Trying to Get Pregnant

IF Testing & Treatment w/o 3.14

anniemarie887anniemarie887 member
edited March 2022 in Trying to Get Pregnant
This is a place for those of us who have already started TTC, but have started infertility testing and/or treatments. You can express your thoughts, feelings, and frustrations on infertility. TTC can be a long journey naturally, then add in the difficulties associated with infertility, and it becomes a whole new ballgame. The road to infertility can be lonely, frustrating, and complicated, so let's make this a place where we can vent, ask questions, and support one another. Feel free to resurrect this thread at any point in the week if you have something to say. Treat this as an ongoing conversation.

Diagnosis (if you've been)

Status (WTO/TWW/TTA)

What are you doing this cycle? (Testing? Treatment?)

How are things going?

Any questions?

GTKYWhat are you doing to celebrate St Paddy's day? (sorry if this was already asked, brain is tired! - edited to Paddy b/c apparently Patty is a faux pas!)
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Re: IF Testing & Treatment w/o 3.14

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  • @kiki047 stay tuned for answers to your questions below! But... SO happy you got to see another RE and got such a fresh perspective from her. Haha. I also love that she's obviously not intimidated by your RE. I hope you get some valuable info from this mock cycle and maybe, if you can roll into a transfer in April, we can be transfer buddies! 

    Diagnosis (if you've been): Hashimoto’s, PAI-1 4G/4G mutation, anti-HY immunity, HLA antibodies, high pNK activity, stubborn sperm

    Status (WTO/TWW/TTA): WFAF post mock transfer

    What are you doing this cycle? (Testing? Treatment?): just completed my mock transfer cycle!

    How are things going?: things are going pretty OK. Well, relatively speaking of course. Had my ERA/ReceptivaDx/EMMA/ALICE biopsy test at and while it wasn’t super comfortable, it was better than my HSG which is probably the most painful thing I’ve experienced this far in my TTC journey (@kiki047... so I don't have a a endometrial biopsy to compare to. But I was definitely imagining way worse with this test. TEW showed me the straw she used and it is pretty thin [maybe 2mm] and essentially there's a plunger-like mechanism to get the cells into the tube). I did take Valium + Tylenol 3 30 min before the procedure which I'm sure helped manage the pain. I also can't say my HSG was extremely painful but it _did_ make me tear from the cramping, so that's kind of my gauge of "how painful is this thing?". I hope it helps. 

    Anywho, in the meanwhile, DH and I discussed and instead of rolling right into a transfer prep, we're gonna do a medicated + TI cycle with TEW (going for 4 mature follicles again) because: 1) want to wait for results of the tests before starting a mock transfer; 2) I did get an appointment with Dr. Jubiz (RI) for Mar 23 and I'm hoping I can get more answer about my RI tests. I've realized that the Pregmune report just doesn't cut it for me, so I'm hoping we can dive into the underlying blood results with him; 3) TEW wants me to see a hematologist before my transfer because of my chronically low-than-ref-range platelet counts and also sometimes-low WBC; she's in fact not wanting to use Lovenox because of that, and she also wants to make sure we don't have an underlying problem on our hands that will rear its ugly head in pregnancy; and 4) if we were lucky enough to succeed with first transfer, it would make more sense life / work wise to have a Jan/Feb baby. Plus, doing a medicated cycle means 1) not wasting a cycle; 2) hoping that Prednisone has started to work its magic and could possibly be a differentiator; 3) hoping that the "endometrial scratching" achieved via the biopsy will help get me KU'ed like our girl @inthewoods23!

    Any questions?: I had my E2/P4 tested yesterday, which would ostensibly be "day of transfer" and it came back 642pg/mL and 18.5ng/mL, respectively. For anyone who's gone through a transfer, how does that measure up? 

    GTKY: What are you doing to celebrate St Patty's day? I guess I might wear green if I remember? Lol. MH and I WFH and don't really see anyone, so there's really no point right? I might make a stew though. I do love myself a good stew.

    TTC History
    TTC#2
    Me: 41; MH: 40 | Met 02/2009 | Started Dating 08/2017 | Married 02/02/2020
    Mar 2024 | consult to get established with a new reproductive immunologist (Alan Beer Center)
    Apr/May 2024 | required testing & waiting for a protocol
    May 2024 | protocol given / decided to go back to my old reproductive immunologist, Dr. Jubiz
    Jun / Jul 2024 | more testing, incl. SIS, ultrasound, and endometrial biopsy
    Jul 2024 | Dx chronic endometritis; 14 days of 100mg of doxy given
    Sep 2024 | Repeat endometrial biopsy; still + for chronic endometritis. 2 more antibiotics + an antiviral
    Oct 2024 | Hysteroscopy turned polypectomy; endometriosis consult w/ specialist who confirmed high likelihood of endo based on symptoms and ultrasound; lots of blood tests ordered
    Mar 2025 | Endo excision surgery. Stage 3 endo found! Recoveing
    Apr 2025 | Planning transfer w/ RE & green light protocol w/ RI; target transfer July or August 2025
    May 2025 | Surprise BFP! EDD 1/11/2026


    TTC #1
    Me: 36, MH: 34 | Met 02/2009 | Started Dating 08/2017 | Married 02/02/2020
    TTC #1 02/2020 - 07/2022
    2009 | Dx PCOS; likely a misdiagnosis
    07/14/20 | Dx Hashimoto's Thyroditis
    07/21/20 | 1st RE appointment
    07/2120 - 08/20/20 | so much testing; no signs of PCOS
    08/20/20 | Dx Unexplained; AMA
    09/08/20 | IUI #1 Clomid + Trigger + Prometrium | BFN
    09/30/20 | Urology consult; more testing required
    10/2020 | Clomid + OPK + TI + Prometrium | BFN
    10/26/2020 | Starting 2nd IUI cycle, with Letrazole and with a new RE / different clinic
    11/03/2020 | New Dx "poor egg quality"; IUI cancelled in favor of Trigger + TI + Prometrium | BFN
    11/26/2020 | Combo IUI (Clomid + Menopur) + Trigger + Prometrium | BFN
    12/20/2020 | Combo IUI (Clomid + Gonal-F) + Trigger | IUI Cancelled due to thin lining; TI only | BFN
    01/14/2021 | Combo IUI (Letrazole + Menopur) + Trigger | BFN
    02/06/2021 | Switched to a new RE (TEW) ; trying naturally until we complete additional testing 
    03/14/2021 | Hybrid Double IUI, with Zymot (Letrazole, Gonal-F) + Trigger + Endometrin | Ovulated 4 mature eggs but still a BFN ☹️
    04/07/2021 | Natural cycle while we regroup | BFN
    04/09/2021 | Employer announces fertility benefits starting 05/01/2021! | Search for a new doctor who accepts insurance
    05/10/2021 | New RE consult & plan for IVF
    05/13/2021 | Mid-luteal IVF cycle #1 interrupted; had to get cancer genetic screening done to make sure I didn't have the same SDHA gene mutation as MH. 
    06/10/2021 | Aygestin priming IVF cycle #1; opted to Cx after 9 days of stims since only 5-6/12 follicles responded
    07/26/2021 | Attempt #2 at IVF cycle #1 (mid-luteal start): 8 retrieved, 8 MII, 6 fert (1 PN3), 3 Day 5 & 6 blasts: 3AA, 3AA, 6AB; 3 euploid
    08/09/2021 | Rest cycle / unmedicated TTC | Shockingly, a BFP! EDD: 5/25/202 | CP at 4w4d
    09/23/2021 | IVF cycle #2 (mid-luteal start): 14 retrieved, 13 MII, 11 fert, 5 Day 5 & 6 blasts: 2 x 3AA, 2 x 3AB, 3BB; 2 euploid
    11/12/2021 | IVF cycle #3 (mid-luteal start): cancelled due to ovaries being on vacation
    12/20/2021 | Rest cycle / unmedicated TTC + Pregmune Immunology Testing; BFN
    01/22/2022 | Rest cycle / unmedicated TTC + understanding uncovered immunological issues; BFN
    02/18/2022 | Mock transfer cycle! ERA, ReceptivaDx, EMMA/ALICE; start Prednisone to address NK activity
    03/16/2022 | Final, "Hail Mary" super-ovulation + TI cycle before FET; BFP! EDD: 12/21/2022 | MMC 05/08/2022
    05/20/2022 | D&C; recovering... 
    06/21/2022 | Trying naturally until October 2022
    07/21/2022 | BFP! EDD 04/02/2023; 👦🏼 born on 4/5/2023


  • @acleverusername thanks for the feedback on the biopsy. So sounds like it's pretty standard as far as endometrial biopsies go. This will be my... 6th I think, and only the last one was hit-the-roof-screaming-in-pain kind of awful because it took him 3-4 tries to get a big enough piece to test. Here's hoping that my lining will be niiice and cushy and he won't have to fish around this time. 
    As for your 5dpo BW, none of my clinics test for anything post-transfer so I'm sorry I have nothing to compare that to. 

