Trying to Get Pregnant

IF Testing/Treatment w/o 11/30

This is a place for those of us who have already started TTC, but have started infertility testing and/or treatments. You can express your thoughts, feelings, and frustrations on infertility. TTC can be a long journey naturally, then add in the difficulties associated with infertility, and it becomes a whole new ball game. The road to infertility can be lonely, frustrating, and complicated, so let's make this a place where we can vent, ask questions, and support one another. Feel free to resurrect this thread at any point in the week if you have something to say. Treat this as an ongoing conversation. 

Diagnosis (if you've been): 

Status (WTO/TWW/TTA):

What are you doing this cycle? (Testing? Treatment?): 

How are things going?: 

Any questions?:

GTKY: Now that Thanksgiving is behind us, what is your favourite Christmas scent (what reminds you of Christmas when you smell it) and why? 

TTC History:

Me: 36  MH: 39, TTC since Dec 2017

Aug '18: PCOS dx

Nov '18: MH SA - 19mil

Dec '18-Mar '19: Letrozole + TI - all BFN

Apr '19: Letrozole + TI, - BFN.  Repeat SA (27mil) & DNA fragmentation test (17%)

Aug '19: Letrozole + HCG trigger + IUI + prog supp - BFN (MH: 16mil)

Sep '19: 2nd IUI, same protocol - BFN (MH: 16mil) 

Dec '19: IVF #1 w/ICSI, PGT. 5 retrieved, 4 fertilized, 3 blasts, 3 PGT-A normal.

Mar '20: FET #1, perfect 5AA blast transferred. BFN.

Sept '20: FET #2, 5BB tsf. 9/18/20 BFP!! EDD: 5/27/21. MMC 11w                                                  

Feb ‘21: FET #3, last 6BB blast transferred. BFP, EDD 11/2/21. MC 5w3d. 

May '21: IVF #2 w/ICSI, PGT. 8R, 7M, 6F, 6 blasts - 3AB, 3AB, 3BB, 4BB, 5BB, 6BA. Fresh tsf 5/13/21 - BFN. 

June '21: PGT-A results = 3 abnormal, 1 low level mosaic. Referred to new REI, had consult with 2nd RE in between. 


Sept '21: RPL, immune testing normal

Oct '21: IVF #3 w/IMSI, PGT. 33R, 26M, 23F, 9 blasts (7 day 6, 2 day 7). PGT-A = 5 normal, 1 mosaic

Dec '21: Positive for endometritis, RX Flagyl & Keflex

Jan '22: FET #5 - Kitchen sink immune/RIF protocol incl. PRP, intralipids, prednisone, medrol, nivestym, fragmin - CP

Feb '22: FET #6 - Kitchen sink immune/RIF protocol w/higher doses of pred & fragmin - BFN

Mar '22: Mock cycle for ERA - cancelled, repeat endometrial biopsy instead. Still positive for endometritis. RX ciprofloxacin & amoxicillin. 

Apr '22: IVF #4 w/IMSI, PGT. 28R, 23M, 16F, 11 blasts. PGT-A = 6 normal. 

June '22: FET #7 - Microdose lupron downreg w/kitchen sink immune/RIF protocol - double embryo transfer. BFN.

July '22: FET #8 - Mini stim w/Puregon + trigger, kitchen sink immune/RIF protocol. BFN. 

Sep '22: Taking a break

Dec '22: Attempted abdominal myomectomy, fibroid too close to cervix and major blood vessels. Wasn't removed. 

Feb '23: FET #9 - Modified natural w/baby asp, HCG trigger, PIO, PRP, Medrol, HCG wash, embryo glue - BFP!! EDD 11/11/23


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Re: IF Testing/Treatment w/o 11/30

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  • @acleverusername if it's not too late, to answer your Q last week about "priming the pump", if you don't have MFI or any specific instructions to abstain for a certain period of time, we would normally HIO 3-4 days before, then abstain for 1-2 days, and fool around the night before. Cont'd in spoiler for NSFW content :lol: 

    If this is your first time doing it I would recommend "practicing" earlier in your cycle just in case he's not able to stop lol (I know someone whose BF looked it up on his own and thought he'd give it a try the night before their SA but he took it too far, was too embarrassed to tell her what he'd done, then failed his SA spectacularly. When his repeat SA came back great he had to come clean about what he'd done. She was so mad at him at the time but it's kind of amusing after the fact :lol: ).
    The whole point is to get him juuuuust to the point before he ejaculates then stop. I think the technical term is semen retention. There haven't been many studies on it - most of them focus on length of abstinence period - but anecdotal stories indicate that it can be beneficial for sperm count and motility. 

    TTC History:

    Me: 36  MH: 39, TTC since Dec 2017

    Aug '18: PCOS dx

    Nov '18: MH SA - 19mil

    Dec '18-Mar '19: Letrozole + TI - all BFN

    Apr '19: Letrozole + TI, - BFN.  Repeat SA (27mil) & DNA fragmentation test (17%)

    Aug '19: Letrozole + HCG trigger + IUI + prog supp - BFN (MH: 16mil)

    Sep '19: 2nd IUI, same protocol - BFN (MH: 16mil) 

    Dec '19: IVF #1 w/ICSI, PGT. 5 retrieved, 4 fertilized, 3 blasts, 3 PGT-A normal.

    Mar '20: FET #1, perfect 5AA blast transferred. BFN.

    Sept '20: FET #2, 5BB tsf. 9/18/20 BFP!! EDD: 5/27/21. MMC 11w                                                  

    Feb ‘21: FET #3, last 6BB blast transferred. BFP, EDD 11/2/21. MC 5w3d. 

    May '21: IVF #2 w/ICSI, PGT. 8R, 7M, 6F, 6 blasts - 3AB, 3AB, 3BB, 4BB, 5BB, 6BA. Fresh tsf 5/13/21 - BFN. 

    June '21: PGT-A results = 3 abnormal, 1 low level mosaic. Referred to new REI, had consult with 2nd RE in between. 


    Sept '21: RPL, immune testing normal

    Oct '21: IVF #3 w/IMSI, PGT. 33R, 26M, 23F, 9 blasts (7 day 6, 2 day 7). PGT-A = 5 normal, 1 mosaic

    Dec '21: Positive for endometritis, RX Flagyl & Keflex

    Jan '22: FET #5 - Kitchen sink immune/RIF protocol incl. PRP, intralipids, prednisone, medrol, nivestym, fragmin - CP

    Feb '22: FET #6 - Kitchen sink immune/RIF protocol w/higher doses of pred & fragmin - BFN

    Mar '22: Mock cycle for ERA - cancelled, repeat endometrial biopsy instead. Still positive for endometritis. RX ciprofloxacin & amoxicillin. 

    Apr '22: IVF #4 w/IMSI, PGT. 28R, 23M, 16F, 11 blasts. PGT-A = 6 normal. 

    June '22: FET #7 - Microdose lupron downreg w/kitchen sink immune/RIF protocol - double embryo transfer. BFN.

    July '22: FET #8 - Mini stim w/Puregon + trigger, kitchen sink immune/RIF protocol. BFN. 

    Sep '22: Taking a break

    Dec '22: Attempted abdominal myomectomy, fibroid too close to cervix and major blood vessels. Wasn't removed. 

    Feb '23: FET #9 - Modified natural w/baby asp, HCG trigger, PIO, PRP, Medrol, HCG wash, embryo glue - BFP!! EDD 11/11/23


  • @kiki047 have you tried acupuncture before? I have been thinking about trying it, but having a hard time reaching the local person via message/email (Im too nervous to call yet). 🤣 I haven’t personally used an osteopath, but I’ve heard really good things about it! I like gingers idea of asking for a tele-med appointment if possible.
    @gingermama29 I really hope you see a positive OPK soon! I would wait 2-3 days after your last TI before doing an SA. But I also wouldn’t take my advice heavily, as I’m new to all of this.

    Diagnosis (if you've been): testing

    Status (WTO/TWW/TTA): WTO

    What are you doing this cycle? (Testing? Treatment?): I go in for bloodwork at 12:30 today. I’m thinking I might request CD21 (7dpo, right) bloodwork for this cycle too, as I feel like that might reveal more.

    How are things going?: I’m surprisingly okay with the arrival of AF over the weekend. I really thought I’d fall apart, but I didn’t.

    Any questions?: Too many yet. I’m slowly learning from all you amazing women.

    GTKY: Now that Thanksgiving is behind us, what is your favourite Christmas scent (what reminds you of Christmas when you smell it) and why? Gingerbread or Christmas tree. We do fake trees, but I miss the smell of a fresh pine tree. I also just really love the smell of cookies and gingerbread is my favorite to smell, even though I don’t enjoy eating them. 
    TTC History

    Me: 26 DH: 27

    TTC #1 | June '18-August '18 | DD | Born April 21, 2019 | Due May 10, 2019

    Lilypie Third Birthday tickers

    TTC#2 | June '20-February '21 | DS | Due October 27, 2021

    Lilypie Maternity tickers

  • kiki047kiki047 member
    edited November 2020
    @gingermama29 I would agree that I'd wait until you're safely in your TWW to do the SA. You wouldn't get results back in time to have any meaningful answers before you O so you might as well wait until he can abstain for the recommended 2-5 days without interrupting your TI. As for the Osteopath, they're similar to a chiropractor with manual adjustments (but looking at the body as a whole in the way your various musculo-skeletal systems relate to each other) so it unfortunately isn't something that can be done virtually. 
    @chindimples04 I have been doing acupuncture for a couple years now but very off and on. For my last FET I was only able to see her the day of my transfer and wasn't allowed to go back because I was sick (pink eye, which is a covid symptom though I had 2 negative tests 2 weeks apart). They've since changed their protocols so that if you have one-off symptoms, they'll still let you come in if you can produce a negative result in the last week so I feel a little better about not having that interruption in my care this time around. 

