Thanks everyone for your input on PGS testing. DH and I decided we are going to go ahead with it (unless we only have 1 or 2 embryos of course). So for us this means frozen transfer.
How is everyone doing with stims? I honestly have not noticed a ton of symptoms but am only on my third day. My stomach looks like a pin cushion though!
Me 32, DH 34
TTC #1 since December 2014
Unexplained infertility/borderline low AMH
February 2016: IUI #1 (50 mg clomid + ovidrel) -- BFN
March 2016: IUI #2 (2.5 mg Letrozole + ovidrel) -- BFN
May 2016: IUI #3 (5 mg Letrozole + ovidrel + prometrium) -- BFN
August 2016: IVF #1 (Lupron, Gonal F and Menopur) -- 12 retrieved, 9 fertilized, 3 frozen and 1 x day 5 hatching blast transferred -- BFN. Sent remaining 3 embryos for PGS testing -- 2 didn't survive thaw, 1 was abnormal.
February 2017: IVF #2 (Gonal F, Menopur, and Ganirelix) -- 12 retrieved, 6 fertilized, 3 sent for PGS testing and all were abnormal
February 2018: planning for IVF #3
@omarismyhomeboy- Congrats on the great follicle count! best news you can get from the first check up! When do you go back again? Did they make any adjustments to your meds?
@teamginger13- Glad you aren't having too many side effects! I definitely felt something going on after I started on Sat.. and just feel a little achy down there. Tonight is night 3, so I am assuming it will get more symptoms each night.
I have been on the fence about PGS testing too... but my RE did not reco it since I'm 28... but I still you ladies are also either 30 or 31. I think I'm going to have another conversation about it with her.. and also see how many eggs we end up getting and then decide.
@Colleen0516- That is hard with the bachelor party. I totally hear you, I am a planner too but the timing with this is just so hard since we have no control over it! How was your follie count? Hoping you got good news and that longer stimming gives you the results you need!
I had my first check up this morning.. and honestly feeling really disappointed and deflated. My right (bum) ovary had no follicles, but that really wasn't necessarily unexpected. My left had 10 (same as baseline) and some were starting to grow (I have only stimmed for 3 nights now). I realize it could be much worse, but just feel like with the highest potential of getting 10 eggs (if we are lucky), my odds of getting 1-2 to day 5 just aren't great. I was so hopeful, but now I am just feeling scared. Sorry to be a downer... its just such a rollercoaster and feeling so low right now. Going to try to get through work and then hopefully the nurse will call soon with updated instructions.
Hang in there @jamieh2000! 10 is still a good number and remember you only need 1 to make a baby I know how stressful it is though. I keep thinking to myself how awful it would be to go thru all of this emotional, physical, financial pain to just be left with nothing. Hang in there and FX for you!
How did your follie count go @colleen0516?
I go today for bloodwork and my first u/s isn't until Thursday. I am dying to know how my follies are growing.. especially because I haven't been feeling many symptoms. In my crazy mind I feel like no symptoms = nothing is happening but I know that is probably not true.
@teamginger13- thanks for the encouragement. I really need it. The nurse called, and I asked how many follies they had measured and it was only 7 (11mm, 8mm, and then 5 less then 8mm). I know its early, and they are upping my meds from 350 to 400 of follistim and adding low dose HCG, but I am terrified I may not make it to ER (they want at least 3-4 mature) and if I do, I may only get a couple eggs. Its just so hard because there is literally nothing I can do about this to change it. I have been going to acupuncture for 2 months, eating healthy, taking all the supplements and the reality is I just have one productive ovary.
I really hope everyone else is getting better news! Looking forward to hearing all the updates!
@srh18- wow, amazing numbers!! I'm sure its getting uncomfortable but you are so lucky to have so many! I'm sure your RE will be watching you closely for OHSS.
