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IF Testing & Treament w/o 7/13

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Re: IF Testing & Treament w/o 7/13

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    @bluetickgal Haha Gonal-F was his favorite because it was the easiest to administer - no mixing and air bubbles were minimal with the pen. Also, the needle is the smallest! And yes, at one point when we were having issues getting approvals to get started with IVF he literally told me "I just want to be able to stab you with needles, is that too much to ask?!" :D:D:D:D He's funny like that. 

    @avidlyuks36 Welcome! I'm sorry you find yourself here, but hopefully this IUI will have a great result! 
    me: 35 / so: 34 | ttc #1 since 9/2018
    DX: MFI
    IVF Cycle #1 February 2020 4 embryos frozen, 1 fresh transfer = CP 
    FET #1 Natural Cycle March 2020 CXL'd due to Covid-19 :( 
    FET #1 Natural Cycle June 2020 - CP #2
    FET #2 Natural Cycle July 2020 - BFP!!!!!! Beta #1 = 273


    June Signature Challenge - Favorite TV Quotes


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    @mvt2003 I feel like I remember you posting that a while back, about YH just wanting to stab you with needles hahahaha At least he's honest  :D:D   I'm not doing Gonal-F (RE flat out told me NO haha) but I am curious for my gal @bluetickgal - since you said it's the smallest, would you say it's similar to the trigger? Cause that was pretty little and painless.
    Our TTC Journey
    TTC #1: May 2011
    BFP: 10/27/2011 |  EDD: 6/30/12
    DS born 6/28/12 via C/S 3 

    TTC #2: September 2018
    Me: 36 | DH: 39
    Mirena removed 9/13/2018 after 6 years
    BFP 11/11/2018 | MC @ 5.5 weeks on Thanksgiving
    July 2019 - Diagnosed with Secondary Unexplained IF
    August 2019 - 2.5 mg of Letrozole = Never Ovulated so Trigger and IUI were cancelled
    9/30/2019 - IUI #1 (5 mg of Letrozole + Trigger) =  BFP but Betas showed CP @ 4 weeks
    10/28/2019 - IUI #2 (7.5mg of Letrozole + Trigger) = BFN
    11/25/2019 - IUI #3 (7.5mg of Letrozole, Trigger + Crinone after IUI) = BFN
    12/24/2019 - IUI #4 (7.5mg of Letrozole + Crinone after IUI) = BFN
    1/24/2020 - IUI #5 (50mg of Clomid + Trigger + Crinone after IUI) = BFN and an Ovarian Cyst
    3/2/2020 - Taking a break to reset/NTNP
    11/1/2020 - At peace with where things are in life and are no long actively TTC. Whatever happens will happen and it will all be okay. <3

  • Options
    @kpearse99 Haha he's always honest like that! The Gonal-F needle was IMO even smaller than my Ovidrel trigger! Cetrotide was my least fave! 
    me: 35 / so: 34 | ttc #1 since 9/2018
    DX: MFI
    IVF Cycle #1 February 2020 4 embryos frozen, 1 fresh transfer = CP 
    FET #1 Natural Cycle March 2020 CXL'd due to Covid-19 :( 
    FET #1 Natural Cycle June 2020 - CP #2
    FET #2 Natural Cycle July 2020 - BFP!!!!!! Beta #1 = 273


    June Signature Challenge - Favorite TV Quotes


  • Options
    @mvt2003 sounds great! They mentioned Menopur as an option, but the nurse said that is more complicated with having to mix it...so I’m glad I’m be going with one of the other two! Bahaha to YH...sometimes you just need to stab things! 😂 I may have DH do some of these injections...he offered with the trigger, but I figured it would be easier myself for just one shot in the belly! @kpearse99 thanks for always looking out for me, friend! It’s hard to imagine a needle smaller than the trigger shot, but I’ll take it! 
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    legallykatelegallykate member
    edited July 2020
    I wish they were all pens! The pens and dosing seem so user friendly, get on board other meds. @mvt2003 the Cetrotide gives me an itchy welt but my nurse said that's super common. I'm not sure whether I dislike that or the burning of the Menopur more though. Glad to hear the trigger shot isn't bad!
    *TTC History*

    Me: 37, MH: 38; Married August 2017

    TTC #1 October 2017: BFP on 12/1/2017, DD born 7/24/2018 @ 37+1 after induction due to preeclampsia

    TTC #2 January 2020: AMA, dx with DOR in May 2020

    IVF July 2020: 16 eggs retrieved, 14 mature, 12 fertilized, 3 blasts, 2 PGT-A normal

    FET 10/7/20: BFP on 10/12/20!!! (EDD 6/25/21); First beta 10/16/20 (9dpt): 148; Second beta 10/19/20 (12dpt): 621; Third beta 10/26/20 (19dpt): 4732; Fourth (and final!) beta 11/2/20 (26 dpt): 22,000+

  • Options
    I need some advice... not sure if anyone here has thyroid issues. I recently got tested and it looks like I have Hashimoto's. Yesterday I had 1st of many fertility-related appointments booked for this month; this one with a specialist OB at my own OBGYN clinic. She is starting me off on thyroid meds right away (note: my TSH isn't bad yet @ 3.36, though I know for TTC it ought to be below 2.5) and has recommended I continue to be followed by an endocrinologist for it since it transcends TTC. She's also starting me on progesterone supplementation in luteal phase, given my low progesterone. Finally, since it's been 6 months, she is recommending that we try a few medicated cycles + timed intercourse before going down a more aggressive RE path. She even said that she could do IUI at the clinic (and I'm hoping doing this through her would cost less since my insurance doesn't cover an infertility treatments). So, where I am hesitating right now is going on 3 different medications all in one cycle: Prometrium, Levothyroxine + Letrazole (or Clomid). I'm wondering if I should get my thyroid under control first, and then go for Letrazole. This would likely mean August will be more of what we've been doing thus far, and starting medicated cycles in Sep. Any advice?
    MY CHART
    TTC History
    TTC#2
    Me: 40.5; MH: 39 | Met 02/2009 | Started Dating 08/2017 | Married 02/02/2020
    TTC #2 ... preparing as of March 2024


