Trying to Get Pregnant

IF Testing and Treatment- Week of 10/16

24

Re: IF Testing and Treatment- Week of 10/16

  • @shortstack930 I know you touched on this in a previous post, but they want you to HIO before YH gives a sample for the IUI? Wouldn’t that hurt the numbers? (I thought it was 2-3 day abstinence) Maybe that’s just if MFI is an issue? Anyway yay! Hopefully I won’t be too far behind you :smile:
    Me: 38 DH:39
    TTC #2 - August 2016
    MFI
    IUI #1-3 BFN 

    Heart Mom - DS 3/15/13
    BFP 4/21/18 MMC 6/11/18
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  • @RVAmom315 they've always had us HIO either the day before or two days before IUI so that the sperm is better quality. The RE had said even if there were fewer sperm they would be good quality and would be put right up there during the IUI so abstaining wouldn't make a difference. I would imagine it would be different if MFI were an issue though. 
    TTC History
    Me: 35 DH: 34
    Married 07/2012
    DD born 07/2014
    DD2 born 10/2018
    DS born 10/2022

    IF history:
    TTC #2 since January 2016
    June-Aug 2017: 3 IUIs w/Clomid = BFN
    Sept 2017: Dx w/Endometriosis
    Oct 2017: IUI w/Letrozole = BFN
    Nov 2017: IUI w/Letrozole = BFN
    Dec 2017: pre-IVF testing
    Jan-Feb 2018: IVF--17 eggs retrieved, 13 fertilized, 9 frozen and 1 transferred on 2/10 = BFP on 2/19!!! EDD 10/29/2018
    FET Oct 2021: BFP on 10/31! MC at 5 weeks
    FET Feb 2022: BFP on 2/15! EDD 10/29/22


  • @zwink1 wow!!!  Crazy how your body must be ready to get this going!!! 
    Formally Leekat
    Me: 36 DH 38
    Married Sept 2014
    TTC Since Nov 2015
    IVF Cycle 1 - 0 eggs
    IVF Cycle 2 - 3 embryos
    FET 1 (transferred 1 embryo) - BFN
    FET 2 (transferred 2 embryos- BFN
    IVF Cycle 3 - 1 embryo
    FET 3 (transferred 1 embryo) - BFN
    Donor Egg Retrieval 2/19/18 -4 embryos that didn't make it to freeze
    Donor Egg Retrieval 4/30/2018 - 6 eggs - 5 embryos frozen Day 3
    FET 4 (with donor eggs) (transferred 1 embryo) -BETA 7/10 - BFN
    Hysteroscopy & Endo Scratch 
    FET 5 (with donor eggs) (transferred 2 embryos)-BETA 9/10 - BFN
    Final FET (#6) (with donor eggs) (transferred 2 embryos) BETA 10/15 BFP!!
    EDD: June 24, 2019 Baby O born June 26, 2019

  • @zwink1 That's amazing! You're on your way! GL!


  • @zwink1 You're on your way now!
  • @zwink1 yes! Time to get the ball rolling!
  • RVAmom315RVAmom315 member
    edited October 2017
    @zwink1 Your body knows its time! Good luck!
    Me: 38 DH:39
    TTC #2 - August 2016
    MFI
    IUI #1-3 BFN 

    Heart Mom - DS 3/15/13
    BFP 4/21/18 MMC 6/11/18
  • @shortstack930 Good luck today!!!

    @RVAmom315 And good luck to you too today!!  Hope your scan goes well!  Also I was thinking the same thing for @shortstack930 and getting it done last night.  I was sitting here thinking noooooooooo!  But yea....#MFIIssues

    @zwink1 nice!! You're body is like ok, let's get this show on the road!
  • @shortstack930 GL today!!!
    Me: 38 DH:39
    TTC #2 - August 2016
    MFI
    IUI #1-3 BFN 

    Heart Mom - DS 3/15/13
    BFP 4/21/18 MMC 6/11/18
  • @zwink1 yay! That is so exciting!!
  • @zwink1 - I know AF is always hated, but I feel like this was a nice little surprise! Yay, I love that the ball is rolling. You are THIS much closer to your baby!!!!


