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Prometrium?

LizzieJ13LizzieJ13 member
in Infertility
I went in today (CD 11) for an ultrasound after my 3rd round of Letrozole. The nurse prescribed Prometrium starting this Sunday (CD 15). I'm not sure why she would prescribe it as it doesn't seem like I have any issues with my luteal phase, although I do have a blood test to check my progesterone next Friday. I just feel a little confused.

It was a tough appointment as (I might be reading too much into this) I got the impression that the nurse wasn't overly optimistic about my chances with Letrozole and was moving toward more tests/other treatment options... As I've mentioned before we won't be pursuing IUI or IVF so I'm a little nervous....
Me: 33, PCOS with anovulation
DH: 36, No known issues
TTC since 11/2014
1000mg Metformin daily

Oct-Dec 2015: Letrozole 5mg, Ovidrel, TI = BFN x 2
Feb-May 2016: Letrozole 5mg, Ovidrel, TI, Prometrium = BFN x 3
August 2016: Clomid 100mg no response, Letrozole 5mg, Ovidrel, TI, Prometrium = BFN

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Re: Prometrium?

  • KidShrinkKidShrink member
    I think she may actually be wanting to give you the best chances possible with your current treatment, especially if you're not going to be pursuing IUI or IVF. I had some spotting for my first cycle with letrozole, and so I was prescribed prometrium for every cycle after that, just to be safe. It's pretty common for people to be prescribed Prometrium too. 
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  • bbkidzbbkidz member
    I agree; I think she is trying to give you the best chances possible! I called my RE and asked for a progesterone supplement after first IUI, and he wouldn't prescribe it, but that IUI failed. This cycle, he is already planning to prescribe one. I would be thankful for it!
    Me:  29  DH:  32
    Together since January 23, 2013
    Married March 22, 2014
    TTC #1 since August 2015
    First RE meeting February 2, 2016; tests normal for both of us
    Clomid round #4 of 150 mg followed by
    First Ovidrel trigger shot February 10, 2016
    First IUI February 12, 2016 Negative
    Started Letrozole 5mg round #1 February 23
    Began additional Letrozole 5mg + Dexamethasone 1 mg March 8
    Ovidrel trigger shot March 16
    IUI #2 March 18 with progesterone suppositories beginning March 19
    Positive HPT April 2 Praise God!!! :)
    Estimated Due Date: December 8

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    Faith is the confidence that what we hope for will actually happen; it gives us assurance about things we cannot see. Hebrews 11:1
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  • srh18srh18 member
    I take prometrium for my TWW each cycle, with timed intercourse. My RE said it's just an extra boost/precaution, since my numbers have always been fine too. :)  
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  • LizzieJ13LizzieJ13 member
    edited February 2016
    Ok, thanks everyone :) This morning's visit to the RE was really overwhelming, and I guess I didn't ask all the questions I should have. I feel like for the first time this cycle the mood is less optimistic which really upset me. But hopefully the promethium helps!

    ETA: My period always comes 14 days after I ovulate (medicated) or get ovulation symptoms (unmedicated) so I'm thinking this is just a precaution -- if I had LP problems wouldn't I AF start earlier, or wouldn't I spot earlier?
    Me: 33, PCOS with anovulation
    DH: 36, No known issues
    TTC since 11/2014
    1000mg Metformin daily

    Oct-Dec 2015: Letrozole 5mg, Ovidrel, TI = BFN x 2
    Feb-May 2016: Letrozole 5mg, Ovidrel, TI, Prometrium = BFN x 3
    August 2016: Clomid 100mg no response, Letrozole 5mg, Ovidrel, TI, Prometrium = BFN

    Report Reply
  • twomommiestobetwomommiestobe member
    A lot of REs put you on progesterone to help support a pregnancy if you get a bfp. I would take them! :smile: if you get a bfp, you continue the progesterone for most of the first trimester. 

    RE DX for me: Anovulatory cycles/Mild PCOS  RE DX for DW: Endometrioma on left Ovary.
    Reciprocal Ivf Feb 2016. DW eggs and I am carrying. EDD: 10/27/16

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  • mtpbadgermtpbadger member
    My RE's office puts everyone on progesterone as standard. I've been on it for each of my previous 3 IUI's, starting the day after and will be on it during my first IVF cycle as well.
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