Beta #2 and progesterone

Re: Beta #2 and progesterone

• missmarypoppins member

  September 2014

  I'm so sorry you're going through this. I would ask about adding in oral progesterone or PIO in addition to the cream and or suppositories. It's not like you're going to OD on progesterone so it can't hurt. It's really great that your beta is right on track though. And the blood is brown not red or pink, another great sign. Keep us posted! ((Hugs))

  Me: 30 DH: 30 ~ TTC #1 Since August 2011 

  BFP #1 2/28/13, Ectopic, Tubal surgery 3/25 

  Began RE testing 8/8, Dx Unexplained, 

  IUI #1 11/1=BFN Moving on to IVF 

  IVF #1 12/2 ER 8R 7M 4 fertilized

  12/7 Transferred 2 "perfect" little blasts 12/17 BFN

  New DX= DOR, I fu*kng hate IF

  1/14 Hysteroscopy, new clean uterus!

  IVF #2: bcp, Lupron, follistim 300, menopur 225. 2/21 8R 4M 3F. 3dt of 2 perfect embryos. 1 little penguin 

   3/10 BFFN

  Regrouping. Seeing reproductive immunologist Dr. Kwak Kim 6/10 

  Kwak Kim protocol: Metformin 1000mg, vitamin D 4000iu, vitamin E 400iu, baby aspirin, Metanx, levothyroxine 75mcgs 

   Surprise BFP 9/21!!! Beta #1 247, Beta #2 630. Miscarried 10/13

  
  

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• Neesey member

  September 2014

  And just remember that the supps don't show up in your blood work. I'm glad they are getting you in.

   

     

  TTC since 3/2011 Adenomyosis, LPD, hypothyroidism. 
  

  BFP on 7/20/12 after 4 cycles Clomid + IUI 

  2 large subchorionic hematomas & no heartbeat at 7w6d   

  D&E 8/18/12 Sonohysterography found septum and necrotic tissue.   

  Hysteroscopy to remove both 10/5

  IUI #5-7 50mg Clomid + trigger = BFN  

  IUI #8 Femara + Bravelle + HCG + Progesterone = BFP 3/27/13

  Beta 1 (13dpo) = 169  Beta 2 (17dpo) = 1073  No heartbeat at 9w3d. 

  D & C 5/10/13  Triploidy 69 (paternal inherited)

  IVF #1 with ICSI and PGS 11R 8M 5F 2 biopsied/frozen

  PGS results = 1 with trisomy 13 & 1 good embryo for FET 

  FET #1 EV, estrace, nitro patches.  Cancelled due to thin lining

  FET #1.2 oral estrace, f'ing nitro patches and no delestrogen.  Transfer 12/31. BFN

  PAIF/SAIF welcome

  Surprise BFP on 6/13/14  Our only unmedicated bfp ever.

  Beta #1 339  Beta #2 649 44 hour doubling time

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• gsancho member

  September 2014

  I'm sorry you're dealing with this.  I agree with everything @missmarypoppins said.  I'd ask about his thoughts on doing PIO, and I also think it's still a good sign that the spotting is brown.

  
  
  Me 33, DH 37 -- TTC since Jan'12 -- Low AMH (0.78) & endo, SA w/ low motility
  IUI's 1-3 = BFN, IVF converted to IUI 4/13 = BFN
  IVF 1.2: 8R 6M 4F -- 2 blastocysts frozen, FET 8/15 = BFP!!
  Beta #s = 445;1,098; 9,545  -- EDD 5/2 -- Team Pink!

  Camila Josephine arrived 4/30

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• hopeby2015 member

  September 2014

  What everyone else said but I'd just repeat this to emphasize - I think u should ask for pio in addition to the suppositories! Good luck! Hope all is well at your appointment!

  
  *May Siggy Challenge - Parenting Fails*
  
  
  
  

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• pblge member

  September 2014

  CarSaidYes said:

  Well guys I'm scared shitless. My beta came back at 1576 which is right on track. But my progesterone dropped from 11.4 to 9. I'll be 5 weeks tomorrow. This morning I had more spotting. It was a brownish color. I called my RE and in freaking out so they are taking me in today for an exam and since my rH is negative I'll most likely need a shot. Ok just scared because this is exactly how my last loss went. Also, they are changing my progesterone from suppositories to cream. Any thoughts or advice.

  These tests have error, so I wouldn't necessarily worry that your progesterone is decreasing--it's just still low (I would imagine the margin of error is great than the difference between those two numbers). As others said what you've been doing won't show up in the blood stream, so this doesn't reflect the progesterone support your LO is getting. That said, I'm extremely perplexed that they're switching you to the cream. Everything that I've read says that is a LESS effective mechanism of delivery, and I would encourage you to ask about PIO if you want to up your progesterone intake. Again, if you're doing something like Crinone or Endometrin, the probability is that your pregnancy is well-supported with progesterone, even if your blood tests aren't very high. I don't see why they would take you off those and onto the creams.
  
