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Injectible IUI cycle ?

deelopi9deelopi9 member
in Trouble TTC
Hi ladies...

For you ladies who had already completed an Injectible IUI cycle, how were your side effects starting on 75IU? I'm expecting bloating. I want to prepare myself and DH :)

Injects are going to fall before/after Thanksgiving.  He may up my meds depending on how I respond. RE mentioned the injects will be between 7-10 days.

image
3T January Siggy Challenge: New Years Resolutions 
TTC since 10/2010 (Rhythm method since 2007)
Me (33) Sept 2012 - DX Low ovulation/progesterone, Luteal Phase Defect. HSG 5/2012: both tubes are open, cervix and lining look good;
September 2014 DX Hashimoto's; November 2014: PCOS IR
***
DH (37) Sept 2012 SA Normal; October 2014 Mild MFI count 42 Million, Motility 36%, Morphology 2%. Clomid 50mg,
***
2004 Cyrosurgery, LEEP
May 2012 - HSG Clear; June 2012 - Appointment with RE
July 2012 - October 2012 - Clomid 50mg W/ TI & Progesterone 3 mature follicles- BFN
January 2013 IUI #1 (900,000 post wash) Clomid 50mg, TI & Progesterone 2 mature follicles - BFN
February 2013 IUI #2 (1.3 Mil post wash) Clomid 50mg, TI & Progesterone 4 mature follicles - BFN
March 2013 IUI #1-3 (2.5 mil post wash) Clomid 50mg, Baby Aspirin (lining thinned) TI & Progesterone - 2 mature follicles BFN
April 2013 Benched due to cyst, May 2013 WTF appointment
June 2013 DH SA mild MFI break for 2 months to re-test; August 2013 - DH SA 36 Mil count, 36% Motility, Morp 2%
September - December 2013 - Mental sanity Break
January 2014 - IUI #4 switches to natural due to scheduling conflict Femara TI & Progesterone - 1 mature follicle - BFN
May 2014-June 2014 - DH Appointment w/ Urologist to check Bi-lateral Varicocele; 2nd opinion w/ another urologist - bi-lateral varicocele dx is slight no surgery
July 2014 DH starts clomid 25mg daily SA 53.8 Mil count, Motility 37%, Morph 3%;
September 2014 DH Repeat SA after being on clomid for 3 months 42 Mil Count, Motility 36%, Morph 2%
October 2014 Me: Hashimoto's DX, DH taken off clomid;November 2014 Me: new RE PCOS IR Diagnosis
December 2014: IUI #4 Follitism 75iu 7 days, TI, IUI & Progesterone, BFMFN
January 2015: IUI #5 Gonal-F 75iu 7 days, TI, IUI & Progesterone, Another BFMFN onto IUI #6
   image

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Re: Injectible IUI cycle ?

  • RachaeleighRachaeleigh member
    I started at 150iu and didn't have many side effects. There was definitely some fullness and tenderness when Oing and right after, but that was due to multiple follicles, not necessarily the medication

    4 Losses (2003, 2008, Apr 2012, & Oct 2012)
    All RPL and IF testing with multiple REs = normal

    5 IUIs = BFN

    All AL are welcome
    Image and video hosting by TinyPic

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  • BunnyBerryBunnyBerry member
    Glad you asked this question, I was wondering the same thing!

    Our RE said that women who had SEs on Femara tend not to have them on injects. Hopefully that's true. :)
    January 3T Siggy Challenge - New Year's Resolutions
    image
    imageimage

    Me (29), DH (30) TTC actively 54 55+ cycles | All BFNs
    MFI (low everything) | Endo Stage 1 & Stenotic Cervix (treated) | PCO
    Married - July 2008 | Started TTC - Jan 2009 | RE Visit #1 - Mar 2014 
    IUI #1 ICI #1 - June | IUI #1.1 Laparoscopy - Aug
    IUIs #1.2, 2, 3 - Sept, Oct, Nov (Letrozole) - BFNs 
    IUI #4 - Dec (Bravelle) | IUI #5 - Dec/Jan (Bravelle) - 5 follies + TI - BFNs
    IUI #5.1 - Jan (Bravelle) Cancelled 
    Planning to start IVF in March!
    ***All Welcome***
    Report Reply
  • southernyankeegirlsouthernyankeegirl member
    edited November 2014
    **** Grad Warning ****



    I hope it's okay to post (mobile so can't see siggies). For my Follistim-only IUI, I had fewer symptoms than Femara & Follistim hybrid cycles, with much better results. I only noticed some ovarian soreness around O, and my lining was significantly thicker, I had 7 follicles in the running at one point that went to 2-3 mature at ovulation (compared to 1-2 even in contention with Femara & Follistim hybrid cycles), and of course (and most importantly) it was a successful cycle.

