Infertility

Experienced IVFers...Question please!

What's the most number of days you have stimmed?  My antral follie counts are always in the 50-60 range due to my PCOS.  My RE is going to go slow and steady so I feel like I'll stim longer than the 10-15 usual days.  Thank you!
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Re: Experienced IVFers...Question please!

  • I stimmed 11 days with IVF 1. I will either stim 10 or 11 with IVF 2 I hope to know more on Thursday at my third monitoring appointment.
    Dx PCOS 2006 - on Metformin
    Dx Hypothyroid 2009 - on Synthroid
    TTC since 12/2009
    DH - Low Sperm Count

    IVF with ICSI Cycle #1 - October/November- 10/11 Begin Lupron, 10/20 Begin 300iu Gonal-F, Trigger 10/31, ER 11/2, 12 retrieved, 11 mature, 6 fertilized, ET 11/5 - 2 Grade 1 8 cells, 2 frozen blasts (5BA, 3BB), Beta #1 @ 8dp3dt: 7, Beta #2 @ 11dp3dt: 2 :(

    IVF with ICSI Cycle #2 - January - 12/30 Begin Lupron, 1/8 Begin 300iu Gonal-F, ER 1/20, 13 retrieved, 11 mature, 6 fertilized, ET 1/25 - 2 blasts (grades 4BA, 1)

    Everyone Welcome

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  • My IVF cycle I stimmed for 12 days. 
  • IVF 1= 10 days

    IVF 2= 13 days (still suppressed after 3 days of stims, so my stims were bumped up and my cycle recovered) 


    image
    TTC since 10/2010
    IUIs # 1-5 = BFFN
    IVF # 1(July 2012) = BFN
    IVF # 2 (November 2012) = BFP (MIssed MC D&C @ 8w3d on 1/10/13)
    IVF # 3 (June 2013) = BFN 
    IVF # 4 (September 2013) = BFP Fraternal twin boys! (Loss at 21w6d due to IC on 1/26/14...devastated.)
    3/21/14--TAC (transabdominal cerclage) w/Dr. Davis in NJ
    IVF # 5 (May 2014) = BFN
    FET (August 2014) = BFN

    Lilypie Angel and Memorial tickers
  • 12 thats the mjax my RE will go.
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  • 12 thats the max my RE will go.
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  • IVF #1- 10

    IVF#2- Last one today...11days.

