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High-Risk Pregnancy
ALC08
member
Mthfr
ALC08
member
Has anyone been diagnosed with mthfr and been prescribed high dose folic acid and went on to have a healthy pregnancy??
I miscarried twice in 8 months and was recently diagnosed. After doing some research, i'm concerned the folic acid may not solve the problem. Really don't want to go through this again.
I miscarried twice in 8 months and was recently diagnosed. After doing some research, i'm concerned the folic acid may not solve the problem. Really don't want to go through this again.
Best Answers
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PlainJane8350 member
I was and I'm currently 27 weeks. They have me Folgard, then I switched to Fab Tab and I take one pill, twice a day.
Do you have access to a geneticist at your doctor's office?
I've read things that say it needs to be folate, not folic acid, but a fertility specialist prescribed it to me while we were investigating my loss and my current doctor, a perinatologist, just refilled it last week. - Loading the player...
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Thank you and I'm so sorry for your losses. Did they find a clotting issue, hence the aspirin?
Fab Tab is just the genetic version of Folgard, although it's the same price so no clue. They gave me a choice of three and Folgard was the only one my pharmacy carried at the time. I started taking it as soon as they diagnosed me, before we started trying again, and felt a difference in my energy level/mood immediately. I see a high risk specialist, too. Someone there should be able to talk to you about it. I go back on July 10th and I'll ask, I've wondered about it anyway.
Re: Mthfr
Plainjane19792001@gmail.com
I would ask if you have a clotting issue as they usually advise against aspirin during pregnancy unless you do. Baby aspirin is so small that it may not pose a risk and it is a very common recommendation.
Did they check your progesterone and your husband's sperm? Did y'all do any testing on the babies themselves?
B12= 5000
B6= 5000
1 baby aspirin
40mg lovenox
Having one single bad copy of both I was originally prescribed folgard (synthetic folic acid) and lovenox (blood thinner). I questioned the effectiveness of synthetic folic acid on folgard bc if I can't absorb it- what's the point? My dr said bc I have one good and one bad copy I can still absorb some so a higher dose tries to get more through. I also chose to seek out a organic prenatal (found simply at gnc). The organic prenatal has organic folate (in the natural form we can absorb and not synthetic). The lovenox blood thinner was to prevent blood clots and help absorption of the embryo to implant and those injections stated at first positive pregnancy test.
THEN! Then I went to a mfm(high risk ob) to monitor once pregnant. He literally told me that reproductive endocrinologists (fertility drs) do a lot of voodoo and it's not supported by research. I was floored by this and stated doing a lot of research. Turns out he was right! There is more research now to support not treating MTHFR (unless you have homozygous-2 bad copies of one gene). The American college of gynecology (ACOG) medical journal outlines the unnecessary use of lovenox in pregnancy from unnecessary MTHFR testing. They clearly recommend stopping lovenox unless you have 2 bad copies of MTHFR (the one that affects blood clotting) or if you have had blood clots previously. I only have one bad copy and no personal history of blood clots so I chose to go off lovenox bc it does have risk factors during pregnancy for the baby. I also chose to continue with my organic prenatal and stop folgard at my mfm's recommendation bc there is no research to support that high doses of synthetic folic acid help retain pregnancies. I don't like taking medication I don't need, especially while pregnant. I am now 30 weeks, only taking organic prenatal and baby aspirin (bc I had preeclampsia with last pregnancy) and have no issues.
I will also add- the hematologist I saw while taking lovenox told me she could go either way having a pregnant woman with one bad copy. She would allow me to take it if my RE wanted it but it wasn't necessary. She said in her practice ppl who have 2 bad copies of MTHFR that affects blood clotting having already been seen bc they have had a blood clot in their personal history. Those that have one bad copy are usually unaffected. Her recommendation was to go off lovenox after first 12 weeks (bc I was already that far and it CAN help with implantation in early pregnancy). So I followed her recommendation due to fetal risk factors from lovenox and the delivery complications of being on a blood thinner.
It's sooo much. Try to do your own research. If you have any questions feel free to message me!
Glad you got a little bit more info! I called the specialist who diagnosed me and talked to his receptionist. I told her why I was calling, because I've read different things online, and she advised me to trust my doctor...not stuff I read online. I do trust him so I'm going to take her advice, plus the folic acid seems to be working for me, but everyone should do what they feel is best for them. ☺
As others had mentioned I am on Folgard. I was also immediately at 3w6d put on injectable Heparin 2X's a day.
No baby asprin. I'm learning too.
Are you comfortable taking Folgard? I keep having all these MTHFR groups (found online and FB) telling me its DANGEROUS
If so then why did my high risk OB prescribe it?
I've had 2 losses and I'd love for this one to stick. I am also on twice a day Heparin.
Thanks
Why do these groups claim that it's "dangerous?" I've heard people say that they think taking the form that Folgard comes in is pointless, but I've never heard that it's dangerous. Are the people in this group fertility specialists, perinatologist, etc? I don't even feel like regular OB's understand conditions like this because when a patient has one, they usually refer them out to specialists. I'm sure people who work at Vitamin Shoppe or are chiropractors or just have a passion for health and fitness know some things, but when it comes to my pregnancy I trust the experts now. I did do my own research initially, though!
With that said, I'm so sorry for your losses and am excited for your current pregnancy. It's so scary, but super exciting at the same time. Did the pin point the cause of both losses to MTHFR? I can only tell you how I feel about it, but here's my e-mail if you just want an MTHFR pregnancy buddy!
Plainjane19792001@gmail.com
Hey Plainjane8350, I in boxed you to see how things are going! What I have read about folic acid is that the excess we can"t process builds up in our bodies and can cause several health issues. Not necessarily pregnancy related or anything that affects baby. I am transferring my records to my family dr to get his input.
Plainjane78 sorry for your losses, I have had two as well. Hoping you get a different outcome this time! Twice is more than enough for us to endure this pain. I know some have to more than that. I am hoping to be pregnant again soon, soon. Is the heparin due to another issue or MTHFR? Just wondering why both if only one gene was affected. If I understand correctly mine is from two separate genes. I am just learning about all of this.
I have also read about possible connection between MTHFR and autism, Have either of you come across anything. not sure that it causes it but some stat about a high percentage of ppl with MTHFR (may have been compound heter) also being autistic? More worries..
Which 2 genes do you have effected? Mine is one C677t, the most common and the one with less issues. I don't know what to say about the whole NO folic acid thing .... I take folgard, which has folic acid but I need to to keep my homocycteine levels at bay (higher the level more risk of heart attack and stroke, normal is a 7 or lower, I was a 15!)
I'm not worried about the effects of autism and MTHFR .. there are like a million conditions they link to autism .. it is what it is at this point, ya know?
Don't be afraid, keep trying! I hope you get your rainbow soon also!
Since you have MTHFR you might want to look into being put on blood thinners (either Heparin or Lovenox) since those with MTHFR are VERY prone to blood clots.
That is why I lost my first 2 pregnancies. I didn't know and the placenta clotted
Plainjane19792001@gmail.com