Looking for a little sunshine here......my first IVF was BFN. Thanks!
me 40, DH 39... FSH:8.6 AMH 2.3 AFC:15...
DH: MF: sx for Double Varicocele, SA 45 mil, motil: 50%, morph 3%- "lazy swimmers!"...
Me: All "normal" but aging eggs most likely... ;-/
DS: 4/29/05-7 yrs old
MC 9 weeks: 9/21/11
TTC for 3 yrs...7/2012:
1st IUI: BFN 8/2012:
2nd IUI: BFN...
Need a break already!
IVF #1 in progress Jan 2013: Antagonist Prot.: Gonal F 300/Menopur 150
ER: 15 follies, 12 retrieved, 10 mature, 10 fertilized...grow embies grow!
1/8/13: BFN.
Re: Any BFP w/ IVF after 40?
Me:40 AMA, DH:36 0% morph, TTC#1;
BFP#1 4/2011, MMC 6/2011 11wks Trisomy 13;
BFP#2 11/2011, CP
FSH: 17.9, AMH: 2.2
IVF#1 w/ICSI: ER 4/3: 5R,4M,4F
ET 4/6 All 4 (1-8A+, 2-8A-, 1-3A) BFP#3
Two weeks of beta hell = Blighted Ovum
IVF#2 Aug/Sept: ER 8/27: 4R,3M,3F
ET 8/30 (1-8A+, 1-6A+)
Beta#1 9/10: 350; Beta#2 9/12: 796; Beta#3 9/20: 9155
Expecting Boy/Girl Twins! My babies were born 4/23/13 at 36w1d!
Glad you asked this starspangled...it's always nice to see some positive feedback!!!
Sorry IVF#1 was a bust .. try to stay positive!!!! and keep your eye on the prize !
Me = 39 DH = 50 TTC (since 01/2009 after a short break, I stopped counting *cycles* in 2010)
DX 2010 : Unknown Infertility , AMA
HSG 2005 = Normal / HSG 2010 = Normal
SA 2005 = Normal / SA 2010 /2012 = Slightly low count : motility, morphology GREAT!
Chromosomal analysis, MTHFR, ANA's, Lupus, Protein C, Protein S, APCR = Normal 2011
M/C : 2005 (7wk), 2010 (6wk), 2011 (7wk)
8 IUI's 2010-2011 all BFN
IVF/ICSI antagonist 01/2012 #1 = BFN
IVF/ICSI antagonist long 06/2012 #2 = BFN
IVF/ICSI/CGH MDLF New Clinic/New RE 11/2012 #3 = One beautiful boy blasty frozen PGS normal
IVF/ICSI/CGH MDLF 02/2013 #4 = One more beautiful boy blasty frozen PGS normal
FET 6/20 : One 5AA PGS normal transferred Beta 1 6/28 = 53.9 / Beta 2 7/1 = 220 / Beta 3 7/3 = 550!
1 U/S 6w3d - Heartbeat 119 / 2 U/S - 7w5d- Heartbeat 169 / 3 U/S (OB) 8w5d - Heartbeat still great!
Baby G welcomed into the world 3/7/2014
SAIF / PAIF always welcome ****
I am 41. My first IVF with 3 Grade A embryos was a BFN. For the 2nd IVF, I was on DHEA longer than the first time, we did an endometrial biopsy 2 weeks before the IVF cycle and then I also took L-Arginine prior to the transfer to assist with my lining. This time we transferred 3 Grade A embryos, 1 B+ embryo and then a 5th embryo that he didn't give me the grade of. So, yes, we transferred 5 embryos, which is the maximum recommended for our age group. One stuck and I'm now 10 weeks pregnant with my OE!
Good luck to you!!
I'll be 40 in 3.5 weeks, and am pregnant via IVF for the second time. I was fortunate to be successful on the first try each time.
Even though both cycles were successful, I had much better results (egg quantity and quality) on my second cycle back in November, using microdose lupron flare protocol, instead of straight antagonist (basically use microdose lupron the entire stims process instead of the few days of ganirelix), despite pushing 40. My info is in my sig if you want to see the difference in the two protocols.
IVF #1: 9/11: ER: 12R, 11M, 10F, No Frosties; 5dt: 2 blasts, 1 morula; DD born 6/3/12
IVF #2: 11/12-12/12: ER: 20R, 20M, 16F, 4 Frosties; 5dt: 3 blasts, DS born 8/9/13
that is awesome!!!!!! congrats!!!!! and thanks :-)
Congrats!! You all give me hope. I am discouraged bc we did ISCI and AH on this one w/ a 3dt of 3-- 8 cell Grade B embryos, not sure why none of em stuck, but I am trying to keep positive and move on to IVF #2. Congrats to everyone who beat the odds!!! Thanks all :-)
We also did ICSI and AH. I would definitely ask your doctor about an endometrial biopsy. It's super painful (just for the few seconds that they're doing it) but there have been a lot of studies coming out that it may help with implantation.
Sorry, not 40, but i am 39 and 13w with twins from our IVF. I also have a 5 year old that is from our first IVF. We are "unexplained infertility". With our first, we spent more than a year trying everything- testing, hsg, lap, clomid and 4 IUIs before doing IVF. IVF worked the first time for me then.
We knew we were ready for a second child now and we didn't want to waste time or money (out of pocket, our ins doesn't cover fertility) on trying IUIs or other stuff we know didn't work last time, so we jumped right in to IVF first this time. It was a little different- the protocol with my age this time. But I was able to produce some good eggs- retrieved 7, all fertilized and we did a 3 day transfer of 3 embies- 2 excellent and one good. And of course expecting twins out of that. Healthy babies so far at week 13!
Wishing you lots of luck and baby dust.