    If I ever have to do this all again, I am jumping right to Follistim IUI. It's definitely what worked best for us! I hope it works for you, too!!!!!
    ************************SIGGY WARNING***********************

    Me: 29      DH:  32
    Off birth control March 2012 - Actively trying Sept 2012-April 2014
    Unexplained Infertility
    BFP on May 5th after Follistim & IUI #3
    Ryan Henry - born 1/10/15, 7 lb 5 oz, 20 1/4 inches

    NTNP for a sibling starting March 2015
    Waiting on cycle to resume while EBF


    imageimage

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  • sweetball33sweetball33 member

    Thanks for asking about this @deelopi9!  I'm starting injects in January assuming this IUI is unsuccessful!  Met with RE yesterday to go over everything, and he did mention that most people have very few side effects when compared to clomid cycles (besides a little bloating).

     

    Good luck!

     Me: 30 ~ DH: 30
    Married: October 1, 2011
       TTC: since Jan 2013
    Diagnosis: Unexplained Infertility March 2014
    IUI 1 & 2 - Natural - BFN
    IUI 3 & 4-  50 mg Clomid+ Trigger = BFN
     IUI 5 & 6 50mg Clomid +Trigger + Crinone = BFFN
    Benched Dec 2014
    IUI 7 - gonal-f + trigger + Crinone = BFFN
     
     
     
     

     
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  • deelopi9deelopi9 member
    @sweetball33 thanks - hope this cycle is successful for you.

    @southernyankeegirl - absolutely, thank you so much for your feedback. With clomid I had more side effects than on femara. Glad it worked for you :)

    @Bunnyberry I hope so, the mood swings were getting pretty bad. I'll make sure to post any SE on the IUI check-ins :)

    @rainbowbridge14 @je11ybean85 @rachaeleigh thank you so much!
    image
    3T January Siggy Challenge: New Years Resolutions 
    TTC since 10/2010 (Rhythm method since 2007)
    Me (33) Sept 2012 - DX Low ovulation/progesterone, Luteal Phase Defect. HSG 5/2012: both tubes are open, cervix and lining look good;
    September 2014 DX Hashimoto's; November 2014: PCOS IR
    ***
    DH (37) Sept 2012 SA Normal; October 2014 Mild MFI count 42 Million, Motility 36%, Morphology 2%. Clomid 50mg,
    ***
    2004 Cyrosurgery, LEEP
    May 2012 - HSG Clear; June 2012 - Appointment with RE
    July 2012 - October 2012 - Clomid 50mg W/ TI & Progesterone 3 mature follicles- BFN
    January 2013 IUI #1 (900,000 post wash) Clomid 50mg, TI & Progesterone 2 mature follicles - BFN
    February 2013 IUI #2 (1.3 Mil post wash) Clomid 50mg, TI & Progesterone 4 mature follicles - BFN
    March 2013 IUI #1-3 (2.5 mil post wash) Clomid 50mg, Baby Aspirin (lining thinned) TI & Progesterone - 2 mature follicles BFN
    April 2013 Benched due to cyst, May 2013 WTF appointment
    June 2013 DH SA mild MFI break for 2 months to re-test; August 2013 - DH SA 36 Mil count, 36% Motility, Morp 2%
    September - December 2013 - Mental sanity Break
    January 2014 - IUI #4 switches to natural due to scheduling conflict Femara TI & Progesterone - 1 mature follicle - BFN
    May 2014-June 2014 - DH Appointment w/ Urologist to check Bi-lateral Varicocele; 2nd opinion w/ another urologist - bi-lateral varicocele dx is slight no surgery
    July 2014 DH starts clomid 25mg daily SA 53.8 Mil count, Motility 37%, Morph 3%;
    September 2014 DH Repeat SA after being on clomid for 3 months 42 Mil Count, Motility 36%, Morph 2%
    October 2014 Me: Hashimoto's DX, DH taken off clomid;    November 2014 Me: new RE PCOS IR Diagnosis
    December 2014: IUI #4 Follitism 75iu 7 days, TI, IUI & Progesterone, BFMFN
    January 2015: IUI #5     Gonal-F 75iu 7 days, TI, IUI & Progesterone, Another BFMFN onto IUI #6
       image

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  • l0v3l0v3 member
    I started low with 50iu and don't remember having any issues.