    Edited to fix typo.

    TTC History:

    Me: 36  MH: 39, TTC since Dec 2017

    Aug '18: PCOS dx

    Nov '18: MH SA - 19mil

    Dec '18-Mar '19: Letrozole + TI - all BFN

    Apr '19: Letrozole + TI, - BFN.  Repeat SA (27mil) & DNA fragmentation test (17%)

    Aug '19: Letrozole + HCG trigger + IUI + prog supp - BFN (MH: 16mil)

    Sep '19: 2nd IUI, same protocol - BFN (MH: 16mil) 

    Dec '19: IVF #1 w/ICSI, PGT. 5 retrieved, 4 fertilized, 3 blasts, 3 PGT-A normal.

    Mar '20: FET #1, perfect 5AA blast transferred. BFN.

    Sept '20: FET #2, 5BB tsf. 9/18/20 BFP!! EDD: 5/27/21. MMC 11w                                                  

    Feb ‘21: FET #3, last 6BB blast transferred. BFP, EDD 11/2/21. MC 5w3d. 

    May '21: IVF #2 w/ICSI, PGT. 8R, 7M, 6F, 6 blasts - 3AB, 3AB, 3BB, 4BB, 5BB, 6BA. Fresh tsf 5/13/21 - BFN. 

    June '21: PGT-A results = 3 abnormal, 1 low level mosaic. Referred to new REI, had consult with 2nd RE in between. 


    Sept '21: RPL, immune testing normal

    Oct '21: IVF #3 w/IMSI, PGT. 33R, 26M, 23F, 9 blasts (7 day 6, 2 day 7). PGT-A = 5 normal, 1 mosaic

    Dec '21: Positive for endometritis, RX Flagyl & Keflex

    Jan '22: FET #5 - Kitchen sink immune/RIF protocol incl. PRP, intralipids, prednisone, medrol, nivestym, fragmin - CP

    Feb '22: FET #6 - Kitchen sink immune/RIF protocol w/higher doses of pred & fragmin - BFN

    Mar '22: Mock cycle for ERA - cancelled, repeat endometrial biopsy instead. Still positive for endometritis. RX ciprofloxacin & amoxicillin. 

    Apr '22: IVF #4 w/IMSI, PGT. 28R, 23M, 16F, 11 blasts. PGT-A = 6 normal. 

    June '22: FET #7 - Microdose lupron downreg w/kitchen sink immune/RIF protocol - double embryo transfer. BFN.

    July '22: FET #8 - Mini stim w/Puregon + trigger, kitchen sink immune/RIF protocol. BFN. 

    Sep '22: Taking a break

    Dec '22: Attempted abdominal myomectomy, fibroid too close to cervix and major blood vessels. Wasn't removed. 

    Feb '23: FET #9 - Modified natural w/baby asp, HCG trigger, PIO, PRP, Medrol, HCG wash, embryo glue - BFP!! EDD 11/11/23


  • @kiki047 GL with the new protocol! I don’t really know anything about osteopaths, so I don’t have any advice for you. But if you do decide to move forward with that, I hope you find it helpful!

    @gingermama29 Ugh so frustrating about no Saturday appointments for YH! If I were you, I would wait until after O to do the SA. I wouldn’t want to “waste” anything!!

    @chindimples04 GL with your bw...hopefully it comes back quickly and is informative!

    Diagnosis (if you've been): unexplained 

    Status (WTO/TWW/TTA): TWW

    What are you doing this cycle? (Testing? Treatment?): IUI #2 was just over a week ago

    How are things going?: pretty good! As anticipated, the first week of the TWW went so quickly and I was really able to keep myself distracted. Now I just have to make it until Thursday or Friday to test! We got all of our Christmas decorations up (minus the tree) and it all just makes me so happy to look at. DH and I have a pizza night planned for Saturday and here is how we phrased it: “we will either be happy with pizza, or sad with pizza and wine and Christmas”. LOL hoping for the former, not the latter 😂

    Any questions?:

    GTKY: Now that Thanksgiving is behind us, what is your favourite Christmas scent (what reminds you of Christmas when you smell it) and why? Fresh cut Christmas tree! We always had a real one growing up, and I got DH sold on a real one when we got married. That and I totally agree with apple/cinnamon...I have my apple cinnamon candle on right at this moment!
  • @runningoncookies ohh good luck with the last stretch of the TWW. Hope your pizza night is happy and cheerful, for all the good reasons!! <3 

    New question - has anyone heard of low-dose naltrexone for use in IF treatment? From what I know it's still pretty experimental, and the way it was described to me was that it's so effective that drug companies don't want to make it because it'll make their other fertility treatments obsolete. Of course I rolled my eyes at that part but the limited research I've done is pretty interesting, and even CNY has it listed on their website as one of their alternative treatment options. 

    Paging the grads who might have heard of it too? @emmasemm

    TTC History:

    Me: 36  MH: 39, TTC since Dec 2017

    Aug '18: PCOS dx

    Nov '18: MH SA - 19mil

    Dec '18-Mar '19: Letrozole + TI - all BFN

    Apr '19: Letrozole + TI, - BFN.  Repeat SA (27mil) & DNA fragmentation test (17%)

    Aug '19: Letrozole + HCG trigger + IUI + prog supp - BFN (MH: 16mil)

    Sep '19: 2nd IUI, same protocol - BFN (MH: 16mil) 

    Dec '19: IVF #1 w/ICSI, PGT. 5 retrieved, 4 fertilized, 3 blasts, 3 PGT-A normal.

    Mar '20: FET #1, perfect 5AA blast transferred. BFN.

    Sept '20: FET #2, 5BB tsf. 9/18/20 BFP!! EDD: 5/27/21. MMC 11w                                                  

    Feb ‘21: FET #3, last 6BB blast transferred. BFP, EDD 11/2/21. MC 5w3d. 

    May '21: IVF #2 w/ICSI, PGT. 8R, 7M, 6F, 6 blasts - 3AB, 3AB, 3BB, 4BB, 5BB, 6BA. Fresh tsf 5/13/21 - BFN. 

    June '21: PGT-A results = 3 abnormal, 1 low level mosaic. Referred to new REI, had consult with 2nd RE in between. 


    Sept '21: RPL, immune testing normal

    Oct '21: IVF #3 w/IMSI, PGT. 33R, 26M, 23F, 9 blasts (7 day 6, 2 day 7). PGT-A = 5 normal, 1 mosaic

    Dec '21: Positive for endometritis, RX Flagyl & Keflex

    Jan '22: FET #5 - Kitchen sink immune/RIF protocol incl. PRP, intralipids, prednisone, medrol, nivestym, fragmin - CP

    Feb '22: FET #6 - Kitchen sink immune/RIF protocol w/higher doses of pred & fragmin - BFN

    Mar '22: Mock cycle for ERA - cancelled, repeat endometrial biopsy instead. Still positive for endometritis. RX ciprofloxacin & amoxicillin. 

    Apr '22: IVF #4 w/IMSI, PGT. 28R, 23M, 16F, 11 blasts. PGT-A = 6 normal. 

    June '22: FET #7 - Microdose lupron downreg w/kitchen sink immune/RIF protocol - double embryo transfer. BFN.

    July '22: FET #8 - Mini stim w/Puregon + trigger, kitchen sink immune/RIF protocol. BFN. 

    Sep '22: Taking a break

    Dec '22: Attempted abdominal myomectomy, fibroid too close to cervix and major blood vessels. Wasn't removed. 

