
Jun / Jul 2024 | more testing, incl. SIS, ultrasound, and endometrial biopsy
Jul 2024 | Dx chronic endometritis; 14 days of 100mg of doxy given
Sep 2024 | Repeat endometrial biopsy; still + for chronic endometritis. 2 more antibiotics + an antiviral
Oct 2024 | Hysteroscopy turned polypectomy; endometriosis consult w/ specialist who confirmed high likelihood of endo based on symptoms and ultrasound; lots of blood tests ordered
Mar 2025 | Endo excision surgery. Stage 3 endo found! Recoveing
Apr 2025 | Planning transfer w/ RE & green light protocol w/ RI; target transfer July or August 2025
May 2025 | Surprise BFP! EDD 1/11/2026
TTC #1
TTC #1 02/2020 - 07/2022
2009 | Dx PCOS; likely a misdiagnosis
07/14/20 | Dx Hashimoto's Thyroditis
07/21/20 | 1st RE appointment
07/2120 - 08/20/20 | so much testing; no signs of PCOS
08/20/20 | Dx Unexplained; AMA
09/08/20 | IUI #1 Clomid + Trigger + Prometrium | BFN
09/30/20 | Urology consult; more testing required
10/2020 | Clomid + OPK + TI + Prometrium | BFN
10/26/2020 | Starting 2nd IUI cycle, with Letrazole and with a new RE / different clinic
11/03/2020 | New Dx "poor egg quality"; IUI cancelled in favor of Trigger + TI + Prometrium | BFN
11/26/2020 | Combo IUI (Clomid + Menopur) + Trigger + Prometrium | BFN
12/20/2020 | Combo IUI (Clomid + Gonal-F) + Trigger | IUI Cancelled due to thin lining; TI only | BFN
01/14/2021 | Combo IUI (Letrazole + Menopur) + Trigger | BFN
02/06/2021 | Switched to a new RE (TEW) ; trying naturally until we complete additional testing
03/14/2021 | Hybrid Double IUI, with Zymot (Letrazole, Gonal-F) + Trigger + Endometrin | Ovulated 4 mature eggs but still a BFN ☹️
04/07/2021 | Natural cycle while we regroup | BFN
04/09/2021 | Employer announces fertility benefits starting 05/01/2021! | Search for a new doctor who accepts insurance
05/10/2021 | New RE consult & plan for IVF
05/13/2021 | Mid-luteal IVF cycle #1 interrupted; had to get cancer genetic screening done to make sure I didn't have the same SDHA gene mutation as MH.
06/10/2021 | Aygestin priming IVF cycle #1; opted to Cx after 9 days of stims since only 5-6/12 follicles responded
07/26/2021 | Attempt #2 at IVF cycle #1 (mid-luteal start): 8 retrieved, 8 MII, 6 fert (1 PN3), 3 Day 5 & 6 blasts: 3AA, 3AA, 6AB; 3 euploid
08/09/2021 | Rest cycle / unmedicated TTC | Shockingly, a BFP! EDD: 5/25/202 | CP at 4w4d
09/23/2021 | IVF cycle #2 (mid-luteal start): 14 retrieved, 13 MII, 11 fert, 5 Day 5 & 6 blasts: 2 x 3AA, 2 x 3AB, 3BB; 2 euploid
11/12/2021 | IVF cycle #3 (mid-luteal start): cancelled due to ovaries being on vacation
12/20/2021 | Rest cycle / unmedicated TTC + Pregmune Immunology Testing; BFN
01/22/2022 | Rest cycle / unmedicated TTC + understanding uncovered immunological issues; BFN
02/18/2022 | Mock transfer cycle! ERA, ReceptivaDx, EMMA/ALICE; start Prednisone to address NK activity
03/16/2022 | Final, "Hail Mary" super-ovulation + TI cycle before FET; BFP! EDD: 12/21/2022 | MMC 05/08/2022
05/20/2022 | D&C; recovering...
06/21/2022 | Trying naturally until October 2022
07/21/2022 | BFP! EDD 04/02/2023; 👦🏼 born on 4/5/2023