    Me:28, DH:30 Married: 07/07/07 TTC Since: March 2011 MFI Me: Possible PAI-1
    April 2012:Varicocele embolization
    IVF #1 July 2012: BFN :( DH- Femara 90 days 
    12/10/2012 Femara helped!
    IVF# 2: Jan 2013 BFP, M/C 6weeks0days
    5 frosties. 
    IVF #3 FET April 2013 BFP, M/C 7 weeks 0 days. 
    3 frosties
  • 10 for first ivf, 9 for the second
    Me: 37, DH: 38: ttc 7 years, dx: unknown
    10/11: after 2 years, saw a RE, FSH 5.4
    11/11: BFP! (surprise after thyroid & normal hsg),
    12/11: missed m/c after 7 week u/s, 1/12: D&C
    6/12 IUI#1-IUI #3: clomid = BFP!, C/P
    IVF #1(10/12) FSH 5.4, AFC: 16 long Lupron, 5R/5M/4F, all 4 made it to 5dt, 1 blast/1-8 cell transferred=BFN
    IVF #2(12/12)AFC 21, MD lupron, 4R/4M/3F, 5dt of 1 blast and 2-8cell. BFN.
    IVF#3(4/13) Natural start antagon protocol, 12R,11F. one PGS normal at day 6 transfer. BFN.
    IVF#4 (11/13) C.CRM (ODW.U normal 8/13 Still no Diagnosis) EPP/antagonist. ER 13R/7M/6F. Only 1 made it to freeze. Abnormal. Looking into options of DE, Fresh vs frozen.
    10/14 new local RE to look into what's next. CD3 FSH 4.7, AMH 0.9. Met with DE agencies and exploring options for feb/march 2015.
    Surprise natural bfp (4 days before donor is signed). Beta #1 at 9dpo: 51.8, 2nd beta: 195 (25 hours doubling) @11dpo. 3rd beta (12/15): 516 (35 hrs doubling) 4th beta(12/17): 895 (58 hours doubling) 5th beta(12/19): 2120. U/S at 5w0d(12/22): one gestational sac with yolk sac. U/S #2 (6w0d)12/29. One little bean measuring 6w0d with HR 124. 3rd u/s(1/4)7w0d: baby measuring 7w2d. HR 134. 3/30: A/S at MFM went great except for low lying placenta. Verifi results are normal! Team Blue! Please send any positive thoughts our way! EDD:8/24/2015
    Baby Will born 8/18. He's perfect.
  • I did 9 days of STIMS. 
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  • My RE won't go beyond 15 days although I have never stimmed more than 10 days.
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  • I stimmed for like 17 or 18 days on m first cycle. (I also have PCOS)
    Lilypie - (5WpR)
    Me(26)PCOS, Hypothyroidism & Incompetent Cervix  DH(28)Azoospermia
    4/11 Off BCPs -- Cycle 1-3 (6months) - No ovulation, Provera
    Cycle 4-6 - Provera, Clomid 50mg, CD23BW - All BFN (HSG-all clear)
    Dec 2011 DH S/A shows zero count - dx Azoo
    TESE 4/13/12 - Sperm found!! 5 viles frozen
    IVF ICSI #1- (Lupron protocol) 5R 2F 2dt- 2DP & 4CF - BFFN
    IVF ICSI #2-  (Antagonist protocol) Started stims 7/26
    ER 8/8 11R 9F 3dt - 9BF & 7BF (+HPT 8dp3dt)TWINS! EDD 5/1/13
    <312/9 Joshua David and Zoe Faith born too early at 19w4d due to incompetent cervix <3
    Lilypie Angel and Memorial tickers
      LAP Transabdominal Cerclage - 4/15/13 only possibility of carrying my children to term 
    IVF#3 - June 2013 -  canceled.
    IVF ICSI #3.2- (Antagonist Protocol) 7/26 start stims (same day, a year later from J & Z's stim start date!)
     ER 8/7 19R 9F 3dt of 2- 8BF embryos. (+HPT 7dp3dt) Beta #1 - 82.8 Beta #2 - 821 Beta #3 - 7254
    9/11/13 - U/S shows 1 baby HR 135bpm! EDD: 4/30/13
    It's a BOY!!
    2/9/14 - DX Gestational Diabetes
    C-section scheduled for 4/7/14 (36w5d)
    Colin Joseph - 1:07pm 6lbs 14oz - 8 days in the NICU
    Everyone Welcome!
  • IVF #1 = 10 days
    IVF #2 = 10 days

    imageimageimageimageimageimageimageimage
    My BLOG: www.ivfbabyquest.wordpress.com -Update - old blog.

    PAIF/SAIF Welcome!
    Me: 42, Hubby: 35, TTC since Jan 2010. Dx: DOR due to advanced maternal age. Also: Hypothyroidism (100mcg Levothyroxin). Positive for MTHFR (hetero-C677T), Factor V Leiden, and Fragile X (on DH side). Taking pre-natal vitamins
    .
    First natural PG 9/27/11; mc: 1/20/12

    First RE visit: 8/8/12, Saline Sonogram: 8/28/12, IVF injection class: 10/11/12, add FaBB Tab for FVL, +Vitamin D.
    IVF #1: 10/17/12 Baseline: FSH- 9.4, E2- 24, LH- 3.7, Prog- 0.3 The u/s showed 6 follicles in my right  & 9 in my left. Rx: 150 Bravelle & 150 Menopur SQ nightly. 10/21/12: Add Ganirelix SQ every morning.
    ER 10/28/12: 13 Retreived. 7 Mature. 6 Fertilized. 5 Made it to PGS. ET 11/2/12: CANCELED. All 5 came back from PGS as having "severe abnormalities."
    IVF #2: 1/7/13 Baseline: FSH- 8.8, 4 follicles in my right & 6 in my left. Rx: 150 Bravelle & 150 Menopur SQ nightly. 1/11/13: Add Ganirelix SQ every morning. hCG Trigger 1/16/13

