PIO Shots?! — The Bump
Pregnant after IF

PIO Shots?!

When did you ladies get to come off PIO?? I'm 6 wks on Saturday and still having to take them... ugh.  I dread it every morning!  I'm just ready to be done with them!

All Welcome

Me: 29 DH: 30

IF DX Endo Stage III/IV SA: PERFECT!

7/16/2011 Married handsome hubby!
9/2012 Lap/Hystercopy DX w/ Stage III endo
Bilaterial Uterine Suspension/D&C/HSG
HCG/D&D on R/L ovaries/chromaltubation/Uterine Polyp
10/2012 RE consult. DX move straight to IVF
IVF #1 11/27/2012
IVF #1 Cancelled for Low Response and Converted to IUI #1 --- BFN

IVF #1.2 BCP 12/29 Stims 1/21 w/ New Protocol - Antongonist (225 Menopur, 150 Follistim, & Ganirelix)
ER 2/2/13 11R,9M,8F -- ET 2/7/13 2 Beautiful Perfect Blasts/5 made it Freeze! -- 2/12/12 +HPT -- 2/14/13 Beta #1 71 -- 2/18/2013 Beta #2 521 YAY! Let this be our take home baby!

4/21/13 Massive Hemorrhage from unDX placenta previa.  Bed Rest for 7 months.

10/17/13 Gave Birth to our 8lb 2oz baby boy! 

8/30/15 Started Meds for FET schedule on 10/13/15

10/13/15 TX two great blasts.  Beta scheduled for 10/22/15

Re: PIO Shots?!

  • My last one will be the first day of week 7 (next Wednesday). I can't wait!!
    Me - 35 DH - 37 SD - 10
    Married 10/8/2011
    Started TTC July 2011. Infertility workup July & August 2012.

    DH - all clear. Me - Unicornuate Uterus discovered at HSG 8/16/12. Referred for IVF 8/28/12. Approved for IVF Warranty Program 10/2/12. Laparoscopy 11/1/12 - removed right rudamentary horn, both tubes, left ovarian cyst and endometriosis.
    Given all clear for pregnancy after 1/1/2013.


    IVF cycle 1 starts 1/19/13!

    12 eggs, 7 mature and all 7 fertilized - 2 Frosties!!

    5 day SET 2/4/13 - Beta 2/13: 86 & 2/15: 186 BFP!!!!

    EDD: October, 23, 2013



    Blog: http://journeyofaplayer.wordpress.com/





    [IMG]http://i47.tinypic.com/sg4uir.jpg[/IMG]
  • I did at 10 weeks.  My RE gave me the option around week 8 of going on suppositories-but those are so messy that I actually preferred the shot.

    You'll be done before you know it!

    TTC since 5/2010
    DX with Diminished Ovarian Reserve - AMH of 1.1 - 7/2011; AMH of .42 8/2012
    BFP 9/1/10-M/C confirmed 9/8/10-Methotrexate 10/6/10
    IUI #1 (w/clomid)-9/5/11-BFN ; IUI #2 (w/clomid)-10/5/11 - BFP - 11/1/12-No sac seen; 11/2/11 and 11/9/11-Methotrexate 
    IVF #1- ER 2/2; ET 2/5;-Two 8 cell embryos transfered = BFFN
    Surprise BFP - 5/7/12
    U/S on 6/8/12 - H/B at 128 BPM; U/S on 6/14/12 @ 9wks-No H/B-D&C on 6/17/12
    IVF 2.0- ER 10/17; ET 10/20-One 12 cell, one 10 cell and one 8 cell embryo transfered
    BFP!   11/16/12 U/S- Two nuggets with perfect heartbeats! EDD 7/10/13

     

    5/31/2013- My miracles arrived at 34w2d!  Welcome to the world Harper and Nolan!Lilypie First Birthday tickers

    My Blog- http://waitingonaangel.wordpress.com/

    Image and video hosting by TinyPic

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  • MY RE says I have it until 11 weeks. I don't hate the shot itself as much as the aftermath. My backside is starting to REALLY hurt! :( Oh well, it's a small price to pay for a LO. I'm trying to remember that.

    ************ Signature/Ticker Warning ************
    Me (32) DH (36) - Finding our way to baby #1
    Me: POF/DOR - AMH <0.16, heterozygous c677t MTHFR, insulin resistant and gluten intolerant
    DH: Severe MFI

    12/2/11 - IUI #1- BFN 
    8/1/12 - IVF #1 - Zero response from max stims (600iu intramuscularly)
    My ovaries are just for decoration

    12/6/12 - Adopted five embryos that had been frozen for over ten years!
    2/11/13 - DEmbryo FET #1 Thawed four, sadly two didn't survive. Transferred two beautiful blasts. 
    2/16/13 - First BFP of my life @ 6dp5dt! EDD 10/30/13
    3/27/13 - After beta and u/s hell, no heartbeat ever detected. D&C at 9w1d.