    TTC History:

    Me: 36  MH: 39, TTC since Dec 2017

    Aug '18: PCOS dx

    Nov '18: MH SA - 19mil

    Dec '18-Mar '19: Letrozole + TI - all BFN

    Apr '19: Letrozole + TI, - BFN.  Repeat SA (27mil) & DNA fragmentation test (17%)

    Aug '19: Letrozole + HCG trigger + IUI + prog supp - BFN (MH: 16mil)

    Sep '19: 2nd IUI, same protocol - BFN (MH: 16mil) 

    Dec '19: IVF #1 w/ICSI, PGT. 5 retrieved, 4 fertilized, 3 blasts, 3 PGT-A normal.

    Mar '20: FET #1, perfect 5AA blast transferred. BFN.

    Sept '20: FET #2, 5BB tsf. 9/18/20 BFP!! EDD: 5/27/21. MMC 11w                                                  

    Feb ‘21: FET #3, last 6BB blast transferred. BFP, EDD 11/2/21. MC 5w3d. 

    May '21: IVF #2 w/ICSI, PGT. 8R, 7M, 6F, 6 blasts - 3AB, 3AB, 3BB, 4BB, 5BB, 6BA. Fresh tsf 5/13/21 - BFN. 

    June '21: PGT-A results = 3 abnormal, 1 low level mosaic. Referred to new REI, had consult with 2nd RE in between. 


    Sept '21: RPL, immune testing normal

    Oct '21: IVF #3 w/IMSI, PGT. 33R, 26M, 23F, 9 blasts (7 day 6, 2 day 7). PGT-A = 5 normal, 1 mosaic

    Dec '21: Positive for endometritis, RX Flagyl & Keflex

    Jan '22: FET #5 - Kitchen sink immune/RIF protocol incl. PRP, intralipids, prednisone, medrol, nivestym, fragmin - CP

    Feb '22: FET #6 - Kitchen sink immune/RIF protocol w/higher doses of pred & fragmin - BFN

    Mar '22: Mock cycle for ERA - cancelled, repeat endometrial biopsy instead. Still positive for endometritis. RX ciprofloxacin & amoxicillin. 

    Apr '22: IVF #4 w/IMSI, PGT. 28R, 23M, 16F, 11 blasts. PGT-A = 6 normal. 

    June '22: FET #7 - Microdose lupron downreg w/kitchen sink immune/RIF protocol - double embryo transfer. BFN.

    July '22: FET #8 - Mini stim w/Puregon + trigger, kitchen sink immune/RIF protocol. BFN. 

    Sep '22: Taking a break

    Dec '22: Attempted abdominal myomectomy, fibroid too close to cervix and major blood vessels. Wasn't removed. 

    Feb '23: FET #9 - Modified natural w/baby asp, HCG trigger, PIO, PRP, Medrol, HCG wash, embryo glue - BFP!! EDD 11/11/23


  • @kiki047 oh man, that seems really confusing to me that two drs with the same practice can have such different philosophies behind care. can you switch to this female RE? or is that not something you are interested in.

    Diagnosis (if you've been): uncooperative uterus aka tbd

    Status (WTO/TWW/TTA): TWW

    What are you doing this cycle? (Testing? Treatment?):  well, we had our RE intake today. i shall spoiler b/c brevity is not my strength and MC talk - and for many of you this like pete and repete sitting on a fence b/c you've been through this...

    • they consider two losses RPL - so cheers to not tormenting women with some arbitrary number of traumatic experiences before seeking addt'l medical intervention.
    • out of the gate she said aneuploidy is the most common reason for RPL - but saw that the karyotyping from my MMC was all normal. talked about how everything could come back "normal" and there are low intervention things they want me doing now like baby aspirin, and a progesterone supplement after ovulation.
    • we've got an initial to do list: karyotyping for us (talked about low odds of translocation but that would mean bypass other options and go to IVF w/genetic testing), additional labs for me to check T3 and T4 (OBGYN only did TSH) and check prolactin, was happy with the start on labs my OBGYN did. call on day 1 of next cycle (which may be thursday, so great timing) and will do pelvic ultrasound and labs for AMH, FSH, and LH sometime day 2-4. then sometime day 6-12 a saline sono. and lastly, a semen analysis for MH.
    • i was relieved that there is no "waiting" i told her AF was due thurs and she was like great, we'll get you in do not worry about us finding the time.
    • she did suggest/explain doing carrier screening for MH and i, explained it was optional. but i figure at this point why not? the diagnostic stuff is covered under my insurance, just not any IUI or IVF .

    How are things going?: exhausted, last week was draining to study and then fail my test. MH is currently negotiating a new job which is exciting but mentally daunting and a big change after 10 yrs. and daylight savings sucks even tho it's only an hour, and i think i am getting ANOTHER cold.

    Any questions?: natm, happy for anyone else's feedback re my intake appt

    GTKYWhat are you doing to celebrate St Paddy's day? (sorry if this was already asked, brain is tired! - edited to Paddy b/c apparently Patty is a faux pas!) i won't do anything thurs, b/c i'm old and work. lol. will manage to wear green. have some fun plans this weekend, the only guinness brewery in the us is in maryland so we'll be heading there friday, i have a friend in town from LA and took the day off.
  • anniemarie887anniemarie887 member
    edited March 2022
    yikes! i def sat on this screen for an hour before i posted and missed @acleverusername i think that sounds like a great plan to make sure you get some more info and feel good going into a FET, but also fingers crossed the stars align on their own!!!

  • Diagnosis (if you've been): PCOS

    Status (WTO/TWW/TTA): technically WTO but really waiting for CD1 to start post BCP

    What are you doing this cycle? (Testing? Treatment?):  Testing is all done so we start with clomid 50mg CD3-7 this cycle finally! We chose the “unmonitored route” which just entails a progesterone test at CD21 to see if the clomid worked. If it doesn’t I’ll likely try 100mg the next cycle 

    How are things going?: I’m anxiously trying to plan this cycle out because DH and I both do shift work and it’s looking like i will be working days and he will be working nights for two critical days when we are supposed to have intercourse so I’m likely going to try and take a last min vacation day or see if someone will switch shifts for me

    Any questions?: anyone find NOT using FF or premom helpful? I’ve downloaded both apps but im a little OCD and I think I may actually be less stressed not tracking and just doing the timed intercourse every other day from CD12-21 lol 

    GTKY: What are you doing to celebrate St Paddy's day? (sorry if this was already asked, brain is tired! - edited to Paddy b/c apparently Patty is a faux pas!) I didn’t even realize it was coming up so soon lol 
  • @kiki047 I hate that some docs are hesitant to order a test just based on their personal beliefs… so I’m really glad you got into the the other one who vouched it! And that you don’t have to wait!

    @acleverusername that’s a lot to unpack this coming cycle for you! Hopefully all goes well! I had a similar experience with my HSG too! And does stew have something to do with st. Paddy’s day that I don’t know about lol?

    @anniemarie887 what test were you studying for!? And what job jump is your parent looking to do!? My husband just made a huge career change so he doesn’t have to travel for work and we are still adjusting but he is enjoying being home! Also so happy no waiting for you too! 
  • Diagnosis (if you've been): RPL, MFI post vasectomy

    Status (WTO/TWW/TTA): WTO 

    What are you doing this cycle? (Testing? Treatment?): Genetic testing is scheduled for Wednesday, after that we shall see

    How are things going?:  I'm irrationally upset that my period started before my genetic testing was done. Which is probably because I'm on my period so FEELINGS! 

    Any questions?: No 

    GTKY: What are you doing to celebrate St Paddy's day? (sorry if this was already asked, brain is tired! - edited to Paddy b/c apparently Patty is a faux pas!) Eating the food. 
    Spoiler for History 

    Me - 30 DH - 32

    April 2009 - 8+ week MC
    January 2012 - BFP - DS Born 10/21/2012
    May 2013 - BFP - Twins MMC @ 13 weeks D&C
    Oct 2013 -  BFP MC @ 6 weeks
    Dec 2013 -  BFP  DD Born 8/16/14 - Cholestasis at 36+5
    Nov 2016 - BFP MC @ 6 weeks
    Dec 2016 - BFP  DD Born 6/19/17 @ 28+4 Severe Pre-E, IUGR, Cholestasis 
    Nov 2017 - BFP MC @ 6 weeks
    Jan 2017 - BFP MC @ 6 weeks
    Jan 2019 - BFP MC @ 6 weeks
    DH Vasectomy Aug 2019
    Feb 2022 - TTC #4 with IVF - RPL testing
    Protein C and S Deficiency - Blood Thinners for Treatment - Maybe we don't know!
    June 2022 - IVF - 2 embryos - 1 transferred 6/22/22 - Transfer Failed
    July 2022 - FET - cancelled
    Dec 2022 - Vasectomy reversal
    June 2023 - DH diagnosed with Brain Tumor - TTC put on indefinite hold
    January 2025 - Surprise BFP! Due 9/13/2025 - CP
    January 2025 - Trying Again



  • *lurking*

    @anniemarie887 mc talk, etc.

    That sounds both very normal and very functional for an RE visit for RPL. I don't think we overlapped a ton, but I also had RPL  "without subfertility" (ie got pregnant relatively easily, did not stay pregnant) and saw the RE, and ended up doing IVF. All of my tests came back normal except for a low AMH, which is correlated with egg quality/aneuploidy.

