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low morphology-success with ivf/icsi

sassygirljsassygirlj
in Success after IF

Hi Ladies,

My husband had a semen analysis three months ago when going through tests with my obgyn. We were told that everything was within 'normal limits'. We had our first RE visit on Tuesday night and got some shocking news that my husband's morphology was a 0. I have no idea how my obgyn could consider this within normal limits. I am quite livid that I spend the last three months on clomid with her when there is a definate male factor. My dh repeted the analysis on Thursday. We should have the results back on Monday. At our RE visit, we were told if the results come back the same that IVF with ICSI is our best option. My question is has anyone had success stories with such low morphology? It just seems very confusing to me that anything would work if all sperm is abnormal. How could any sperm fertilize an egg if it is abnormal? His numbers were average, motility just shy of 50% so the morph. is the killer.

 Any insight and advice is appreciate. Thank you.

Me-29 PCOS H-29 9/27 Injectables & TI cycle 10/27 Beta #1 120 10/29 Beta #2 301 11/8 5 wks. 4 days-gestational sac and yolk sac located 11/19 7 wks. 1 day-heartbeat found-140bpm! 2/11 19 wks. 4 days-anatomy scan-It's a boy! :)BabyFruit Ticker
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Re: low morphology-success with ivf/icsi

  • DavezWifeDavezWife member

    I wish the search function worked around here  - NEST GODS !!!!!!!!

    There was a decent convo about this last week... I was able to find the link to it, so dig thru this and peek at the links I gave in it... basically even at 0% (as along as it's not ZERO sperm, and all the other numbers are kinda normal) he's still dealing with thousands of sperm that are normal. This thread will explain more.

    Also, not sure if you know, but there's another infertility board here that has many women on it dealing with this, recently renamed "Infertility" and they might be able to offer more ideas too...

    here's the link to our recent disussion...

    basically.. .I say you're not doomed. Good luck !

    https://community.thenest.com/cs/ks/forums/thread/22638565.aspx

     

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  • cheekyalicheekyali
    We have low morph, lowest SA was 3%. We did concieve on our third IUI (I miscarried) and again with IVF and ICSI. I think if your counts and motility are good then even with 0% morph you are still in the game. It just might take several IUIs, so depending on your financial situation/ insurance/ age- it might make more sense to go straigh to IVF. Good luck. And as PP said, the IF board is an awesome bunch of women and many are struggling with the same issue.
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  • RobynKRobynK member

    You are not doomed at all.

    We have SEVERE MFI -- they had DH give 2 samples on ER day because they couldn't find enough swimmers to fertilize my 16 eggs.  He has low unders all around for sperm, really bad.

    IVF with ISCI worked the first time for us!

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  • dtwmcodtwmco
    We have very low morph - did IVF w/ICSI and worked the first try!  Just gotta get those sperm to penetrate the eggs!
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  • melaniescmelaniesc
    We have low morph too, RE said not horrible, but low nonetheless. We had DD with our first IVF with ICSI (after 2 IUIs, one which was a chemical pg).
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  • Babykins11Babykins11
    My DH has 0% morphology and 60% DNA fragmentation (which is where the DNA on the sperm isn't all there).  From my siggy you can see we did IVF w/ICSI and it seems to have worked.  My RE didn't even suggest IUI's as he said the percentage would be so low so we went straight to IVF.
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  • RadlerRadler member
    We had 1 percent normal morphology and had success on our first IVF/ICSI cycle. My clinic said that they have success with 0 percent morph, too. The issue as I understand it is that the oddly-shaped sperm have trouble penetrating the egg, and ICSI bypasses that. Good luck!
    After 7 failed IUIs, IVF w/ ICSI worked!!

    I am thankful every day for my miracle after infertility.

    And thrilled to be pregnant again after FET!

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  • HarleyQ8HarleyQ8

    You are not doomed.  Our morph was low but not 0.  I cant remember how low it was. I can tell you that all of DH's stats were bad and at the last SA before our ivf cycle his count was only 10,000.  So they had to search for good sperm (of which there werent many) out of that small of a sample.  DH was on clomid for a few months but we didnt do a SA after that to see how it improved things.  You can definitley be successful!!!

    You may want to ask your dr about the estrogen priming protocol.  A few of us on here have done it.  It is designed to help you get a higher # of good quality eggs.  I am a firm believer that when there are severe MFI issues you need as many eggs as possible.  Your fertilization rates may not be great (we fertilized 14 out of 28) so you need as many targets as possible, in my humble, non-dr opinion. 

    Wishing you the very best of luck.  Feel free to ask me any questions anytime!

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  • sassygirljsassygirlj

    Ladies,

     I wanted to thank you for you replies. They all have given me hope. My only question is it worth going through IVF with ICSI if all sperm could be abnormal? Do they need some normal sperm to perform this procedure? I just hate to spend all the time and money if the odds are against me. Thanks again!

    Me-29 PCOS H-29 9/27 Injectables & TI cycle 10/27 Beta #1 120 10/29 Beta #2 301 11/8 5 wks. 4 days-gestational sac and yolk sac located 11/19 7 wks. 1 day-heartbeat found-140bpm! 2/11 19 wks. 4 days-anatomy scan-It's a boy! :)BabyFruit Ticker
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  • smilelarismilelari member

    We had low everything including 0% morph and I'm in due October after IVF w/ ICSI

    Abnormally shaped sperm CAN fertilize eggs, even without ICSI

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    ~Working Mom~Breastfeeding Mom~Cloth Diapering Mom~BLW Mom~

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    LO #1 - Took 2 years and 2 IVFs ~ DX - severe MFI mild PCOS homozygous MTHFR (a1298c)
    LO #2 - TTC 7 months, surprise spontaneous BFP!
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