Infertility

PCOS, Metformin, Trigger shot and IUI

I have been diagnosed with PCOS. I tried a round of clomid and the doctor said that my body will not respond to it at all.  I then moved to Metformin and injections which seems to be working.  I am scheduled to do an IUI tomorrow morning and a trigger shot tonight.  Has anyone had this done?  What are the success rates? Also, any other information would be great. Thanks!

Re: PCOS, Metformin, Trigger shot and IUI

  • it seems premature to do the IUI so soon after the trigger.  You ovulate 24-36 hours after , so it's better to wait to get closer to actual release of the egg.

     

     


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  • I agree with pp. I have never heard of doing an Iui 12 hours after injection. Not sure. Are you seeing an RE?
    Me: 37, DH: 38: ttc 7 years, dx: unknown
    10/11: after 2 years, saw a RE, FSH 5.4
    11/11: BFP! (surprise after thyroid & normal hsg),
    12/11: missed m/c after 7 week u/s, 1/12: D&C
    6/12 IUI#1-IUI #3: clomid = BFP!, C/P
    IVF #1(10/12) FSH 5.4, AFC: 16 long Lupron, 5R/5M/4F, all 4 made it to 5dt, 1 blast/1-8 cell transferred=BFN
    IVF #2(12/12)AFC 21, MD lupron, 4R/4M/3F, 5dt of 1 blast and 2-8cell. BFN.
    IVF#3(4/13) Natural start antagon protocol, 12R,11F. one PGS normal at day 6 transfer. BFN.
    IVF#4 (11/13) C.CRM (ODW.U normal 8/13 Still no Diagnosis) EPP/antagonist. ER 13R/7M/6F. Only 1 made it to freeze. Abnormal. Looking into options of DE, Fresh vs frozen.
    10/14 new local RE to look into what's next. CD3 FSH 4.7, AMH 0.9. Met with DE agencies and exploring options for feb/march 2015.
    Surprise natural bfp (4 days before donor is signed). Beta #1 at 9dpo: 51.8, 2nd beta: 195 (25 hours doubling) @11dpo. 3rd beta (12/15): 516 (35 hrs doubling) 4th beta(12/17): 895 (58 hours doubling) 5th beta(12/19): 2120. U/S at 5w0d(12/22): one gestational sac with yolk sac. U/S #2 (6w0d)12/29. One little bean measuring 6w0d with HR 124. 3rd u/s(1/4)7w0d: baby measuring 7w2d. HR 134. 3/30: A/S at MFM went great except for low lying placenta. Verifi results are normal! Team Blue! Please send any positive thoughts our way! EDD:8/24/2015
    Baby Will born 8/18. He's perfect.
  • Actually, I was instructed to trigger at night and IUI the following am if (and only if) an LH surge was detected the day of trigger. Otherwise the timing was ~35 hours later.

    https://www.advancedfertility.com/iui-success-rates.htm

    But of course your dx and the aggressiveness of your treatment makes a difference. Lots of links in the FAQ (in my sig). GL. 

    +++
  • My fertility clinic had me bring the trigger shot with me, did it, had me wait an hour while they washed the sperm, and then did the IUI. I then had a second IUI the next day. I think everywhere does it differently. 
  • For all 4 of my IUIs I triggered 12 hours the night before a scheduled IUI, but we did back to back IUIs.
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  • I guess it is different for everyone and their doctors. I triggered at 9:30pm last night and had my IUI done around 10:30am this morning. Doctor said with the sperm count and follicles we have a 20% chance of pregnancy and 17% of twins! Fingers crossed!!! 
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