    The next cycle I started on 50iu and was bumped up to 75iu. That time I felt some tenderness and just an overall feeling like my ovaries were heavy. 

    The next cycle I started on 75iu right off the bat I didn't experience any problems.

    Good luck!! 
    Report Reply
  • ShaunteeShauntee member
    I started at 112.5iu and the first three nights I took it I was super sleepy afterwards. After that fourth dose I was fine and didn't have any side effects.
    This round I started with 150iu and no side effects. Good luck!
    Me-33 DH-36.
    Married 11/10 TTC 11/10
    06/11- diagnosed with PCOS 
    7/11- D&C and benched for a year 
    9/12-4/13-6 rounds of 50 mg Clomid- no sucess 
    6/13- new doc
    7/13-4/14- 6 more rounds of Clomid. 50 mg and then stepped up to 100mg- no success 
    5/14-7/14- took break waiting for new insurance 
    7/14-new insurance= new doc- actually a RE!!!! 
    7/14-HSG and blood test good-PCOS confirmed by new doc 
    10/14 looking forward to 1st IUI w/ Menopur. Blood Test= Negative
    11/14- IUI #2     w/ Menopur- Blood Test= Negative
    1/15- IUI # 3 w/     Menopur- Blood Test= Negative
    2/15- Self Benched this cycle
    3/15/15-Suprise BFP on natural cycle!!!! EDD-11/16/15

    Report Reply
  • deelopi9deelopi9 member
    @buttmonkey34 Same here, coming from someone who never has any PMS or mood swings, clomid was a nightmare.  
    image
    3T January Siggy Challenge: New Years Resolutions 
    TTC since 10/2010 (Rhythm method since 2007)
    Me (33) Sept 2012 - DX Low ovulation/progesterone, Luteal Phase Defect. HSG 5/2012: both tubes are open, cervix and lining look good;
    September 2014 DX Hashimoto's; November 2014: PCOS IR
    ***
    DH (37) Sept 2012 SA Normal; October 2014 Mild MFI count 42 Million, Motility 36%, Morphology 2%. Clomid 50mg,
    ***
    2004 Cyrosurgery, LEEP
    May 2012 - HSG Clear; June 2012 - Appointment with RE
    July 2012 - October 2012 - Clomid 50mg W/ TI & Progesterone 3 mature follicles- BFN
    January 2013 IUI #1 (900,000 post wash) Clomid 50mg, TI & Progesterone 2 mature follicles - BFN
    February 2013 IUI #2 (1.3 Mil post wash) Clomid 50mg, TI & Progesterone 4 mature follicles - BFN
    March 2013 IUI #1-3 (2.5 mil post wash) Clomid 50mg, Baby Aspirin (lining thinned) TI & Progesterone - 2 mature follicles BFN
    April 2013 Benched due to cyst, May 2013 WTF appointment
    June 2013 DH SA mild MFI break for 2 months to re-test; August 2013 - DH SA 36 Mil count, 36% Motility, Morp 2%
    September - December 2013 - Mental sanity Break
    January 2014 - IUI #4 switches to natural due to scheduling conflict Femara TI & Progesterone - 1 mature follicle - BFN
    May 2014-June 2014 - DH Appointment w/ Urologist to check Bi-lateral Varicocele; 2nd opinion w/ another urologist - bi-lateral varicocele dx is slight no surgery
    July 2014 DH starts clomid 25mg daily SA 53.8 Mil count, Motility 37%, Morph 3%;
    September 2014 DH Repeat SA after being on clomid for 3 months 42 Mil Count, Motility 36%, Morph 2%
    October 2014 Me: Hashimoto's DX, DH taken off clomid;    November 2014 Me: new RE PCOS IR Diagnosis
    December 2014: IUI #4 Follitism 75iu 7 days, TI, IUI & Progesterone, BFMFN
    January 2015: IUI #5     Gonal-F 75iu 7 days, TI, IUI & Progesterone, Another BFMFN onto IUI #6
       image

