I'm supposed to start pio tomorrow. Initially the re said in the am, but said I could do pm if I need to be able to have someone else do them. I'm also doing crinone daily 12 hrs apart from the shot.
I've never done pio, so for those that have, I need an opinion. Is it better to do it in the am or pm? Thanks!!
"Everything will be alright in the end. So if it's not alright, it is not yet the end."
Me:29 DH:29 TTC since 1/11 Dx: unexplained IF/early DOR/immune issues
Feb'12- July'12-testing(all clear minus slight arcuate ute), 3 IUI with clomid all BFN
8/30IVF#1 Antagonist protocol- ER 9/11-8R, 7M, 5F.
ET 9/14 2 embies transferred. 1 10cell Grade 4, 1 8cell Grade 4. No frosties. BFN
IVF#2 Antagonist protocol plus baby aspirin- ER 12/5-16R, 12M, 8F!
ET 12/10 5dt! 1 fully expanded blast & 1 early blast. No frosties. BFN
3/13 hysteroscopy & polypectomy, Consulted w Dr. Kwak-Kim.
DX: High NK cells, cytokines, DHEAs& PAI1; hypothyroid, +APA, restricted bloodflow
7/13 IVF#3 Long lupron protocol with PIO, Crinone, Prometrium, and vivelle
(plus synthroid, metformin, baby asa, metanx, PNV, Vit E, D, calcium, fish oil, CoQ10, IVIg infusions and lovenox per Dr. Kwak-kim)
ER 7/19 14R, 11M, 9F(4 natural fert, 5 with ICSI)
ET 5dt 7/24 2 fully expanded blasts. SURPRISE 3 FROSTIES!!!
Beta #1 8/2 335!!!! Beta #2 829!!! 1st u/s 8/14 showed TWINS!!!!!
11/11: TEAM PURPLE!!!!!
3/21/14-L&W born at 37w via csection
Here Comes the Sun Blog
PAIF/SAIF welcome!
Re: pio poll
I've only done them in the evening. I do them around 7pm, massage, walk around some, and sit on a heating pad if need be.
Also, I have to say that the PIO is much better than the vag. pills. It really has only hurt a couple times if we got a bad spot, and i was only sore the first few days. Now it's nothing. You just have to get past that first week and then it's easy!
11/1- IUI#1,12/1- IUI#2, 1/2- IUI#3 all BFFN
IVF#1. Long Lupron.ER 3/8 10R,4M,5F. ET 3/3-one 1AB, 2 frosties 5dp5dt-BFP!! Beta 3/25-794 Beta 3/27- 1794
First u/s 4/8 saw hb. 4/22 missed mc 8w3d. d&c 4/26
FET #1- bcp start 6/9. ET 7/12. 2 perfect blasts.5dpt-BFP!!
m/c #2 missed m/c discovered 12/11/08 @ 8w3d :: d&c 12/15/08
Feb 2009-began seeing an RE:: DX with unexplained IF
Sept 2009 -2010 TTC using femara ...eventually work called me out of town.
June 2011 DX with thyroid cancer-forced to put baby making on hold
11/15/12 IUI #1 BFN and 12/15/12 IUI #2 BFN
Feb 2013 IVF-BFN:: April 2013 FET-Cancelled:: July 2013 FET-1 frostie
**Siggy/Ticker Warning**
TTC #1 since May 2012
May 2013: First R.E. appointment
DH: SA is good
May 2013: CD3 Blood work-normal
June 2013: Hsg-Right tube blocked
July 26, 2013: Starting Follistim for IVF #1
August 2013: IVF #1 Cancelled- Abnormal embryos
October/November 2013: IVF #2 w/ICSI
November 8, 2013: Transferred two early blasts (no frosties)
November 18, 2013: First EVER BFP!
Beta#1: 91 Beta#2: 288
1st U/S- 5w2d Saw yolk sac!
3rd U/S- 7w4d HB of 157bpm!
