Infertility

CoQ-10 Has anyone taken it & did it do anything?

Hello,  I am about to start cycle number 2 & have been recommended to add CoQ-10 supplement to my med's along with a higher dose of GonalF (FSH) from 225 to 300 twice daily with my microdose lupron. 

Has anyone used the CoQ-10 supplement?  How did it work/help?

Re: CoQ-10 Has anyone taken it & did it do anything?

  • I did for IVF #2.  I took to ubiquinol form.  I don't know if it helped, but we went from 6R 5M 3F 0 made it to transfer for IVF #1 to 8R 7M 5F and transferred one blast for IVF #2.  We also increased my follistim and added Ganirelix instead of lupron around CD 1 ( I still used lupron for down regulation).

    imageimageimageimageimage

     

    image

    TTC #1 since August 2011

    My Blog

    September 2012: Start IF testing

    DH (32): SA is ok, slightly low morph, normal SCSA  Me (32): Slightly low progesterone, hostile CM, carrier for CF, Moderately high NKC, High TNFa, heterozyogous mutated Factor XIII, and +APA

    October 2012-May 2014: 4 failed IUIs, 3 failed IVFs, and 1 failed FETw/donor embryos

    November 2014: IVF w/ICSI #4 Agonist/Antagonist with EPP and Prednisone, Baby Aspirin, Lovenox, and IVIG for immune issues.  Converted to freeze all due to lining issues.  2 blasts frozen on day 6!

    January 2015: FET #2 Cancelled due to lining issues

    April 2015: FET #2.1


    PAIF/SAIF Welcome!

  • Loading the player...
  • CoQ10 is an antioxidant.  I *think* the theory is that as we age, we have less and less CoQ10 in our cells.

    My acupuncturist recommended that I take 300 mg 2x a day with food (it is fat soluble).  I've been taking it for almost 3 months.  I'll see how my eggs look in a week or so (I hope.  FX!).  Some people take the more active version of it, ubiquinol.

    It doesn't seem to have many side effects. 


    The one side effect I had when I first started was constipation.  It did get better over time.

    imageimageimageimageimage

     

    image

    TTC #1 since August 2011

    My Blog

    September 2012: Start IF testing

    DH (32): SA is ok, slightly low morph, normal SCSA  Me (32): Slightly low progesterone, hostile CM, carrier for CF, Moderately high NKC, High TNFa, heterozyogous mutated Factor XIII, and +APA

    October 2012-May 2014: 4 failed IUIs, 3 failed IVFs, and 1 failed FETw/donor embryos

    November 2014: IVF w/ICSI #4 Agonist/Antagonist with EPP and Prednisone, Baby Aspirin, Lovenox, and IVIG for immune issues.  Converted to freeze all due to lining issues.  2 blasts frozen on day 6!

    January 2015: FET #2 Cancelled due to lining issues

    April 2015: FET #2.1


    PAIF/SAIF Welcome!

  • ****paif response****

    I added it in for IVF #2 and FET #2.2 My protocol for my second fresh cycle didn't change all that much but I did have more mature and retrieved, about the same fert rate and a better thaw rate so far (see siggy).

    I can't say taking it is what did it for us, but it doesn't seem to hurt us at all. I didn't have any s/e that I noticed.
    Me: 37, DH: 35 :: TCC since 2/11 SA: Perfect! CD3  HSG = Blocked Right Tube
    April- Femara 2.5mg + Trigger + IUI = BFN   May- Femara 5mg = CX - No Response on Left = BFN
    June- Femara 7.5mg + Trigger + IUI = BFN  August- Lap & Hysteroscopy = Blocked & Partially Blocked Tubes
    September- Femara 5mg = CX - No Response on Left = BFN  October- 100mg Clomid + Trigger + TI = BFN
    IVF # 1: Stims 11/30 ER 12/12/12! (10R, 10M, 8F, 2T, 6 F) :: Beta #1- 176  c/p @ 4w4d
    FET #1 February 26th :: Lost 4 to Thaw, Transferred 2 = BFFN
    IVF # 2 Stims 5/10 ER 5/21 (15R, 13M, 13F, 2T, 7F- 6d3 & 1d5) :: Beta # 1- 15 c/p @ 4w
    FET #2 Cancelled, Right Tube Developed a Hydro  8/28 Hydro & Scar Tissue Removed  Cleared for FET
    FET #2.2 Scheduled for September 20th
    2 Thawed, 2 Transferred! Beta #1- 96, Beta #2 906! :: EDD June 10th
    2015- 2 failed FET. We are done
    SURPRISE! BFP 8/8/16   EDD 4/1/17