    TTC #1 since September 2014
    Diagnoses: RPL, Endometriosis, MFI (count, morph, DNI, DNAS, multiple bilateral subclinical varicoceles), low progesterone
    Check out my Infertility blog 
    Check out my Infertility Instagram

    Loss History (TW):
    BFP: 3 May 2015, loss confirmed 4 June 2015
    BFP: 15 August 2015, loss confirmed 23 August 2015
    BFP: 16 November 2015, loss confirmed 22 November 2015
    BFP: 18 July 2016, loss confirmed same day
    BFP: 04 March 2018, loss confirmed 23 March 2018
    BFP: 12 June 2018, TWINS; D&C 06 July 2018
    TTC History (TW):
    3 losses in 2015
    Met with OBGYN in January 2016
    Me: all clear, H: OAT
    November 2016: HSG = All Clear!
    January 2017: H tested again,  High DNA fragmentation and stainability
    February 2017: Clomid + TI + Progesterone = BFN
    March 2017: Clomid + HCG + IUI + Progesterone = SA/wash: zero count on attempt #1, <1,000 on attempt #2= BFN
    Varicocele Embolization- 5 May 17
    December 2017 SA: Zero improvement after embolization
    January IVF- 25 retrieved, 11 mature, 8 fertilized, 3 frozen day fives (3AA, 3AA, 3AA), 1 frozen day 6 (5BB), 1 frozen day 7 (3CC)
    Three PGS normal (3AA, 3AA, 5BB), one inconclusive (3AA)
    FET #1: 27 February 2018, 3AA & 5BB, one stuck! BFP 04 March 2018.... Loss confirmed 23 March 2018
    May 2018: SHG/SIS = all clear "beautiful uterus"
    FET #2: 04 June 2018, 3AA PGS normal embryo, 3AA PGS hatching inconclusive embryo. 
    BFP: 12 June 2018, EDD 20 February 2019
    Ultrasound, 25 June 2018: There are two
    Lost Baby A 02 July 2018
    Baby B not growing, D&C 06 July 2018
    Laparoscopy, hysteroscopy, chromotubation: 23 July 2018: blocked right tube, heavily inflamed, covered in endo. Removed right tube. Removed more endo from uterus, tubes, ovaries. Endo remains on bladder and bowel. 
    Next Up:
    TTC Naturally, possibly IUIs for remainder of 2018. 
    ER#2 ~Jan 2019
            

  • @zwink1 yay for a good consult and moving forward!!!!

    @kiwi2628 sounds like a great plan!!! I wanted to ask my doc about doing half natural and half ICSI because I really wanted to also see if they would fertilize. Did he say why he was interested in doing it that way? 

    @RVAmom315 good luck!!! 
  • @beachbunnyxo123 I should say that my RE did say it was all mature egg number dependent- like if I only have 8, he would recommend ICSI for all just in case. If I have 20, then he may do half and half. He also says for most people with unexplained they start with natural, but I made it clear I wanted to be....aggressive, so he said we could do ICSI to up our chances.
  • @darkstar42 - what was YH's SA like? Did he test normal too? You may have already mentioned his results on another post - sorry if I missed it!

    I guess the protocol makes sense since this is your first rodeo. You probably shouldn't jump into injects until you see how you respond to gentler stimulation. Sorry your RE didn't give you more personalized care, though :\ I think these doctors get into a pattern and think "This worked for the majority of my patients in your situation so it will work for you, too." Given your insurance covers IUI starting with that to see how it goes seems like a prudent choice.

    Are there other REs nearby you can see, or anyone else in the same practice who has a better bedside manner? That can make a difference in how satisfied you are with your treatments, for sure.
  • @darkstar42 per your concerns about your RE: its super important to like and trust your RE, so if you don't feel that, absolutely look into finding another. With that said, a lot of IF is kind of cookie cutter. With few exceptions: try medicated IUI hoping it works, then move onto IVF if it doesn't. Thats especially true for unexplained, since there is nothing concrete to treat/chase after, they try medicated IUI first and then after 3-4 cycles move on to IVF, so I wouldn't worry about treatment being too personalized on the first cycle. They can also tailor it more based on your response to the first cycle if they feel the need.
  • @zwink1 Yay for getting moving!! Sounds like your body was ready to get this show on the road :)

    GL today @shortstack930!!

    @darkstar42 YGPM

    Me: 32 DH:33
    Married 9/2015
    TTC #1 6/2016
    BFP: 4/21/2017 - CP
    Dx Unexplained IF 6/2017
    Clomid + Ovidrel + IUI 7/2017 - Cancelled (overstimulated)
    Letrozole + Ovidrel + IUI #1 - BFN
    Letrozole + Ovidrel + IUI #2 -BFN
    Letrozole + Ovidrel + IUI#3 - BFP! EDD July 15 2018
    Baby Girl H - July 22 2018


  • @wishiwaspreggo MH's SA was good, except that morphology was a little bit low (3%, when the cutoff for "normal" is 4%). The RE didn't seem at all concerned about that and didn't want to do any further tests on MH. My AMH is relatively high (5.72), so the RE thinks I would respond well to a low dose of letrozole (5mg). We were actually hoping for a less aggressive approach to begin with, rather than more aggressive. Mostly because I still haven't come to terms with an IF diagnosis.
    @kiwi2628 That is very helpful to hear. I think this is all so new to me that I keep thinking, yeah, but there must be SOME explanation! Basically I'm having a case of "I'm a special snowflake!" I'm also nervous about the medications because I tend to be someone who gets the weird drug side effects. When they say "only 7% of people will experience xyz side effect," I'm usually in that 7%. Taking hormones scares me because, although I logically know this is a totally different drug, birth control pills were a nightmare for me. Major mood effects on three different very low dose pills. I think switching to a doctor who will acknowledge my concerns would make me feel a lot better about everything.
  • Redpuma119  I got the Reli-On BBT from Walmart (like, the generic Mabis). I've read that it's the same, but with a different name?  No idea. I price checked getting another Reli-On from Walmart vs. a Mabis from Amazon... and decided I'd go with Amazon.  Sanity is definitely worth $8!

