Infertility

Question about E2 #'s and egg maturity (xp)

So my last IUI was a BFN... I used Menopur and Ovidrel.  I was told by the nurse the day before the IUI that everything looked great and I had 3 mature follies and one "maybe"... I just looked through all my lab work from that cycle and my Estradoil reading the day before the IUI was only 176  so how could I have 3"mature" follies ...shouldn't it have been much much higher? By ultrasound they appeared mature  but not according to the blood work from what I have researched thus far...

 I am moving on to IVF so this is a mute point in some ways ( what is done is done) but now I am worried inside my "large" follies there are nothing but just little crappy immature eggs.  I plan on asking about this next week when I go in, but thought maybe you ladies might have some input here...   I am hardcore stressing and I haven't started stimms yet!
***siggy/ticker warning***

Me:36 DH:38 TTC#1 since 4/2012
Me DX: Hashimotos,Hypothyroid, DOR, MTHFR,  DH: normal

 IUI #1-#4 BFNs and a few cancelled cycles in the mix.
- poor responder
***Suprise BFP on 6/13/13. Natural MC @6wks 3days
IVF#1 and 2- Cancelled due to no response on max stimms
FET 5/20- BFP
1st Beta- 641
2nd beta- 2166
Sono- TWINS!!!!
Two Boys! Born January 2015 @36 weeks.  Healthy and no NICU!  So blessed!



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Re: Question about E2 #'s and egg maturity (xp)

  • That is surprising... each mature follicle produces about 100-200 units of estradiol, so 176 total for three "mature" follicles doesn't add up. 

    What meds are you using for IVF? Are you adding FSH to the mix?
    **SIGGY WARNING**

    Me: 32 DH: 35  TTC#1 since March 2012
    Dx: Poor Embryo Quality, Arcuate Uterus, Poor Uterine Blood Flow, Mild Endo, 
           Protein S Deficiency, Sjorgen's Syndrome 

    IUI #1-5: BFN
    Laparoscopy & Hysteroscopy: minimal endo, partial septoplasty
    IVF #1: 10R/6M/6F ~ Day 3 ET = BFN
    IVF #2: 14R/9M/5F ~ transfer canceled ~ all embryos arrested at 1-2 cell stage
    IVF #3: 9R/5M/5F ~ 1 frosty!
    IVF #4 (FET #1): BFN

    IVF #5 (DE IVF #1 with Dr. KK protocol): Currently PREGNANT!!!!!!
    Synthroid + Prednisone + Metformin + Baby Aspirin + Supplements Galore = 15+ pills a day
    Lupron + Lovenox + Delestrogen + IVIG + B/W = 2-5 pokes a day
    19R, 17M, 17F - transferred two Grade A blasts 11/16, four frosties!!!
    Beta #1 11/24 (13dpo/8dp5dt) = 367 ~ Beta #2 11/26 (15dpo/10dp5dt) = 709
    Beta #3 11/29 (18dpo/13dp5dt) = 1,997 ~ Beta #4 12/1 (20dpo/15dp5dt) = 3,403

    imageimageimage

    My Blog: Running and Dreaming for Two ~ All are Welcome!
  • I'm using max of menopur and Ganirelix with hcg trigger
    ***siggy/ticker warning***

    Me:36 DH:38 TTC#1 since 4/2012
    Me DX: Hashimotos,Hypothyroid, DOR, MTHFR,  DH: normal

     IUI #1-#4 BFNs and a few cancelled cycles in the mix.
    - poor responder
    ***Suprise BFP on 6/13/13. Natural MC @6wks 3days
    IVF#1 and 2- Cancelled due to no response on max stimms
    FET 5/20- BFP
    1st Beta- 641
    2nd beta- 2166
    Sono- TWINS!!!!
    Two Boys! Born January 2015 @36 weeks.  Healthy and no NICU!  So blessed!



    image 

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  • Sunny BSunny B member
    edited January 2014
    I will say that my E2 reading from the morning of trigger or before trigger- I forget (took the trigger shot at night) did not show that I had 16 mature eggs at all! It was around 1200. So I think it really jumps that day after trigger.
    TTC since May 2012
    Me: 32 H: 31
    DX: MFI-Very Low Count, I have Hashimotos.
    IVF prep September 2013 cancelled due to Ovarian Cyst
    IVF #1 October 2013 Antagonistic Protocol with ICSI  ER 10/31/13 (18R 16M 11F- 6 blasts to freeze)
    ET delayed due to OHSS 
    FET scheduled for July 8. Delayed due to a crazy high TSH (it had been under control for YEARS!)
    FET #1 8/5/14 sET BFN 

    All welcome!
  • My e2 levels with my cycles were approximately:

    850 = 8 mature
    900 = 6 mature
    1100 = 6 mature
    1500 = 10 mature 

    I agree that your numbers are a little low to have had 3 mature eggs in your follicles. Definitely ask about it and best of luck to you on your next attempt.

    Age: 35 TTC since 2005, MFI & DOR 

    IVF #1 Sep '11 - canceled poor response

     IVF #2 Nov '11  8R/8M/4F 3dt x2 - chemical

    IVF #3 April '12  11R/6M/4F 3dt x2 - m/c

    FET #1 Aug 2012  3dt x2 - BFN

    **new RE**

     IVF #4 Jan '13 BFN 11R/6M/6F 5dt x2 - BFN

     IVF #5 July '13 16R/10M/10F 5dt x2 + 1 frostie

    9dp5dt Beta 1 = 344!! 16dp5dt. Beta 2 = 4822 7wk u/s= 2 heartbeats!

    Twin girls! 3/6/14

     

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