    TTC #1
    Me: 36, MH: 34 | Met 02/2009 | Started Dating 08/2017 | Married 02/02/2020
    TTC #1 02/2020 - 07/2022
    2009 | Dx PCOS; likely a misdiagnosis
    07/14/20 | Dx Hashimoto's Thyroditis
    07/21/20 | 1st RE appointment
    07/2120 - 08/20/20 | so much testing; no signs of PCOS
    08/20/20 | Dx Unexplained; AMA
    09/08/20 | IUI #1 Clomid + Trigger + Prometrium | BFN
    09/30/20 | Urology consult; more testing required
    10/2020 | Clomid + OPK + TI + Prometrium | BFN
    10/26/2020 | Starting 2nd IUI cycle, with Letrazole and with a new RE / different clinic
    11/03/2020 | New Dx "poor egg quality"; IUI cancelled in favor of Trigger + TI + Prometrium | BFN
    11/26/2020 | Combo IUI (Clomid + Menopur) + Trigger + Prometrium | BFN
    12/20/2020 | Combo IUI (Clomid + Gonal-F) + Trigger | IUI Cancelled due to thin lining; TI only | BFN
    01/14/2021 | Combo IUI (Letrazole + Menopur) + Trigger | BFN
    02/06/2021 | Switched to a new RE (TEW) ; trying naturally until we complete additional testing 
    03/14/2021 | Hybrid Double IUI, with Zymot (Letrazole, Gonal-F) + Trigger + Endometrin | Ovulated 4 mature eggs but still a BFN ☹️
    04/07/2021 | Natural cycle while we regroup | BFN
    04/09/2021 | Employer announces fertility benefits starting 05/01/2021! | Search for a new doctor who accepts insurance
    05/10/2021 | New RE consult & plan for IVF
    05/13/2021 | Mid-luteal IVF cycle #1 interrupted; had to get cancer genetic screening done to make sure I didn't have the same SDHA gene mutation as MH. 
    06/10/2021 | Aygestin priming IVF cycle #1; opted to Cx after 9 days of stims since only 5-6/12 follicles responded
    07/26/2021 | Attempt #2 at IVF cycle #1 (mid-luteal start): 8 retrieved, 8 MII, 6 fert (1 PN3), 3 Day 5 & 6 blasts: 3AA, 3AA, 6AB; 3 euploid
    08/09/2021 | Rest cycle / unmedicated TTC | Shockingly, a BFP! EDD: 5/25/202 | CP at 4w4d
    09/23/2021 | IVF cycle #2 (mid-luteal start): 14 retrieved, 13 MII, 11 fert, 5 Day 5 & 6 blasts: 2 x 3AA, 2 x 3AB, 3BB; 2 euploid
    11/12/2021 | IVF cycle #3 (mid-luteal start): cancelled due to ovaries being on vacation
    12/20/2021 | Rest cycle / unmedicated TTC + Pregmune Immunology Testing; BFN
    01/22/2022 | Rest cycle / unmedicated TTC + understanding uncovered immunological issues; BFN
    02/18/2022 | Mock transfer cycle! ERA, ReceptivaDx, EMMA/ALICE; start Prednisone to address NK activity
    03/16/2022 | Final, "Hail Mary" super-ovulation + TI cycle before FET; BFP! EDD: 12/21/2022 | MMC 05/08/2022
    05/20/2022 | D&C; recovering... 
    06/21/2022 | Trying naturally until October 2022
    07/21/2022 | BFP! EDD 04/02/2023; 👦🏼 born on 4/5/2023


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    @bluetickgal that bit about putting money into adoption makes so much sense! I think I'm going to keep 1 RE appointment to get a "2nd opinion" but punt all others. Other than thyroid, other Day 3 hormones looked good as did a recent, CD12 u/s and FX that postponing these convos by 3-4 months won't change that. 

    @mvt2003 seriously LOL'ing about the stabbing bit. MH is afraid of needles so I'm not sure I could ever count on him to do any kind of drug administration for me. Is the trigger shot the one that goes in the butt? 

    @kpearse99 what was your protocol if not Gonal-f?

    @legallykate agreed that the pen is super easy to use. 
    MY CHART
    TTC History
    TTC#2
    Me: 40.5; MH: 39 | Met 02/2009 | Started Dating 08/2017 | Married 02/02/2020
    TTC #2 ... preparing as of March 2024