@Colleen0516- thank you so much, I really needed that. I think I was so upset since I assumed I would be having 10 follies growing and then they only counted 7. I am just praying that more keep growing. They did mention if I don't get 4 mature follies, then they cancel so that was really scary. I just don't understand because I did only 150 of follistim for my IUI and got 4 mature follies and another 4 in the teens and we almost had to cancel the IUI. So I just don't understand how I only have 7 growing with 350 of meds!! Hoping I'm just a little slow to respond since my first apt was only 60 hours after I started stims. It sounds like you are having some good development with 16 follies and 7 about 10!! I really hope the sono isn't too bad. Its def not fun, but mine was pretty quick. Keep us updated on how its all going!
Ladies- you are so right. It is too early to worry. But I think I just had too high of expectations going into the first one, based on how I responded during my IUI injectibles. I really hope I am just a slow responder and more are coming. I hear you about not wanting too many if they aren't as good of quality, so just trying to stay positive that even if I only get a few, they will be good. After doing acupuncture, taking all the reco supplements and even eating a fertility friendly diet, there is literally nothing more I can do at this point so I just have to have faith in my RE. Obviously I want the first time to work, but if I need to do this again, maybe they will come up with an even better protocol.
@colleen0516- if I may ask, what dosage/meds are you on? I feel like I am already on the high end at 400, so hopefully that doesn't make them any less quality. I am on low dose HCG and dexamethasone to help with quality (at least according to the nurse). I totally get we are all different, but I find it so interesting how different REs do it different. I am so happy this cycle seems to be going exactly as your RE wanted it and I REALLY hope this is the one for you!! It looks like you may be the first in our group for ER!!
Ladies, unfortunately today has been not good for me. My U/S this morning showed 2 dominant follies and the 5 others were still below 7mm. The RE is calling later, but I am pretty sure I am about to get cancelled and converted to an IUI. I am absolutely devastated and couldn't even go into work. Does anyone know of any successes or others who have over come dominant follicles? I never really thought this would happen to me and trying to not lose all hope of ever having my own child Sorry to be the Debbie downer of the board.
Hope everyone else is getting much better news!
@JamieH2000 I am soooo sorry. I also had a terrible u/s this morning so I know how you are feeling. We can both be Debbie Downers today
AFM, my u/s this morning showed only 3 small follies on my left and 2 on my right. I expected to have way more than that. I mean 5 seems like not enough to do an ER, right? My doctor is supposed to call me later to tell me the next steps but I am trying to prepare myself. I feel so emotionally exhausted right now and just can't believe this is happening.
@teamginger- I am so sorry. My RE will do an ER for 3 eggs (just not 2), so hopefully they can just get all 5 to grow together and still do it! You are young at 31, so hopefully if you got 5 eggs at least 4 or more would be good ones! How many days have you been stimming? Hopefully they can up your meds and get those follies to grow!
AFM- the RE nurse just called and they want to give it two more days. I'm not holding out hope, since the 2 follies are so far ahead of the other 5... but at least they are trying everything they can. If the smaller ones don't start growing, then we will convert to an IUI. I was feeling hopeless this morning, but talked with my old RE office and confirmed that I had 5 mature follies in May and 3 that were almost mature (with much less meds) when I did my IUI. So thinking if this time doesn't work, I will definitely try again with different protocol since I have gotten 5-8 follies before. This is honestly just the most stressful journey and I can only pray eventually I will get a happy ending.
@Colleen0516- thanks for the support. I haven't talked to the RE yet, but if this cycle doesn't work (either IUI or IVF), then I am definitely going to be asking a lot of questions, especially how to avoid lead follicles like this. Still praying something works out and trying to stay positive. My nurse did say she had two ladies get pregnant in the last year when they were converted to an IUI, so it can happen. I was just really hoping to do the IVF with ICSI because I wonder how much DH's lower than normal morphology has been contributing to our challenges since I have always ovulated while we have been trying.
@omarismyhomeboy- thank you! Glad you are getting good scans and can't wait to hear how the ER goes. best wishes!