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TTC after 35
Mrs.McIrish
member
Destined to Remain in Hell
Mrs.McIrish
member
in TTC after 35
Embryos were horrible. Guess we have an unknown sperm issue too since we took my crappy eggs out of the equation. We put 3 back since they were so bad. Guess we are just supposed to not have kids for some reason. I am throwing in the towel.
TTC #1 since 8/1/10; Me:41 and BRCA1+, DH:46
DOR (FSH 24.3)/ terrible egg quality ; homozygous MTHFR c677t
5 IUI's: 2/11 to 6/11 and 1/12= BFN
OE IVF#1-4 8/11-6/12= all BFN
DE IVF#1 11/12 bad embryos= BFN
DE IVF #2 2/13 BFP/Beta hell: m/c 5w6d
CFNBC 7 months, not doing well; decided on guarantee program at RBA w/frozen DE
DE IVF #3 1/14 ET 4BB; BFP;M/C 5w1d, incomplete m/c; MVA extraction in ER 7w1d
DE FET#1 ET 3/1714; BFP, beta 1 3/27= 197, beta 2 3/31= 1586, beta 3 4/7= 13879!!
First u/s= Twins with HBs at 6w2d! We are Team Pink x 2!!
K & K born 11/21/14 at 38wks 4 days
SAIF/PAIF Welcome
This discussion has been closed.
Re: Destined to Remain in Hell
Nooooo, this can?t be happening to you... There are no words... I am so very sorry. I?m going to start saying my prayers that one those little Stormies is the magic lightening bolt! (((Huge Hug)))
***SIGNATURE WARNING***
TTC #1
Me 42, DH 47
Dx = AMA/DOR, MFI
IVF/ICSI #1 = BFN
IVF/ICSI #2 = BFP; early loss
IVF/ICSI #3 (DE) = BFP; early loss
FET = BFN
IVF/ICSI #4 (DE w/ CCS) = BFP
Beta #1 @ 10dp6dt = 265; Beta #2 @ 14dp6dt = 1251.
1st U/S @ 6w2d showed one perfect little heartbeat!
2nd U/S @ 7w2d. HB 132 & everything measuring on track.
Our beautiful little girl arrived January 2015!
IVF #1 ET 1 d3 embryo 10/30/11 BFP
3 Embryos frozen (1 d5, 2 d6)
DS born 07/29/12
FET #1 ET 1 d5 embryo 02/10/15 BFN
FET #2 1 d6 embryo didn't survive thaw, transferred last d6. CP
Oh no! I'm so sorry. Devastating news!
*Edit: I just re-read that you have three embryos trying to make it. I will definitely keep you in my thoughts and truly hope they succeed!
My BLOG: www.ivfbabyquest.wordpress.com -Update - old blog.
PAIF/SAIF Welcome!
Me: 42, Hubby: 35, TTC since Jan 2010. Dx: DOR due to advanced maternal age. Also: Hypothyroidism (100mcg Levothyroxin). Positive for MTHFR (hetero-C677T), Factor V Leiden, and Fragile X (on DH side). Taking pre-natal vitamins.
First natural PG 9/27/11; mc: 1/20/12
First RE visit: 8/8/12, Saline Sonogram: 8/28/12, IVF injection class: 10/11/12, add FaBB Tab for FVL, +Vitamin D.
IVF #1: 10/17/12 Baseline: FSH- 9.4, E2- 24, LH- 3.7, Prog- 0.3 The u/s showed 6 follicles in my right & 9 in my left. Rx: 150 Bravelle & 150 Menopur SQ nightly. 10/21/12: Add Ganirelix SQ every morning.
ER 10/28/12: 13 Retreived. 7 Mature. 6 Fertilized. 5 Made it to PGS. ET 11/2/12: CANCELED. All 5 came back from PGS as having "severe abnormalities."
IVF #2: 1/7/13 Baseline: FSH- 8.8, 4 follicles in my right & 6 in my left. Rx: 150 Bravelle & 150 Menopur SQ nightly. 1/11/13: Add Ganirelix SQ every morning. hCG Trigger 1/16/13
ER 1/18/13: 9 Retrieved. 5 Mature. 5 Fertilized. 2 Made it to PGS. ET 1/23/13: CANCELED. All embryos (he even sent the ones not growing) came back from PGS as having "multiple severe abnormalities."