    Feb '23: FET #9 - Modified natural w/baby asp, HCG trigger, PIO, PRP, Medrol, HCG wash, embryo glue - BFP!! EDD 11/11/23


  • @runningoncookies I hope you are happy with pizza! ❤️ 🍕 

    Some of my bloodwork has come back already. TSH was 1.29 uU/mL and progesterone was .3 ng/mL. They haven’t left any notes on those yet but according to Dr. Google, and the standard range they gave me, they both seem to be normal, which is good but also frustrating. I’m still waiting for FSH and maybe estradiol (I can’t remember if they ordered this or not). So, feeling stuck, basically.
    TTC History

    Me: 26 DH: 27

    TTC #1 | June '18-August '18 | DD | Born April 21, 2019 | Due May 10, 2019

    Lilypie Third Birthday tickers

    TTC#2 | June '20-February '21 | DS | Due October 27, 2021

    Lilypie Maternity tickers

  • TW mention of success

    @kik0407 Yes I have definitely researched it - and if we had been unsuccessful with our FET then we would have been trying that the next time. Particularly because I have an underlying autoimmune condition and the main off label low dose usage is for autoimmune diseases. However neither by RE nor my rheumatologist were willing to use it in combination with steroids and there were more small studies and anecdotal evidence on low dose steroid use during FET than for LDN so we went with steroids as first option.
    At the moment quite a few Drs are less willing to prescribe either steroids or LDN as both basically reduce the effectiveness of the immune system which could lead to a patient becoming more seriously ill with Covid if they caught it and could mean that neither would be a treatment option if they did catch COVID. Some countries have even placed limits on which Drs can prescribe those at the moment ( eg UK).
    There is a risk with LDN that autoimmune symptoms can flare - but still the majority seem to have improvement in symptoms.
    I was also warned we would need to stop the LDN already around 6 weeks as my RE was nervous about potential effect on the fetus in that important neural development stage from 6-12 weeks whereas there is no research to show any risk from low dose prednisolone use during that period (and its use is a lot more prevalent) and I actually stayed on it right until after birth (and am back on it again).
    And both steroids and LDN are only “recommended” for transfer, not for retrieval. So overall best used in an FET cycle.
    As a side note, we did combine Intralipids with the prednisolone - and whilst I have taken (and am taking currently) the prednisolone with only minor improvements felt, don’t know if it was the pregnancy hormones or the intralipids but I felt like superwoman the whole of 1st tri when I was having intralipids every 2 weeks... 

    Hope this gives you some things to think about and talk about with your RE.

    Any more questions just let me know!

    Me 43 DH 45
    Married 12/2016
    TTC #1 since 04/2015
    AMA, DOR (AMH 0.65, AFC 2-4) and autoimmune issues (RA, APS), low TSH, adenomyosis
    7 retrievals, 3 transfers
    Jun19 FET BFP, due date 7th March 2020, DD born Feb20
    Sep17 IVF1 - 1ER, 1F, 1ET, BFN
    Nov17 IVF2 - 1ER, 0F
    Jan18 IVF3 - 3ER, 1F, 1ET, BFN
    Feb18 - second opinion and additional testing
    Apr18 IVF4 - cancelled (E2 too high)
    May/Jun18 IVF4 - 4ER, 0M, 1F, 1 frozen day 3 (not best quality)
    Jun/Jul18 IVF5 - 5 ER, 3M, 2F, 2 frozen day 3 (not best quality)
    Jul/Aug18 IVF6 - 4ER, 3M, 2F, 2 frozen day 3 (good quality)
    Aug/Sep18 IVF7 - cancelled (cyst)
    Sep/Oct18 IVF7 - 3ER, 3M, 2F, 2 frozen Day 3 (excellent quality)
    Oct18 IVF8 - Cancelled (cyst and too low TSH)
    Oct18-Jan19 bringing TSH under control
    Feb19 ERA and hysteroscopy
    Mar19 Investigation for fibroid and adenomyosis
    Apr19 adenomyosis confirmed, polyps removed
    Jun19 FET after 2 months Lupron, autoimmune protocol, transferred two day 3 frozen embryos
    Sep17 - Pergoveris 10-17 Sep, Orgalutran 15-18 Sep, Ovitrelle 18 Sep, ER 20 Sep for 2 follies, 1 mature egg, fertilized, ET 1x 2d 4-cell embryo 22/09, 05/10 BFN
    Nov17 IVF2 - Pergoveris 2-14 Nov, Orgalutran 5-14 Nov, Ovitrelle 15 Nov, ER 17 Nov for 3 follies, 1 mature egg, did not fertilize
    Jan18 IVF3 - Pergoveris 30 Dec - 8 Jan, Orgalutran 5-8 Jan, Ovitrelle 9 Jan, ER 11 Jan 3 eggs, 2 mature, 1 fertilized, ET 1x 4d 12-cell embryo 15/01, 24/01 BFN
    May/Jun18 IVF4 - Rekovelle 25-29 May, Menogon 30May - 2Jun, Zomacton 25 27 29 31 May and 2Jun, Cetrotide 30May - 3Jun, Gonasi 3Jun, ER 5Jun 4 eggs, none mature, two matured overnight, 1 fertilized with ICSI, Frozen day 3 but not good quality
    Jun/Jul18 IVF5 - Rekovelle 21-24 June, Menogon 25Jun-3Jul, Puregon 4-5Jul, Zomacton 21 23 25 27 29 Jun, Cetrotide 25Jun-5Jul, Gonasi 6Jul, ER 8Jul 5 eggs, 3 mature, 2 fertilized with ICSI, 2 frozen day 3 but not good quality
    Jul/Aug18 IVF6 - Rekovelle 26-29 Jul, Menogon 30Jul-7Aug, Buserelin 26Jul-7Aug, Zomacton 26 28 30 Jul 1 3 Aug, Gonasi 7Aug, ER 9Aug 4 eggs, 3 mature, 2 fertilized (normal IVF), 2 frozen day 3 good quality
    Sep/Oct18 IVF7 - Menogon 19-30Sep, Buserelin 19-30Sep, Zomacton 19 21 23 25 27 Sep, Ovitrelle 1 Oct, ER 3 eggs, 3 mature, 2 fertilized with ICSI, 2 frozen day 3 excellent quality 

    Fav Quote: The greatest thing you'll ever learn is just to love and be loved in return

  • Well, we had the first injection on Sunday and my second one yesterday.  I have been feeling bloated in the morning and am guessing that will be fairly common in the near future.  It’s kind of sore and uncomfortable.  We will see where it goes.
  • @emmasemm to the rescue, as always. Thank you for the info. That's really enlightening. I didn't even think about the impact of Covid in all of this, that's a good point, though only compounds the frustration I'm sure we're all feeling when this looming outside force is so restrictive on our treatment options/timing. This isn't something I'd be looking at for my upcoming FET but it sounds intriguing, something I'll be asking my RE about down the @misshelen86 I have everything crossed for your FET this month!! I can completely understand how stressful Christmas will be with your sister AND SIL both being pregnant, and I hope you can find ways to cope and get through it however you need to. 
    @laura-kay congrats on starting your injections. The bloat is unfortunately pretty normal, hope you have lots of stretchy pants! 

    TTC History:

    Me: 36  MH: 39, TTC since Dec 2017

    Aug '18: PCOS dx

    Nov '18: MH SA - 19mil

    Dec '18-Mar '19: Letrozole + TI - all BFN

    Apr '19: Letrozole + TI, - BFN.  Repeat SA (27mil) & DNA fragmentation test (17%)

    Aug '19: Letrozole + HCG trigger + IUI + prog supp - BFN (MH: 16mil)

    Sep '19: 2nd IUI, same protocol - BFN (MH: 16mil) 

    Dec '19: IVF #1 w/ICSI, PGT. 5 retrieved, 4 fertilized, 3 blasts, 3 PGT-A normal.

    Mar '20: FET #1, perfect 5AA blast transferred. BFN.

    Sept '20: FET #2, 5BB tsf. 9/18/20 BFP!! EDD: 5/27/21. MMC 11w                                                  

    Feb ‘21: FET #3, last 6BB blast transferred. BFP, EDD 11/2/21. MC 5w3d. 

    May '21: IVF #2 w/ICSI, PGT. 8R, 7M, 6F, 6 blasts - 3AB, 3AB, 3BB, 4BB, 5BB, 6BA. Fresh tsf 5/13/21 - BFN. 

    June '21: PGT-A results = 3 abnormal, 1 low level mosaic. Referred to new REI, had consult with 2nd RE in between. 


    Sept '21: RPL, immune testing normal

    Oct '21: IVF #3 w/IMSI, PGT. 33R, 26M, 23F, 9 blasts (7 day 6, 2 day 7). PGT-A = 5 normal, 1 mosaic

    Dec '21: Positive for endometritis, RX Flagyl & Keflex

    Jan '22: FET #5 - Kitchen sink immune/RIF protocol incl. PRP, intralipids, prednisone, medrol, nivestym, fragmin - CP

    Feb '22: FET #6 - Kitchen sink immune/RIF protocol w/higher doses of pred & fragmin - BFN

    Mar '22: Mock cycle for ERA - cancelled, repeat endometrial biopsy instead. Still positive for endometritis. RX ciprofloxacin & amoxicillin. 

    Apr '22: IVF #4 w/IMSI, PGT. 28R, 23M, 16F, 11 blasts. PGT-A = 6 normal. 

    June '22: FET #7 - Microdose lupron downreg w/kitchen sink immune/RIF protocol - double embryo transfer. BFN.

    July '22: FET #8 - Mini stim w/Puregon + trigger, kitchen sink immune/RIF protocol. BFN. 

    Sep '22: Taking a break

    Dec '22: Attempted abdominal myomectomy, fibroid too close to cervix and major blood vessels. Wasn't removed. 

