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Third IVF attempt not responding to estradiol and patch!

this is my third IVF attempt have been on estradiol and also vivelle dot patch. Did fine during the second attempt. This is for a frozen cycle. Has anyone ever encountered this too? Or know anyone that didn't get a great response with these meds? I started bleeding a few days before my scheduled first bloodwork and ultrasound before the transfer. Nurse told me I could've ovulated but didn't give me much feedback. I'm not handling this very well :(
*Married 2 years* TTC for 1year and a half I have had 2 D & Cs to treat uterine polyps..otherwise no issues.. Hubby showed zero sperm count.. Had surgery to correct vas deferens..low sperm count presently. Starting my first IVF cycle November 2012 pending getting my period ASAP! Otherwise January is when we will try IVF again. IVF postponed until February, due to change in health insurance! Started lupron 2/17/13 hoping for a positive result in April!

Re: Third IVF attempt not responding to estradiol and patch!

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    You may need to add Lupron into the mix for your next FET cycle...I needed Lupron to prevent my numbers from being all over the place. I hope your next cycle goes better!
    | Married since 2008 | DH and I: Both 30 | Me: Endometriosis and Carrier of an X-Linked Dominant Genetic Disorder | DH: Low Morph | Planning IVF with PGD and PGS in 2013 | Freeze-All IVF #1: March 2013 ER 3/26. 29R, 12M, 11F. 4 5AA frozen blasts. Freeze-All IVF#2: May 2013 ER 5/15. 31R, 21M, 20F. 6 5AA frozen blasts. Our PGD probe was completed in late June (total of 20 weeks to develop). PGD and PGS Results came on 6/19: 3 healthy embryos (normal chromosomes and unaffected by my family's genetic disorder). FET #1: July 2013 Natural Cycle - Cancelled due to insufficient lining (only got to 7.5mm). FET #1.2: August 2013 - Medicated Cycle with Lupron & Estrogen Patches to build up lining. Single embryo transfer was 8/23. Beta #1: 240! Beta #2: 578! U/S on 9/19 at 6w4d: We saw the heart beating at 131bpm. Second U/S on 10/4 at 8w5d: We saw the heart beating at 178bpm. EDD 5/11/2014
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    PAIF/SAIF/Everyone Welcome! 


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    Thanks for the response. Just so disappointed since I responded well during the first FET.
    *Married 2 years* TTC for 1year and a half I have had 2 D & Cs to treat uterine polyps..otherwise no issues.. Hubby showed zero sperm count.. Had surgery to correct vas deferens..low sperm count presently. Starting my first IVF cycle November 2012 pending getting my period ASAP! Otherwise January is when we will try IVF again. IVF postponed until February, due to change in health insurance! Started lupron 2/17/13 hoping for a positive result in April!
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    I'm so sorry. I had to do one cancelled FET cycle before figuring out what my body really needed. I really hope your RE has a good plan for you this next time if you get cancelled. Mine did, and I was able to get started right away!
    | Married since 2008 | DH and I: Both 30 | Me: Endometriosis and Carrier of an X-Linked Dominant Genetic Disorder | DH: Low Morph | Planning IVF with PGD and PGS in 2013 | Freeze-All IVF #1: March 2013 ER 3/26. 29R, 12M, 11F. 4 5AA frozen blasts. Freeze-All IVF#2: May 2013 ER 5/15. 31R, 21M, 20F. 6 5AA frozen blasts. Our PGD probe was completed in late June (total of 20 weeks to develop). PGD and PGS Results came on 6/19: 3 healthy embryos (normal chromosomes and unaffected by my family's genetic disorder). FET #1: July 2013 Natural Cycle - Cancelled due to insufficient lining (only got to 7.5mm). FET #1.2: August 2013 - Medicated Cycle with Lupron & Estrogen Patches to build up lining. Single embryo transfer was 8/23. Beta #1: 240! Beta #2: 578! U/S on 9/19 at 6w4d: We saw the heart beating at 131bpm. Second U/S on 10/4 at 8w5d: We saw the heart beating at 178bpm. EDD 5/11/2014
    image
    PAIF/SAIF/Everyone Welcome! 


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    This is what always happened to me. We tried pills, patches, vaginal Estrace, Viagra, neupogen and finally ended up doing stims. The only way we could get me to build a lining and not bleed was to stimulate my ovaries to make natural estrogen. I usually made it to about day 10 during a fet cycle when I would start to bleed. It's a uncommon reaction and some drs don't know alternatives to treat.
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    I'll know more tomorrow! Of course this would happen to me on my 30th bday to top it off! Thanks ladies! And good luck to you and your journey thru this xo
    *Married 2 years* TTC for 1year and a half I have had 2 D & Cs to treat uterine polyps..otherwise no issues.. Hubby showed zero sperm count.. Had surgery to correct vas deferens..low sperm count presently. Starting my first IVF cycle November 2012 pending getting my period ASAP! Otherwise January is when we will try IVF again. IVF postponed until February, due to change in health insurance! Started lupron 2/17/13 hoping for a positive result in April!
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