Comprehensive Chromosome Screening

Drumski · August 2015

Anyone have this done? Our RE highly suggested we test our embryos. We are nervous on so many levels. It is an out of pocket expense (5,400) and we want just don't know much about this testing.

Frenchteachermama · August 2015

Welcome! Actually quite a few women here have, and have had great success...well actually they are not "here" anymore since we ask that people move over to PAIF or SAIF after they have success. I am going to page @fuzzbumble and she can PM you about the process.

Good luck.

Drumski · August 2015

Thanks.

Davie813 · August 2015

I just had it done (I got my results on Monday), so I obviously can't tell you yet whether it was worth it. If there's anything I can answer from so early in the process, though, I'll give it a try.

Drumski · August 2015

Thanks! @davie813 I'm just scared. I'm scared they are going to come back and say that none of my eggs are viable. After the test, does the lab give you any updates? How long does it take to get results? Did you do it on a fresh or frozen embryos?

ellebelle2384 · August 2015

I just had PGS testing (which is pretty much the same as CCS, just uses a different method) done on our frosties. The RE lab grew as many of my embryos to day 5 and then took biopsies and did a freeze all. The samples were then all sent out to an outside lab and it took about 4-5 days to get results back. Like you I was scared of getting results saying all our embryos were abnormal (since the whole reason we are doing IVF with PGS is that we have recurrent losses believed to be from aneuploidy in my eggs). After 4 consecutive losses and 5 overall I was not willing to do a transfer without knowing that we were transferring a normal embryo. Thankfully we have 6 normal embryos and are gearing up for a September FET. The ladies on PAIF and SAIF will be able to tell you if it was worth it for them.

Drumski · August 2015

I'm so happy for you. I wish you all the best and a positive pregnancy test! @ellebelle

Davie813 · August 2015

I had mine tested after 2 losses in a row (and I'm 41), so I was really afraid they wouldn't find any normal ones, either.

I had embryos batched from two cycles tested. I had 4 untested frozen blasts leftover from a previous cycle, then completed a new cycle and added the fresh embryos to the batch. It's better to have them biopsied fresh, because then they don't have to be re-thawed and re-frozen, but they can biopsy and test frozen embryos. I can't really advise you on the timing, because we sent ours to the lab before we were sure we wanted to have them tested this cycle (we were considering another round of IVF in order to have more to work with). Once I gave them the go-ahead, though, I had results within a few hours. The genetics lab won't give you any updates, if that's what you mean. They communicate the results directly to your RE.

I should be transferring in September, so I obviously don't know if the process "worked" for me, but I can say that the normal embryos were definitely not the ones with the highest grades. If I'd gone without the testing and just had them transferred based on their quality as determined by appearance, I definitely would have had a few more losses before (hopefully) being successful.

Good luck!

Drumski · August 2015

We signed all the forms and paid today. My RE said I need to use my frozen embryos before I make more. Hopefully we don't need to make anymore! Wishing you lots of luck!!!

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