IVF #3: NEW RE! 3/1/13 Baseline: FSH- 9.6, E2- 61, Prog- 0.94, 3 follicles in my right & 4 in my left. Rx: 150 Bravelle& 150 Menopur SQ in PM. 3/7/13: Add Ganirelix SQ in AM. hCG Trigger 3/9/13 SQ.
ER 3/11/13: 6R, 2M, 2F. Day 3: one 8 cell, grade 0. Five day ET 3/16/13: one early blast, grade Fair. 3/24/13 AF came a day before beta. BFN
IVF #4: (Added acupuncture to this cycle.) 3/25/13 WTF & Baseline: FSH-11.8, E2- 56, Prog- 0.84 3/26/13 Start stims. 3/30/13 u/s: 5 follicles in my right & 4 in my left. Rx: 225 Bravelle& 225 Menopur SQ in PM. 3/31/13 Add Ganirelix SQ in AM.hCG Trigger 4/3/13 SQ.
ER 4/5/13: 5R, 3M, 3F naturally. Day 3: two 8 cell, grade 0, one 8 cell, grade 2 (Scale 0-best to 3-worst). Five day ET 4/10/13: two blastocysts (the 3rd stopped growing.) Beta 4/18/13: 2.5 BFFN. RE recommends we stop trying and focus on living childless, due to the extremely poor quality of my eggs.
***Decided to stop trying and live CFNBC. I couldn't adjust. So, six months later...
IVF #5: Changed RE. Going to one of the big name clinics now. OWDU: 10/29/13. Update: HORRIBLE experience. Disgusted and distraught at their complete unprofessionalism and how much money and precious time they cost us. Sickening. Have now changed RE again. New Patient appt. 1/30/14.
BFP! Out of nowhere, I got KU the old fashioned way! POAS 1/26/14 - Positive! FDLM 12/30/13. Beta #1 16dpo= 373. Beta #2 18dpo= 801. EDD 10/6/14
2/4/14 1st U/S revealed a 5wk2day sac but no fetal pole. Started 200mgs of progesterone suppositories daily
2/11/14 2nd U/S revealed a perfect 6wk1day "diamond ring" embryo with a beating heart! 138bpm! Add 1mg folic acid and 40mg Lovenox
2/25/14 3rd U/S: perfect 8w1d embryo, 178bpm. 3/6 start spotting. 3/11 10w1d U/S shows no heartbeat. Scheduling D&C. The Stork has forsaken me again.
IVF #5.2: New in-state RE. Supplement priming for 1.5 cycles prior to start of cycle, including DHEA 50mg (stopped 5/15), CoQ10 200mg 2x/day, L-Arginine- 1000mg 2x/day (stopped 6/5 due to cold sore!), myo-inositol- 2g 2x/day, melatonin- 3mg, and Neevo (prenatal for MTHFR).
5/16/14 Day 2 bw cycle prior: FSH- 12.22, E2- 38.37, Prog- 1.35, LH- 9.46. 6/2/14 Day 19 bw: Prog- 23
6/12/14 Baseline: E2- 122.7, Prog- 0.4. 5 follicles in left, 4 follicles in right. Start stims: 375IU Follistim & 150IU Menopur. 6/19 Increase Follistim to 425IU, Menopur still 150IU. 6/18 add Ganirelix. 6/23 Ovidrel trigger SQ. 6/25 ER: 8R, 8M, 5F naturally. Start Medrol & Doxy. 6/26 Start Endometrin. 7/2 Start Lovenox.
7/8/14 Beta= 137.4 BFP!!! (My first from IVF!) E2- 1109, Prog- >60. Stop CoQ10, myo-inositol, and melatonin. 7/9 2nd Beta= 281.4. TSH- 2.70. Increasing Synthroid to 100mcg daily. 7/24 6w3d u/s measured 6w3d, hb: 121bmp! 8/5 8w1d u/s measured 8w3d, hb: 164bpm! Graduated from RE to OB. Now I just need to find an OB!
EDD 3/18/15!
AMA & SAIF. TTC #1 since Oct. 2010. DX: Unexplained. BFP on break after 32 months trying and 2 med cycles. Baby girl born at 40w0d!
jbelle
I'm so sorry.
