Hi all,
I have DOR. My first IVF cycle we used BCP for three weeks and then microdose flare protocol (Lupron 20 and Follistim 300 am and pm). I produced five eggs, 4F, three 3dt, one frozen on 6th day, none stuck. For my next cycle my RE does not want to use BCP because she thinks that it suppressed me too much. But we are still doing microdose lupron flare. I have heard from a few people that these natural cycles without BCP (or even estrace) are the worst. Eggs can be all over the place with their sizes and some people produced even less. Has anyone had a similar experience? Can you please share your experiences? Should I force my RE to change my protocol? If you used both BCP and estrace, which one worked better for you if you are DOR?
---- Siggy warning ------
Me 34 y/o DH 35 y/o
IVF#1 (ICSI)-- April 2014-- MDL with BCP, 5R, 4 ICSID, 3dt with three embryos, 1 six-day freeze (2BA grade)-- BFN
IVF#2.1 (ICSI)-- August 2014: MDL without BCP-- cancelled
Natural IUI on 11/8 -- BFN
IVF#2.2 (ICSI)--Nov/Dec 2014: MDL without BCP, 5R, 1 ICSID, frozen on day 6 (grade 2BB)
FET #1: transferred two 5 (or 6?)day embryos on January 27. Beta #1 (2/4): 158, Beta #2 (2/6): 391 Beta #3(2/9): 1187 BFP!
First u/s at 5w1d showed one gestational sac and yolk sac. Second u/s at 6w showed heartbeat at 102. Third u/s at 7w heart rate 145. EDD 10/15/2015
Re: suppression or no suppression
::: Married June 2003:::
TTC #1 since: Aug. 2008
Me: 34, DOR, MTHFR-A1298C (heterozygous), decreased blood flow to uterus, Mild Endo
DH: 38, Balanced translocation 5&10, unexplained MFI, normal SA and SCSA
Tx History: IUI 1&2= BFN
IVF# 1 W/ICSI= BFN
IVF# 2: cancelled d/t no response
IVF# 3= 1 egg retrieved=immature/not viable
IVF# 4= c/p
***CCRM ODWU***
Found DHs BT and Me-decreased blood flow to uterus
Recommended DE IVF w/PGD, incorporate electro-acupuncture. Decided to cycle locally
***New RE***
DE IVF# 1(cycle #6) w/pgd, (freeze all): 30R, 23M, 15F, slow/poor embryo development, 4 biopsied, 1 Normal "Norm"; DE IVF w/PGD, incorporate electro-acupuncture.
IVF# 6: (OE/DS) cancelled
IVF# 7: (OE/DS) 1R, 1M, 1F, arrested day 5
Plan-DE IVF# 2 (cycle #8): DE/DS in May 2015
http://icanhazbabyz.blogspot.com/
10/11: after 2 years, saw a RE, FSH 5.4
11/11: BFP! (surprise after thyroid & normal hsg),
12/11: missed m/c after 7 week u/s, 1/12: D&C
6/12 IUI#1-IUI #3: clomid = BFP!, C/P
IVF #1(10/12) FSH 5.4, AFC: 16 long Lupron, 5R/5M/4F, all 4 made it to 5dt, 1 blast/1-8 cell transferred=BFN
IVF #2(12/12)AFC 21, MD lupron, 4R/4M/3F, 5dt of 1 blast and 2-8cell. BFN.
IVF#3(4/13) Natural start antagon protocol, 12R,11F. one PGS normal at day 6 transfer. BFN.
IVF#4 (11/13) C.CRM (ODW.U normal 8/13 Still no Diagnosis) EPP/antagonist. ER 13R/7M/6F. Only 1 made it to freeze. Abnormal. Looking into options of DE, Fresh vs frozen.
10/14 new local RE to look into what's next. CD3 FSH 4.7, AMH 0.9. Met with DE agencies and exploring options for feb/march 2015.
Surprise natural bfp (4 days before donor is signed). Beta #1 at 9dpo: 51.8, 2nd beta: 195 (25 hours doubling) @11dpo. 3rd beta (12/15): 516 (35 hrs doubling) 4th beta(12/17): 895 (58 hours doubling) 5th beta(12/19): 2120. U/S at 5w0d(12/22): one gestational sac with yolk sac. U/S #2 (6w0d)12/29. One little bean measuring 6w0d with HR 124. 3rd u/s(1/4)7w0d: baby measuring 7w2d. HR 134. 3/30: A/S at MFM went great except for low lying placenta. Verifi results are normal! Team Blue! Please send any positive thoughts our way! EDD:8/24/2015
Baby Will born 8/18. He's perfect.
---- Siggy warning ------
Me 34 y/o DH 35 y/o
IVF#1 (ICSI)-- April 2014-- MDL with BCP, 5R, 4 ICSID, 3dt with three embryos, 1 six-day freeze (2BA grade)-- BFN
IVF#2.1 (ICSI)-- August 2014: MDL without BCP-- cancelled
Natural IUI on 11/8 -- BFN
IVF#2.2 (ICSI)--Nov/Dec 2014: MDL without BCP, 5R, 1 ICSID, frozen on day 6 (grade 2BB)
FET #1: transferred two 5 (or 6?)day embryos on January 27. Beta #1 (2/4): 158, Beta #2 (2/6): 391 Beta #3(2/9): 1187 BFP!
First u/s at 5w1d showed one gestational sac and yolk sac. Second u/s at 6w showed heartbeat at 102. Third u/s at 7w heart rate 145. EDD 10/15/2015
::: Married June 2003:::
TTC #1 since: Aug. 2008
Me: 34, DOR, MTHFR-A1298C (heterozygous), decreased blood flow to uterus, Mild Endo
DH: 38, Balanced translocation 5&10, unexplained MFI, normal SA and SCSA
Tx History: IUI 1&2= BFN
IVF# 1 W/ICSI= BFN
IVF# 2: cancelled d/t no response
IVF# 3= 1 egg retrieved=immature/not viable
IVF# 4= c/p
***CCRM ODWU***
Found DHs BT and Me-decreased blood flow to uterus
Recommended DE IVF w/PGD, incorporate electro-acupuncture. Decided to cycle locally
***New RE***
DE IVF# 1(cycle #6) w/pgd, (freeze all): 30R, 23M, 15F, slow/poor embryo development, 4 biopsied, 1 Normal "Norm"; DE IVF w/PGD, incorporate electro-acupuncture.
IVF# 6: (OE/DS) cancelled
IVF# 7: (OE/DS) 1R, 1M, 1F, arrested day 5
Plan-DE IVF# 2 (cycle #8): DE/DS in May 2015
http://icanhazbabyz.blogspot.com/