Infertility

Starting to explore IVF with ICSI

Hi--I am new to The Bump discussions, though unfortunately we have been facing infertility challenges for a while now. After extensive testing, we found out yesterday that hubby and I both have issues preventing us from conceiving--me: very low egg reserve even though I'm only 30 and hubby: low sperm numbers/poor motility. We are devastated. The doc said we have a 5% chance of conceiving or less on our own and said our only option is IVF with ICSI. I am overwhelmed. For those who have gone through an IVF cycle, what was it like? What can I expect? Any tips? How do you stay sane? I feel like one minute I'm sobbing and the next I'm angry we're in this situation. Has anyone done ICSI? The doc said ICSI can raise the risk of birth defects which really scares us.
TTC: August 2013
Me: Age 30/Diagnosis: low ovarian reserve
DH: Age 30/Diagnosis: low sperm count/quality

IVF #1: August 2014=BFN

Re: Starting to explore IVF with ICSI

  • Sorry you have to join us but Welcome.

    What to expect?

    Weight gain/bloating
    possible mood swings (for me, it wasn't actually too bad)
    Have to drop everything at the drop of a hat to go to a monitoring appt
    but with any luck at all, you will get a cute baby at the end, so focus on that.

    I did not to ICSI so can't help you there. Sorry
    ===siggy warning====
    Me: 40, DH: 42
    Diagnosis: PCOS
    TTC: May 2013
    TX: IUI #1 with Follistim. Canceled due to too many follicles (10 + that were large); BENCHED
    IVF #1 March 6. 14 eggs retrieved, 10 fertilized. 
    March 11, 4 eggs transferred.
    March 21 BFP  :) Beta #1 457, Beta #2 1350, Beta #3 9619. 
    Due Date November 27, 2014
    TEAM BLUE

  • jlr96jlr96 member

    Sorry you find yourself here but welcome to our wonderful group!  DH & I have the same issues you & your hubby have.  I was diagnosed with low ovarian reserve & he has low count/poor motility.  We just completed IVF w/ICSI.  I have also heard that ICSI increases your chances of birth defects-by about 2% I think it is-- but my RE did not seem worried about this.  I think ICSI is the only way we would have had any fertilized eggs & we were willing to take the chance.  I  had 4 mature eggs retrieved & all 4 were fertilized with ICSI. 

    IVF can be scary but you have found the right place for help, support & a vast amount of knowledge.  I learned so much from this group & it made my cycle so much easier to be able to talk to others going through the same thing.  Once you get your schedule, you can sign up for the monthly group with other ladies doing retrieval/transfer at the same time as you.  Get ready for lots of monitoring appointments & basically living your life around injections & blood draws.  Take it one day at a time.  The injects are overwhelming at first but you will get used to it & hopefully it will all be worth it in the end.  Best of luck to you!

    Me (36) - LOR, DH (34) - MFI (low count & poor motility)

    TTC since 01/2012

    11/2012-04/2013 Unmonitored Clomid cycles through OB/GYN; Referred to RE

    05/2013-Benched due to cyst

    06/2013 - Clomid 50 mg + HCG Trigger + TI = BFN

    07/2013 - Clomid 50 mg + HCG Trigger + IUI #1 = BFN

     08/2013 - Clomid 50 mg + HCG Trigger + IUI #2 = BFN

    09/2013 - Benched for lap & hysteroscopy (Stage II Endo Removed)

    10/2013 - Menopur + HCG Trigger + IUI #3 = BFN

    11/2013 - Menopur + HCG Trigger + IUI #4 = BFN

     12/2013 - Clomid + HCG Trigger + IUI #5 = BFN

    2/2014 - IVF #1 - Microdose Lupron Flare Protocol - 5R/4M/4F w/ICSI; 2 embies transferred on day 3 (none to freeze)

    2/27/14 - First BFP Ever!!!  EDD 11/3/14

     

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  • There is a lot to IVF yet if you take it one day at a time and hang around here, you'll learn a lot.  You can do this!  PP was right that weight gain/bloating and mood swings are coming your way.  If you want tips, I wrote a blog post in Oct of last year (link to my blog in sig) with some advice that's too long to re-write here as I was going through our first IVF.  

    We did ICSI (and will do again in June).  It gives you a higher chance of fertilized eggs after retrieval, so I think of it as a good thing that can help us MFI'ers.  Honestly I've never heard of the higher chance of birth defects so I wonder what research they have suggesting that.  Our first IVF gave us a "genetically normal male" (we learned from genetic testing) before we had a missed miscarriage around New Years.  

    But welcome, and stick around!

