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Anyone Start Ganirelix Late?

lilycakes78lilycakes78 member
in Infertility
Hi Ladies,

These past 24 hours I've been stressing! Today is day 8 of stims. Yesterday at my monitoring appointment the RE told me to start Ganirelex the following night (which will be tonight, day 8). I didn't think much of it until I got to work and started Googling! Big Mistake!!! It seems that most people start it on day 6 of stims. Also, it seems like a common cue to start it is a follicle that is 14 and E2 over 400. Well, I have one 14 follicle, the rest smaller, and my E2 is a little over 600. It even says on the RE's website that they start people on Ganirelex once they have one or two 13mm follies!!

I'm so afraid I will ovulate early! I was already surging before every IUI I did usually day 12. It happens so fast. I called the IVF nurse yesterday and was very upset and worried. She said she sat down with the doctor and went over everything again and he still felt I should not start Ganirelix last night! So, I'm just sitting here trying not to ovulate and counting down the minutes until I can inject it tonight. LOL! 

Has anyone else started Ganirelix as late as day 8 and been ok?

Thanks in advance!


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Re: Anyone Start Ganirelix Late?

  • tptbabetptbabe member

    I started on day 7 of stims (CD9), so pretty close? I always had a long LH surge and needed Ganirelix for IUI as well, but we were fine :) I had 4 follicles in the 13-14mm range when we started the Ganirelix for IVF, but I don't know what my E2 was at? We ended up having 18 eggs retrieved and 14 mature, so everything worked out perfectly on that end!

    I was pretty stressed out about it as well, and I think everybody worries that they're going to ovulate prematurely, but it's very rare. You just have to put your faith in the RE and not worry unless they give you a reason to!

    image imageimage
    image

    ***EVERYONE WELCOME***
    TTC #2 with assistance since 03/11
    Me: 33, Autoimmune (Hashimotos and FMS/CFS)
    Treated with Synthroid, acupuncture, TCM and supplements
    DH: 33, MFI (very low on all counts, high antibodies, hemochromatosis)
    Many treatments tried, none successful

    IVF/ICSI #1 05/14 - EPP/Antagonist, Gonal-F and Luveris, 18R, 14M, 13F - SET of 1BC, all arrested on day 5 - C/P
    Genetic testing = normal, DNA Frag = excellent
    IVF #2 03/15 - Long protocol with Suprefact, Gonal-F, and possibly Luveris, adding in PICSI
     
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  • saratryingsaratrying member
    I never started it until day 8 or 9. Once I started on day 10. You're fine. 
    TTC since 11/09
    me: 39 DH: 36      dx: unexplained (ugh) 

    January 2011 - December 2012: 4 cycles w/Clomid; 9 IUIs w/Follistim & Menopur;  two IVF cycles converted to IUI (poor response/dominant follicle) 

    August 2014 IVF (antagonist protocol: Menopur, Follistim, Ganirelix, dexamethasone): 13 eggs, 9 mature, 8 fertilized w/ICSI; 0 frozen, 3 transferred day 5 = BFN

    October 2014 IVF (micro-lupron protocol: mircrolupron, Menopur, Follistim, dexamethasone): 8 eggs, 4 mature, 3 fertilized w/ICSI; 3 transferred day 3 = BFP! Beta 1=121; Beta 2=287; Beta 3 =678. Miscarriage @ 8w2d. :(
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  • aliciafiggyaliciafiggy member
    I think you're fine. I started it late too, probably day 7 and my estradiol level was through the roof at like 1,000. I didn't ovulate early.
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  • Marissa6609Marissa6609 member
    I started late as well, day 9 of stims. I stressed about it too. In hindsite, I should have just trusted my doctor and left the stress for other things. I am sure you will be fine :)




    ** Losses Mentioned **
    Me(32) - Low AMH (0.46) and DH(33) - All good!
    May 2014 - IUI (Follistim) = BFP! Ectopic. Surgery June 2014.
    August/Sept 2014 - IVF #1. BFP! Chemical Pregnancy.
    November 2014 - IVF #2; ER only - PGS testing 3 Frosties.
    December 2014 - FET #1 - Beta on 12/17!  BFP  *It's TWINS*

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  • lilycakes78lilycakes78 member
    Thanks so much, ladies! Big hugs to all of you! You have really made my day. It's hard to trust the doctors, but sometimes you just have to. I'm glad to hear that I'm not alone in starting late.

    I'll try to calm down until my appt tomorrow. Thanks again!


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