Trying to Get Pregnant

Questions/Chart Stalk February 2022



Got questions? Need chart interpretation? Ask away!

Re: Questions/Chart Stalk February 2022

  • edited February 2022
    Okay, ladies, gather round for an epic mystery of "when did Clever ovulate?" 

    So, yeah, I obvi don't make it easy for you, since I don't temp the "normal" way. I wear Oura ring, which gives me a relative reading of my temperatures. I.e. there's a baseline, and when I wake up, I can see if my temperature was below that baseline, or above and by how many degrees. So, I've assigned a random value of 97.5 to that baseline, so if I wake up and see a -0.4, I enter 97.1 into FF. 

    Furthermore, I don't make it easy on you because I don't take photo of my OPKs because after 2+ years of doing so, I know what's a positive OPK. I also stop doing OPKs after I get my first positive. Well.. sometimes I do it for 1 extra day. 

    Here are some other mystery clues of you as you embark on this grand quest to solve "when is O?"

    1. On Wed night, I had 2 glasses of wine, so my temp was slightly elevated. Although, technically, Oura is take surface temp, so it shouldn't be affected by alcohol. At least that's what I'm led to believe. 
    2. For the first time in my life (okay, that's a hyperbole; for the first time since I've been tracking) I had spotting during ovulation. I first saw signs of that on Thu, and also yesterday, and again today. In fact yesterday, the spotting was worthy of a Peggy post with gross photos of what's in my toilet paper. But I decided to spare you. 
    3. This morning I took a Proov test, and it's faint, but it's definitely still negative, indicating that my progesterone is not above the 10mL/IU threshold yet, BUT also confirming ovulation. 
    4. My breasts have been tender since Thu, indicating hormonal rebalancing. 
    5. If I ignore Thu temp, after my 2 glasses of wine, FF says I haven't ovulated yet. 
    6. If I keep Thu temp, FF says I ovulated 3 days ago. 
    7. My first glaringly positive OPK was on Wed. I did test on Tue, and I thought it might be getting darker, but I left it out too long before looking, so I figured I was seeing things because that evening it was definitely still negative. 
    8. My OPK on Thu AM was lighter than Wed, but still positive. 
    Good luck, my fellow detectives. (Need a couple of min to post screen shots from my phone.) 

    If I do discard Thu temp.


    If I don’t discard Thu temp.


    TTC History
    TTC#2
    Me: 41; MH: 40 | Met 02/2009 | Started Dating 08/2017 | Married 02/02/2020
    Mar 2024 | consult to get established with a new reproductive immunologist (Alan Beer Center)
    Apr/May 2024 | required testing & waiting for a protocol
    May 2024 | protocol given / decided to go back to my old reproductive immunologist, Dr. Jubiz
    Jun / Jul 2024 | more testing, incl. SIS, ultrasound, and endometrial biopsy
    Jul 2024 | Dx chronic endometritis; 14 days of 100mg of doxy given
    Sep 2024 | Repeat endometrial biopsy; still + for chronic endometritis. 2 more antibiotics + an antiviral
    Oct 2024... currently awaiting a hysteroscopy (10/28) to check uterine cavity + check for endometritis


    TTC #1
    Me: 36, MH: 34 | Met 02/2009 | Started Dating 08/2017 | Married 02/02/2020
    TTC #1 02/2020 - 07/2022
    2009 | Dx PCOS; likely a misdiagnosis
    07/14/20 | Dx Hashimoto's Thyroditis
    07/21/20 | 1st RE appointment
    07/2120 - 08/20/20 | so much testing; no signs of PCOS
    08/20/20 | Dx Unexplained; AMA
    09/08/20 | IUI #1 Clomid + Trigger + Prometrium | BFN
    09/30/20 | Urology consult; more testing required
    10/2020 | Clomid + OPK + TI + Prometrium | BFN
    10/26/2020 | Starting 2nd IUI cycle, with Letrazole and with a new RE / different clinic
    11/03/2020 | New Dx "poor egg quality"; IUI cancelled in favor of Trigger + TI + Prometrium | BFN
    11/26/2020 | Combo IUI (Clomid + Menopur) + Trigger + Prometrium | BFN
    12/20/2020 | Combo IUI (Clomid + Gonal-F) + Trigger | IUI Cancelled due to thin lining; TI only | BFN
    01/14/2021 | Combo IUI (Letrazole + Menopur) + Trigger | BFN
    02/06/2021 | Switched to a new RE (TEW) ; trying naturally until we complete additional testing 
    03/14/2021 | Hybrid Double IUI, with Zymot (Letrazole, Gonal-F) + Trigger + Endometrin | Ovulated 4 mature eggs but still a BFN ☹️
    04/07/2021 | Natural cycle while we regroup | BFN
    04/09/2021 | Employer announces fertility benefits starting 05/01/2021! | Search for a new doctor who accepts insurance
    05/10/2021 | New RE consult & plan for IVF
    05/13/2021 | Mid-luteal IVF cycle #1 interrupted; had to get cancer genetic screening done to make sure I didn't have the same SDHA gene mutation as MH. 
    06/10/2021 | Aygestin priming IVF cycle #1; opted to Cx after 9 days of stims since only 5-6/12 follicles responded
    07/26/2021 | Attempt #2 at IVF cycle #1 (mid-luteal start): 8 retrieved, 8 MII, 6 fert (1 PN3), 3 Day 5 & 6 blasts: 3AA, 3AA, 6AB; 3 euploid
    08/09/2021 | Rest cycle / unmedicated TTC | Shockingly, a BFP! EDD: 5/25/202 | CP at 4w4d
    09/23/2021 | IVF cycle #2 (mid-luteal start): 14 retrieved, 13 MII, 11 fert, 5 Day 5 & 6 blasts: 2 x 3AA, 2 x 3AB, 3BB; 2 euploid
    11/12/2021 | IVF cycle #3 (mid-luteal start): cancelled due to ovaries being on vacation
    12/20/2021 | Rest cycle / unmedicated TTC + Pregmune Immunology Testing; BFN
    01/22/2022 | Rest cycle / unmedicated TTC + understanding uncovered immunological issues; BFN
    02/18/2022 | Mock transfer cycle! ERA, ReceptivaDx, EMMA/ALICE; start Prednisone to address NK activity
    03/16/2022 | Final, "Hail Mary" super-ovulation + TI cycle before FET; BFP! EDD: 12/21/2022 | MMC 05/08/2022
    05/20/2022 | D&C; recovering... 
    06/21/2022 | Trying naturally until October 2022
    07/21/2022 | BFP! EDD 04/02/2023; 👦🏼 born on 4/5/2023


