Infertility Veterans

IVF #3, Take 4 :(

I had my baseline yesterday for IVF #3, take 4 and it didn't go well.   I actually thought things might work this time since I started a Provera withdrawal bleed on Tuesday.  But, my lining is still too thick.  No cysts this time, but the bleeding has pretty much stopped and I already have 8 follicles at 10.  So, basically my lining and follicles are out of sync.  No surprise since my last period was just a couple of weeks ago and this bleed was forced by Provera.

I was told to do two Ganirelix injections last night.  Now we wait and see if the bleeding starts back up.  If I don't get more bleeding or if the follicles are already too large by the time it does, I will get canceled again.

Seriously, I really don't think we will ever start IVF #3.  I'm at the point where it seems insane to continue to try.  You know the saying that the definition of insanity is doing the same thing over and over and expecting a different result.  Well, I feel like that is where we are.  I just don't see how things will be different.  But, I'm still praying that something changes between now and Monday and I don't get canceled.  If we get canceled again, I don't know if we will give this a fifth try.

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~SAIF/PAIF/Everyone Welcome~ 

Me= 37 and DH = 41 

Dx: DOR, Endo, APA+ (really high beta 2 glycoprotein antibody and high everything else tested), heterozygous MTHFR mutation, positive for lupus anticoagulant, high FSH, low AMH and both tubes blocked (per HSG on 3/8/11)

IVF #1 - long lupron (with HGH, intralipids, lovenox and BA); 4 retrieved, 3 fertilized; ET 2 blasts and 1 frozen = BFN

IVF #2 - a version of antagonist with EPP (with HGH, intralipids, lovenox and BA); 6 retrieved, 4 mature, 3 fertilized, 2 blasts and 1 frozen blast transferred on day 5 = BFN.

IVF #3 April was postponed to May, May was canceled. June/July was canceled. Had a cyst aspiration and then began IVF #3 in August. ER on 8/22; ET on 8/24 with AH. +HPT on 9/5. Beta #1 (11dpo) = 3; Beta #2 (15dpo) = 29; Beta #3 (17dpo) = 60; Beta #4 (19 dpo) = 118. Heartbeat at 6 weeks 6 days =132.  Lil is here!

TTC#2:  Trigger + TI = BFN; Clomid + Trigger + IUI = BFN.

IVF #4:  BCP + MDLF + Lovenox = 7R, 1F = Transferred 1 6-cell embryo on day 3 = BFN

IVF #5:  MDLF + Lovenox = 4R, 1F = Transferred 1 10-cell compacting embryo on day 3 = BFN

IVF #6:  (New RE):  Long Antagonist November 2014 (transferred two 8 cell grade 1 embryos and froze one blast) = BFN

FET#1:  BFN

Re: IVF #3, Take 4 :(

  • (((hugs)))

    I hope the meds help you and that this time you do get a different result!  Hang in there!

    imageimageimage

    TTC since March 2009 // Me and DH - 28
    Testing Summer/Fall 2010 - Unexplained IF
    IUIs #1-4 ~ Clomid/Ovidrel/TI/IUI ~ all BFNs
    IUI #5 ~ Femara/Ovidrel/TI/IUI ~ BFN
    IUIs #6-9 ~ Research Study Meds/Pregnyl/TI/IUI ~ all BFNs
    IVF Consultation, More Testing
    Diagnostic Cycle ~ Mucinex/Progesterone/TI ~ BFN
    IVF #1 ~ Menopur/Bravelle/Ganirelix/Novarel/Progesterone/Lupron
    7R, 6F // 2 transferred // 3 frosties ~ BFN
    FET #1 ~ Estrace/PIO/Lupron
    3 thawed // 2 transferred // 1 lost // no more frosties ~ BFP!!
    Beta #1 - 456 // Beta #2 - 1176 // Beta #3 - 2933 // Beta #4 - 6753
    EDD: May 16, 2013
    Threatened MC at 6w2d
    Bedrest for SCH // 6w2d through 10w1d
    Elevated TSH and Lazy Thyroid DX @ 10w - Started Synthroid
    Finally released from RE at 13w
    Charles Everett ~ Born 5/20/2013

    Baby Birthday Ticker Ticker


    ~~ My IF Blog ~~ 

  • Oh no, I am so very sorry.  I hope the meds do the trick for you so that you can finally move forward.  IF is so very frustrating.  ::hugs::
    TTC since 3/07. IVF#1 = canceled. IVF#2 = 0% fertilization. IVF#3 = BFN. IVF#4 = c/p.  
    Moving forward with Adoption 2017!
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  • ((huge hugs))  I know you must be beyond frustrated at this point. :(  I'm sooo sorry your body isn't cooperating.  Sending lots of T&Ps that your next check finally reveals some good results! 
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    Baby Birthday Ticker Ticker
    "Now faith is being sure of what we hope for and certain of what we do not see." Hebrews 11:1
  • ::hugs::