    6/5/13 - Adopted four new embryos that had been frozen for seven years!
     
    9/12/13 - DEmbryo FET #2. Thawed and transferred two beautiful blasts
    9/17/13 - BFP @ 5dp6dt! EDD 05/31/14
    9/29/13 - m/c @ 5w1d. :(

    11/19/13 - DEmbryo FET #3. Thawed and transferred one blast from each batch. Wow!
    11/23/13 - BFP @ 4dp6dt! EDD 8/7/13
    Beta #1 @ 13dp6dt - 522  Beta #2 @ 16dp6dt - 1373 
    6w5d ultrasound showed one perfect baby with a beautiful heartbeat of 134bpm!

    Snowflake baby is a girl! 
    Our beautiful Snowflake girl arrived on July 22, 2014! 
     
     
    My embryo adoption blog: Wishing on a Snowflake
     
        image      image 
  • I know the feeling! I'm only 5w4d, but I'm on 2ml of PIO every day PLUS progesterone suppositories 2x/day. I haven't even asked, but I'm sure I still have several weeks to go.
    8/2010 IVF#1 (After many failed/cancelled IUI cycles) 3dt of 2 beautiful embryos - 3 frosties Betas-12dp3dt-215 : 16dp3dt-1175 : 20dp3dt-5088 - Baby Girl born at 38w6d on 5/10/11

    2/2013 FET#1 Transfer of 1 9 cell embryo and 1 7 cell compacted embryo. Beta #1 11dp3dFET - 37 Beta #2 13dp3dFET - 71 Beta #3 16dp3dFET - 297 Beta #4 20dp3dFET - 1300  - Blighted Ovum. Natural miscarriage followed by D&C 4/13

    5/2013 - Completely natural miracle surprise BFP!!! Beta #1 15dpo - 846 Beta #2 17dpo - 2141 - Baby Boy born at 38w0d on 1/19/14

  • image liz4paws:
    MY RE says I have it until 11 weeks. I don't hate the shot itself as much as the aftermath. My backside is starting to REALLY hurt! :( Oh well, it's a small price to pay for a LO. I'm trying to remember that.

    Exactly this.  They're doing weekly draws on me to check my levels, once my body takes over they'll let me off of them.  Right now even though it hurts, it's like my own little security blanket.  I know it's helping!

    Me- 32, DH- 32- TTC for 4 Years
    IUIs 1-6 BFN
    IVF #1= BFP- M/C
    FET- Beta#1: 69, #2: 482, #3: 1088, #4: 28,318, Ultrasound- 1 beautiful heartbeat
    It's a boy!

     BabyFruit Ticker

  • I may come off at 12 weeks if my progesterone is still very high. THere was a new study tht came out by the Vatican that IF people need more progesterone support throughout pregnancy they suggest it up to 16 weeks and then to continue testing to make sure the levels stay high enough.
    6 m/c
    Anovulatory cycles, increased Synthroid Diagnosed Sep 2010
    Natural cycle Dec 2010 BFP M/C 6 1/2 Weeks, D&E Jan 2011
    1 Clomid/Ovidrel BFN May 2011
    Natural cycle Aug 2011 BFP M/C 4 Weeks
    1 IUI Sept 2011 BFP M/c 7 weeks
    Provera Dec 2011 BFP M/C 3 Weeks
    DQ ALPHA HLA MATCH, High NK Cells Diagnosed Dec 2011
    IVF March 2012 BFP m/c 4weeks 5 days (IL, Prednisone)
    IVF#2w/DS July 2012 MEGA FAILURE BFN (IL, Dexamethasone)
    Diagnosed No real HLA Match, DQ Beta Triad, High TNF, Low NK Cells
    Oct 2012 Natural Cycle m/c 4wks (Lovenox, Prednisone) 
    Went to Beer Center- high tnf, low lad, implantation failure
    Nov/Dec 2012 LIT Treatment
    Dec 12 Humira
    Jan 2013 BFP
    Humira,LIT,Prednisone, Lovenox, IVIG, Baby Aspirin
    Miracle Born August 2013 Premature

    Yours doesn't have to be a sad story



    image
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    Lilypie - (ugiy)


  • I went off of them at 6.5 weeks but they were replaced with Crinone 2X a day.

