TTC After a Loss
egsquared
member
Adding MTHFR to the diagnosis
egsquared
member
I don't know how these blood tests weren't done before by the first RE, but I just got an email from the current RE's nurse saying this last round of testing shows I'm compound heterozygous for MTHFR. Yay. Let's just add that to my LPD, low AMH and the fact that I'm AMA. I'm seriously starting to feel like everything is wrong with me. It's getting depressing. I'll start adding baby aspirin today and we'll do lovenox starting at transfer for the IVF cycle in January.
I've seen some posts recently about MTHFR on here, so I know I'm not alone I'm not alone in dealing with this. Anyone have a similar MTHFR diagnosis and protocal?
Also, whenever I see "MTHFR", in my mind I think "mother flucker." Anyone else? 
TTC #1 since 6/08. Cycle #6 - BFP 12/22/08, EDD 9/3/09, DD 8/14/09 at 37w1d
TTC #2 since 6/11
me=36 - low AMH, DH=38
BFP #2 - 8/31/11, EDD 5/10/12, M/C 9/23/11
BFP #3 - 3/4/12, EDD 11/14/12, CP 3/11/12
BFP #4 - 5/9/12, EDD 1/19/13, CP 5/11/12
BFP #5 - 8/22/12, EDD 5/5/13, CP 8/24/12
IVF#1 - January 2013 - EPP/Antagonist - 7R, 3M, 2F, 3dt of 2 8-cell embies
BFP #6 - 2/3/13, EDD 10/15/13, DS 9/18/13 at 36w1d
This discussion has been closed.
Re: Adding MTHFR to the diagnosis
that's 100% what I think when I see it... sorry for all your bad news
I'm Homo Motherflucker on the A gene.
Ask your doctor for a RX for Metanx, it's better than Folgard or just super dosing on folic acid as it's essentially a pre-processed version of the B's (MTHFR is essentially the inabilty to process B's). It's also not a bad idea to have your homocyteine & all your B levels checked to see if the MTFHR is actually having an effect on you.
I'm also on the Baby Aspirin and Lovenox regiment
ETA: There's also a fair amount of discussions to whether MTHFR is a viable cause in recurrent loss. But IMO, better safe than sorry. Baby Aspirin & Lovenox also has more benefits than just the blood thinning aspect, so it's a smart protocol when your RPL
BFP#1 10/1/2011. Our perfect little girl, Her heart stopped @ 12w1d. D&E 11/23/11
BFP#2 3/13/12 Weird CP/Possible EP @ 6w0d
BFP#3 5/28/12 CP @ 5w0d
BFP/WTF#4 10/26/12 CP
BFP#5 12/10/12 EDD 8/23/2013
Yep, every time I see it that is what goes through my head. Sorry for all the bad news hon. (((hugs)))
July TTCAL Siggy Challenge - Favorite Children's Book
Surprise BFP 5/15/12, EDD 1/29/13, mm/c @ 8wks, discovered at 11wks, D&C 7/11/12
AF finally arrived on Christmas after 167 days of waiting.
TTA until January 2014
PGAL/PAL always welcome
Thanks, will do!
TTC since April 2010
BFP #1 – March 2011, missed m/c April 2011
BFP #2 – October 2011, m/c November 2011
Surprise BFP #3 – December 2011, diagnosed as cornual, terminated January 2012
BFP #4 – June 2012, m/c July 2012
Diagnosed with bicornuate ute and MTHR gene mutation
BFP #5 – October 2012, missed m/c November 2012
BFP #6 – January 2013, m/c March 2013
No longer TTC. Diagnosis: Hostile ute. Heartbroken and bitter. Pursuing surrogacy.
June 2013 - Carrier found! Could this really happen?!
~All AL always welcome~
Every single time, haha. I think it sounds worse than it actually is, but I'm not an expert in this area by any means. Just want to give you ((hugs)).
BFP#1 April 12, 2011, EDD December 24, 2011, strong heart beat at 7w3d, d&c at 10w6d
BFP#2 Oct 24, 2011, natural miscarriage, EDD unknown
After RPL testing my losses and subsequent infertility are considered unexplained.
Cycle #22: Femara, TI, and progesterone = BFP!!
BFP#3 Dec 21, 2012. Beta #1 @14dpo = 134, progesterone 67.8. Beta #2 @ 17dpo = 664! Team green, EDD 9/1/13, healthy baby boy born 9/12/13!
Congratulations to the fabulous KGS2003! Her sweet boys are here! Grow boys grow!!!
That blows, I'm sorry.
BFP#1 1/31/12, EDD 10/6/12 Harrison Gray born sleeping @ 18w6d. You changed our lives little guy.
BFP#2 EDD 10/29/13, C/P 2/25/13, Bye little Ish, we barely got to know you.
BFP#3 EDD 12/21/13, Baby Boots born 11/23/13 My rainbow baby!
January PAL Siggy Challenge: Good Advice
I'm sorry you got bad news
I always think motherf?cker, and even my RE admitted that he does too!
I have no advice for you, other than to listen to Katharine
TTC since March 2010 ~ Dx Unexplained IF September 2011
2011: IUI + Clomid = CP#1
2012: 3 more IUIs + Clomid = 3 more CPs. One on-our-own pg, also CP
2013: BTB IUI + Lupron/Follistim/Prometrium/PIO = CP #6
IF testing, RPL testing, Autoimmune testing = all normal
So lost.
TTC Since 8/2011
BFP #1 5/13/12 * EDD 1/24/13 * MC at 7 wks 4 days on 6/11/12
BFP #2 5/13/13 * Current EDD 1/23/14
Baby N born 2/8/14
Every time I talk to DH about my diagnosis I call it the mother ***gene! haha! I guess we think alike
So sorry about the diagnosis though
I also have the gene but I have one copy- not sure what kind- when the RE was explaining everything to us my brain was spinning inside my head! I am currently taking baby asprin and when we did the IUI I was on Lovenox injections. GL with everything!
TTC #2 Since October 2011
RE testing results: DH- normal ME- DX:PCOS and One copy of MTHFR gene
IUI#1 Sept/Oct 2012-Follistim, Ovidrel, Metformin, Baby Asprin, Lovenox, Crinone, and Neevo Beta 10/24=BFN
No 2nd IUI but instead TI with Metformin, Baby Asprin, Neevo and Prometrium
BFP #4 5/4/13-EDD 1/19/14- grow little one, grow!
Beta #1@15DPO HCG-95, progesterone-25 Beta #4@24DPO HCG-2498, progesterone-30, 1st U/S 6mm,133BPM 2nd U/S 1.6cm, 167 BPM
Chart
~*~*~*~Everyone Welcome~*~*~*~
I think just about everyone refers to it as mother effer. I found a really great blog about it once, wish I would have bookmarked it.
Apparently mine is the "least worrysome" of the mthfr mutations. My RE recommends a baby aspirin everyday, especially when I'm not ttc. He said with mine it was kind of up to me if I wanted to do baby aspirin when ttc. I'm kind of on the fence about it right now.
My homocysteine levels were slightly elevated, so I do take a b-complex and 1mg extra folic acid daily.
BFP#4 3/17/14 - rainbow Baby BOY arrived 11/10/14 !!
DX: Uterine Septum - Resection 9/5/13 || MTHFR Hetero A1298C || My Chart