**ZOMBIE POST!!!**
I doubt OP is still curious a year and a half later!
My BLOG: www.ivfbabyquest.wordpress.com -Update - old blog.
PAIF/SAIF Welcome!
Me: 42, Hubby: 35, TTC since Jan 2010. Dx: DOR due to advanced maternal age. Also: Hypothyroidism (100mcg Levothyroxin). Positive for MTHFR (hetero-C677T), Factor V Leiden, and Fragile X (on DH side). Taking pre-natal vitamins.
First natural PG 9/27/11; mc: 1/20/12
First RE visit: 8/8/12, Saline Sonogram: 8/28/12, IVF injection class: 10/11/12, add FaBB Tab for FVL, +Vitamin D.
IVF #1: 10/17/12 Baseline: FSH- 9.4, E2- 24, LH- 3.7, Prog- 0.3 The u/s showed 6 follicles in my right & 9 in my left. Rx: 150 Bravelle & 150 Menopur SQ nightly. 10/21/12: Add Ganirelix SQ every morning.
ER 10/28/12: 13 Retreived. 7 Mature. 6 Fertilized. 5 Made it to PGS. ET 11/2/12: CANCELED. All 5 came back from PGS as having "severe abnormalities."
IVF #2: 1/7/13 Baseline: FSH- 8.8, 4 follicles in my right & 6 in my left. Rx: 150 Bravelle & 150 Menopur SQ nightly. 1/11/13: Add Ganirelix SQ every morning. hCG Trigger 1/16/13
ER 1/18/13: 9 Retrieved. 5 Mature. 5 Fertilized. 2 Made it to PGS. ET 1/23/13: CANCELED. All embryos (he even sent the ones not growing) came back from PGS as having "multiple severe abnormalities."
IVF #3: NEW RE! 3/1/13 Baseline: FSH- 9.6, E2- 61, Prog- 0.94, 3 follicles in my right & 4 in my left. Rx: 150 Bravelle& 150 Menopur SQ in PM. 3/7/13: Add Ganirelix SQ in AM. hCG Trigger 3/9/13 SQ.
ER 3/11/13: 6R, 2M, 2F. Day 3: one 8 cell, grade 0. Five day ET 3/16/13: one early blast, grade Fair. 3/24/13 AF came a day before beta. BFN
IVF #4: (Added acupuncture to this cycle.) 3/25/13 WTF & Baseline: FSH-11.8, E2- 56, Prog- 0.84 3/26/13 Start stims. 3/30/13 u/s: 5 follicles in my right & 4 in my left. Rx: 225 Bravelle& 225 Menopur SQ in PM. 3/31/13 Add Ganirelix SQ in AM.hCG Trigger 4/3/13 SQ.
ER 4/5/13: 5R, 3M, 3F naturally. Day 3: two 8 cell, grade 0, one 8 cell, grade 2 (Scale 0-best to 3-worst). Five day ET 4/10/13: two blastocysts (the 3rd stopped growing.) Beta 4/18/13: 2.5 BFFN. RE recommends we stop trying and focus on living childless, due to the extremely poor quality of my eggs.
***Decided to stop trying and live CFNBC. I couldn't adjust. So, six months later...
IVF #5: Changed RE. Going to one of the big name clinics now. OWDU: 10/29/13. Update: HORRIBLE experience. Disgusted and distraught at their complete unprofessionalism and how much money and precious time they cost us. Sickening. Have now changed RE again. New Patient appt. 1/30/14.
BFP! Out of nowhere, I got KU the old fashioned way! POAS 1/26/14 - Positive! FDLM 12/30/13. Beta #1 16dpo= 373. Beta #2 18dpo= 801. EDD 10/6/14
2/4/14 1st U/S revealed a 5wk2day sac but no fetal pole. Started 200mgs of progesterone suppositories daily
2/11/14 2nd U/S revealed a perfect 6wk1day "diamond ring" embryo with a beating heart! 138bpm! Add 1mg folic acid and 40mg Lovenox
2/25/14 3rd U/S: perfect 8w1d embryo, 178bpm. 3/6 start spotting. 3/11 10w1d U/S shows no heartbeat. Scheduling D&C. The Stork has forsaken me again.
IVF #5.2: New in-state RE. Supplement priming for 1.5 cycles prior to start of cycle, including DHEA 50mg (stopped 5/15), CoQ10 200mg 2x/day, L-Arginine- 1000mg 2x/day (stopped 6/5 due to cold sore!), myo-inositol- 2g 2x/day, melatonin- 3mg, and Neevo (prenatal for MTHFR).
5/16/14 Day 2 bw cycle prior: FSH- 12.22, E2- 38.37, Prog- 1.35, LH- 9.46. 6/2/14 Day 19 bw: Prog- 23
6/12/14 Baseline: E2- 122.7, Prog- 0.4. 5 follicles in left, 4 follicles in right. Start stims: 375IU Follistim & 150IU Menopur. 6/19 Increase Follistim to 425IU, Menopur still 150IU. 6/18 add Ganirelix. 6/23 Ovidrel trigger SQ. 6/25 ER: 8R, 8M, 5F naturally. Start Medrol & Doxy. 6/26 Start Endometrin. 7/2 Start Lovenox.
7/8/14 Beta= 137.4 BFP!!! (My first from IVF!) E2- 1109, Prog- >60. Stop CoQ10, myo-inositol, and melatonin. 7/9 2nd Beta= 281.4. TSH- 2.70. Increasing Synthroid to 100mcg daily. 7/24 6w3d u/s measured 6w3d, hb: 121bmp! 8/5 8w1d u/s measured 8w3d, hb: 164bpm! Graduated from RE to OB. Now I just need to find an OB!
EDD 3/18/15!