    One note: carrier screening and karyotyping may be useful to determine whether you want to do IVF (because really the only thing you can do to "treat" them is to biopsy the embryos and test them for the issue). This was also true for my issue, but we were just screening for garden-variety aneuploidy. 

    Anyway, I won't clog up the IF board, but please feel free to PM me if you want to hear anything about my experience. 
    TTC History
    TTC #1 Sep 2017-Sep 2018 
    BFP 11/30/2017 | MMC 12/31/2017
    BFP 6/22/2018 | CP 6/27/2018
    BFP 10/5/2018 | EDD 6/14/2019
    Baby girl born 6/19/19

    TTC #2 May 2020-November 2021
    BFP 7/18/2020 | MonoDi Twins | MMC 9/10/2020
    BFP 11/7/2020 | CP 11/9/2020
    RE Consult January 2021 | Dx "borderline DOR"/RPL
    IVF with PGT:
    Standard Antagonist:
    ER #1 3/27/2021 7R | 5M | 3F | 2B | 1 PGT-A Normal, 1 low-level mosaic
    ER #2 4/22/2021 10R | 7M | 3F | 2B | 0 normal, 2 aneuploid
    ER #3 5/19/2021 2R | 1M | 0F
    Estrogen Priming Antagonist:
    ER #4 7/10/2021 5R | 4M | 3F | 1B | 1 PGT-A Normal
    Duostim  (Standard Antagonist):
    ER #5 9/22/2021 13R | 11M | 8F | 5B | 2 PGT-A Normal, 1 low-level mosaic, 2 aneuploid
    ER #6 10/9/2021  9R | 6M | 4 F | 1B | 1 aneuploid
    FET #1  11/5/2021 | EDD 7/24/2022
    Baby boy born 7/19/22

    TTC #3 since May 2023 (ntnp)
    IVF Started Fall 2023 (Standard Antagonist)
    ER #7 10/6/2023 | 9R | 6M | 5F | 3B | 2 aneuploid, 1 high-level mosaic
    ER #8 10/31/2023 | 5R | 4M | 3F | 1B | 1 PGT-A Normal
    FET #2 11/27/23 | CP (bHCG = 8)
    FET #3 planned Jan 2024



  • @tryingktogku there have been a bunch of ppl who've come through here who've not tracked for sanity. I personally track very little these days... just days I take meds on. If you think it'll be less stress for you not to track, then go for it. I don't even take photos with Premom anymore to track my surge cause I know what a surge looks like. But... I mean... that's after 2+ years of trying. Certainly at the beginning I was really into having ALL OF THE DATA!

    @mambo5-2 your genetic testing doesn't have anything to do with your cycle day, does it? 

    @anniemarie887 general TW for loss + success talk
    Your case is starting to sound a lot like what a member of my fertility therapy group went through: she had an MMC, then a CP. Went for RPL testing, and everything came back normal (except higher FSH). Anyways, she did 2 things in the cycle she was successful: Castor oil packs in the follicular phase, and progesterone in the luteal phase. She successfully carried her 3rd pregnancy to term, and just recently gave birth. I am HOPING that for you it'll be as easy as that. 

    TTC History
    TTC#2
    Me: 41; MH: 40 | Met 02/2009 | Started Dating 08/2017 | Married 02/02/2020
    Mar 2024 | consult to get established with a new reproductive immunologist (Alan Beer Center)
    Apr/May 2024 | required testing & waiting for a protocol
    May 2024 | protocol given / decided to go back to my old reproductive immunologist, Dr. Jubiz
    Jun / Jul 2024 | more testing, incl. SIS, ultrasound, and endometrial biopsy
    Jul 2024 | Dx chronic endometritis; 14 days of 100mg of doxy given
    Sep 2024 | Repeat endometrial biopsy; still + for chronic endometritis. 2 more antibiotics + an antiviral
    Oct 2024 | Hysteroscopy turned polypectomy; endometriosis consult w/ specialist who confirmed high likelihood of endo based on symptoms and ultrasound; lots of blood tests ordered
    Mar 2025 | Endo excision surgery. Stage 3 endo found! Recoveing
    Apr 2025 | Planning transfer w/ RE & green light protocol w/ RI; target transfer July or August 2025
    May 2025 | Surprise BFP! EDD 1/11/2026


    TTC #1
    Me: 36, MH: 34 | Met 02/2009 | Started Dating 08/2017 | Married 02/02/2020
    TTC #1 02/2020 - 07/2022
    2009 | Dx PCOS; likely a misdiagnosis
    07/14/20 | Dx Hashimoto's Thyroditis
    07/21/20 | 1st RE appointment
    07/2120 - 08/20/20 | so much testing; no signs of PCOS
    08/20/20 | Dx Unexplained; AMA
    09/08/20 | IUI #1 Clomid + Trigger + Prometrium | BFN
    09/30/20 | Urology consult; more testing required
    10/2020 | Clomid + OPK + TI + Prometrium | BFN
    10/26/2020 | Starting 2nd IUI cycle, with Letrazole and with a new RE / different clinic
    11/03/2020 | New Dx "poor egg quality"; IUI cancelled in favor of Trigger + TI + Prometrium | BFN
    11/26/2020 | Combo IUI (Clomid + Menopur) + Trigger + Prometrium | BFN
    12/20/2020 | Combo IUI (Clomid + Gonal-F) + Trigger | IUI Cancelled due to thin lining; TI only | BFN
    01/14/2021 | Combo IUI (Letrazole + Menopur) + Trigger | BFN
    02/06/2021 | Switched to a new RE (TEW) ; trying naturally until we complete additional testing 
    03/14/2021 | Hybrid Double IUI, with Zymot (Letrazole, Gonal-F) + Trigger + Endometrin | Ovulated 4 mature eggs but still a BFN ☹️
    04/07/2021 | Natural cycle while we regroup | BFN
    04/09/2021 | Employer announces fertility benefits starting 05/01/2021! | Search for a new doctor who accepts insurance
    05/10/2021 | New RE consult & plan for IVF
    05/13/2021 | Mid-luteal IVF cycle #1 interrupted; had to get cancer genetic screening done to make sure I didn't have the same SDHA gene mutation as MH. 
    06/10/2021 | Aygestin priming IVF cycle #1; opted to Cx after 9 days of stims since only 5-6/12 follicles responded
    07/26/2021 | Attempt #2 at IVF cycle #1 (mid-luteal start): 8 retrieved, 8 MII, 6 fert (1 PN3), 3 Day 5 & 6 blasts: 3AA, 3AA, 6AB; 3 euploid
    08/09/2021 | Rest cycle / unmedicated TTC | Shockingly, a BFP! EDD: 5/25/202 | CP at 4w4d
    09/23/2021 | IVF cycle #2 (mid-luteal start): 14 retrieved, 13 MII, 11 fert, 5 Day 5 & 6 blasts: 2 x 3AA, 2 x 3AB, 3BB; 2 euploid
    11/12/2021 | IVF cycle #3 (mid-luteal start): cancelled due to ovaries being on vacation
    12/20/2021 | Rest cycle / unmedicated TTC + Pregmune Immunology Testing; BFN
    01/22/2022 | Rest cycle / unmedicated TTC + understanding uncovered immunological issues; BFN
    02/18/2022 | Mock transfer cycle! ERA, ReceptivaDx, EMMA/ALICE; start Prednisone to address NK activity
    03/16/2022 | Final, "Hail Mary" super-ovulation + TI cycle before FET; BFP! EDD: 12/21/2022 | MMC 05/08/2022
    05/20/2022 | D&C; recovering... 
    06/21/2022 | Trying naturally until October 2022
    07/21/2022 | BFP! EDD 04/02/2023; 👦🏼 born on 4/5/2023


  • @kiki074 I'm oddly happy that the on call RE was supportive.  I love when doctors made me feel heard and help me know that I am advocating for myself appropriately.  Hopefully your RE gets his poop in a group and does the testing. 

    @acleverusername I really enjoy reading your posts because they are insanely educational for my uneducated self, but it also just hurts my heart that you have that level of experience with IF. I'm coming over for stew on Thursday, just be prepared. 

    @anniemarie887 I hope your insurance doesn't take too long and you can get all the testing done ASAP.

    @tryingktogku I didn't find FF helpful at all.