    TTC #1
    Me: 36, MH: 34 | Met 02/2009 | Started Dating 08/2017 | Married 02/02/2020
    TTC #1 02/2020 - 07/2022
    2009 | Dx PCOS; likely a misdiagnosis
    07/14/20 | Dx Hashimoto's Thyroditis
    07/21/20 | 1st RE appointment
    07/2120 - 08/20/20 | so much testing; no signs of PCOS
    08/20/20 | Dx Unexplained; AMA
    09/08/20 | IUI #1 Clomid + Trigger + Prometrium | BFN
    09/30/20 | Urology consult; more testing required
    10/2020 | Clomid + OPK + TI + Prometrium | BFN
    10/26/2020 | Starting 2nd IUI cycle, with Letrazole and with a new RE / different clinic
    11/03/2020 | New Dx "poor egg quality"; IUI cancelled in favor of Trigger + TI + Prometrium | BFN
    11/26/2020 | Combo IUI (Clomid + Menopur) + Trigger + Prometrium | BFN
    12/20/2020 | Combo IUI (Clomid + Gonal-F) + Trigger | IUI Cancelled due to thin lining; TI only | BFN
    01/14/2021 | Combo IUI (Letrazole + Menopur) + Trigger | BFN
    02/06/2021 | Switched to a new RE (TEW) ; trying naturally until we complete additional testing 
    03/14/2021 | Hybrid Double IUI, with Zymot (Letrazole, Gonal-F) + Trigger + Endometrin | Ovulated 4 mature eggs but still a BFN ☹️
    04/07/2021 | Natural cycle while we regroup | BFN
    04/09/2021 | Employer announces fertility benefits starting 05/01/2021! | Search for a new doctor who accepts insurance
    05/10/2021 | New RE consult & plan for IVF
    05/13/2021 | Mid-luteal IVF cycle #1 interrupted; had to get cancer genetic screening done to make sure I didn't have the same SDHA gene mutation as MH. 
    06/10/2021 | Aygestin priming IVF cycle #1; opted to Cx after 9 days of stims since only 5-6/12 follicles responded
    07/26/2021 | Attempt #2 at IVF cycle #1 (mid-luteal start): 8 retrieved, 8 MII, 6 fert (1 PN3), 3 Day 5 & 6 blasts: 3AA, 3AA, 6AB; 3 euploid
    08/09/2021 | Rest cycle / unmedicated TTC | Shockingly, a BFP! EDD: 5/25/202 | CP at 4w4d
    09/23/2021 | IVF cycle #2 (mid-luteal start): 14 retrieved, 13 MII, 11 fert, 5 Day 5 & 6 blasts: 2 x 3AA, 2 x 3AB, 3BB; 2 euploid
    11/12/2021 | IVF cycle #3 (mid-luteal start): cancelled due to ovaries being on vacation
    12/20/2021 | Rest cycle / unmedicated TTC + Pregmune Immunology Testing; BFN
    01/22/2022 | Rest cycle / unmedicated TTC + understanding uncovered immunological issues; BFN
    02/18/2022 | Mock transfer cycle! ERA, ReceptivaDx, EMMA/ALICE; start Prednisone to address NK activity
    03/16/2022 | Final, "Hail Mary" super-ovulation + TI cycle before FET; BFP! EDD: 12/21/2022 | MMC 05/08/2022
    05/20/2022 | D&C; recovering... 
    06/21/2022 | Trying naturally until October 2022
    07/21/2022 | BFP! EDD 04/02/2023; 👦🏼 born on 4/5/2023


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    @acleverusername welcome! I am so sorry that you find yourself here, but you couldn't ask for a more helpful and supportive group of ladies. My primary care doctor referred me to my RE, so choosing was pretty easy. I teach elementary school. It's tough to find open teaching positions at that level where I live, though. :( 

    @inthewoods23 LOL at "breaking in the bed". And for a second I thought, "Oh nice, she got a new bed!" *facepalm* 

    @mvt2003 I am so glad that you feel at peace after your transfer. I completely agree with you about not testing until the morning of your beta. That's what I plan to do too.

    @shoogapoff we signed a form saying that we did NOT want to know the sex of our embryos along with the test results. We wanted something to be a surprise! Your consent forms for the PGS testing might have that option. 

    @misshelen86 YAY for finally starting treatment!! I am so excited for you and your DH!

    @legallykate hooray for growth and good numbers! 
    @gingermama29 I hope the next two weeks FLY by so you can wave goodbye to those BCPs!

    @bluetickgal I am so excited for you and your DH about getting started with the adoption process. Keep us updated! FX that switching your meds helps. 

    @avidlyuks36 welcome! I only have 1 IUI experience (our second one was cancelled because my ovaries decided to be jerks). It was all pretty simple, but obviously it didn't work for us that time. 

    @abarr723 congratulations on getting your RN! That is amazing! 

  • Options
    @acleverusername I did IUIs (5 of them previously before we decided to take a break from treatment and actively trying). I was on Letrozole for most of the IUI cycles, which I responded really well too once we found the right dose. My last IUI cycle I was on clomid, which I did not respond well too. I also did the ovidrel trigger.

    My RE won't do Gonal-F for me because of the increased risk of multiples that it has.
    TW** I had high blood pressure when I was pregnant with my son, and my RE wants to avoid from happening again as much as possible...having multiples would not be good! End TW***
    Our TTC Journey
    TTC #1: May 2011
    BFP: 10/27/2011 |  EDD: 6/30/12
    DS born 6/28/12 via C/S 3 

    TTC #2: September 2018
    Me: 36 | DH: 39
    Mirena removed 9/13/2018 after 6 years
    BFP 11/11/2018 | MC @ 5.5 weeks on Thanksgiving
    July 2019 - Diagnosed with Secondary Unexplained IF
    August 2019 - 2.5 mg of Letrozole = Never Ovulated so Trigger and IUI were cancelled
    9/30/2019 - IUI #1 (5 mg of Letrozole + Trigger) =  BFP but Betas showed CP @ 4 weeks
    10/28/2019 - IUI #2 (7.5mg of Letrozole + Trigger) = BFN
    11/25/2019 - IUI #3 (7.5mg of Letrozole, Trigger + Crinone after IUI) = BFN
    12/24/2019 - IUI #4 (7.5mg of Letrozole + Crinone after IUI) = BFN
    1/24/2020 - IUI #5 (50mg of Clomid + Trigger + Crinone after IUI) = BFN and an Ovarian Cyst
    3/2/2020 - Taking a break to reset/NTNP
    11/1/2020 - At peace with where things are in life and are no long actively TTC. Whatever happens will happen and it will all be okay. <3

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    @legallykate I got an itchy whelp from ganirelix too. That one is absolutely my least favorite so far. @bluetickgal @kpearse99 I agree with @mvt2003 that gonal-f is easier than the trigger. Side note,  one of the other clinical trials going on at my clinic is about pre-mixed menopur and whether or not it is as effective as the current method. That would be really nice! 
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    @acleverusername — thank you — good luck to you too!