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  • @acleverusername I vote Thursday purely on the basis of the positive OPK the day before. When all other signs are confusing, I figure it is the most reliable indicator, unless you have lots of evidence in the past of a delayed O after +opk or else a habitually short surge-to-O turnaround.
    History
    I am doing this on my own. Left ovary and fallopian tube removed due to cyst/necrosis just after birth. Right ovary and tube still purport to function.
    Began TTC in Aug '18 @ age 35
    5 or 6 (or 7?!) cycles using frozen donor sperm, ICI. All BFN
    Mar-Jun '19 IUIs, all BFN
    Began process of referral for RE in spring of '19, blood tests confirm low AMH (.54) but all else is good.
    May '19 HSG shows open tube, but ultrasound suggests fibroids
    MRI in June '19 confirms two large fibroids, one growing through wall of uterus
    In June '19 I move from California to Oregon, disrupting my insurance, referrals, etc. 5 months spent piecing it all back together.
    Nov. '19 attempted myomectomy (vaginal approach) failed. 2nd surgery using laparoscopic method in Jan '20 is successful.
    April '20 --> June '20, natural IUIs, all BFN.
    July? saline ultrasound and bubble test demonstrate open tube
    July '20 clomid cycle cancelled for thin lining
    Aug-Oct, 3 femara cycles, all BFN
    RE referral. While waiting to set up an appointment Nov-Jan,I continue with natural cycles and ICI, using a known donor, BFN...
    Jan '21 more bloodwork, AMH is worse (.30), FSH high albeit not catastrophic at 13.2. hysteroscopy all good. "looks cozy!" says the RE.
    Feb '21, injectables (menopur, novarel), iui, BFN (doc said the frozen donor sperm sample had the "best numbers she'd ever seen!")
    Mar '21, injectables, iui cancelled due to lack of follicles, converted to at home-insem. BFN
    May '21, first IVF round cancelled due to cyst.
    July '21 IVF: standard antagonist. 225menupur/225gonal-f/cetrotide/5000u trigger, AFC 7; 6 days of stims. 8 eggs retrieved, 7 mature, 5 fertilize, 4 made it to blast. 3 are 4AB, 1 is 4BB. PGT-A results all abnormal.
    Oct '21 somewhat improved AMH (.51) and significantly improved FSH (8.9). Maybe it's all the pills I swallow.
    Dec -21, standard antagonist. 225menupur/225gonal-f/cetrotide/5000u trigger, AFC 5; 11 days of stims. retrieval yields 5, 4M, 2 reach day-6 blast (4AB & 4BB). 1 low-level mosaic (chr. 3 deletion), 1 complex abnormal.
    Feb '22 FET (low-level mosaic): CP.
    May '22 egg retrieval, lupron flare protocol. HGH priming for 1 month before stims; md lupron 20/20u daily; menopur 225, follistim 225, 10k trigger after 8 days of stims; AFC 10; 13 retrieved; 10 mature; 8 fertilized. All frozen at 2PN for later thaw, grow, and biopsy.
    July '22 egg retrieval same protocol: 9 days of stims; AFC 8; 10 retrieved, 8 mature, 4 fertilized and frozen.
    Sept '22 ER same protocol: AFC 10; 12 retrieved, 11 mature, 11 fertilized.
    From the 3 retrievals, 7 survived to day 5-6 blastocyst, from which I have 2 normal embryos!
    Jan 20, Fully medicated FET, baby aspirin, dexamethasone, acupuncture, and as much woo as I can stand (which isn't very much). BFN.
    July 23, Natural FET + baby aspirin. BFN.
  • @optimistgardener right, so Thu is kind of what I was hoping / thinking. Because a) I definitely ovulated and b) I’m pretty sure I didn’t ovulate on Wed. 

