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HCG doubling time

allysonjeanallysonjean member
in 1st Trimester
My first draw at 13dpo was 193 and my second at 15dpo was 414- that’s a doubling time of 43 hours. My concern though is that it appears that my levels had to nearly triple to get up to 193 by 13dpo and now it appears that it has slowed down to slightly more than doubling. Should I be concerned? 
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Re: HCG doubling time

  • capnjackharknesscapnjackharkness member
    The only thing you can do is keep getting betas every 48 hours and seeing if the numbers continue to double.  It's doubling right now, and that is good news.  You need to stay calm and discuss any concerns you have beyond that with your doctor.
    #BitterHagPartyOf1

    Melody Pond GIF
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  • inthewoods23inthewoods23 member
    I'm confused.... your first blood draw was 193, but your numbers had to triple to get to 193 by 13dpo? How would you know that if it was your first blood draw?

    Anyway, my understanding is that doubling times will decrease as you get further along. It's normal.
    *TW* History
    TTC #1 since 7.2017
    Dx: low morph (1%), ANA positive, low decidualization score, high TSH and testosterone, histone antibodies

    IUI #1-3 | all BFN
    IVF #1 | 6.11.19 | 24R, 17M, 15F, 6B, PGT-A tested - 5 normal, 3 girls & 2 boys
    FET #1 | 9.10.19 | BFN "I know you, but we've never met. I'm with you, but I don't know your name"
    RPL, Receptiva, & ERA testing | all normal/negative, recommended going on gluten and dairy free diet for next FET
    FET #2 | 3.31.20 | Opted to cancelled due to pandemic, continued diet and tried naturally over the summer
    2nd Opinion with another RE | 8.20.20 | Not immune to measles (received 1 dose); SA results similar to 2 years ago; decided to move forward with FET #2 redo at start of next cycle
    Surprise natural BFP! | 9.22.20 | MC 10.23.20 at 8 weeks
    TTCAL naturally | starting 11.22.20

    Initial consultation with Reproductive Immunologist | 9.14.21
    Decidualization score biopsy | 10.1.21 | abnormal - low score of 1; endometrial scratch recommended and progesterone supplementation
    Saline sono | 10.15.21 | normal
    Bloodwork | 10.21.21 | high TSH, high testosterone, positive for anti-nuclear antibodies and histone antibodies, high protein S, multiple genetic mutations
    BFP! | 11.3.21 | EDD 7.14.22 B) | biopsy provided same effect as endometrial scratch; added supplemental progesterone and estrogen, prednisone, levothyroxine, and MTX Support to maintain pregnancy
    DS born 7.19.22 after induction


    TTC #2 begins 6.2023
    Consultation with RI | 6.6.23
    Saline sono, endometritis biopsy, skin & eye check | all normal
    Labs | high TSH, Factor XIII mutation, high %CD56
    Follow up | 8.8.23 | prescribed metformin, prednisone, plaquenil, and levothyroxine
    Repeat labs after 3 weeks on meds
    Follow up | 11.9.23 | Green light!, increase in prednisone, added lovenox
    Repeat labs in 8 weeks
    Follow up | 1.16.24 | Green light continues
    TTC ended due to filing divorce

    **New relationship starting May 2024**

    Surprise BFP!! | 9.7.25 | EDD 5.11.26
    Its Gonna Be May GIFs Tenor
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  • ladyp0tterladyp0tter member
    Normal is still 48-72hrs up to about 1200 HCG. Then it slows to 72-96hrs. You are well within that range.
    Me: 45yo, DH: 47yo
    3 Daughters (singleton @27yo, ID  Di/Di Twins @34yo)
    Protein S Deficiency (Blood Clotting Disorder), MTHFR & VIT D issue 
    5 MC's:  Blighted Ovum-D&C @ 9wks;  Natural MC @ 7wks; Blighted Ovum-D&C @ 9wks; MC boy-D&C @ 9wks & Chem PG in 2019
    Tubes were tied after my Twins (and now I am old). Remarried and want to give my DH a baby!