    @abarr723 — that's amazing — I feel like doctors downplay how often women in their 40’s can get pregnant.

    bluetickgal — sorry about the post — I corrected it and will be more mindful of the rules in the future

    mvt2003 — thank you for the welcome

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    @emeraldduchess The box of IVF meds IS really intimidating. It helped for me to sort everything out. And as I have gone on, it's felt like the boxes have disappeared rather quickly, so I feel less overwhelmed by all of it. I'm so glad to hear that the job situation is looking good! FX for you! 
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    @keikilove I am SO ecstatic that you're moving forward!!! I agree, BCP was the DEVIL and I despised every minute of it. So, in terms of Egg Retrieval, this was how it worked at my clinic:

    I arrived early to my appointment, and was brought in back to change and have my IV placed. I hung out with MH and waited, was sent to the bathroom for one last pee, then walked to the OR. (This is when I started my freak out :D ). The table was very much like a transfer table, with full leg stirrups, I got on and they started my anesthesia drip - it's twilight anesthesia so not a full knock-out but you are still asleep. The whole procedure is very quick, it only takes about 15-20 minutes and you're in the recovery room before you know it. I woke up covered in warm blankets with a heating pack on my stomach already and discussed chicken fingers with my nurse. :D 
    me: 35 / so: 34 | ttc #1 since 9/2018
    DX: MFI
    IVF Cycle #1 February 2020 4 embryos frozen, 1 fresh transfer = CP 
    FET #1 Natural Cycle March 2020 CXL'd due to Covid-19 :( 
    FET #1 Natural Cycle June 2020 - CP #2
    FET #2 Natural Cycle July 2020 - BFP!!!!!! Beta #1 = 273


    June Signature Challenge - Favorite TV Quotes


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    @mvt2003 Thank you so much! Your description has put my mind at ease a little bit. Especially laughing at you discussing chicken fingers with your nurse!😄

    @shoogapoff I missed your update. Congrats on that great number of follies! Hoping right along with you that everything stays on track for a weekend retrieval!🤞🏽
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    @acleverusername thanks, that’s just what seems right for us! I think keeping one RE consult as a second opinion sounds like a good idea. No real insight on the thyroid issue and getting that in check before starting a medicated cycle, but that doesn’t sound like a bad idea if you think that could be done within a cycle or less. I have had minimal side-effects with Letrozole (some headaches & night sweats/hot flashes, but nothing too severe), so hopefully you have a good experience if that’s at you go with! Did your OB have any opinions on waiting or just going through with all the meds now? 
    @emeraldduchess thanks, friend! We are so excited too, and I’ll definitely keep you all updated! So sorry all the meds seems really overwhelming...you’ve got this though, just take it one injection at a time! That stinks about your squeamish incident with the blood draw, so glad the nurses were sweet about it though! Fingers crossed so hard that you get good news about the job this week!! 
    @shoogapoff awesome, so great to hear that the gonal-F should be a breeze! That is interesting about the Menopur clinical trial! That sounds like wonderful progress on follicles!! Fingers crossed so hard for an ER this weekend for you!! 
    @avidlyuks36 thank you, that is definitely appreciated! This is such a wonderful community, the rules/practices in place help protect each other and make this a safe space for everyone! Your follicle sizes sound good, hopefully they are the perfect size for trigger on Friday and IUI Saturday! 
    @keikilove thanks so much, friend!! Eek, I’m so excited you are moving forward with your IVF cycle very soon! So sorry that the BCP side-effects are so rough! Hope the next week goes by quickly for you!! That is wonderful that you found another back-up clinic and you can hopefully forget about the other one! Fingers crossed so hard that you won’t even need the backup though!! 
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    Before I deep-dive on google -- I was wondering how do you test out the trigger shot. I have a pack of cheap pregnancy tests (the little strips) and I was wondering what day do I start testing?
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    @avidlyuks36 You just start POAS starting the day after you do the trigger shot until the line is totally faded to blank (or fades and then starts getting darker again... which of course is wonderful news!)
    Our TTC Journey
    TTC #1: May 2011
    BFP: 10/27/2011 |  EDD: 6/30/12
    DS born 6/28/12 via C/S 3 

    TTC #2: September 2018
    Me: 36 | DH: 39
    Mirena removed 9/13/2018 after 6 years
    BFP 11/11/2018 | MC @ 5.5 weeks on Thanksgiving
    July 2019 - Diagnosed with Secondary Unexplained IF
    August 2019 - 2.5 mg of Letrozole = Never Ovulated so Trigger and IUI were cancelled
    9/30/2019 - IUI #1 (5 mg of Letrozole + Trigger) =  BFP but Betas showed CP @ 4 weeks
    10/28/2019 - IUI #2 (7.5mg of Letrozole + Trigger) = BFN
    11/25/2019 - IUI #3 (7.5mg of Letrozole, Trigger + Crinone after IUI) = BFN
    12/24/2019 - IUI #4 (7.5mg of Letrozole + Crinone after IUI) = BFN
    1/24/2020 - IUI #5 (50mg of Clomid + Trigger + Crinone after IUI) = BFN and an Ovarian Cyst
    3/2/2020 - Taking a break to reset/NTNP
    11/1/2020 - At peace with where things are in life and are no long actively TTC. Whatever happens will happen and it will all be okay. <3

  • Options
    edited July 2020
    @keikilove thanks for the welcome, description of what you'd gone through and the advice on what to do with all these meds and appointments! This is very helpful and I 100% feel/know that I have indeed found "the most supportive corner of TB."