    Spoiler for History 

    Me - 30 DH - 32

    April 2009 - 8+ week MC
    January 2012 - BFP - DS Born 10/21/2012
    May 2013 - BFP - Twins MMC @ 13 weeks D&C
    Oct 2013 -  BFP MC @ 6 weeks
    Dec 2013 -  BFP  DD Born 8/16/14 - Cholestasis at 36+5
    Nov 2016 - BFP MC @ 6 weeks
    Dec 2016 - BFP  DD Born 6/19/17 @ 28+4 Severe Pre-E, IUGR, Cholestasis 
    Nov 2017 - BFP MC @ 6 weeks
    Jan 2017 - BFP MC @ 6 weeks
    Jan 2019 - BFP MC @ 6 weeks
    DH Vasectomy Aug 2019
    Feb 2022 - TTC #4 with IVF - RPL testing
    Protein C and S Deficiency - Blood Thinners for Treatment - Maybe we don't know!
    June 2022 - IVF - 2 embryos - 1 transferred 6/22/22 - Transfer Failed
    July 2022 - FET - cancelled
    Dec 2022 - Vasectomy reversal
    June 2023 - DH diagnosed with Brain Tumor - TTC put on indefinite hold
    January 2025 - Surprise BFP! Due 9/13/2025 - CP
    January 2025 - Trying Again



  • @acleverusername the genetic testing doesn't have anything to do with my cycle but I have to do a birth control cycle which I am dreading which will now be in April I think depending on how long the genetic testing results take to come back. 
    Spoiler for History 

    Me - 30 DH - 32

    April 2009 - 8+ week MC
    January 2012 - BFP - DS Born 10/21/2012
    May 2013 - BFP - Twins MMC @ 13 weeks D&C
    Oct 2013 -  BFP MC @ 6 weeks
    Dec 2013 -  BFP  DD Born 8/16/14 - Cholestasis at 36+5
    Nov 2016 - BFP MC @ 6 weeks
    Dec 2016 - BFP  DD Born 6/19/17 @ 28+4 Severe Pre-E, IUGR, Cholestasis 
    Nov 2017 - BFP MC @ 6 weeks
    Jan 2017 - BFP MC @ 6 weeks
    Jan 2019 - BFP MC @ 6 weeks
    DH Vasectomy Aug 2019
    Feb 2022 - TTC #4 with IVF - RPL testing
    Protein C and S Deficiency - Blood Thinners for Treatment - Maybe we don't know!
    June 2022 - IVF - 2 embryos - 1 transferred 6/22/22 - Transfer Failed
    July 2022 - FET - cancelled
    Dec 2022 - Vasectomy reversal
    June 2023 - DH diagnosed with Brain Tumor - TTC put on indefinite hold
    January 2025 - Surprise BFP! Due 9/13/2025 - CP
    January 2025 - Trying Again



  • anniemarie887anniemarie887 member
    edited March 2022
    @tryingktogku my series 63. and this will be a huge change for husband, he has been self employed for the last 10 years in the insurance field as an independent appraiser. in the field half the day, home the other half, makes his own schedule. but no retirement, no pto, no benefits. he is staying in the same realm but between working for a high end and large body shop, or 100% remote for a tech company that has gotten into the auto insurance world. it's a great change with room for growth, but will 100% be changing our home life with the fact he is going to have to work 40-50 hours a week. i have to mourn the fact that i will be losing my dinner chef. re FF i do not have the bandwith or restful sleep any longer to BBT, but i use an ava bracelet and FF can adjust for wearable temping. i like data, and the longer i've been ttc the more things i now track  :D
    @mambo5-2 does that timing matter? at my appt today it didn't seem like that testing was cycle day dependent. we do not have to wait for preauths, i have a PPO that i pay an arm and a leg in premium and $5k deductible for. 
    @bumblebee0210 love the gift that is a knowledgeable lurk! and yes, i didn't add in that she said should i have low amh they would recommend going right to IVF at that point. she also said 50% of RPL everything look totally healthy. so ugh.
    @acleverusername you're a gem of a human to wish simplicity to someone else when going through your own path of this. i am very nervous and i know ppl who have been through infinitely worse, but i don't know how my heart can handle another loss.

    eta: fixing spelling and adjusting words. I should not type with a headache… or maybe like I ever. Lol
  • mambo5-2mambo5-2 member
    edited March 2022
    @anniemarie887
    This Genetic testing is the ONLY thing I have had to have pre authed in years!  We have great insurance but they had to determine if I really had RPL, because of standards...
    Spoiler for History 

    Me - 30 DH - 32

    April 2009 - 8+ week MC
    January 2012 - BFP - DS Born 10/21/2012
    May 2013 - BFP - Twins MMC @ 13 weeks D&C
    Oct 2013 -  BFP MC @ 6 weeks
    Dec 2013 -  BFP  DD Born 8/16/14 - Cholestasis at 36+5
    Nov 2016 - BFP MC @ 6 weeks
    Dec 2016 - BFP  DD Born 6/19/17 @ 28+4 Severe Pre-E, IUGR, Cholestasis 
    Nov 2017 - BFP MC @ 6 weeks
    Jan 2017 - BFP MC @ 6 weeks
    Jan 2019 - BFP MC @ 6 weeks
    DH Vasectomy Aug 2019
    Feb 2022 - TTC #4 with IVF - RPL testing
    Protein C and S Deficiency - Blood Thinners for Treatment - Maybe we don't know!
    June 2022 - IVF - 2 embryos - 1 transferred 6/22/22 - Transfer Failed
    July 2022 - FET - cancelled
    Dec 2022 - Vasectomy reversal
    June 2023 - DH diagnosed with Brain Tumor - TTC put on indefinite hold
    January 2025 - Surprise BFP! Due 9/13/2025 - CP
    January 2025 - Trying Again



  • @anniemarie887 oh that’s for security right!? I’m sorry you weren’t successful but if I am correct those tests are super hard no!? And oh I see! Well the benefits do seem to outweigh the cons!? Do you like your abs bracelet! I almost bought one but my wake time varies so much and I don’t sleep well at all so I thought it would likely still be inaccurate for me lo
  • @mambo5-2 oh that’s interesting!
    @tryingktogku yup, for securities. Thanks Dodd Frank act. I’ve had my 6 and SIE for 10ish years, but need this and a series 65. Womp. I love the Ava, I think it needs to get at least 4 hours of sleep? Which is fine for me, my issue comes at like 4-5-6 am when I’m up every hour 🙄. I wound up buying mine secondhand on Facebook marketplace for $125. 
  • @anniemarie887.

    Yeah--- I 100% agree that making women wait for 3 losses before diagnosis is cruel and unusual, but the downside is that actually some reasonable portion of these women actually do just have "bad luck" (the most hated diagnosis in the history of time), and are, all-in-all, fertile women who will go on to have healthy children with or without intervention. I still don't really know if I was in that group or not. Then another set of women are in the "kind of high aneuploidy rate" group, either due to age or AMH, or some unknown thing, and then really it's just IVF with PGT (or trying on your own which will probably work eventually, but maybe with more mcs than is normal or bearable).  And *then* there are women who actually have a clotting issue, or an immunological issue, or a structural issue that is causing the losses of viable fetuses. It's always good to check for these things, because sometimes they are very treatable, but these are the minority for sure. 

    FWIW, our decision about IVF came down more to thinking about whether we might want another child later, and given my high MC rate, my low AMH, and my mom and grandmother going through menopause early, we were worried that even if I was able to get pregnant and carry a baby to term this time, I might not be able to in a few years, so it was as much for fertility preservation as avoiding MC. But we also had really good insurance, so that helped make the decision easier financially. The problem is if you do have low AMH and want to bank embryos, it will likely take a bunch of retrievals, which is neither easy nor cheap! 
    TTC History
    TTC #1 Sep 2017-Sep 2018 
    BFP 11/30/2017 | MMC 12/31/2017
    BFP 6/22/2018 | CP 6/27/2018
    BFP 10/5/2018 | EDD 6/14/2019
    Baby girl born 6/19/19

    TTC #2 May 2020-November 2021
    BFP 7/18/2020 | MonoDi Twins | MMC 9/10/2020
    BFP 11/7/2020 | CP 11/9/2020
    RE Consult January 2021 | Dx "borderline DOR"/RPL
    IVF with PGT:
    Standard Antagonist:
    ER #1 3/27/2021 7R | 5M | 3F | 2B | 1 PGT-A Normal, 1 low-level mosaic
    ER #2 4/22/2021 10R | 7M | 3F | 2B | 0 normal, 2 aneuploid
    ER #3 5/19/2021 2R | 1M | 0F
    Estrogen Priming Antagonist:
    ER #4 7/10/2021 5R | 4M | 3F | 1B | 1 PGT-A Normal
    Duostim  (Standard Antagonist):
    ER #5 9/22/2021 13R | 11M | 8F | 5B | 2 PGT-A Normal, 1 low-level mosaic, 2 aneuploid
    ER #6 10/9/2021  9R | 6M | 4 F | 1B | 1 aneuploid
    FET #1  11/5/2021 | EDD 7/24/2022
    Baby boy born 7/19/22

    TTC #3 since May 2023 (ntnp)
    IVF Started Fall 2023 (Standard Antagonist)
    ER #7 10/6/2023 | 9R | 6M | 5F | 3B | 2 aneuploid, 1 high-level mosaic
    ER #8 10/31/2023 | 5R | 4M | 3F | 1B | 1 PGT-A Normal
    FET #2 11/27/23 | CP (bHCG = 8)
    FET #3 planned Jan 2024



  • anniemarie887anniemarie887 member
    edited March 2022
    @bumblebee0210 thank you, and certainly your decision makes sense and i would do the same!! also, YGPM 

  • @bumblebee0210
     
    I agree with your post 1000% I probably fall into one of those categories but don't know which one.
    Spoiler for History 

    Me - 30 DH - 32

    April 2009 - 8+ week MC
    January 2012 - BFP - DS Born 10/21/2012
    May 2013 - BFP - Twins MMC @ 13 weeks D&C
    Oct 2013 -  BFP MC @ 6 weeks
    Dec 2013 -  BFP  DD Born 8/16/14 - Cholestasis at 36+5
    Nov 2016 - BFP MC @ 6 weeks
    Dec 2016 - BFP  DD Born 6/19/17 @ 28+4 Severe Pre-E, IUGR, Cholestasis 
    Nov 2017 - BFP MC @ 6 weeks
    Jan 2017 - BFP MC @ 6 weeks
    Jan 2019 - BFP MC @ 6 weeks
    DH Vasectomy Aug 2019
    Feb 2022 - TTC #4 with IVF - RPL testing
    Protein C and S Deficiency - Blood Thinners for Treatment - Maybe we don't know!
    June 2022 - IVF - 2 embryos - 1 transferred 6/22/22 - Transfer Failed
    July 2022 - FET - cancelled
    Dec 2022 - Vasectomy reversal
    June 2023 - DH diagnosed with Brain Tumor - TTC put on indefinite hold
    January 2025 - Surprise BFP! Due 9/13/2025 - CP
    January 2025 - Trying Again



  • anniemarie887anniemarie887 member
    edited March 2022
    @optimistgardener i'm sorry your cycle is off, and i know that feeling of being like wtf is going on b/c i'm currently in it this cycle. but more importantly CONGRATULATIONS ON THE JOB!!!!