    Feb '23: FET #9 - Modified natural w/baby asp, HCG trigger, PIO, PRP, Medrol, HCG wash, embryo glue - BFP!! EDD 11/11/23


  • @krash_ I feel like I associate osteopaths with old people, and I don't know where that association came from because I don't think that's generally the case :lol:  I'm going to look into it some more though. Creeping on your response to @misshelen86, it seems to be a fairly universal standard (at least in Canada, anyway) that the embryology labs close over the Christmas break for their annual deep clean, so they don't schedule procedures around that time to ensure they won't interfere with timing/active cycles.
    Re: suppositories - YUP, oh can I ever relate. It's so gross. I'd actually take the PIO injections over suppositories any day, I just hate that leaking feeling. 
    Re: your beta test, my clinic makes me come in for my beta even if AF arrives, I guess to see if there's any tiny amount of HCG (indicating a CP). Tbh I didn't go after any of my IUIs because AF arrived right on schedule, and they gave me heck for it after.

    TTC History:

    Me: 36  MH: 39, TTC since Dec 2017

    Aug '18: PCOS dx

    Nov '18: MH SA - 19mil

    Dec '18-Mar '19: Letrozole + TI - all BFN

    Apr '19: Letrozole + TI, - BFN.  Repeat SA (27mil) & DNA fragmentation test (17%)

    Aug '19: Letrozole + HCG trigger + IUI + prog supp - BFN (MH: 16mil)

    Sep '19: 2nd IUI, same protocol - BFN (MH: 16mil) 

    Dec '19: IVF #1 w/ICSI, PGT. 5 retrieved, 4 fertilized, 3 blasts, 3 PGT-A normal.

    Mar '20: FET #1, perfect 5AA blast transferred. BFN.

    Sept '20: FET #2, 5BB tsf. 9/18/20 BFP!! EDD: 5/27/21. MMC 11w                                                  

    Feb ‘21: FET #3, last 6BB blast transferred. BFP, EDD 11/2/21. MC 5w3d. 

    May '21: IVF #2 w/ICSI, PGT. 8R, 7M, 6F, 6 blasts - 3AB, 3AB, 3BB, 4BB, 5BB, 6BA. Fresh tsf 5/13/21 - BFN. 

    June '21: PGT-A results = 3 abnormal, 1 low level mosaic. Referred to new REI, had consult with 2nd RE in between. 


    Sept '21: RPL, immune testing normal

    Oct '21: IVF #3 w/IMSI, PGT. 33R, 26M, 23F, 9 blasts (7 day 6, 2 day 7). PGT-A = 5 normal, 1 mosaic

    Dec '21: Positive for endometritis, RX Flagyl & Keflex

    Jan '22: FET #5 - Kitchen sink immune/RIF protocol incl. PRP, intralipids, prednisone, medrol, nivestym, fragmin - CP

    Feb '22: FET #6 - Kitchen sink immune/RIF protocol w/higher doses of pred & fragmin - BFN

    Mar '22: Mock cycle for ERA - cancelled, repeat endometrial biopsy instead. Still positive for endometritis. RX ciprofloxacin & amoxicillin. 

    Apr '22: IVF #4 w/IMSI, PGT. 28R, 23M, 16F, 11 blasts. PGT-A = 6 normal. 

    June '22: FET #7 - Microdose lupron downreg w/kitchen sink immune/RIF protocol - double embryo transfer. BFN.

    July '22: FET #8 - Mini stim w/Puregon + trigger, kitchen sink immune/RIF protocol. BFN. 

    Sep '22: Taking a break

    Dec '22: Attempted abdominal myomectomy, fibroid too close to cervix and major blood vessels. Wasn't removed. 

    Feb '23: FET #9 - Modified natural w/baby asp, HCG trigger, PIO, PRP, Medrol, HCG wash, embryo glue - BFP!! EDD 11/11/23


  • @kiki047 I see an osteopath, and whilst she's not focused on fertility, she definitely has other fertility patients and is keenly aware of that we're currently trying. She's mentioned a couple of times that my left ovary was "stuck" and has done a lot of manipulations in my pelvic region. I'm still not KU'ed but I'm basically willing to try. Obviously research into benefits of osteopathy on fertility is very limited, but I did find this one paper that talked about it. N is 10 so, yeah, not exactly a gold standard when it comes to research. 

    Will be back later for more tags and updates!

    TTC History
    TTC#2
    Me: 41; MH: 40 | Met 02/2009 | Started Dating 08/2017 | Married 02/02/2020
    Mar 2024 | consult to get established with a new reproductive immunologist (Alan Beer Center)
    Apr/May 2024 | required testing & waiting for a protocol
    May 2024 | protocol given / decided to go back to my old reproductive immunologist, Dr. Jubiz
    Jun / Jul 2024 | more testing, incl. SIS, ultrasound, and endometrial biopsy
    Jul 2024 | Dx chronic endometritis; 14 days of 100mg of doxy given
    Sep 2024 | Repeat endometrial biopsy; still + for chronic endometritis. 2 more antibiotics + an antiviral
    Oct 2024 | Hysteroscopy turned polypectomy; endometriosis consult w/ specialist who confirmed high likelihood of endo based on symptoms and ultrasound; lots of blood tests ordered
    Mar 2025 | Endo excision surgery. Stage 3 endo found! Recoveing
    Apr 2025 | Planning transfer w/ RE & green light protocol w/ RI; target transfer July or August 2025
    May 2025 | Surprise BFP! EDD 1/11/2026


    TTC #1
    Me: 36, MH: 34 | Met 02/2009 | Started Dating 08/2017 | Married 02/02/2020
    TTC #1 02/2020 - 07/2022
    2009 | Dx PCOS; likely a misdiagnosis
    07/14/20 | Dx Hashimoto's Thyroditis
    07/21/20 | 1st RE appointment
    07/2120 - 08/20/20 | so much testing; no signs of PCOS
    08/20/20 | Dx Unexplained; AMA
    09/08/20 | IUI #1 Clomid + Trigger + Prometrium | BFN
    09/30/20 | Urology consult; more testing required
    10/2020 | Clomid + OPK + TI + Prometrium | BFN
    10/26/2020 | Starting 2nd IUI cycle, with Letrazole and with a new RE / different clinic
    11/03/2020 | New Dx "poor egg quality"; IUI cancelled in favor of Trigger + TI + Prometrium | BFN
    11/26/2020 | Combo IUI (Clomid + Menopur) + Trigger + Prometrium | BFN
    12/20/2020 | Combo IUI (Clomid + Gonal-F) + Trigger | IUI Cancelled due to thin lining; TI only | BFN
    01/14/2021 | Combo IUI (Letrazole + Menopur) + Trigger | BFN
    02/06/2021 | Switched to a new RE (TEW) ; trying naturally until we complete additional testing 
    03/14/2021 | Hybrid Double IUI, with Zymot (Letrazole, Gonal-F) + Trigger + Endometrin | Ovulated 4 mature eggs but still a BFN ☹️
    04/07/2021 | Natural cycle while we regroup | BFN
    04/09/2021 | Employer announces fertility benefits starting 05/01/2021! | Search for a new doctor who accepts insurance
    05/10/2021 | New RE consult & plan for IVF
    05/13/2021 | Mid-luteal IVF cycle #1 interrupted; had to get cancer genetic screening done to make sure I didn't have the same SDHA gene mutation as MH. 
    06/10/2021 | Aygestin priming IVF cycle #1; opted to Cx after 9 days of stims since only 5-6/12 follicles responded
    07/26/2021 | Attempt #2 at IVF cycle #1 (mid-luteal start): 8 retrieved, 8 MII, 6 fert (1 PN3), 3 Day 5 & 6 blasts: 3AA, 3AA, 6AB; 3 euploid
    08/09/2021 | Rest cycle / unmedicated TTC | Shockingly, a BFP! EDD: 5/25/202 | CP at 4w4d
    09/23/2021 | IVF cycle #2 (mid-luteal start): 14 retrieved, 13 MII, 11 fert, 5 Day 5 & 6 blasts: 2 x 3AA, 2 x 3AB, 3BB; 2 euploid
    11/12/2021 | IVF cycle #3 (mid-luteal start): cancelled due to ovaries being on vacation
    12/20/2021 | Rest cycle / unmedicated TTC + Pregmune Immunology Testing; BFN
    01/22/2022 | Rest cycle / unmedicated TTC + understanding uncovered immunological issues; BFN
    02/18/2022 | Mock transfer cycle! ERA, ReceptivaDx, EMMA/ALICE; start Prednisone to address NK activity
    03/16/2022 | Final, "Hail Mary" super-ovulation + TI cycle before FET; BFP! EDD: 12/21/2022 | MMC 05/08/2022
    05/20/2022 | D&C; recovering... 
    06/21/2022 | Trying naturally until October 2022
    07/21/2022 | BFP! EDD 04/02/2023; 👦🏼 born on 4/5/2023


  • @laura-kay gl with the injections this cycle! 
    @krash_ no personal experience with going in for betas but what I’ve seen from other people in a similar journey on TikTok, they don’t take an HPT until after betas, but if you O’d last Wednesday, that would make not taking a HPT really hard! I wouldn’t go in for betas if AF showed up, though. As for your question, no, they didn’t order a prolactin lab. I asked for it and they said no. *tw lc*

    I’m guessing they said no since I still breastfeed once a day. 

    TTC History

    Me: 26 DH: 27

    TTC #1 | June '18-August '18 | DD | Born April 21, 2019 | Due May 10, 2019

    Lilypie Third Birthday tickers

    TTC#2 | June '20-February '21 | DS | Due October 27, 2021

    Lilypie Maternity tickers

  • Question: after mock transfer/ERA, did you have a horrible period?

