This is a place for those of us who have already started TTC, but
have started infertility testing and/or treatments. You can express your
thoughts, feelings, and frustrations on infertility. TTC can be a long
journey naturally, then add in the difficulties associated with
infertility, and it becomes a whole new ballgame. The road to
infertility can be lonely, frustrating, and complicated, so let's make
this a place where we can vent, ask questions, and support one another.
Feel free to resurrect this thread at any point in the week if you have
something to say. Treat this as an ongoing conversation.
Diagnosis (if you've been):
Status (TI/ICI/IUI/IVF/FET/benched):
What are you doing this cycle? (Testing? Treatment?):
How are things going?:
Any questions?:
Re: IF Testing and Treatment w/o 7/25
Diagnosis (if you've been): DOR, LPD, unexplained
Status (TI/ICI/IUI/IVF/FET/benched): TI
What are you doing this cycle? (Testing? Treatment?): letrozole for the first time.
How are things going?: going well! Feeling very optimistic. We had perfect timing with 2-3 follicles and an over 9mm lining. We gave it everything we had so if this cycle doesn’t work, we’ll try IUI again now that we know my body likes letrozole.
Any questions?: nope
GTKY: In the evening, would you rather play a game, visit a relative, watch a movie, or read? Depends on the day of the week. During the weekdays is mostly watch tv and/or read. Weekends we like to watch movies and play card games.TTC: Sept 2016-Oct 2017
BFP Oct 2017. DD born July 2018.
TTC: March 2020. BFP March 2020
Due date was Nov 2020
DS born Sept 2020. DS passed away Nov 2020 due to prematurity and birth trauma.
TTC: March 2021
IUI #1 Nov 2021, BFN
IUI #2 Dec 2021 BFP. MC Jan 2022
IUI #3 Aug 2022 BFN
IUI #4 Sept 2022 BFN
AMH test came back at .081. Was going to move on to IVF with DE, but have decided not to. Will be leaving it up to the universe now.
Diagnosis (if you've been): PCOS, RPL/RIF, some MFI, and The Fibroid
Status (TI/ICI/IUI/IVF/FET/benched): WFFET #8 on Saturday July 30th
What are you doing this cycle? (Testing? Treatment?): Mini-stim FET with Puregon, HCG trigger, PIO, prednisone, metformin, baby aspirin, intralipids, PRP, Nivestym (Neupogen), medrol, doxycycline, HCG wash, embryo glue. Plus my usual vitamin/supplement regimen (AM is L-arginine, NAC, Vit C, Vit E, Vit B12, Ovasitol; lunch probiotics, Omega3, NAC, methylfolate, zinc, Vit D; dinner/evening L-arginine, Omega3, Ovasitol, melatonin)
How are things going?: They're going. I did my PRP and triggered on Saturday morning and based on my extremely crampy ovaries last night things are definitely moving along. Lead follicle was around 21mm, with 2 more in the 15-16mm range and we HIO Friday and last night for good measure. Went this morning for my first of 2 intralipid sessions, go again Thursday for another PRP and lipids, FET is Saturday. Still haven't decided if we're transferring one or two yet. On the one hand, it gives us two chances. On the other hand, am I 'wasting' an extra embryo if we can't even get one to implant? Sigh.
Any questions?: Not unless you want to weigh in on my double transfer dilemma.
GTKY: In the evening, would you rather play a game, visit a relative, watch a movie, or read? Ooh, if it's a week/work night then we like to unwind by watching a tv show or a movie, but on weekends I do like to get together with family. That often involves playing a game. DH is currently obsessed with something called, Popdarts, has anyone else ever heard of them? I paid a stupid amount of money to get him a set of what is essentially suction cup darts, and it turns out it's actually kind of fun but I'm terrible at it lol.TTC History:
Me: 36 MH: 39, TTC since Dec 2017
Aug '18: PCOS dx
Nov '18: MH SA - 19mil
Dec '18-Mar '19: Letrozole + TI - all BFN
Apr '19: Letrozole + TI, - BFN. Repeat SA (27mil) & DNA fragmentation test (17%)
Aug '19: Letrozole + HCG trigger + IUI + prog supp - BFN (MH: 16mil)
Sep '19: 2nd IUI, same protocol - BFN (MH: 16mil)
Dec '19: IVF #1 w/ICSI, PGT. 5 retrieved, 4 fertilized, 3 blasts, 3 PGT-A normal.
