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IVF newbie here..

My RE recommends me to have an IV cocktail the day of the transfer.  This is due to recurrent miscarriage. It is not covered under any insurance plans.  I understand why he recommends it but I also feel as though he is padding his pockets. I believe it is called, Intralipids.  WWYD?  OOP cost is $180. 








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Re: IVF newbie here..

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    I'm a newbie too. What is it supposed to do?

    TTC since April 2012

    BFP #1, 10/03/2012 - EDD 6/15/2013 - MMC 11/15/2012 - D&C 01/04/2013

    BFP #2, 04/06/2013 - EDD 12/17/2013 - MC 04/19/2013

    6/12/2013 Diagnosed with Balanced Translocation (12 & 16)

    IVF #1 with PGS: 10/2013: Canceled 9/27/2013 for issues with genetic lab

    IVF #1.5 with PGS: 11/16/2013: Canceled. 11 eggs retrieved, 9 mature & 9 fertilized, all unhealthy embryos

    IVF #2: 1/22/14: Canceled. 16 eggs retrieved, 14 mature, 7 fertilized, all unhealthy embryos

    IVF #3 with PGS: 5/10/2014: Switched to FET in July. 10 eggs retrieved, 9 mature, 8 fertilized, 2 healthy embryos!

    FET #1: 7/31/2014: Transferred 2 nearly perfect (6AA, 6BA) healthy embryos- BFFN

    Laproscopy: 10/2014: Healthy uterus

    IVF #4: 12/8/2014: Canceled. 17 eggs retrieved, 15 mature, 10 fertilized, all unhealthy embryos



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    I cannot speak to your specific question but I did want to say that if you feel as though your RE is recommending things in order to 'pad his pockets' then I would find another RE. This person is in a position that you need to trust and if you don't trust them, they are not the right match for you.  IMHO.

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    Did you ask your RE why he is recommending this treatment? (Besides rpl). Have you done any research into it? If you don't feel comfortable with the treatment or you think he's just padding his pockets opt out of the treatment.

    TTC#1 since April 2011
    IVF#1 July 2012 5R, 3 made it to blast, sET c/p
    FET#1 Aug 2012 2 blasts transferred BFN
    IVF#2 Oct 2012
    16R/6M/6F/2-8 cell grade 1 transfer
    Beta 1-237.9, Beta 2-566, Beta 3-8657
    US 6w3d shows one baby w/ HB 115
    US 7w1d no more heartbeat/ D&C 11/30/12 normal karyotype
    IVF#3 Mar 2013
    6R/4M/4F 1 compacting and 2-8 cell transfer
    ectopic pg MTX given 3 month break from TTC

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    There are a lot of studies surrounding intralipids helping rpl. Our RE is having me tested for NK cells before using intralipids. Some RE's just do intralipids, hoping it helps with implantation. My understanding (and maybe someone else knows more) is that if you have active NK cells and intralipids help, you need to have infusions every 3-4 weeks through the first tri and sometimes a little longer. Your RE isn't completely crazy for suggesting it. There are more and more RE's seeing the research behind it. Some RE's happen to think it's not necessary and some are a little more open to the idea. However, for intralipids to work, you need the infusion one week before ET. (At least that's what my RE suggests if my blood work comes back + for NK cells)

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    1st u/s @6w5d: Baby A hb 124, Baby B hb 127 (Both measuring perfectly!)

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    **siggy warning**
    Intralipids are used for elevated nk cells (everyone has nk cells, its the level of them that should be concerning). I use ivig for elevated nk cells and elevated cytokines. We attempted to control my level w prednisone first. When that didn't reduce it enough, I had an infusion the day before et. My ri suggests the infusion w in a week of et. Then about a week after the infusion they checked my levels again. They are still elevated but not as much so we increased my prednisone dose to buy me time till another infusion. I will get infusions every 4 weeks throughout my pregnancy depending on what my labs say.

