CCS/PGD ladies - Did you have to do all the same testing?

pblge

We have our first Ob/Gyn appt next week (assuming all is well at tomorrow's u/s) and I'd love some input for what other Ob/Gyns say on this topic. We did chromosomal screening on this embryo, so we're as certain as we can be that it doesn't have Down's or any other aneuploidy. We've also been screened for every genetic disorder known to man, it seems, so we know there's no Tay Sachs or CF, or etc. Obviously there are many more things that could go wrong with this pregnancy, but I'm wondering if this gives us a free pass on any of the usual screenings.

Any experiences? I am AMA (almost 37).

PS. I was going to post this on SAIF, but I peeked over there and it looks like mostly the same people. I'm realizing I don't know the difference between the boards. I guess I thought that one was for PAIF women who'd had their babies, but maybe I'm wrong?

SKLH

I also did CGH Testing and all the karotyping before our successful cycle. I've seen this topic a lot on this forum so you may want to search for it if you don't get a lot of responses but I was under the impression that some OB's still like for you to do the testing since the CGH results still have 1-2% room for error. My OB on the other hand, said there was really no reason to do the additional testing unless I really wanted to. I declined all of the testing and only opted for the nueral tube defects blood test (AFP) as those cannot be detected through genetic testing of the embryo. We had our anatomy scan last week and baby is perfect in every way (spine, kidneys, bladder, heart, brain measurments, fingers and toes!) so I'm a true believer in the genetic testing being sufficient! Good luck on your decision!

pblge

Oops! "> "> "> I totally should have searched first, sorry. It doesn't sound like there's really a consensus around this. Seems like a lot of REs and Ob/Gyns still recommend everything, while others think some of it is unnecessary. Here are all the threads I found in my quick search.

https://forums.thebump.com/discussion/comment/82069238#Comment_82069238

https://forums.thebump.com/discussion/comment/81081720#Comment_81081720

https://forums.thebump.com/discussion/comment/78841086#Comment_78841086

https://forums.thebump.com/discussion/12179609/did-you-do-the-nt-prenatal-screening

https://forums.thebump.com/discussion/comment/75336390#Comment_75336390

mdiblasi10

My OB gave us the choice, but actually felt our PGS was more accurate than some of the blood tests, and would hate to have a false positive or something like that freak us out. I opted out of the first tri b/w and just did the NT scan. I was going to do the second tri b/w, but decided not to at the last minute. Again, it was ultimately up to me. 

Good luck with your decision.

freakyfast

We did the PGD/CCS testing as well, and when it came time for the genetic testing with the ob, she gave us the pros and cons, but did say that the PGD testing is much better than say Maternit21 (or whatever that is called), she said because they actually test the embryo cells and not just the blood through the mom. She did tell us that since insurance didn't cover much of it, that she was not worried and we should use that money on a nice stroller.  

We did do all the of the other blood work and NT scan.  If anything had looked concerning on the NT scan we would have opted into the MaterniT21 testing, but everything looked and measured good.  

I know it is stressful, because I couldn't stop thinking about it for a few weeks, but when we opted out, our OB was 100% fine and agreed with our decision.  

Good luck! 

ksgsmu

I did pgd testing and I am pregnant with twins....  I see an MFM due to the twin pregnancy so I get ultrasounds every 3-4 weeks.  Both my MFM and OB said there was no reason to do additional testing unless something showed up on one of the ultrasounds.  Those tests with twins give a lot of false positives and we didn't want that stress either.