Trying to Get Pregnant

Ten Things Tuesday July 5


Our good friend @keikilove used to post this thread every week, and even though under other circumstances I might have found it a little Hallmark-greetings-cardish, I always loved the exercise.
What ten simple things are you feeling grateful for this week? List them below!

History
I am doing this on my own. Left ovary and fallopian tube removed due to cyst/necrosis just after birth. Right ovary and tube still purport to function.
Began TTC in Aug '18 @ age 35
5 or 6 (or 7?!) cycles using frozen donor sperm, ICI. All BFN
Mar-Jun '19 IUIs, all BFN
Began process of referral for RE in spring of '19, blood tests confirm low AMH (.54) but all else is good.
May '19 HSG shows open tube, but ultrasound suggests fibroids
MRI in June '19 confirms two large fibroids, one growing through wall of uterus
In June '19 I move from California to Oregon, disrupting my insurance, referrals, etc. 5 months spent piecing it all back together.
Nov. '19 attempted myomectomy (vaginal approach) failed. 2nd surgery using laparoscopic method in Jan '20 is successful.
April '20 --> June '20, natural IUIs, all BFN.
July? saline ultrasound and bubble test demonstrate open tube
July '20 clomid cycle cancelled for thin lining
Aug-Oct, 3 femara cycles, all BFN
RE referral. While waiting to set up an appointment Nov-Jan,I continue with natural cycles and ICI, using a known donor, BFN...
Jan '21 more bloodwork, AMH is worse (.30), FSH high albeit not catastrophic at 13.2. hysteroscopy all good. "looks cozy!" says the RE.
Feb '21, injectables (menopur, novarel), iui, BFN (doc said the frozen donor sperm sample had the "best numbers she'd ever seen!")
Mar '21, injectables, iui cancelled due to lack of follicles, converted to at home-insem. BFN
May '21, first IVF round cancelled due to cyst.
July '21 IVF: standard antagonist. 225menupur/225gonal-f/cetrotide/5000u trigger, AFC 7; 6 days of stims. 8 eggs retrieved, 7 mature, 5 fertilize, 4 made it to blast. 3 are 4AB, 1 is 4BB. PGT-A results all abnormal.
Oct '21 somewhat improved AMH (.51) and significantly improved FSH (8.9). Maybe it's all the pills I swallow.
Dec -21, standard antagonist. 225menupur/225gonal-f/cetrotide/5000u trigger, AFC 5; 11 days of stims. retrieval yields 5, 4M, 2 reach day-6 blast (4AB & 4BB). 1 low-level mosaic (chr. 3 deletion), 1 complex abnormal.
Feb '22 FET (low-level mosaic): CP.
May '22 egg retrieval, lupron flare protocol. HGH priming for 1 month before stims; md lupron 20/20u daily; menopur 225, follistim 225, 10k trigger after 8 days of stims; AFC 10; 13 retrieved; 10 mature; 8 fertilized. All frozen at 2PN for later thaw, grow, and biopsy.
July '22 egg retrieval same protocol: 9 days of stims; AFC 8; 10 retrieved, 8 mature, 4 fertilized and frozen.
Sept '22 ER same protocol: AFC 10; 12 retrieved, 11 mature, 11 fertilized.
From the 3 retrievals, 7 survived to day 5-6 blastocyst, from which I have 2 normal embryos!
Jan 20, Fully medicated FET, baby aspirin, dexamethasone, acupuncture, and as much woo as I can stand (which isn't very much). BFN.
July 23, Natural FET + baby aspirin. BFN.

Re: Ten Things Tuesday July 5

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  • Thanks for starting this one @optimistgardener!

    1. My family
    2. My job, and the fact that I am almost done with my training!
    3. financial security
    4. Iced coffee 
    5. my cake decorating hobby, and my husband for supporting it
    6. a short commute 
    7. a fabulous co-fellow/friend
    8. when my husband cleans or does laundry
    9. Costco
    10. not working weekends and no more call!
  • Coming back to add naps to my list. I don’t often nap but when I do it’s glorious!
  • D'aww, really missing our friend @keikilove this week. Thank you for starting the thread, @optimistgardener!