  • @optimistgardener can we just focus a bit longer on YOU GOT THE JOB!!!!!! OMG. A year ago you were a freelance writer / researcher without any plans to return to academia and now look at you: talking about tenure track and life long pension. You're all grown up! So proud of you girl!!! I know things SUCK BALLS on the TTC front, but I think this key thing falling into place is a good omen for what's to come in the future. So, let's take a moment here and CELEBRATE AF (not Aunt Flo, the other AF)!



    @mambo5-2 makes sense about the genetic testing / bcp stuff. And thank you for your lovely comment about learning from me. I've often said that what good is all the knowledge I've gained from reading the countless PubMed articles, if I don't share it with others. Even though it's not what I do for a living, I'm an academic at heart like Optimist (I come from a long line of academics). Btw, what's really striking about your case is that you seem totally un-phased about IVF. Normally, first-time IVFers to be have SO many questions, but you're like... "all good... I got this." I admire your worry free attitude, whether genuine or faked. 

    @anniemarie887 that is one of the nicest thing someone's said to me. I'm motivated by TEW's mantra "you're gonna be a mother, one way or another" and I truly in my heart believe that for all of us so I try to always look on the bright side for all of us. (I do fail at it sometimes.) 

    @bumblebee0210 your statistician's mind is sorely missed around these parts so please come back and visit often. (Also, I'm saving what you wrote there for future reference/share because it is such a succinctly accurate explanation of the different failures modes in TTC.) 

    TTC History
    TTC#2
    Me: 41; MH: 40 | Met 02/2009 | Started Dating 08/2017 | Married 02/02/2020
    Mar 2024 | consult to get established with a new reproductive immunologist (Alan Beer Center)
    Apr/May 2024 | required testing & waiting for a protocol
    May 2024 | protocol given / decided to go back to my old reproductive immunologist, Dr. Jubiz
    Jun / Jul 2024 | more testing, incl. SIS, ultrasound, and endometrial biopsy
    Jul 2024 | Dx chronic endometritis; 14 days of 100mg of doxy given
    Sep 2024 | Repeat endometrial biopsy; still + for chronic endometritis. 2 more antibiotics + an antiviral
    Oct 2024 | Hysteroscopy turned polypectomy; endometriosis consult w/ specialist who confirmed high likelihood of endo based on symptoms and ultrasound; lots of blood tests ordered
    Mar 2025 | Endo excision surgery. Stage 3 endo found! Recoveing
    Apr 2025 | Planning transfer w/ RE & green light protocol w/ RI; target transfer July or August 2025
    May 2025 | Surprise BFP! EDD 1/11/2026


    TTC #1
    Me: 36, MH: 34 | Met 02/2009 | Started Dating 08/2017 | Married 02/02/2020
    TTC #1 02/2020 - 07/2022
    2009 | Dx PCOS; likely a misdiagnosis
    07/14/20 | Dx Hashimoto's Thyroditis
    07/21/20 | 1st RE appointment
    07/2120 - 08/20/20 | so much testing; no signs of PCOS
    08/20/20 | Dx Unexplained; AMA
    09/08/20 | IUI #1 Clomid + Trigger + Prometrium | BFN
    09/30/20 | Urology consult; more testing required
    10/2020 | Clomid + OPK + TI + Prometrium | BFN
    10/26/2020 | Starting 2nd IUI cycle, with Letrazole and with a new RE / different clinic
    11/03/2020 | New Dx "poor egg quality"; IUI cancelled in favor of Trigger + TI + Prometrium | BFN
    11/26/2020 | Combo IUI (Clomid + Menopur) + Trigger + Prometrium | BFN
    12/20/2020 | Combo IUI (Clomid + Gonal-F) + Trigger | IUI Cancelled due to thin lining; TI only | BFN
    01/14/2021 | Combo IUI (Letrazole + Menopur) + Trigger | BFN
    02/06/2021 | Switched to a new RE (TEW) ; trying naturally until we complete additional testing 
    03/14/2021 | Hybrid Double IUI, with Zymot (Letrazole, Gonal-F) + Trigger + Endometrin | Ovulated 4 mature eggs but still a BFN ☹️
    04/07/2021 | Natural cycle while we regroup | BFN
    04/09/2021 | Employer announces fertility benefits starting 05/01/2021! | Search for a new doctor who accepts insurance
    05/10/2021 | New RE consult & plan for IVF
    05/13/2021 | Mid-luteal IVF cycle #1 interrupted; had to get cancer genetic screening done to make sure I didn't have the same SDHA gene mutation as MH. 
    06/10/2021 | Aygestin priming IVF cycle #1; opted to Cx after 9 days of stims since only 5-6/12 follicles responded
    07/26/2021 | Attempt #2 at IVF cycle #1 (mid-luteal start): 8 retrieved, 8 MII, 6 fert (1 PN3), 3 Day 5 & 6 blasts: 3AA, 3AA, 6AB; 3 euploid
    08/09/2021 | Rest cycle / unmedicated TTC | Shockingly, a BFP! EDD: 5/25/202 | CP at 4w4d
    09/23/2021 | IVF cycle #2 (mid-luteal start): 14 retrieved, 13 MII, 11 fert, 5 Day 5 & 6 blasts: 2 x 3AA, 2 x 3AB, 3BB; 2 euploid
    11/12/2021 | IVF cycle #3 (mid-luteal start): cancelled due to ovaries being on vacation
    12/20/2021 | Rest cycle / unmedicated TTC + Pregmune Immunology Testing; BFN
    01/22/2022 | Rest cycle / unmedicated TTC + understanding uncovered immunological issues; BFN
    02/18/2022 | Mock transfer cycle! ERA, ReceptivaDx, EMMA/ALICE; start Prednisone to address NK activity
    03/16/2022 | Final, "Hail Mary" super-ovulation + TI cycle before FET; BFP! EDD: 12/21/2022 | MMC 05/08/2022
    05/20/2022 | D&C; recovering... 
    06/21/2022 | Trying naturally until October 2022
    07/21/2022 | BFP! EDD 04/02/2023; 👦🏼 born on 4/5/2023


  • @tryingktogku forgot to mention: Traditional Irish Stew is what I'm going for. I feel like it's pretty à propos for St. Paddy's. 

    @optimistgardener: check out this recipe for a Vegetarian version. It actually looks mighty delicious: https://www.food.com/recipe/vegetarian-irish-stew-212784

    TTC History
    TTC#2
    Me: 41; MH: 40 | Met 02/2009 | Started Dating 08/2017 | Married 02/02/2020
    Mar 2024 | consult to get established with a new reproductive immunologist (Alan Beer Center)
    Apr/May 2024 | required testing & waiting for a protocol
    May 2024 | protocol given / decided to go back to my old reproductive immunologist, Dr. Jubiz
    Jun / Jul 2024 | more testing, incl. SIS, ultrasound, and endometrial biopsy
    Jul 2024 | Dx chronic endometritis; 14 days of 100mg of doxy given
    Sep 2024 | Repeat endometrial biopsy; still + for chronic endometritis. 2 more antibiotics + an antiviral
    Oct 2024 | Hysteroscopy turned polypectomy; endometriosis consult w/ specialist who confirmed high likelihood of endo based on symptoms and ultrasound; lots of blood tests ordered
    Mar 2025 | Endo excision surgery. Stage 3 endo found! Recoveing
    Apr 2025 | Planning transfer w/ RE & green light protocol w/ RI; target transfer July or August 2025
    May 2025 | Surprise BFP! EDD 1/11/2026