    In terms of anesthesia, I've done egg retrieval for freezing before and there _is_ an alternative to general anesthesia, however I've never heard of anyone doing it in any of the forums I frequent... well, except for 1 other person. I'll add more details & my experience with it in spoiler.
    So, this alternative is called "oral conscious sedation". A research article about it: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5586085/. They basically inject fentanyl into your uterus/vaginal wall, so you don't feel the needle going in. So, I had this type of sedation and... well, it's not the most comfortable. But bear with me when I say this... it's actually kind of cool to be able to see the needle sucking up your eggs. (There was a monitor in the OR so I could see everything happening). And I also got to hear them call out as each egg was discovered. That said, they did have to give me 2 doses of fentanyl cause I started to get pretty uncomfortable after 10 minutes. Anyway, it's definitely not for the queasy stomach. If you're interested, I'd ask your RE about it. Like I said, I've only ever heard of one other person having had this kind of anesthesia.
    MY CHART
    TTC History
    TTC#2
    Me: 40.5; MH: 39 | Met 02/2009 | Started Dating 08/2017 | Married 02/02/2020
    TTC #2 ... preparing as of March 2024


    TTC #1
    Me: 36, MH: 34 | Met 02/2009 | Started Dating 08/2017 | Married 02/02/2020
    TTC #1 02/2020 - 07/2022
    2009 | Dx PCOS; likely a misdiagnosis
    07/14/20 | Dx Hashimoto's Thyroditis
    07/21/20 | 1st RE appointment
    07/2120 - 08/20/20 | so much testing; no signs of PCOS
    08/20/20 | Dx Unexplained; AMA
    09/08/20 | IUI #1 Clomid + Trigger + Prometrium | BFN
    09/30/20 | Urology consult; more testing required
    10/2020 | Clomid + OPK + TI + Prometrium | BFN
    10/26/2020 | Starting 2nd IUI cycle, with Letrazole and with a new RE / different clinic
    11/03/2020 | New Dx "poor egg quality"; IUI cancelled in favor of Trigger + TI + Prometrium | BFN
    11/26/2020 | Combo IUI (Clomid + Menopur) + Trigger + Prometrium | BFN
    12/20/2020 | Combo IUI (Clomid + Gonal-F) + Trigger | IUI Cancelled due to thin lining; TI only | BFN
    01/14/2021 | Combo IUI (Letrazole + Menopur) + Trigger | BFN
    02/06/2021 | Switched to a new RE (TEW) ; trying naturally until we complete additional testing 
    03/14/2021 | Hybrid Double IUI, with Zymot (Letrazole, Gonal-F) + Trigger + Endometrin | Ovulated 4 mature eggs but still a BFN ☹️
    04/07/2021 | Natural cycle while we regroup | BFN
    04/09/2021 | Employer announces fertility benefits starting 05/01/2021! | Search for a new doctor who accepts insurance
    05/10/2021 | New RE consult & plan for IVF
    05/13/2021 | Mid-luteal IVF cycle #1 interrupted; had to get cancer genetic screening done to make sure I didn't have the same SDHA gene mutation as MH. 
    06/10/2021 | Aygestin priming IVF cycle #1; opted to Cx after 9 days of stims since only 5-6/12 follicles responded
    07/26/2021 | Attempt #2 at IVF cycle #1 (mid-luteal start): 8 retrieved, 8 MII, 6 fert (1 PN3), 3 Day 5 & 6 blasts: 3AA, 3AA, 6AB; 3 euploid
    08/09/2021 | Rest cycle / unmedicated TTC | Shockingly, a BFP! EDD: 5/25/202 | CP at 4w4d
    09/23/2021 | IVF cycle #2 (mid-luteal start): 14 retrieved, 13 MII, 11 fert, 5 Day 5 & 6 blasts: 2 x 3AA, 2 x 3AB, 3BB; 2 euploid
    11/12/2021 | IVF cycle #3 (mid-luteal start): cancelled due to ovaries being on vacation
    12/20/2021 | Rest cycle / unmedicated TTC + Pregmune Immunology Testing; BFN
    01/22/2022 | Rest cycle / unmedicated TTC + understanding uncovered immunological issues; BFN
    02/18/2022 | Mock transfer cycle! ERA, ReceptivaDx, EMMA/ALICE; start Prednisone to address NK activity
    03/16/2022 | Final, "Hail Mary" super-ovulation + TI cycle before FET; BFP! EDD: 12/21/2022 | MMC 05/08/2022
    05/20/2022 | D&C; recovering... 
    06/21/2022 | Trying naturally until October 2022
    07/21/2022 | BFP! EDD 04/02/2023; 👦🏼 born on 4/5/2023


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    @emeraldduchess what's that?? no nonsense?
    John Krasinski Rainn Wilson GIF  Gfycat
    *TW* History:
    Me: 34 DH: 36 | Together since 2007 | Married July 2016

    TTC #1 since 7.2017
    Dx: low morph (1%), ANA positive, low decidualization score, high TSH and testosterone, histone antibodies

    IUI #1-3 all BFN
    IVF #1 | 6.11.19 | 24R, 17M, 15F, 6B, PGT-A tested - 5 normal, 3 girls & 2 boys
    FET #1 | 9.10.19 | BFN "I know you, but we've never met. I'm with you, but I don't know your name"
    RPL, Receptiva, & ERA testing | all normal/negative, recommended going on gluten and dairy free diet for next FET
    FET #2 | 3.31.20 | Opted to cancelled due to pandemic, continued diet and tried naturally over the summer
    2nd Opinion with another RE | 8.20.20 | Not immune to measles (received 1 dose); SA results similar to 2 years ago; decided to move forward with FET #2 redo at start of next cycle
    Surprise natural BFP! | 9.22.20 | MC 10.23.20 at 8 weeks
    TTCAL naturally | starting 11.22.20