    TTC History
    TTC#2
    Me: 41; MH: 40 | Met 02/2009 | Started Dating 08/2017 | Married 02/02/2020
    Mar 2024 | consult to get established with a new reproductive immunologist (Alan Beer Center)
    Apr/May 2024 | required testing & waiting for a protocol
    May 2024 | protocol given / decided to go back to my old reproductive immunologist, Dr. Jubiz
    Jun / Jul 2024 | more testing, incl. SIS, ultrasound, and endometrial biopsy
    Jul 2024 | Dx chronic endometritis; 14 days of 100mg of doxy given
    Sep 2024 | Repeat endometrial biopsy; still + for chronic endometritis. 2 more antibiotics + an antiviral
    Oct 2024... currently awaiting a hysteroscopy (10/28) to check uterine cavity + check for endometritis


    TTC #1
    Me: 36, MH: 34 | Met 02/2009 | Started Dating 08/2017 | Married 02/02/2020
    TTC #1 02/2020 - 07/2022
    2009 | Dx PCOS; likely a misdiagnosis
    07/14/20 | Dx Hashimoto's Thyroditis
    07/21/20 | 1st RE appointment
    07/2120 - 08/20/20 | so much testing; no signs of PCOS
    08/20/20 | Dx Unexplained; AMA
    09/08/20 | IUI #1 Clomid + Trigger + Prometrium | BFN
    09/30/20 | Urology consult; more testing required
    10/2020 | Clomid + OPK + TI + Prometrium | BFN
    10/26/2020 | Starting 2nd IUI cycle, with Letrazole and with a new RE / different clinic
    11/03/2020 | New Dx "poor egg quality"; IUI cancelled in favor of Trigger + TI + Prometrium | BFN
    11/26/2020 | Combo IUI (Clomid + Menopur) + Trigger + Prometrium | BFN
    12/20/2020 | Combo IUI (Clomid + Gonal-F) + Trigger | IUI Cancelled due to thin lining; TI only | BFN
    01/14/2021 | Combo IUI (Letrazole + Menopur) + Trigger | BFN
    02/06/2021 | Switched to a new RE (TEW) ; trying naturally until we complete additional testing 
    03/14/2021 | Hybrid Double IUI, with Zymot (Letrazole, Gonal-F) + Trigger + Endometrin | Ovulated 4 mature eggs but still a BFN ☹️
    04/07/2021 | Natural cycle while we regroup | BFN
    04/09/2021 | Employer announces fertility benefits starting 05/01/2021! | Search for a new doctor who accepts insurance
    05/10/2021 | New RE consult & plan for IVF
    05/13/2021 | Mid-luteal IVF cycle #1 interrupted; had to get cancer genetic screening done to make sure I didn't have the same SDHA gene mutation as MH. 
    06/10/2021 | Aygestin priming IVF cycle #1; opted to Cx after 9 days of stims since only 5-6/12 follicles responded
    07/26/2021 | Attempt #2 at IVF cycle #1 (mid-luteal start): 8 retrieved, 8 MII, 6 fert (1 PN3), 3 Day 5 & 6 blasts: 3AA, 3AA, 6AB; 3 euploid
    08/09/2021 | Rest cycle / unmedicated TTC | Shockingly, a BFP! EDD: 5/25/202 | CP at 4w4d
    09/23/2021 | IVF cycle #2 (mid-luteal start): 14 retrieved, 13 MII, 11 fert, 5 Day 5 & 6 blasts: 2 x 3AA, 2 x 3AB, 3BB; 2 euploid
    11/12/2021 | IVF cycle #3 (mid-luteal start): cancelled due to ovaries being on vacation
    12/20/2021 | Rest cycle / unmedicated TTC + Pregmune Immunology Testing; BFN
    01/22/2022 | Rest cycle / unmedicated TTC + understanding uncovered immunological issues; BFN
    02/18/2022 | Mock transfer cycle! ERA, ReceptivaDx, EMMA/ALICE; start Prednisone to address NK activity
    03/16/2022 | Final, "Hail Mary" super-ovulation + TI cycle before FET; BFP! EDD: 12/21/2022 | MMC 05/08/2022
    05/20/2022 | D&C; recovering... 
    06/21/2022 | Trying naturally until October 2022
    07/21/2022 | BFP! EDD 04/02/2023; 👦🏼 born on 4/5/2023


  • edited February 2022
    So I changed my detector from Advanced to OPK/Monitor and it confirms O on Thu. So I’ll just go with that. 



    TTC History
    TTC#2
    Me: 41; MH: 40 | Met 02/2009 | Started Dating 08/2017 | Married 02/02/2020
    Mar 2024 | consult to get established with a new reproductive immunologist (Alan Beer Center)
    Apr/May 2024 | required testing & waiting for a protocol
    May 2024 | protocol given / decided to go back to my old reproductive immunologist, Dr. Jubiz
    Jun / Jul 2024 | more testing, incl. SIS, ultrasound, and endometrial biopsy
    Jul 2024 | Dx chronic endometritis; 14 days of 100mg of doxy given
    Sep 2024 | Repeat endometrial biopsy; still + for chronic endometritis. 2 more antibiotics + an antiviral
    Oct 2024... currently awaiting a hysteroscopy (10/28) to check uterine cavity + check for endometritis


