Trouble TTC

Intro/thoughts

Hello We've been trying for over a year and I finally went in for my follow-up appointment. I have one blocked Fallopian tube and low progesterone. He has low percentage of normal sperm morphology and high concentrations of round cells. The Dr. Said that he recommends HMG IUI or IVF. He said his Sperm isn't the problem. I asked why not treat the Progesterone since I still have one tube and we got pregnant once and he said that it wouldnt fix the main issue. I also asked about looking further at my blocked tube and he said he doesn't recommend the procedure. What do you think? I've gone ahead and scheduled an appointment with another RE to get a second opinion.  Thanks for your input

Re: Intro/thoughts

  • Welcome!
    I think getting a second opinion is a good idea.
    Was your RE concerned about the "round cells" in the SA? I think a large number of white blood cells could mean infection, which if treated might increase your chances significantly. 

    A low progesterone suggests that you are not ovulating on your own, so your RE is saying, rather than just give you progesterone, you should be on medications to stimulate follicle growth and release. 

    Have you been temping? That would help you understand your cycle better and see if you are ovulating. 

    Good luck, I hope the second opinion doctor can shed some light on the situation for you. 

    Me 34 DH 36 Married since July 2010 
    MFI (High DNA Fragmentation) & Mild endometriosis
    TTC #1 since June 2015 
    Aug 2016 - May 2017  6 IUI's with letrozole - BFN
    April 2017 - laparoscopy to remove mild endo
    June 2017 - Mini IVF letrozole 12.5mg, Gonal-F 75IU - Cancelled early ovulation, no eggs retrieved. 
    Aug/Sept 2017 - Mini IVF letrozole 12.5mg, Gonal-F 75IU, cetrotide - 13 eggs retrieved, 11 mature
    5 eggs ICSI'd 6 eggs frozen - 1 day 5 blast transfered, 2 expanded blast frozen - BFP!
    May 2018 - Baby girl born - Our Joy

    TTC #2 since July 2019
    July 2019 - FET - BFN
    Jan 2020 - FET - canceled due to family health issues
    Mar 2020 - FET - low beta - chemical pregnancy
    July 2020 - ICSI'd remaining 6 eggs - 3 fertilized - 2 survived to early blast stage, transfered both - Chemical Pregnancy


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  • Hello and welcome, this is a great place of support! I can't speak to your specific issues but a 2nd opinion is a great idea
    TTC since May 2013
    Mild PCOS, Compound Heterozygous MTHFR
    No Folic acid/pharmaceuticals/supplements (too many to list- private message me if interested), IVIL infusion
  • Msjen11Msjen11 member
    Welcome!
    I think getting a second opinion is a good idea.
    Was your RE concerned about the "round cells" in the SA? I think a large number of white blood cells could mean infection, which if treated might increase your chances significantly. 

    A low progesterone suggests that you are not ovulating on your own, so your RE is saying, rather than just give you progesterone, you should be on medications to stimulate follicle growth and release. 

    Have you been temping? That would help you understand your cycle better and see if you are ovulating. 

    Good luck, I hope the second opinion doctor can shed some light on the situation for you. 
    Thanks he said he wasn't concerned about the round cells. Are you talking about his or my white cells? I bought a basal thermometer and plan on starting my next cycle which is real soon. My progesterone was low at 3.6ng/ml. Thanks for your response and well wishes. I scheduled my second consultation. 
  • Msjen11 said:
    Thanks he said he wasn't concerned about the round cells. Are you talking about his or my white cells? I bought a basal thermometer and plan on starting my next cycle which is real soon. My progesterone was low at 3.6ng/ml. Thanks for your response and well wishes. I scheduled my second consultation. 
    His white cells, in the SA. I'm not sure what else round cells could be, but maybe your doctor could clarify that.

    A lot of us use fertility friend as our BBT tracking app; it has a lot of great tutorials to get you started. 
    Good luck with you second visit!