    TTC since July 2009. Dx MFI & LPD. 
    IUI#1&2&3 (2011 & 2012) BFN
    IUI#4 1/23/13 on 75iu x9 Follistim = BFP then chem preg m/c (Feb 2013)
    IUI#5 BFN (April 2013)
    IVF w/ICSI Oct. 2, 2012 - 13R, 11M, 7F, 1 frozen blast 4BB grade - - - FET Nov 15, 2013
    BFP! Beta 1:104 @ 10dp6dt, Beta 2:178 @ 12dp6dt,  beta 3:366 @ 14dp6dt
    Saw heartbeat twice before missed M/C at 8w3d on 12/27/13, missing my little angel boy
    JUNE 2014 IVF#2;  5R, 2M, 1F Three day transfer 6/7.  Beta 6/18 - BFN
    Child Free Now?
    S/PAIFW , S/PALW

    My Blog

    image



  • Welcome and I am sorry you have abruptly found yourself here, many of us worked our way up to IVF, jumping right in for you may be very difficult.  As hard as it is, try and have comfort knowing you now have some answers. 

    As for IVF, it's a brutal, emotional process but for those of that it doesn't work, we keep coming back for more so also have comfort in knowing that no matter how emotional, painful, and hard it gets, the anticipated result is still worth it. 

    I just finished my first IVF with ICSI cycle.  My RE always does ICSI even for couples with normal sperm count because they find it better to know for sure each embryo had a chance to fertilize.  In your case it sounds like the best option, although, be prepared, it is more expensive.  We are lucky to have some insurance coverage (not for much longer but we do now) and hopefully you do too.  

    Like someone said, take i one day at a time... it's a process but stay close on these boards and you will learn a lot, we are here for you. 
    Siggy Warning... loss mentioned

    Married since March 2008 -- Me- 31    DH - 30  Trying to grow our family since 2009... Diagnosed Unexplained Infertility 

    Started seeing RE Aug 2013

    Cycle #1  – IUI #1  10.31.13 - BFN

    Cycle #2 - IUI #2 cancelled – FAIL

    Cycle #3 - IUI #2 12.27.13  BFN

    Cycle #4 -  IUI #3 1.24.14  BFN

    Cycle #5 - IVF #1 with ICSI(2 3bb blasts) 3.19.14, no frosties.. BFN


    Surprise BFP on 6.10.14 ... Miscarried 7.7.14 


    Walked away from Fertility Treatments and began to look into our Foster/Adopt License in April 2014.


    Our Journey Blog...  http://salatafamilyest2008.blogspot.com/


  • Thank you all for the kind words. It's so helpful knowing there is such a supportive community out there of people who are facing similar situations. I'm ready to put my body through whatever it takes if it helps lead toward the goal of a baby. Bring it on!
    TTC: August 2013
    Me: Age 30/Diagnosis: low ovarian reserve
    DH: Age 30/Diagnosis: low sperm count/quality

    IVF #1: August 2014=BFN
  • *loss mentioned*

    I'm sorry you find yourself here.  Infertility is a tough road, but IVF and ICSI may help you tremendously.  We did IVF with ICSI and although it was physically demanding and emotionally draining, support from your significant other helps you through the entire process.  My clinic also does ICSI on at least half the eggs (with ours they did it with all 24).  It is often your best chance at getting as many embryos as possible and then getting to freeze some so you dont have to do a fresh cycle again.  I did hear that the risk of abnormalities was higher, but it was very small.  I can say this - IVF was no cakewalk, and we lost our twins at 22.5 weeks (who were both perfect - our loss had nothing to do with IVF), but I am still proceeding with an FET in May.  @ejrobbi said it best - it is a hard journey but we keep coming back for more.  Plus, remember that everyone reacts differently to IVF.  My worst side effect was slight bruising at injection sights and possible OHSS (which I never actually got).  I didn't have the mood swings people normally get, nor the weight gain, etc.  I wish you the best of luck.  
  • It's a tough question to answer in just one post but let me start with this... IVF is certainly not easy but absolutely do-able. You will get through it and this initial phase does usually get easier. Once you start gathering information it begins to make more sense and you will likely begin to feel less overwhelmed. For now give yourself the time and space to process it and know that feeling overwhelmed is so common and that and whatever else you are feeling is absolutely ok. IVF = an emotional free pass - IMO!

    My advice is do lots of research, ask lots of questions and find support. This is a great way to start but also look into in-person options. Many non-profits and clinics also off peer groups, therapist led groups etc.

    Finally, in a nutshell...the old adage of hope for the best, plan for the worst and expect the unexpected is good way to deal with IVF.

    Best of luck on your journey and I hope you are feeling better soon. Sending strength and love!

    Stephanie

     

     

     

     

  • Welcome!

    I am looking into my first IVF also.  I am excited, hopeful and terrified.  Mostly terrified of not being able to pay for the next step or the meds.  It is a brutal process but the award is amazing.

    Good luck to you! And all of us waiting and fighting!
    TTC since 2007; Unexplained; 8PG: 4CP, 2EP, 2MC w/HB at 8-9 weeks
    Getting ready for DIVF #1 - Transfer 12/16! 
  • We did ICSI and our doctor never told us that it increased the risk of birth defects. The only thing I'd read on that was that it could pass on fertility issues to future sons. 