Mar '20: FET #1, perfect 5AA blast transferred. BFN.
Sept '20: FET #2, 5BB tsf. 9/18/20 BFP!! EDD: 5/27/21. MMC 11w
Feb ‘21: FET #3, last 6BB blast transferred. BFP, EDD 11/2/21. MC 5w3d.
May '21: IVF #2 w/ICSI, PGT. 8R, 7M, 6F, 6 blasts - 3AB, 3AB, 3BB, 4BB, 5BB, 6BA. Fresh tsf 5/13/21 - BFN.
June '21: PGT-A results = 3 abnormal, 1 low level mosaic. Referred to new REI, had consult with 2nd RE in between.
Sept '21: RPL, immune testing normal
Oct '21: IVF #3 w/IMSI, PGT. 33R, 26M, 23F, 9 blasts (7 day 6, 2 day 7). PGT-A = 5 normal, 1 mosaic
Dec '21: Positive for endometritis, RX Flagyl & Keflex
Jan '22: FET #5 - Kitchen sink immune/RIF protocol incl. PRP, intralipids, prednisone, medrol, nivestym, fragmin - CP
Feb '22: FET #6 - Kitchen sink immune/RIF protocol w/higher doses of pred & fragmin - BFN
Mar '22: Mock cycle for ERA - cancelled, repeat endometrial biopsy instead. Still positive for endometritis. RX ciprofloxacin & amoxicillin.
Apr '22: IVF #4 w/IMSI, PGT. 28R, 23M, 16F, 11 blasts. PGT-A = 6 normal.
June '22: FET #7 - Microdose lupron downreg w/kitchen sink immune/RIF protocol - double embryo transfer. BFN.
July '22: FET #8 - Mini stim w/Puregon + trigger, kitchen sink immune/RIF protocol. BFN.
Sep '22: Taking a break
Dec '22: Attempted abdominal myomectomy, fibroid too close to cervix and major blood vessels. Wasn't removed.
Feb '23: FET #9 - Modified natural w/baby asp, HCG trigger, PIO, PRP, Medrol, HCG wash, embryo glue - BFP!! EDD 11/11/23
Diagnosis (if you've been): Old, LPD, RPL, MTHFR, ANA Positive
Status (TI/ICI/IUI/IVF/FET/benched): Benched
What are you doing this cycle? (Testing? Treatment?): I'm waiting to ovulate (I think it will be tomorrow) so that I can call the doctor's office and schedule some bloodwork. They're going to check my B6 and B12 vitamins as well as do a full thyroid panel and a progesterone test.
How are things going?: They're going! I spoke to a nurse on the phone the other day to schedule bloodwork and she went over my protocol once I get cleared from the rheumatologist. The nurse said that I would start 200mg of progesterone after ovulation and I was like, "I'm gonna stop you right there. I need at least 400. 200 won't work. I don't want to waste your time or my time. I know my body, give me the drugs." She said that she would make a note, but Lord help me. I have some progesterone in my medicine cabinet and if this place doesn't prescribe me enough I will just fix the amount with my own supply.
Any questions?: I've seen quite a few women using prednisone while TTC or while PG. Is this just for specific cases or is it beneficial to anyone? I'll bring it up with my doctor.