    MC #1: D&C Oct 23, 2015 (7.5 weeks)
    MC #2: July 1, 2016 (5.5 weeks)
    MC #3: October 17, 2016 (CP)
    RE #1: RPL testing November 2016-January 2017
    MC #4: Feb. 28, 2017 (CP)
    RE #2: Additional RPL testing March-November 2017
    MC #5: January 2019 (6.5 weeks)

    RE #3: More testing 2023. 
    Egg Retrieval Sept/Oct 2023, 2 good embryos after PGT-A testing.
    Surgery for endometriosis January 2024
    Lupron Depo March 2024.  Benched 3 months.

    FET #1: June 3, 2024 (failed)

    Lupron Depo June 2024. Benched 3 months again before next FET.

    FET #2: September 2024 (failed)

    FET #3: December 2024 (failed)

    #BitterHagPartyOf1

  • @Redpuma119 this is my second cycle on letrozole. I have had like no side effects from it. None. I didn't produce as many eggs on letrozole as I did on clomid though (2 as opposed to 3 or 4)
  • I can love tit! Thanks @kiwi2628. The nurse I spoke to didn't say anything about checking.. maybe I should ask!
  • @kiwi2628 yes that completely makes sense depending on how many mature eggs are retrieved I totally agree with that!

    @Redpuma119 I’ve been on letrozole for about 7 different cycles. Barely any side effects at all I was just teary and emotional at times but any hormone med will do that. My REs never put me on clomid. Only thing is I produced about 1-2 mature follies from it each cycle which could’ve been the same for me with clomid though so who knows 
  • @RedPuma119 This is my third cycle with Letrozole. I have had very minimal side effects with it, just some bloating and moodiness, and I usually produce 1 mature follicle. However, my first very cycle was a clomid cycle where I ended up overstimulating, and for that reason I now only take a 2.5mg dose of letrozole.
    Me: 32 DH:33
    Married 9/2015
    TTC #1 6/2016
    BFP: 4/21/2017 - CP
    Dx Unexplained IF 6/2017
    Clomid + Ovidrel + IUI 7/2017 - Cancelled (overstimulated)
    Letrozole + Ovidrel + IUI #1 - BFN
    Letrozole + Ovidrel + IUI #2 -BFN
    Letrozole + Ovidrel + IUI#3 - BFP! EDD July 15 2018
    Baby Girl H - July 22 2018


  • @darkstar42 - Letrozole has minimal side effects so I wouldn't worry about it too much. Clomid seems to be the culprit for a lot of people when it comes to impacting mood, hot flashes, etc. You'll be on such a low dose I doubt you will notice anything.
  • I just got a very disappointing/concerning call from the RE’s office. Originally they said we wouldn’t get our day 5 report until Friday and I almost wish they would have just waited until then. 

    They said only 2 made it to day 5 and they are watching 2 more. They also said they will not be able to do PGS testing on any of them, given the number of cells that they are seeing. To add insult to injury, they still said we won’t be able to do our FET until December. 

    I feel like I’ve somehow done something horribly wrong. How did we go from 16-18 fertilized to only 2 making it? Even if the other 2 do make it, that’s a horrible percentage. And I am really torn up about not being able to do the PGS testing. I just want to leave work and cry. 
    Me: 35 DH: 28
    TTC since June 2016

    Azoospermia diagnosis (zero count) Dec 2016

    AZFc chromosome microdeletion discovery March 2017
    Unsuccessful TESE for DH in August 2017
    October 2017 IVF with donor sperm
    29R, 24M, 16F, 2d5, 4d6 (6 embryos total)
    Only 3 could have PGS. 2/3 normal. 5 embies frozen
    12/15/17 FET #1 (1 embryo)--CP
    2/7/17 FET #2 (2 embryos)--BFN
    Chronic endometritis diagnosis May 2018
    ERA Sept 2018--borderline receptive--12 more hours of progesterone
    Abnormal SIS Oct 2018
    Repeat hysteroscopy Nov 1. Treated recurring endometritis.
    12/4/18 FET #3 (2 embryos)--BFN
    Our journey has come to an end.
    ~*~*~Nevertheless, she persisted~*~*~
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