    TTC #1
    Me: 36, MH: 34 | Met 02/2009 | Started Dating 08/2017 | Married 02/02/2020
    TTC #1 02/2020 - 07/2022
    2009 | Dx PCOS; likely a misdiagnosis
    07/14/20 | Dx Hashimoto's Thyroditis
    07/21/20 | 1st RE appointment
    07/2120 - 08/20/20 | so much testing; no signs of PCOS
    08/20/20 | Dx Unexplained; AMA
    09/08/20 | IUI #1 Clomid + Trigger + Prometrium | BFN
    09/30/20 | Urology consult; more testing required
    10/2020 | Clomid + OPK + TI + Prometrium | BFN
    10/26/2020 | Starting 2nd IUI cycle, with Letrazole and with a new RE / different clinic
    11/03/2020 | New Dx "poor egg quality"; IUI cancelled in favor of Trigger + TI + Prometrium | BFN
    11/26/2020 | Combo IUI (Clomid + Menopur) + Trigger + Prometrium | BFN
    12/20/2020 | Combo IUI (Clomid + Gonal-F) + Trigger | IUI Cancelled due to thin lining; TI only | BFN
    01/14/2021 | Combo IUI (Letrazole + Menopur) + Trigger | BFN
    02/06/2021 | Switched to a new RE (TEW) ; trying naturally until we complete additional testing 
    03/14/2021 | Hybrid Double IUI, with Zymot (Letrazole, Gonal-F) + Trigger + Endometrin | Ovulated 4 mature eggs but still a BFN ☹️
    04/07/2021 | Natural cycle while we regroup | BFN
    04/09/2021 | Employer announces fertility benefits starting 05/01/2021! | Search for a new doctor who accepts insurance
    05/10/2021 | New RE consult & plan for IVF
    05/13/2021 | Mid-luteal IVF cycle #1 interrupted; had to get cancer genetic screening done to make sure I didn't have the same SDHA gene mutation as MH. 
    06/10/2021 | Aygestin priming IVF cycle #1; opted to Cx after 9 days of stims since only 5-6/12 follicles responded
    07/26/2021 | Attempt #2 at IVF cycle #1 (mid-luteal start): 8 retrieved, 8 MII, 6 fert (1 PN3), 3 Day 5 & 6 blasts: 3AA, 3AA, 6AB; 3 euploid
    08/09/2021 | Rest cycle / unmedicated TTC | Shockingly, a BFP! EDD: 5/25/202 | CP at 4w4d
    09/23/2021 | IVF cycle #2 (mid-luteal start): 14 retrieved, 13 MII, 11 fert, 5 Day 5 & 6 blasts: 2 x 3AA, 2 x 3AB, 3BB; 2 euploid
    11/12/2021 | IVF cycle #3 (mid-luteal start): cancelled due to ovaries being on vacation
    12/20/2021 | Rest cycle / unmedicated TTC + Pregmune Immunology Testing; BFN
    01/22/2022 | Rest cycle / unmedicated TTC + understanding uncovered immunological issues; BFN
    02/18/2022 | Mock transfer cycle! ERA, ReceptivaDx, EMMA/ALICE; start Prednisone to address NK activity
    03/16/2022 | Final, "Hail Mary" super-ovulation + TI cycle before FET; BFP! EDD: 12/21/2022 | MMC 05/08/2022
    05/20/2022 | D&C; recovering... 
    06/21/2022 | Trying naturally until October 2022
    07/21/2022 | BFP! EDD 04/02/2023; 👦🏼 born on 4/5/2023


  • Has anyone had any experience with hydrosalpinx?
  • edited February 2022
    hi @jb129 welcome and thanks for posting in our questions thread! there may be people on this board who have dealt with hydrosalpinx or other issues related to infection/scarring/irritation who can weigh in. I have not had this diagnosis and can only speak to the details you provided in your original posting (the one-off).
    (i'm spoilering a cut/paste version here in case others want to refer to it)
    I may have hydropsalpinx on my right fallopian tube. I have yet to get an HSG, but based on the ultrasound images, it's pretty certain. They believe it might've been a result of my previous ovarian cyst surgery; perhaps my body is just prone to scarring which resulted in hydropsalpinx.

    I think the fallopian tube in question may need to be removed. My doctor didn't necessarily tell me to stop TTC. What she did say is that - I need to call her right away if we found out we were pregnant so they can make sure it isn't a tubal pregnancy.

    But aren't the risks higher that way? eg, potential miscarriages if fluid leaks into uterus, ectopic pregnancy. It looks like the body will need a much longer recovery vs just removing the tubes via laparoscopy and TTCing again?

    If pregnancy were established, can hydropsalpinx still prevent that from becoming full-term? Or is hydropsalpinx only an issue with implantation?

    it sounds like you're still waiting for further examination before they make a definitive diagnosis. you may, unfortunately, need to be patient for a while until they can better visualize what's going on with the tube. once the doctor has all the information from the various visualizing methods, they'll be able to offer you better guidance as to the most appropriate treatment. from what i have read, doctors will often remove a fallopian tube and then may encourage patients to consider ivf, since having only one tube but two ovaries still firing away will reduce your changes on a per cycle basis. However, I cannot say for sure if this is what your doctors would recommend.

    I also can't speak to whether the risks are higher for a pregnancy conceived while dealing with hydrosalpinx. You'll want to talk this over with your provider! But it sounds like you may be leaning towards getting the surgery done before you continue your ttc journey, regardless. If so, please ask your doctor to talk more with you about what your ttc process would look like after the surgery. Would they consider you a good candidate for the "old fashioned" method of timed intercourse? or would they want you to do monitored cycles and an IUI when the correct ovary is ready to ovulate? Or just go straight to IVF? These are big questions and may have insurance/life plans/invasive treatment aspects about them for you to consider.