    TTC #1
    Me: 36, MH: 34 | Met 02/2009 | Started Dating 08/2017 | Married 02/02/2020
    TTC #1 02/2020 - 07/2022
    2009 | Dx PCOS; likely a misdiagnosis
    07/14/20 | Dx Hashimoto's Thyroditis
    07/21/20 | 1st RE appointment
    07/2120 - 08/20/20 | so much testing; no signs of PCOS
    08/20/20 | Dx Unexplained; AMA
    09/08/20 | IUI #1 Clomid + Trigger + Prometrium | BFN
    09/30/20 | Urology consult; more testing required
    10/2020 | Clomid + OPK + TI + Prometrium | BFN
    10/26/2020 | Starting 2nd IUI cycle, with Letrazole and with a new RE / different clinic
    11/03/2020 | New Dx "poor egg quality"; IUI cancelled in favor of Trigger + TI + Prometrium | BFN
    11/26/2020 | Combo IUI (Clomid + Menopur) + Trigger + Prometrium | BFN
    12/20/2020 | Combo IUI (Clomid + Gonal-F) + Trigger | IUI Cancelled due to thin lining; TI only | BFN
    01/14/2021 | Combo IUI (Letrazole + Menopur) + Trigger | BFN
    02/06/2021 | Switched to a new RE (TEW) ; trying naturally until we complete additional testing 
    03/14/2021 | Hybrid Double IUI, with Zymot (Letrazole, Gonal-F) + Trigger + Endometrin | Ovulated 4 mature eggs but still a BFN ☹️
    04/07/2021 | Natural cycle while we regroup | BFN
    04/09/2021 | Employer announces fertility benefits starting 05/01/2021! | Search for a new doctor who accepts insurance
    05/10/2021 | New RE consult & plan for IVF
    05/13/2021 | Mid-luteal IVF cycle #1 interrupted; had to get cancer genetic screening done to make sure I didn't have the same SDHA gene mutation as MH. 
    06/10/2021 | Aygestin priming IVF cycle #1; opted to Cx after 9 days of stims since only 5-6/12 follicles responded
    07/26/2021 | Attempt #2 at IVF cycle #1 (mid-luteal start): 8 retrieved, 8 MII, 6 fert (1 PN3), 3 Day 5 & 6 blasts: 3AA, 3AA, 6AB; 3 euploid
    08/09/2021 | Rest cycle / unmedicated TTC | Shockingly, a BFP! EDD: 5/25/202 | CP at 4w4d
    09/23/2021 | IVF cycle #2 (mid-luteal start): 14 retrieved, 13 MII, 11 fert, 5 Day 5 & 6 blasts: 2 x 3AA, 2 x 3AB, 3BB; 2 euploid
    11/12/2021 | IVF cycle #3 (mid-luteal start): cancelled due to ovaries being on vacation
    12/20/2021 | Rest cycle / unmedicated TTC + Pregmune Immunology Testing; BFN
    01/22/2022 | Rest cycle / unmedicated TTC + understanding uncovered immunological issues; BFN
    02/18/2022 | Mock transfer cycle! ERA, ReceptivaDx, EMMA/ALICE; start Prednisone to address NK activity
    03/16/2022 | Final, "Hail Mary" super-ovulation + TI cycle before FET; BFP! EDD: 12/21/2022 | MMC 05/08/2022
    05/20/2022 | D&C; recovering... 
    06/21/2022 | Trying naturally until October 2022
    07/21/2022 | BFP! EDD 04/02/2023; 👦🏼 born on 4/5/2023


  • @acleverusername
    Oh I am so stressed, but I can't do anything about it at this point and I have started anything really just blood stuff so far. 
    Spoiler for History 

    Me - 30 DH - 32

    April 2009 - 8+ week MC
    January 2012 - BFP - DS Born 10/21/2012
    May 2013 - BFP - Twins MMC @ 13 weeks D&C
    Oct 2013 -  BFP MC @ 6 weeks
    Dec 2013 -  BFP  DD Born 8/16/14 - Cholestasis at 36+5
    Nov 2016 - BFP MC @ 6 weeks
    Dec 2016 - BFP  DD Born 6/19/17 @ 28+4 Severe Pre-E, IUGR, Cholestasis 
    Nov 2017 - BFP MC @ 6 weeks
    Jan 2017 - BFP MC @ 6 weeks
    Jan 2019 - BFP MC @ 6 weeks
    DH Vasectomy Aug 2019
    Feb 2022 - TTC #4 with IVF - RPL testing
    Protein C and S Deficiency - Blood Thinners for Treatment - Maybe we don't know!
    June 2022 - IVF - 2 embryos - 1 transferred 6/22/22 - Transfer Failed
    July 2022 - FET - cancelled
    Dec 2022 - Vasectomy reversal
    June 2023 - DH diagnosed with Brain Tumor - TTC put on indefinite hold
    January 2025 - Surprise BFP! Due 9/13/2025 - CP
    January 2025 - Trying Again



  • @acleverusername oh wow that recipe looks great! i will probably use it as a starting point when i launch my own stew this week sometime. also, thanks for the kind words re: the job. it really is a big deal and feels kind of semi-miraculous. folks who have spent time in academia know that it is rare to walk away from that world and then find a door back in.
    History
    I am doing this on my own. Left ovary and fallopian tube removed due to cyst/necrosis just after birth. Right ovary and tube still purport to function.
    Began TTC in Aug '18 @ age 35
    5 or 6 (or 7?!) cycles using frozen donor sperm, ICI. All BFN
    Mar-Jun '19 IUIs, all BFN
    Began process of referral for RE in spring of '19, blood tests confirm low AMH (.54) but all else is good.
    May '19 HSG shows open tube, but ultrasound suggests fibroids
    MRI in June '19 confirms two large fibroids, one growing through wall of uterus
    In June '19 I move from California to Oregon, disrupting my insurance, referrals, etc. 5 months spent piecing it all back together.
    Nov. '19 attempted myomectomy (vaginal approach) failed. 2nd surgery using laparoscopic method in Jan '20 is successful.
    April '20 --> June '20, natural IUIs, all BFN.
    July? saline ultrasound and bubble test demonstrate open tube
    July '20 clomid cycle cancelled for thin lining
    Aug-Oct, 3 femara cycles, all BFN
    RE referral. While waiting to set up an appointment Nov-Jan,I continue with natural cycles and ICI, using a known donor, BFN...
    Jan '21 more bloodwork, AMH is worse (.30), FSH high albeit not catastrophic at 13.2. hysteroscopy all good. "looks cozy!" says the RE.
    Feb '21, injectables (menopur, novarel), iui, BFN (doc said the frozen donor sperm sample had the "best numbers she'd ever seen!")
    Mar '21, injectables, iui cancelled due to lack of follicles, converted to at home-insem. BFN
    May '21, first IVF round cancelled due to cyst.
    July '21 IVF: standard antagonist. 225menupur/225gonal-f/cetrotide/5000u trigger, AFC 7; 6 days of stims. 8 eggs retrieved, 7 mature, 5 fertilize, 4 made it to blast. 3 are 4AB, 1 is 4BB. PGT-A results all abnormal.
    Oct '21 somewhat improved AMH (.51) and significantly improved FSH (8.9). Maybe it's all the pills I swallow.
    Dec -21, standard antagonist. 225menupur/225gonal-f/cetrotide/5000u trigger, AFC 5; 11 days of stims. retrieval yields 5, 4M, 2 reach day-6 blast (4AB & 4BB). 1 low-level mosaic (chr. 3 deletion), 1 complex abnormal.
    Feb '22 FET (low-level mosaic): CP.
    May '22 egg retrieval, lupron flare protocol. HGH priming for 1 month before stims; md lupron 20/20u daily; menopur 225, follistim 225, 10k trigger after 8 days of stims; AFC 10; 13 retrieved; 10 mature; 8 fertilized. All frozen at 2PN for later thaw, grow, and biopsy.
    July '22 egg retrieval same protocol: 9 days of stims; AFC 8; 10 retrieved, 8 mature, 4 fertilized and frozen.
    Sept '22 ER same protocol: AFC 10; 12 retrieved, 11 mature, 11 fertilized.
    From the 3 retrievals, 7 survived to day 5-6 blastocyst, from which I have 2 normal embryos!
    Jan 20, Fully medicated FET, baby aspirin, dexamethasone, acupuncture, and as much woo as I can stand (which isn't very much). BFN.
    July 23, Natural FET + baby aspirin. BFN.
  • @mambo5-2 well, whenever you feel like you're gonna lose it, we're here for you. :) 

    TTC History
    TTC#2
    Me: 41; MH: 40 | Met 02/2009 | Started Dating 08/2017 | Married 02/02/2020
    Mar 2024 | consult to get established with a new reproductive immunologist (Alan Beer Center)
    Apr/May 2024 | required testing & waiting for a protocol
    May 2024 | protocol given / decided to go back to my old reproductive immunologist, Dr. Jubiz
    Jun / Jul 2024 | more testing, incl. SIS, ultrasound, and endometrial biopsy
    Jul 2024 | Dx chronic endometritis; 14 days of 100mg of doxy given
    Sep 2024 | Repeat endometrial biopsy; still + for chronic endometritis. 2 more antibiotics + an antiviral
    Oct 2024 | Hysteroscopy turned polypectomy; endometriosis consult w/ specialist who confirmed high likelihood of endo based on symptoms and ultrasound; lots of blood tests ordered
    Mar 2025 | Endo excision surgery. Stage 3 endo found! Recoveing
    Apr 2025 | Planning transfer w/ RE & green light protocol w/ RI; target transfer July or August 2025
    May 2025 | Surprise BFP! EDD 1/11/2026