    If you haven't been tested, I'd suggest asking for that. Fwiw, this was the first cycle we did an infusion and it was our first bfp. I'm under the care of Dr Kwak Kim in addition to my re. If you can see a reproductive immunologist, I'd recommend it.
    "Everything will be alright in the end. So if it's not alright, it is not yet the end."
    Me:29 DH:29  TTC since 1/11 Dx: unexplained IF/early DOR/immune issues 
    Feb'12- July'12-testing(all clear minus slight arcuate ute), 3 IUI with clomid all BFN
    8/30IVF#1 Antagonist protocol- ER 9/11-8R, 7M, 5F. 
    ET 9/14 2 embies transferred. 1 10cell Grade 4, 1 8cell Grade 4. No frosties. BFN
    IVF#2 Antagonist protocol plus baby aspirin- ER 12/5-16R, 12M, 8F!
    ET 12/10 5dt! 1 fully expanded blast & 1 early blast. No frosties. BFN
    3/13 hysteroscopy & polypectomy, Consulted w Dr. Kwak-Kim.  
    DX: High NK cells, cytokines, DHEAs& PAI1;  hypothyroid, +APA, restricted bloodflow
    7/13 IVF#3 Long lupron protocol with PIO, Crinone, Prometrium, and vivelle
    (plus synthroid, metformin, baby asa, metanx, PNV, Vit E, D, calcium, fish oil, CoQ10, IVIg infusions and lovenox per Dr. Kwak-kim)
    ER 7/19 14R, 11M, 9F(4 natural fert, 5 with ICSI)
    ET 5dt 7/24 2 fully expanded blasts.  SURPRISE 3 FROSTIES!!!
    Beta #1 8/2 335!!!! Beta #2 829!!!  1st u/s 8/14 showed TWINS!!!!!
    11/11: TEAM PURPLE!!!!!
    3/21/14-L&W born at 37w via csection

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    megs3084 said:
    **siggy warning** Intralipids are used for elevated nk cells (everyone has nk cells, its the level of them that should be concerning). I use ivig for elevated nk cells and elevated cytokines. We attempted to control my level w prednisone first. When that didn't reduce it enough, I had an infusion the day before et. My ri suggests the infusion w in a week of et. Then about a week after the infusion they checked my levels again. They are still elevated but not as much so we increased my prednisone dose to buy me time till another infusion. I will get infusions every 4 weeks throughout my pregnancy depending on what my labs say. If you haven't been tested, I'd suggest asking for that. Fwiw, this was the first cycle we did an infusion and it was our first bfp. I'm under the care of Dr Kwak Kim in addition to my re. If you can see a reproductive immunologist, I'd recommend it.
    Is that really pronounced "Doctor Quack"? I thought the urologist being named Dr. Seamen was funny. :)   (I'm still on drugs and a bit loopy)
    ***WARNING***

    TTC Since 12/2008;  DH: 32, Azoospermia     me: 33, DX during IVF #4: Low AMH (Normal FSH) / SER due 
    to IVF Meds (causing failure to fertilize) Recent DX: Hashimoto's, Lupus Anticoagulant, White Blood Cell Disorder 
    High ANA, ATA, & APA, PAI-1 Heterozygous= blood clotting disorder; connective tissue disorder 
    IVF w/ ICSI #1 2/2011     IVF w/ ICSI #2 5/2011    IVF w/ ICSI #3 12/2012   *New RE* IVF w/ ICSI #4  5/2013
    IVF w/ ICSI #5 8/2013 (Natural Cycle- No drugs)- One follicle->one blast. CCS normal. FET 9/10- 6BB blast. m/c @ 5w
    IUI #1 12/23- BFN  IUI #2 Cancelled (ovulated during AF)  Prep:CoQ10 (300 mg); DHEA (25 mg); Melatonin (3 mg), Folgard 2.2, Metformin 500 2x, Levothyroxine 50mcg, Aspirin 81mg w/ calcium, B12,  Vit. D 4000 & Prenate Elite Daily; Cabergoline 1/2 pill 2x week-  Cycling: Estrace Priming; Prednisone 10mg, Lovenox 40mg 2x,  Femera & Menopur   
    IUI #2.1 6/30 & 7/1. 1st Beta: 90 (7/15); 2nd Beta: 226 (7/17); 3rd Beta: 766   EDD: 3/23/2015

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