  I'm Rh negative, too, and the shot isn't a big deal. The OB will test if you're Rh sensitized (unlikely if you got the shot with your prior loss), and if you're not your pregnancy will be easily managed.
  
  Sorry you're going through this, but it's very likely that all is well!
  

  **********************siggy/ticker warning**********************
  
  ***Losses mentioned.*** TTC #1 since May 2012. Me: 37, OH: 41. Ectopic August 2012 => tubal damage.   Stage 1 endo removed June 2013. IVF #1 Oct/Nov 2013: Long Lupron with Gonal-F. 7R, 7M, 7F. 2 txfer@3d. Nothing frozen.  => M/C @ 8 wks. Selected RPL panel all normal. Very hyper and brittle response to stims. IVF #2 (antagonist protocol) Feb 2014 => Converted to IUI (Perfect conditions). BFN. IVF #2.1 w/ new RE June 2014: Antagonist protocol. 33R, 31M, 30F, 19 blasts to test!!! I made it through without crashing!! Hats off to Dr. Fancypants!! ET of one 5AB blast. BFN. 13 10 CCS'ed snowflakes! FET #1 PUPO as of 7/29 Betas: 8/7@24, 8/9@97, 8/11@334 (etc.) Two sacs on 8/15, one seen on 8/18 after a bleed. U/s 8/25 (6+3) "perfect": 5.9 mm + HB@120bpm! U/s 9/4 (7+6): 15.9 mm + HB@172 bpm! Please, PLEASE stick this time!!!!
  

  

  
  

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• 1220winterbride member

  September 2014

  the nurse at my clinic thinks my cervix bled a little from the suppositories. when you are pregnant its very easy to irritate your cervix. 

  
  

  Hoping you get great updates soon.

  
  My heart is as open as the sky.
  Read about it on the blog
  
  
  
  
  
  2 Corinthians 12:9 But he said to me, "My grace is sufficient for you, for my power is made perfect in weakness." Therefore I will boast all the more gladly about my weaknesses, so that Christ's power may rest on me.
  
  
  
  

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• intheplanningstage member

  September 2014

  I'm sorry that your progesterone dropped (fyi my dr's lab looks for 8 as a minimum, and with supplements you should be ok) but hopefully the brown spotting isn't even related. I had intermittent brown spotting from 5-9 weeks and it was terrible...but meaningless. Hope it's the same for you

  Our Novel of TTC:

  
  

  *Male Factor (low count and low motility), High Prolactin, and Polycystic Ovaries (March 2013)

  *Recurrent Miscarriage testing also revealed high anti-phospholipids & single MTHFR mutation. (Feb 2014) 

  
  *IVF (07/2013): BFP-Natural Miscarriage @ 5 weeks* Madison Riley
  *FET #1 (10/2013): BFN
  *FET #2 (12/2013)- BFP-Missed Miscarriage at 8 weeks Kyle Andrew
  *Chromosomes and Karotyping tests were both normal.We lost a healthy baby boy
  *FET #3 (04/2014) was cancelled after finding Chronic Endometritis

  *Miraculous BFP July 2014!! (I was taking baby aspirin and Cabergoline to stay regulated while "taking a break from TTC" and waiting to consult with a reproductive immunologist!!!) 

  
  

  Our healthy baby girl was born 03/10/15 thanks to daily Lovenox injections and baby aspirin. There are no words for how grateful I am for our rainbow baby.

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• CarSaidYes member

  September 2014

  Thanks ladies for all the advice. Just picked up my new meds. He switched me to Crinone (8%)

  Me: 26 (IC/PCOS-2000mg of Metformin daily)

  June 2014- HSG=clear

  DH: 27 (SA results were great minus the slightly low morphology)

  Started dating DH in 2002 at 14 years old

  Married on 03.01.2014

  Officially TTC since April 2014 

  January 2013- Surprise BFP, m/c at 6 weeks, D&C 2 Weeks later

  April 2014- First RE appointment

  July 2014- IUI#1-Canx due to scar tissue and polyps. TI with the help of Ovidrel. BFN

  August 2014- Hysteroscopy to remove scar tissue and polyp

  September 2014- IUI #1.1-100mg Clomid, Ovideral, 11.5 million swimmers=BFP

  EDD-6/3/15- Our sweet baby Ryan was born on 1/6/15 and is in the arms of an Angel

  Dx with IC on 1/6/15

  
  

  
  

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• pblge member

  September 2014

  CarSaidYes said:

  Thanks ladies for all the advice. Just picked up my new meds. He switched me to Crinone (8%)

  Great! Crinone isn't what I thought you meant.
  

