Miscarriage/Pregnancy Loss

We have an answer

My RE just called me at home (didn't want to give me potentially emotion inducing news at work -- so sweet & thoughtful) with the pathology results from my MMC/ D&C nearly two weeks ago. We actually have an answer. Trisomy 21. She said many Trisomy 21 embryos just have malformations that are simply incompatible with life -- more severe versions of the cardiac problems that Downs babies often have, for example. She also told me it was a girl. That part is sort of hitting me pretty hard.

On the plus side, it had nothing to do with my ability to carry a pregnancy. But it was due to my dusty old eggs, so that kinda sucks. Positive: it was a spontaneous error, not anything inherent in our DNA. Negative: all my frosties are from 35 year old eggs and the same error could have spontaneously occurred in any one of them.

RE thinking it is not worth the risk of thawing, testing, refreezing & rethawing the frosties, though, as we would likely lose some in the process. It would not do much good to know we had a healthy embryo if we killed it to test it.

So much to think about and process. But I guess it is good to have an answer. I had pretty much prepared myself for not getting an answer...

*************Siggy Warning. Loss mentioned.************




Me: 36, DH:37

Married 4/2010, TTC since 7/2011

Dx: Officially Unexplained (I have Polycystic Ovaries diagnosed via ultrasound, but few classic PCOS symptoms, he has mild MF issues. So... not issue free, but nothing so severe as to explain IF)

I also deal with post-surgical Hypothyroidism following Thyroid Cancer in 2009, but under control with Levothyroxine

4 months Clomid (thinned lining) and 10 months Letrozole (every indication that I responded perfectly)

6 failed IUIs in 2013, 3 with trigger

IVF #1 in March 2014

ER 3/21/14, 31R/21F, 12 frosties!

ET 3/26/14, 1 perfect blast transferred: BFN

FET#1 5/28/14, 2 "beautiful" early blasts transferred. BFP!!

Beta #1 (6/11/14) 798; Beta #2 (6/18/14) 7,966.

1st u/s (6/25/14) showed 2 sacs, 1 empty & 1 with a beautiful little bean doing what it needs to do!

EDD 2/14/15, missed miscarriage, DX: Trisomy 21. D&C 8/1/14

FET#2 Transferred 3 embies, 2 looking pretty good, one not so much. BFN.

IVF#2 January 2015, tentative ER 1/23

Re: We have an answer

  • ((hugs))I hope these answers give you some peace.  GL with going forward.
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  • Thanks, ladies. I've been thinking about this a lot this last week and have done a lot of research. Having an explanation really has gone a long way to giving me some peace about what happened. It wasn't anything that I did wrong and there really wasn't anything we could have done to have had a different outcome. That knowledge is powerful. I am still devastated and would have loved to have my little girl, Downs and all, but it just wasn't in the cards. Knowing the cause also makes me more comfortable moving forward. There is always a chance it could happen again... But there is no reason to expect that it will. My follow-up with RE is in a week. We'll know more after that about when we might be able to try again.

    *************Siggy Warning. Loss mentioned.************




    Me: 36, DH:37

    Married 4/2010, TTC since 7/2011

    Dx: Officially Unexplained (I have Polycystic Ovaries diagnosed via ultrasound, but few classic PCOS symptoms, he has mild MF issues. So... not issue free, but nothing so severe as to explain IF)

    I also deal with post-surgical Hypothyroidism following Thyroid Cancer in 2009, but under control with Levothyroxine

    4 months Clomid (thinned lining) and 10 months Letrozole (every indication that I responded perfectly)

    6 failed IUIs in 2013, 3 with trigger

    IVF #1 in March 2014

    ER 3/21/14, 31R/21F, 12 frosties!

    ET 3/26/14, 1 perfect blast transferred: BFN

    FET#1 5/28/14, 2 "beautiful" early blasts transferred. BFP!!

    Beta #1 (6/11/14) 798; Beta #2 (6/18/14) 7,966.

    1st u/s (6/25/14) showed 2 sacs, 1 empty & 1 with a beautiful little bean doing what it needs to do!

    EDD 2/14/15, missed miscarriage, DX: Trisomy 21. D&C 8/1/14

    FET#2 Transferred 3 embies, 2 looking pretty good, one not so much. BFN.

    IVF#2 January 2015, tentative ER 1/23

  • I'm so glad that you got some answers.  I'm so sorry for your loss.  ((hugs))
  • With your strength, you will overcome! My sister had 3 babies all after the age of 37! Her youngest was at 43. Don't loose faith, you still have some spunky eggs in there!
  • NewMrs07NewMrs07 member
    edited August 2014
    Spring- so very sorry for your loss. I just mc'd at 8 weeks and I didn't have anything tested but I'm glad I didn't find out the sex. Since I have a boy already I would be devastated if I found out my mc was a girl :'(
    Me: 44 DH: 42. DS born healthy at 40 weeks 8/24/09. TTC since then with no luck or ART. Surprise BFP 8/6/14... MMC @ 8 weeks 4 days... Miss you everyday sweet baby angel.
  • With your strength, you will overcome! My sister had 3 babies all after the age of 37! Her youngest was at 43. Don't loose faith, you still have some spunky eggs in there!

    *** siggy warning *** Purduepat- seriously? Keep those insensitive comments to yourself. Your sister's fertility has nothing to do with other women's fertility. Comments like that are super annoying.
    Me: 44 DH: 42. DS born healthy at 40 weeks 8/24/09. TTC since then with no luck or ART. Surprise BFP 8/6/14... MMC @ 8 weeks 4 days... Miss you everyday sweet baby angel.
  • New Mrs. I was trying to help, what you think is insensitive might not be to others. I am concerned for her so if she felt it was a insensitive than I am truly sorry. I just had a D&C on Monday, so I am going through this too and I am 37. I was giving hope, which is what I am holding on to.

    I would never tell someone else to hold their comments to "yourself" but clearly you feel above your own advice. I hope that my own experience and personal thoughts don't continue to "annoy you." Wow.
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