    History
    I am doing this on my own. Left ovary and fallopian tube removed due to cyst/necrosis just after birth. Right ovary and tube still purport to function.
    Began TTC in Aug '18 @ age 35
    5 or 6 (or 7?!) cycles using frozen donor sperm, ICI. All BFN
    Mar-Jun '19 IUIs, all BFN
    Began process of referral for RE in spring of '19, blood tests confirm low AMH (.54) but all else is good.
    May '19 HSG shows open tube, but ultrasound suggests fibroids
    MRI in June '19 confirms two large fibroids, one growing through wall of uterus
    In June '19 I move from California to Oregon, disrupting my insurance, referrals, etc. 5 months spent piecing it all back together.
    Nov. '19 attempted myomectomy (vaginal approach) failed. 2nd surgery using laparoscopic method in Jan '20 is successful.
    April '20 --> June '20, natural IUIs, all BFN.
    July? saline ultrasound and bubble test demonstrate open tube
    July '20 clomid cycle cancelled for thin lining
    Aug-Oct, 3 femara cycles, all BFN
    RE referral. While waiting to set up an appointment Nov-Jan,I continue with natural cycles and ICI, using a known donor, BFN...
    Jan '21 more bloodwork, AMH is worse (.30), FSH high albeit not catastrophic at 13.2. hysteroscopy all good. "looks cozy!" says the RE.
    Feb '21, injectables (menopur, novarel), iui, BFN (doc said the frozen donor sperm sample had the "best numbers she'd ever seen!")
    Mar '21, injectables, iui cancelled due to lack of follicles, converted to at home-insem. BFN
    May '21, first IVF round cancelled due to cyst.
    July '21 IVF: standard antagonist. 225menupur/225gonal-f/cetrotide/5000u trigger, AFC 7; 6 days of stims. 8 eggs retrieved, 7 mature, 5 fertilize, 4 made it to blast. 3 are 4AB, 1 is 4BB. PGT-A results all abnormal.
    Oct '21 somewhat improved AMH (.51) and significantly improved FSH (8.9). Maybe it's all the pills I swallow.
    Dec -21, standard antagonist. 225menupur/225gonal-f/cetrotide/5000u trigger, AFC 5; 11 days of stims. retrieval yields 5, 4M, 2 reach day-6 blast (4AB & 4BB). 1 low-level mosaic (chr. 3 deletion), 1 complex abnormal.
    Feb '22 FET (low-level mosaic): CP.
    May '22 egg retrieval, lupron flare protocol. HGH priming for 1 month before stims; md lupron 20/20u daily; menopur 225, follistim 225, 10k trigger after 8 days of stims; AFC 10; 13 retrieved; 10 mature; 8 fertilized. All frozen at 2PN for later thaw, grow, and biopsy.
    July '22 egg retrieval same protocol: 9 days of stims; AFC 8; 10 retrieved, 8 mature, 4 fertilized and frozen.
    Sept '22 ER same protocol: AFC 10; 12 retrieved, 11 mature, 11 fertilized.
    From the 3 retrievals, 7 survived to day 5-6 blastocyst, from which I have 2 normal embryos!
    Jan 20, Fully medicated FET, baby aspirin, dexamethasone, acupuncture, and as much woo as I can stand (which isn't very much). BFN.
    July 23, Natural FET + baby aspirin. BFN.
  • @acleverusername it's been a while since I had to decode a chart but I'd be inclined to agree with @optimistgardener and FF, Thurs looks plausible to me as well. 

    @jb129 I'm sorry, I don't have any personal experience with hydrosalpinx but I do hope you find some answers. I agree that further diagnostic testing is required, the HSG at the very least, possibly an MRI to get a better look at it if they don't recommend a laparascopy. If it's just a fluid buildup, I read that can sometimes be caused by an infection which could be treated with antibiotics, so it could go either way at this point. Have they scheduled an HSG for you yet? 

    TTC History:

    Me: 36  MH: 39, TTC since Dec 2017

    Aug '18: PCOS dx

    Nov '18: MH SA - 19mil

    Dec '18-Mar '19: Letrozole + TI - all BFN

    Apr '19: Letrozole + TI, - BFN.  Repeat SA (27mil) & DNA fragmentation test (17%)

    Aug '19: Letrozole + HCG trigger + IUI + prog supp - BFN (MH: 16mil)

    Sep '19: 2nd IUI, same protocol - BFN (MH: 16mil) 

    Dec '19: IVF #1 w/ICSI, PGT. 5 retrieved, 4 fertilized, 3 blasts, 3 PGT-A normal.

    Mar '20: FET #1, perfect 5AA blast transferred. BFN.

    Sept '20: FET #2, 5BB tsf. 9/18/20 BFP!! EDD: 5/27/21. MMC 11w                                                  

    Feb ‘21: FET #3, last 6BB blast transferred. BFP, EDD 11/2/21. MC 5w3d. 

    May '21: IVF #2 w/ICSI, PGT. 8R, 7M, 6F, 6 blasts - 3AB, 3AB, 3BB, 4BB, 5BB, 6BA. Fresh tsf 5/13/21 - BFN. 

    June '21: PGT-A results = 3 abnormal, 1 low level mosaic. Referred to new REI, had consult with 2nd RE in between. 


    Sept '21: RPL, immune testing normal

    Oct '21: IVF #3 w/IMSI, PGT. 33R, 26M, 23F, 9 blasts (7 day 6, 2 day 7). PGT-A = 5 normal, 1 mosaic

    Dec '21: Positive for endometritis, RX Flagyl & Keflex

    Jan '22: FET #5 - Kitchen sink immune/RIF protocol incl. PRP, intralipids, prednisone, medrol, nivestym, fragmin - CP

    Feb '22: FET #6 - Kitchen sink immune/RIF protocol w/higher doses of pred & fragmin - BFN

    Mar '22: Mock cycle for ERA - cancelled, repeat endometrial biopsy instead. Still positive for endometritis. RX ciprofloxacin & amoxicillin. 