     
    imageImage and video hosting by TinyPic

    Baby Birthday Ticker Ticker

    Pregnancy Ticker
  • I have been told that it could cause insomnia a bit like caffeine if taken too late in the day....But what I am really worried about is that all of the info I have found on line says that it needs to be taken 3 months in advance to have much of an effect & this is our last cycle with med's starting in about 10 days........so this supplement could be a little bit of a waste.
  • My husband took them as part of an attempt to improve his sperm analysis....now, it was one of a few things he was taking but the supplements did help! I think it has something to do with overall cell function in your body
    Our Novel of TTC:

    *Male Factor (low count and low motility), High Prolactin, and Polycystic Ovaries (March 2013)
    *Recurrent Miscarriage testing also revealed high anti-phospholipids & single MTHFR mutation. (Feb 2014) 

    *IVF (07/2013): BFP-Natural Miscarriage @ 5 weeks* <3 Madison Riley <3
    *FET #1 (10/2013): BFN
    *FET #2 (12/2013)- BFP-Missed Miscarriage at 8 weeks <3 Kyle Andrew <3
    *Chromosomes and Karotyping tests were both normal.We lost a healthy baby boy :(
    *FET #3 (04/2014) was cancelled after finding Chronic Endometritis
    *Miraculous BFP July 2014!! (I was taking baby aspirin and Cabergoline to stay regulated while "taking a break from TTC" and waiting to consult with a reproductive immunologist!!!) 

    Our healthy baby girl was born 03/10/15 thanks to daily Lovenox injections and baby aspirin. There are no words for how grateful I am for our rainbow baby. <3
  • *****PAIF Response*********

    I did the CoQ10 & DHEA regimen with my last cycle.  I dont think I'll ever know exactly what caused it...I think the total cocktail of meds....but I had MAJOR insomnia.  My brain would just not shut up so I could sleep.  It was awful.  

    I didnt end up with more eggs, and I had nothing to freeze, but I did get my BFP out of that cycle.  


    ****Siggy Warning****

    IVF Cycle #1 - 4/06/2013 -3dt of 2 embryos, nothing to freeze - BFN 
    IVF Cycle #2 - 7/18/2013- 3dt of 3 embryos.Froze one 3AA 6 Day Blast! - BFN
    IVF Cycle #3 - 9/15/2013 - 3dt of 4 embryos, nothing to freeze - BFP!!!
    10/7 - +HPT - Beta #1 10/10 - 72, Beta#2 10/14 - 518,Harmony 21 @ 12 weeks shows one very healthy little BOY!!


    imageimage

    Baby Birthday Ticker Ticker
  • I have been told that it could cause insomnia a bit like caffeine if taken too late in the day....But what I am really worried about is that all of the info I have found on line says that it needs to be taken 3 months in advance to have much of an effect & this is our last cycle with med's starting in about 10 days........so this supplement could be a little bit of a waste.
    I started the CoQ10 & DHEA 14 days before CD 1.  There is no clear literature that suggests that 3 months is the magic number.  My husband is a neuro-physiologist and spent a great deal of time investigating the "cocktail".  The evidence both for/against it is inconclusive but there have not been detrimental side affects.   

    I'll never know if it was contributing factor to the success of that cycle or not...
    ****Siggy Warning****

    IVF Cycle #1 - 4/06/2013 -3dt of 2 embryos, nothing to freeze - BFN 
    IVF Cycle #2 - 7/18/2013- 3dt of 3 embryos.Froze one 3AA 6 Day Blast! - BFN
    IVF Cycle #3 - 9/15/2013 - 3dt of 4 embryos, nothing to freeze - BFP!!!
    10/7 - +HPT - Beta #1 10/10 - 72, Beta#2 10/14 - 518,Harmony 21 @ 12 weeks shows one very healthy little BOY!!


    imageimage

    Baby Birthday Ticker Ticker
  • SAIF! Siggy Warning!

    I am currently on both dhea and cq10 for ivf # 2 in January. I can agree with the horrible insomnia but if I take my last dose (3x day) before 5:30pm I'm able to sleep at night. I have poa so hoping this helps us with more/better eggs.
    Baby Birthday Ticker Ticker
  • Thank you, everyone.  We are going to try CoQ10at 200 twice daily in the Ubiquinol form.  I hope it helps, but even if the cycle is a success I am not sure if we will ever know what really helps...
This discussion has been closed.
Choose Another Board
Search Boards
"
"