    1. My ride or die, always #1, DH. 
    2. Having the financial means to do things like IVF and travel
    3. Our pets; selfishly I'll always love my cat(s) more than DH's dog but Humpy is ok too I guess
    4. Modern healthcare, specifically vaccines, I could've been a lot sicker than I was
    5. Being Canadian - we're not perfect, but we have universal health care, reproductive rights, and gun control. 
    6. Good hair - maybe a little vain, but I only wash it once a week and it's nice and healthy. 
    7. Spandex. 'Nuff said? 
    8. My garden, it is one of my happy places.
    9. My blue light blocking glasses, because they save my eyes staring at a screen all day.
    10. As always, this community. I got to meet one of my oldest TTGP friends last week IRL and it was one of the best hugs I've ever gotten. Hoping to add some more of those kinds of meet-ups to my list soon!! 

    TTC History:

    Me: 36  MH: 39, TTC since Dec 2017

    Aug '18: PCOS dx

    Nov '18: MH SA - 19mil

    Dec '18-Mar '19: Letrozole + TI - all BFN

    Apr '19: Letrozole + TI, - BFN.  Repeat SA (27mil) & DNA fragmentation test (17%)

    Aug '19: Letrozole + HCG trigger + IUI + prog supp - BFN (MH: 16mil)

    Sep '19: 2nd IUI, same protocol - BFN (MH: 16mil) 

    Dec '19: IVF #1 w/ICSI, PGT. 5 retrieved, 4 fertilized, 3 blasts, 3 PGT-A normal.

    Mar '20: FET #1, perfect 5AA blast transferred. BFN.

    Sept '20: FET #2, 5BB tsf. 9/18/20 BFP!! EDD: 5/27/21. MMC 11w                                                  

    Feb ‘21: FET #3, last 6BB blast transferred. BFP, EDD 11/2/21. MC 5w3d. 

    May '21: IVF #2 w/ICSI, PGT. 8R, 7M, 6F, 6 blasts - 3AB, 3AB, 3BB, 4BB, 5BB, 6BA. Fresh tsf 5/13/21 - BFN. 

    June '21: PGT-A results = 3 abnormal, 1 low level mosaic. Referred to new REI, had consult with 2nd RE in between. 


    Sept '21: RPL, immune testing normal

    Oct '21: IVF #3 w/IMSI, PGT. 33R, 26M, 23F, 9 blasts (7 day 6, 2 day 7). PGT-A = 5 normal, 1 mosaic

    Dec '21: Positive for endometritis, RX Flagyl & Keflex

    Jan '22: FET #5 - Kitchen sink immune/RIF protocol incl. PRP, intralipids, prednisone, medrol, nivestym, fragmin - CP

    Feb '22: FET #6 - Kitchen sink immune/RIF protocol w/higher doses of pred & fragmin - BFN

    Mar '22: Mock cycle for ERA - cancelled, repeat endometrial biopsy instead. Still positive for endometritis. RX ciprofloxacin & amoxicillin. 

    Apr '22: IVF #4 w/IMSI, PGT. 28R, 23M, 16F, 11 blasts. PGT-A = 6 normal. 

    June '22: FET #7 - Microdose lupron downreg w/kitchen sink immune/RIF protocol - double embryo transfer. BFN.

    July '22: FET #8 - Mini stim w/Puregon + trigger, kitchen sink immune/RIF protocol. BFN. 

    Sep '22: Taking a break

    Dec '22: Attempted abdominal myomectomy, fibroid too close to cervix and major blood vessels. Wasn't removed. 

    Feb '23: FET #9 - Modified natural w/baby asp, HCG trigger, PIO, PRP, Medrol, HCG wash, embryo glue - BFP!! EDD 11/11/23


  • Love this @optimistgardener

    1. My husband (of 10 years in Sept, which is wild to think about). 
    2. TW - my daughter, who is 2.5, watching her little personality develop is a delight. 
    3. The financial means and desire to travel, and having a husband who has now been dragged to London 3x for Adele specifically. MH was so sweet and already asking/thinking about where we want to go next year. 
    4. Live music, because man it fills my soul. 
    5. Our pets - we have a dog and a cat, and they’re just both quirky but loving critters, and they are funny little friends with each other even.
    6. The extreme flexibility in owning my own business that I don’t have a finite number of hours off, especially with what feels like never ending Dr appts of late. And with that comes supportive and caring employees. I wish I could clone the three I have. 
    7. Living in a “blue” state when it feels like the US is an actual dumpster fire. 
    8. Amazing friends who check in and keep me laughing, and generally know just the balance to strike when things are hard. 
    9. My parents’ beach house, and that it’s large enough we have our own room always, it’s a great reprieve. 
    10. Being lucky to own our home, have reliable cars, and generally not be stressed in this wild financial market. 
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