    ER 1/18/13: 9 Retrieved. 5 Mature. 5 Fertilized. 2 Made it to PGS. ET 1/23/13: CANCELED. All embryos (he even sent the ones not growing) came back from PGS as having "multiple severe abnormalities."
    IVF #3:
    NEW RE! 3/1/13 Baseline: FSH- 9.6, E2- 61, Prog- 0.94, 3 follicles in my right & 4 in my left. Rx: 150 Bravelle& 150 Menopur SQ in PM. 3/7/13: Add Ganirelix SQ in AM. hCG Trigger 3/9/13 SQ.
    ER 3/11/13: 6R, 2M, 2F. Day 3: one 8 cell, grade 0.  Five day ET 3/16/13: one early blast, grade Fair. 3/24/13 AF came a day before beta. BFN

    IVF #4: 
    (Added acupuncture to this cycle.) 3/25/13 WTF & Baseline: FSH-11.8, E2- 56, Prog- 0.84 3/26/13 Start stims. 3/30/13 u/s: 5 follicles in my right & 4 in my left. Rx: 225 Bravelle& 225 Menopur SQ in PM. 3/31/13 Add Ganirelix SQ in AM.hCG Trigger 4/3/13 SQ.
    ER 4/5/13: 5R, 3M, 3F naturally. Day 3: two 8 cell, grade 0, one 8 cell, grade 2 (Scale 0-best to 3-worst). Five day ET 4/10/13: two blastocysts (the 3rd stopped growing.) Beta 4/18/13: 2.5 BFFN. RE recommends we stop trying and focus on living childless, due to the extremely poor quality of my eggs.
    ***Decided to stop trying and live CFNBC. I couldn't adjust. So, six months later...

    IVF #5: Changed RE. Going to one of the big name clinics now. OWDU: 10/29/13. Update: HORRIBLE experience. Disgusted and distraught at their complete unprofessionalism and how much money and precious time they cost us. Sickening. Have now changed RE again. New Patient appt. 1/30/14.
    BFP! Out of nowhere, I got KU the old fashioned way! POAS 1/26/14 - Positive! FDLM 12/30/13. Beta #1 16dpo= 373. Beta #2 18dpo= 801. EDD 10/6/14
    2/4/14 1st U/S revealed a 5wk2day sac but no fetal pole. Started 200mgs of progesterone suppositories daily
    2/11/14 2nd U/S revealed a perfect 6wk1day "diamond ring" embryo with a beating heart! 138bpm! Add 1mg folic acid and 40mg Lovenox
    2/25/14 3rd U/S: perfect 8w1d embryo, 178bpm. 3/6 start spotting. 3/11 10w1d U/S shows no heartbeat. Scheduling D&C. The Stork has forsaken me again.
    IVF #5.2: New in-state RE. Supplement priming for 1.5 cycles prior to start of cycle, including DHEA 50mg (stopped 5/15), CoQ10 200mg 2x/day, L-Arginine- 1000mg 2x/day (stopped 6/5 due to cold sore!), myo-inositol- 2g 2x/day, melatonin- 3mg, and Neevo (prenatal for MTHFR).
    5/16/14 Day 2 bw cycle prior: FSH- 12.22, E2- 38.37, Prog- 1.35, LH- 9.46. 6/2/14 Day 19 bw: Prog- 23
    6/12/14 Baseline: E2- 122.7, Prog- 0.4. 5 follicles in left, 4 follicles in right. Start stims: 375IU Follistim & 150IU Menopur. 6/19 Increase Follistim to 425IU, Menopur still 150IU. 6/18 add Ganirelix. 6/23 Ovidrel trigger SQ. 6/25 ER: 8R, 8M, 5F naturally. Start Medrol & Doxy. 6/26 Start Endometrin. 7/2 Start Lovenox.
    7/8/14 Beta= 137.4 BFP!!! (My first from IVF!) E2- 1109, Prog- >60. Stop CoQ10, myo-inositol, and melatonin. 7/9 2nd Beta= 281.4. TSH- 2.70. Increasing Synthroid to 100mcg daily. 7/24 6w3d u/s measured 6w3d, hb: 121bmp! 8/5 8w1d u/s measured 8w3d, hb: 164bpm! Graduated from RE to OB. Now I just need to find an OB!
    EDD 3/18/15!

