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Infertility Veterans
jamielynnohio
member
Follistim and Menopur, what's your opinion?
jamielynnohio
member
I received the rest of my info in the mail yesterday for whenever I decide to cycle.
In going over the protocol changes I had a question... We're keeping the same protocol, but upping my doses. I'll be on 225 follistim/225 menopur adding ganirelix later (not sure dosage). My doc says the amount of meds it takes to stim me is really high. (last time was on 150/150 and had 11 follies at ER) Says it shouldn't take this much for someone of my age; Which is another reason why he thinks I could be DOR despite "normal" AMH/FSH and decent AFC (15 and 11).
What do you think? What are your experiences? Is this a lot? Do you think this shows DOR?
TIA. xoxo
Married '02, TTC May '05
Dx -Ute cancer, DOR from cancer treatments, and embryo quality issues. NOV 2010 CANCER FREE
2005-2011= 3 Rounds of Clomid, 5 IUI's, 3 IVF's- ALL BFN's
After 7yrs TTC, 5yrs of ute cancer, and 11 failed IF treatments, we got a surprise BFP! So thankful!
Gemma Grace born 09/30/12
Phillipians 4:6,7
This discussion has been closed.
Re: Follistim and Menopur, what's your opinion?
i can only tell you my experience, i'm 35 and my FSH is like 6
IVF#1 i did gonal f 150 for 9 nights and (didn't have ER & ET due to failed mTESE) would have had around 18-20 eggs
IVF#1.5 gonal f 150 and menuopor 75 units for 10 nights, 22 eggs, 17 mature
IVF#2 lowered stims and started menopur later and changed protocol around a little and then raised stims (highest being 225 gonal f) 11eggs, 5 mature
IVF#2 protocol was not good for me and my RE and I both agree i need menopur from the beginning.
i have no idea what's right in terms of dosages. how old are you?
Worrying does not empty tomorrow of its troubles, It empties today of its strength. ~Corrie ten Boom
Courage doesn't always roar. Sometimes courage is the little voice at the end of the day that says I'll try again tomorrow. ~Mary Anne Radmacher (thank you beadinglady)
It's been a long journey. TTC since 9/06. multiple IUI's and IVF's and 4 m/c's. IVF#3 = BFP, twins, induced at 34w6d due to baby b passing away (no explanation). Delivered on 35w1d, Baby A - baby girl, and Baby B - baby boy, our little angel.
MTHFR A1298C & C677T, Immune Issues and Factor II
I tested normal on all counts for DOR but my response to meds were horrible. For my first cycle I was on a total of 450iu of a mix of meds (I can't recall which ones as they mixed them up a bit on me each cycle). My last cycle, they upped the dose to 600. I got a total of 6 eggs on the last one.
Poor response to meds can be a sign of DOR.I was given that dx after my first IVF (unexplained before).
Do you know the quality of embryos - as poor quality can also be a determining factor.
After 7 years trying to concieve, 3 failed IUIs and 2 failed IVFs, my third IVF was a success!
My Christmas baby turned into a turkey bird! Dillon Richard was born at 34 weeks, 5 days on November 28, 2009 after 10 weeks on bedrest for preeclampsia.
<a href="http://smg.photobucket.com/albums/v705/arriinthere/PJ/?action=view
27
Dx -Ute cancer, DOR from cancer treatments, and embryo quality issues. NOV 2010 CANCER FREE
2005-2011= 3 Rounds of Clomid, 5 IUI's, 3 IVF's- ALL BFN's
After 7yrs TTC, 5yrs of ute cancer, and 11 failed IF treatments, we got a surprise BFP! So thankful!
Gemma Grace born 09/30/12
Phillipians 4:6,7
I'm on max meds, 450/150, but this time we're doing 300/300.
Whatever it takes!
um- I don't really- I don't think they were good. I mean on day 3 I had a 4 cell grade 2 and one that matured over night that was day 3 a 4 cell grade 3. I have my chart so I can look up and try to understand the reports maybe? I dunno.
Dx -Ute cancer, DOR from cancer treatments, and embryo quality issues. NOV 2010 CANCER FREE
2005-2011= 3 Rounds of Clomid, 5 IUI's, 3 IVF's- ALL BFN's
After 7yrs TTC, 5yrs of ute cancer, and 11 failed IF treatments, we got a surprise BFP! So thankful!
Gemma Grace born 09/30/12
Phillipians 4:6,7
For sure!! Good luck girl!
