Low Progesterone during last miscarriage? — The Bump
TTC After a Loss

Low Progesterone during last miscarriage?

Hi All, During my miscarriage in sept. I experienced low Progesterone. Is this something I should be concerned with now TTC ?? Did anyone else experience  this as well Or have to take supplements ? 

Re: Low Progesterone during last miscarriage?

  • @mamatohayleygirl That is definitely something you should discuss with your RE, or OB. It's something that should be tested for if you qualify for RPL testing.  If not, and you've only had the one loss, especially if you have any living children at home, it could have just been a fluke or something with the last PG.  Or it could have been that the number had already dropped because you were losing the PG when the number was tested for.  I would definitely discuss your concerns with your doctor!
  • Seconding what @capnjackharkness said. It's definitely worth talking about with your doctor. My loss last month started off fine, my progesterone was in the 20s a week after my first BFP. 2 weeks later when I had an US it had dropped to 7. I meet with my OB next week and will ask her about supplementing with progesterone as soon as so get a BFP to see if it helps.

    I know there is also some debate if low progesterone causes MC or if an impending MC causes the progesterone to drop. 

    With TTC, progesterone is only an issue if you have a short luteal phase. Progesterone drops at the onset of your period and sometimes that doesn't give an embryo enough time to reach the uterus and implant. Some women don't produce enough progesterone at all while others have progesterone that drops too early.

    How that help and good luck!
    *TW* History:
    Me: 32 DH: 34 | Together since 2007 | Married July 2016

    TTC #1 since 7.2017
    Dx: low morph (1%), ANA positive, low decidualization score, high TSH and testosterone, histone antibodies

    IUI #1-3 all BFN
    IVF #1 | 6.11.19 | 24R, 17M, 15F, 6B, PGT-A tested - 5 normal, 3 girls & 2 boys
    FET #1 | 9.10.19 | BFN "I know you, but we've never met. I'm with you, but I don't know your name"
    RPL, Receptiva, & ERA testing | all normal/negative, recommended going on gluten and dairy free diet for next FET
    FET #2 | 3.31.20 | Opted to cancelled due to pandemic, continued diet and tried naturally over the summer
    2nd Opinion with another RE | 8.20.20 | Not immune to measles (received 1 dose); SA results similar to 2 years ago; decided to move forward with FET #2 redo at start of next cycle
    Surprise natural BFP! | 9.22.20 | MC 10.23.20 at 8 weeks
    TTCAL naturally | starting 11.22.20
    Attempted antihistamine protocol | 6.18.21 | BFN
    The long shot "I think vaccines can help me get pregnant" protocol | Covid vaccine shot #1 7.30.21; shot #2 8.20.21
    Initial consultation with Reproductive Immunologist | 9.14.21
    Decidualization score biopsy | 10.1.21 | abnormal - low score of 1; endometrial scratch recommended and progesterone supplementation
    Saline sono | 10.15.21 | normal
    Bloodwork | 10.21.21 high TSH, high testosterone, positive for anti-nuclear antibodies and histone antibodies
    BFP! | 11.3.21 | EDD 7.14.22 B) | biopsy provided same effect as endometrial scratch; added supplemental progesterone and estrogen, prednisone, levothyroxine, and MTX to maintain pregnancy
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