Trouble TTC

We have a plan - input appreciated.

I just had my RE consult yesterday.  It went quite smoothly because my ob/gyn ran so many test before the referral and actually called the RE to discuss my case so the RE had a good picture of what was going on.  I was impressed by that!  Anyway, there are still some tests to run (saline sonohystogram, HSG, etc.) and update some other tests.  My husband still has to do his SA and blood work.  So I am currently taking progesterone to trigger my cycle and over the next couple weeks we’ll get the remaining tests done.  Once completed and updated, we’ll review with the RE and begin treatment assuming there are no huge surprises.<?xml:namespace prefix = "o" ns = "urn:schemas-microsoft-com:office:office" />

 

Preliminary plan:  She will start me on Metformin and Clomid.  If my husband’s SA and labs come back normal, we’ll try to conceive on our own at home.  If there are any issues with the SA and labs, we’ll consider IUI.  I have tons of eggs so lots of monitoring will happen to avoid multiples.  If I don’t respond to metformin and Clomid, she’ll add another medication (I forgot to write down what that one was…oops).  If that isn’t successful, we’ll consider IVF with a one or two egg transfer.  Since I have so many eggs, she does not recommend injectables due to the chance of multiples. 

 

In the meantime, she told me to cut back my caffeine intake to no more than 2 cups per day (I’m a full time employee, full time wife and almost full time grad student…so I live on coffee).  Also, begin taking a prenatal vitamin and start taking Pregnitude after all labs are completed.  Of course, if labs and SA come back with any major surprises, we’ll reevaluate.

 

The RE told me, “We’ll get you pregnant.  It is just a matter of how to get you pregnant with just one.”  She was very confident in my case so I feel better about this whole thing, but still anxious to get it all going. 

 

From everything I’ve read here and on medical sites, this seems to be a pretty typical treatment plan for “thin” PCOS.  Any thoughts from you lovely (and knowledgeable) ladies?

Me: 28  MH:35

Married September 2012. TTC since September 2013

June 2014 - Dx w/ significant PCOS and referred to RE.

July/August 2014 - Testing complete: Testosterone & AMH very high, FSH slightly high, Vitamin D low, tubes and lining all lovely. DH SA: A+

Cycle 1 (Nov 2014): 2.5 mg Letrozole/Ovidrel/TI = BFN

Cycle 2 (Dec 2014): 5 mg Letrozole/Ovidrel/TI - BFN

Cycle 3 (Jan 2015): 5mg Letrozole/Ovidrel/TI - BFN

WTF consult scheduled for 1/29

Re: We have a plan - input appreciated.

  • It seems like you are in good hands. Good luck!
    Me: 34 | He: 40
    TTC since 08/2012
    DX: DOR




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  • Good luck!

    DH: 34  
    Aug 2013 - SA: Counts & Motility = great, Morph = 1%; RE didn't seem too concerned

    Me: 26
    Jan. 2014 - Blood work ordered by obgyn:  Prolactin = high & AMH = low (0.73)
    Feb. 6, 2014 - Repeat blood work ordered by obgyn:  Prolactin = normal & AMH = low (0.9)
    Feb.  20, 2014 - First appointment with RE
    Feb. 24, 2014 - HSG scheduled;  DX:  one tube definitely open & one tube could be blocked
    Mar. 7, 2014 - CD 21 Blood work for Progesterone; DX:  Progesterone level at 5.2; shows I ovulated but was low
    Mar. 28, 2014 - Laparoscopy; DX:  Tubes open.  Found some endometriosis and had that removed.
     
    History:
    Started TTC:  June 2012
    June 2012 - March 2013:  When it Happens/it happens method = BFN
    March 2013:  Started using Fertility Friend
    Cycles 1 - 15 with Fertility Friend = BFN
    Cycle 16 - Benched due to Laparoscopy
    Cycle 17 - Natural Cycle = BFN
    Cycle 18 - Natural Cycle = BFN
    Cycle 19 - Natural Cycle = BFN
     

    Current Cycle:
    Cycle 20 = Natural Cycle


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  • Sounds like your consultation went well.  Good luck as you move forward!
  • edited June 2014
    Lean PCOS'er here. I'm not on Metformin but am on Clomid + Trigger. I think your plan sounds good!

    Missed M/C natural cycle 10/2013

    DX PCOS 3/2014

    2 cycles Clomid 50 mg + Ovidrel + TI

    1 cycle Clomid 50 mg + TI - no response stair-stepped to Clomid 75 mg + Ovidrel + TI

    1 cycle Clomid 50 mg + Ovidrel + IUI

    1 cycle Letrozole 7.5 mg + 150 mg Follistim + Ovidrel + TI

    1 cycle Letrozole 7.5 mg + 150 mg Folistim + Ovidrel + IUI

    1 cycle Letrozole 7.5 mg + 150 mg Follistim  - no response, repeated Letrozole 7.5 mg + 150 mg Follistim + Ovidrel + IUI = success! 12/2014

    Beta 1 - 15 dpiui, 324, Beta 2 - 17 dpiui 750. Twins!!

    My Blog: pcosandpizza.blogspot.com


  • junerosesjuneroses member
    edited June 2014
    Sounds like a good plan - my RE diagnosed me with pcos, too, and we are following the same course except with letrozole good luck on the remaining tests!
    Me (33), PCOS. Bloodwork normal, AMH slightly high, HSG clear 
    DH (40) SA good 
    Trying since 1/2012, RE 6/2014 
    Letrozole & TI June 2014-September 2014 -BFN
    October 2014 - IUI #1, lertozole - BFN
    November 2014 - IUI cancelled due to holiday, TI & Lertozole - BFN
    December 2014 - TI 
    January 2015 - IUI #2 - ?