    IVF#1 OE June 2019 - ER 6/15/19, 24R, 21M, 20F, 7 6DBlasts Frozen for PGS Testing,
    RESULTS of PGS 4 abnormal girls,  2 abnormal boys, 1 indeterminate girl
    FET#1 OE August 23, 2019 (transferring 1 indeterminate girl & 1 abnormal boy) - BFN
    IVF#2 November 15, 2019 - ER 9R, 9M, 6F, 2 5dBlasts (fresh transfer) and 1 6DBlast frozen for PGS Testing,
    FRESH Transfer: November 20, 2019, 2 5-day blasts transferred!! 
    BFP 8dp5dt on 11/27 - 12/2 on FRER, BETA #1 12/2 - 11.93. BETA #2 12/4: 4.41 ~CHEMICAL PG
    ******************Starting Donor Process
    June 2020: Egg Donor Cycle and Fresh Transfer of 1 embryo in Czech Republic - CANCELLED DUE TO COVID19
    October 2020.  Split Cycle at UFC with a friend (Andrea) I met on the Bump who was also supposed to go to Prague too  
    DE Retrieval 9/26/2020, 26R, 24M, 12 split Cycle, 9 Fertilized + 1 "questionable", PRAYING FOR AT LEAST 5 BLASTS
    10/1/2020: 4 5DBlasts (AA, BB, BC, BC), 10/2/2020: 3 6DBlasts (BB, BB, BC) FOR A TOTAL OF: 7 BLASTS!! THANK YOU GOD!!
    PGS RESULTS: 5 NORMALS! DAY 5: AA BOY, BB GIRL, BC BOY / DAY 6: BB GIRL, BC GIRL
    DE FET October 29, 2020 - CANCELED DUE TO FLUID IN LINING
    DE FET November 16th, 2020 (transferring an PGS normal Hatching AA Boy)
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  • steph-annsteph-ann member
    Hi! I am 5 weeks tomorrow. I asked yesterday for a beta test to check levels because I had a miscarriage in August. My HCG is at 11,669. The nurse said that would make me like 7/8 weeks pregnant. I don’t really know much of anything about levels and the doc never called me back. I had my period start Dec 26 and we were using protection up until Jan 4th-ish. Anyone have any knowledge about this? Now of course my mind goes to Twins... and it’s the weekend so I won’t speak to a doctor until next week.
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  • BuckeyeNut05BuckeyeNut05 member
    http://www.betabase.info/

    HCG levels vary wildly. The only way to know for sure is when you go for your u/s. Good luck. 
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  • stormageddon-darklordofallstormageddon-darklordofall member
    @stephaniewagner The point of having a HCG Beta draw is that you're supposed to get a second one 48 hours later.  If they double, you are good.  If they don't double, you are most likely headed towards MC or it could indicate other problems.  If the number more than doubles (like astronomically so), then it could indicate an ectopic.  One number alone is only good enough to tell you that it reached a certain level, as @BuckeyeNut05
     pointed out, HCG levels vary wildly.  You have a very good number though, so chances are they may just tell you to wait until your first appointment/ultrasound.
    *TW All the Loss* #BitterHagPartyOf1

    October 2015 - 1st MC.  7-8 weeks along. Suspected molar PG, but luckily just a MMC.

    June 2016 - 2nd MC: 4-5 weeks CP

    September 2016 - 3rd MC: 4-5 weeks CP

    RE 1: ALL the testing - 'unexplained'  "Yinz can do IVF or try on your own"

    Feb 2017 - 4th MC: 6 weeks

    RE 2: More tests. Still 'unexplained.'  Called fat for an entire hour-long appointment, cried a lot

    Feb 2019 - 5th MC: 6-7 weeks

    IUD - March 2019-March 2023

    RE 3:  Repeat all the tests. Hoping to try IVF.

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  • steph-annsteph-ann member
    Thank you! Yes, they just told me to wait until my first ultrasound. They can’t justify more testing without having spotting or other troubling symptoms. My pregnancy symptoms have hit pretty heavy early this time so thinking everything is ok. I won’t know until March 1. 
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