    But, obviously, I am a firm believer in ICSI. Especially in the case of MFI. 

    N14 Nov. Siggy: CELEBRATION!

    image image
    TTC since 2011
    Aug. - Sept. 2013 - dIUIs = BFNs
    January 2014 - IVF = 3 freezer babies
    March 2014 - FET of AA and AB blast = BFP! Twins! 
    Nov. 7, 2014 - Wilhelmina "Willa" Suzanne (4lb 14oz) and Ari Jose (6lb 4oz) were born via CS
    image image
     
    image image image image 

    Lilypie Premature Baby tickers
  • We too did ICSI. Until reading this post I didn't know there was a risk of birth defects either.

    Everybody will take their cycle differently. DH and I have always joked our way through hard times so we did it again through IVF. Be careful who you let into this world with you. Even the best intentions can be offensive at some point if the person has no idea what you're actually going through. BUT at the same time, try not to take offense. People just don't realize how hard this really is.

    I had ALL the side effects... Moody, nausea, vomiting, bruising, insomnia... Plus, maybe a little depression as I shut myself off from almost everybody.

    You're definitely in the right place. These ladies are a wealth of support and knowledge!

    Best of luck to you!
  • My doctor also sited the 2% higher chance of birth defects with icsi but stressed that premature birth was included in that and also, it was hard to suss out how much higher the chance really was vs the fact that IVF births are studied so much more than natural births. He was not concerned with the statistic and put my mind at ease about it too.

    To the OP: as others have said: it's not an easy road, but it's totally doable! This board is a great resource. Good luck!!
    ----
    *I am no longer regularly posting on TB because of the fucked up debacle of Jan 2015 when administrators banned long-term members and mods with no notice and completely dismantled a community full of women who cared about each other.  If you see me posting it's only to give support to a poster who needs it or to post something important enough that I need to say.  I am no longer responding to  anything other than issues that affect people who I care about*
    37 years old, MH is 42
    TTC since 2010; Dx Unexplained Infertility; possible male factor 
    August 2012 through June 2013:  6 IUIs with clomid and trigger shot, all BFNs
    7/2013, Pregnant! Unmedicated--we were on a treatment break
    8/20/13 no heart beat; 8/23/13 d&c
    3/15/14 IVF #1:  Lupron/Follistim/Menopur; ER 3/10 resulting in four transfer grade blastocysts, transferred one pretty blast and froze the remaining three. BFN. 
    Natural FET in May cancelled because the universe hates me my hormones were not cooperating.
    6/24/14 FET #1: transferred two pretty embryos; BFN   
    8/28/14 FET #2: BFP, ended in Chemical pregnancy

    Done with medical intervention and getting used to the idea of CFNBC.  




    All welcome
  • We will be attempting IVF w/ ICSI in the near future... we are male factor as well.  So I just wanted to say hi & good luck  :)

    ****siggy warning****

    Me 29/ DH 28
    DH- MFI (low count, 2-3% morph)

    IUI #1 January - Clomid, Ovidrel: BFN
    IUI #2 February - Letrozole, Follistim, Ovidrel: BFP 1st beta-25, 2nd beta-56, 3rd beta-45, miscarriage
    IUI #3 April - CD3 U/S 4-10. Letrozole, Follistim, Ovidrel CD11 - Cancelled.. TI w/5 follicles-BFN
    IUI #3.1 May - CD3 U/S 5-6, Follistim start 5-11 thru 5-17, u/s 5-18 3 mature w/ a close 4th, IUI 5-20 - BFP!
                 Beta #1 12dpo - 164 & progesterone - 89!, Beta #2 16 dpo - 1189, 5w3d - u/s shows TWINS!
                 6/19- u/s showed heartbeats! Baby A 111 & Baby B 118, both measuring 6w1d
                 7/3- Baby A hb 170, Baby B hb 166 - both measuring perfect.
                 7/18 - Baby A 165, Baby B 171 - both measuring right on track & moving all around!

    image

    Pregnancy Ticker

  • Coming in from PAIF (siggy warning).

    Our fertility issues were related to MFI, specifically low motility.  My husband's motility was 0% and then went up to 40% (possibly due to an uncommon side effect of taking propecia).  After 3 failed IUIs, we moved forward with IVF with ICSI.  Out of the18 eggs retrieved, 14 were mature and all 14 of them fertilized via ICSI.  Out of those 14, 8 made it to blastocyst phase.  Our first IVF didnt' work, but the FET worked.

    Our RE didn't mentioned anything about increased birth defects, but so far everything is good.  Best of luck in your journey, this board was super helpful and supportive. 
    <a href="http://www.thebump.com/?utm_source=ticker&utm_medium=HTML&utm_campaign=tickers" title="Getting Pregnant"><img src="http://global.thebump.com/tickers/tt1bbf31.aspx" alt=" Baby Birthday Ticker Ticker" border="0"  /></a>
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