Dx -Ute cancer, DOR from cancer treatments, and embryo quality issues. NOV 2010 CANCER FREE
2005-2011= 3 Rounds of Clomid, 5 IUI's, 3 IVF's- ALL BFN's
After 7yrs TTC, 5yrs of ute cancer, and 11 failed IF treatments, we got a surprise BFP! So thankful!
Gemma Grace born 09/30/12
Phillipians 4:6,7
I started out at 150/150 too...and that ended up being WAY too much for me. I'm 35 so they figured that was a good place to start. My FSH is 5.4.
I stimmed for 8 days...and i went way too fast. I actually ovualted some of bigger eggs and lost them
I had 11 at ER.
My dose was lowered to 75 follistim then to 50 follistim. Some nites no menopur, or 1/2 or 1.
~SAIF/PAIF/Everyone Welcome~
Me= 37 and DH = 41
Dx: DOR, Endo, APA+ (really high beta 2 glycoprotein antibody and high everything else tested), heterozygous MTHFR mutation, positive for lupus anticoagulant, high FSH, low AMH and both tubes blocked (per HSG on 3/8/11)
IVF #1 - long lupron (with HGH, intralipids, lovenox and BA); 4 retrieved, 3 fertilized; ET 2 blasts and 1 frozen = BFN
IVF #2 - a version of antagonist with EPP (with HGH, intralipids, lovenox and BA); 6 retrieved, 4 mature, 3 fertilized, 2 blasts and 1 frozen blast transferred on day 5 = BFN.
IVF #3 April was postponed to May, May was canceled. June/July was canceled. Had a cyst aspiration and then began IVF #3 in August. ER on 8/22; ET on 8/24 with AH. +HPT on 9/5. Beta #1 (11dpo) = 3; Beta #2 (15dpo) = 29; Beta #3 (17dpo) = 60; Beta #4 (19 dpo) = 118. Heartbeat at 6 weeks 6 days =132. Lil is here!
TTC#2: Trigger + TI = BFN; Clomid + Trigger + IUI = BFN.
IVF #4: BCP + MDLF + Lovenox = 7R, 1F = Transferred 1 6-cell embryo on day 3 = BFN
IVF #5: MDLF + Lovenox = 4R, 1F = Transferred 1 10-cell compacting embryo on day 3 = BFN
IVF #6: (New RE): Long Antagonist November 2014 (transferred two 8 cell grade 1 embryos and froze one blast) = BFN
FET#1: BFN
I was on a higher dosage of Follistim than you but a lower dosage of Menopur.
Had it been up to me I would have preferred to up the Menopur, too.
I haven't been diagnosed as DOR but apparently I have egg quality issues.
TI, IUIs, IVF = c/ps and BFNs
Thnx for the comment. Happy to hear from you Mad!! Missed ya!
Dx -Ute cancer, DOR from cancer treatments, and embryo quality issues. NOV 2010 CANCER FREE
2005-2011= 3 Rounds of Clomid, 5 IUI's, 3 IVF's- ALL BFN's
After 7yrs TTC, 5yrs of ute cancer, and 11 failed IF treatments, we got a surprise BFP! So thankful!
Gemma Grace born 09/30/12
Phillipians 4:6,7
It sounds like my first IVF was exactly the same protocol, but lower doses. I did 150 Follistim, 75 Menopur for 8 days (I'm 28). I only had 9 mature eggs though and only 2 made it to transfer (1 frozen).
For this time around, I'll be on Follistim and Menopur again but higher doses. I'll be on 375iu Follistim and 75iu Menopur. No Ganrilex this time around, stupid Lupron instead. But if it leads to better results (ie pregnancy!), I'll deal with it.
GL with your next cycle!
We also glory in our sufferings, because we know that suffering produces perseverance; perseverance, character; and character, hope. And HOPE does not dissappoint.
Romans 5:3-5
~Matt and Jen~
Married August 26, 2006
TTC since June 2008
Severe MFI
IVF #1 Feb. 2011 = BFN
IVF #2 (Long Lupron) May 2011 = BFP!!!
Our sweet little girl, born January 26, 2012
Time for #2!
IVF #1 (Long Lupron) July 2013 = BFP!!!
Beta #1 (8/1) 203! Beta #2 (8/8) 3,677! 1st u/s scheduled for 8/15!
I never made it to ER, but I was on 450 iu of bravelle per day. I am possible DOR as well, but I didn't make it to ER b/c I was over surpressed.
Good luck with your new protocol!!!