Community› The Bump Message Boards› Trouble TTC
Trouble TTC
New Discussion

Advice (high estrogen) - whether to cancel this cycle

emmuffyemmuffy member
in Trouble TTC

Hi all... not sure what to do about my current cycle. This is m 5th IUI cycle (unmedicated). We are using donor sperm and have 4 units left. We were planning to try 1-2 more times with IUI, and then move to IVF.

My estrogen was abnormally high on day 3 (more than triple any of my previous readings, and more than double the limit of what is considered the normal range for day 3). High estrogen at day 3 can be associated with poor egg quality. However, we retested today (Day 5) and the estrogen was back within normal limits. My doctor is willing proceed with the cycle given today's results, but I'm wondering if I should just sit this cycle out. I don't want to bother inseminating if my follicle(s) aren't likely to be good quality. My dominant follicle this cycle also appears to be developing on my right side, where I have a 1.5 cm cyst, and I have no idea if that's going to interfere with things.

Does anyone have any experience with high estrogen? Did you proceed with the cycle or skip it?

Official diagnosis: Unexplained IF. I am 32. I have low ovarian reserve (low AMH), and poor egg quality. I've also been diagnosed with mild glandular developmental arrest (lining problems, detected with EFT).

We are using open ID donor sperm. IUIs #1-7=BFN. IVF September 2014 antagonist protocol, 8R,5M,3F, 5 day transfer of 1 morula = BFN. IVF#2 planned for January 2015 (antagonist protocol + HGH).

Image and video hosting by TinyPic image

Report Reply to Post

Re: Advice (high estrogen) - whether to cancel this cycle

  • emmuffyemmuffy member
    We were trying to keep things as 'natural' as possible - just a personal preference, and wanting to avoid the risk of multiples. We were thinking of introducing Clomid on cycle 6 if #5 didn't work. My doctor is (gently) encouraging Clomid.

    Official diagnosis: Unexplained IF. I am 32. I have low ovarian reserve (low AMH), and poor egg quality. I've also been diagnosed with mild glandular developmental arrest (lining problems, detected with EFT).

    We are using open ID donor sperm. IUIs #1-7=BFN. IVF September 2014 antagonist protocol, 8R,5M,3F, 5 day transfer of 1 morula = BFN. IVF#2 planned for January 2015 (antagonist protocol + HGH).

    Image and video hosting by TinyPic image

    Report Reply
  • Loading the player...
  • BunnyBerryBunnyBerry member
    I'm sorry that I don't have any advice about your estrogen numbers! Have you asked the doc if that odd temporary jump signifies a problem with egg quality this cycle?

    Clomid or other meds could take care of some different issues that might be undiagnosed but holding you back. I also want to suggest that having a cycle or more or Clomid or even injects can give the RE key feedback on your body's reaction to fertility meds, which can help them plan a more effective IVF first cycle if needed. But, that doesn't take into account your desire to reduce the risk of multiples, so I would just like to say good luck with whatever you choose!
    January 3T Siggy Challenge - New Year's Resolutions
    image
    imageimage

    Me (29), DH (30) TTC actively 54 55+ cycles | All BFNs
    MFI (low everything) | Endo Stage 1 & Stenotic Cervix (treated) | PCO
    Married - July 2008 | Started TTC - Jan 2009 | RE Visit #1 - Mar 2014 
    IUI #1 ICI #1 - June | IUI #1.1 Laparoscopy - Aug
    IUIs #1.2, 2, 3 - Sept, Oct, Nov (Letrozole) - BFNs 
    IUI #4 - Dec (Bravelle) | IUI #5 - Dec/Jan (Bravelle) - 5 follies + TI - BFNs
    IUI #5.1 - Jan (Bravelle) Cancelled 
    Planning to start IVF in March!
    ***All Welcome***
    Report Reply
  • emmuffyemmuffy member
    Thanks! That's a really good point about the IVF. Frankly, I'm finding it really hard getting the BFNs every month and I'm seriously considering starting Clomid next cycle just to increase my chances and hopefully get a better result. I sent a rather long email to my clinic and the doctor wrote me a very thorough response about what to do with this cycle. Basically, she is not concerned about egg quality this cycle because the estrogen came right back down after spiking so high. So... I'm going to go for it, wish me luck! :)