  • 11 days both times.

     

    My RE said that for optimal egg quality she prefers to see it between 8 and 12. 

    Age: 35 TTC since 2005, MFI & DOR 

    IVF #1 Sep '11 - canceled poor response

     IVF #2 Nov '11  8R/8M/4F 3dt x2 - chemical

    IVF #3 April '12  11R/6M/4F 3dt x2 - m/c

    FET #1 Aug 2012  3dt x2 - BFN

    **new RE**

     IVF #4 Jan '13 BFN 11R/6M/6F 5dt x2 - BFN

     IVF #5 July '13 16R/10M/10F 5dt x2 + 1 frostie

    9dp5dt Beta 1 = 344!! 16dp5dt. Beta 2 = 4822 7wk u/s= 2 heartbeats!

    Twin girls! 3/6/14

     

  • I was stimming for 12 days and I was sick for every one of them :P  Stimming was the worst part for me.  Everything else was a breeze.
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  • My first ivf was 11 days, my second was 10. My re quoted 812 days on average for stims.
    "Everything will be alright in the end. So if it's not alright, it is not yet the end."
    Me:29 DH:29  TTC since 1/11 Dx: unexplained IF/early DOR/immune issues 
    Feb'12- July'12-testing(all clear minus slight arcuate ute), 3 IUI with clomid all BFN
    8/30IVF#1 Antagonist protocol- ER 9/11-8R, 7M, 5F. 
    ET 9/14 2 embies transferred. 1 10cell Grade 4, 1 8cell Grade 4. No frosties. BFN
    IVF#2 Antagonist protocol plus baby aspirin- ER 12/5-16R, 12M, 8F!
    ET 12/10 5dt! 1 fully expanded blast & 1 early blast. No frosties. BFN
    3/13 hysteroscopy & polypectomy, Consulted w Dr. Kwak-Kim.  
    DX: High NK cells, cytokines, DHEAs& PAI1;  hypothyroid, +APA, restricted bloodflow
    7/13 IVF#3 Long lupron protocol with PIO, Crinone, Prometrium, and vivelle
    (plus synthroid, metformin, baby asa, metanx, PNV, Vit E, D, calcium, fish oil, CoQ10, IVIg infusions and lovenox per Dr. Kwak-kim)
    ER 7/19 14R, 11M, 9F(4 natural fert, 5 with ICSI)
    ET 5dt 7/24 2 fully expanded blasts.  SURPRISE 3 FROSTIES!!!
    Beta #1 8/2 335!!!! Beta #2 829!!!  1st u/s 8/14 showed TWINS!!!!!
    11/11: TEAM PURPLE!!!!!
    3/21/14-L&W born at 37w via csection

    Here Comes the Sun Blog
    PAIF/SAIF welcome!
  • I'm also PCOS- but my AFC isn't quite as high as yours.  The stims for IVF were consistently 10 or 11 days for each of my cycles so far (we've had 4 ERs).
    TTC #1 since 9/2008- 1 year of working with OB using Clomid(unmonitored) resulted in 1 BFP and M/C at 5w6d. Switched and new OB sent me straight to RE. Diagnosed as significant PCOS as well as balanced translocation (me, 10:12) IVF w/ICSI and PGD #1 March 2010, transferred 2 blasts- BFFN, IVF wICSI and PGD #2 June/July 2010 tested and froze on Day 5- only 1 to transfer, FET- BFFN, IVF w/ICSI PGD 3.1- no balanced embies to transfer :-( emotional/physical break- switched to IUI did 6, got a BFP on #2, confirmed c/p IVF #3 w/ICSI, chose to skip PGD- ER was in October 2011- ended up with Massive internal bleeding from both ovaries, admitted to ICU for transfusions (blood and platelets)- freeze all on day 3. I made a full recovery- did FET of 4, day 3 embies (no PGD) BFP! 1 beautiful HB- last live U/S at 9w 4d, at NT discovered no HB, fetus likely stopped growing around 11 w, D&E at 12w, pathology confirmed that the fetus had imbalanced translocation. 6 cycles of trying on own with Ov Induction- 1 BFP and confirmed c/p Oct 2012 IVF #4 Feb 2013? all welcome!
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