    TTC #1
    Me: 36, MH: 34 | Met 02/2009 | Started Dating 08/2017 | Married 02/02/2020
    TTC #1 02/2020 - 07/2022
    2009 | Dx PCOS; likely a misdiagnosis
    07/14/20 | Dx Hashimoto's Thyroditis
    07/21/20 | 1st RE appointment
    07/2120 - 08/20/20 | so much testing; no signs of PCOS
    08/20/20 | Dx Unexplained; AMA
    09/08/20 | IUI #1 Clomid + Trigger + Prometrium | BFN
    09/30/20 | Urology consult; more testing required
    10/2020 | Clomid + OPK + TI + Prometrium | BFN
    10/26/2020 | Starting 2nd IUI cycle, with Letrazole and with a new RE / different clinic
    11/03/2020 | New Dx "poor egg quality"; IUI cancelled in favor of Trigger + TI + Prometrium | BFN
    11/26/2020 | Combo IUI (Clomid + Menopur) + Trigger + Prometrium | BFN
    12/20/2020 | Combo IUI (Clomid + Gonal-F) + Trigger | IUI Cancelled due to thin lining; TI only | BFN
    01/14/2021 | Combo IUI (Letrazole + Menopur) + Trigger | BFN
    02/06/2021 | Switched to a new RE (TEW) ; trying naturally until we complete additional testing 
    03/14/2021 | Hybrid Double IUI, with Zymot (Letrazole, Gonal-F) + Trigger + Endometrin | Ovulated 4 mature eggs but still a BFN ☹️
    04/07/2021 | Natural cycle while we regroup | BFN
    04/09/2021 | Employer announces fertility benefits starting 05/01/2021! | Search for a new doctor who accepts insurance
    05/10/2021 | New RE consult & plan for IVF
    05/13/2021 | Mid-luteal IVF cycle #1 interrupted; had to get cancer genetic screening done to make sure I didn't have the same SDHA gene mutation as MH. 
    06/10/2021 | Aygestin priming IVF cycle #1; opted to Cx after 9 days of stims since only 5-6/12 follicles responded
    07/26/2021 | Attempt #2 at IVF cycle #1 (mid-luteal start): 8 retrieved, 8 MII, 6 fert (1 PN3), 3 Day 5 & 6 blasts: 3AA, 3AA, 6AB; 3 euploid
    08/09/2021 | Rest cycle / unmedicated TTC | Shockingly, a BFP! EDD: 5/25/202 | CP at 4w4d
    09/23/2021 | IVF cycle #2 (mid-luteal start): 14 retrieved, 13 MII, 11 fert, 5 Day 5 & 6 blasts: 2 x 3AA, 2 x 3AB, 3BB; 2 euploid
    11/12/2021 | IVF cycle #3 (mid-luteal start): cancelled due to ovaries being on vacation
    12/20/2021 | Rest cycle / unmedicated TTC + Pregmune Immunology Testing; BFN
    01/22/2022 | Rest cycle / unmedicated TTC + understanding uncovered immunological issues; BFN
    02/18/2022 | Mock transfer cycle! ERA, ReceptivaDx, EMMA/ALICE; start Prednisone to address NK activity
    03/16/2022 | Final, "Hail Mary" super-ovulation + TI cycle before FET; BFP! EDD: 12/21/2022 | MMC 05/08/2022
    05/20/2022 | D&C; recovering... 
    06/21/2022 | Trying naturally until October 2022
    07/21/2022 | BFP! EDD 04/02/2023; 👦🏼 born on 4/5/2023


  • **lurky lurker**

    @optimistgardener I am SO EXCITED FOR YOU!!!! Congratulations!!!! All the confetti!!!! Academic tenure-track jobs are so rare so WELL DONE TO YOU!!!! 🙌🎉✨

    ::crawls back under my rock::
  • @Paturkey heeeey fellow academic and under-rock denizen. *fist bumps* *scuttles*
    History
    I am doing this on my own. Left ovary and fallopian tube removed due to cyst/necrosis just after birth. Right ovary and tube still purport to function.
    Began TTC in Aug '18 @ age 35
    5 or 6 (or 7?!) cycles using frozen donor sperm, ICI. All BFN
    Mar-Jun '19 IUIs, all BFN
    Began process of referral for RE in spring of '19, blood tests confirm low AMH (.54) but all else is good.
    May '19 HSG shows open tube, but ultrasound suggests fibroids
    MRI in June '19 confirms two large fibroids, one growing through wall of uterus
    In June '19 I move from California to Oregon, disrupting my insurance, referrals, etc. 5 months spent piecing it all back together.
    Nov. '19 attempted myomectomy (vaginal approach) failed. 2nd surgery using laparoscopic method in Jan '20 is successful.
    April '20 --> June '20, natural IUIs, all BFN.
    July? saline ultrasound and bubble test demonstrate open tube
    July '20 clomid cycle cancelled for thin lining
    Aug-Oct, 3 femara cycles, all BFN
    RE referral. While waiting to set up an appointment Nov-Jan,I continue with natural cycles and ICI, using a known donor, BFN...
    Jan '21 more bloodwork, AMH is worse (.30), FSH high albeit not catastrophic at 13.2. hysteroscopy all good. "looks cozy!" says the RE.
    Feb '21, injectables (menopur, novarel), iui, BFN (doc said the frozen donor sperm sample had the "best numbers she'd ever seen!")
    Mar '21, injectables, iui cancelled due to lack of follicles, converted to at home-insem. BFN
    May '21, first IVF round cancelled due to cyst.
    July '21 IVF: standard antagonist. 225menupur/225gonal-f/cetrotide/5000u trigger, AFC 7; 6 days of stims. 8 eggs retrieved, 7 mature, 5 fertilize, 4 made it to blast. 3 are 4AB, 1 is 4BB. PGT-A results all abnormal.
    Oct '21 somewhat improved AMH (.51) and significantly improved FSH (8.9). Maybe it's all the pills I swallow.
    Dec -21, standard antagonist. 225menupur/225gonal-f/cetrotide/5000u trigger, AFC 5; 11 days of stims. retrieval yields 5, 4M, 2 reach day-6 blast (4AB & 4BB). 1 low-level mosaic (chr. 3 deletion), 1 complex abnormal.
    Feb '22 FET (low-level mosaic): CP.
    May '22 egg retrieval, lupron flare protocol. HGH priming for 1 month before stims; md lupron 20/20u daily; menopur 225, follistim 225, 10k trigger after 8 days of stims; AFC 10; 13 retrieved; 10 mature; 8 fertilized. All frozen at 2PN for later thaw, grow, and biopsy.
    July '22 egg retrieval same protocol: 9 days of stims; AFC 8; 10 retrieved, 8 mature, 4 fertilized and frozen.
    Sept '22 ER same protocol: AFC 10; 12 retrieved, 11 mature, 11 fertilized.
    From the 3 retrievals, 7 survived to day 5-6 blastocyst, from which I have 2 normal embryos!
    Jan 20, Fully medicated FET, baby aspirin, dexamethasone, acupuncture, and as much woo as I can stand (which isn't very much). BFN.
    July 23, Natural FET + baby aspirin. BFN.
  • @gingermama29 OMG continuing to be a ginger. Bahahaha. You're a gem. Yes, please DO continue to be a ginger. 

    TTC History
    TTC#2
    Me: 41; MH: 40 | Met 02/2009 | Started Dating 08/2017 | Married 02/02/2020
    Mar 2024 | consult to get established with a new reproductive immunologist (Alan Beer Center)
    Apr/May 2024 | required testing & waiting for a protocol
    May 2024 | protocol given / decided to go back to my old reproductive immunologist, Dr. Jubiz
    Jun / Jul 2024 | more testing, incl. SIS, ultrasound, and endometrial biopsy
    Jul 2024 | Dx chronic endometritis; 14 days of 100mg of doxy given
    Sep 2024 | Repeat endometrial biopsy; still + for chronic endometritis. 2 more antibiotics + an antiviral
    Oct 2024 | Hysteroscopy turned polypectomy; endometriosis consult w/ specialist who confirmed high likelihood of endo based on symptoms and ultrasound; lots of blood tests ordered
    Mar 2025 | Endo excision surgery. Stage 3 endo found! Recoveing
    Apr 2025 | Planning transfer w/ RE & green light protocol w/ RI; target transfer July or August 2025
    May 2025 | Surprise BFP! EDD 1/11/2026