    Honestly if I had my way I wouldve stayed on them until 8 weeks and then switched. I HATED the Crinone and also would've preferred to deal with the shot. Plus, the shot gave me better peace of mind.

    I was given the green light to come off the Crinone at 10 weeks, but naturally had almost a full box when they told me to just "finish what I had" so I was on it for almost 13 weeks.


    "I won't give up on us, even if the skies get rough, I'm giving you all my love, I"m still looking up."
    TTC #1 since August 2011 MFI Diagnosis - April 2012
    IVF #1 - July 2012 - Stims start 7/2, ER 7/12, 20 retrieved, 16 mature, 13 fertilized!
    ET - 7/17 - 1 blast transferred. Beta - 7/26 273, Beta 2 7/30 - 1143. Beta 3 8/6 - 11,597
    12/25 - Santa tells us "IT'S A GIRL!" EDD - April 4th

    Our Little Easter Bunny has arrived!

    Molly Mildred born 03/31/13


    TTC A Sibling....... FET #1 11/14/14, Transferred one beautiful blast

    Remaining four frosties arrested due to "embryologist error"

    Plllllleasssee stick little icicle.....Beta 11/23...BFN

    Starting ALL over with a fresh IVF cycle

    Stims start 11/28/14, ER December 10th, 13 eggs retrieved, 11 mature, only 4 fertilized 

    1 Blast Transferred on December 15th..... Beta Christmas Eve... Please Santa, bring me a baby!

    Beta #1 345.....Beta #2....750/ First U/S 1/13/15/HB 131....EDD 9/2/2015

  • My RE has you on PIO and Estrace until 12weeks.
  • 8 1/2 weeks, then suppositories until 10 weeks (although for my own comfort, I used them until I was 12 weeks)


    04/07/11- PCOS Diagnosis w/GYN. Put on Metformin (1500 mgs)
    04/25/11- 1st consultation with RE (Confirmed PCOS & Anovulation)
    05/09/11-HSG-All clear! 05/13/11-SA-Normal. Found out on 2/14/12, low Morph (1%).
    06/17/11-10 days of Clomid (100, 150) No response.
    07/10/11-03/20/12- 5 Injectable (Follistim) IUI cycles; 4 BFN, 1 C/P. (stims ranged from 11 days to 25 days)
    05/28/12-Diagnosed with Hypothyroidism. 75 mcg Synthroid.

    IVF with ICSI in June/July 2013 = BFP!. Beta # 1 = 123. Beta # 2 = 252. Due March 25th. Baby boy arrived March 27, 2013!

    FET #1 - 10/4/14 = BFP!! Beta #1 = 179. Beta # 2 = 499. Due June 22nd.

    Daisypath Anniversary tickers
    image


    image

  • My RE says PIO and Vivelle for the first 12 weeks....5.5 to go!!
  • They told me I could stop them right after my second beta b/c my numbers were so good, but I asked to stay on them through my 6 week/6 days ultrasound. I stopped them after that. I was sick of them, but honestly they made me feel reassured. 


    IVF #1 w/ ICSI 9/2012 (10M 6F), ET 9/24 (1 good pre-blast), BETA 10/4= BFN,
    IVF #2 Microflare w/ ICSI 12/2012 (19M 7F), ET 12/16 (2 Good blasts),
    BETA 12/26= BFP (356), BETA 12/28 (840) 2nd Ultrasound shows TWINS!!

    Baby Birthday Ticker Ticker
  • I'll be on them until 12-13 weeks. Hopefully I'll start weaning off at 9 1/2 or 10 weeks but I'll only be able to do that and fully stop if my levels look good.

  • I'll be 10 weeks when I'm done. I seriously CANNOT WAIT, we're running out of real estate and we had a bad one last week with a lot of blood and I almost passed out! Lol, I'm so done!
    Oct 13 April Siggy: Bunnies
    The 33 Most Important Bunny GIFs On The Internet


    image

    DS born on 9/30/13 from IVF #1.2!
      Lilypie - (xNS5)
  • Through 10 wks.... 8-12 seems to be the norm around here
    TTC #1 Since 4/2010, Cycle 30
    Positive for HLA-B27, I'm a mutant :p
    Testing - Me ok, gluten issue? DH - borderline count, low motility
    4/28/11 IUI#1 = BFP!(5/25), EDD 2/2/12 - m/c 5w3d
    7/3, 7/31, 9/25 - IUI#2-4=BFN
    IVF#1 - 1 blast = BFP!! (12/30), EDD 9/9/12, confirmed c/p 4w2d
    FET#1 3/2/12 - 2 blasts =BFP!! EDD 11/18/12, us#1 = twins! Confirmed m/c 5w6d
    4/20-surprise BFP and another c/p 4w2d
    FET#2 7/16/12 - 2 blasts = BFN
    FET#3 8/20/12 - 1 blast - BFP!! Beta #1-2=177, 354
    1st u/s 5w6d, one beautiful little HB :), 2nd u/s 146bpm
    baby girl born 5/10/13