    *TW for TMI
    It’s been so heavy with huge clots.. the pain this morning was about 7 or 8 out of 10 and I was throwing up. It’s eased up now with some Advil but I decided to call in to work in case it starts up again. My period was heavier & more painful than usual after my retrieval, but nothing like this!
    Me: 35 DH: 35
    TTC since 9/2018
    Dx: MFI
    10/19- First RE visit
    2/20- DH had surgery for bilateral varicoceles 
    7/20- IUI with 5 mg letrozole- BFN
    9/20- IVF. 9 eggs retrieved, 9 mature, 8 fertilized with ICSI, 7 blasts, 4 PGT-A normal
    11/20- Mock transfer/ERA
    12/20- FET #1- transferred one 4AB- BFN
    3/21- FET #2- transferred one 3AB- BFP! Due Dec 2021
    12/21- Baby girl born!

  • @misshelen86 that also sounds like how my period was too the first cycle following my ER. In theory, yes if you were doing your full protocol for the mock/ERA then your lining would have (hopefully) been nice and thick which could result in a much heavier period than normal. I'm so sorry, it's such an awful feeling. Hopefully you have a heating pad and can get some rest until it eases up. :'( 

    TTC History:

    Me: 36  MH: 39, TTC since Dec 2017

    Aug '18: PCOS dx

    Nov '18: MH SA - 19mil

    Dec '18-Mar '19: Letrozole + TI - all BFN

    Apr '19: Letrozole + TI, - BFN.  Repeat SA (27mil) & DNA fragmentation test (17%)

    Aug '19: Letrozole + HCG trigger + IUI + prog supp - BFN (MH: 16mil)

    Sep '19: 2nd IUI, same protocol - BFN (MH: 16mil) 

    Dec '19: IVF #1 w/ICSI, PGT. 5 retrieved, 4 fertilized, 3 blasts, 3 PGT-A normal.

    Mar '20: FET #1, perfect 5AA blast transferred. BFN.

    Sept '20: FET #2, 5BB tsf. 9/18/20 BFP!! EDD: 5/27/21. MMC 11w                                                  

    Feb ‘21: FET #3, last 6BB blast transferred. BFP, EDD 11/2/21. MC 5w3d. 

    May '21: IVF #2 w/ICSI, PGT. 8R, 7M, 6F, 6 blasts - 3AB, 3AB, 3BB, 4BB, 5BB, 6BA. Fresh tsf 5/13/21 - BFN. 

    June '21: PGT-A results = 3 abnormal, 1 low level mosaic. Referred to new REI, had consult with 2nd RE in between. 


    Sept '21: RPL, immune testing normal

    Oct '21: IVF #3 w/IMSI, PGT. 33R, 26M, 23F, 9 blasts (7 day 6, 2 day 7). PGT-A = 5 normal, 1 mosaic

    Dec '21: Positive for endometritis, RX Flagyl & Keflex

    Jan '22: FET #5 - Kitchen sink immune/RIF protocol incl. PRP, intralipids, prednisone, medrol, nivestym, fragmin - CP

    Feb '22: FET #6 - Kitchen sink immune/RIF protocol w/higher doses of pred & fragmin - BFN

    Mar '22: Mock cycle for ERA - cancelled, repeat endometrial biopsy instead. Still positive for endometritis. RX ciprofloxacin & amoxicillin. 

    Apr '22: IVF #4 w/IMSI, PGT. 28R, 23M, 16F, 11 blasts. PGT-A = 6 normal. 

    June '22: FET #7 - Microdose lupron downreg w/kitchen sink immune/RIF protocol - double embryo transfer. BFN.

    July '22: FET #8 - Mini stim w/Puregon + trigger, kitchen sink immune/RIF protocol. BFN. 

    Sep '22: Taking a break

    Dec '22: Attempted abdominal myomectomy, fibroid too close to cervix and major blood vessels. Wasn't removed. 

    Feb '23: FET #9 - Modified natural w/baby asp, HCG trigger, PIO, PRP, Medrol, HCG wash, embryo glue - BFP!! EDD 11/11/23


  • Well, FSH just came back very normal (6.2 IU/L, normal range is 3.5-12.5 for follicular phase). So, we are back to the drawing board. I’m not sure what they will allow me to get bloodwork for. It was a fight getting this, and with it coming back normal, I have a feeling they aren’t going to be as willing to do more. Only time shall tell.
    TTC History

    Me: 26 DH: 27

    TTC #1 | June '18-August '18 | DD | Born April 21, 2019 | Due May 10, 2019

    Lilypie Third Birthday tickers

    TTC#2 | June '20-February '21 | DS | Due October 27, 2021

    Lilypie Maternity tickers

  • @kiki047 Thanks so much friend. I was getting really worried because that amount of pain seemed excessive but it makes me feel a bit better to know you had a similar experience after ER. It’s weird though because this has been so much worse for me than my period after ER, even though my lining was much thicker with the ER. 

    @krash_ No, unfortunately this is the only fertility clinic in the city and a dr’s office isn’t equipped or trained to do a transfer. So I’m just keeping everything crossed my lining will be ready! I hear you on the progesterone suppositories!! They are awful!! I hate the mess and the constant leaking. If you HIO Tuesday night, you still are in your window.. remember sperm can live for up to 5 days in fertile CM. And yes, you should still do the beta.. I’ve heard of people thinking they had AF but it was actually implantation bleeding. 

    @chindimples04 There are other tests you can ask about.. definitely a 7 dpo progesterone and also an SA is a good start since it’s non-invasive. Also an ultrasound would be a good idea to check your AFC and check for any cysts or fibroids. Are you using OPKs and temping to confirm ovulation? 
    Me: 35 DH: 35
    TTC since 9/2018
    Dx: MFI
    10/19- First RE visit
    2/20- DH had surgery for bilateral varicoceles 
    7/20- IUI with 5 mg letrozole- BFN
    9/20- IVF. 9 eggs retrieved, 9 mature, 8 fertilized with ICSI, 7 blasts, 4 PGT-A normal
    11/20- Mock transfer/ERA
    12/20- FET #1- transferred one 4AB- BFN
    3/21- FET #2- transferred one 3AB- BFP! Due Dec 2021
    12/21- Baby girl born!

  • @misshelen86 I missed your post earlier. Sorry. ❤️ There is a lot of excitement in my family as well, which has made this a really emotional journey. I pray your lining is ready so you don’t need to cancel anything for this cycle. And yes, I have been using OPKs and temping since June, all of which suggest ovulation. 
    TTC History

    Me: 26 DH: 27

    TTC #1 | June '18-August '18 | DD | Born April 21, 2019 | Due May 10, 2019

    Lilypie Third Birthday tickers

    TTC#2 | June '20-February '21 | DS | Due October 27, 2021

    Lilypie Maternity tickers

  • laura-kaylaura-kay member
    edited December 2020
    I’m following along with everyone and rooting for you all, but there is so much I am still learning and trying to understand!  I want to respond to people but I feel like I am just trying to keep afloat right now lol. 

    Bloating and tenderness is really happening a lot.  I am hoping it doesn’t get even more painful.  I’m starting to really not look forward to the injections.

    I forgot to answer the questions earlier...

    Diagnosis (if you've been): Unexplained infertility   

    Status (WTO/TWW/TTA): WTO  

    What are you doing this cycle? (Testing? Treatment?): Gonal F, Ovidril, IUI

    How are things going?:  I’m feeling very bloated and uncomfortable.  I also am very tired and drained, both physically and emotionally.  My first monitoring ultrasound/ bloodwork visit is Thursday, so hopefully that will go well.

    Any questions?: I know bloating is normal, but is a “heaviness” and tenderness also normal?

    GTKY: Now that Thanksgiving is behind us, what is your favourite Christmas scent (what reminds you of Christmas when you smell it) and why?   Baking scents from many years of family baking together before Christmas!

    IF Journey

    2016 - actively trying to conceive
    2017 - initiated testing
    2018 - HSG with false diagnosis of blocked tubes; laparoscopy that overrode the HSG results showing that it wasn’t blocked, but did have some endometriosis; infertility diagnosis with unknown reasons
    2018 - a break for continuing to try naturally
    Early 2020 - Worked with an REI specialist to finalize testing and come up with treatment options
    Late November 2020 - began first IUI + superovulation treatment

  • laura-kaylaura-kay member
    edited December 2020
    Accidental post
  • @kiki047 I'm really sorry that you had such a rough month. Glad that December is finally hear and we all have 2021 to look forward to! I'm super happy to hear your RE is letting you do a true "mock" cycle. Throw everything you got at that lining of yours so you can get that sticky 2021 baby! Also, thank you for the tip re: priming the pump. Our IUI is on Thu, so no chance to practice. We HIO'ed yesterday, and by Thu, it will be 3 days of abstinence. I think we'll hold off on "priming the pump" for this cycle. But if another cycle is needed, I've got those instructions handy! The funny with your friend and her H is hilarious! 

    @gingermama29 definitely wait until you're in your TWW to do the SA. It really sucks that the clinic doesn't accept the semen samples on weekends; so difficult for us working folks! I really hope your OPKs start to turn soon; you're probably a slow responder like @runningoncookies so hang tight! It'll happen. If you need another cycle, I would definitely encourage monitoring which might require going to your RE. 