    Initial consultation with Reproductive Immunologist | 9.14.21
    Decidualization score biopsy | 10.1.21 | abnormal - low score of 1; endometrial scratch recommended and progesterone supplementation
    Saline sono | 10.15.21 | normal
    Bloodwork | 10.21.21 high TSH, high testosterone, positive for anti-nuclear antibodies and histone antibodies, high protein S, multiple genetic mutations
    BFP! | 11.3.21 | EDD 7.14.22 B) | biopsy provided same effect as endometrial scratch; added supplemental progesterone and estrogen, prednisone, levothyroxine, and MTX Support to maintain pregnancy
    DS born 7.19.22 after induction


    TTC #2 begins 6.2023
    Consultation with RI | 6.6.23
    Saline sono, endometritis biopsy, skin & eye check | all normal
    Labs | high TSH, Factor XIII mutation, high %CD56
    Follow up | 8.8.23 | prescribed metformin, prednisone, plaquenil, and levothyroxine
    Repeat labs after 3 weeks on meds
    Follow up | 11.9.23 | Green light!, increase in prednisone, added lovenox
    Repeat labs in 8 weeks
    Follow up | 1.16.24 | Green light continues
    TTC put on pause
  • Options
    @kiki047 - thank you for the warm welcome and you're right we do have a lot in common!!! Here's one more thing: I'm from Canada, although I moved to the US 2 years ago; needed a break from Canada winters. During my convo with the OB yesterday, she did explain that she didn't think DH is the issue here; she said anything below 40mil/ml would worth doing something about; however, on the motility side of things, she said she likes to see things 60% or higher. MH's sperm is about as motile as he is 🤣. That said, I have convinced him to take a supplements, and even ubiquinol and those 2 things should improve his situation. Oh, and I'm also doing acupuncture, even if it's voodoo. It's relaxing and it could only be a good thing. 

    I am sorry the first FET was so traumatic. Such bad timing. But it sounds like this time everything is lining up much more nicely. FX for you. 



    MY CHART
    TTC History
    TTC#2
    Me: 40.5; MH: 39 | Met 02/2009 | Started Dating 08/2017 | Married 02/02/2020
    TTC #2 ... preparing as of March 2024


    TTC #1
    Me: 36, MH: 34 | Met 02/2009 | Started Dating 08/2017 | Married 02/02/2020
    TTC #1 02/2020 - 07/2022
    2009 | Dx PCOS; likely a misdiagnosis
    07/14/20 | Dx Hashimoto's Thyroditis
    07/21/20 | 1st RE appointment
    07/2120 - 08/20/20 | so much testing; no signs of PCOS
    08/20/20 | Dx Unexplained; AMA
    09/08/20 | IUI #1 Clomid + Trigger + Prometrium | BFN
    09/30/20 | Urology consult; more testing required
    10/2020 | Clomid + OPK + TI + Prometrium | BFN
    10/26/2020 | Starting 2nd IUI cycle, with Letrazole and with a new RE / different clinic
    11/03/2020 | New Dx "poor egg quality"; IUI cancelled in favor of Trigger + TI + Prometrium | BFN
    11/26/2020 | Combo IUI (Clomid + Menopur) + Trigger + Prometrium | BFN
    12/20/2020 | Combo IUI (Clomid + Gonal-F) + Trigger | IUI Cancelled due to thin lining; TI only | BFN
    01/14/2021 | Combo IUI (Letrazole + Menopur) + Trigger | BFN
    02/06/2021 | Switched to a new RE (TEW) ; trying naturally until we complete additional testing 
    03/14/2021 | Hybrid Double IUI, with Zymot (Letrazole, Gonal-F) + Trigger + Endometrin | Ovulated 4 mature eggs but still a BFN ☹️
    04/07/2021 | Natural cycle while we regroup | BFN
    04/09/2021 | Employer announces fertility benefits starting 05/01/2021! | Search for a new doctor who accepts insurance
    05/10/2021 | New RE consult & plan for IVF
    05/13/2021 | Mid-luteal IVF cycle #1 interrupted; had to get cancer genetic screening done to make sure I didn't have the same SDHA gene mutation as MH. 
    06/10/2021 | Aygestin priming IVF cycle #1; opted to Cx after 9 days of stims since only 5-6/12 follicles responded
    07/26/2021 | Attempt #2 at IVF cycle #1 (mid-luteal start): 8 retrieved, 8 MII, 6 fert (1 PN3), 3 Day 5 & 6 blasts: 3AA, 3AA, 6AB; 3 euploid
    08/09/2021 | Rest cycle / unmedicated TTC | Shockingly, a BFP! EDD: 5/25/202 | CP at 4w4d
    09/23/2021 | IVF cycle #2 (mid-luteal start): 14 retrieved, 13 MII, 11 fert, 5 Day 5 & 6 blasts: 2 x 3AA, 2 x 3AB, 3BB; 2 euploid
    11/12/2021 | IVF cycle #3 (mid-luteal start): cancelled due to ovaries being on vacation
    12/20/2021 | Rest cycle / unmedicated TTC + Pregmune Immunology Testing; BFN
    01/22/2022 | Rest cycle / unmedicated TTC + understanding uncovered immunological issues; BFN
    02/18/2022 | Mock transfer cycle! ERA, ReceptivaDx, EMMA/ALICE; start Prednisone to address NK activity
    03/16/2022 | Final, "Hail Mary" super-ovulation + TI cycle before FET; BFP! EDD: 12/21/2022 | MMC 05/08/2022
    05/20/2022 | D&C; recovering... 
    06/21/2022 | Trying naturally until October 2022
    07/21/2022 | BFP! EDD 04/02/2023; 👦🏼 born on 4/5/2023


  • Options
    @emeraldduchess does this mean you're almost ready for your estrogen priming to start?! That's so exciting!

    @legallykate how many follies on each ovary? You had 11 at last check-in, where they mostly on the right? When I did ER for freezing, my left ovary only produced 4 follicles; whereas my right was on fire with 10. I called my ovary "social loafer". Either way, hopefully more will grow between now and Friday/Saturday so that you get a good crop on Sunday. 