    TTC#2 since 12/17/2014, Cycle 8
    Repeat Testing...FSH=12, AMH=3.8, AFC=28. 
    IUI#5 5/10/15- c/p?
    IVF#2 8/19/15 - cancelled due to cysts
    IVF#2 take two 10/2015 - 5 blasts frozen
    FET#4 12/11/2015 - BFN - 4 blasts remaining
    FET#5 2/18/16 - BFP!!!  Beta1-3, 126, 250, 745!!

    Image and video hosting by TinyPicLilypie Angel and Memorial tickers

    Tons of love and ((hugs)) to my IF sister NMscubagirl


  • I had to go through 16w. Could be worse!  Hang in there. You'll rock this out. :)
    Baby girl Lila born 2013.
    Baby boy Henry born 2015.
    Expecting our capstone baby (boy) early March 2018.
  • I was told PIO until 10 weeks. Thought after I left my RE that the OB would say 8 or 9 was ok - but noooo - he said go to 10 weeks too. I did shave off one day though - just because I felt 9 weeks 6 days wasn't going to change any :) 

    [IMG]http://i39.tinypic.com/30cpoqh.jpg[/IMG]
    Unexplained IF
    IVF #1 3dt 3embies 2/17. +HPT 10p3dt.
    Beta #1-70, #2-130, #3-737, 7w5d no HB :( D&C
    Ivf #2 June ER 6/13 ET 6/18 1 blast 2 morulas
    6dp5dt - BFP!
    Beta 6/27 - 146
  • My last shot is tonight.  I'm 10 weeks.  Had one every night up to 9 weeks and then every other night this last week. 

     

    ***Siggy Warning***

    imageimage
    Anniversary

    Started TTC June 2011
    Cycles #1-10 = BFN
    Cycle #11: 100 mg Clomid + TI =BFN
    Referred to RE March 2012
    HSG all clear, FSH = 13, Prolactin = 28, S/A = great
    April 2012 MRI to check for brain tumor due to elevated Prolactin = clear
    June 2012 Hysteroscopy to remove uterine polyps and partial septate
    July 2012 IUI #1 7/7/12 = BFN
    August 2012 IUI #2.1 Cancelled due to early/missed ovulation = BFN
    September 2012 Forced break due to one huge cyst 
    October 2012 IUI #2.2 = BFN
    November 2012 Begin BCPs for IVF #1
    December 2012 IVF #1 = Delayed due to cyst. Start stims 12/22
    January 2013 ER: 1/2, 14R, 10M, 9F
    ET: 1/7 Transferred 1 "Perfect" blast! 4 frosties!
    Beta #1: 99 BFP! #2: 227 #3: 584 #4: 3,020
    Baby Boy born September 25, 2013

    TTC #2
    November 2014 - Begin BCPs
    December 2014 - Start Lupron 12/25
    January 2015 - FET #1

    Image and video hosting by TinyPic
    *Everyone Welcome*


  • I think I had 8 weeks of PIO and then two weeks of sups.  I hated those shots so much.  I used to have anxiety each night knowing that we still needed to do it.
    together since 2006
    full time stepmom to SS1 and SS2 since 2010
    married since 2011

    TTC since 7/2011 (no planned bc since 2008)
    HSG 11/2011: one blocked tube
    S/A 2/2012 and retest S/A 3/2012: normal
    Bloodwork: normal
    2nd HSG 5/2012: clear
    Femara cycle 5mg #1 7/14/12 + IUI #1 7/23/12 = bfn
    New RE appt 8/14/12
    IVF #1 meds 8/30/12. ER 9/14/2012: 7 retrieved, 6 fertilized. ET 9/19/12: 1 perfect embryo 5dt.
    Beta #1 BFP! 97
    Beta #2 234
    Beta #3 4937
    ultrasound #1 heart beat 127
    10/20/12 graduated!!!
    EDD 6/7/12
    Team PINK!!

    Lilypie Pregnancy tickers

    BabyFruit Ticker
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