TEAM BLUE!
http://movingtolight.blogspot.com/
June- Femara 7.5mg + Trigger + IUI = BFN August- Lap & Hysteroscopy = Blocked & Partially Blocked Tubes
September- Femara 5mg = CX - No Response on Left = BFN October- 100mg Clomid + Trigger + TI = BFN
IVF # 1: Stims 11/30 ER 12/12/12! (10R, 10M, 8F, 2T, 6 F) :: Beta #1- 176 c/p @ 4w4d
FET #1 February 26th :: Lost 4 to Thaw, Transferred 2 = BFFN
IVF # 2 Stims 5/10 ER 5/21 (15R, 13M, 13F, 2T, 7F- 6d3 & 1d5) :: Beta # 1- 15 c/p @ 4w
FET #2.2 Scheduled for September 20th
2 Thawed, 2 Transferred! Beta #1- 96, Beta #2 906! :: EDD June 10th
2015- 2 failed FET. We are done
SURPRISE! BFP 8/8/16 EDD 4/1/17
**Sig warning***
TTC since 9/2011. DH - 32, me 32.
IUI#1 (natural): BFN; IUI#2 (clomid): BFN; IUI#3 (clomid and follistim): BFN.
IVF #1 March 2013, freeze all (OHSS).
FET#1 June: BFN
FET#2 August: delayed due to thin lining (6.3). Took a few months off to try and thicken the lining with lots of estrodial. FET#2.2 December: Cancelled due to thin lining (4.8). Two frosties left.
*New RE* Sonohystrogram and hystereoscopy done in Feb.
IVF #2: ER 3/4/14 ET 3/7/14, transferred 3, 3 day 9 cell perfect embryos. No frosties.
Beta #1 (14dp3dt) 504
Beta #2 (21dp3dt) 11,561
First ultrasound on 4/3/14 showed 3 sacs: one empty and two with beating hearts!! At 7w2d, found out that one baby did not have a heartbeat anymore. Praying that baby B makes it. Baby B is a girl!
EDD 11/25/14 BORN 11/29/14
**PAIF/anyone welcomed to comment!! Thank you.
I prefer p.m. That is what my RE recommended and that seems to work best with my schedule. I found that using heat after (microwavable compress or heating pad) and sort of massaging the area with it works well to prevent soreness and lumps the next day and there is more time for that in the evening.
***SIGNATURE WARNING***
TTC #1
Me 42, DH 47
Dx = AMA/DOR, MFI
IVF/ICSI #1 = BFN
IVF/ICSI #2 = BFP; early loss
IVF/ICSI #3 (DE) = BFP; early loss
FET = BFN
IVF/ICSI #4 (DE w/ CCS) = BFP
Beta #1 @ 10dp6dt = 265; Beta #2 @ 14dp6dt = 1251.
1st U/S @ 6w2d showed one perfect little heartbeat!
2nd U/S @ 7w2d. HB 132 & everything measuring on track.
Our beautiful little girl arrived January 2015!
TTC Since Aug 2011/
ME:34 all clear/DH:41 DX Severe MFI/
IVF w/ICSI OCT 2012 Stims started 10/8/ER 10/19/12/ET 10/24/Beta#1 11/2=BFN (beta was 1.2)
IVF 2.0-Baseline 11/7/12 beta 0/All Clear
Stim start 11/7/12//ER 11/19 11M//10F
ET 2 embies 11/24//Beta#1 28 Beta #2 23 Beta#3 29
stop meds Beta#4 37/C/P 5W5D EDD:8/12/13/IVF#3 in Jan
Ivf 3-frozen 3 poor 3day/fet=bfn
My Chart//>
Evening about an hour before bed. We are pretty quick at it now, DH assembles the shot while I feed the kitties, gives the shot, and then I change the kitty waterbowls, brush my teeth, shut the blinds, all the nightly chores.. I think the walking around the house after the shot helps.