I hope you get a pleasant surprise.
TICKER WARNING
Oh McIrish =( I am praying one of the three surprises you. Many many hugs. Why the crap does it have to be this hard??!!
I'm so sorry McIrish. I will continue to pray for a miracle. Huge hugs.
Me:40 AMA, DH:36 0% morph, TTC#1;
BFP#1 4/2011, MMC 6/2011 11wks Trisomy 13;
BFP#2 11/2011, CP
FSH: 17.9, AMH: 2.2
IVF#1 w/ICSI: ER 4/3: 5R,4M,4F
ET 4/6 All 4 (1-8A+, 2-8A-, 1-3A) BFP#3
Two weeks of beta hell = Blighted Ovum
IVF#2 Aug/Sept: ER 8/27: 4R,3M,3F
ET 8/30 (1-8A+, 1-6A+)
Beta#1 9/10: 350; Beta#2 9/12: 796; Beta#3 9/20: 9155
Expecting Boy/Girl Twins! My babies were born 4/23/13 at 36w1d!
DOR and AMA
2/12-5/12: 4 IUI cycles = all BFN;
7/12: DE IVF # 1 (with ICSI)- 20R, 16M, 14F, 5DT of 2 blasts; 6 frosties = BFN;
Lupus anticoagulant initially high, then found to be normal on hematology consult;
Follow up testing in September all clear;
Started synthroid for "high normal" TSH;
FET # 1- late October 2012- BFP on FRER; beta # 1- 21(low), beta # 2- 48 (still low), beta # 3- 132, beta # 4- 1,293; beta # 5- 5,606; last beta- over 100,000. First u/s 11/21- heard heartbeat
12/12- Officially an OB patient!
Level 2 ultrasound at 20 weeks shows vasa previa and VCI
Referral to MFM and mandatory c section for delivery
Beautiful baby girl born at 34 weeks
Finally home after 15 day NICU stay!
Trying for sibling: FET # 2- May 2014; beta 5/31, BFN
FET #3, early July 2014; beta 7/14, BFN
DE IVF # 2- August 2014; 14R, 13M, 11F, 5dt of 2 blasts (3 AA), 5 frosties = BFN
FET #4- December 2014, yet another BFN
Dr. KK work up shows borderline uterine blood flow, elevated NK cells, and MTHFR mutation (homozygous for c677t)
Added baby aspirin, prednisone, supplements, Metanx, and intralipids
Switched to large clinic for final attempt; had endometrial receptivity testing in January; FET March 2015 = yet another BFN
Likely OAD- NBC
I am also so very sorry to read this. I don't want to give you false hope, but I would also say that DE embryos that make it to day 5 can in fact be better than they lookafter all, they made it to day 5. Remember that the science is still not advanced enough on this stuff, and sometimes beautiful AA embryos don't implant while crappy ones do. I still think you have a shot here but again, I totally understand why you feel differently. HUGE hugs to you and take it easy while hopefully one of these goes ahead and implants despite your feelings.
1st BFP-8/17/12! Missed Miscarriage discovered @ 8 week US. D&C.
2nd BFP-2/13/13! Blighted Ovum discovered @ 8 week US. Natural miscarriage.
3rd BFP-5/22/13! By early June, progesterone plummeting. Another loss.
August 2013 - started Donor Egg process, but surprise BFP with my own eggs.
Dear Son born 5/28/14
Siggy Warning
I am so so sorry to hear this. I will continue to pray that those three are your fighters and that at least one will be your golden egg. I understand why you feel the way you, so I will stay positive for you.
I am SO sorry.. there are no words that can help but just know I will be thinking of you and hoping for a good outcome. Hugs to you!
TICKER WARNING
McIrish, I am so incredibly sorry to hear things didn't go as expected. I will continue to pray that one of your stormies is as tough as you and sticks it out in there. You are in my thoughts.