    Apr '22: IVF #4 w/IMSI, PGT. 28R, 23M, 16F, 11 blasts. PGT-A = 6 normal. 

    June '22: FET #7 - Microdose lupron downreg w/kitchen sink immune/RIF protocol - double embryo transfer. BFN.

    July '22: FET #8 - Mini stim w/Puregon + trigger, kitchen sink immune/RIF protocol. BFN. 

    Sep '22: Taking a break

    Dec '22: Attempted abdominal myomectomy, fibroid too close to cervix and major blood vessels. Wasn't removed. 

    Feb '23: FET #9 - Modified natural w/baby asp, HCG trigger, PIO, PRP, Medrol, HCG wash, embryo glue - BFP!! EDD 11/11/23


  • I've put my CD3 bloodwork results into the spoiler below. Any thoughts as to what I might hear for next steps? I have an appointment Wednesday to go over the results with my midwife, but I appreciate any insights about what I might expect. 

    FSH 7.4 

    LH 5.7

    Estradiol 27.6


    Google suggests FSH is normal for my age (36) and LH is within normal range. Estradiol seems low by my Googling.

  • @abjm0325 those numbers look good to me. A low E2 on Day 3 is actually good. It's a high E2 that you don't want to see. Overall, I think you're in fine shape. Did they test anything else? I.e. Prolactin? Thyroid? 

    TTC History
    TTC#2
    Me: 41; MH: 40 | Met 02/2009 | Started Dating 08/2017 | Married 02/02/2020
    Mar 2024 | consult to get established with a new reproductive immunologist (Alan Beer Center)
    Apr/May 2024 | required testing & waiting for a protocol
    May 2024 | protocol given / decided to go back to my old reproductive immunologist, Dr. Jubiz
    Jun / Jul 2024 | more testing, incl. SIS, ultrasound, and endometrial biopsy
    Jul 2024 | Dx chronic endometritis; 14 days of 100mg of doxy given
    Sep 2024 | Repeat endometrial biopsy; still + for chronic endometritis. 2 more antibiotics + an antiviral
    Oct 2024... currently awaiting a hysteroscopy (10/28) to check uterine cavity + check for endometritis


    TTC #1
    Me: 36, MH: 34 | Met 02/2009 | Started Dating 08/2017 | Married 02/02/2020
    TTC #1 02/2020 - 07/2022
    2009 | Dx PCOS; likely a misdiagnosis
    07/14/20 | Dx Hashimoto's Thyroditis
    07/21/20 | 1st RE appointment
    07/2120 - 08/20/20 | so much testing; no signs of PCOS
    08/20/20 | Dx Unexplained; AMA
    09/08/20 | IUI #1 Clomid + Trigger + Prometrium | BFN
    09/30/20 | Urology consult; more testing required
    10/2020 | Clomid + OPK + TI + Prometrium | BFN
    10/26/2020 | Starting 2nd IUI cycle, with Letrazole and with a new RE / different clinic
    11/03/2020 | New Dx "poor egg quality"; IUI cancelled in favor of Trigger + TI + Prometrium | BFN
    11/26/2020 | Combo IUI (Clomid + Menopur) + Trigger + Prometrium | BFN
    12/20/2020 | Combo IUI (Clomid + Gonal-F) + Trigger | IUI Cancelled due to thin lining; TI only | BFN
    01/14/2021 | Combo IUI (Letrazole + Menopur) + Trigger | BFN
    02/06/2021 | Switched to a new RE (TEW) ; trying naturally until we complete additional testing 
    03/14/2021 | Hybrid Double IUI, with Zymot (Letrazole, Gonal-F) + Trigger + Endometrin | Ovulated 4 mature eggs but still a BFN ☹️
    04/07/2021 | Natural cycle while we regroup | BFN
    04/09/2021 | Employer announces fertility benefits starting 05/01/2021! | Search for a new doctor who accepts insurance
    05/10/2021 | New RE consult & plan for IVF
    05/13/2021 | Mid-luteal IVF cycle #1 interrupted; had to get cancer genetic screening done to make sure I didn't have the same SDHA gene mutation as MH. 
    06/10/2021 | Aygestin priming IVF cycle #1; opted to Cx after 9 days of stims since only 5-6/12 follicles responded
    07/26/2021 | Attempt #2 at IVF cycle #1 (mid-luteal start): 8 retrieved, 8 MII, 6 fert (1 PN3), 3 Day 5 & 6 blasts: 3AA, 3AA, 6AB; 3 euploid
    08/09/2021 | Rest cycle / unmedicated TTC | Shockingly, a BFP! EDD: 5/25/202 | CP at 4w4d
    09/23/2021 | IVF cycle #2 (mid-luteal start): 14 retrieved, 13 MII, 11 fert, 5 Day 5 & 6 blasts: 2 x 3AA, 2 x 3AB, 3BB; 2 euploid
    11/12/2021 | IVF cycle #3 (mid-luteal start): cancelled due to ovaries being on vacation
    12/20/2021 | Rest cycle / unmedicated TTC + Pregmune Immunology Testing; BFN
    01/22/2022 | Rest cycle / unmedicated TTC + understanding uncovered immunological issues; BFN
    02/18/2022 | Mock transfer cycle! ERA, ReceptivaDx, EMMA/ALICE; start Prednisone to address NK activity
    03/16/2022 | Final, "Hail Mary" super-ovulation + TI cycle before FET; BFP! EDD: 12/21/2022 | MMC 05/08/2022
    05/20/2022 | D&C; recovering... 
    06/21/2022 | Trying naturally until October 2022
    07/21/2022 | BFP! EDD 04/02/2023; 👦🏼 born on 4/5/2023


  • @acleverusername Ah, see this is why I should not be trusted to do my own Googling. Thank you for setting me straight on the E2. This was the only testing they did last week. When I meet with the midwife on Wednesday we will be discussing my previous thyroid result too to see if they want to do a full thyroid panel or what they recommend. Is Prolactin something I should push to be tested for next? 
  • @abjm0325 definitely get your prolactin checked, as well as getting that thyroid panel (TSH, T3, T4 + antibodies panel). Also ask to get your androgens tested: testosterone, DHEA, SHBG. 