GTKY: In the evening, would you rather play a game, visit a relative, watch a movie, or read? I read a little bit every night before going to bed, but I LOVE playing games! Unfortunately, we don't live near family and don't have any real friends where we live so we don't play that much. However, I did get a Nintendo Switch so I can play Mario Kart with my mom and sister. So fun!@elle-0409 we're seeing more and more use of prednisone for women with suspected underlying auto-immune conditions to help calm the immune system, however I would caution its use outside of medicated cycles because it can disrupt or delay natural ovulation. // re: Popdarts, it's fun for all ages, it's like a mix between darts and bocce. There's a 'target' dart and you have to get your darts to land as close to the target as possible. They're just these rubber double-ended suction cup things so they're gentle and you can play them basically anywhere that there's a surface that they'll stick to. We were throwing them at our back door because it has a glass window but it works really well on a kitchen table or island. *TW* Our 3.5 y/o nephew just had fun throwing them, even he understood that he had to try to get it close to the target. DH and BIL mostly used him to retrieve the darts and bring them back to them lol.
TTC History:
Me: 36 MH: 39, TTC since Dec 2017
Aug '18: PCOS dx
Nov '18: MH SA - 19mil
Dec '18-Mar '19: Letrozole + TI - all BFN
Apr '19: Letrozole + TI, - BFN. Repeat SA (27mil) & DNA fragmentation test (17%)
Aug '19: Letrozole + HCG trigger + IUI + prog supp - BFN (MH: 16mil)
Sep '19: 2nd IUI, same protocol - BFN (MH: 16mil)
Dec '19: IVF #1 w/ICSI, PGT. 5 retrieved, 4 fertilized, 3 blasts, 3 PGT-A normal.
Mar '20: FET #1, perfect 5AA blast transferred. BFN.
Sept '20: FET #2, 5BB tsf. 9/18/20 BFP!! EDD: 5/27/21. MMC 11w
Feb ‘21: FET #3, last 6BB blast transferred. BFP, EDD 11/2/21. MC 5w3d.
May '21: IVF #2 w/ICSI, PGT. 8R, 7M, 6F, 6 blasts - 3AB, 3AB, 3BB, 4BB, 5BB, 6BA. Fresh tsf 5/13/21 - BFN.
June '21: PGT-A results = 3 abnormal, 1 low level mosaic. Referred to new REI, had consult with 2nd RE in between.
Sept '21: RPL, immune testing normal
Oct '21: IVF #3 w/IMSI, PGT. 33R, 26M, 23F, 9 blasts (7 day 6, 2 day 7). PGT-A = 5 normal, 1 mosaic
Dec '21: Positive for endometritis, RX Flagyl & Keflex
Jan '22: FET #5 - Kitchen sink immune/RIF protocol incl. PRP, intralipids, prednisone, medrol, nivestym, fragmin - CP
Feb '22: FET #6 - Kitchen sink immune/RIF protocol w/higher doses of pred & fragmin - BFN
Mar '22: Mock cycle for ERA - cancelled, repeat endometrial biopsy instead. Still positive for endometritis. RX ciprofloxacin & amoxicillin.
Apr '22: IVF #4 w/IMSI, PGT. 28R, 23M, 16F, 11 blasts. PGT-A = 6 normal.
June '22: FET #7 - Microdose lupron downreg w/kitchen sink immune/RIF protocol - double embryo transfer. BFN.
July '22: FET #8 - Mini stim w/Puregon + trigger, kitchen sink immune/RIF protocol. BFN.
Sep '22: Taking a break
Dec '22: Attempted abdominal myomectomy, fibroid too close to cervix and major blood vessels. Wasn't removed.
Feb '23: FET #9 - Modified natural w/baby asp, HCG trigger, PIO, PRP, Medrol, HCG wash, embryo glue - BFP!! EDD 11/11/23
TTC: Sept 2016-Oct 2017
BFP Oct 2017. DD born July 2018.
TTC: March 2020. BFP March 2020
Due date was Nov 2020
DS born Sept 2020. DS passed away Nov 2020 due to prematurity and birth trauma.
TTC: March 2021
IUI #1 Nov 2021, BFN
IUI #2 Dec 2021 BFP. MC Jan 2022
IUI #3 Aug 2022 BFN
IUI #4 Sept 2022 BFN
AMH test came back at .081. Was going to move on to IVF with DE, but have decided not to. Will be leaving it up to the universe now.