    @chindimples04 Did they test your LH, AMH and E2 results? If not, you should request them. Here's an article on what all these hormones mean and why they need to be tested on Day 3. I also agree with others that next step should be having YH get an SA, although a 7DPO progesterone check + an antral follicle count (AFC) on CD Days 2-4 is a good idea. Your FSH and TSH are both looking good though! 

    @runningoncookies only 2 more days until you can test! Hopefully you'll be happy with just pizza on Saturday night! FX. 

    @misshelen86 ooh! FET month is here! In addition to supplements, have you already started estrogen? I hope Dec 11 is here before you know it and that you get good news vis-a-vis your lining! I am sorry this is proving to be a stressful Christmas for you; hopefully you'll have _something_ to add to the celebratory time! FX. 

    @emmasemm super info! Thanks for popping by to share. 

    @laura-kay what are your medications and dosages? When are you going in for a monitoring u/s? 

    @krash_ I'm sorry you're having a rough go with the progesterone suppositories; it took me a while to get used to them. What's your dose? Oddly enough, I found the leaking really bad when I had to do 200mg AM AND 200mg PM (and the sore boobs were so awful for SS); last month I went down to 200mg in PM only and the "leaking" was definitely better. As for when / if to schedule your beta, I didn't bother last cycle even though we did TI; my clinic does a mandatory HCG / E2 test before starting a new medicated cycle, just to make sure I'm not pregnant before taking Clomid. Might be worthwhile checking what the procedure at your clinic is. Finally, I am sorry your PreTTI was so stressful. Hopefully it did the trick anyway! FX. 

    TTC History
    TTC#2
    Me: 41; MH: 40 | Met 02/2009 | Started Dating 08/2017 | Married 02/02/2020
    Mar 2024 | consult to get established with a new reproductive immunologist (Alan Beer Center)
    Apr/May 2024 | required testing & waiting for a protocol
    May 2024 | protocol given / decided to go back to my old reproductive immunologist, Dr. Jubiz
    Jun / Jul 2024 | more testing, incl. SIS, ultrasound, and endometrial biopsy
    Jul 2024 | Dx chronic endometritis; 14 days of 100mg of doxy given
    Sep 2024 | Repeat endometrial biopsy; still + for chronic endometritis. 2 more antibiotics + an antiviral
    Oct 2024 | Hysteroscopy turned polypectomy; endometriosis consult w/ specialist who confirmed high likelihood of endo based on symptoms and ultrasound; lots of blood tests ordered
    Mar 2025 | Endo excision surgery. Stage 3 endo found! Recoveing
    Apr 2025 | Planning transfer w/ RE & green light protocol w/ RI; target transfer July or August 2025
    May 2025 | Surprise BFP! EDD 1/11/2026


    TTC #1
    Me: 36, MH: 34 | Met 02/2009 | Started Dating 08/2017 | Married 02/02/2020
    TTC #1 02/2020 - 07/2022
    2009 | Dx PCOS; likely a misdiagnosis
    07/14/20 | Dx Hashimoto's Thyroditis
    07/21/20 | 1st RE appointment
    07/2120 - 08/20/20 | so much testing; no signs of PCOS
    08/20/20 | Dx Unexplained; AMA
    09/08/20 | IUI #1 Clomid + Trigger + Prometrium | BFN
    09/30/20 | Urology consult; more testing required
    10/2020 | Clomid + OPK + TI + Prometrium | BFN
    10/26/2020 | Starting 2nd IUI cycle, with Letrazole and with a new RE / different clinic
    11/03/2020 | New Dx "poor egg quality"; IUI cancelled in favor of Trigger + TI + Prometrium | BFN
    11/26/2020 | Combo IUI (Clomid + Menopur) + Trigger + Prometrium | BFN
    12/20/2020 | Combo IUI (Clomid + Gonal-F) + Trigger | IUI Cancelled due to thin lining; TI only | BFN
    01/14/2021 | Combo IUI (Letrazole + Menopur) + Trigger | BFN
    02/06/2021 | Switched to a new RE (TEW) ; trying naturally until we complete additional testing 
    03/14/2021 | Hybrid Double IUI, with Zymot (Letrazole, Gonal-F) + Trigger + Endometrin | Ovulated 4 mature eggs but still a BFN ☹️
    04/07/2021 | Natural cycle while we regroup | BFN
    04/09/2021 | Employer announces fertility benefits starting 05/01/2021! | Search for a new doctor who accepts insurance
    05/10/2021 | New RE consult & plan for IVF
    05/13/2021 | Mid-luteal IVF cycle #1 interrupted; had to get cancer genetic screening done to make sure I didn't have the same SDHA gene mutation as MH. 
    06/10/2021 | Aygestin priming IVF cycle #1; opted to Cx after 9 days of stims since only 5-6/12 follicles responded
    07/26/2021 | Attempt #2 at IVF cycle #1 (mid-luteal start): 8 retrieved, 8 MII, 6 fert (1 PN3), 3 Day 5 & 6 blasts: 3AA, 3AA, 6AB; 3 euploid
    08/09/2021 | Rest cycle / unmedicated TTC | Shockingly, a BFP! EDD: 5/25/202 | CP at 4w4d
    09/23/2021 | IVF cycle #2 (mid-luteal start): 14 retrieved, 13 MII, 11 fert, 5 Day 5 & 6 blasts: 2 x 3AA, 2 x 3AB, 3BB; 2 euploid
    11/12/2021 | IVF cycle #3 (mid-luteal start): cancelled due to ovaries being on vacation
    12/20/2021 | Rest cycle / unmedicated TTC + Pregmune Immunology Testing; BFN
    01/22/2022 | Rest cycle / unmedicated TTC + understanding uncovered immunological issues; BFN
    02/18/2022 | Mock transfer cycle! ERA, ReceptivaDx, EMMA/ALICE; start Prednisone to address NK activity
    03/16/2022 | Final, "Hail Mary" super-ovulation + TI cycle before FET; BFP! EDD: 12/21/2022 | MMC 05/08/2022
    05/20/2022 | D&C; recovering... 
    06/21/2022 | Trying naturally until October 2022
    07/21/2022 | BFP! EDD 04/02/2023; 👦🏼 born on 4/5/2023


  • @acleverusername 150iu daily.  My first monitoring visit is Thursday 
  • @acleverusername That’s an interesting concept for the combination IUI + superovulation.  I hadn’t heard of that form of treatment; it sounds like a good way to balance cost, side effects and efficacy.
  • @acleverusername I’m so happy to hear how well your u/a went and that you can continue to move forward with this cycle! 🤞🏼

    @kiki047 I was VERY hesitant to even begin posting here in the first place because of my history and the journeys of the others on this thread. I felt that my TW was pertinent to the conversation as it gave further explanation to the situation. Perhaps my journey isn’t best posted here.
    TTC History

    Me: 26 DH: 27

    TTC #1 | June '18-August '18 | DD | Born April 21, 2019 | Due May 10, 2019

    Lilypie Third Birthday tickers

    TTC#2 | June '20-February '21 | DS | Due October 27, 2021

    Lilypie Maternity tickers

  • @laura-kay I’m doing the combo IUI (or hybrid IUI as Egg Whisperer calls it) is exactly for cost savings plus a lower chance of too many follicles which often happens with straight injectables. There’s oddly very little information about these types of cycles. Like I said, if I weren’t a fervent listener of TEH podcast I wouldn’t have known to ask for it. Then I knew the key words to search for. If you want to read more about others’ experience, google “combo IUI the bump” or “combo IUI babycenter.”

    Good luck on Thursday! What CD will it be?

    Also, I’m still really interested in learning more about you, YH, and your fertility journey this far. Don’t feel shy to into yourself in the weekly Newbie Intro thread.

    @chindimples04 the last thing we want to do is make this place feel unwelcome to new joiners. In the thread intro, it says “place for those of us who have already started TTC, but have started infertility testing and/or treatments.” It is, however, hard for long-timers (and I don’t consider myself one since I’ve only been at this for 11 months) who are at very different stages of the journey to see TW LCs since many on here are trying for their first. I agree with you that your TW LC was pertinent to the convo, but I think I would just say that here, instead of using TWs it’s almost better to send a PM to a specific poster with additional info and just respond with YGPM. 

    It too took me a while to learn the lay of the IF land and I think you WILL benefit from being here. For example, I know many here suggested the next step would be to have YH do an SA... would you have known to do that if you didn’t ask that question? Anyway, I don’t mean to lecture but I do want to make sure all feel welcome. 

