Anyone else have to do some priming with Estrace? I am unclear why I have to do that. Anyone know the answer? what type of side effects could I expect from that one?
===siggy warning====
Me: 40, DH: 42
Diagnosis: PCOS
TTC: May 2013
TX: IUI #1 with Follistim. Canceled due to too many follicles (10 + that were large); BENCHED
I can't offer any feedback on the why it's being used for priming, but I was on it post-IUI and didn't really have any side effects besides the telltale blue discharge.
I used it before my FET and am still using it. Its estrogen support and I believe it helps thicken your lining. It makes me super hungry, I'm bloated and my boobs are huge, sore and veiny!
******Siggy Warning**************
Me 29 - no known issues ( Highest FSH 10.1??)
DH- 36 - quite the perfect man!
TTC since 1/2011
IUI #1 March 2012
BETA #1 BFP
B/O at 6 weeks D&C @ 10 weeks
IUI #2-7 (2012)= BFN
IVF Jan 14 - Follistim, Ganirelix
22R, 8M, 8F
ET (1-14-14) - 1 Grade A 8 cell = BFN
FET (2-18-14) 1 grade A 12 cell and one early morula!
BETA#1 (3-3-14) =1,389 p4 17.4
BETA #2 (3-5-14) = 4,553 u/s showed one small g sac
U/S #2 (3-17-14) Shows two little beans with heartbeats!!! TWINS!!
Heartbeats were 119 & 120 beans measured (6 weeks 1 day) (6 weeks 2 days) found out at 20 weeks that baby B went to heaven 11/12/14 Baby girl arrived FET (1-24-16) Grade A early morula BETA #1 300 p4. 11.1 BETA#2 1300 u/s d 1 tiny babe 10/7/16 another sweet baby girl 4/18 SURPRISE + HPT Beta #1 6 weeks 16,202 p4. 13.2
Nov 2013 IVF/ICSI #1 - Protocol: BCP prep, high doses Menopur and Bravelle (12 days), ganirelex Results: 5 retrieved / mature, 4 fertilized, 1 arrested and 3 complex abnormal after day 3 PGS = Cancelled after ER Jan/Feb 2014 IVF/ICSI #2 - Protocol: Estrogen priming, high doses Menopur and Bravelle (11 days), microdose lupron Results: Cancelled after 11 days of stims due to low response and E2 levels Feb 2014 IVF/ICSI #3 - Protocol: No prep, low dose Menopur (6 days), ganirelex, Bravelle booster with trigger Results: 1 retrieved / 0 mature = Cancelled after ER
Officially moving on to embryo adoption! We used and love Embryo Adoption Services of Cedar Park October 2014 FET #1 - BCP/Lupron/Estrace/Prometrium, transferred 2 of 4 from match #1, BFN December 2014 FET #2 - BCP/Lupron/Estrace/Prometrium, transferred 2 of 4 from match #1, BFN March 2015 FET #3 - BCP/Lupron/Estrace/Prometrium, transferred 2 of 6 from match #2, BFN May 2015 FET #4 - BCP/Lupron/Estrace/Prometrium, lost 2 to thaw, transferred 2 of 6 from match #2, BFN October 2015 FET #5 - Natural cycle, lost 1 from match #3 and 1 from clinic backup to thaw, transferred 1 backup, BFN February 2016 FET #6 - Natural cycle, transferred 1 from match #4, B FREAKING P! Beta 1 = 162, Beta 2 = 316, doubling just over 48 hours
I am in an estrogen priming cycle now, didn't use estrace but used two other estrogen supplements, Estridol Varilate shots and Estrogen suppositories. My doctor said it makes the ovaries "listen" to the stimming meds and respond better.
Me 39, DH 40 Male Factor (severe oligospermia)
IVF#1-December 2013: Conversion Protocol @ SIRM, Canceled on day 10 of stims due to poor response
IVF#2- February 2014: Estrogen Priming Conversion Protocol @ SIRM (ER 2/22: (9R, 7M, 4F, All arrested, nothing to trasnfer)
I'm doing estrogen priming as well- my Re said it helps prepare the ovaries so they respond to the stimulation drugs better. In past cycles I have had a low response despite normal levels, so the estrogen will hopefully remedy that. GL as you continue!
TTC since 2008 Dh:34, no issues. Me:31, Endo, slightly hypothyroid, deformed ovary, paracentric inversion. 4 Gonal-F, Cetrotide, HcG, Crinone +TI cycles= all BFN Lap in 2012 to remove large unresolving cyst discovered endo and double lobed ovary. 6 Gonal-F, Cetrotide, HcG, Crinone IUI cycles= All BFN, 1st IVF w/ICSI- June '13 Antagonist: Gonal-F, Menopur, Ganirelix, HcG, Estradiol, Crinone= 7 retrieved, 4 mature, 1 unfertilized, 2 abnormally fertilized, 1 normally fertilized. 2DT of only embryo and our miracle BFP. Our beloved baby boy was born sleeping Oct. 13, 2013 due to pROM/IC/Uterine infection. 2nd IVF w/ICSI- Feb. '14 EPP/lupron/antagonist: Estrace, lupron, HGH, Gonal-F, Menopur, HcG, PIO, lovenox, doxy/dex.=21 retrieved, 16 mature, 15 fertilized!! 5dt of 1 blast/ 6 frozen. BFP! Beta 1 9dp5dt:83.9 Beta 2: 11dp5dt: 145.2 Beta 3 14dp5dt: 497 Please be our sticky rainbow baby!