IVF #1: 9/11: ER: 12R, 11M, 10F, No Frosties; 5dt: 2 blasts, 1 morula; DD born 6/3/12
IVF #2: 11/12-12/12: ER: 20R, 20M, 16F, 4 Frosties; 5dt: 3 blasts, DS born 8/9/13
Me 38 MH 41 - TTC since June 2010 - dx with Severe MFI. Straight to IVF with ICSI. IVF #1 - ER 06/13/12 - 9 Eggs Retrieved - 4 ICSI'd - only 2 fert. 06/15/12 - 2DT - 3 cell & 6 cell with fragmentation. Beta 06/29/12 - IVF #1 = BFN. 07/20/12 - WTF Appt -Told by our RE to quit IVF. Second Opinion from RE is good. IVF#2 - November 2012. Estradiol Pills Started 11/6. Stims start 11/16. ER 11/26 - 7 eggs retrieved - all mature. 4 fertilized with ICSI. ET 11/29 Transferred 3 embryos. Beta is 12/10. 1st Beta 81 2nd Beta 160 and 3rd beta 360!!! First U/S 12/21/12 - We saw one beautiful gest. sac. 2nd U/S is 01/04/2013 - H/B 183 02/05/13 - NT Scan - everything looks good and IT'S A BOY! Aiden was born 08/20/2013.
IVF #2 is in progress. ER was 05/12/14 - 11 eggs retrieved, 8 fertilized with ICSI. ET was 05/15/14 - we transferred 3 embryos as we did on the cycle my son was conceived. We were able to freeze 3 embryos. Beta is scheduled for 05/26/14. 1st beta - 111. 2nd beta - 159 didn't double
3rd beta Friday 5/30) - not a lot of hope left. Beta # 3 is 247 - probably ectopic. Beta # 4 is 813 - possibly vanishing multiple sydrome? 06/05/14 - 5w4days - first U/S - we see a gestational sac and yolk - still have hope! 06/17/14 - 7w1day - U/S and saw and heard the heartbeat - Finally! 06/27/14 - 8w4days - Baby and heartbeat look and sound great 
EDD 02/01/14 and It's a boy!
"Everything will be okay in the end. If it's not okay, it's not the end."
*** Ticker Warning ***
Well FRAK. This is not what I wanted to hear. I am so very sorry. I wish there was some way we could all make this better for you.
I know it doesn't help, but my Brother and SIL have a beautiful set of triplets that came from 2 very crappy B-team embryos.
HUGS!!!
ME:46 MH:44 DE IVF 2014
Met with RE 4/11. 2 IUI's BFN. DE best option. Switched clinics to do "shared" program. Had to retake all tests and a mamm that put me behind and then on a DE waiting list for 12 months. Picked a donor!! (10/13/13) Got matched. Estimated transfer in December. After 2.5 years of patiently waiting I will finally cycle....can hardly believe it. DE cycle got cancelled. One of her tests came back positive. Waiting for another donor. Donor picked!! (1/18/14)
DE IVF #1 (4/26) BFN DE FET #1 (6/4) BFP! Beta 1=339 Beta 2=852 Beta 3=9957 EDD 2/22/15!!
DS born via unplanned C-section at 40w6d
****Ticker****
I am so sorry McIrish. This just sucks and not the update I was hoping for. I am sure you're done with the emotional roller coaster. Maybe the remaining ones will do their job.
I am praying for your stormies. Praying hard.
I can't believe what I just read.
McIrish, I am so sorry. I can't say anything more that might help. I just really hope that at least one of those 3 ugly ducklings brings an end to this disappointment.
My thoughts are with you.
____________________________
Breast Cancer diagnosis 12/01/2010 - Survivor and Cancer free as of 03/22/2011
BFP#1 04/12/2011 - fetal demise - MC 05/28/2011
BFP#2 10/14/2011 - fetal demise - MC 12/13/2011
BFP#3 05/30/2012 - fetal demise - MC 07/23/2012
IVF#1 02/14/2013 - 2 Beautiful Blasts transferred
BFP#4 02/25/2013 - BFP - MC and ectopic 03/06/2013
IFV#2 07/02/2013 -BFP#5 - 07/07/2013
1st Beta 07/11/2013 - 483 (9dp5dt) - 2nd Beta 07/13/2013 1006 (11dp5dt)
1st U/S 07/31/2013 - TWINS! "The Minions"
IVF#3 BFP#6 09/01/2015 6dp5dt
1st Beta 09/05/2015 - 105 - 2nd Beta 09/08/2015 335
1st U/S 09/22/2015 - .......
My Ovulation Chart