I use Progesterone in Ethyl Oleate and I like it better than the sesame oil. The prog ethyl oleate is thinner, you can use the 25gauge needle, goes in pretty quick. The sesame we had to use a larger needle, and took longer to push in...
Best of luck
Me = 39 DH = 50 TTC (since 01/2009 after a short break, I stopped counting *cycles* in 2010)
DX 2010 : Unknown Infertility , AMA
HSG 2005 = Normal / HSG 2010 = Normal
SA 2005 = Normal / SA 2010 /2012 = Slightly low count : motility, morphology GREAT!
Chromosomal analysis, MTHFR, ANA's, Lupus, Protein C, Protein S, APCR = Normal 2011
M/C : 2005 (7wk), 2010 (6wk), 2011 (7wk)
8 IUI's 2010-2011 all BFN
IVF/ICSI antagonist 01/2012 #1 = BFN
IVF/ICSI antagonist long 06/2012 #2 = BFN
IVF/ICSI/CGH MDLF New Clinic/New RE 11/2012 #3 = One beautiful boy blasty frozen PGS normal
IVF/ICSI/CGH MDLF 02/2013 #4 = One more beautiful boy blasty frozen PGS normal
FET 6/20 : One 5AA PGS normal transferred Beta 1 6/28 = 53.9 / Beta 2 7/1 = 220 / Beta 3 7/3 = 550!
1 U/S 6w3d - Heartbeat 119 / 2 U/S - 7w5d- Heartbeat 169 / 3 U/S (OB) 8w5d - Heartbeat still great!
Baby G welcomed into the world 3/7/2014
SAIF / PAIF always welcome ****
June- Femara 7.5mg + Trigger + IUI = BFN August- Lap & Hysteroscopy = Blocked & Partially Blocked Tubes
September- Femara 5mg = CX - No Response on Left = BFN October- 100mg Clomid + Trigger + TI = BFN
IVF # 1: Stims 11/30 ER 12/12/12! (10R, 10M, 8F, 2T, 6 F) :: Beta #1- 176 c/p @ 4w4d
FET #1 February 26th :: Lost 4 to Thaw, Transferred 2 = BFFN
IVF # 2 Stims 5/10 ER 5/21 (15R, 13M, 13F, 2T, 7F- 6d3 & 1d5) :: Beta # 1- 15 c/p @ 4w
FET #2.2 Scheduled for September 20th
2 Thawed, 2 Transferred! Beta #1- 96, Beta #2 906! :: EDD June 10th
2015- 2 failed FET. We are done
SURPRISE! BFP 8/8/16 EDD 4/1/17
IF, 5 losses, 1 son, 1 on the way.
9 IUIs = 9 BFNs
IVF October 2012: 22 eggs retrieved, 17 fertilized, 5 frozen
ET #1: 1 blast = BFP; Blighted ovum discovered at 7w5d; D&E
FET #1: 1 blast = BFP; Missed m/c discovered at 9w5d; D&E
Karyotyping: normal ~ RPL Testing: normal ~ Hysteroscopy: normal
FET #2: 1 blast transferred 10/25; BFP 10/31!
EDD 7/13/14 ~ Induced at 37w4d due to pre-eclampsia ~ Born on 6/28/14
*Everyone welcome*
This is what we do, although I've only taken one so far.
Three ectopic preganacies in left tube in 1999, 2003 and 2004. HSG in 2010 concluded left tube blockage. IUI with femara in 2012 BFN. IVF #1 June 2013, 20 retreived, 14 mature, 12 fertilized via ICSI, one transferred, four frozen, BFN. FET in September 2013 - BFN:( FET #2 April 2014 - BFP!!!!
Whoever watches the wind will not plant; whoever looks at the clouds will not reap. As you do not know the path of the wind, or how the body is formed in a mother’s womb, so you cannot understand the work of God,the Maker of all things. <?xml:namespace prefix = o />
Ecclesiastes 11 4:5