    MY CHART
    TTC History
    TTC#2
    Me: 40.5; MH: 39 | Met 02/2009 | Started Dating 08/2017 | Married 02/02/2020
    TTC #2 ... preparing as of March 2024


    TTC #1
    Me: 36, MH: 34 | Met 02/2009 | Started Dating 08/2017 | Married 02/02/2020
    TTC #1 02/2020 - 07/2022
    2009 | Dx PCOS; likely a misdiagnosis
    07/14/20 | Dx Hashimoto's Thyroditis
    07/21/20 | 1st RE appointment
    07/2120 - 08/20/20 | so much testing; no signs of PCOS
    08/20/20 | Dx Unexplained; AMA
    09/08/20 | IUI #1 Clomid + Trigger + Prometrium | BFN
    09/30/20 | Urology consult; more testing required
    10/2020 | Clomid + OPK + TI + Prometrium | BFN
    10/26/2020 | Starting 2nd IUI cycle, with Letrazole and with a new RE / different clinic
    11/03/2020 | New Dx "poor egg quality"; IUI cancelled in favor of Trigger + TI + Prometrium | BFN
    11/26/2020 | Combo IUI (Clomid + Menopur) + Trigger + Prometrium | BFN
    12/20/2020 | Combo IUI (Clomid + Gonal-F) + Trigger | IUI Cancelled due to thin lining; TI only | BFN
    01/14/2021 | Combo IUI (Letrazole + Menopur) + Trigger | BFN
    02/06/2021 | Switched to a new RE (TEW) ; trying naturally until we complete additional testing 
    03/14/2021 | Hybrid Double IUI, with Zymot (Letrazole, Gonal-F) + Trigger + Endometrin | Ovulated 4 mature eggs but still a BFN ☹️
    04/07/2021 | Natural cycle while we regroup | BFN
    04/09/2021 | Employer announces fertility benefits starting 05/01/2021! | Search for a new doctor who accepts insurance
    05/10/2021 | New RE consult & plan for IVF
    05/13/2021 | Mid-luteal IVF cycle #1 interrupted; had to get cancer genetic screening done to make sure I didn't have the same SDHA gene mutation as MH. 
    06/10/2021 | Aygestin priming IVF cycle #1; opted to Cx after 9 days of stims since only 5-6/12 follicles responded
    07/26/2021 | Attempt #2 at IVF cycle #1 (mid-luteal start): 8 retrieved, 8 MII, 6 fert (1 PN3), 3 Day 5 & 6 blasts: 3AA, 3AA, 6AB; 3 euploid
    08/09/2021 | Rest cycle / unmedicated TTC | Shockingly, a BFP! EDD: 5/25/202 | CP at 4w4d
    09/23/2021 | IVF cycle #2 (mid-luteal start): 14 retrieved, 13 MII, 11 fert, 5 Day 5 & 6 blasts: 2 x 3AA, 2 x 3AB, 3BB; 2 euploid
    11/12/2021 | IVF cycle #3 (mid-luteal start): cancelled due to ovaries being on vacation
    12/20/2021 | Rest cycle / unmedicated TTC + Pregmune Immunology Testing; BFN
    01/22/2022 | Rest cycle / unmedicated TTC + understanding uncovered immunological issues; BFN
    02/18/2022 | Mock transfer cycle! ERA, ReceptivaDx, EMMA/ALICE; start Prednisone to address NK activity
    03/16/2022 | Final, "Hail Mary" super-ovulation + TI cycle before FET; BFP! EDD: 12/21/2022 | MMC 05/08/2022
    05/20/2022 | D&C; recovering... 
    06/21/2022 | Trying naturally until October 2022
    07/21/2022 | BFP! EDD 04/02/2023; 👦🏼 born on 4/5/2023


  • Options
    @acleverusername I think so! As soon as I surge, I put the patch on and wear it until AF shows up. I responded really well to Letrozole the 4 cycles that I was on it, so even though my last AMH was really low, I am hoping that I respond really well to the IVF meds. As tough as it was to put everything on hold due to COVID, I'm actually glad now that I'll be doing meds before school starts again (assuming we'll be in the school and not doing remote learning). That way if I have any really unpleasant side effects I'll be able to deal with them at home. 
  • Options
    legallykatelegallykate member
    edited July 2020
    @acleverusername He said I still just had 11 measurable follies, 7 on the right (4 15-16s, 2 12-13s, and one smaller one) and 4 on the left but all 11 or smaller. So he thinks the 15/16s will be good for retrieval by Sunday or early next week and also hopefully the 12/13s and maybe the 11 from the left. It's so confusing, the measurements seem so imprecise to me and he said he was having trouble measuring them yesterday because my bladder seemed fuller. So just going to hope for some last minute growth/additions!
    *TTC History*

    Me: 37, MH: 38; Married August 2017

    TTC #1 October 2017: BFP on 12/1/2017, DD born 7/24/2018 @ 37+1 after induction due to preeclampsia

    TTC #2 January 2020: AMA, dx with DOR in May 2020

    IVF July 2020: 16 eggs retrieved, 14 mature, 12 fertilized, 3 blasts, 2 PGT-A normal

    FET 10/7/20: BFP on 10/12/20!!! (EDD 6/25/21); First beta 10/16/20 (9dpt): 148; Second beta 10/19/20 (12dpt): 621; Third beta 10/26/20 (19dpt): 4732; Fourth (and final!) beta 11/2/20 (26 dpt): 22,000+

  • Options
    @mvt2003 oh boy!!! At least Lloyd and Harry are fashionable!
    Our TTC Journey
    TTC #1: May 2011
    BFP: 10/27/2011 |  EDD: 6/30/12
    DS born 6/28/12 via C/S 3 

