Question about testing and protocols *loss mentioned

overwhelmed29 · February 2014

I know that every RE is different but I'm just pondering some thoughts. After my failed Ivf, I met with my RE. only to feel rushed out of his office. He just said, there's nothing wrong, ill get pregnant. We'll just transfer two this time. I felt rushed and did not get to ask much.
I had the initial testing for Ivf but I've never been tested for any implantation dysfunction issues or any autoimmune issues. I only had one pregnancy and it was a blighted ovum. I read that it can be the result of an implantation issue. I was just curious to see if anyone has been tested for this and when you had it done. I am scheduled for a FET on 2/19 and I don't know what the testing consists of or if it's too late to have it done.

katib77 · February 2014

I am sorry for your loss. But your RE is following a fairly normal track if you've had the one loss and it being a blighted ovum. You shouldn't be concerned with implantation or autoimmune when that has nothing to do with your last loss. Usually autoimmune testing is done if there indications or multiple loss where there is no other obvious cause. And if your FET is next Wed, I would say it is late to throw testing into the mix.

I know it is hard and you want all your bases covered...but sometimes it really does just come down to bad luck this far. FET stats are great esp if you have a good frost embies. Try to feel positive moving forward a nd good luck.

Twinkie0612 · February 2014

I am going to disagree with katib77, which I don't usually do. My RE ordered some immunological testing after IVF #1, which was canceled before transfer because our embryos stopped growing. Nothing in IVF #1 indicated that we needed testing, but my RE wanted to cover all of our bases before we paid for another IVF cycle OOP. I am glad we did, because my blood work did show slightly elevated NK Cells, so Intralipid infusions were added to my protocol. We have now done 3 IVFs, with no success so we obviously have more issues than just the NK Cells.

I think the big factor for my RE ordering the testing early is that my clinic is pretty big on diagnosing implantation dysfunction disorders.

overwhelmed29 · February 2014

@twinkie0612,
Is it a blood test to check? Do you recall how long it took to get the results back? We're also completely OOP.

Twinkie0612 · February 2014

My RE ordered two blood tests, one for APA (Aminophospholipid Anibodies) and one for Natural Killer Cell Assay. It took a few weeks to get back because it was sent out to a third party lab. As a warning, the tests aren't cheap. I think for the two tests, my bill was around $450 and that was with a self pay discount.

overwhelmed29 · February 2014

Oh wow, I assume it isn't covered my most insurance? My insurance covers testing just not anything toward a treated cycle. Thank you so much for the info and I'm so sorry to hear about your failed cycles. IF totally sucks.

pblge · February 2014

katib77 is right that it's too late for your FET on the 19th. Hopefully this FET will work for you so that you never have to worry about this!

missmarypoppins · February 2014

I agree with PPs that it may be too late to get the results by the 19th. My clinic said it takes 2-3 weeks, 18 days later and I haven't gotten my results back.

My RE strongly reccomended the whole RPL panel after our failed IVF. And I resisted, because I thought it seemed like a waste of money. In the end we went for it because I don't want to throw away another cycle if there's some underlying issue that's affecting implantation. My REs exact words were "you had two perfect embryos, perfect lining and perfect hormone levels, so either its bad luck or there's something we're not seeing on the surface."

Also on the time issue, we almost didnt have it done because the results wouldn't be in in time. But our cycle has been delayed 12 days because of my progesterone so now the results will be in on time. You just never know what's going to happen. Good luck!

missmarypoppins · February 2014

Also, id be seriously pissed if my RE made me feel rushed after a failed IVF cycle! He should be taking his time to answer all of your questions and really make an effort to examine what could have gone wrong. But that's just my two cents!

Carol77B · February 2014

I had my follow-up for a failed IVF (my first, too) and he said pretty much the same thing- nothing was wrong, just didn't happen, but because we didn't get a lot of embryos we would try different meds to work on that (Lupron). I asked about the steroids some of the women on the board are on to help with implantation and he said that he didn't think it was worth the potential side-effects and that one failed IVF didn't indicate an implantation issue. If #2 also produces good embryos and we don't get pregnant, he will try and get us into a study for an investigational drug to help with implantation which would cover the costs (I believe he said of the whole IVF cycle) I've never been offered any of the other tests mentioned and we are OOP.

overwhelmed29 · February 2014

Thank you all so much for taking the time to reply to me. I am going to ask my RE. I rarely see him, only when I schedule apts with him. He doesn't do email or phone calls, everything goes through the nurses. I assumed that I didn't have issues with implantation because I got pregnant before but after reading stuff, I cannot rule it out.

@Carol77b, My Re has me on baby aspirin starting on day 4 and I will start an antibiotic and steroid about 3 days before the FET.

Oh yeah,

HAPPY MONDAY!!

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