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  • LAUR8199LAUR8199 member
    I have had no side effects from Gonal-F.  Each cycle I started at 150 per day and was bumped up to 300 per day with no effects whatsoever.  I had so many side effects from Clomid (did one natural cycle) including sweats, abdominal pain and very large cyst formation.  I would definitely recommend foregoing the Clomid if you can. 

     

    WARNING LOSSES MENTIONED
    Me: 30, unexplained
    12/11: Not trying; missed three birth control pills- BFP; m/c at 6 weeks D&C 
    6/13 Clomid 50 mg: BFN; developed 7 cm cyst; benched
    12/13 Surprise BFP! M/C at 8 weeks, D&C
    IUI #1 (11/14) Gonal-F three days of 150 m.g. three days of 300 m.g.; Ovidiril on day 9=  follies 21, 16, 13 BFN;
    IUI #2 (11/14) Gonal-F three days of 150 m.g. three days of 300 m.g.; Ovidiril on day 9=  only three follies all 16

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  • RN1175RN1175 member
    I was on the maximum dose, 300iu, of Gonal-F for my first medicated cycle. I took it for 8 days and the only side effect I had was a headache. I looked it up and it is a very common side effect of this medication. I also felt some ovary fullness and pain around CD 10-12 right before I did my trigger shot. I have heard that Clomid has many, many side effects. I am happy that my RE didn't think it would do anything for me so I will not have to take it.

    Married Sept. 2012

    Me 39 MH 40

    DD# 1 10/23/02

    DD#2 06/11/13

    2 losses, one before DD#2 at 5 weeks, one after DD#2 at 4.5 weeks

    TTC #3

    10/15/14 Consultation with RE

    Nov & Dec '14 IUI BFN & 1 cancelled d/t early O

    Jan 15 Consultations with 2 new RE's for different opinions for possible IVF with DE

    Jan '15 Starting the process for Foster to adopt!

     

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  • lebradfordlebradford member
    On 75iu I barely had any side-effects. I think, at most, I had a couple of headaches. It was significantly easier than a Clomid cycle in terms of how I felt. 
    **siggy warning**  **everyone welcome**

    ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
    DS- 11.07.02
    DSS- 6.26.04
    Married- 6.29.13
    TTC Again- Sept. 2013
    ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
    Test Results/Diagnosis- HSG & SA totally normal
    DX: 3/2014 Prolactinoma/Hyperprolactinemia- Started cabergoline 2/2014
    5/2014 Possible mild PCOS in addition to hyperprolactinemia??
    7/2014 Adding probable tubal factor to the diagnosis list
    9/2014 And now adding hypothyroid to the list- Started synthroid 9/2014
    Cycles 1-4 - Sept.-March- All Anovulatory 
    IUI #1 March/April-  Clomid 50mg + Clomid 100mg +Trigger + IUI #1 = BFN
     IUI #2 April/May-Clomid 100mg + Clomid 150mg + Trigger + IUI #2 + Endometrin=BFN
    IUI #3- June- Follistim 75iu + Trigger + IUI #3  Benched due to a 40 mm cyst. :-(
    IUI #3- July- Follistim 75iu + Trigger + IUI #3 + Endometrin = BFP! on 7/25/14
    Slowly rising betas - Ectopic suspected on 8/8/14 & confirmed on 8/11/14
    Methotrexate on 8/12/14 -HCG negative on 9/2/14
    IVF #1- November- Antagonist protocol: 11/1: start stims, 200iu of Follistim; 11/12 ER 17R/14M/14F; 11/17 5 day transfer of two blasts, 2 blasts and 2 expanding morulas frozen; 11/22 BFP!! (On FRER at 5dp5dt)
    Betas: 9dp5dt 205, 11dp5dt 497, 14dp5dt 1,709
    u/s at 5w0d- 1 sac; u/s at 6w0d 1 baby with heartbeat, another sac without a heartbeat
    image


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