@bearmomma1 that's a really good point about this being a modified natural cycle as well, which we've never done before. There are essentially two main ways you can prepare for a FET - by doing a "natural" cycle where you time it with your own ovulation (which is sometimes assisted by medications to do so, like letrozole, stims, and/or a trigger shot, hence "modified" natural), or a full medicated cycle where you would be taking estradiol to build your lining from about CD2/3 which would prevent you from ovulating at all, and you time the transfer based on when you start progesterone. I've only ever done the latter. Granted we've been TTC "naturally" since 2017 and have never once gotten pregnant without IVF so I'm not really expecting much but our RE was very much on the same page as us in thinking we could hedge our bets that way and also HIO to give us an extra shot at it. Maybe it's naive not to be concerned about the prospect of multiples because we can't even get one to stick, but with this possibly being one of our last transfers before moving on to surrogacy, maybe it's worth the risk.
TTC History:
Me: 36 MH: 39, TTC since Dec 2017
Aug '18: PCOS dx
Nov '18: MH SA - 19mil
Dec '18-Mar '19: Letrozole + TI - all BFN
Apr '19: Letrozole + TI, - BFN. Repeat SA (27mil) & DNA fragmentation test (17%)
Aug '19: Letrozole + HCG trigger + IUI + prog supp - BFN (MH: 16mil)
Sep '19: 2nd IUI, same protocol - BFN (MH: 16mil)
Dec '19: IVF #1 w/ICSI, PGT. 5 retrieved, 4 fertilized, 3 blasts, 3 PGT-A normal.
Mar '20: FET #1, perfect 5AA blast transferred. BFN.
Sept '20: FET #2, 5BB tsf. 9/18/20 BFP!! EDD: 5/27/21. MMC 11w
Feb ‘21: FET #3, last 6BB blast transferred. BFP, EDD 11/2/21. MC 5w3d.
May '21: IVF #2 w/ICSI, PGT. 8R, 7M, 6F, 6 blasts - 3AB, 3AB, 3BB, 4BB, 5BB, 6BA. Fresh tsf 5/13/21 - BFN.
June '21: PGT-A results = 3 abnormal, 1 low level mosaic. Referred to new REI, had consult with 2nd RE in between.
Sept '21: RPL, immune testing normal
Oct '21: IVF #3 w/IMSI, PGT. 33R, 26M, 23F, 9 blasts (7 day 6, 2 day 7). PGT-A = 5 normal, 1 mosaic
Dec '21: Positive for endometritis, RX Flagyl & Keflex
Jan '22: FET #5 - Kitchen sink immune/RIF protocol incl. PRP, intralipids, prednisone, medrol, nivestym, fragmin - CP
Feb '22: FET #6 - Kitchen sink immune/RIF protocol w/higher doses of pred & fragmin - BFN
Mar '22: Mock cycle for ERA - cancelled, repeat endometrial biopsy instead. Still positive for endometritis. RX ciprofloxacin & amoxicillin.
Apr '22: IVF #4 w/IMSI, PGT. 28R, 23M, 16F, 11 blasts. PGT-A = 6 normal.
June '22: FET #7 - Microdose lupron downreg w/kitchen sink immune/RIF protocol - double embryo transfer. BFN.
July '22: FET #8 - Mini stim w/Puregon + trigger, kitchen sink immune/RIF protocol. BFN.
Sep '22: Taking a break
Dec '22: Attempted abdominal myomectomy, fibroid too close to cervix and major blood vessels. Wasn't removed.
Feb '23: FET #9 - Modified natural w/baby asp, HCG trigger, PIO, PRP, Medrol, HCG wash, embryo glue - BFP!! EDD 11/11/23
TTC: Sept 2016-Oct 2017
BFP Oct 2017. DD born July 2018.
TTC: March 2020. BFP March 2020
Due date was Nov 2020
DS born Sept 2020. DS passed away Nov 2020 due to prematurity and birth trauma.
