Waiting for 5d transfer, worried about prog/estrogen.

Re: Waiting for 5d transfer, worried about prog/estrogen.

• jnissa member

  August 2015

  Completely common. Pretty much every cycle includes progesterone. Estrace I think depends on your baseline and your RE.

  
  

  Every body is different, but I can tell you that the only med that was ever really hard for me to tolerate was the progesterone. Awful. And *when* you get pregnant they'll want you on it for almost the full first trimester. I had nausea, fatigue, weight gain, irritability, the entire scenario. But again, every body is different and the reason for the progesterone is important (to maintain uterine lining). 

  Me: 41, DH 38, Diagnosis DOR

  Started TTC 12/2013

  First Trip to RE: 11/2014

  IVF Round 1: 2/2014 - BFP

  DD Born 11/9/2014

  TTC a Sibling Started 5/2015

  First IVF Round 8/15 - BFN

  Taking a break to go on vacation + enjoy the holidays before FET and/or another IVF round in 2016!

  
  

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• bookworm40 member

  August 2015

  What kind of progesterone are you on? I've been on crinone 2x a day for 13 days now and the only thing I've had is irritability and sore breasts. I'm also on estrogen 1x daily and have noticed nothing from that. It's important to be on it so it's one of those things that even if we hate taking it, your body can't sustain an early pregnancy without the right levels.

  Me: 40  

  TTC #1: 3 years

  Me: Type II Diabetic

  Started with RE 11/2014
  

  Going through IUI with Donor Sperm

  
  
  

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• MelenaZ member

  August 2015 edited August 2015

  I am on endometrin (100mg) vaginal suppositories 3 times a day. Estrace 2mg 2x day. I have been super bloated, constipated, sore breast, and still a lot of fatigue. I blame it al on progesterone. Hopefully I won't have to be on it for a long time.

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• riveridgional member

  August 2015

  I've never taken progesterone suppositories buy I have taken it orally and it only caused me random bouts of dizziness. I took Estrace vaginally and that one really did cause irritability and mood swings. Oh, and don't forget the lovely blue discharge. Your protocol sounds like what my doctor prescribes for his IVF patients.

  Married to DH 10/6/12

  TTC since 5/14

  Unexplained with (controlled) hypothyroidism and suspected ovulatory dysfunction (but, I do ovulate on my own)

  Clomid 50 mg 3/15 (unmonitored) - BFN

  Clomid 50 mg + metformin 4/15 (unmonitored) - BFN 

  First RE appt. 5/15; Natural cycle 5/15 monitored with 2 mature follicles and Pregnyl Trigger (full dose) + prometrium - BFN

  6/15 HSG - clear tubes & normal uterus; great PCT test results

  TI - 100 mg Clomid + prometrium (AM & PM) + vaginal estrace (AM & PM) 6-7/15 (monitored) --> no additional response and thinned lining - BFN

  TI - Injectables (follistim + Gonal-F, Ganirelix, & 1/2 dose Pregnyl) + prometrium (AM & PM) 9/15 --> 3-7 mature follicles (3 definites and 4+ that could have matured due to trigger) @ O -->BFN + 5 large cysts

  BC for 2 weeks due to cysts
  

  TI - Injectables (Gonal-F, Ganirelix & full dose Pregnyl) + prometrium (AM & PM) 10/15 --> 1 mature follicle --> BFN 

  TI - Last attempt at injectables (Gonal-F, Ganirelix & 1/2 dose Pregnyl) + crinone (AM only) + vaginal estrace (AM & PM) 11/15 --> 3-4 mature follicles --> BFP!! 11/27/15 @ 13dpo (shockingly, actually waited until then to test)

  
  

  Beta #1 @ 16dpo (11/30/15) = 1,075

  Beta #2 @ 19dpo (12/3/15) = 3,150

  One baby: Saw heartbeat @ 5w5d (114 bpm; baby measuring 2.3mm)

  
  

  "Great Things are Happening"

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• krbjoy member

  August 2015

  I'm on progesterone suppositories, 2 morning and 2 evening. Yellow discharge from the capsule...awesome... Also on two Estradiol patches changed every 3 days. The progesterone has me bloated, gassy, constipated and tired. I'm cramping too which I attribute to the progesterone. It could be the patches though, symptoms also include stomach issues. The patches have me all out of it. I read a side effect was problems with speech and thought, wow really? Well, yeah, it's true. Not extreme, just find myself fumbling my words. Fun Fun Fun.

  Married for 4 years. TTC for 3.

  Me: 38 DH: 39

  DX: Unexplained Infertility; found a few fibroids this time around during SIS

  
  

  March 2012: Clomid for 3 cycles  3 BFNs

  Sept. 2013: started injectables (Follistim, Ovidrel Trigger) IUI BFN

  
  

  May 2015: New RE. Going IVF. Tests, Tests, Tests 

  July 2015: Microdose Lupron 20u am & pm, Follistim 150iu 75iu am, Menapur 150iu 75iu pm

  Triggered 8/4 ER 8/6 ET 8/11 2 beautiful blastocysts; 2WW

  8/19 hpt BFP! Beta 8/25: 482

  2nd Beta 9/1......3707

  U/S 9/21: 1 beautiful little gummy bear

  
  

  
  

  
  

  

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• jnissa member

  August 2015

  Actual quote from my nurse today, "I mean, there's no such thing as progesterone without fatigue and some crazy."

  
  

  I love her. But keep some humor about it like she did, I think is good advice. Extra hormones are never, ever fun (unless you're estrogen priming). 

  Me: 41, DH 38, Diagnosis DOR

  Started TTC 12/2013

  First Trip to RE: 11/2014

  IVF Round 1: 2/2014 - BFP

  DD Born 11/9/2014

  TTC a Sibling Started 5/2015

  First IVF Round 8/15 - BFN

  Taking a break to go on vacation + enjoy the holidays before FET and/or another IVF round in 2016!

  
  

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• przemosbabe member

  August 2015

  That dosage is perfectly normal and fine, those meds are what you would be making in your natural cycle too so it's nothing to worry about.

  

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• MelenaZ member

  August 2015

  Thanks ladies. I am feeling much more comfortable with taking the hormones now. I just feel like a walking pharmacy. I never take meds. So going from nothing to my hormones, aspirin, abx from ER, n vitamin, I am constantly sticking some medication in me. But that's ok. Work towards the goal!! :x :x

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