  **********************siggy/ticker warning**********************
  
  ***Losses mentioned.*** TTC #1 since May 2012. Me: 37, OH: 41. Ectopic August 2012 => tubal damage.   Stage 1 endo removed June 2013. IVF #1 Oct/Nov 2013: Long Lupron with Gonal-F. 7R, 7M, 7F. 2 txfer@3d. Nothing frozen.  => M/C @ 8 wks. Selected RPL panel all normal. Very hyper and brittle response to stims. IVF #2 (antagonist protocol) Feb 2014 => Converted to IUI (Perfect conditions). BFN. IVF #2.1 w/ new RE June 2014: Antagonist protocol. 33R, 31M, 30F, 19 blasts to test!!! I made it through without crashing!! Hats off to Dr. Fancypants!! ET of one 5AB blast. BFN. 13 10 CCS'ed snowflakes! FET #1 PUPO as of 7/29 Betas: 8/7@24, 8/9@97, 8/11@334 (etc.) Two sacs on 8/15, one seen on 8/18 after a bleed. U/s 8/25 (6+3) "perfect": 5.9 mm + HB@120bpm! U/s 9/4 (7+6): 15.9 mm + HB@172 bpm! Please, PLEASE stick this time!!!!
  

  

  
  

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• CarSaidYes member

  September 2014 edited September 2014

  Here's an update. So the RE looked at my cervix and said it looked great and no sight of blood. Then she did an u/s and we saw a sac (which makes me happy) and she said it's exactly what she expected to see at my stage in the game. She looked at my ovaries and saw where I ovulated from (assuming that's what makes the progesterone?) then she told me that there was no bleeding or sight of blood in the uterus. She advised me to start the gel tonight and drop the suppositories something about data and research... Lost her at that point for a min. Thank god my mom was there with mom me to hear her. She also wants me to stay home from work tomorrow and take it easy and see if the spotting returns. Her exact words were "from what I see everything looks normal". That's comforting. She's going to retest the progesterone and I have my 1st ultrasound in a week. I hope I can make it until then. Thank you guys for all the advice and comforting post. ETA: 2nd beta test came in today. Beta was at 1576 which is great and my progesterone dropped from 11.4 to 9.... Super depressed and scared about that. Hoping this crinone helps.

  Me: 26 (IC/PCOS-2000mg of Metformin daily)

  June 2014- HSG=clear

  DH: 27 (SA results were great minus the slightly low morphology)

  Started dating DH in 2002 at 14 years old

  Married on 03.01.2014

  Officially TTC since April 2014 

  January 2013- Surprise BFP, m/c at 6 weeks, D&C 2 Weeks later

  April 2014- First RE appointment

  July 2014- IUI#1-Canx due to scar tissue and polyps. TI with the help of Ovidrel. BFN

  August 2014- Hysteroscopy to remove scar tissue and polyp

  September 2014- IUI #1.1-100mg Clomid, Ovideral, 11.5 million swimmers=BFP

  EDD-6/3/15- Our sweet baby Ryan was born on 1/6/15 and is in the arms of an Angel

  Dx with IC on 1/6/15

  
  

  
  

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• turquoisequeen member

  October 2014

  I was on crinone with my IVF cycle (just stopped it a few days ago) and my IVF nurse told me that it absorbs better when you move around (contrary to what I thought... I was thinking lay down for awhile to prevent leaking) so after you put it in walk around for 5-10 minutes. And it WILL leak. I found mine leaked all the time but that does not mean it is not being absorbed. 

  
  

  Good luck!

  **Signature Warning**

  
  

  TTC since July 2013

  DX: Unexplained or possibly DOR and DH 2% morph

  3 IUIs May-July: all BFN

  IVF Sept 2014: 12R 10M 8F, 5 day eSET 9/15, 4 frosties

  Beta #1 353, Beta #2 651, EDD June 3

  
  

  TRUST in the LORD with all your heart and lean not on your own understanding. Proverbs 3:5

  
  

   

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• CarSaidYes member

  October 2014

  Well today after my ultrasound I asked my RE to recheck my progesterone level because it had dropped to 9 and it came back at 19.2. I am so happy. They are keeping me on the crinone just incase. Just wanted to update you ladies since you had given me some input.

  Me: 26 (IC/PCOS-2000mg of Metformin daily)

  June 2014- HSG=clear

  DH: 27 (SA results were great minus the slightly low morphology)

  Started dating DH in 2002 at 14 years old

  Married on 03.01.2014

  Officially TTC since April 2014 

  January 2013- Surprise BFP, m/c at 6 weeks, D&C 2 Weeks later

  April 2014- First RE appointment

  July 2014- IUI#1-Canx due to scar tissue and polyps. TI with the help of Ovidrel. BFN

  August 2014- Hysteroscopy to remove scar tissue and polyp

  September 2014- IUI #1.1-100mg Clomid, Ovideral, 11.5 million swimmers=BFP

  EDD-6/3/15- Our sweet baby Ryan was born on 1/6/15 and is in the arms of an Angel

  Dx with IC on 1/6/15

  
  

  
  

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