    TTC History
    TTC#2
    Me: 41; MH: 40 | Met 02/2009 | Started Dating 08/2017 | Married 02/02/2020
    Mar 2024 | consult to get established with a new reproductive immunologist (Alan Beer Center)
    Apr/May 2024 | required testing & waiting for a protocol
    May 2024 | protocol given / decided to go back to my old reproductive immunologist, Dr. Jubiz
    Jun / Jul 2024 | more testing, incl. SIS, ultrasound, and endometrial biopsy
    Jul 2024 | Dx chronic endometritis; 14 days of 100mg of doxy given
    Sep 2024 | Repeat endometrial biopsy; still + for chronic endometritis. 2 more antibiotics + an antiviral
    Oct 2024... currently awaiting a hysteroscopy (10/28) to check uterine cavity + check for endometritis


    TTC #1
    Me: 36, MH: 34 | Met 02/2009 | Started Dating 08/2017 | Married 02/02/2020
    TTC #1 02/2020 - 07/2022
    2009 | Dx PCOS; likely a misdiagnosis
    07/14/20 | Dx Hashimoto's Thyroditis
    07/21/20 | 1st RE appointment
    07/2120 - 08/20/20 | so much testing; no signs of PCOS
    08/20/20 | Dx Unexplained; AMA
    09/08/20 | IUI #1 Clomid + Trigger + Prometrium | BFN
    09/30/20 | Urology consult; more testing required
    10/2020 | Clomid + OPK + TI + Prometrium | BFN
    10/26/2020 | Starting 2nd IUI cycle, with Letrazole and with a new RE / different clinic
    11/03/2020 | New Dx "poor egg quality"; IUI cancelled in favor of Trigger + TI + Prometrium | BFN
    11/26/2020 | Combo IUI (Clomid + Menopur) + Trigger + Prometrium | BFN
    12/20/2020 | Combo IUI (Clomid + Gonal-F) + Trigger | IUI Cancelled due to thin lining; TI only | BFN
    01/14/2021 | Combo IUI (Letrazole + Menopur) + Trigger | BFN
    02/06/2021 | Switched to a new RE (TEW) ; trying naturally until we complete additional testing 
    03/14/2021 | Hybrid Double IUI, with Zymot (Letrazole, Gonal-F) + Trigger + Endometrin | Ovulated 4 mature eggs but still a BFN ☹️
    04/07/2021 | Natural cycle while we regroup | BFN
    04/09/2021 | Employer announces fertility benefits starting 05/01/2021! | Search for a new doctor who accepts insurance
    05/10/2021 | New RE consult & plan for IVF
    05/13/2021 | Mid-luteal IVF cycle #1 interrupted; had to get cancer genetic screening done to make sure I didn't have the same SDHA gene mutation as MH. 
    06/10/2021 | Aygestin priming IVF cycle #1; opted to Cx after 9 days of stims since only 5-6/12 follicles responded
    07/26/2021 | Attempt #2 at IVF cycle #1 (mid-luteal start): 8 retrieved, 8 MII, 6 fert (1 PN3), 3 Day 5 & 6 blasts: 3AA, 3AA, 6AB; 3 euploid
    08/09/2021 | Rest cycle / unmedicated TTC | Shockingly, a BFP! EDD: 5/25/202 | CP at 4w4d
    09/23/2021 | IVF cycle #2 (mid-luteal start): 14 retrieved, 13 MII, 11 fert, 5 Day 5 & 6 blasts: 2 x 3AA, 2 x 3AB, 3BB; 2 euploid
    11/12/2021 | IVF cycle #3 (mid-luteal start): cancelled due to ovaries being on vacation
    12/20/2021 | Rest cycle / unmedicated TTC + Pregmune Immunology Testing; BFN
    01/22/2022 | Rest cycle / unmedicated TTC + understanding uncovered immunological issues; BFN
    02/18/2022 | Mock transfer cycle! ERA, ReceptivaDx, EMMA/ALICE; start Prednisone to address NK activity
    03/16/2022 | Final, "Hail Mary" super-ovulation + TI cycle before FET; BFP! EDD: 12/21/2022 | MMC 05/08/2022
    05/20/2022 | D&C; recovering... 
    06/21/2022 | Trying naturally until October 2022
    07/21/2022 | BFP! EDD 04/02/2023; 👦🏼 born on 4/5/2023


  • abjm0325abjm0325 member
    edited February 2022
    @acleverusername Great information, thank you!
  • Okay quick question, I'm actually not totally sure this goes here, but probably? So I had a positive OPK on Monday evening (which is usually when I test, around 4:30pm or so), then Tuesday I had a positive in the early afternoon and then by 4:30pm it looked lighter, and today was obviously negative. So what does that indicate? I know usually when you get a positive, the day after that is O. (Or the day after whenever your last positive was). I won't be able to confirm it with my temps this cycle cause of the issue I had this morning (see today's WTO thread). So I'm curious if that info with the OPKs would help determine it for me. I'm wondering it was a Monday night/Tuesday morning O or something like that? Cause if that's the case, maybe this cycle wasn't a complete miss. But anyway. Attaching my chart for reference.


