Infertility

If you did IUI w injects and then IVF

How much was your dose of FSH increased compared with the IUI cycle?

 My IUI started at 75 of gonal F, eventually increasing to 112.5. I got 4 mature.  My IVF is scheduled to start at 187.5.

I had a second opinion appt last week and the 2nd RE expressed concern about starting ivf at such a low dose esp, since I would have been on bcp for 2 months prior plus lupron. She thought I should be on a much higher dose "to shock the ovaries to wake up".   I asked my RE about it and she thought for a second then said "nope, that dose is fine for you".  DH is now concerned that the second opinion RE is right.

I know everyone's protocol is different but would be interested to know what your starting dose is.

image
TTC #1 since Jan 2012
IVF March/April 2013

Re: If you did IUI w injects and then IVF

  • I was on Follistim at 75 for 5 days when I did IUI.  I responded well on my first time with the stims so they said I could transfer to IVF. (I didn't)  So I was a little shocked when I was put on 450 Gonal F for my first IVF.  My RE said that they wanted to go with the most aggressive approach because of my age.  Well sure enough they had to knock my dosage down to only 150 and I stimmed for only 8 days--They are afraid of OHSS.  

     

    So if you responded well when you did IUI, I wouldn't sweat it too much.  They can always increase your dosage if you aren't doing well.  Think of all the money you will save on medications!  :)

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  • It's really hard to say which is the 'right' answer at this point.  There are lots of different opinions and approaches on how to do IVF - and everyone's own body reacts differently.    So its hard to know how your body will respond at this point.
     TTC #1 since 6/09
    Dx: PCOS and MFI
    3 IUIs, 4 IVFs = BFFN
      3rd RE: IVF #5/FET = BFP
    14dp5dt=1170 16dp5dt=2573

    1st u/s=
    TWINS!
    It's a Boy and a Girl!

    Born at 34w3d! 
     

  • imagehootie123:
    It's really hard to say which is the 'right' answer at this point.  There are lots of different opinions and approaches on how to do IVF - and everyone's own body reacts differently.    So its hard to know how your body will respond at this point.

    I know. I'm really just curious on what other people's RE put them on, obviously the response could be different iui v ivf.

    image
    TTC #1 since Jan 2012
    IVF March/April 2013
  • imagenoelcallum:

    imagehootie123:
    It's really hard to say which is the 'right' answer at this point.  There are lots of different opinions and approaches on how to do IVF - and everyone's own body reacts differently.    So its hard to know how your body will respond at this point.

    I know. I'm really just curious on what other people's RE put them on, obviously the response could be different iui v ivf.

    The range for starting is about 150IU on the low end and 600IU for people on max doses.   I've started at from 200IU to 400IU depending on my protocol.

     TTC #1 since 6/09
    Dx: PCOS and MFI
    3 IUIs, 4 IVFs = BFFN
      3rd RE: IVF #5/FET = BFP
    14dp5dt=1170 16dp5dt=2573

    1st u/s=
    TWINS!
    It's a Boy and a Girl!

    Born at 34w3d! 
     

  • Don't forget that many RE's up a dosage during stims if you're not responding in the way they expected.

    I think it seems like a good starting point and could easily be upped if needed.

    BzeetyD = 38, Mr. BzeetyD = 44 together 12/02 married 9/08
    TTC #1 since 1/10
    DX: Unexplained/??? MFI issues

    Our lil' lost sparks:
    5w3d loss 7/30/10 - EDD March 2011
    8w loss 4/15/11 - EDD November 2011
    8w3d loss 8/2/12 - EDD March 2013
    4w c/p loss 10/29/12 - EDD July 2013

    Long story: trying on our own + testing testing testing with 6 rounds of Clomid, more testing, injectables + TI, laparoscopy - one tube blocked, 2 IUIs with Follistim...BFNs.
    RPL testing all normal, Karyotyping normal

    Moving on to IVF.

    IVF #1 April 2012 = BFN, IVF #2 June 2012 = BFP. U/S 7/23 = saw heartbeat but measuring behind. Follow up U/S on 7/30 - no heartbeat. D&C 8/2. Trisomy 12. IVF #3 Oct 2012 = Chemical Pregnancy

    Phone consult with CCRM on 12/12/12 - ODWU 1/4/13 - both tubes clear(!) - AFC 24, AMH 3.2, FSH 9.6, LH 5.4, E2 25. DH has high frag rate but improved!
    IVF #4 March 2013 CCRM. EP protocol w/ Menopur, Gonal-F & Dexamethasone. ER 3/29 & IMSI, PICSI. 43R 13M 10F 6blasts bio'd. CCS testing reveals 3 normals!!!
    FET 5/31/13 of 1 4AA blast - thawed and expanded. 4dp5dt BFP.
    Beta 9dp5dt = 181, 11dp5dt = 427. 1st u/s showed a healthy heartbeat! EDD 2/16/14

    After 4 years of hoping and heartbreak, our sweet little bean was born on 2/19/14
    We are so in love with her.

    "I'm not telling you it's going to be easy, I'm telling you it's going to be worth it."

    Everybody is welcome!!!
  • We haven't done an IVF cycle yet, but my RE tends to use the lower doses with most of her patients. Her partner in the clinic on the other hand, tends to use higher doses right off the bat. The other doctor gets more eggs, but mine tends to have a higher percentage of mature eggs. Their pregnancy rates are the same though.

    So, no personal experience yet, but just wanted to throw out what my doctors thinking on it was!

    image imageimage
    image

    ***EVERYONE WELCOME***
    TTC #2 with assistance since 03/11
    Me: 33, Autoimmune (Hashimotos and FMS/CFS)
    Treated with Synthroid, acupuncture, TCM and supplements
    DH: 33, MFI (very low on all counts, high antibodies, hemochromatosis)
    Many treatments tried, none successful

    IVF/ICSI #1 05/14 - EPP/Antagonist, Gonal-F and Luveris, 18R, 14M, 13F - SET of 1BC, all arrested on day 5 - C/P
    Genetic testing = normal, DNA Frag = excellent
    IVF #2 03/15 - Long protocol with Suprefact, Gonal-F, and possibly Luveris, adding in PICSI
     
  • That does seem a little low. I was on 125iu of follistim for my IUI cycle and 300 for ivf cycle.
    image



    Me 28 DH 30

    After 4+ years TTC

    FET #2 = DS Madden Jeffery <3 July 29, 2014 <3
  • With IUI i was on 75 iu follistim for one cycle and then 150 for another cycle and got one-two mature follicles (although my E2 never got higher than 130-150, so who knows if they were actually mature eggs in them).  with my first IVF i did 300 follistim daily, stimmed for 10 days and got 3 mature eggs.  With this IVF I am starting again with 300 daily (150 morning 150 afternoon).  

    Good luck to you! 

    Me (37) DH (39); PCOS changed to Unexplained, changed to DOR in 2012 (finally a correct diagnosis!); 
    Started TTC 2009 with RE after 6 months.  
    Clomid + Trigger x2; 
    IUI + Femara x1,
    IUI + Follistim x2;
    IVF #1 (MDL) February 2013- BFN.
    IVF #2 (antagonist) May 2013, First BFP of my life. 
    Identical twin miracle BOYS (!!) headed our way- due date is technically 2/4/14 but c section is scheduled for 1/7! 


    BabyFetus Ticker image
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