    Official diagnosis: Unexplained IF. I am 32. I have low ovarian reserve (low AMH), and poor egg quality. I've also been diagnosed with mild glandular developmental arrest (lining problems, detected with EFT).

    We are using open ID donor sperm. IUIs #1-7=BFN. IVF September 2014 antagonist protocol, 8R,5M,3F, 5 day transfer of 1 morula = BFN. IVF#2 planned for January 2015 (antagonist protocol + HGH).

    Image and video hosting by TinyPic image

    Report Reply
  • Lillovebug79Lillovebug79 member
    Good luck!! I would definitely look into trying clomid next cycle, it will hopefully give you better odds of success. Plus like PPs said, it will give your doctor some good info about your response.



    ********Siggy/Ticker Warning***********



    Me (35) no known issues DH (37) MFI. TTC 21 months (24 cycles)
    Dx MFI with low to normal count, low motility, morphology 3%
    HSG normal, ultrasound and labs on me all normal. 

    1 cycle of Clomid 50mg and TI, unmonitored by OBGYN= BFN
    1 cycle of Clomid 50mg and IUI, unmonitored by OBGYN= BFN
    Started seeing an RE!!
    2 more cycles of clomid 50mg (great response), with IUI and Pregnyl trigger (4.8-8 mil good ones after wash) = all BFN
    1 cycle of clomid 50mg (3-7) followed by Follistim 75iu (7-11) + IUI = BFN
    December 2013 DH saw urologist and is taking Anastrozole, CoQ10, and L-Carnitine
    IUI #5 natural cycle (needed a med break) = BFN
    IUI #6 Follistim 75iu (CD3-10) + Pregnyl (CD11) + IUI (final count after wash 300K) = BFN
    IUI #7 Follistim 75iu (CD3-9) + Pregnyl (CD11) + IUI on 2/20 (post wash count 12.5 million)= BFN
    IUI cancelled (DH OOT) Clomid 50mg (CD3-7) 1 follicle +(not well timed) TI = BFN
    IUI #8 and last one!! Clomid 100mg (CD3-7) +OPK before US + IUI 4/17 (post wash 8.5 mil)= BFN

    Pre-IVF testing complete! SHG great and measurements taken! Labs for infectious diseases completed, FSH (5.4), TSH (1.6), Prolactin (11), AMH (2.6), Estradiol (40).

    Started BCP 5/29 and Lupron 6/11 prep for IVF #1! Started follistim 225u/day on 6/28. Monitoring on 7/2 >15 follicles measuring 11-14, E2 758. Monitoring on 7/5 all ready to go!! Great follicle sizes and lining is at 9. Tigger 7/5, ER 7/7 16R 9M 3F. Stimmed too fast in just 7 days. 7/10 3dt of 2 8-cell grade 2 & 4. 7/14 P4 >60.
    Holy crap BFP!!!
    Beta #1 (14dpo) 7/21 112 Beta #2 (16dpo) 7/23 286 a Beta #3 (18dpo) 7/25 761 Beta #4 (21dpo) 2631!!! Hold on tight little embies!!      First Ultrasound 8/7- 1 perfect little bean with a beating heart 117bpm!! EDD 3/30.
    Second ultrasound 9/2 Little bean measuring a few days ahead with a heart rate of 161!


    PAIF/SAIF/All Welcome!

    image




    Pregnancy Ticker} 




    March 15 Siggy Challenge: You had one job

    image
    Report Reply
This discussion has been closed.
Choose Another Board
Search Boards
"
"