  • Looks like you have a good plan and some good doctors too! Best of luck!

    Trying to have baby #1 since April 2013

    DH SA March,May 2014 - Low motility and shape issues. On vitamins per RE to help

    Me testing April 3, 2014 - FSH and LH good, HSG showed blocked right tube

    April 29, 2014 - First RE appt., right tube needs to be removed and possibly left also if

    it's bad too. RE suggests going straight to IVF

    June 4, 2014 - LAP/HSC and unexpected endo. removed but tubes got to stay!

    June 13, 2014 - Post-Op appointment. We decide where to go next since main issue

    is MFI influenced. Trying naturally until decision... Repeat SA  in September. Aiming for IUI #1 November 2014.

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  • That sounds like a very thorough plan. Our RE just goes one step at a time, and never talked about anything further than the first treatment (Letrozole and IUI), but I think he's wary of scaring us since we waited so long for treatment in the first place, lol! Actually it would be nice to hear his take on our long-term plan. Good luck on your testing!
    January 3T Siggy Challenge - New Year's Resolutions
    image
    imageimage

    Me (29), DH (30) TTC actively 54 55+ cycles | All BFNs
    MFI (low everything) | Endo Stage 1 & Stenotic Cervix (treated) | PCO
    Married - July 2008 | Started TTC - Jan 2009RE Visit #1 - Mar 2014 
    IUI #1 ICI #1 - June | IUI #1.1 Laparoscopy - Aug
    IUIs #1.2, 2, 3 - Sept, Oct, Nov (Letrozole) - BFNs 
    IUI #4 - Dec (Bravelle) | IUI #5 - Dec/Jan (Bravelle) - 5 follies + TI - BFNs
    IUI #5.1 - Jan (Bravelle) Cancelled 
    Planning to start IVF in March!
    ***All Welcome***
  • Thank you everyone!  Your well wishes mean a lot to me!!!!

    Me: 28  MH:35

    Married September 2012. TTC since September 2013

    June 2014 - Dx w/ significant PCOS and referred to RE.

    July/August 2014 - Testing complete: Testosterone & AMH very high, FSH slightly high, Vitamin D low, tubes and lining all lovely. DH SA: A+

    Cycle 1 (Nov 2014): 2.5 mg Letrozole/Ovidrel/TI = BFN

    Cycle 2 (Dec 2014): 5 mg Letrozole/Ovidrel/TI - BFN

    Cycle 3 (Jan 2015): 5mg Letrozole/Ovidrel/TI - BFN

    WTF consult scheduled for 1/29

  • Good luck with your remaking tests, it sounds like you have a great plan!



    ********Siggy/Ticker Warning***********



    Me (35) no known issues DH (37) MFI. TTC 21 months (24 cycles)
    Dx MFI with low to normal count, low motility, morphology 3%
    HSG normal, ultrasound and labs on me all normal. 

    1 cycle of Clomid 50mg and TI, unmonitored by OBGYN= BFN
    1 cycle of Clomid 50mg and IUI, unmonitored by OBGYN= BFN
    Started seeing an RE!!
    2 more cycles of clomid 50mg (great response), with IUI and Pregnyl trigger (4.8-8 mil good ones after wash) = all BFN
    1 cycle of clomid 50mg (3-7) followed by Follistim 75iu (7-11) + IUI = BFN
    December 2013 DH saw urologist and is taking Anastrozole, CoQ10, and L-Carnitine
    IUI #5 natural cycle (needed a med break) = BFN
    IUI #6 Follistim 75iu (CD3-10) + Pregnyl (CD11) + IUI (final count after wash 300K) = BFN
    IUI #7 Follistim 75iu (CD3-9) + Pregnyl (CD11) + IUI on 2/20 (post wash count 12.5 million)= BFN
    IUI cancelled (DH OOT) Clomid 50mg (CD3-7) 1 follicle +(not well timed) TI = BFN
    IUI #8 and last one!! Clomid 100mg (CD3-7) +OPK before US + IUI 4/17 (post wash 8.5 mil)= BFN

    Pre-IVF testing complete! SHG great and measurements taken! Labs for infectious diseases completed, FSH (5.4), TSH (1.6), Prolactin (11), AMH (2.6), Estradiol (40).

    Started BCP 5/29 and Lupron 6/11 prep for IVF #1! Started follistim 225u/day on 6/28. Monitoring on 7/2 >15 follicles measuring 11-14, E2 758. Monitoring on 7/5 all ready to go!! Great follicle sizes and lining is at 9. Tigger 7/5, ER 7/7 16R 9M 3F. Stimmed too fast in just 7 days. 7/10 3dt of 2 8-cell grade 2 & 4. 7/14 P4 >60.
    Holy crap BFP!!!
    Beta #1 (14dpo) 7/21 112 Beta #2 (16dpo) 7/23 286 a Beta #3 (18dpo) 7/25 761 Beta #4 (21dpo) 2631!!! Hold on tight little embies!!
      First Ultrasound 8/7- 1 perfect little bean with a beating heart 117bpm!! EDD 3/30.
    Second ultrasound 9/2 Little bean measuring a few days ahead with a heart rate of 161!



    PAIF/SAIF/All Welcome!

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    March 15 Siggy Challenge: You had one job

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