Infertility

Attrition rate during growth phase? -IVF

Hi Ladies,

 FET #1 scheduled for the end of the month and stressing myself out during the wait.  Google's not helping much.  We froze all fertilized eggs ER day so I don't know how many will make it to the Blastocyst day 5 for transfer.  

Anyone with stats on an average percentage lost during growth or care to share their own experience?   Thanks

Re: Attrition rate during growth phase? -IVF

  • I haven't done FET, but when we discussed a freeze all, our RE stated that 97% will survive thaw and an average of 1/3 of those make it to blast. But, that depends on lots of different things too, like quality of the ones you froze, etc. Even though we didn't end up doing a freeze all, we did have exactly 1/3 make it to blast. So, that part was correct for us. But, it really only takes one rockstar!!

    BabyFruit Ticker

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    Beta #3 (21dp5d5): 8,172. Wow. It seems this is actually working. Shocked beyond belief.

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  • Mine were not frozen until day 6, but I was given a 95% survival rate for those. 

    I am not sure how freezing on day 1 will change things though. I had 5 fertilize, and if you include the 1 I transferred it would have been 3 out of 5 making it to day 5 and then freeze. So I guess  for me it was 60%. 


    Me: 33 DH: 32 SA#1 low count (6mil) SA#2- now in IUI range!(30mil) Dx:MFI
    11/1- IUI#1,12/1- IUI#2, 1/2- IUI#3 all BFFN
    IVF#1. Long Lupron.ER 3/8 10R,4M,5F. ET 3/3-one 1AB, 2 frosties 5dp5dt-BFP!! Beta 3/25-794 Beta 3/27- 1794
    First u/s 4/8 saw hb. 4/22 missed mc 8w3d. d&c 4/26
    FET #1- bcp start 6/9. ET 7/12. 2 perfect blasts.5dpt-BFP!! 
    Beta 7/24 -1,239!! Beta 7/26- 2569 Beta 7/29- 7120.  U/S 8/7 hb 118! U/S 8/14 hb 143! U/S 8/20 hb 170. Graduated!! Stick baby stick! 


  • Most clinics have a 90 % or better rate of the thaw. My clinic only freezes blasts.  I did a fresh cycle because all my embryos Arrested on my third ivf. On the June fresh cycle I had 11R,11M, 9 F. Of the 9, 7 made it to blast by day five. Two transferred and five expanded blasts frozen. That is a 63% rate of success. I would never have guessed we would be so successful this time around. Don't  get discouraged if there are some road blocks Along the way. My hope for you is that your journey is short (unlike mine of four years). GL.
    Five IUI 's and two 3 day IVF transfers and two chemical pregnancies. Unknown to me at the time was that I was hypothyroid and had endometriosis. All that heartache and money and I would have never gotten pregnant. Time for new RE. New RE found the thyroid and endo. I had another 5 day transfer in April when all 7 embryos arrested on day four. Transferred three morali and didn't conceive. Thyroid function is excellent now. DH SCSA came back perfect. Now for IVF number four in June 2013. I had two perfectly expanded blasts put back and five frosties! I have never gotten this far! Now to wait for blood test on 6/26. My heart is In my throat! Please let this work, BFP with HPT 7 days and 8 days after transfer.
  • Thanks for the encouragement.  And JennySC34 FX for you tomorrow!
  • They really froze them on Day 0?  Usually it is day 3 or 5 that they freeze because they need at least day 3 maturity to have a good thaw survival rate.

    I would talk to your nurse to verify that it was a day 0 freeze and she should be able to tell you or find out for you what your clinic's thaw rate for day 0 freeze survival is as it does vary clinic to clinic!

    Good luck!

    Married: 7/2/11 TTC: 12/2011
    Me: 31, PCOS DH: 37, low morph and low counts

    4 medicated TI, 1 IUI+Femara, 1 IUI+GonalF = BFNs
    IVF #1 Lupron/GonalF (Dec 2012)= 30R, 21M, 21F with ICSI, 18 HIP frosties!!!
    FET in August 2013 

    http://i45.tinypic.com/21pym9.jpg

  • It might actually be day 1, either way ER was on Wed afternoon and when I went in for blood work Friday morning they were already frozen.  This is part of the research study I am in.  It's called Post Thaw extended Culture.  

    In case anyone was curios:   https://www.fertilitycenterlv.com/postthaw.html

     

  • I would be really surprised and quite frankly concerned if they froze all your embryos on Day 0 or Day 1.  I know different RE's have various protocols, but from all I have read and discussed with my RE, that really isn't standard protocol.  Most RE's freeze on Day 5 because they have the greatest chance of surviving thaw and turning into a successful pregnancy.
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