  • @annanbby the way i understand the rules of reading OPKs, what counts is the first positive OPK you receive. it doesn't matter how long the surge lasts thereafter. so although some people "test out" their LH surge each month it really isn't necessary. you can stop testing after the first positive. you can then expect to ovulate somewhere between 18-48 or sometimes even as long as 72 hrs after that first positive OPK. I feel like most charts I see around here tend to show a spike in BBT 1 or sometimes 2 days after the +OPK. I'm betting you'll get a temp bump tomorrow, but even if you don't, it's worth noting that it can sometimes take a day or two to build up the progesterone concentrations you need after ovulation to be reflected in your BBT. Sooooo, I did lurk your situ w/ grumpy SO in WTO, and all I can say is your timing on CD11 is well within the window if you ovulated on CD13.
    History
    I am doing this on my own. Left ovary and fallopian tube removed due to cyst/necrosis just after birth. Right ovary and tube still purport to function.
    Began TTC in Aug '18 @ age 35
    5 or 6 (or 7?!) cycles using frozen donor sperm, ICI. All BFN
    Mar-Jun '19 IUIs, all BFN
    Began process of referral for RE in spring of '19, blood tests confirm low AMH (.54) but all else is good.
    May '19 HSG shows open tube, but ultrasound suggests fibroids
    MRI in June '19 confirms two large fibroids, one growing through wall of uterus
    In June '19 I move from California to Oregon, disrupting my insurance, referrals, etc. 5 months spent piecing it all back together.
    Nov. '19 attempted myomectomy (vaginal approach) failed. 2nd surgery using laparoscopic method in Jan '20 is successful.
    April '20 --> June '20, natural IUIs, all BFN.
    July? saline ultrasound and bubble test demonstrate open tube
    July '20 clomid cycle cancelled for thin lining
    Aug-Oct, 3 femara cycles, all BFN
    RE referral. While waiting to set up an appointment Nov-Jan,I continue with natural cycles and ICI, using a known donor, BFN...
    Jan '21 more bloodwork, AMH is worse (.30), FSH high albeit not catastrophic at 13.2. hysteroscopy all good. "looks cozy!" says the RE.
    Feb '21, injectables (menopur, novarel), iui, BFN (doc said the frozen donor sperm sample had the "best numbers she'd ever seen!")
    Mar '21, injectables, iui cancelled due to lack of follicles, converted to at home-insem. BFN
    May '21, first IVF round cancelled due to cyst.
    July '21 IVF: standard antagonist. 225menupur/225gonal-f/cetrotide/5000u trigger, AFC 7; 6 days of stims. 8 eggs retrieved, 7 mature, 5 fertilize, 4 made it to blast. 3 are 4AB, 1 is 4BB. PGT-A results all abnormal.
    Oct '21 somewhat improved AMH (.51) and significantly improved FSH (8.9). Maybe it's all the pills I swallow.
    Dec -21, standard antagonist. 225menupur/225gonal-f/cetrotide/5000u trigger, AFC 5; 11 days of stims. retrieval yields 5, 4M, 2 reach day-6 blast (4AB & 4BB). 1 low-level mosaic (chr. 3 deletion), 1 complex abnormal.
    Feb '22 FET (low-level mosaic): CP.
    May '22 egg retrieval, lupron flare protocol. HGH priming for 1 month before stims; md lupron 20/20u daily; menopur 225, follistim 225, 10k trigger after 8 days of stims; AFC 10; 13 retrieved; 10 mature; 8 fertilized. All frozen at 2PN for later thaw, grow, and biopsy.
    July '22 egg retrieval same protocol: 9 days of stims; AFC 8; 10 retrieved, 8 mature, 4 fertilized and frozen.
    Sept '22 ER same protocol: AFC 10; 12 retrieved, 11 mature, 11 fertilized.
    From the 3 retrievals, 7 survived to day 5-6 blastocyst, from which I have 2 normal embryos!
    Jan 20, Fully medicated FET, baby aspirin, dexamethasone, acupuncture, and as much woo as I can stand (which isn't very much). BFN.
    July 23, Natural FET + baby aspirin. BFN.
  • @optimistgardener oh wow, that’s really helpful, I didn’t know that about the first positive OPK so that’ll be good to know for the future. And also encouraging that we may have made it within that window.
    Thank you for the info!! Six months in and I’m still learning. lol
  • @annanbby the way i understand the rules of reading OPKs, what counts is the first positive OPK you receive. it doesn't matter how long the surge lasts thereafter. so although some people "test out" their LH surge each month it really isn't necessary. you can stop testing after the first positive. you can then expect to ovulate somewhere between 18-48 or sometimes even as long as 72 hrs after that first positive OPK. I feel like most charts I see around here tend to show a spike in BBT 1 or sometimes 2 days after the +OPK. I'm betting you'll get a temp bump tomorrow, but even if you don't, it's worth noting that it can sometimes take a day or two to build up the progesterone concentrations you need after ovulation to be reflected in your BBT. Sooooo, I did lurk your situ w/ grumpy SO in WTO, and all I can say is your timing on CD11 is well within the window if you ovulated on CD13.
    Wow thanks for this nugget! I definitely did not know this either!
    Daisypath Anniversary tickers
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