    TTC History
    TTC#2
    Me: 41; MH: 40 | Met 02/2009 | Started Dating 08/2017 | Married 02/02/2020
    Mar 2024 | consult to get established with a new reproductive immunologist (Alan Beer Center)
    Apr/May 2024 | required testing & waiting for a protocol
    May 2024 | protocol given / decided to go back to my old reproductive immunologist, Dr. Jubiz
    Jun / Jul 2024 | more testing, incl. SIS, ultrasound, and endometrial biopsy
    Jul 2024 | Dx chronic endometritis; 14 days of 100mg of doxy given
    Sep 2024 | Repeat endometrial biopsy; still + for chronic endometritis. 2 more antibiotics + an antiviral
    Oct 2024 | Hysteroscopy turned polypectomy; endometriosis consult w/ specialist who confirmed high likelihood of endo based on symptoms and ultrasound; lots of blood tests ordered
    Mar 2025 | Endo excision surgery. Stage 3 endo found! Recoveing
    Apr 2025 | Planning transfer w/ RE & green light protocol w/ RI; target transfer July or August 2025
    May 2025 | Surprise BFP! EDD 1/11/2026


    TTC #1
    Me: 36, MH: 34 | Met 02/2009 | Started Dating 08/2017 | Married 02/02/2020
    TTC #1 02/2020 - 07/2022
    2009 | Dx PCOS; likely a misdiagnosis
    07/14/20 | Dx Hashimoto's Thyroditis
    07/21/20 | 1st RE appointment
    07/2120 - 08/20/20 | so much testing; no signs of PCOS
    08/20/20 | Dx Unexplained; AMA
    09/08/20 | IUI #1 Clomid + Trigger + Prometrium | BFN
    09/30/20 | Urology consult; more testing required
    10/2020 | Clomid + OPK + TI + Prometrium | BFN
    10/26/2020 | Starting 2nd IUI cycle, with Letrazole and with a new RE / different clinic
    11/03/2020 | New Dx "poor egg quality"; IUI cancelled in favor of Trigger + TI + Prometrium | BFN
    11/26/2020 | Combo IUI (Clomid + Menopur) + Trigger + Prometrium | BFN
    12/20/2020 | Combo IUI (Clomid + Gonal-F) + Trigger | IUI Cancelled due to thin lining; TI only | BFN
    01/14/2021 | Combo IUI (Letrazole + Menopur) + Trigger | BFN
    02/06/2021 | Switched to a new RE (TEW) ; trying naturally until we complete additional testing 
    03/14/2021 | Hybrid Double IUI, with Zymot (Letrazole, Gonal-F) + Trigger + Endometrin | Ovulated 4 mature eggs but still a BFN ☹️
    04/07/2021 | Natural cycle while we regroup | BFN
    04/09/2021 | Employer announces fertility benefits starting 05/01/2021! | Search for a new doctor who accepts insurance
    05/10/2021 | New RE consult & plan for IVF
    05/13/2021 | Mid-luteal IVF cycle #1 interrupted; had to get cancer genetic screening done to make sure I didn't have the same SDHA gene mutation as MH. 
    06/10/2021 | Aygestin priming IVF cycle #1; opted to Cx after 9 days of stims since only 5-6/12 follicles responded
    07/26/2021 | Attempt #2 at IVF cycle #1 (mid-luteal start): 8 retrieved, 8 MII, 6 fert (1 PN3), 3 Day 5 & 6 blasts: 3AA, 3AA, 6AB; 3 euploid
    08/09/2021 | Rest cycle / unmedicated TTC | Shockingly, a BFP! EDD: 5/25/202 | CP at 4w4d
    09/23/2021 | IVF cycle #2 (mid-luteal start): 14 retrieved, 13 MII, 11 fert, 5 Day 5 & 6 blasts: 2 x 3AA, 2 x 3AB, 3BB; 2 euploid
    11/12/2021 | IVF cycle #3 (mid-luteal start): cancelled due to ovaries being on vacation
    12/20/2021 | Rest cycle / unmedicated TTC + Pregmune Immunology Testing; BFN
    01/22/2022 | Rest cycle / unmedicated TTC + understanding uncovered immunological issues; BFN
    02/18/2022 | Mock transfer cycle! ERA, ReceptivaDx, EMMA/ALICE; start Prednisone to address NK activity
    03/16/2022 | Final, "Hail Mary" super-ovulation + TI cycle before FET; BFP! EDD: 12/21/2022 | MMC 05/08/2022
    05/20/2022 | D&C; recovering... 
    06/21/2022 | Trying naturally until October 2022
    07/21/2022 | BFP! EDD 04/02/2023; 👦🏼 born on 4/5/2023


  • @acleverusername I am clearly still learning the “rules”. I spent a lot of time lurking before posting, so I really thought I was doing things right. I will keep the YGPM in mind. I honestly am just figuring out what that means. 🙈 There was a lot they didn’t run that I was surprised about. They only ran TSH, PDG, and FSH, perhaps because I’m still early in the game.

     I am really sorry if anything I said or did was triggering. That wasn’t my intention at all.

    @kiki047 to answer many of your other questions, I am not being seen by an OB or RE. I don’t have established care with an OB right now, just with the CNMs at my clinic. That may be part of my “issue” getting support for bloodwork. However, the CNMs consult with OBs when ordering and reading bw and they all agreed that after 6 cycles of TI, OPKS, BBT, tracking and charting, extra vitamins, and an extremely healthy diet, bw was the correct next step. Because of this, I’m not really sure where to ask about doing an SA. To answer your other question, I’ll just PM you.
    TTC History

    Me: 26 DH: 27

    TTC #1 | June '18-August '18 | DD | Born April 21, 2019 | Due May 10, 2019

    Lilypie Third Birthday tickers

    TTC#2 | June '20-February '21 | DS | Due October 27, 2021

    Lilypie Maternity tickers

  • @chindimples04 if you want to get tested for everything, but your CNM isn't willing to order the tests, you can look into Modern Fertility at home hormone test kit. It's about $160 and you'll get the whole she-bang. Full disclosure, even though I have no financially-beneficial association with the company, I've been a big supporter of theirs since Aug 2018, when I first stumbled across them. And I also lead their TTC35+ Slack channel and I'm on their customer advisory board. 

    TTC History
    TTC#2
    Me: 41; MH: 40 | Met 02/2009 | Started Dating 08/2017 | Married 02/02/2020
    Mar 2024 | consult to get established with a new reproductive immunologist (Alan Beer Center)
    Apr/May 2024 | required testing & waiting for a protocol
    May 2024 | protocol given / decided to go back to my old reproductive immunologist, Dr. Jubiz
    Jun / Jul 2024 | more testing, incl. SIS, ultrasound, and endometrial biopsy
    Jul 2024 | Dx chronic endometritis; 14 days of 100mg of doxy given
    Sep 2024 | Repeat endometrial biopsy; still + for chronic endometritis. 2 more antibiotics + an antiviral
    Oct 2024 | Hysteroscopy turned polypectomy; endometriosis consult w/ specialist who confirmed high likelihood of endo based on symptoms and ultrasound; lots of blood tests ordered
    Mar 2025 | Endo excision surgery. Stage 3 endo found! Recoveing
    Apr 2025 | Planning transfer w/ RE & green light protocol w/ RI; target transfer July or August 2025
    May 2025 | Surprise BFP! EDD 1/11/2026


    TTC #1
    Me: 36, MH: 34 | Met 02/2009 | Started Dating 08/2017 | Married 02/02/2020
    TTC #1 02/2020 - 07/2022
    2009 | Dx PCOS; likely a misdiagnosis
    07/14/20 | Dx Hashimoto's Thyroditis
    07/21/20 | 1st RE appointment
    07/2120 - 08/20/20 | so much testing; no signs of PCOS
    08/20/20 | Dx Unexplained; AMA
    09/08/20 | IUI #1 Clomid + Trigger + Prometrium | BFN
    09/30/20 | Urology consult; more testing required
    10/2020 | Clomid + OPK + TI + Prometrium | BFN
    10/26/2020 | Starting 2nd IUI cycle, with Letrazole and with a new RE / different clinic
    11/03/2020 | New Dx "poor egg quality"; IUI cancelled in favor of Trigger + TI + Prometrium | BFN
    11/26/2020 | Combo IUI (Clomid + Menopur) + Trigger + Prometrium | BFN
    12/20/2020 | Combo IUI (Clomid + Gonal-F) + Trigger | IUI Cancelled due to thin lining; TI only | BFN
    01/14/2021 | Combo IUI (Letrazole + Menopur) + Trigger | BFN
    02/06/2021 | Switched to a new RE (TEW) ; trying naturally until we complete additional testing 
    03/14/2021 | Hybrid Double IUI, with Zymot (Letrazole, Gonal-F) + Trigger + Endometrin | Ovulated 4 mature eggs but still a BFN ☹️
    04/07/2021 | Natural cycle while we regroup | BFN
    04/09/2021 | Employer announces fertility benefits starting 05/01/2021! | Search for a new doctor who accepts insurance
    05/10/2021 | New RE consult & plan for IVF
    05/13/2021 | Mid-luteal IVF cycle #1 interrupted; had to get cancer genetic screening done to make sure I didn't have the same SDHA gene mutation as MH. 
    06/10/2021 | Aygestin priming IVF cycle #1; opted to Cx after 9 days of stims since only 5-6/12 follicles responded
    07/26/2021 | Attempt #2 at IVF cycle #1 (mid-luteal start): 8 retrieved, 8 MII, 6 fert (1 PN3), 3 Day 5 & 6 blasts: 3AA, 3AA, 6AB; 3 euploid
    08/09/2021 | Rest cycle / unmedicated TTC | Shockingly, a BFP! EDD: 5/25/202 | CP at 4w4d
    09/23/2021 | IVF cycle #2 (mid-luteal start): 14 retrieved, 13 MII, 11 fert, 5 Day 5 & 6 blasts: 2 x 3AA, 2 x 3AB, 3BB; 2 euploid
    11/12/2021 | IVF cycle #3 (mid-luteal start): cancelled due to ovaries being on vacation
    12/20/2021 | Rest cycle / unmedicated TTC + Pregmune Immunology Testing; BFN
    01/22/2022 | Rest cycle / unmedicated TTC + understanding uncovered immunological issues; BFN
    02/18/2022 | Mock transfer cycle! ERA, ReceptivaDx, EMMA/ALICE; start Prednisone to address NK activity
    03/16/2022 | Final, "Hail Mary" super-ovulation + TI cycle before FET; BFP! EDD: 12/21/2022 | MMC 05/08/2022
    05/20/2022 | D&C; recovering... 
    06/21/2022 | Trying naturally until October 2022
    07/21/2022 | BFP! EDD 04/02/2023; 👦🏼 born on 4/5/2023