TTC: March 2021
IUI #1 Nov 2021, BFN
IUI #2 Dec 2021 BFP. MC Jan 2022
IUI #3 Aug 2022 BFN
IUI #4 Sept 2022 BFN
AMH test came back at .081. Was going to move on to IVF with DE, but have decided not to. Will be leaving it up to the universe now.
@kiki047 Sending you all the good vibes as you make your transfer decision. Trust yourself, friend. Popdarts look like so much fun. Definitely keeping that in mind for future gifts!
@elle-0409 We love playing games too! Board games and video games. Our new favorite that we recently acquired is called For Science! It is a geeky, fast-paced, cooperative game. What are some of your favorites?
Diagnosis (if you've been): RPL, old eggs, unknown
Status (TI/ICI/IUI/IVF/FET/benched): TI
What are you doing this cycle? (Testing? Treatment?): Second cycle of clomid, just gearing up to start HIO in a few days.
How are things going?: My new job is way more stressful than I thought it would be. I think it will settle down in a few weeks when I feel a little more comfortable with the planning aspect, but right now it is pretty overwhelming. Hoping the stress doesn't negatively impact O or our chances this cycle. Gotta love when added stress makes you stress even more.
Any questions?: Realistically, I'm not sure we can HIO more than 3 times in fertile week. I just can't get my H on board for more than that. I obviously know that one time is technically enough any given month, but are our chances significantly damaged without the ability to marathon HIO? I do have the luxury of a fairly consistent O each month, so at least a couple times are usually on peak days.
GTKY: In the evening, would you rather play a game, visit a relative, watch a movie, or read? I love to play a game! If I'm tired though, I enjoy watching something not stressful. I usually read 20 minutes or so before bed.Diagnosis (if you've been): old and grouchy
Status (TI/ICI/IUI/IVF/FET/benched): IVF
What are you doing this cycle? (Testing? Treatment?):
still bleeding, just inserted birth control and now waiting for the start of my final stimulation cycle in september.
How are things going?:
i'm a little worried that i'm going to be on BC for longer than is ideal. it's just the way my cycle and the clinic's calendar overlap and nothing much to do about it. other than that, i feel ok. i'm trying to make the most of this last cycle by being a little more careful about my alcohol than i was last cycle and also by adding back into my supplements regimen the melatonin. i'd dropped it out for the last couple of cycles because it makes me a little groggy in the mornings, but i'd sort of forgotten that apart from CoQ10 and vit D, it's the other thing that i have in my cabinet that seems to have solid-ish data behind it. also upping my CoQ10 game from the standard stuff to ubiquinol. that sh** is expensive. and also, i don't really believe in any of it particularly. but as this is my last rodeo, may as well.
Any questions?: nah.
GTKY: In the evening, would you rather play a game, visit a relative, watch a movie, or read?Oct '21 somewhat improved AMH (.51) and significantly improved FSH (8.9). Maybe it's all the pills I swallow.
Dec -21, standard antagonist. 225menupur/225gonal-f/cetrotide/5000u trigger, AFC 5; 11 days of stims. retrieval yields 5, 4M, 2 reach day-6 blast (4AB & 4BB). 1 low-level mosaic (chr. 3 deletion), 1 complex abnormal.
Feb '22 FET (low-level mosaic): CP.
May '22 egg retrieval, lupron flare protocol. HGH priming for 1 month before stims; md lupron 20/20u daily; menopur 225, follistim 225, 10k trigger after 8 days of stims; AFC 10; 13 retrieved; 10 mature; 8 fertilized. All frozen at 2PN for later thaw, grow, and biopsy.
July '22 egg retrieval same protocol: 9 days of stims; AFC 8; 10 retrieved, 8 mature, 4 fertilized and frozen.
Sept '22 ER same protocol: AFC 10; 12 retrieved, 11 mature, 11 fertilized.
From the 3 retrievals, 7 survived to day 5-6 blastocyst, from which I have 2 normal embryos!
Jan 20, Fully medicated FET, baby aspirin, dexamethasone, acupuncture, and as much woo as I can stand (which isn't very much). BFN.
July 23, Natural FET + baby aspirin. BFN.