I've researched this and also discussed it w my dr. It helps line up all the antral follicles prior to the beginning of your cycle so there isn't a dominant follicle that leads when you start stim meds. In other words, it keeps them quiet and all the same size so they all respond at the same rate. This is how they achieve many dominant follicles for ivf.
Married September 5, 2009
TTC #1 since December 2010 DH (33): Perfect Me (33): All tests normal; Unexplained IF IUI #1 July 2012 - Chemical IUI #2 - #6 - All BFN IVF #1 (New RE) March 2014 - Antagonist Protocol - 15R, 6F, transferred 2 5day embies -BFN
Re: Estrace
Did you go to IU Bloomington?
12/12: c/p
4/13: c/p
8/13: Started seeing RE; DX: Unexplained IF, RPL testing normal, SA perfect.
Oct - Dec '13: Clomid 25 mg + Ovidrel + IUI = BFN
2/14: IVF #1 Gonal F + Menopur + Ganirilex + Lupron trigger w/ HCG boost= 28R, 11M, 5F. 5dt 4BB, 1 frozen 4BB. BFN
4/14: IVF #2 Saizen, Gonal F, Menopur, Ganirilex = 20R, 10M, 10F. 5dt of 2 4AB, 2 frozen 4BB. +HPT 4dp5dt, Beta 4/26
found out at 20 weeks that baby B went to heaven
11/12/14 Baby girl arrived
FET (1-24-16) Grade A early morula
BETA #1 300 p4. 11.1
BETA#2 1300
u/s d 1 tiny babe
10/7/16 another sweet baby girl
4/18 SURPRISE + HPT
Beta #1 6 weeks 16,202 p4. 13.2
TTC #1 since June 2012
Me (28) - DOR (AFC <10, undetectable AMH, >10 FSH), homozygous E429A MTHFR
DH (29) - MFI low count and morphology
September 2013 IUI#1 - Clomid + Trigger + IUI = BFN
October 2013 IUI#2 - Letrozole + Menopur + Trigger + IUI = BFN
Nov 2013 IVF/ICSI #1 - Protocol: BCP prep, high doses Menopur and Bravelle (12 days), ganirelex
Results: 5 retrieved / mature, 4 fertilized, 1 arrested and 3 complex abnormal after day 3 PGS = Cancelled after ER
Jan/Feb 2014 IVF/ICSI #2 - Protocol: Estrogen priming, high doses Menopur and Bravelle (11 days), microdose lupron
Results: Cancelled after 11 days of stims due to low response and E2 levels
Feb 2014 IVF/ICSI #3 - Protocol: No prep, low dose Menopur (6 days), ganirelex, Bravelle booster with trigger
Results: 1 retrieved / 0 mature = Cancelled after ER
Officially moving on to embryo adoption! We used and love Embryo Adoption Services of Cedar Park
October 2014 FET #1 - BCP/Lupron/Estrace/Prometrium, transferred 2 of 4 from match #1, BFN
December 2014 FET #2 - BCP/Lupron/Estrace/Prometrium, transferred 2 of 4 from match #1, BFN
March 2015 FET #3 - BCP/Lupron/Estrace/Prometrium, transferred 2 of 6 from match #2, BFN
May 2015 FET #4 - BCP/Lupron/Estrace/Prometrium, lost 2 to thaw, transferred 2 of 6 from match #2, BFN
October 2015 FET #5 - Natural cycle, lost 1 from match #3 and 1 from clinic backup to thaw, transferred 1 backup, BFN
February 2016 FET #6 - Natural cycle, transferred 1 from match #4, B FREAKING P!
Beta 1 = 162, Beta 2 = 316, doubling just over 48 hours
Male Factor (severe oligospermia)
TTC since 2008
Dh:34, no issues. Me:31, Endo, slightly hypothyroid, deformed ovary, paracentric inversion.
4 Gonal-F, Cetrotide, HcG, Crinone +TI cycles= all BFN
Lap in 2012 to remove large unresolving cyst discovered endo and double lobed ovary.
6 Gonal-F, Cetrotide, HcG, Crinone IUI cycles= All BFN,
1st IVF w/ICSI- June '13 Antagonist: Gonal-F, Menopur, Ganirelix, HcG, Estradiol, Crinone= 7 retrieved, 4 mature, 1 unfertilized, 2 abnormally fertilized, 1 normally fertilized. 2DT of only embryo and our miracle BFP.
Our beloved baby boy was born sleeping Oct. 13, 2013 due to pROM/IC/Uterine infection.
2nd IVF w/ICSI- Feb. '14 EPP/lupron/antagonist: Estrace, lupron, HGH, Gonal-F, Menopur, HcG, PIO, lovenox, doxy/dex.=21 retrieved, 16 mature, 15 fertilized!! 5dt of 1 blast/ 6 frozen. BFP! Beta 1 9dp5dt:83.9 Beta 2: 11dp5dt: 145.2 Beta 3 14dp5dt: 497 Please be our sticky rainbow baby!
It's twin girls!! Born on 11-2-14!
Great..moody and pimply..Just what I wanted! LOL
DH (33): Perfect
Me (33): All tests normal; Unexplained IF
IUI #1 July 2012 - Chemical
IUI #2 - #6 - All BFN
IVF #1 (New RE) March 2014 - Antagonist Protocol - 15R, 6F, transferred 2 5day embies -BFN