  • @chindimples04 I have no problem if you post here since you are starting some testing. Just keep in mind that you are still early in your journey and it can take a healthy couple 6-12 months to conceive. I hope you are not sending @kiki047 a pm with the question she asked in the spoiler since she was very clear that she was asking only to give you some things to think about. Responding to those questions through a pm could be very triggering. 
    Me: 35 DH: 35
    TTC since 9/2018
    Dx: MFI
    10/19- First RE visit
    2/20- DH had surgery for bilateral varicoceles 
    7/20- IUI with 5 mg letrozole- BFN
    9/20- IVF. 9 eggs retrieved, 9 mature, 8 fertilized with ICSI, 7 blasts, 4 PGT-A normal
    11/20- Mock transfer/ERA
    12/20- FET #1- transferred one 4AB- BFN
    3/21- FET #2- transferred one 3AB- BFP! Due Dec 2021
    12/21- Baby girl born!

  • @acleverusername Yay for Thursday IUI!! Rooting for you so hard! Here in Canada, a 75 IU vial was about $200 for me but our insurance did cover a good portion. I can’t find the receipt for the 150 UI vial right now but I’m guessing is was about $400. 

    @laura-kay GL with your monitoring appointment tomorrow! Let us know how it goes
    Me: 35 DH: 35
    TTC since 9/2018
    Dx: MFI
    10/19- First RE visit
    2/20- DH had surgery for bilateral varicoceles 
    7/20- IUI with 5 mg letrozole- BFN
    9/20- IVF. 9 eggs retrieved, 9 mature, 8 fertilized with ICSI, 7 blasts, 4 PGT-A normal
    11/20- Mock transfer/ERA
    12/20- FET #1- transferred one 4AB- BFN
    3/21- FET #2- transferred one 3AB- BFP! Due Dec 2021
    12/21- Baby girl born!

  • @misshelen86 FX for a nice thick lining on the 11th!!

    @krash_ I’m totally with you on hating the suppositories! I didn’t mind them when I was just doing them at night, but now that I’m doing them in the morning too I feel gross all day. 

    @chindimples04 I’m sorry that you’re feeling frustrated with your test results not giving you the answers/clarification you had hoped for.

    @laura-kay good luck at your monitoring appointment tomorrow!!

    @acleverusername I’m just constantly amazed at your quick follie responses lol!! Sorry you didn’t get as many as you hoped, but FX for a successful IUI tomorrow!!
  • @kiki047 Not related to implantation, but The Egg Whisperer mentioned naltraxone on yesterday's show, and basically said "don't ask me how it works." I'm sure @keikilove knows all about how to get a better response in IVF cycles, but this question / answer really gets into the weeds. Start at 23:40. 


    TTC History
    TTC#2
    Me: 41; MH: 40 | Met 02/2009 | Started Dating 08/2017 | Married 02/02/2020
    Mar 2024 | consult to get established with a new reproductive immunologist (Alan Beer Center)
    Apr/May 2024 | required testing & waiting for a protocol
    May 2024 | protocol given / decided to go back to my old reproductive immunologist, Dr. Jubiz
    Jun / Jul 2024 | more testing, incl. SIS, ultrasound, and endometrial biopsy
    Jul 2024 | Dx chronic endometritis; 14 days of 100mg of doxy given
    Sep 2024 | Repeat endometrial biopsy; still + for chronic endometritis. 2 more antibiotics + an antiviral
    Oct 2024 | Hysteroscopy turned polypectomy; endometriosis consult w/ specialist who confirmed high likelihood of endo based on symptoms and ultrasound; lots of blood tests ordered
    Mar 2025 | Endo excision surgery. Stage 3 endo found! Recoveing
    Apr 2025 | Planning transfer w/ RE & green light protocol w/ RI; target transfer July or August 2025
    May 2025 | Surprise BFP! EDD 1/11/2026


    TTC #1
    Me: 36, MH: 34 | Met 02/2009 | Started Dating 08/2017 | Married 02/02/2020
    TTC #1 02/2020 - 07/2022
    2009 | Dx PCOS; likely a misdiagnosis
    07/14/20 | Dx Hashimoto's Thyroditis
    07/21/20 | 1st RE appointment
    07/2120 - 08/20/20 | so much testing; no signs of PCOS
    08/20/20 | Dx Unexplained; AMA
    09/08/20 | IUI #1 Clomid + Trigger + Prometrium | BFN
    09/30/20 | Urology consult; more testing required
    10/2020 | Clomid + OPK + TI + Prometrium | BFN
    10/26/2020 | Starting 2nd IUI cycle, with Letrazole and with a new RE / different clinic
    11/03/2020 | New Dx "poor egg quality"; IUI cancelled in favor of Trigger + TI + Prometrium | BFN
    11/26/2020 | Combo IUI (Clomid + Menopur) + Trigger + Prometrium | BFN
    12/20/2020 | Combo IUI (Clomid + Gonal-F) + Trigger | IUI Cancelled due to thin lining; TI only | BFN
    01/14/2021 | Combo IUI (Letrazole + Menopur) + Trigger | BFN
    02/06/2021 | Switched to a new RE (TEW) ; trying naturally until we complete additional testing 
    03/14/2021 | Hybrid Double IUI, with Zymot (Letrazole, Gonal-F) + Trigger + Endometrin | Ovulated 4 mature eggs but still a BFN ☹️
    04/07/2021 | Natural cycle while we regroup | BFN
    04/09/2021 | Employer announces fertility benefits starting 05/01/2021! | Search for a new doctor who accepts insurance
    05/10/2021 | New RE consult & plan for IVF
    05/13/2021 | Mid-luteal IVF cycle #1 interrupted; had to get cancer genetic screening done to make sure I didn't have the same SDHA gene mutation as MH. 
    06/10/2021 | Aygestin priming IVF cycle #1; opted to Cx after 9 days of stims since only 5-6/12 follicles responded
    07/26/2021 | Attempt #2 at IVF cycle #1 (mid-luteal start): 8 retrieved, 8 MII, 6 fert (1 PN3), 3 Day 5 & 6 blasts: 3AA, 3AA, 6AB; 3 euploid
    08/09/2021 | Rest cycle / unmedicated TTC | Shockingly, a BFP! EDD: 5/25/202 | CP at 4w4d
    09/23/2021 | IVF cycle #2 (mid-luteal start): 14 retrieved, 13 MII, 11 fert, 5 Day 5 & 6 blasts: 2 x 3AA, 2 x 3AB, 3BB; 2 euploid
    11/12/2021 | IVF cycle #3 (mid-luteal start): cancelled due to ovaries being on vacation
    12/20/2021 | Rest cycle / unmedicated TTC + Pregmune Immunology Testing; BFN
    01/22/2022 | Rest cycle / unmedicated TTC + understanding uncovered immunological issues; BFN
    02/18/2022 | Mock transfer cycle! ERA, ReceptivaDx, EMMA/ALICE; start Prednisone to address NK activity
    03/16/2022 | Final, "Hail Mary" super-ovulation + TI cycle before FET; BFP! EDD: 12/21/2022 | MMC 05/08/2022
    05/20/2022 | D&C; recovering... 
    06/21/2022 | Trying naturally until October 2022
    07/21/2022 | BFP! EDD 04/02/2023; 👦🏼 born on 4/5/2023


  • @acleverusername I posted a brief intro a few weeks ago (I think it was the last day of the week though), but I’d be happy to share more.  Unfortunately there isn’t an intro thread this week!
  • @laura-kay I just created one! 
    *TW LC*
    Me & MH: 32
    DS: 6/1/18 (Pre-E; IUGR; seizures; NICU)
    TTC #2: 12/2019
    Sept 2020: HSG possible blocked right tube
    Nov 2020: Letrozole + TI - BFN
    Dec 2020: Letrozole + TI - BFP!!! EDD 9/18

  • We had the first monitoring appointment.  My estradiol is 337 pg/mL.  I have two primary follicles plus some small ones under 10mm.  One was 12mm and the other was 13mm.  It seems big for just day 6, but I’m not a doctor, so I’m trying not to read into things.  It is so tempting to Google medicine and analyze every result.
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