    TTC #2: September 2018
    Me: 36 | DH: 39
    Mirena removed 9/13/2018 after 6 years
    BFP 11/11/2018 | MC @ 5.5 weeks on Thanksgiving
    July 2019 - Diagnosed with Secondary Unexplained IF
    August 2019 - 2.5 mg of Letrozole = Never Ovulated so Trigger and IUI were cancelled
    9/30/2019 - IUI #1 (5 mg of Letrozole + Trigger) =  BFP but Betas showed CP @ 4 weeks
    10/28/2019 - IUI #2 (7.5mg of Letrozole + Trigger) = BFN
    11/25/2019 - IUI #3 (7.5mg of Letrozole, Trigger + Crinone after IUI) = BFN
    12/24/2019 - IUI #4 (7.5mg of Letrozole + Crinone after IUI) = BFN
    1/24/2020 - IUI #5 (50mg of Clomid + Trigger + Crinone after IUI) = BFN and an Ovarian Cyst
    3/2/2020 - Taking a break to reset/NTNP
    11/1/2020 - At peace with where things are in life and are no long actively TTC. Whatever happens will happen and it will all be okay. <3

  • Options
    @mvt2003 I almost prefer it that MH doesn't do any independent research/know much beyond what I tell him, he can be an overthinker (not unlike me), I think the two of us overthinking and obsessing would be way too much! 
    *TTC History*

    Me: 37, MH: 38; Married August 2017

    TTC #1 October 2017: BFP on 12/1/2017, DD born 7/24/2018 @ 37+1 after induction due to preeclampsia

    TTC #2 January 2020: AMA, dx with DOR in May 2020

    IVF July 2020: 16 eggs retrieved, 14 mature, 12 fertilized, 3 blasts, 2 PGT-A normal

    FET 10/7/20: BFP on 10/12/20!!! (EDD 6/25/21); First beta 10/16/20 (9dpt): 148; Second beta 10/19/20 (12dpt): 621; Third beta 10/26/20 (19dpt): 4732; Fourth (and final!) beta 11/2/20 (26 dpt): 22,000+

  • Options
    @mvt2003 that is truly hilarious; but it's good that YH has a support system. Guys often don't take the time to get one going and I can only imagine how isolating this experience can be for them. I can visualize your reaction though; that would have been me too. 🤣
    MY CHART
    TTC History
    TTC#2
    Me: 40.5; MH: 39 | Met 02/2009 | Started Dating 08/2017 | Married 02/02/2020
    TTC #2 ... preparing as of March 2024


    TTC #1
    Me: 36, MH: 34 | Met 02/2009 | Started Dating 08/2017 | Married 02/02/2020
    TTC #1 02/2020 - 07/2022
    2009 | Dx PCOS; likely a misdiagnosis
    07/14/20 | Dx Hashimoto's Thyroditis
    07/21/20 | 1st RE appointment
    07/2120 - 08/20/20 | so much testing; no signs of PCOS
    08/20/20 | Dx Unexplained; AMA
    09/08/20 | IUI #1 Clomid + Trigger + Prometrium | BFN
    09/30/20 | Urology consult; more testing required
    10/2020 | Clomid + OPK + TI + Prometrium | BFN
    10/26/2020 | Starting 2nd IUI cycle, with Letrazole and with a new RE / different clinic
    11/03/2020 | New Dx "poor egg quality"; IUI cancelled in favor of Trigger + TI + Prometrium | BFN
    11/26/2020 | Combo IUI (Clomid + Menopur) + Trigger + Prometrium | BFN
    12/20/2020 | Combo IUI (Clomid + Gonal-F) + Trigger | IUI Cancelled due to thin lining; TI only | BFN
    01/14/2021 | Combo IUI (Letrazole + Menopur) + Trigger | BFN
    02/06/2021 | Switched to a new RE (TEW) ; trying naturally until we complete additional testing 
    03/14/2021 | Hybrid Double IUI, with Zymot (Letrazole, Gonal-F) + Trigger + Endometrin | Ovulated 4 mature eggs but still a BFN ☹️
    04/07/2021 | Natural cycle while we regroup | BFN
    04/09/2021 | Employer announces fertility benefits starting 05/01/2021! | Search for a new doctor who accepts insurance
    05/10/2021 | New RE consult & plan for IVF
    05/13/2021 | Mid-luteal IVF cycle #1 interrupted; had to get cancer genetic screening done to make sure I didn't have the same SDHA gene mutation as MH. 
    06/10/2021 | Aygestin priming IVF cycle #1; opted to Cx after 9 days of stims since only 5-6/12 follicles responded
    07/26/2021 | Attempt #2 at IVF cycle #1 (mid-luteal start): 8 retrieved, 8 MII, 6 fert (1 PN3), 3 Day 5 & 6 blasts: 3AA, 3AA, 6AB; 3 euploid
    08/09/2021 | Rest cycle / unmedicated TTC | Shockingly, a BFP! EDD: 5/25/202 | CP at 4w4d
    09/23/2021 | IVF cycle #2 (mid-luteal start): 14 retrieved, 13 MII, 11 fert, 5 Day 5 & 6 blasts: 2 x 3AA, 2 x 3AB, 3BB; 2 euploid
    11/12/2021 | IVF cycle #3 (mid-luteal start): cancelled due to ovaries being on vacation
    12/20/2021 | Rest cycle / unmedicated TTC + Pregmune Immunology Testing; BFN
    01/22/2022 | Rest cycle / unmedicated TTC + understanding uncovered immunological issues; BFN
    02/18/2022 | Mock transfer cycle! ERA, ReceptivaDx, EMMA/ALICE; start Prednisone to address NK activity
    03/16/2022 | Final, "Hail Mary" super-ovulation + TI cycle before FET; BFP! EDD: 12/21/2022 | MMC 05/08/2022
    05/20/2022 | D&C; recovering... 
    06/21/2022 | Trying naturally until October 2022
    07/21/2022 | BFP! EDD 04/02/2023; 👦🏼 born on 4/5/2023


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