    Me 34 DH 36 Married since July 2010 
    MFI (High DNA Fragmentation) & Mild endometriosis
    TTC #1 since June 2015 
    Aug 2016 - May 2017  6 IUI's with letrozole - BFN
    April 2017 - laparoscopy to remove mild endo
    June 2017 - Mini IVF letrozole 12.5mg, Gonal-F 75IU - Cancelled early ovulation, no eggs retrieved. 
    Aug/Sept 2017 - Mini IVF letrozole 12.5mg, Gonal-F 75IU, cetrotide - 13 eggs retrieved, 11 mature
    5 eggs ICSI'd 6 eggs frozen - 1 day 5 blast transfered, 2 expanded blast frozen - BFP!
    May 2018 - Baby girl born - Our Joy

    TTC #2 since July 2019
    July 2019 - FET - BFN
    Jan 2020 - FET - canceled due to family health issues
    Mar 2020 - FET - low beta - chemical pregnancy
    July 2020 - ICSI'd remaining 6 eggs - 3 fertilized - 2 survived to early blast stage, transfered both - Chemical Pregnancy


  • Msjen11Msjen11 member
    Msjen11 said:
    Thanks he said he wasn't concerned about the round cells. Are you talking about his or my white cells? I bought a basal thermometer and plan on starting my next cycle which is real soon. My progesterone was low at 3.6ng/ml. Thanks for your response and well wishes. I scheduled my second consultation. 
    His white cells, in the SA. I'm not sure what else round cells could be, but maybe your doctor could clarify that.

    A lot of us use fertility friend as our BBT tracking app; it has a lot of great tutorials to get you started. 
    Good luck with you second visit!
    Sorry I should have clarified that it is his morphology. I set-up FF after reading about it on another board. Thanks agaj
  • Hello and welcome.  I have a few thoughts (not a doctor, just things I've observed from my own journey).  First of all, I think you're totally on point to seek a second opinion if you are not clicking with this doctor (or want to make sure that you are).  You should feel comfortable asking your doctor all of these questions, and your doctor should explain them in a way that allows you to be comfortable with the choices you'll be making.  Second, on the morphology, my understanding is there is some dispute about how much it really affects fertility--some REs think it's an issue, others are less worried.  Third, the injectables could help with ovulation, assuming that the progesterone levels are a sign of an ovulation issue.  And last, IUI still requires tube involvement, so it's not like this doctor is writing off anything that would require that (not sure if that's what you're wondering, or if you're just saying why not try to get both unblocked generally).  If tubes were both blocked, IUI would be off the table, I believe.  

    Good luck to you!
    About me:
    /loss mentioned/
    TTC#1 July 2014
    dx: MFI (morphology)
    IUI #1 w/Clomid + Ovidrel Sept. 2015 ~ BFN
    IUI #2 w/Clomid + Ovidrel Halloween 2015 ~ BFN
    IUI #3 w/Clomid + Ovidrel Thanksgiving 2015 ~ BFP!!
    hb 146 bpm at 7w5d
    1/28/16 ~ began to say goodbye to our beautiful baby at 11w 
    d&c, followed by cytotec
    TTCAL April 2016
    IUI #4 w/Clomid + Ovidrel Apr. 2016 ~ BFN
    IUI #5 w/Clomid + Ovidrel ~ CP
    IUI#6 w/Clomid + Ovidrel ~ BFN
  • Msjen11Msjen11 member
    Hello and welcome.  I have a few thoughts (not a doctor, just things I've observed from my own journey).  First of all, I think you're totally on point to seek a second opinion if you are not clicking with this doctor (or want to make sure that you are).  You should feel comfortable asking your doctor all of these questions, and your doctor should explain them in a way that allows you to be comfortable with the choices you'll be making.  Second, on the morphology, my understanding is there is some dispute about how much it really affects fertility--some REs think it's an issue, others are less worried.  Third, the injectables could help with ovulation, assuming that the progesterone levels are a sign of an ovulation issue.  And last, IUI still requires tube involvement, so it's not like this doctor is writing off anything that would require that (not sure if that's what you're wondering, or if you're just saying why not try to get both unblocked generally).  If tubes were both blocked, IUI would be off the table, I believe.  

    Good luck to you!
    My concern is that I would like to proceed with addressing progesterone and trying naturally if at all possible for a few cycles. Thanks!
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