    TTC #2 since June '08

    ~*DD 10.21.07*~

    dx unexplained

    IUI #1-4 BFN

    IVF#1 June 2011 BFN

    IVF#2 Dec 2011

    Beta#1 12/21 : 812 Beta#2 12/23 : 1634

    EDD 8/25

    *PAIFW/SAIFW*

  • Sad I'm sorry hun. That is beyond frustrating. I hope that Monday brings good news and you are able to finally start again. (((hugs)))
    DX PCOS w/IR 01/08.
    Currently pg with our 1st after 6.5 yrs of IF (thank you IVF)
     
    My IF/Everything Blog
    There's No Crying in Baseball
    ***My posts are always SAIFW**
  • BIG HUGS

    I am so sorry you are going through this.  I am frustrated for you too!

    I am keeping everything crossed and sending all the vibes I can, so this cycle can finally get moving along!!!!

    TTC #1 Since 11/08 - Dx: MFI & PCOS
    7 IUIs = All BFNs
    2011: March IVF #1.2 = e/p @ 6w: May IVF #2 = BFN: July sFET #1 = BFN

    2012: Jan We're Certified FC/A Parents
    May IVF #3 = c/p
    June-Nov Foster Mommy to M (Toddler)
    July FET #2 = BFN
    Aug FET #3 = BFN
    Sept-Nov Foster Mommy to Baby Bella (Newborn)
    Nov HSG/Sono = Clear!
    Dec FET #4 = BFN

    2013: Feb FET #5 = m/c @ 6.5w
    May-July Foster Mom to H (8 yr old girl)
    June/July/Aug IVF #4 = Freeze All
    July = Unofficially Adopting T (10 yr old boy)
    Sept FET #6 = TBD
    **PAIF/SAIF Welcome**
  • ((Hugs))

    TTC in 2008. Stage II/III endo, Hashimotos hypothyroid, low morph (3%).
    2 cycles Clomid/Ovidrel/TI/Crinone=BFN.
    IUI #1 - 4 Follistim/Ovidrel/IUI/Crinone = BFN.
    IVF #1 - Antagonist w/ ICSI 4/10. 17 retrieved, 5DT of 2, BFN :(
    IVF #2 - Long Lupron w/ ICSI 6/10. 15 retrieved, 3DT of 2, BFFN!!
    Lap 7/21/10
    IVF #3 - Clomid/Antagonist w/ ICSI 10/10. 14 retreived, 3DT of 3, BFP 10/20 but m/c. No HB 11/15/10 - D&C 11/17/10.
    FET - 2 blasts, 1 survived the thaw. Transfer 2/19. Beta #1 3/1 375, Beta #2 3/3 885, Beta #3 3/8 4261, Beta #4 3/11 9005. U/S 3/8 1 sac 1 yolk, U/S 3/16 1 heartbeat 114bpm!

     

    James born Oct. 24th 2011 via c-section at 38 weeks!

    Baby Birthday Ticker Ticker

    Surprise BFP - Jack born April 28, 2013 via VBAC after PTL at 33 1/2 weeks!

    Baby Birthday Ticker Ticker
  • Oh honey, I'm sorry Sad I'm going to pray that Monday brings some good news.
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  • I am so sorry, sweetie, that sounds really frustrating. I'll keep my fingers and toes and everything else crossed for good results on Monday. This will work out, hang in there. Huge (((hugs))).
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  • huge hugs!!!!!!!!! hoping for a change for u soon.
    Married '02, TTC May '05

    Dx -Ute cancer, DOR from cancer treatments, and embryo quality issues. NOV 2010 CANCER FREE
    2005-2011= 3 Rounds of Clomid, 5 IUI's, 3 IVF's- ALL BFN's
    After 7yrs TTC, 5yrs of ute cancer, and 11 failed IF treatments, we got a surprise BFP! So thankful!

    Gemma Grace born 09/30/12

    Phillipians 4:6,7

  • MrsMAFMrsMAF member

    (((HUGS))) I am so sorry hon...I really hope everything pans out and doesn't get cancelled. I'm sure you are just at your wits end at this point.

     

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  • nooooo! I can't believe it :( This is just thinking out loud....but since you have 8 follies that seem to be on track, could you have the ER and freeze embryos until next cycle for transfer? I am keeping my fingers crossed for you hon! Keep us posted. ((hugs))
    TTC since 8/09
    DX: PCO, ENDO, High NK, MTHFR
    8/10 = Lap to remove Endo