    TTC #1
    Me: 36, MH: 34 | Met 02/2009 | Started Dating 08/2017 | Married 02/02/2020
    TTC #1 02/2020 - 07/2022
    2009 | Dx PCOS; likely a misdiagnosis
    07/14/20 | Dx Hashimoto's Thyroditis
    07/21/20 | 1st RE appointment
    07/2120 - 08/20/20 | so much testing; no signs of PCOS
    08/20/20 | Dx Unexplained; AMA
    09/08/20 | IUI #1 Clomid + Trigger + Prometrium | BFN
    09/30/20 | Urology consult; more testing required
    10/2020 | Clomid + OPK + TI + Prometrium | BFN
    10/26/2020 | Starting 2nd IUI cycle, with Letrazole and with a new RE / different clinic
    11/03/2020 | New Dx "poor egg quality"; IUI cancelled in favor of Trigger + TI + Prometrium | BFN
    11/26/2020 | Combo IUI (Clomid + Menopur) + Trigger + Prometrium | BFN
    12/20/2020 | Combo IUI (Clomid + Gonal-F) + Trigger | IUI Cancelled due to thin lining; TI only | BFN
    01/14/2021 | Combo IUI (Letrazole + Menopur) + Trigger | BFN
    02/06/2021 | Switched to a new RE (TEW) ; trying naturally until we complete additional testing 
    03/14/2021 | Hybrid Double IUI, with Zymot (Letrazole, Gonal-F) + Trigger + Endometrin | Ovulated 4 mature eggs but still a BFN ☹️
    04/07/2021 | Natural cycle while we regroup | BFN
    04/09/2021 | Employer announces fertility benefits starting 05/01/2021! | Search for a new doctor who accepts insurance
    05/10/2021 | New RE consult & plan for IVF
    05/13/2021 | Mid-luteal IVF cycle #1 interrupted; had to get cancer genetic screening done to make sure I didn't have the same SDHA gene mutation as MH. 
    06/10/2021 | Aygestin priming IVF cycle #1; opted to Cx after 9 days of stims since only 5-6/12 follicles responded
    07/26/2021 | Attempt #2 at IVF cycle #1 (mid-luteal start): 8 retrieved, 8 MII, 6 fert (1 PN3), 3 Day 5 & 6 blasts: 3AA, 3AA, 6AB; 3 euploid
    08/09/2021 | Rest cycle / unmedicated TTC | Shockingly, a BFP! EDD: 5/25/202 | CP at 4w4d
    09/23/2021 | IVF cycle #2 (mid-luteal start): 14 retrieved, 13 MII, 11 fert, 5 Day 5 & 6 blasts: 2 x 3AA, 2 x 3AB, 3BB; 2 euploid
    11/12/2021 | IVF cycle #3 (mid-luteal start): cancelled due to ovaries being on vacation
    12/20/2021 | Rest cycle / unmedicated TTC + Pregmune Immunology Testing; BFN
    01/22/2022 | Rest cycle / unmedicated TTC + understanding uncovered immunological issues; BFN
    02/18/2022 | Mock transfer cycle! ERA, ReceptivaDx, EMMA/ALICE; start Prednisone to address NK activity
    03/16/2022 | Final, "Hail Mary" super-ovulation + TI cycle before FET; BFP! EDD: 12/21/2022 | MMC 05/08/2022
    05/20/2022 | D&C; recovering... 
    06/21/2022 | Trying naturally until October 2022
    07/21/2022 | BFP! EDD 04/02/2023; 👦🏼 born on 4/5/2023


  • @gingermama29 another +1 for remaining a ginger, love it. 
  • @gingermama29 omg fingers crossed the trigger is your golden ticket! 
  • @gingermama29 hopefully a trigger and St. Patrick's Day and being a ginger is the perfect combo 
    Spoiler for History 

    Me - 30 DH - 32

    April 2009 - 8+ week MC
    January 2012 - BFP - DS Born 10/21/2012
    May 2013 - BFP - Twins MMC @ 13 weeks D&C
    Oct 2013 -  BFP MC @ 6 weeks
    Dec 2013 -  BFP  DD Born 8/16/14 - Cholestasis at 36+5
    Nov 2016 - BFP MC @ 6 weeks
    Dec 2016 - BFP  DD Born 6/19/17 @ 28+4 Severe Pre-E, IUGR, Cholestasis 
    Nov 2017 - BFP MC @ 6 weeks
    Jan 2017 - BFP MC @ 6 weeks
    Jan 2019 - BFP MC @ 6 weeks
    DH Vasectomy Aug 2019
    Feb 2022 - TTC #4 with IVF - RPL testing
    Protein C and S Deficiency - Blood Thinners for Treatment - Maybe we don't know!
    June 2022 - IVF - 2 embryos - 1 transferred 6/22/22 - Transfer Failed
    July 2022 - FET - cancelled
    Dec 2022 - Vasectomy reversal
    June 2023 - DH diagnosed with Brain Tumor - TTC put on indefinite hold
    January 2025 - Surprise BFP! Due 9/13/2025 - CP
    January 2025 - Trying Again



  • anyone willing to provide any feedback on endometrin vaginal suppositories? started last night... and yikes man, the side effect list looks um.... fun?!
  • @kiki047 HAHAHAAHA my TTC-while-single adventures are getting to you! that whole dream sequence seems weirdly appropriate. also can confirm that the syringe/cupful scenario is really super unhot.
    History
    I am doing this on my own. Left ovary and fallopian tube removed due to cyst/necrosis just after birth. Right ovary and tube still purport to function.
    Began TTC in Aug '18 @ age 35
    5 or 6 (or 7?!) cycles using frozen donor sperm, ICI. All BFN
    Mar-Jun '19 IUIs, all BFN
    Began process of referral for RE in spring of '19, blood tests confirm low AMH (.54) but all else is good.
    May '19 HSG shows open tube, but ultrasound suggests fibroids
    MRI in June '19 confirms two large fibroids, one growing through wall of uterus
    In June '19 I move from California to Oregon, disrupting my insurance, referrals, etc. 5 months spent piecing it all back together.
    Nov. '19 attempted myomectomy (vaginal approach) failed. 2nd surgery using laparoscopic method in Jan '20 is successful.
    April '20 --> June '20, natural IUIs, all BFN.
    July? saline ultrasound and bubble test demonstrate open tube
    July '20 clomid cycle cancelled for thin lining
    Aug-Oct, 3 femara cycles, all BFN
    RE referral. While waiting to set up an appointment Nov-Jan,I continue with natural cycles and ICI, using a known donor, BFN...
    Jan '21 more bloodwork, AMH is worse (.30), FSH high albeit not catastrophic at 13.2. hysteroscopy all good. "looks cozy!" says the RE.
    Feb '21, injectables (menopur, novarel), iui, BFN (doc said the frozen donor sperm sample had the "best numbers she'd ever seen!")
    Mar '21, injectables, iui cancelled due to lack of follicles, converted to at home-insem. BFN
    May '21, first IVF round cancelled due to cyst.
    July '21 IVF: standard antagonist. 225menupur/225gonal-f/cetrotide/5000u trigger, AFC 7; 6 days of stims. 8 eggs retrieved, 7 mature, 5 fertilize, 4 made it to blast. 3 are 4AB, 1 is 4BB. PGT-A results all abnormal.
    Oct '21 somewhat improved AMH (.51) and significantly improved FSH (8.9). Maybe it's all the pills I swallow.
    Dec -21, standard antagonist. 225menupur/225gonal-f/cetrotide/5000u trigger, AFC 5; 11 days of stims. retrieval yields 5, 4M, 2 reach day-6 blast (4AB & 4BB). 1 low-level mosaic (chr. 3 deletion), 1 complex abnormal.
    Feb '22 FET (low-level mosaic): CP.
    May '22 egg retrieval, lupron flare protocol. HGH priming for 1 month before stims; md lupron 20/20u daily; menopur 225, follistim 225, 10k trigger after 8 days of stims; AFC 10; 13 retrieved; 10 mature; 8 fertilized. All frozen at 2PN for later thaw, grow, and biopsy.
    July '22 egg retrieval same protocol: 9 days of stims; AFC 8; 10 retrieved, 8 mature, 4 fertilized and frozen.
    Sept '22 ER same protocol: AFC 10; 12 retrieved, 11 mature, 11 fertilized.
    From the 3 retrievals, 7 survived to day 5-6 blastocyst, from which I have 2 normal embryos!
    Jan 20, Fully medicated FET, baby aspirin, dexamethasone, acupuncture, and as much woo as I can stand (which isn't very much). BFN.
    July 23, Natural FET + baby aspirin. BFN.
  • Genetic Testing labs drawn this morning, 10 vials of blood from me on a fasting blood draw.  I ate a delicious muffin afterwards. Now we wait.  Our genetics lab in town had a major cybersecurity breech awhile back and apparently that means the results are taking FOREVER to get back. I do not want to wait forever.  I am impatient! 

    Also DH had to have his something drawn too, but he only had one vial, how rude. 
    Spoiler for History 

    Me - 30 DH - 32

    April 2009 - 8+ week MC
    January 2012 - BFP - DS Born 10/21/2012
    May 2013 - BFP - Twins MMC @ 13 weeks D&C
    Oct 2013 -  BFP MC @ 6 weeks
    Dec 2013 -  BFP  DD Born 8/16/14 - Cholestasis at 36+5
    Nov 2016 - BFP MC @ 6 weeks
    Dec 2016 - BFP  DD Born 6/19/17 @ 28+4 Severe Pre-E, IUGR, Cholestasis 
    Nov 2017 - BFP MC @ 6 weeks
    Jan 2017 - BFP MC @ 6 weeks
    Jan 2019 - BFP MC @ 6 weeks
    DH Vasectomy Aug 2019
    Feb 2022 - TTC #4 with IVF - RPL testing
    Protein C and S Deficiency - Blood Thinners for Treatment - Maybe we don't know!
    June 2022 - IVF - 2 embryos - 1 transferred 6/22/22 - Transfer Failed
    July 2022 - FET - cancelled
    Dec 2022 - Vasectomy reversal
    June 2023 - DH diagnosed with Brain Tumor - TTC put on indefinite hold
    January 2025 - Surprise BFP! Due 9/13/2025 - CP
    January 2025 - Trying Again



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