    2 Femara TI, 3 Follistim IUI = BFN & 1 c/p
    IVF #1 - BFP - boy/girl Twins!

    Ben and Reese born at 34w2d!
  • ((hugs)) sweetie..
    My Wonderful Sister is my GC!!!! 3 IUIs, 2 unmedicated, 1 50mg of Clomid = All BFNs Next step IVF!!!! Melinda & Michael 5*6*06 God Bless The Broken Road
  • Huge hugs. I'm so sorry to read this. I'm sending tons of T&P with all my might that you don't get cancelled and IVF #3 is your lucky cycle.
    TTC #1 since October 2008. Dealing with MFI.
    IVF #1 w ICSI in July 2010 = BFN
    IVF #2.1 in Oct 2010 converted to IUI = BFN
    IVF #2.2 w ICSI in Dec 2010 = BFN
    Met with new RE in new city on 1/31/11.
    IVF #3 w ICSI in April 2011. HPT on 5/9 = BFP!
    Beta #1 on 5/10 (10dp5dt) = 99.4. Beta #2 on 5/12 = 284. First u/s on 5/26. = Fraternal TWINS!
    Twin boys born & lost on 8/16/11 at 18w1d due to PPROM & preterm labor.
    IVF #4.1 in Jan 2012 converted to IUI on 1/7/12 = BFN
    IVF #4.2 w ICSI in Feb 2012. Lupron on 2/10. Stims on 2/18. ER on 2/29- 7R,6F
    ET scheduled for 3/5/12- nothing to transfer :(
    Dh seeing new MFI uro & Dh starting meds- June 2012.
    IVF #5 in Dec 2012 = BFFN.
    IVF #6 planned for Spring 2013. Praying for our take home baby/ies.
    **P/SAIF and P/SAL always welcome!**

    Lilypie Angel and Memorial tickers
  • Oh nooooo!!  Hon, I am so sorry for all this frustration!  I am beyond pissed for you!  I really hope things turn around and your next appt brings some good news, dammit!!

    Big ((hugs))

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  • (((HUGS))) I'm so sorry, STL. You are so overdue for a break :(
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  • ((big hugs)) I'm so, so sorry it's been dragging on like this!
    Trying to grow our family with both fertility treatments and adoption since March 2009 
    IUIs#1-4 = BFN, IVF#1 = c/p, IVF#2 = OHSS, FET#1=BFP
    BabyFruit Ticker
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  • mm29mm29 member

    (((Hugs)))  I am so sorry! 

    I'm keeping my fingers crossed that things start turning around for you!

    ::: Married June 2003:::
    TTC #1 since: Aug. 2008
    Me: 34, DOR, MTHFR-A1298C (heterozygous), decreased blood flow to uterus, Mild Endo
    DH: 38, Balanced translocation 5&10, unexplained MFI, normal SA and SCSA
    Tx History: IUI 1&2= BFN
    IVF# 1 W/ICSI= BFN
    IVF# 2: cancelled d/t no response
    IVF# 3= 1 egg retrieved=immature/not viable
    IVF# 4= c/p
    ***CCRM ODWU***
    Found DHs BT and Me-decreased blood flow to uterus
    Recommended DE IVF w/PGD, incorporate electro-acupuncture. Decided to cycle locally
    ***New RE***
    DE IVF# 1(cycle #6) w/pgd, (freeze all): 30R, 23M, 15F, slow/poor embryo development, 4 biopsied, 1 Normal "Norm"; DE IVF w/PGD, incorporate electro-acupuncture. 
    IVF# 6: (OE/DS) cancelled
    IVF# 7: (OE/DS) 1R, 1M, 1F, arrested day 5
    Plan-DE IVF# 2 (cycle #8): DE/DS in May 2015


    http://icanhazbabyz.blogspot.com/
    imageimage image 
  • Oh how frustrating! I'm so sorry. T&P that you don't get canceled and can move forward.  Good luck and huge hugs!
    Renee- 37 DH - Chad - 39
    2/06 - surprise pregnancy - twins
    3/06 - m/c 1st baby at 6 weeks 
    5/06 -2nd baby had no heartbeat at 14 wks.
    D&E - Bled out. Blood transfusions. Week in ICU - Cheated Death!
    Diagnosis: Blood clotting and bleeding disorder, immune issues, & cervical stenosis
    5/10 - 1st IVF cycle - BFN
    FET - 10/12/10 - BFN
    1/11 - IVF with PGD - BFN
    IVF - May - BFN
    6/11 New RE - fingers crossed!
    9/11 - IVF - 4 transferred
    10/13 - BFP!!
    It's a boy! Clint Michael, Due in June!!!

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    Baby Birthday Ticker Ticker





  • Oh my goodness...I don't know what to say.  Has birth control ever helped?
    Stopped BCPs December 2008 TTC since June 2009 6 unsuccessful Clomid cycles Dx Annovulatory due to PCOS January 2010 DH-perfect 4 unsuccessful IUIs Began Lupron July 7 for first IVF IVF cancelled; overstimulation and coasting lead to huge drop in E2 New testing with an Endocrinologist...perhaps a new diagnosis... So, not PCOS but Hashimoto's Thyroiditis November 2010 After a looong break, started seeing a new RE. Gearing up for IVF 1.2. Beta 1=197!! BabyFruit Ticker image
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